CN213913715U - Reaction device for receiving and transferring fluid sample - Google Patents
Reaction device for receiving and transferring fluid sample Download PDFInfo
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- CN213913715U CN213913715U CN202022725008.8U CN202022725008U CN213913715U CN 213913715 U CN213913715 U CN 213913715U CN 202022725008 U CN202022725008 U CN 202022725008U CN 213913715 U CN213913715 U CN 213913715U
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Abstract
The utility model relates to a reaction device for receiving and transferring fluid samples, which comprises a reaction cavity and a receiving interface, wherein the receiving interface is communicated with the reaction cavity for receiving the fluid samples; the receiving interface comprises a hollow tubular accommodating cavity with an upward opening, a puncturing device, a liquid injection through hole and an exhaust through hole. The hollow tubular holding cavity is used for holding a device for providing a fluid sample, the puncturing device extends upwards from the bottom of the hollow tubular holding cavity by a preset length, one end of the liquid injection through hole is communicated with the hollow tubular holding cavity in a fluid mode, the other end of the liquid injection through hole is communicated with the reaction cavity in a fluid mode, one end of the gas exhaust through hole is communicated with the reaction cavity in a fluid mode, and the other end of the gas exhaust through hole is communicated with the external environment in a fluid mode. The reaction device for receiving and transferring a fluid sample described herein may enable rapid contamination-free receiving and transferring of a fluid sample.
Description
Technical Field
The utility model relates to a chemical industry equipment technical field, concretely relates to reaction unit for receiving and shifting fluid sample.
Background
In addition to the fields of chemical and life engineering, fluid sample analysis is widely used in the diagnostic field of analyzing blood, body fluid taken from a patient for diagnosis, and the like, particularly in the fields of extraction, purification, and detection of nucleic acids.
One key in the method of analyzing a fluid sample is the pre-treatment of the fluid sample. The pretreatment of a fluid sample means that a desired amount of the sample is extracted before the fluid sample is analyzed, and the sample is precisely treated with, for example, a dilution buffer or a lysis solution at an appropriate ratio, or mixed with a reaction reagent in a solid or liquid state, or separated and purified by a packing or a support.
Various sample pretreatment apparatuses have been developed in the art to perform continuous pretreatment of a fluid sample, but when the fluid sample after the pretreatment is transferred to a subsequent reaction apparatus, it is necessary to ensure that the sample is not contaminated as much as possible.
Accordingly, there is a continuing need in the art for the development of a reaction device for receiving and transferring a fluid sample.
SUMMERY OF THE UTILITY MODEL
To address the deficiencies of the prior art, the present application provides a device that can quickly receive and transfer a fluid sample without contamination.
In order to solve the technical problems in the prior art, the present application provides the following technical solutions.
In a first aspect, the present application provides a reaction device for receiving and transferring a fluid sample, characterized by comprising a reaction chamber and a receiving interface, the receiving interface being in fluid communication with the reaction chamber for receiving a fluid sample;
the receiving interface comprises a hollow tubular accommodating cavity with an upward opening, a puncturing device, a liquid injection through hole and an exhaust through hole;
wherein the hollow tubular receiving chamber is for receiving a device for providing a fluid sample;
wherein the piercing means extends upwardly from the bottom of the hollow tubular receiving cavity by a predetermined length;
one end of the liquid injection through hole is in fluid communication with the hollow tubular accommodating cavity, and the other end of the liquid injection through hole is in fluid communication with the reaction cavity;
one end of the exhaust through hole is communicated with the fluid of the reaction cavity, and the other end of the exhaust through hole is communicated with the fluid of the external environment.
In one embodiment of the first aspect, the reaction device for receiving and transferring a fluid sample further comprises a transfer interface disposed at a lower portion of the reaction chamber for outputting a fluid sample.
In one embodiment of the first aspect, the piercing means is a conical member with its tip pointing upwards.
In one embodiment of the first aspect, the conical member tip is hemispherical.
In an embodiment of the first aspect, the liquid injection through hole is disposed at the bottom of the hollow tubular accommodation cavity and is smoothly connected with the bottom of the puncturing device.
In one embodiment of the first aspect, the reaction device for receiving and transferring a fluid sample comprises 3 liquid injection through holes, and the 3 liquid injection through holes are uniformly arranged on the periphery of the bottom of the puncturing device.
In one embodiment of the first aspect, the liquid filling through hole has a sector-shaped cross section, wherein the end with the smaller arc is directed to the bottom of the puncturing device.
In one embodiment of the first aspect, the vent through hole is provided at an outer periphery of the hollow tubular accommodation chamber, and a cross section of the vent through hole is arc-shaped.
In an embodiment of the first aspect, the receiving interface includes 2 vent through holes, and the 2 vent through holes are symmetrically arranged.
