CN213669887U

CN213669887U - Platelet collection device

Info

Publication number: CN213669887U
Application number: CN202021923205.4U
Authority: CN
Inventors: 路志浩; 张敏; 巩家富; 薛兆雷; 刘君鹏; 田召学
Original assignee: Shandong Zhongbaokang Medical Devices Co ltd
Current assignee: Shandong Zhongbaokang Medical Devices Co ltd
Priority date: 2020-09-07
Filing date: 2020-09-07
Publication date: 2021-07-13
Anticipated expiration: 2030-09-07

Abstract

The utility model belongs to the technical field of blood collection, concretely relates to platelet collection device, including control box and inside whole blood pump, the centrifugal pump, the circulating pump, the PRP pump, the plasma pump, the anticoagulant pump, four passways of whole blood pump connect the centrifugal pump respectively, plasma pump and red blood cell bag, the passway of centrifugal pump still connects the separation bag, the circulating pump, whole blood bag of keeping in, the passway of PRP pump still connects the separation bag, collect the bag, the circulating pump, the collection bag and the plasma bag are connected to the plasma pump, the whole blood pump connects blood taking needle and normal saline bag through sharing the pipeline, the whole blood pump connects the blood taking needle; in the control box, all be provided with the switch between pump and the pump, between pump and the blood taking needle, between pump and the bag, six pumps of arranging in the control box of this application are used for the platelet to gather, by the circulation of switch control liquid stream, the pump drives the liquid stream and flows, the operation of being convenient for, simultaneously, adopts the dual function of centrifugal pump and centrifugal bucket for blood separation is more accurate, and each composition of blood also can more reasonable utilization.

Description

Platelet collection device

Technical Field

The application belongs to the technical field of blood collection, concretely relates to platelet collection system.

Background

The statements in this section merely provide background information related to the present disclosure and may not necessarily constitute prior art.

At present, the blood station collects blood platelets mostly by using a machine apheresis mode, and the apheresis principle is based on a centrifugal method. Blood is through the centrifugation in the bag, and red blood cell, leucocyte, platelet, plasma can be separated because the density difference to realize the collection of specific composition, the scheme of current collection platelet adopts the control box more, and manufacturing cost is high and the function is few, only relies on the centrifugal pump centrifugation in the control box, and the purity of platelet collection is not high, and blood utilization is also unreasonable, and in addition, the control box is more, and control is complicated, and the error rate is high.

SUMMERY OF THE UTILITY MODEL

In order to solve the above problems, the present application provides a platelet collecting device.

The utility model aims at providing a platelet collection system, the device have the blood sampling, return blood, return defeated, the defeated, red blood cell concentration of defeated function such as dilute to through the quantity that reduces the control box, arrange the flow of liquid in pump and the pump, reduced work load and error rate, improved the work efficiency that the staff collected the platelet.

In order to achieve the purpose, the following technical scheme is adopted in the application:

a platelet collection device comprises a monitoring box, wherein a full blood pump, a centrifugal pump, a circulating pump, a PRP pump, a plasma pump and an anticoagulant pump are arranged in the monitoring box, the full blood pump, the centrifugal pump, the PRP pump and the plasma pump are respectively provided with at least four channel ports, the circulating pump and the anticoagulant pump are respectively provided with at least two channel ports, the four channel ports of the full blood pump are respectively connected with the centrifugal pump, the plasma pump and a red blood cell bag, the channel ports of the centrifugal pump are also connected with a separation bag, the circulating pump and a whole blood temporary storage bag, the channel ports of the PRP pump are also connected with the separation bag, a collection bag and the circulating pump, the plasma pump is connected with the collection bag and the blood plasma bag, the whole blood pump is connected with a blood taking needle and a physiological; in the monitoring box, switches are arranged between the pumps, between the pumps and the blood taking needles and between the pumps and the bags.

Furthermore, the erythrocyte bag is also connected with a separation bag, and a switch is arranged on a pipeline between the erythrocyte bag and the separation bag.

Further, the switch comprises a clamp and a valve, and the change of the flow direction of the liquid flow is realized by opening the switch.

Furthermore, the anticoagulant pump is connected with the whole blood pump and the anticoagulant bag.

Further, the PRP pump is connected to a platelet storage bag.

Furthermore, the whole blood pump, the centrifugal pump, the circulating pump, the PRP pump, the blood pump and the anticoagulant pump are distributed in the monitoring box in a counterclockwise way.

Furthermore, the collecting bag and the separating bag are connected into a whole to form the centrifugal bag.

Further, this application still includes the centrifugation bucket, and the centrifugation bucket setting is outside monitoring the box, when needing the centrifugation, will collect bag or centrifugation bag and put into the centrifugation bucket, is used for collecting the centrifugal layering of bag or the interior liquid of centrifugation bag by the centrifugation bucket.

Compared with the prior art, the beneficial effect of this application is:

1. this application arranges six pumps in the control box and is used for the platelet to gather, by the circulation of switch control liquid stream, the pump drives the liquid stream and flows, the operation of being convenient for, simultaneously, adopts the dual function of centrifugal pump and centrifugation bucket for blood separation is more accurate, and each composition of blood also can more reasonable utilization.

