CN214232870U - Liquid chromatography separation column - Google Patents
Liquid chromatography separation column Download PDFInfo
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- CN214232870U CN214232870U CN202022784987.4U CN202022784987U CN214232870U CN 214232870 U CN214232870 U CN 214232870U CN 202022784987 U CN202022784987 U CN 202022784987U CN 214232870 U CN214232870 U CN 214232870U
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- column
- liquid chromatography
- locking
- plug cover
- chromatography separation
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Abstract
The utility model discloses a liquid chromatography separation column, which comprises a column body, at least one plug cover and a locking part, wherein the column body is provided with a column cavity; the plug cap at least partially fits into the column cavity of the column; the locking component is suitable for connecting the column body and the plug cover so as to lock the column body and the plug cover. The assembly is convenient, and the assembly of a large-size liquid phase separation column is convenient.
Description
Technical Field
The utility model relates to a liquid chromatography separation column.
Background
Currently, the flash liquid chromatography technique is a form of rapid preparative column chromatography based on pressure generated by a pump to accelerate the elution rate of a mobile phase through a pre-packed chromatographic separation column, the core component of which is a liquid chromatographic separation column. The separation principle is as follows: dissolving a mixture sample in a mobile phase, and enabling the mixture sample to pass through a stationary phase adsorbent filled in a chromatographic separation column at a certain speed, wherein because the solubility of each component of the mixture in the stationary phase is different from that of the mobile phase, namely the distribution coefficients of the components in the two phases are different, the components of the mixture flow through the stationary phase adsorbent at different speeds, thereby achieving the purpose of separation; the plug cap of the prior art liquid chromatography separation column is usually screwed on the column body by screw threads, but for the large-size liquid chromatography separation column, the screwing is extremely inconvenient and the assembly is inconvenient due to the large diameter of the column body.
Disclosure of Invention
The utility model aims to solve the technical problem that overcome prior art's defect, provide a liquid chromatography separation post, it equipment is convenient, the equipment of the large size liquid chromatography separation post of being convenient for.
In order to solve the technical problem, the technical scheme of the utility model is that: a liquid chromatography separation column comprising:
a cylinder provided with a cylinder cavity;
at least one plug cap that fits at least partially into the column cavity of the column;
a locking member adapted to connect the cylinder and the plug to lock the cylinder and the plug.
Further, the locking member is adapted to connect the respective end side wall of the cylinder and the outer peripheral portion of the plug cover.
Further, the locking component comprises a locking assembly or at least two locking assemblies; wherein the content of the first and second substances,
all the locking assemblies in the locking member are arranged along the circumference of the closure.
Furthermore, the locking component is a locking screw, and the locking screw is connected with the column body and then is in threaded connection with the plug cover.
Further, in order to protect the column body when the column body is stressed, a separation hoop is arranged on the column body, and the separation hoop at least separates the head of the locking screw from the column body.
Further, the plug cover is provided with an accommodating groove;
the locking assembly comprises a screw and a nut, and the screw is connected with the cylinder and the plug cover and then is in threaded connection with the corresponding nut in the accommodating groove.
Further, in order to protect the column body when stressed, an outer space ring is arranged on the column body and at least separates the nail head of the screw from the column body.
Further, in order to protect the plug cover when the plug cover is stressed, an inner spacer ring is arranged in the containing groove of the plug cover and at least separates the nut from the plug cover.
Furthermore, the containing groove is an annular groove which takes the center of the plug cover as the center of a circle.
Furthermore, two plug covers are arranged and are respectively positioned at two end parts of the column cavity of the column body;
it still includes:
two sieve plates which are positioned in the column cavity and are arranged at the inner side of the corresponding plug cover, and a stationary phase adsorbent is arranged in the column cavity between the two sieve plates.
After the technical scheme is adopted, the utility model discloses an among the liquid chromatography separation column's the structure, through the tip of the post chamber with gag tight fit income cylinder, then through locking Assembly edgewise with gag and cylinder locking, avoided the former phenomenon inconvenient is twisted soon through what bring gag and cylinder threaded connection, be particularly useful for the liquid chromatography separation column of major diameter.