In one embodiment of the first aspect, the receiving interface is configured such that when the reaction device for receiving and transferring a fluid sample is used to receive a fluid sample from a device for providing a fluid sample, the device for providing a fluid sample and the hollow tubular receiving cavity are hermetically sealed.
The present application has the advantage over the prior art that the reaction device for receiving and transferring a fluid sample as described herein allows for a fast and contamination-free receiving and transferring of a fluid sample.
Drawings
The present application may be better understood by describing embodiments thereof in conjunction with the accompanying drawings.
Fig. 1 shows a perspective view of a reaction device for receiving and transferring a fluid sample according to an embodiment of the present application.
Fig. 2 shows a back view of a reaction device for receiving and transferring a fluid sample according to an embodiment of the present application.
Fig. 3 shows a right side view of a reaction device for receiving and transferring a fluid sample according to an embodiment of the present application.
Fig. 4 shows a cross-sectional view of a reaction device for receiving and transferring a fluid sample according to an embodiment of the present application.
Fig. 5 shows a cross-sectional view according to plane a-a shown in fig. 2.
FIG. 6 shows a top view of a reaction device for receiving and transferring a fluid sample according to an embodiment of the present application.
The reference numbers illustrate:
100: a reaction device for receiving and transferring a fluid sample;
10: a reaction chamber;
20: a receiving interface;
201: a hollow tubular receiving cavity;
202: a piercing device;
203: a liquid injection through hole;
204: an exhaust through hole;
30: and transferring the interface.
Detailed Description
Unless otherwise defined, technical or scientific terms used herein shall have the ordinary meaning as is understood by those of ordinary skill in the art to which the invention belongs.
All numerical values recited herein as between the lowest value and the highest value are intended to mean all values between the lowest value and the highest value in increments of one unit when there is more than two units difference between the lowest value and the highest value.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are used merely for convenience of description and for simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless otherwise specified.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
The present invention will be described in detail below with reference to the accompanying drawings in conjunction with embodiments. It is noted that in the detailed description of these embodiments, in order to provide a concise description, all features of an actual implementation may not be described in detail.
Referring to fig. 1, the present application provides a reaction device 100 for receiving and transferring a fluid sample, which may include a reaction chamber 10 and a receiving interface 20, the receiving interface 20 being in fluid communication with the reaction chamber 10 for receiving the fluid sample. In this embodiment, in order to fully utilize the self-gravity of the fluid sample and reduce the energy consumption for receiving and transferring the fluid sample, the receiving interface 20 may be disposed above the reaction chamber 10. It will be appreciated by those skilled in the art that the receiving interface 20 may be provided at any other location of the reaction device for receiving and transferring the fluid sample.
In one embodiment, the receiving interface 20 may comprise an upwardly open hollow tubular receiving cavity 201, a piercing device 202, a liquid filling through hole 203 and a vent through hole 204. In one embodiment, the hollow tubular receiving chamber 201 is used to receive a device for providing a fluid sample, such as a pipette and capsule extractor. The device for providing a fluid sample used is not particularly limited in this application, but may generally comprise a fluid sample storage chamber, an outlet in fluid communication with the storage chamber. In one embodiment, the means for providing a fluid sample may comprise a nucleic acid extraction device. In one embodiment, the hollow tubular receiving chamber 201 is adapted to receive an outlet end of a device for providing a fluid sample.
In a preferred embodiment, the hollow tubular receiving cavity 201 of the receiving interface 20 is configured such that when the reaction device for receiving and transferring a fluid sample is used to receive a fluid sample from a device for providing a fluid sample, the device for providing a fluid sample and the hollow tubular receiving cavity 201 are hermetically sealed. In other words, no foreign substances are introduced into the fluid path from the storage chamber of the device for providing a fluid sample to the reaction chamber 10, which ensures rapid contamination-free reception and transfer of the fluid sample.
In this embodiment, the piercing means 202 extends a predetermined length upwards from the bottom of the hollow tubular receiving cavity 201. One end of the liquid injection through hole 203 is in fluid communication with the hollow tubular accommodating cavity 201, and the other end is in fluid communication with the reaction cavity 10. The exhaust vent 204 has one end in fluid communication with the reaction chamber 10 and one end in fluid communication with the external environment. It will be appreciated by those skilled in the art that the device for providing a fluid sample is typically sealed by a sealing member, such as a sealing membrane, when the fluid sample is not being output. Accordingly, the piercing means 202 is used to pierce the seal and allow the fluid sample to flow into the reaction chamber 10 through the liquid injection through hole 203. The gas in the reaction chamber 10 can be exhausted to the atmosphere by the exhaust through hole 204, so that the gas pressure in the reaction chamber 10 is maintained at an atmospheric pressure, and the fluid sample can be smoothly injected into the reaction chamber 10 through the liquid injection through hole 203.
