CN213544172U - Sedimentation device - Google Patents

Abstract

The utility model provides a subside device relates to cell film-making technical field, include: the device comprises a glass slide, a base and a sedimentation piece with openings at two ends; a sedimentation cavity is formed between the two open ends of the sedimentation piece; the slide is positioned on the base; the base is provided with a first adsorption part, the sedimentation piece is provided with a second adsorption part, and the first adsorption part and the second adsorption part are matched for adsorption so that one opening end of the sedimentation piece is abutted against the glass slide on the base. Because subside and base are connected through absorbent mode, so, when actual installation, only need place the slide on the base in one step earlier, then, place subside on the slide, through the adsorption affinity that produces between first absorption portion and the second absorption portion, can press from both sides tight slide and make slide and subside form the groove-shaped structure that holds subside liquid to accomplish the installation fast, can effectually reduce the time that the installation consumes, raise the efficiency.

Description

Sedimentation device

Technical Field

The utility model relates to a cell film-making technical field particularly, relates to a subside device.

Background

With the intensive research of cell biology, the research and application of the cell biology are gradually popularized to the medical field, and a pelleter is also called a liquid-based cell pelleter, which utilizes the pneumatic and hydraulic principles according to the liquid-based cytology principle to disperse, filter, collect and transfer the collected cell samples. For example, a rotating mechanism in the pelleter drives a filtering membrane cylinder to gently mix the cell samples uniformly, the whole cell collection process is controlled by a computer, and meanwhile, the biochemical principle is adopted to naturally adsorb the cells collected on the filtering membrane to the slide, so that the purposes of perfect cell transfer and uniform single-layer tiling are achieved, and the subsequent dyeing and diagnosis are facilitated.

At present, when a slide is manufactured, a cell sedimentation slide loading device needs to be used, a sedimentation cylinder and a base in the cell sedimentation slide loading device adopt connection modes such as screws, when the cell sedimentation slide loading device is used, the sedimentation cylinder and the base need to be assembled by firstly carrying out operations such as knob screws, and then sedimentation is carried out.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a subside device to the not enough among the above-mentioned prior art to solve the current loaded down with trivial details problem that leads to the operating efficiency lower of subsiding slide loading attachment assembly step.

In order to achieve the above object, the embodiment of the present invention adopts the following technical solutions:

the utility model discloses an aspect provides a subside device, include: the device comprises a glass slide, a base and a sedimentation piece with openings at two ends; a sedimentation cavity is formed between the two open ends of the sedimentation piece; the slide is positioned on the base; the base is provided with a first adsorption part, the sedimentation piece is provided with a second adsorption part, and the first adsorption part and the second adsorption part are matched for adsorption so that one opening end of the sedimentation piece is abutted against the glass slide on the base.

Optionally, the first magnetic part is a first magnetic part, the second magnetic part is a second magnetic part, and the first magnetic part and the second magnetic part are matched for adsorption.

Optionally, the base includes a carrying station and an adsorption station, and the slide is located at the carrying station; the first adsorption part is positioned at the adsorption station; the orthographic projection of the second adsorption part on the base is at least partially positioned at the adsorption station.

Optionally, the second adsorption part is a sucker arranged on the sedimentation piece, and the sucker is matched with the first adsorption part for adsorption.

Optionally, the first adsorption part comprises an adsorption through hole arranged at the adsorption station and an air suction device; the air suction device is connected with the adsorption through hole pipeline and used for forming negative pressure through the air suction device so as to adsorb the second adsorption part.

Optionally, the second adsorption part is detachably connected with the sedimentation member.

Optionally, the sedimentation device further comprises a sealing ring, and the sealing ring is located at the opening where the sedimentation member abuts against the slide.

Optionally, a limiting part is further arranged on the base, and the limiting part is used for limiting the position of the slide on the base.

