CN214385488U - Excrement-liquid separating device and animal metabolism cage - Google Patents

Excrement-liquid separating device and animal metabolism cage Download PDF

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Publication number
CN214385488U
CN214385488U CN202022676508.7U CN202022676508U CN214385488U CN 214385488 U CN214385488 U CN 214385488U CN 202022676508 U CN202022676508 U CN 202022676508U CN 214385488 U CN214385488 U CN 214385488U
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urine
excrement
outlet
separation device
collector
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CN202022676508.7U
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Inventor
周春娣
李建祥
张末初
王丽洁
梁羽
杨雪萍
孙万平
李笃信
孙国伟
袁海浪
褚芸
邱飘飘
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Suzhou Suda health and Environmental Technology Research Institute Co.,Ltd.
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Sanitation & Environment Technology Institute Soochow University
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Abstract

The utility model discloses a liquid dung separating device and an animal metabolism cage, which comprises a funnel-shaped excrement collector for collecting excrement, wherein the bottom of the excrement collector is provided with a urine outlet, and a grid-shaped sieve plate for sealing the urine outlet is obliquely arranged above the urine outlet; a urine collecting bottle is arranged below the urine outlet; the excrement collector is characterized in that an excrement outlet is formed in the side wall of the excrement collector, the bottom of the sieve plate is arranged below the excrement outlet, and the excrement outlet is connected with an excrement collecting bottle. The utility model discloses effectively compensate the shortcoming of current metabolism cage, optimize the upgrading to the device. By using the grid baffle, the excrement and urine enter the excrement-urine separation module. Wherein, the urine naturally flows down and enters a urine pretreatment module containing a purification column; the faeces slide down the faeces duct through the inclined sieve plate in the urine collection chamber. Not only can realize timely separation of the liquid dung, but also can finish primary separation and enrichment of urine target components, and prevent mutual interference among the urine components.

