CN213965702U - Nucleic acid aerosol purifies safety cover - Google Patents

Abstract

The utility model relates to the technical field of nucleic acid aerosol purification devices, in particular to a nucleic acid aerosol purification protective cover, which is a box body provided with a hollow cavity, wherein the box body is provided with a detachable bottom plate, the box body is provided with an air inlet and an air outlet, the air inlet is covered with an aerosol filter membrane, and an air inlet cover is movably arranged outside the aerosol filter membrane; the air exit border is equipped with the one-way elastic film that makes the air only can flow in but can't flow in and be equipped with the through-hole in the middle from the box in following the cavity, the air exit outer activity is equipped with the exhaust flap. The utility model aims to overcome prior art and need consume the not enough of expensive cost could provide the experimental environment who is not polluted by nucleic acid aerosol, provide a low cost's simple and easy nucleic acid aerosol purification safety cover.

Description

Nucleic acid aerosol purifies safety cover

Technical Field

The utility model relates to a nucleic acid aerosol purifier technical field, more specifically relates to a nucleic acid aerosol purifies safety cover.

Background

In many biological laboratories, molecular biology detection methods such as PCR have been widely used due to their advantages of high sensitivity, rapidity, and convenient operation, but due to its extremely high sensitivity, trace contamination sources may cause false positives in detection results, and environmental pollution is also strictly controlled. The aerosol pollution is an important factor influencing the detection result, the aerosol is a colloid dispersion system formed by dispersing small solid or liquid particles in a gas medium, and the aerosol can be formed when air rubs against a liquid surface, for example, a reaction tube is violently shaken during operation, and the sample is uncovered, sucked and repeatedly sucked by a polluted sample injection gun. Generally, a fresh air system is installed in an experimental environment to reduce aerosol pollution, but the price of the fresh air system is expensive, and a nucleic acid aerosol removing reagent for removing nucleic acid aerosol pollution is expensive, so that a large amount of cost is consumed when the nucleic acid aerosol removing reagent is used in the whole experimental space, and the method is not environment-friendly and is not economical.

Chinese patent publication No. CN202044961U discloses a gas purification glove box for chemical experiments, which can make experimental operations performed in the glove box, reduce the pollution of gas to the environment during the experiment, and although a narrow space is provided by a reference document, it does not have the function of filtering nucleic acid aerosol in the air, and cannot ensure that the air in the glove box is not polluted by nucleic acid aerosol, so that it cannot provide a low-cost experimental environment which is not polluted by nucleic acid aerosol.

SUMMERY OF THE UTILITY MODEL

The utility model aims to overcome prior art and need consume the not enough of expensive cost could provide the experimental environment who is not polluted by nucleic acid aerosol, provide an accessible and dwindle the clean space and reduce the simple and easy nucleic acid aerosol purification safety cover that uses nucleic acid aerosol to clear away reagent quantity and keep not polluted by nucleic acid aerosol in the experimental process in the experimental space.

In order to solve the technical problem, the utility model discloses a technical scheme is:

providing a nucleic acid aerosol purification protective cover, wherein the nucleic acid aerosol purification protective cover is a box body provided with a hollow cavity, the box body is provided with a detachable bottom plate, the box body is provided with an air inlet and an air outlet, an aerosol filter membrane is covered on the air inlet, and an air inlet cover is movably arranged outside the aerosol filter membrane; the air exit border is equipped with the one-way elastic film that makes the air only can flow in but can't flow in and be equipped with the through-hole in the middle from the box in following the cavity, the air exit outer activity is equipped with the exhaust flap.