Optionally, the sedimentation member comprises a cylinder body with openings at two ends and a sedimentation part arranged on the cylinder body; the settling part is arranged at one opening end of the barrel in a surrounding mode, an annular cavity is formed by the settling part and the barrel in a surrounding mode, and the second adsorption part is located in the annular cavity.

Optionally, the sinking portion is made of an elastic material.

The beneficial effects of the utility model include:

the utility model provides a subside device, including slide, base and piece of subsiding, wherein, the both ends of subsiding the piece are provided with two openings. The sedimentation cavity is arranged in the sedimentation piece and is communicated with the two openings respectively, so that the sedimentation cavity is communicated with the outside, and the subsequent operation is facilitated. The base then holds carrier as the basis, can be used for placing the slide on its one side, and the piece that subsides then can correspond the setting on the slide to can be so that the piece that subsides is on the slide apart from the inner circle of the opening of the nearer one end of slide, make the slide can with the subside chamber cooperation in the piece that subsides or enclose and form a cell-shaped structure, should enclose the cell-shaped structure that forms promptly and communicate with the outside through another opening on the piece that subsides. Because subside and base are connected through absorbent mode, so, when actual installation, only need place the slide on the base in one step earlier, then, place subside on the slide, through the adsorption affinity that produces between first absorption portion and the second absorption portion, can press from both sides tight slide and make slide and subside form the groove-shaped structure that holds subside liquid to accomplish the installation fast, can effectually reduce the time that the installation consumes, raise the efficiency.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.

Fig. 1 is a schematic structural diagram of a settling device according to an embodiment of the present invention;

fig. 2 is a second schematic structural view of a settling device according to an embodiment of the present invention;

fig. 3 is a schematic structural diagram of a settling member of a settling device according to an embodiment of the present invention;

fig. 4 is a schematic structural diagram of a settling section of a settling device according to an embodiment of the present invention;

fig. 5 is a schematic structural view of a second adsorption part of a settling device according to an embodiment of the present invention;

fig. 6 is a third schematic structural view of a settling device according to an embodiment of the present invention;

fig. 7 is a fourth schematic structural view of a settling device according to an embodiment of the present invention.

Icon: 100-slide; 200-a base; 210-a limiting part; 300-a sedimentation member; 310-a settling chamber; 320-suction cup; 330-a sink portion; 340-a magnet; 350-cylinder.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention, as generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. It should be noted that, in the case of no conflict, various features in the embodiments of the present invention may be combined with each other, and the combined embodiments are still within the scope of the present invention.

It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate the position or positional relationship based on the position or positional relationship shown in the drawings, or the position or positional relationship which is usually placed when the product of the present invention is used, and are only for convenience of description and simplification of the description, but do not indicate or imply that the device or element referred to must have a specific position, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance.

Furthermore, the terms "horizontal", "vertical" and the like do not imply that the components are required to be absolutely horizontal or pendant, but rather may be slightly inclined. For example, "horizontal" merely means that the direction is more horizontal than "vertical" and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.

In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

The embodiment of the utility model provides an aspect, refer to fig. 1, provide a subside device, include: a slide 100, a base 200 and a sedimentation member 300 with both ends open; a settling chamber 310 is formed between both open ends of the settling member 300; slide 100 is positioned on base 200; the base 200 is provided with a first adsorption part, the sedimentation element 300 is provided with a second adsorption part, and the first adsorption part and the second adsorption part are matched for adsorption so that one opening end of the sedimentation element 300 is sealed and abutted with the slide 100 on the base 200.