2. This application adopts a control box control liquid stream, has reduced the use of control box and has realized functions such as blood sampling, return the blood, return defeated, the defeated of transfer, red blood cell concentration dilution, to enterprise's production, this kind of device can reduce cost, improve production efficiency, promotion profit, to the user, installation, the convenient to use of this kind of single control box has reduced work load and error rate, has improved the work efficiency that the staff gathered the platelet.

3. The monitoring box is only provided with one blood taking needle, and the single-needle continuous centrifugal bag type secondary centrifugation method for single blood taking of platelets has more advantages, and firstly, the single needle is used for pricking only one needle for a blood donor or a blood bag, so that the monitoring box is more friendly; secondly, continuous type, all can carry out centrifugal separation platelet when drawing blood and returning blood, it is more high-efficient, and thirdly, the platelet of this application collection can add the pureness.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this application, illustrate embodiments of the application and, together with the description, serve to explain the application and are not intended to limit the application.

Fig. 1 is a schematic view of the overall structure of the monitoring box of the present application.

Fig. 2 is a schematic diagram of the overall structure of a platelet collection device according to the present application.

FIG. 3 is a fluid flow diagram of the blood collection process of the present application.

Fig. 4 is a fluid flow diagram of the blood return process of the present application.

Fig. 5 is a flow chart of step 1 during the transfer process of the present application.

Fig. 6 is a flow chart of step 3 during the transfer process of the present application.

The blood collection and control system comprises a blood pump 1, a whole blood pump 2, a centrifugal pump 3, a circulating pump 4, a PRP pump 5, a blood pump 6, an anticoagulant pump 7, a first valve 8, a second valve 9, a third valve 10, a fourth valve 11, a fifth valve 12, a saline clamp 13, a blood return clamp 14, a blood inlet clamp 15, an anticoagulant clamp 16, a red blood cell bag 17, a whole blood temporary storage bag 18, a physiological saline bag 19, an anticoagulant bag 20, a blood plasma bag 21, a platelet storage bag 22, a separation bag 23, a collection bag 24, a PRP clamp 25, a blood collection needle 26 and a monitoring box.

30. A first pipe, 31, a second pipe, 32, a third pipe, 33, a fourth pipe, 34, a fifth pipe, 35, a sixth pipe, 36, a seventh pipe, 37, an eighth pipe, 38, a ninth pipe, 39, a tenth pipe, 40, an eleventh pipe, 41, a twelfth pipe, 42, a thirteenth pipe, 43, a fourteenth pipe, 44, a fifteenth pipe, 45, a sixteenth pipe, 46, a seventeenth pipe.

1.1, a first channel port of a whole blood pump, 1.2, a second channel port of the whole blood pump, 1.3, a third channel port of the whole blood pump, 1.4 and a fourth channel port of the whole blood pump; 2.1, a first channel port of the centrifugal pump, 2.2, a second channel port of the centrifugal pump, 2.3, a third channel port of the centrifugal pump, 2.4, a fourth channel port of the centrifugal pump, 3.1, a first channel port of the circulating pump, 3.2, a second channel port of the circulating pump, 4.1, a first channel port of the PRP pump, 4.2, a second channel port of the PRP pump, 4.3, a third channel port of the PRP pump, 4.4, a fourth channel port of the PRP pump, 5.1, a first channel port of the blood plasma pump, 5.2, a second channel port of the blood plasma pump, 5.3, a third channel port of the blood plasma pump, 5.4, a fourth channel port of the blood plasma pump, 6.1, a first channel port of the anticoagulant pump, 6.2 and a second channel port of the anticoagulant pump.

The specific implementation mode is as follows:

the present application will be further described with reference to the following drawings and examples.

It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments according to the present disclosure. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, and it should be understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof, unless the context clearly indicates otherwise.

In the present disclosure, terms such as "upper", "lower", "left", "right", "front", "rear", "vertical", "horizontal", "side", "bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only relational terms determined for convenience in describing structural relationships of the parts or elements of the present disclosure, and do not refer to any parts or elements of the present disclosure, and are not to be construed as limiting the present disclosure.

Example 1

The utility model provides a platelet collection system, adopt single needle to gather the platelet, including control box 26, be provided with 6 pumps in the control box 26, be whole blood pump 1 respectively, centrifugal pump 2, circulating pump 3, PRP pump 4, blood pulp pump 5, anticoagulant pump 6, in this embodiment, whole blood pump 1, centrifugal pump 2, circulating pump 3, PRP pump 4, blood pulp pump 5, anticoagulant pump 6 is anticlockwise distribution at control box 26, be provided with red blood cell bag 16 in the outside of control box 26, bag 17 is kept in to whole blood, normal saline bag 18, anticoagulant bag 19, blood pulp bag 20, platelet is preserved bag 21, separation bag 22, collect bag 23, in this embodiment, collect bag 23 and separation bag 22 and put together, belong to an integral part, for the centrifugation bag.