The utility model achieves the purpose of reducing the usage amount of nucleic acid aerosol removing reagent by providing a nucleic acid aerosol purifying protective cover with a smaller space, thereby reducing the cost; the bottom plate detachably connected with the box body is convenient for separating the bottom plate from the nucleic acid aerosol purification protective cover, when in use, the experimental device is placed on the bottom plate, and then the nucleic acid aerosol purification protective cover is covered on the bottom plate, so that the experimental device is placed inside the nucleic acid aerosol purification protective cover; or directly sleeving the nucleic acid aerosol purification protection cover with the bottom plate removed outside the experimental device; meanwhile, aerosol in the air outside the nucleic acid aerosol purification protective cover is filtered through an aerosol filter membrane arranged on the air inlet, so that the space in the nucleic acid aerosol purification protective cover is prevented from being polluted by the aerosol, an air outlet is arranged so that an experimenter can conveniently stretch hands into the aerosol purification protective cover to carry out experimental operation in an experiment, a one-way elastic film arranged on the air outlet has elasticity and is one-way, when the experimenter stretches hands into the aerosol purification protective cover from a through hole of the one-way elastic film to carry out experimental operation, the one-way elastic film is attached to the outer side of the hand of the experimenter, so that the air cannot flow in from the air outlet, the effect of keeping the air in the nucleic acid aerosol purification protective cover from being polluted by the nucleic acid aerosol is initially kept, and due to the one-way property of the elastic film, the air can flow out from the elastic film in the nucleic acid aerosol purification protective cover, the heat dissipation function can be enhanced. Thus, an experimental space which is not contaminated by nucleic acid aerosol can be obtained at a low cost.

The operation principle is as follows: the bottom plate of the nucleic acid aerosol purification protective cover is detached, the experimental device is placed on the bottom plate, and then the nucleic acid aerosol purification protective cover is covered on the bottom plate and is installed and connected with the bottom plate again; or the nucleic acid aerosol purification protective cover is directly sleeved outside the experimental device; then, the nucleic acid aerosol removing reagent is used for reacting with the nucleic acid aerosol in the nucleic acid aerosol purification protection cover to purify the gas in the nucleic acid aerosol purification protection cover, the air inlet and the air outlet are opened, a hand extends into the nucleic acid aerosol purification protection cover from the air outlet to perform experiment operation until the experiment is completed, the air inlet and the air outlet are closed, the bottom plate is detached, and the bottom plate is installed back to the nucleic acid aerosol purification protection cover after the experiment device is taken out.

Preferably, the box includes the frame, with frame attach's roof, with frame attach and the first panel, second panel, third panel, the fourth panel that set up in order, the bottom plate with the connection can be dismantled to the frame, the air intake establish with on the first panel, the air exit establish with on the third panel that first panel is in opposite directions.

Preferably, the cross-sectional area of the air inlet is larger than that of the air outlet.

Preferably, the box body is internally provided with an atomizing device for generating aerosol which is fused with the aerosol for reaction.

Preferably, a drying and purifying mechanism is arranged in the box body.

Preferably, the dry cleaning mechanism is a plurality of grooves which are arranged on the second panel and/or the fourth panel and are internally provided with dry cleaning agents.

Preferably, the top plate, the first panel, the second panel, the third panel and the fourth panel are detachably connected with the frame, and the frame is foldable.

Preferably, sealing gaskets are arranged at the joints of the frame and the top plate, the first panel, the second panel, the third panel and the fourth panel.

Preferably, a first control mechanism for controlling the atomization device and a second control mechanism for simultaneously controlling the air inlet cover and the air outlet cover to open or close are further arranged in the box body; the first control mechanism is electrically connected with the atomization device, and the second control mechanism is electrically connected with the air inlet cover and the air outlet cover; and a first switch electrically connected with the first control mechanism and a second switch electrically connected with the second control mechanism are arranged on the second panel or the fourth panel.

Preferably, the second panel or the fourth panel is provided with at least one threading hole for threading out a line of the control mechanism in the box body, and an elastic rubber sheath is sleeved outside the threading hole.

