CN213758740U - Rat esophagus drug delivery system - Google Patents

Abstract

The utility model discloses a rat esophagus delivery system, including the syringe, the syringe is equipped with cylinder, propeller, syringe cylinder front end be equipped with but plug hose, the syringe be equipped with the seal wire that runs through the propeller and extend to but plug hose front end, seal wire middle part be equipped with the plug, the plug can not wear out the propeller, but plug hose be silicone tube or polyurethane pipe, but plug hose lateral surface on be equipped with the scale sign, the syringe be equipped with Y type and connect, Y type connect one end connect cylinder front end, one end connect but plug hose, one end pass through collector tube connection collector bottle, collector bottle and vacuum pump pipeline intercommunication, the collector tube on be equipped with adjustable pressing gear. The utility model discloses it is internal to guarantee that the medicine reachs the rat, can not cause very big injury, and simple structure is reliable for the rat.

Description

Rat esophagus drug delivery system

Technical Field

The utility model relates to a medical treatment experimental facilities technical field specifically is a rat esophagus delivery system.

Background

In experimental animals, rats are widely applied to scientific experiments due to low price, quick breeding and easy feeding, but the drug administration process in former rat modeling is not satisfactory, or the rats are easy to be disabled or even die due to rough puncture drug administration operation; or, when the drug is orally administered, part of the drug does not reach the body of the rat due to the habit of spitting out saliva and the like in the rat, and the actual drug intake dose cannot be judged.

SUMMERY OF THE UTILITY MODEL

The defect to prior art has, the utility model provides a can guarantee that the medicine reachs the rat internal, can not cause great injury for the rat, the rat esophagus drug delivery system of simple structure easy operation.

In order to achieve the above object, the utility model provides a following technical scheme:

the utility model provides a rat esophagus drug delivery system, includes the syringe, the syringe is equipped with cylinder, propeller, syringe cylinder front end be equipped with the plug hose, the syringe be equipped with and run through the propeller and extend to the seal wire in the plug hose, seal wire middle part be equipped with the plug, the plug can not wear out the propeller. The syringe of this scheme is disposable PVC syringe, the syringe cylinder, the propeller cavity, the propeller front end is the silica gel material, ensure closely to wrap up the seal wire, make its syringe inner chamber remain airtight state all the time, it passes to have the seal wire in the syringe, direct hose front end, the seal wire is used for increasing hose strength, the intubate of being convenient for, the subsidiary silica gel plug of seal wire middle-end (the seal wire can pass the propeller, the plug is bigger, can not wear out the propeller, can plug up the aperture that the seal wire passed propeller top inner wall department as the end cap during administration), after syringe front end hose inserts the rat esophagus, extract the seal wire, when pulling out the silica gel plug on the seal wire and blocking syringe propeller top inner wall, the syringe passageway of dosing is open, then promote the syringe propeller to dose, the end of dosing is extracted the hose.

Preferably, the pluggable hose is a silicone tube or a polyurethane tube, and the outer side surface of the pluggable hose is provided with scale marks. The pluggable hose of the scheme is a soft silica gel/polyurethane pipe, scales are arranged on the pluggable hose, the entering depth of the hose can be known, the hose can slide along the esophagus of a rat in a bending mode, and the rat can be prevented from being greatly injured.

Preferably, the syringe be equipped with the Y type and connect, Y type connect one end connect the cylinder front end, but one end connection plug hose, one end passes through the collector tube and connects the collector bottle, the collector bottle communicate with the vacuum pump pipeline. This scheme still can be used to for the rat gastric lavage, but the syringe is connected the plug hose earlier and is put the pipe for the rat, breaks away from the plug hose after success, but plug hose connection Y type connects, and Y type connects an interface of forked end meets the syringe, sends into clean warm water, and another interface connection collecting bottle can collect the gastric juice of washing out and carry out the analysis, another interface connection negative pressure suction apparatus (vacuum pump) of collecting bottle.

Preferably, the liquid collecting pipe is provided with an adjustable pressing gear. Liquid flow in the adjustable collecting tube of gear is pressed in this scheme is adjustable, avoids the too big injury to rat stomach of negative pressure, influences gastric juice composition analysis's accuracy.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the front end of the drug delivery system adopts a hose, so that the damage to the oral cavity and the esophageal mucosa of a rat is reduced, the tolerance is good, and the stress and death of the rat in an experiment are reduced;

2. adopt and to dismantle the subassembly, convenient corresponding part of free collocation to realize diversified diagnosis and treat the function.