Wherein, the whole blood pump 1, the centrifugal pump 2, the PRP pump 4 and the blood pump 5 are provided with four channel ports, the circulating pump 3 and the anticoagulant pump 6 are provided with two channel ports, specifically, the four channel ports of the whole blood pump 1 are a first channel port 1.1 of the whole blood pump, a second channel port 1.2 of the whole blood pump, a third channel port 1.3 of the whole blood pump and a fourth channel port 1.4 of the whole blood pump, when the six pumps are arranged anticlockwise, the first channel port 1.1 of the whole blood pump, the second channel port 1.2 of the whole blood pump, the third channel port 1.3 of the whole blood pump and the fourth channel port 1.4 of the whole blood pump are also arranged anticlockwise, similarly, the four channel ports of the centrifugal pump 2 comprise a first channel port 2.1 of the centrifugal pump, a second channel port 2.2 of the centrifugal pump, a third channel port 2.3 of the centrifugal pump and a fourth channel port 2.4 of the centrifugal pump which are also arranged anticlockwise, the four channel ports of the PRP pump 4 comprise a first channel port 4.1 of the PRP pump, the PRP pump third port 4.3 and the PRP pump fourth port 4.4 are also arranged anticlockwise, four ports of the blood slurry pump 5, including a blood slurry pump first port 5.1, a blood slurry pump second port 5.2, a blood slurry pump third port 5.3 and a blood slurry pump fourth port 5.4 are also arranged anticlockwise, the circulating pump 3 is provided with two ports, namely a circulating pump first port 3.1 and a circulating pump second port 3.2, the circulating pump first port 3.1 is close to the centrifugal pump 2, the circulating pump second port 3.2 is close to the PRP pump 4, the anticoagulant pump 6 is provided with two ports, namely an anticoagulant pump first port 6.1 and an anticoagulant pump second port 6.2, the anticoagulant pump first port 6.1 is close to the blood slurry pump 5, and the anticoagulant pump second port 6.2 is close to the whole blood pump 1.

The first channel port 1.1 of the whole blood pump is connected with a blood taking needle 25 through a first pipeline 30, a blood inlet clamp 14 is arranged on the first pipeline 30, the second channel port 1.2 of the whole blood pump is connected with a second pipeline 31, two branch ports are arranged on the second pipeline 31, the two branch ports of the second pipeline 31 are respectively connected with a physiological saline bag 18 and the blood taking needle 25, a saline clamp 12 is arranged on the pipeline of the second pipeline 31 connected with the physiological saline bag 18, a blood return clamp 13 is arranged on the pipeline of the second pipeline 31 connected with the blood taking needle 25, the third channel port 1.3 of the whole blood pump is connected with a third pipeline 32, the third pipeline 32 is connected with a red blood cell bag 16, a first valve 7 is arranged on the third pipeline 32, the circulation or the disconnection of the liquid flow between the red blood cell bag 16 and the whole blood pump 1 is further controlled by controlling the first valve 7, the fourth channel port 1.4 of the whole blood pump is connected with a fourth pipeline 33, and two, two branch openings of a fourth pipeline 33 are respectively connected with a first channel opening 2.1 of the centrifugal pump and a first channel opening 5.1 of the plasma pump, a second valve 8 is arranged on the pipeline of the fourth pipeline 33 connected with the first channel opening 2.1 of the centrifugal pump, the circulation or disconnection of liquid flow between the whole blood pump 1 and the centrifugal pump 2 is controlled through the second valve 8, a third valve 9 is arranged on the pipeline of the fourth pipeline 33 connected with the first channel opening 5.1 of the plasma pump, and the circulation or disconnection of the liquid flow between the whole blood pump 1 and the centrifugal pump 2 is controlled through the third valve 9.

The second channel port 2.2 of the centrifugal pump is connected with the whole blood temporary storage bag 17 through a fifth pipeline 34, the third channel port 2.3 of the centrifugal pump is connected with the separation bag 22 through a sixth pipeline 35, the separation bag 22 comprises three channel ports which are respectively an upper channel port of the separation bag 22, a middle channel port of the separation bag 22 and a lower channel port of the separation bag 22, the sixth pipeline 35 is connected with the middle channel port of the separation bag 22, the lower channel port of the separation bag 22 is connected with the red blood cell bag 16 through a seventh pipeline 36, the upper channel port of the separation bag 22 is connected with a third channel port 4.3 of the PRP pump through an eighth pipeline 37, the eighth pipeline 37 is provided with a PRP clamp 24, the PRP clamp 24 can also be replaced by a valve, and the fourth channel port 2.4 of the centrifugal pump is connected with the first channel port 3.1 of the circulating pump.