Compared with the prior art, the beneficial effects of the utility model are that:

(1) the purpose of reducing the use amount of a nucleic acid aerosol removing reagent is achieved by providing a nucleic acid aerosol purifying protective cover with a small space, the cost is reduced, and an experimental environment which is not polluted by the nucleic acid aerosol is provided;

(2) the aerosol filter membrane arranged on the air inlet and the one-way elastic film arranged on the air outlet enable the gas to keep stable flow direction, and the possibility that the air in the nucleic acid aerosol purification protective cover is polluted by the aerosol due to the operation of personnel during the experiment is reduced;

(3) roof, bottom plate, first panel, second panel, third panel, fourth panel all can dismantle with the frame and be connected, and the frame is collapsible, portable transportation.

(4) The application range is wide, and the device can be used on different instruments.

Drawings

FIG. 1 is a schematic structural view of a nucleic acid aerosol purification protective cover according to the present invention;

FIG. 2 is a schematic view of the structure of FIG. 1 with the third panel removed;

FIG. 3 is a schematic view of the structure of FIG. 1 with the top panel and the second panel removed;

FIG. 4 is a schematic view of the structure of FIG. 1 viewed from the rear;

FIG. 5 is an exploded view of the nucleic acid aerosol purification protective cover of the present invention in combination with an experimental apparatus;

the graphic symbols are illustrated as follows:

1. a box body; 2. a frame; 3. a top plate; 4. a first panel; 5. a second panel; 6. a third panel; 7. a fourth panel; 8. a base plate; 9. an air inlet; 91. an aerosol filter membrane; 92. an air inlet cover; 10. an air outlet; 101. a unidirectional elastic film; 102. a vent cover; 11. an atomizing device; 12. a drying and purifying mechanism; 121. a groove; 13. a first switch; 14. a second switch; 15. threading holes; 151. an elastic rubber sheath; 16. an experimental device.

Detailed Description

The present invention will be further described with reference to the following embodiments. Wherein the showings are for the purpose of illustration only and are shown by way of illustration only and not in actual form, and are not to be construed as limiting the present patent; for a better understanding of the embodiments of the present invention, some parts of the drawings may be omitted, enlarged or reduced, and do not represent the size of an actual product; it will be understood by those skilled in the art that certain well-known structures in the drawings and descriptions thereof may be omitted.

The same or similar reference numerals in the drawings of the embodiments of the present invention correspond to the same or similar parts; in the description of the present invention, it should be understood that if there are the terms "upper", "lower", "left", "right", etc. indicating the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, it is only for convenience of description and simplification of the description, but it is not intended to indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and therefore the terms describing the positional relationship in the drawings are only for illustrative purposes and are not to be construed as limitations of the present patent, and those skilled in the art can understand the specific meanings of the terms according to specific situations.

Examples

As shown in fig. 1 to 5, the embodiment of the nucleic acid aerosol purification protection cover of the present invention is an embodiment of a nucleic acid aerosol purification protection cover, wherein the nucleic acid aerosol purification protection cover is a box body 1 provided with a hollow cavity, the box body 1 is provided with a detachable bottom plate 8, the box body 1 is provided with an air inlet 9 and an air outlet 10, the air inlet 9 is covered with an aerosol filter membrane 91, and an air inlet cover 92 is movably provided outside the aerosol filter membrane 91; the edge of the air outlet 10 is provided with a one-way elastic film 101 which enables air to only flow out of the hollow cavity but cannot flow in from the outside of the box body 1, and the middle of the air outlet 10 is provided with a through hole, and the air outlet cover 102 is movably arranged outside the air outlet 10.

As an embodiment of the present invention, the box 1 includes the frame 2, the roof 3 connected with the frame 2, the first panel 4, the second panel 5, the third panel 6, the fourth panel 7 which are connected with the frame 2 and are sequentially arranged, the bottom plate 8 is detachably connected with the frame 2, the air inlet 9 is arranged on the first panel 4, and the air outlet 10 is arranged on the third panel 6 opposite to the first panel 4. The air inlet 9 and the air outlet 10 which are arranged oppositely can shorten the circulation path of air in the box body 1, accelerate ventilation and improve the heat dissipation function. Within the scope of the knowledge of the skilled person, the first panel 4, the second panel 5, the third panel 6, the fourth panel 7 are not specifically indicated, but merely serve to express four side panels of the box.