Drawings
FIG. 1 is a schematic diagram of a liquid chromatography column of a first configuration according to the present invention;
FIG. 2 is a cross-sectional view A-A of FIG. 1;
FIG. 3 is a schematic diagram of a second configuration of a liquid chromatography column according to the present invention;
fig. 4 is a sectional view B-B of fig. 3.
Detailed Description
In order that the present invention may be more readily and clearly understood, the following detailed description of the present invention is provided in connection with the accompanying drawings.
Example one
As shown in fig. 1 to 2, a liquid chromatography column comprises:
the column body 1 is provided with a column cavity 11;
at least one plug 2, said plug 2 at least partially fitting into the column cavity 11 of said column body 1;
locking means adapted to connect the cylinder 1 and the plug 2 to lock the cylinder 1 and the plug 2.
Specifically, as shown in fig. 1, in the present embodiment, two plugs 2 are provided and are respectively located at two ends of the column cavity 11 of the column body 1;
specifically, as shown in fig. 1, it further includes:
two sieve plates 8 which are positioned in the column cavity 11 and are arranged at the inner side of the corresponding plug cover 2, and a fixed phase adsorbent is arranged in the column cavity 11 between the two sieve plates 8.
Specifically, the upper plug cover 2 is provided with an inlet 22, and the lower plug cover 2 is provided with an outlet 23.
More specifically, the plug cover 2 is provided with a flow guide structure on a surface facing the corresponding sieve plate 8, so that the liquid phase is uniformly distributed to the stationary phase adsorbent through the sieve plate 8 by the flow guide structure.
In particular, the locking means are suitable for connecting the respective end side walls of the cylinder 1 and the peripheral portion of the plug 2.
In particular, the locking means may comprise one locking assembly, but may of course comprise at least two locking assemblies; in fig. 2, there are 8 locking assemblies, wherein,
all the locking components in the locking components are arranged along the circumferential direction of the plug cover 2, and can be uniformly distributed or non-uniformly distributed.
In the embodiment, as shown in fig. 1, the locking component is a locking screw 3, and the locking screw 3 is connected with the cylinder 1 and then is in threaded connection with the plug 2.
In order to protect the column body 1 when a force is applied, a separation hoop 4 is arranged on the column body 1, and the separation hoop 4 at least separates the head of the locking screw 3 from the column body 1.
Through the tip of the column chamber 11 with gag 2 tight fit in cylinder 1, then lock gag 2 and cylinder 1 from the side through locking Assembly, avoided earlier through the inconvenient phenomenon of twisting that brings gag 2 and cylinder 1 threaded connection, be particularly useful for the liquid chromatography separation column of major diameter.
Example two
The structure of this embodiment is substantially the same as that of the first embodiment, except that:
as shown in fig. 3 to 4, the plug cover 2 is provided with an accommodating groove 21;
the locking assembly comprises a screw 51 and a nut 52, and the screw 51 is connected with the cylinder 1 and the plug cover 2 and then is in threaded connection with the corresponding nut 52 in the accommodating groove 21.
As shown in fig. 3 to 4, in order to protect the column 1 when a force is applied, an outer spacer 6 is provided on the column 1, and the outer spacer 6 at least separates the head of the screw 51 from the column 1.
As shown in fig. 3 to 4, in order to protect the plug 2 when a force is applied, an inner spacer 7 is disposed in the receiving groove 21 of the plug 2, and the inner spacer 7 at least separates the nut 52 from the plug 2.
As shown in fig. 3 to 4, the accommodating groove 21 is an annular groove with the center of the plug 2 as the center.
The above-mentioned embodiments further explain in detail the technical problems, technical solutions and advantages solved by the present invention, and it should be understood that the above only is a specific embodiment of the present invention, and is not intended to limit the present invention, and any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the scope of the present invention.