The second channel port 3.2 of the circulating pump is connected with the first channel port 4.1 of the PRP pump through a tenth pipeline 39, the second channel port 4.2 of the PRP pump is connected with the collection bag 23 through an eleventh pipeline 40, the collection bag 23 comprises two channel ports which are respectively a channel port on the upper layer of the collection bag 23 and a channel port on the lower layer of the collection bag 23, the second channel port 4.2 of the PRP pump is connected with the channel port on the upper layer of the collection bag 23 through the eleventh pipeline 40, the fourth channel port 4.4 of the PRP pump is connected with the platelet preservation bag 21 through a twelfth pipeline 41, the twelfth pipeline 41 is provided with a fourth valve 10, and the fourth valve 10 controls the flow of the liquid between the PRP pump 4 and the platelet preservation bag 21 to be communicated or disconnected.

The second port 5.2 of the blood pump is connected with a lower-layer port of the collection bag 23 through a thirteenth pipeline 42, the third port 5.3 of the blood pump is connected with the blood bag 20 through a fourteenth pipeline 43, the fourth port 5.4 of the blood pump is connected with a fourth pipeline 33, concretely, the fourth port is connected with the fourth pipeline 33 through a fifteenth pipeline 44, the fourth pipeline 33 is connected with the fifteenth pipeline 44 through a branch port which is separated from the pipeline of the blood pump, and the fifteenth pipeline 44 is provided with a fifth valve 11.

Anticoagulant pump first access port 6.1 connects anticoagulant bag 19 through sixteenth pipeline 45, and anticoagulant pump second access port 6.2 connects first pipeline 30 through seventeenth pipeline 46, is provided with anticoagulant on the seventeenth pipeline 46 and presss from both sides 15.

It should be noted that the upper passage port of the separation bag 22, the middle passage port of the separation bag 22, the lower passage port of the separation bag 22, the upper passage port of the collection bag 23, and the lower passage port of the collection bag 23 are only names in this application, and do not represent specific positions of the passage ports on the separation bag 22 or the collection bag 23, and the connection of the tube, pump, or blood bag with the respective passage ports of the separation bag 22 and the collection bag 23 is used as the flow component flowing out from the respective passage ports.

Example 2

The application discloses a platelet collecting method for separating platelets from collected whole blood bags, which adopts a platelet collecting device disclosed in embodiment 1 of the present application, blood in the whole blood bag is obtained after a person has taken a blood sample, the blood is not in the body of the living body but in the whole blood bag, a blood taking needle 25 is inserted into the whole blood bag, then, in the first step, blood is taken, during the blood taking process, a whole blood pump 1 and an anticoagulant pump 6 are started, a blood inlet clamp 14 is opened, the blood and the anticoagulant in the whole blood bag are mixed and then enter the whole blood pump 1 from a first passage port 1.1 of the whole blood pump along a first pipeline 30, a third valve 9 is closed, the blood and the anticoagulant are enabled to reach a first passage port 2.1 of the centrifugal pump along a fourth pipeline 33 and enter the centrifugal pump 2, the centrifugal pump 2 is started, the blood and anticoagulant in the centrifugal pump 2 are divided into two parts, a half of the mixed liquid flow enters a temporary storage bag 17 through a second passage 2.2 and a fifth pipeline 34 of the centrifugal pump, the other half of the mixed liquid flow passes through the third port 2.3 of the centrifugal pump and enters the separation bag 22 along the middle port of the sixth tube 35 and the separation bag 22, and under the centrifugal action of the centrifugal pump 2, the blood in the separation bag 22 is layered, so that the blood is separated into upper layer plasma and lower layer high concentration red cell liquid, the platelets are in the plasma, the lower layer high concentration red cell liquid enters the first tube 30 along the lower port of the separation bag 22 and finally enters the red cell bag 16 for preservation, the PRP pump 4 is started and the PRP clamp 24 is opened, the fourth valve 10 is closed, the plasma in the separation bag 22 enters the eighth tube 37 along the upper port of the separation bag 22 and enters the third port 4.3 of the PRP pump along the eighth tube 37 and enters the PRP pump 4, the plasma in the PRP pump 4 enters the collection bag 23 along the second port 4.2 of the PRP pump, the eleventh tube 40 and the upper port of the collection bag 23, preferably, the collection bag 23 can be placed in a centrifuge bucket for separation, so that the plasma and platelets are separated, the plasma pump 5 is started, so that the plasma enters the thirteenth pipeline 42 along the lower passage port of the collection bag 23, enters the plasma pump 5 along the second passage port 5.2 of the plasma pump, and the plasma in the plasma pump 5 enters the fourteenth pipeline 43 along the first passage port 5.1 of the plasma pump, the fifteenth pipeline 44 of the plasma pump, the fourth passage port 5.4 of the plasma pump, the third passage port 5.3 of the plasma pump, and finally enters the plasma bag 20, while the platelets in the plasma remain in the collection bag 23.