As an embodiment of the present invention, the cross-sectional area of the air inlet 9 is larger than the cross-sectional area of the air outlet 10. The cross-sectional area of the air inlet 9 is larger than that of the air outlet 10. The cross-sectional area of the air inlet 9 is larger than that of the air outlet 10, so that an air flow flowing from the air inlet 9 to the air outlet 10 is formed, and the heat dissipation effect is improved.

As an embodiment of the present invention, an atomizing device 11 for generating aerosol which is fused with aerosol is provided in the box 1. The atomization device 11 is loaded with a solution which can be fused with the nucleic acid aerosol for generating the aerosol which is fused with the aerosol for achieving the elimination and purification function of the aerosol. The nucleic acid aerosol purification protective cover with the atomizing device 11 can improve convenience, and a reaction device is not required to be additionally provided.

As an embodiment of the present invention, a drying and purifying mechanism 12 is provided in the box body 1. The drying and purifying mechanism 12 is used for drying moisture in the box body 1 and adsorbing redundant nucleic acid aerosol mist, so that a drier and pure environment is kept in the nucleic acid aerosol purification protective cover, and interference on experimental results is reduced.

As an embodiment of the present invention, the drying and purifying mechanism 12 is a plurality of grooves 121 disposed on the second panel 5 and/or the fourth panel 7 and containing a drying and purifying agent therein. Moisture and redundant nucleic acid aerosol mist in the nucleic acid aerosol purification protection cover are eliminated by using the dry purifying agent in the groove 121, a drier and pure environment is kept in the nucleic acid aerosol purification protection cover, and interference on experimental results is reduced. Because the first panel 4 is provided with the air inlet 9, the third panel 6 is provided with the air outlet 10, and the groove 121 is arranged on the second panel 5 and/or the fourth panel 7, the length of the groove 121 can be increased; the arrangement of the groove 121 can enable the dry purifying agent to be embedded into the groove 121 without protruding out of the surface of the panel, so that narrow space in the nucleic acid aerosol purifying protective cover is not occupied completely, and the experiment operation space is not hindered or influenced. It is within the purview of those skilled in the art that the drying bath may be disposed to protrude or the dry sanitizing agent may be directly adhered to the surface of the panel, but that arrangement would take up interior space, but is also possible. Specifically, the dry purifying agent can be a nucleic acid aerosol adsorbing material and activated carbon. The grooves 121 can be arranged in a plurality of strips at different heights, and drying and purifying agents are arranged in the grooves to increase the drying and purifying effects. Due to the arrangement of the air inlet 9 and the air outlet 10, a ventilated environment is formed in the whole box body 1, excessive aerosol scavenger is not needed due to the small space in the box body 1, excessive moisture is not generated, and the arrangement of the grooves 121 and the dry cleaning agent is enough to meet the requirement.

As an embodiment of the present invention, the top plate 3, the first panel 4, the second panel 5, the third panel 6, and the fourth panel 7 are detachably connected to the frame 2, and the frame 2 is foldable. The frame 2 and the face, the first panel 4, the second panel 5, the third panel 6 and the fourth panel 7 can be detachably connected, and the frame 2 can be folded and is convenient to carry and transport. Specifically, the frame 2 may be made into a structure with a through hole therein, the top plate 3, the first panel 4, the second panel 5, the third panel 6, and the fourth panel 7 may be inserted into the through hole of the frame 2 to be connected, or may be made into a structure of a snap connection, and the frame 2, the first panel 4, the second panel 5, the third panel 6, and the fourth panel 7 are respectively provided with a snap and a snap position matched with the snap for detachable connection; the interior of the frame 2 can be connected by hinges or bolts, and can also be made of a material with better toughness, and the material at the position needing to be folded is thinned and is provided with a folding line to facilitate the folding of the frame 2.