Illustratively, the sedimentation device may comprise a slide 100, a base 200 and a sedimentation member 300, wherein two openings are provided at two ends of the sedimentation member 300, and the two ends may be opposite ends, or may be at the same side or at an included angle. A settling chamber 310 is arranged in the settling member 300, and the settling chamber 310 is respectively communicated with the two openings, so that the settling chamber 310 is communicated with the outside, and the subsequent operation is convenient. The base 200 serves as a basic carrier, one side of which can be used for placing the slide 100, the sedimentation member 300 can be correspondingly arranged on the slide 100, and the inner circle of the opening at the end of the sedimentation member 300 closer to the slide 100 can be positioned on the slide 100, so that the slide 100 can be matched with the sedimentation cavity 310 in the sedimentation member 300 or can form a groove-shaped structure in an enclosing way, namely, the groove-shaped structure formed in the enclosing way is communicated with the outside through another opening on the sedimentation member 300.

In order to make the sedimentation member 300 capable of meeting the sealing performance required during sedimentation, namely, the matching position of the slide 100 and the opening of the sedimentation member 300 covered by the slide 100 has better sealing performance, and leakage of sedimentation liquid in the sedimentation process is avoided, a first adsorption part can be arranged on the base 200, correspondingly, a second adsorption part is also arranged on the sedimentation member 300, so that the base 200 and the sedimentation member 300 can clamp the slide 100 positioned between the first adsorption part and the second adsorption part through the adsorption force generated between the first adsorption part and the second adsorption part, the sealing performance of the slide 100 and the opening covered by the slide 100 can be ensured, the possibility that the sedimentation member 300 is displaced relative to the base 200 in the sedimentation process can be effectively reduced, namely, in the normal sedimentation process, the sedimentation member 300 can keep higher stability relative to the base 200, and simultaneously, the slide 100 clamped between the sedimentation member 300 and the base 200 can keep higher stability relative to the base 200 and the sedimentation member 300 Stability, thereby ensuring that the settling step can be smoothly carried out. Because the sedimentation piece 300 and the base 200 are connected in an adsorption mode, in actual installation, the slide 100 is only required to be placed on the base 200 in one step, then the sedimentation piece 300 is placed on the slide 100, and the slide 100 and the sedimentation piece 300 can be clamped to form a groove-shaped structure for containing sedimentation liquid through the adsorption force generated between the first adsorption part and the second adsorption part, so that the installation is completed quickly, the time consumed by the installation can be effectively reduced, and the efficiency is improved.

In practical use, the settling device can be applied to a manual operation production line and can also be applied to an automatic production line, and the following description will be schematically given by taking a sheet making machine applied to the automatic production line as an example:

be provided with the transfer rail on the pelleter, set up base 200 on the track, the track transports base 200 in proper order through adding the piece station, adding storehouse station, annotating appearance station, rinsing station, dyeing station, getting storehouse station and getting piece station etc. to accomplish the process in each stage. After the base 200 is conveyed to the slide adding station, the slide adding mechanism takes the slide 100 out of the slide 100 bin and places the slide on the base 200, the rail continues to operate, the base 200 reaches the slide adding station, the slide adding mechanism takes the sedimentation member 300 out of the sedimentation bin and places the sedimentation member on the slide 100, at the moment, the slide 100 completely covers one opening of the sedimentation member 300, and the sedimentation member 300 and the base 200 clamp the slide 100 under the action of the second adsorption part and the first adsorption part, so that the purpose of sealing one opening of the sedimentation member 300 is achieved. The rail is continuously transported, the base 200 reaches a sample injection station, the sample injection mechanism injects a sample liquid into the sedimentation cavity 310 of the groove-shaped structure, cells in the sample liquid are settled under the action of gravity, after the sample liquid is settled in place, the base 200 comes to a rinsing station, the rinsing mechanism is used for cleaning, redundant liquid in the sedimentation cavity 310 is pumped out, then the rail is continuously transported, the base 200 comes to a dyeing station, after the dyeing mechanism dyes the slide 100, the base 200 moves to a bin taking station, the bin taking mechanism takes out the sedimentation piece 300 from the base 200 (the sedimentation piece can be transferred to other mechanisms or can be directly discarded, and no matter which way is adopted, the relevant medical regulations are met), the base 200 moves to a piece taking station, and the piece taking mechanism takes out the prepared slide 100 on the base 200 and transfers the prepared slide 100 to the next link procedure. Use and subside the device, in the integration automation line that can be quick, improve the efficiency of film-making, simultaneously, guaranteed the reliability and the stability of film-making.