In the second step, blood returning is performed, the blood in the whole blood temporary storage bag 17 enters the centrifugal pump along the fifth pipeline 34 and the second passage port 2.2 of the centrifugal pump, and enters the separation bag 22 from the third passage port 2.3 of the centrifugal pump along the sixth pipeline 35 and the middle passage port of the separation bag 22, the blood is centrifugally separated into plasma at the upper layer and high-concentration blood cell liquid at the lower layer in the separation bag 22, the high-concentration blood cell liquid at the lower layer enters the first pipeline 30 along the lower passage port of the separation bag 22 and finally enters the red blood cell bag 16 for preservation, the plasma in the separation bag 22 enters the eighth pipeline 37 along the upper passage port of the separation bag 22 and enters the third passage port 4.3 of the PRP pump along the eighth pipeline 37 and enters the PRP pump 4, the plasma in the PRP pump 4 enters the collection bag 23 along the second passage port 4.2 of the PRP pump, the eleventh pipeline 40 and the upper passage port of the collection bag 23, and the collection bag 23 can be placed in a barrel for centrifugal separation as a preference, the plasma and the platelets are layered, the plasma pump 5 is started, the plasma enters the thirteenth pipeline 42 along the lower passage port of the collection bag 23, enters the plasma pump 5 along the second passage port 5.2 of the plasma pump, the plasma in the plasma bag 20 enters the plasma pump along the fourteenth pipeline 43 and the third port 5.3 of the plasma pump, under the action of the inversion of the plasma pump, the plasma enters the whole blood pump 1 from the first channel port 5.1 of the plasma pump along the fourth pipeline 33 and the fourth channel port 1.4 of the whole blood pump, the inversion of the whole blood pump 1 also enables the high-concentration red cell liquid in the red cell bag 16 to enter the whole blood pump 1 along the third pipeline 32 and the third channel port 1.3 of the whole blood pump, so that the plasma and the high-concentration red blood cell liquid in the whole blood pump 1 are mixed and the blood enters the blood bag along the whole blood pump second passage 1.2, the second pipeline 31 and the blood collection needle 25, and the platelet liquid is stored in the collection bag 23.

Blood sampling and blood returning operations are performed for multiple times, so that the volume of platelet liquid in the collection bag 23 is increased continuously, a large amount of platelet liquid is stored in the collection bag 23, the platelet liquid is a combination of a large amount of platelets and a small amount or a small amount of plasma, the collection bag 23 is put into a centrifugal barrel as a part of a centrifugal bag, after the centrifugation process is finished, the centrifugal bag is taken out of the centrifugal barrel, the centrifugal barrel can adopt an existing centrifugal processing device, wherein a processing chamber rotates along with the driving of an umbilical cord section, for example, the centrifugal processing device mentioned in the patent US4120449A starts a plasma pump 5, the plasma in the collection bag 23 enters a thirteenth pipeline 42 along a lower-layer channel opening of the collection bag 23 and enters the plasma pump 5 along a second channel opening 5.2 of the plasma pump, the platelet liquid enters the plasma bag 20 along the third channel opening 5.3 and the fourteenth channel 43 of the plasma pump, and the step can belong to step 1 or the step of blood returning, then, step 2, starting the PRP pump 4, so that the liquid preserved in advance in the platelet preserving bag 21, such as physiological saline or plasma of the patient, enters the PRP pump 4 along the twelfth channel 41 and the fourth channel port 4.4 of the PRP pump, and under the action of the PRP pump 4, the liquid in the platelet preserving bag 21 enters the collecting bag 23 along the second channel port 4.2 and the eleventh channel 40 of the PRP pump, preferably, a small part of the liquid flow in the collecting bag 23 enters the plasma bag 20, the liquid amount in the collecting bag 23 is reduced, the pressure is reduced, and the collecting bag 23 is convenient to detach; and 3, starting the plasma pump 5 and the PRP pump 4, enabling the liquid in the plasma bag 20 to enter the plasma pump 5 along the fourteenth pipeline 43 and the third pipeline 5.3 of the plasma pump, enabling the liquid in the collection bag 23 to enter the lower-layer channel opening of the collection bag 23 along the second channel opening 5.2 and the thirteenth pipeline 42 of the plasma pump under the action of the plasma pump 5, mixing the liquid in the collection bag 23, enabling the platelets to be uniform in the liquid in the collection bag 23, enabling the liquid in the collection bag 23 to enter the PRP pump 4 along the upper-layer channel opening of the collection bag 23, the eleventh pipeline 40 and the second channel opening 4.2 of the PRP pump, enabling the liquid to enter the fourth channel opening 4.4 of the PRP pump and enabling the liquid to enter the platelet storage bag 21 under the action of the PRP pump 4, and completing the transfusing process, wherein the very pure platelets can be obtained through the process.