As an embodiment of the present invention, the joints between the frame 2 and the top plate 3, the first panel 4, the second panel 5, the third panel 6, and the fourth panel 7 are all provided with a sealing gasket. Seal gasket's setting can promote the leakproofness of whole nucleic acid aerosol purification safety cover, reduces the outside air and gets into from the gap, makes the interior gas of nucleic acid aerosol purification safety cover keep pure, does not polluted by the aerosol, promotes the experiment accuracy.

As an embodiment of the present invention, a first control mechanism for controlling the atomization device 11 and a second control mechanism for simultaneously controlling the opening or closing of the air inlet cover 92 and the air outlet cover 102 are further disposed in the box body 1; the first control mechanism is electrically connected with the atomization device 11, and the second control mechanism is electrically connected with the air inlet cover 92 and the air outlet cover 102; the second panel 5 or the fourth panel 7 is provided with a first switch 13 electrically connected to the first control mechanism and a second switch 14 electrically connected to the second control mechanism. Contain first controller like the singlechip among the first control mechanism, still include the motor, first controller and motor and first switch 13 are connected, through opening first switch 13 before the experiment, first controller transmission signal makes motor drive atomizing device 11, makes the nucleic acid aerosol of liquid clear away reagent turn into aerial fog state and sprays in box 1, reacts with the nucleic acid aerosol in box 1, can close first switch 13 after the purification and make first controller transmission signal close the motor and finally close atomizing device 11. The second control mechanism comprises a second controller, a motor, a first telescopic rod and a second telescopic rod, the second controller is connected with the motor and the second switch 14, and the first telescopic rod is electrically connected with the motor and movably connected with the air inlet cover 92; the second telescopic rod is electrically connected with the motor and movably connected with the air outlet cover 102, the second switch 14 is opened when an experiment is started, and the second controller transmits a signal to the motor to drive the first telescopic rod to drive the air inlet cover 92 to move horizontally, so that the air inlet is opened; simultaneously, the second telescopic rod is driven to drive the exhaust port cover 102 to move horizontally, so that the exhaust port is opened, the ventilation of the nucleic acid aerosol purification protective cover is realized, the second switch 14 is closed in time after the experiment is finished, the air inlet cover 92 and the exhaust port cover 102 are closed in time, and the pollution of aerosol, dust and the like can be isolated. It is within the scope of the skilled person to realize that the second control mechanism may also be of other structures, such as a spring solenoid valve structure implementing an electric pop-up window style or a pneumatic structure.

As an embodiment of the present invention, at least one threading hole 15 for threading out the circuit of the control mechanism in the box is provided on the second panel 5 or the fourth panel 7, and an elastic rubber sheath 151 is provided outside the threading hole 15. Because some control devices exist in the nucleic acid aerosol purification protective cover, such as the atomizing device 11, the first control mechanism, the second control mechanism and the like, the control devices need an external power supply to realize the functions, in order to keep the environment in the whole nucleic acid aerosol purification protective cover from being polluted, the entering of the external air which is not filtered by the aerosol filter membrane 91 needs to be reduced as much as possible, a threading hole 15 needs to be specially arranged, a control line of the control device can pass through the threading hole 15, an elastic rubber sheath 151 sleeved outside the threading hole 15 is used for fixing the control line on one hand, and the control line can be wrapped on the other hand, so that the entering of the external air is reduced as much as possible.

As an embodiment of the present invention, a camera is provided in the box 1, and the camera is electrically connected to the screen of the peripheral device. The condition of experiment operation is convenient for observe clearly in detail from the screen in setting up of camera, reduces the vision in narrow and small space and hinders, promotes experiment accuracy.