Optionally, the first magnetic part is a first magnetic part, the second magnetic part is a second magnetic part, and the first magnetic part and the second magnetic part are matched for adsorption.

For example, as shown in fig. 2 and fig. 6, the fitting and suction between the base 200 and the sedimentation member 300 can be achieved by magnetic attraction, that is, a first magnetic attraction portion is disposed on the base 200, and a second magnetic attraction portion is disposed on the sedimentation member 300, so that when the sedimentation member 300 is placed on the slide 100, a good fitting and suction can be formed between the slide 100 and the base 200. The mode of magnetism is inhaled can further simplification structure and assembly step for when the installation of piece 300, only through placing the back in place, the piece 300 that subsides adsorbs through magnetic attraction with base 200 nature, and need not to carry on loaded down with trivial details installation again. When the magnetic attraction is selected, the following methods can be included but not limited to:

one of the setting modes is as follows: the first magnetic part can be a permanent magnet 340, correspondingly, the second magnetic part can also be a permanent magnet 340, but when the first magnetic part and the second magnetic part are arranged, two opposite ends are two ends with different polarities, so that the adsorption force can be generated in a certain distance.

The other setting mode is as follows: the first magnetic part can be a permanent magnet 340, correspondingly, the second magnetic part can be metal, and the metal is acted by magnetic force, so that stable adsorption is formed between the first magnetic part and the second magnetic part.

The other setting mode is as follows: the first magnetic part can be an electromagnet 340, correspondingly, the second magnetic part can be metal, when needed, the electromagnet 340 can be matched with the iron core to generate a magnetic field when being electrified, and the metal is acted by the magnetic field force to form stable adsorption between the first magnetic part and the second magnetic part.

The other setting mode is as follows: the first magnetic attraction portion may be an electromagnet 340, and correspondingly, the second magnetic attraction portion may be a permanent magnet 340.

In addition, when the magnetic pole is installed, the first magnetic attraction part and the second magnetic attraction part in the above embodiments may be exchanged, for example, in an embodiment where "the first magnetic attraction part may be the permanent magnet 340, and correspondingly, the second magnetic attraction part may be metal", the first magnetic attraction part may also be metal, and the second magnetic attraction part may be the permanent magnet 340. The arrangement between the various embodiments may also be combined.

Optionally, the base 200 includes a carrying station and an adsorption station, the slide 100 being located at the carrying station; the first adsorption part is positioned at the adsorption station; the orthographic projection of the second adsorption part on the base 200 is at least partially positioned at the adsorption station.

For example, as shown in fig. 2 and fig. 7, in order to form a more stable adsorption, the base 200 may further include a carrying station and an adsorption station, that is, the base 200 is divided into regions, the carrying station is adapted to (may be larger or smaller than) the size of the slide 100 and is used for placing the slide 100, an adsorption station may be further provided outside the carrying station, and the first adsorption part is provided at the adsorption station, at this time, in order to further improve the stability between the first adsorption part and the second adsorption part, at least a part (including all) of an orthographic projection of the second adsorption part on the base 200 on the sedimentation member 300 may be located in the adsorption station where the first adsorption part is located, that is, at least a part of the second adsorption part corresponds to the first adsorption part up and down, so that the two adsorption parts can perform adsorption more directly.

Optionally, the second adsorption part is a suction cup 320 disposed on the sedimentation member 300, and the suction cup 320 is adsorbed by matching with the first adsorption part.