In one embodiment, in order to achieve efficient and automated transfer of the fluid sample flowing into the reaction chamber 10, the reaction device 100 for receiving and transferring the fluid sample may further include a transfer interface 30. In one embodiment, the transfer interface 30 may be disposed at a lower portion of the reaction chamber 10 for outputting a fluid sample.
In one embodiment, the piercing device 202 is a conical member with its tip pointing upward. In one embodiment, to provide the required strength, the tip of the conical member is hemispherical.
In one embodiment, the liquid injection through hole 203 is disposed at the bottom of the hollow tubular accommodating cavity 201 and is smoothly connected with the bottom of the puncturing device 202. In a specific embodiment, the reaction device 100 for receiving and transferring a fluid sample may include 3 liquid injection through holes 203, and the 3 liquid injection through holes 203 are uniformly disposed on the periphery of the bottom of the puncturing device. In a preferred embodiment, the liquid injection through hole 203 has a sector-shaped cross section, wherein the end with the smaller arc is toward the bottom of the puncturing device.
In one embodiment, the vent through hole 204 is disposed at the periphery of the hollow tubular receiving cavity 201, and the cross section of the vent through hole 204 is arc-shaped. In one embodiment, the receiving interface 10 may include 2 vent through holes 204, and the 2 vent through holes 204 are symmetrically disposed.
The above-mentioned embodiments, further detailed description of the objects, technical solutions and advantages of the present invention, it should be understood that the above-mentioned embodiments are only specific embodiments of the present invention, and are not intended to limit the present invention, and any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the scope of the present invention.
Claims (10)
1. A reaction device for receiving and transferring a fluid sample, comprising a reaction chamber and a receiving interface in fluid communication with the reaction chamber for receiving a fluid sample;
the receiving interface comprises a hollow tubular accommodating cavity with an upward opening, a puncturing device, a liquid injection through hole and an exhaust through hole;
wherein the hollow tubular receiving chamber is for receiving a device for providing a fluid sample;
wherein the piercing means extends upwardly from the bottom of the hollow tubular receiving cavity by a predetermined length;
one end of the liquid injection through hole is in fluid communication with the hollow tubular accommodating cavity, and the other end of the liquid injection through hole is in fluid communication with the reaction cavity;
one end of the exhaust through hole is communicated with the fluid of the reaction cavity, and the other end of the exhaust through hole is communicated with the fluid of the external environment.
2. The reaction device for receiving and transferring a fluid sample according to claim 1, wherein the reaction device for receiving and transferring a fluid sample further comprises a transfer port disposed at a lower portion of the reaction chamber for outputting a fluid sample.
3. A reaction device for receiving and transferring a fluid sample according to claim 1 or 2, wherein the piercing means is a conical member with the tip pointing upwards.
4. A reaction device for receiving and transferring a fluid sample according to claim 3, wherein the tip of the conical member is hemispherical.
5. A reaction device for receiving and transferring a fluid sample according to claim 1 or 2, wherein the liquid injection through hole is provided at the bottom of the hollow tubular receiving chamber and is smoothly connected with the bottom of the piercing means.
6. The reaction device for receiving and transferring a fluid sample according to claim 5, wherein the reaction device for receiving and transferring a fluid sample comprises 3 liquid injection through holes, and the 3 liquid injection through holes are uniformly arranged on the periphery of the bottom of the puncturing device.
7. The reaction device for receiving and transferring a fluid sample of claim 5, wherein the fluid filling through hole has a sector-shaped cross section with a smaller arc end facing the bottom of the piercing device.
8. The reaction device for receiving and transferring a fluid sample according to claim 1 or 2, wherein the vent through hole is provided at an outer periphery of the hollow tubular accommodation chamber, and a cross section of the vent through hole is arc-shaped.
9. The reaction device for receiving and transferring a fluid sample according to claim 8, wherein the receiving interface comprises 2 venting through holes, and the 2 venting through holes are symmetrically arranged.
10. The reaction device for receiving and transferring a fluid sample according to claim 1, wherein the receiving interface is configured such that when the reaction device for receiving and transferring a fluid sample is used to receive a fluid sample from a device for providing a fluid sample, the device for providing a fluid sample and the hollow tubular receiving cavity are hermetically sealed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022725008.8U CN213913715U (en) | 2020-11-23 | 2020-11-23 | Reaction device for receiving and transferring fluid sample |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022725008.8U CN213913715U (en) | 2020-11-23 | 2020-11-23 | Reaction device for receiving and transferring fluid sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213913715U true CN213913715U (en) | 2021-08-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022725008.8U Active CN213913715U (en) | 2020-11-23 | 2020-11-23 | Reaction device for receiving and transferring fluid sample |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213913715U (en) |
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- 2020-11-23 CN CN202022725008.8U patent/CN213913715U/en active Active
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