Description

Excrement-liquid separating device and animal metabolism cage
Technical Field
The utility model relates to a biological sample separation collection device especially relates to a liquid dung separator and animal metabolism cage.
Background
In animal experiments, metabolic components in urine or feces of experimental animals are often required to be collected so as to measure toxicants, metabolites, biochemical indexes and the like. In order to collect effective and pure biological samples of feces or urine, the mice/rabbits are required to be metabolized in a cage, and the feces and urine of the mice/rabbits are required to be separated and enriched in time. Prevents mutual interference and pollution, and influences the analysis of the biological sample and the judgment of the result.
The metabolic cages currently available on the market, although able to fulfill the basic purpose of separating the feces from the urine, are not able to screen the biological samples for the first time and present the risk of mutual contamination. Excrement collector on the market mainly intercepts excrement, and urine flows into bottom urine collector, and excrement and urine gathers in middle part wedge funnel-shaped separator always, and in the urine enrichment process, excrement and urine is always eluviated by urine, is in the moist state of softening. On one hand, urine is polluted by excrement, on the other hand, effective excrement samples cannot be collected after excrement is softened, and finally excrement and urine biological samples are mutually interfered and polluted, so that judgment and analysis of results are influenced.
In addition, the device also exists in the market, utilizes the parabola principle, and the metabolism cage which separates and enriches the excrement and urine in time respectively can avoid the mutual interference and pollution of the urine and the excrement, but can not primarily separate and enrich the target components in the urine.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a liquid dung separator and applied this liquid dung separator's animal metabolism cage that carries out preliminary separation and enrichment to target component in the urine.
In order to achieve the above object, the utility model provides a following technical scheme:
a liquid dung separating device comprises a funnel-shaped excrement collector for collecting excrement, wherein a urine outlet is formed in the bottom of the excrement collector, and a grid-shaped sieve plate for closing the urine outlet is obliquely arranged above the urine outlet; a urine collecting bottle is arranged below the urine outlet; the excrement collector is characterized in that an excrement outlet is formed in the side wall of the excrement collector, the bottom of the sieve plate is arranged below the excrement outlet, and the excrement outlet is connected with an excrement collecting bottle.
Preferably, the faecal collector is defined by a plurality of plate-shaped baffles enclosing a funnel-shaped structure.
Preferably, the upper part of a tubular excrement conduit is communicated with the excrement outlet, and the lower part of the tubular excrement conduit is communicated with the excrement collecting bottle.
Preferably, set up an urine preliminary treatment module between urine export and the urine receiving flask, urine preliminary treatment module includes the barrel of a both ends open-ended cylinder, be provided with the purification post that carries out the preliminary treatment to the urine in the barrel, both ends all are provided with the net baffle about the purification post, the barrel below is through a collection urine pipe intercommunication the urine receiving flask.
Preferably, the grid baffle is made of PE, PP or stainless steel, and the aperture of the grid baffle is 20-200 μm.
Preferably, the purification column is composed of an adsorbent filled in the cylinder, and the adsorbent is macroporous adsorption resin, silica gel chromatographic packing or activated carbon.
Preferably, the sieve plate is a hollow plate with transverse grains or vertical grains, and the width of the gap of the hollow plate is 0.1-1 mm.
Preferably, the inclination angle range of the sieve plate is 15-60 degrees, and the sieve plate is made of stainless steel or hard smooth plastic.
The utility model also provides an animal metabolism cage, it includes excrement liquid separator and a support, set up the cage body on the support, excrement liquid separator sets up the below of the cage body.
Preferably, the bottom of the cage body is provided with a grid-shaped bottom plate.
The utility model discloses effectively compensate the shortcoming of current metabolism cage, optimize the upgrading to the device. By using the grid baffle, the excrement and urine enter the excrement-urine separation module. Wherein, the urine naturally flows down and enters a urine pretreatment module containing a purification column; the faeces slide down the faeces duct through the inclined sieve plate in the urine collection chamber. Not only can realize timely separation of the liquid dung, but also can finish primary separation and enrichment of urine target components, and prevent mutual interference among the urine components. For example, urine passes through a solid phase extraction column for preliminary screening, compounds with small polarity are adsorbed by a purification column, and components with large polarity, such as saccharides, do not adsorb and naturally flow into a urine collector. The purification column in the device belongs to a detachable form, not only can collect the components which are not reserved, but also can elute and collect the adsorbed components in the column according to the actual requirement, thereby realizing the primary separation and collection of the components with various properties.
Drawings
FIG. 1 is a schematic structural view of the animal metabolism cage of the present invention;
figure 2 is an enlarged view of a portion of the urine pretreatment module.
Wherein: cage 1, bottom plate 2, sieve 3, baffle 4, baffle 5, baffle 6, collection urine pipe 8, urine receiving flask 9, excrement and urine pipe 10, excrement and urine receiving flask 11, go up grid baffle 15, purification post 16, lower grid baffle 17, urine export 18, excrement and urine export 19, barrel 20.
Detailed Description
The technical solution of the present patent will be described in further detail with reference to the following embodiments.
As shown in figures 1 to 2, the animal metabolism cage of the present invention comprises a support 13, a cage body 1 is arranged on the support 13, the length, width and height of the cage body 1 are 20cm, 30cm and 20cm respectively, and a grid-shaped bottom plate 2 is arranged at the bottom of the cage body 1. The gap of the bottom plate 2 is 0.5x0.5cm, and the device is suitable for both rats and mice.
A liquid dung separating device is arranged below the cage body 1. The liquid-dung separating device comprises a funnel-shaped device for collecting the dung, which is enclosed by a plate-shaped baffle 4, a baffle 5 and a baffle 6 and is shaped like a funnel-shaped structure. The bottom of the faecal collector is provided with a urine outlet 18 and above the urine outlet 18 a grid-like sieve plate 3 is obliquely arranged closing the urine outlet 18. The excrement outlet 19 is arranged on the side wall of the excrement collector, the bottom of the sieve plate 3 is arranged below the excrement outlet 19, the urine collecting bottle 9 is arranged below the urine outlet 18, and the excrement outlet 19 is connected with the excrement collecting bottle 11.
The deflection angle of the sieve plate 3 relative to the horizontal clockwise is 30 degrees; the width of the narrow slit transverse stripe inclined plate slit of the sieve plate 3 is 1mm, the caliber of the excrement outlet 19 is 2cm, and excrement enters a 500mL stainless steel excrement collecting bottle 11 with a cover through an excrement conduit 10 through the excrement outlet 19.
A urine pre-treatment module is arranged between the urine outlet 18 and the urine collection bottle 9. The urine pretreatment module is a solid phase extraction column, which is a C18 column and comprises a cylindrical barrel 20 with two open ends. A purifying column 16 for pretreating urine is arranged in the cylinder body 20, an upper grid baffle 15 and a lower grid baffle 17 are arranged at the upper end and the lower end of the purifying column 16, and the lower part of the cylinder body 20 is communicated with a urine collecting bottle 9 through a urine collecting pipe 8. The aperture of the grid baffle is 20 mu m; the solid phase extraction column had an internal diameter of 1.5cm and a length of 5 cm.
Preferably, the grid baffle is made of PE, PP or stainless steel, and the pore diameter of the grid baffle is 20-200 μm.
Preferably, the purifying column 16 is composed of an adsorbent filled in the cylinder 20, and the adsorbent is macroporous adsorbent resin, silica gel chromatographic packing or activated carbon.
Preferably, the screen plate 3 is a hollow plate with transverse lines or vertical lines, and the gap width of the hollow plate is 0.1-1 mm.
Preferably, the inclination angle of the sieve plate 3 ranges from 15 to 60 degrees, and the sieve plate 3 is made of stainless steel or hard smooth plastic.
The working principle is as follows: the rat/mouse moves in the cage body 11, diet and defecation are carried out, the produced excrement falls into the excrement-liquid separation device through the excrement collecting bottle 11, the excrement is intercepted by the sieve plate 3, enters the excrement guide pipe 10 through the excrement outlet 19 and finally enters the excrement collecting bottle 11. Urine flows into urine preprocessing module through the striation gap nature of sieve 3, gets into purification column 16 through last grid baffle 15, and the little component of polarity is adsorbed by purification column 16, and the material that the polarity is big is not kept like carbohydrate, through lower grid baffle 17, flows into urine collection pipe 8, flows into the urine collector through urine collection pipe 8 again, according to the nature of sample component polarity, with urine component initial segregation.
The utility model discloses can be under the normal activity of mouse that does not influence big/little to and the condition of not demolising the metabolism cage, the excrement and urine and the urine of convenient collection big/mouse.
It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (10)