Preferably, the present application further has a return function, that is, after the last blood collection and return process is completed, the consumable further contains a lot of red blood cells, whole blood, and the red blood cells, whole blood, etc. that need to be removed, and it is best to collect and collect the blood, after the last blood collection and return process is completed, the whole blood pump 1 rotates, so that the saline in the saline bag 18 enters the whole blood pump 1 along the second pipeline 31 and the second channel 1.2 of the whole blood pump, and under the action of the whole blood pump 1, part of the saline enters the third pipeline 32 from the third channel 1.3 of the whole blood pump and finally enters the red blood cell bag 16, and another part of the saline enters the centrifugal pump 2 from the fourth channel 1.4 of the whole blood pump along the fourth pipeline 33 and the first channel 2.1 of the centrifugal pump, and part of the blood in the whole blood pump 1 and part of the blood in the centrifugal pump 2 flows through the saline clamp 12 of the centrifugal pump 2 along the second channel 2.2 of the centrifugal pump, The fifth pipeline 34 enters the whole blood temporary storage bag 17, the whole blood pump 1 rotates reversely to drive the physiological saline and the blood in the whole blood temporary storage bag 17 to enter the centrifugal pump 2 along the fifth pipeline 34 and the centrifugal pump second passage port 2.2, and the physiological saline and the blood in the whole blood temporary storage bag 17 enter the blood bag along the fourth pipeline 33, the whole blood pump fourth passage port 1.4, the whole blood pump 1, the whole blood pump second passage port 1.2, the second pipeline 31 and the blood taking needle 25 from the centrifugal pump first passage port 2.1.

This application still has the function of red blood cell concentration fine setting, when the concentration of red blood cell in the whole blood is too high, or other reasons lead to the red blood cell concentration in the whole blood too high, the concentration of red blood cell needs to be diluted for plasma in the PRP pump 4 or plasma in the plasma bag 20 enter the circulating pump 3 along PRP pump first access 4.1, tenth pipeline 39, circulating pump second access 3.2 in, plasma enters centrifugal pump 2 along circulating pump first access 3.1, ninth pipeline 38, centrifugal pump fourth access 2.4 in, make plasma and whole blood mix, in order to reduce the concentration of red blood cell.

The switch can be added on each channel or pipeline, or the switch is used for replacing the saline clamp 12, the blood return clamp 13, the blood inlet clamp 14, the anticoagulant clamp 15 and the like, the switch can be a valve or a clamp, and the purpose of closing and opening the channel or pipeline can be achieved.

Example 3

A platelet collecting method for separating platelets from collected whole blood bag, using the platelet collecting device disclosed in embodiment 1 of the present application, the method uses fresh human blood for extracting platelets, inserts a blood collection needle 25 into a human blood vessel, then performs a first step, blood collection, during blood collection, starts a whole blood pump and an anticoagulant pump, opens a blood inlet clamp 14, mixes the blood and anticoagulant in the whole blood bag and enters the whole blood pump from a first passage port 1.1 of the whole blood pump along a first pipeline 30, closes a third valve 9, allows the blood and anticoagulant to reach a first passage port 2.1 of a centrifugal pump along a fourth pipeline 33 and enter the centrifugal pump, starts the centrifugal pump, divides the mixed flow of the blood and anticoagulant in two, half of the mixed flow enters a whole blood temporary storage bag 17 through a second passage port 2.2 and a fifth pipeline 34 of the centrifugal pump, and the other half of the mixed flow passes through a third passage port 2.3 of the centrifugal pump and along a sixth pipeline 35 and a separation bag 22 The layer channel port enters the separation bag 22, and under the centrifugal action of the centrifugal pump, the blood in the separation bag 22 is layered, so that the blood is separated into plasma at an upper layer and red cell fluid at a lower layer, the platelets are in the plasma, the red cell fluid at the lower layer enters the first pipeline 30 along the lower layer channel port of the separation bag 22 and finally enters the red cell bag 16 for preservation, the PRP pump is started and the PRP clamp 24 is opened, the fourth valve 10 is closed, the plasma in the separation bag 22 enters the eighth pipeline 37 along the upper layer channel port of the separation bag 22 and enters the third channel port 4.3 of the PRP pump along the eighth pipeline 37, the plasma in the PRP pump enters the PRP pump along the second channel port 4.2 of the PRP pump, the eleventh pipeline 40 and the upper layer channel port of the collection bag 23, and preferably, the collection bag 23 can be placed in a centrifugal barrel for separation, so that the plasma and the platelets are layered, the plasma pump is turned on so that plasma enters the thirteenth conduit 42 along the lower port of the collection bag 23, enters the plasma pump along the second port 5.2 of the plasma pump, and so that plasma in the plasma pump enters the fourteenth conduit 43 and ultimately the plasma bag 20 along the first port 5.1 of the plasma pump, the fifteenth conduit 44 of the plasma pump, the fourth port 5.4 of the plasma pump, the third port 5.3 of the plasma pump, while platelets in the plasma remain in the collection bag 23.