Drawings

Fig. 1 is a schematic structural diagram of the syringe of the present invention.

Fig. 2 is a schematic structural diagram of the present invention.

In the figure: 1. injector 2, needle cylinder 3, propeller 4 and pluggable hose

5. Guide wire 6, Y-shaped connector 7, liquid collecting pipe 8 and liquid collecting bottle

9. Vacuum pump 10, adjustable pressing gear.

Detailed Description

The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, rather than all embodiments, and all other embodiments obtained by a person of ordinary skill in the art without creative work belong to the protection scope of the present invention based on the embodiments of the present invention.

Referring to fig. 1-2, the present invention provides the following technical solutions:

embodiment 1, as shown in fig. 1, a rat esophageal drug delivery system includes an injector 1, the injector 1 is provided with a syringe 2 and a propeller 3, the front end of the syringe 2 of the injector 1 is provided with a pluggable hose 4, the injector 1 is provided with a guide wire 5 penetrating through the propeller 3 and extending into the pluggable hose 4, the middle part of the guide wire 5 is provided with a rubber plug, and the rubber plug cannot penetrate through the propeller 3; the pluggable hose 4 is a silicone tube or a polyurethane tube, and scale marks are arranged on the outer side face of the pluggable hose 4.

In embodiment 2, as shown in fig. 2, the injector 1 is the same as that in embodiment 1, the injector 1 is provided with a Y-shaped joint 6, one end of the Y-shaped joint 6 is connected with the front end of the needle cylinder 2, the other end is connected with the pluggable hose 4, the other end is connected with a liquid collecting bottle 8 through a liquid collecting pipe 7, and the liquid collecting bottle 8 is communicated with a vacuum pump 9 through a pipeline; the liquid collecting pipe 8 is provided with an adjustable pressing gear 10.

The specific implementation process is as follows:

embodiment 1, utilize the seal wire 5, insert the rat esophagus with pluggable hose 4, have the scale above the pluggable hose 4, can know that pluggable hose 4 gets into the rat esophagus degree of depth, and pluggable hose 4 can slide along the rat esophagus is crooked, after pluggable hose 4 inserts the rat esophagus and arrives the regulation degree of depth, outwards extract seal wire 5, when pulling out the 3 top inner walls of 1 propeller of syringe 1 of silica gel on the seal wire 5 up to, syringe 1 passageway of dosing is open, then promote 1 propeller 3 of syringe and dose, the end of dosing is extracted pluggable hose 4.

In the embodiment 2, the front-section operation is the same as that in the embodiment 1, the injector 1 uses the pluggable hose 4 to place a tube for a rat, the injector 1 and the pluggable hose 4 are disconnected after success, the pluggable hose 4 is connected with a Y-shaped connector 6, one interface at the forked end of the Y-shaped connector 6 is connected with the injector 1, the injector 1 can send clean warm water into the esophagus of the rat, the other interface is connected with a liquid collecting bottle 8 through a liquid collecting tube 7, gastric juice washed out of the rat can be collected for analysis, and the other interface of the liquid collecting bottle 8 is connected with a vacuum pump 9; the flow rate of the liquid in the liquid collecting pipe 7 can be adjusted by using the adjusting pressing gear 10.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (4)

1. The utility model provides a rat esophagus delivery system, includes the syringe, and the syringe is equipped with cylinder, propeller, its characterized in that: the utility model discloses a but syringe needle cylinder front end be equipped with the plug hose, the syringe be equipped with and run through the propeller and extend to the seal wire in the plug hose, seal wire middle part be equipped with the plug, the plug can not wear out the propeller.

2. The esophageal delivery system for rats of claim 1, wherein: the pluggable hose is a silicone tube or a polyurethane tube, and scale marks are arranged on the outer side face of the pluggable hose.

3. The esophageal delivery system for rats of claim 1, wherein: the syringe be equipped with Y type and connect, Y type connect one end connect the cylinder front end, but one end connection plug hose, one end passes through the collector tube and connects the collecting bottle, the collecting bottle communicate with the vacuum pump pipeline.

4. The esophageal delivery system for rats of claim 3, wherein: the liquid collecting pipe is provided with an adjustable pressing gear.

Images