In the description of the present invention, it is to be understood that the terms indicating orientation or positional relationship are based on the orientation or positional relationship shown in the drawings, and are only for convenience of description and simplification of description, and do not indicate or imply that the equipment or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate the position or positional relationship based on the position or positional relationship shown in the drawings, or the position or positional relationship which is usually placed when the product of the present invention is used, and are only for convenience of description and simplification of the description, but do not indicate or imply that the device or element referred to must have a specific position, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance.
Furthermore, the terms "horizontal", "vertical", "overhang" and the like do not imply that the components are required to be absolutely horizontal or overhang, but may be slightly inclined. For example, "horizontal" merely means that the direction is more horizontal than "vertical" and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.
In the present disclosure, unless otherwise expressly stated or limited, the first feature may comprise both the first and second features directly contacting each other, and also may comprise the first and second features not being directly contacting each other but being in contact with each other by means of further features between them. Also, the first feature being above, on or above the second feature includes the first feature being directly above and obliquely above the second feature, or merely means that the first feature is at a higher level than the second feature. A first feature that underlies, and underlies a second feature includes a first feature that is directly under and obliquely under a second feature, or simply means that the first feature is at a lesser level than the second feature.
Claims (9)
1. A liquid chromatography separation column, comprising:
the column body (1), the column body (1) is provided with a column cavity (11);
at least one plug (2), the plug (2) fitting at least partially into a column chamber (11) of the column body (1);
a locking component which is suitable for connecting the column body (1) and the plug cover (2) to lock the column body (1) and the plug cover (2); wherein the content of the first and second substances,
the locking component comprises a locking assembly or at least two locking assemblies;
all the locking components are arranged along the circumference of the plug cover (2).
2. A liquid chromatography separation column according to claim 1,
the locking means are adapted to connect the respective end side walls of the column (1) and the peripheral portion of the closure (2).
3. A liquid chromatography separation column according to claim 1,
the locking assembly is a locking screw (3), and the locking screw (3) is connected with the column body (1) and then is in threaded connection with the plug cover (2).
4. A liquid chromatography separation column according to claim 3,
the column body (1) is provided with a separating hoop (4), and the separating hoop (4) at least separates the nail head of the locking screw (3) from the column body (1).
5. A liquid chromatography separation column according to claim 1,
the plug cover (2) is provided with a containing groove (21);
the locking assembly comprises a screw (51) and a nut (52), and the screw (51) is connected with the column body (1) and the plug cover (2) and then is in threaded connection with the corresponding nut (52) in the accommodating groove (21).
6. A liquid chromatography separation column according to claim 5,
an outer space ring (6) is arranged on the column body (1), and the outer space ring (6) at least separates the nail head of the screw (51) from the column body (1).
7. A liquid chromatography separation column according to claim 5,
an inner spacer ring (7) is arranged in the containing groove (21) of the plug cover (2), and the inner spacer ring (7) at least separates the nut (52) from the plug cover (2).
8. A liquid chromatography separation column according to claim 5,
the containing groove (21) is a ring groove which takes the center of the plug cover (2) as the center of a circle.
9. A liquid chromatography separation column according to claim 1,
the two plug covers (2) are respectively positioned at two ends of the column cavity (11) of the column body (1);
it still includes:
the two sieve plates (8) are positioned in the column cavity (11) and arranged on the inner side of the corresponding plug cover (2), and a stationary phase adsorbent is arranged in the column cavity (11) between the two sieve plates (8).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022784987.4U CN214232870U (en) | 2020-11-26 | 2020-11-26 | Liquid chromatography separation column |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022784987.4U CN214232870U (en) | 2020-11-26 | 2020-11-26 | Liquid chromatography separation column |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214232870U true CN214232870U (en) | 2021-09-21 |
Family
ID=77734701
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022784987.4U Active CN214232870U (en) | 2020-11-26 | 2020-11-26 | Liquid chromatography separation column |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214232870U (en) |
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2020
- 2020-11-26 CN CN202022784987.4U patent/CN214232870U/en active Active
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