In the second step, blood returning is performed, the blood in the whole blood temporary storage bag 17 enters the centrifugal pump along the fifth pipeline 34 and the second passage port 2.2 of the centrifugal pump, and enters the separation bag 22 from the third passage port 2.3 of the centrifugal pump along the sixth pipeline 35 and the middle passage port of the separation bag 22, the blood is centrifugally separated into plasma at the upper layer and high-concentration blood cell liquid at the lower layer in the separation bag 22, the high-concentration blood cell liquid at the lower layer enters the first pipeline 30 along the lower passage port of the separation bag 22 and finally enters the red blood cell bag 16 for preservation, the plasma in the separation bag 22 enters the eighth pipeline 37 along the upper passage port of the separation bag 22 and enters the third passage port 4.3 of the PRP pump along the eighth pipeline 37 and enters the PRP pump, the plasma in the PRP pump enters the collection bag 23 along the second passage port 4.2 of the PRP pump, the eleventh pipeline 40 and the upper passage port of the collection bag 23, and the collection bag 23 can be placed in a centrifugal barrel for separation as a preference, the plasma and the platelets are layered, the plasma pump is started, the plasma enters the thirteenth pipeline 42 along the lower layer passage port of the collection bag 23, enters the plasma pump along the second passage port 5.2 of the plasma pump, the plasma in the plasma bag 20 enters the plasma pump along the fourteenth pipeline 43 and the third passage port 5.3 of the plasma pump, the plasma enters the whole blood pump from the first passage port 5.1 of the plasma pump along the fourth pipeline 33 and the fourth passage port 1.4 of the whole blood pump under the action of inversion of the plasma pump, the high-concentration red cell liquid in the red blood cell bag 16 also enters the whole blood pump along the third pipeline 32 and the third passage port 1.3 of the whole blood pump due to the inversion of the whole blood pump, the plasma and the high-concentration red cell liquid in the whole blood pump are mixed, the blood enters the human body along the second passage port 1.2 of the whole blood pump and the second pipeline 31 of the whole blood pump 25, the blood returns to the human body again, and the loss of the human body, blood return is completed and platelet fluid is stored in the collection bag 23.

Step 1, performing blood sampling and blood returning for multiple times to increase the volume of platelet liquid in the collection bag 23 continuously, storing a large amount of platelet liquid in the collection bag 23, wherein the platelet liquid is a combination of a large amount of platelets and a small amount or trace amount of plasma, placing the collection bag 23 serving as a part of the centrifugal bag into a centrifugal barrel, taking out the centrifugal bag from the centrifugal barrel after the centrifugal process is finished, starting a plasma pump, allowing the plasma in the collection bag 23 to enter a thirteenth pipeline 42 along a channel port on the lower layer of the collection bag 23 and enter a plasma pump along a second channel port 5.2 of the plasma pump, and allowing the platelet liquid to enter the plasma bag 20 along a third channel port 5.3 and a fourteenth channel 43 of the plasma pump; step 2, starting the PRP pump, so that the liquid preserved in advance in the platelet preserving bag 21, such as physiological saline or plasma of the patient, enters the PRP pump along the twelfth pipeline 41 and the fourth channel port 4.4 of the PRP pump, and under the action of the PRP pump, the liquid in the platelet preserving bag 21 enters the collecting bag 23 along the second channel port 4.2 and the eleventh pipeline 40 of the PRP pump, preferably, a small part of the liquid flow in the collecting bag 23 enters the plasma bag 20, the liquid amount in the collecting bag 23 is reduced, the pressure is reduced, and the collecting bag 23 is convenient to detach; and 3, starting a plasma pump and a PRP pump, enabling liquid in the plasma bag 20 to enter the plasma pump along the fourteenth pipeline 43 and the third port 5.3 of the plasma pump, enabling the liquid to enter the lower-layer channel port of the collection bag 23 along the second channel port 5.2 and the thirteenth pipeline 42 of the plasma pump under the action of the plasma pump, mixing the liquid in the collection bag 23, enabling platelets to be uniform in the liquid in the collection bag 23, enabling the liquid in the collection bag 23 to enter the PRP pump along the upper-layer channel port of the collection bag 23, the eleventh pipeline 40 and the second channel port 4.2 of the PRP pump, enabling the liquid to enter the fourth channel port 4.4 and the twelfth pipeline 41 of the PRP pump into the platelet storage bag 21 under the action of the PRP pump, and completing the transfusion process, so that very pure platelets can be obtained.

Preferably, the blood collection and return system further has a return function, that is, after the last blood collection and return process is completed, the consumable further contains a lot of red blood cells, whole blood, and the red blood cells, whole blood and the like which need to be removed, and it is best to collect and collect the blood, after the last blood collection and return process is completed, the whole blood pump rotates, so that the normal saline in the normal saline bag 18 enters the whole blood pump along the second pipeline 31 and the second channel 1.2 of the whole blood pump, and part of the normal saline enters the third pipeline 32 and finally enters the red blood cell bag 16 from the third channel 1.3 of the whole blood pump under the action of the whole blood pump, another part of the normal saline enters the centrifugal pump from the fourth channel 1.4 of the whole blood pump along the fourth pipeline 33 and the first channel 2.1 of the centrifugal pump, and the part of the blood in the whole blood pump and the part of the blood in the centrifugal pump along the second channel 2.2, 2, The fifth pipeline 34 enters the whole blood temporary storage bag 17, the whole blood pump reversely rotates to drive the physiological saline and the blood in the whole blood temporary storage bag 17 to enter the centrifugal pump along the fifth pipeline 34 and the second passage port 2.2 of the centrifugal pump, and the physiological saline and the blood enter the human body from the first passage port 2.1 of the centrifugal pump along the fourth pipeline 33, the fourth passage port 1.4 of the whole blood pump, the second passage port 1.2 of the whole blood pump, the second pipeline 31 and the blood taking needle 25.