1. The utility model provides a liquid dung separator, includes the excrement and urine collector that is used for collecting excrement and urine of infundibulate, its characterized in that: a urine outlet is arranged at the bottom of the excrement collector, and a grid-shaped sieve plate for closing the urine outlet is obliquely arranged above the urine outlet; a urine collecting bottle is arranged below the urine outlet; the excrement collector is characterized in that an excrement outlet is formed in the side wall of the excrement collector, the bottom of the sieve plate is arranged below the excrement outlet, and the excrement outlet is connected with an excrement collecting bottle.
2. A liquid manure separation device according to claim 1, wherein: the excrement collector is a funnel-shaped structure formed by a plurality of plate-shaped baffles in a surrounding mode.
3. A liquid manure separation device according to claim 2, wherein: the upper part of a tubular excrement conduit is communicated with the excrement outlet, and the lower part of the tubular excrement conduit is communicated with the excrement collecting bottle.
4. A liquid manure separation device according to claim 1, wherein: set up an urine preliminary treatment module between urine export and the urine receiving flask, urine preliminary treatment module includes the barrel of a both ends open-ended cylinder, be provided with in the barrel and carry out the purification post of preliminary treatment to the urine, both ends all are provided with the net baffle about the purification post, the barrel below is through a collection urine pipe intercommunication the urine receiving flask.
5. A liquid manure separation device according to claim 4, wherein: the grid baffle is made of PE, PP or stainless steel, and the aperture of the grid baffle is 20-200 mu m.
6. A liquid manure separation device according to claim 4, wherein: the purifying column is composed of an adsorbent filled in the cylinder, and the adsorbent is macroporous adsorption resin, silica gel chromatographic packing or activated carbon.
7. A liquid manure separation device according to claim 1, wherein: the sieve plate is a hollow plate with transverse grains or vertical grains, and the width of the gap of the hollow plate is 0.1-1 mm.
8. A liquid manure separation device according to claim 7, wherein: the inclination angle range of the sieve plate is 15-60 degrees, and the sieve plate is made of stainless steel or hard smooth plastics.
9. An animal metabolism cage comprising a manure separation device according to any one of claims 1 to 8, wherein: the excrement-liquid separation device comprises a support, wherein a cage body is arranged on the support, and the excrement-liquid separation device is arranged below the cage body.
10. The animal metabolism cage of claim 9, wherein: the bottom of the cage body is provided with a grid-shaped bottom plate.
CN202022676508.7U 2020-11-18 2020-11-18 Excrement-liquid separating device and animal metabolism cage Active CN214385488U (en)

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Application Number Priority Date Filing Date Title
CN202022676508.7U CN214385488U (en) 2020-11-18 2020-11-18 Excrement-liquid separating device and animal metabolism cage

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116250490A (en) * 2023-05-09 2023-06-13 潍坊医学院 Multi-module large/mouse metabolism cage compatible with IVC system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116250490A (en) * 2023-05-09 2023-06-13 潍坊医学院 Multi-module large/mouse metabolism cage compatible with IVC system

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Address after: 215000 rooms 101, 201, 301, 401 and 501, building 2, No. 188, Fuchunjiang Road, high tech Zone, Suzhou, Jiangsu

Patentee after: Suzhou Suda health and Environmental Technology Research Institute Co.,Ltd.

Address before: 215000 No. 463, Shizi street, Suzhou, Jiangsu

Patentee before: SANITATION & ENVIRONMENT TECHNOLOGY INSTITUTE, SOOCHOW University