As an embodiment of the present invention, the first panel 4, the second panel 5, the third panel 6, the fourth panel 7, and the top plate 3 are transparent and can isolate the aerosol and/or easily dissipate heat. Transparent material is favorable to observing the experiment operation, and the material that can completely cut off the aerosol has further reduced the possibility that the aerosol pollutes from the material, and easy radiating material is favorable to promoting the heat dissipation function, eliminates the heat that produces in the experimentation in time, reduces the influence of narrow and small space temperature rise to the experiment.

The bottom of the nucleic acid aerosol purification protective cover box body 1 is detachable, can be replaced to different instruments for use, is not limited to a PCR instrument, can be customized according to the instrument, is generally larger than the instrument, and is convenient for operation of experimenters.

It is obvious that the above embodiments of the present invention are only examples for clearly illustrating the present invention, and are not limitations to the embodiments of the present invention. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. Any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the claims of the present invention.

Claims (10)

1. A nucleic acid aerosol purification protection cover is characterized in that the nucleic acid aerosol purification protection cover is a box body (1) provided with a hollow cavity, the box body (1) is provided with a detachable bottom plate (8), the box body (1) is provided with an air inlet (9) and an air outlet (10), the air inlet (9) is covered with an aerosol filter membrane (91), and an air inlet cover (92) is movably arranged outside the aerosol filter membrane (91); air exit (10) border is equipped with one-way elastic film (101) that make the air only can flow in but can't flow in from the cavity and be equipped with the through-hole in the middle of box (1) outward, air exit (10) outer activity is equipped with exhaust flap (102).

2. The nucleic acid aerosol purification protective cover according to claim 1, wherein the box body (1) comprises a frame (2), a top plate (3) connected with the frame (2), a first panel (4), a second panel (5), a third panel (6) and a fourth panel (7) which are connected with the frame (2) and are sequentially arranged, the bottom plate (8) is detachably connected with the frame (2), the air inlet (9) is formed in the first panel (4), and the air outlet (10) is formed in the third panel (6) opposite to the first panel (4).

3. The nucleic acid aerosol purification shield of claim 2, wherein the cross-sectional area of the air inlet (9) is greater than the cross-sectional area of the air outlet (10).

4. A nucleic acid aerosol purification shield as claimed in claim 3, wherein the housing (1) is provided with atomising means (11) for generating an aerosol which is in a fused reaction with the aerosol.

5. A nucleic acid aerosol decontamination shield according to claim 3, wherein a dry decontamination mechanism (12) is provided in the housing (1).

6. The nucleic acid aerosol decontamination shroud of claim 5, wherein said dry decontamination mechanism (12) is a plurality of grooves (121) disposed on said second panel (5) and/or said fourth panel (7) and containing dry decontaminant.

7. The nucleic acid aerosol decontamination shroud of claim 2, wherein said top panel (3), first panel (4), second panel (5), third panel (6), fourth panel (7) are each removably attached to said frame (2), said frame (2) being foldable.

8. The nucleic acid aerosol purification shield of claim 2, wherein sealing gaskets are arranged at the joints of the frame (2) and the top plate (3), the first panel (4), the second panel (5), the third panel (6) and the fourth panel (7).

9. The nucleic acid aerosol purification protective cover according to claim 4, wherein a first control mechanism for controlling the atomization device (11), a second control mechanism for simultaneously controlling the air inlet cover (92) and the air outlet cover (102) to be automatically opened or closed are further arranged in the box body (1); the first control mechanism is electrically connected with the atomization device (11), and the second control mechanism is electrically connected with the air inlet cover (92) and the air exhaust cover (102); and a first switch (13) electrically connected with the first control mechanism and a second switch (14) electrically connected with the second control mechanism are arranged on the second panel (5) or the fourth panel (7).

10. The nucleic acid aerosol purification protective cover according to claim 9, wherein at least one threading hole (15) for threading out a line of a control mechanism in the tank body is arranged on the second panel (5) or the fourth panel (7), and an elastic rubber sheath (151) is sleeved outside the threading hole (15).

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