This application still has the function of red blood cell concentration fine setting, when the concentration of red blood cell in the whole blood is too high, or other reasons lead to the red blood cell concentration in the whole blood too high, the concentration of red blood cell needs to be diluted for in the plasma in the PRP pump or the plasma in plasma bag 20 gets into the circulating pump along PRP pump first access 4.1, tenth pipeline 39, circulating pump second access 3.2, plasma gets into in the centrifugal pump along circulating pump first access 3.1, ninth pipeline 38, centrifugal pump fourth access 2.4, make plasma and whole blood mix, in order to reduce the concentration of red blood cell.

The above description is only a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Although the embodiments of the present application have been described with reference to the accompanying drawings, it is not intended to limit the scope of the present application, and it should be understood by those skilled in the art that various modifications and variations can be made without inventive effort by those skilled in the art.

Claims

1. A platelet collection device, characterized by: comprises a monitoring box (26), wherein a whole blood pump (1), a centrifugal pump (2), a circulating pump (3), a PRP pump (4), a plasma pump (5) and an anticoagulant pump (6) are arranged in the monitoring box (26), the whole blood pump (1), the centrifugal pump (2), the PRP pump (4) and the plasma pump (5) are respectively provided with at least four passage ports, the circulating pump (3) and the anticoagulant pump (6) are respectively provided with at least two passage ports, the four passage ports of the whole blood pump (1) are respectively connected with the centrifugal pump (2), the plasma pump (5) and a red blood cell bag (16), the passage ports of the centrifugal pump (2) are also connected with a separation bag (22), the circulating pump (3) and a temporary storage whole blood bag (17), the passage ports of the PRP pump (4) are also connected with the separation bag (22), the collection bag (23) and the plasma pump (20), the whole blood pump (1) is connected with a blood taking needle (25) and a physiological saline bag (18) through a shared pipeline, and two passage openings of the whole blood pump are connected with the blood taking needle (25);

in the monitoring box, switches are arranged between the pumps, between the pumps and the blood taking needles and between the pumps and the bags.

2. A platelet collection device according to claim 1 wherein a separation bag (22) is further connected to the red blood cell bag (16), and a switch is provided in the conduit between the red blood cell bag (16) and the separation bag (22).

3. A platelet collection device according to either one of claims 1 or 2 wherein the switch comprises a clamp, a valve.

4. A platelet collection device according to claim 1 wherein the anticoagulant pump (6) is connected to a whole blood pump (1) and an anticoagulant bag (19).

5. A platelet collection device according to claim 1 wherein a platelet storage bag (21) is also connected to the PRP pump (4).

6. The platelet collecting device according to claim 1, wherein the whole blood pump (1), the centrifugal pump (2), the circulating pump (3), the PRP pump (4), the plasma pump (5) and the anticoagulant pump (6) are distributed in the monitoring box (26) in a counterclockwise manner.

7. A platelet collection device according to claim 1 wherein the collection bag (23) and the separation bag (22) are integrally connected to form a centrifuge bag.

8. A platelet collection device according to either one of claims 1 or 7 further including a centrifuge bucket for centrifugation of the collection bag (23) or liquid in the centrifuge bag.

9. A platelet collection device according to claim 1, wherein the whole blood pump (1) is connected to the red blood cell bag (16) through a third conduit (32), the third conduit (32) is connected to a pressure monitoring device, and the third conduit (32) is provided with a first valve (7);

centrifugal pump (2) and blood pump (5) are connected respectively through forked fourth pipeline (33) in whole blood pump (1), the pressure monitoring devices is connected in fourth pipeline (33) that centrifugal pump (2) were connected in whole blood pump (1), be provided with second valve (8) on fourth pipeline (33) that centrifugal pump (2) were connected in whole blood pump (1), the pressure monitoring devices is connected in fourth pipeline (33) that blood pump (5) were connected in whole blood pump (1), be provided with third valve (9) on fourth pipeline (33) that blood pump (5) were connected in whole blood pump (1).

10. A platelet collection device according to claim 1, wherein the PRP pump (4) is connected to the plasma container via a twelfth tube (41), the twelfth tube (41) being connected to the pressure monitoring device, the twelfth tube (41) being provided with a fourth valve (10);

the full blood pump (1) is connected the end branch of fourth pipeline (33) of plasma pump (5), and plasma pump (5) is connected to the terminal one end of fourth pipeline (33), and the other end that the terminal other end of fourth pipeline (33) passes through fifteenth pipeline (44) and connects the other end of plasma pump (5), is provided with fifth valve (11) on fifteenth pipeline (44), and fifteenth pipeline (44) connection pressure monitoring devices.