For example, the second suction part may be a suction cup 320, and in order to facilitate the suction cup 320 to correspond to the first suction part of the suction station of the base 200, illustratively, a side lug may be further disposed on the outer side of the sedimentation member 300, and the extending direction of the side lug may be parallel to the base 200. In order to improve the suction capability of the suction cup 320, the surface of the first suction portion may be a flat surface which is flat and easy to suck. As shown in fig. 7, when the suction cup 320 is a cone-shaped structure, when the sedimentation member 300 is placed on the slide 100, the suction cup 320 on the side ear of the sedimentation member 300 can directly contact with the base 200, and when the suction cup 320 contacts with the surface of the first adsorption part by pressing during placement, air in the suction cup 320 can be discharged by gradual deformation, and when the suction cup is in place (the slide 100 and the sedimentation member 300 form a good seal), the suction cup 320 can be stably adsorbed on the surface of the first adsorption part by atmospheric pressure, and adsorption is completed. In addition, the suction cup 320 may be other adhesive substances, which can be adhered to the surface of the first suction portion, and the embodiment is not limited thereto. In addition, in order to further improve the stability of the suction, as shown in fig. 4, two side ears and two suction cups 320 may be symmetrically disposed, and of course, three, four, five, etc. may be disposed.

In another embodiment, the first suction part may be configured as a suction cup, and two suction cups are used for sucking each other, so as to realize stable suction.

In another embodiment, the suction cup may be provided in combination with a magnetic attraction manner, such as a metal, a permanent magnet 340, an electromagnet 340, etc., provided on the suction cup, so as to form a more stable installation relationship.

Optionally, the first adsorption part comprises an adsorption through hole arranged at the adsorption station and an air suction device; the air suction device is connected with the adsorption through hole pipeline and used for forming negative pressure through the air suction device so as to adsorb the second adsorption part.

For example, the first adsorption part may be an adsorption through hole located at the adsorption station and an air suction device connected to the adsorption through hole through a pipeline, and correspondingly, the second adsorption part may be a side lug disposed outside the sedimentation member 300, at this time, after the sedimentation member 300 is placed in place, since the second adsorption part corresponds to the adsorption through hole located at the adsorption station, the air suction device starts to operate, and negative pressure may be generated through the adsorption through hole, so as to adsorb the second adsorption part, thereby enabling the sedimentation member 300 and the base 200 to tighten the slide 100.

Alternatively, the second adsorption part is detachably connected to the settling member 300.

Illustratively, as shown in fig. 3 to 6, in order to further reduce the cost of tableting, the adsorption part and the settling member 300 may be detachably connected, meanwhile, the second adsorption part may be disposed outside the settling member 300, so that the second adsorption part is isolated from the settling chamber 310 of the settling member 300, that is, in the slide preparation, the contamination of the second adsorption part outside by the sample liquid in the sedimentation chamber 310 can be avoided, and at the same time, after the preparation, because the sedimentation member 300 is polluted by the specimen liquid, in order to meet the relevant regulations, the sedimentation member 300 needs to be discarded to avoid cross infection caused by secondary use, the second adsorption part can be disassembled before the discarding, and then the specimen liquid can be used as required, and the second adsorption part is correspondingly cleaned and disinfected, so that the second adsorption part can be repeatedly utilized, and the tabletting cost can be reduced. The detachable connection mode can be various modes such as a buckle, adsorption, a threaded connection and the like.

Optionally, the sedimentation device further comprises a sealing ring located at the opening where the sedimentation member 300 abuts the slide 100.

In an example, a sealing ring can be arranged at the opening, so that not only can damage caused by hard connection of the sedimentation member 300 and the slide 100 be effectively avoided, but also the sealing performance of the slide 100 for sealing the opening on the sedimentation member 300 can be further improved under the action of adsorption force. The sealing ring may be a rubber ring, such as a Thermoplastic Elastomer (TPE), a resin ring, or the like.

Optionally, a position-limiting part 210 is further disposed on the base 200, and the position-limiting part 210 is used for limiting the position of the slide 100 on the base 200. For example, as shown in fig. 2, a rib is provided on the base 200, when the slide 100 is placed on the base 200 by the slide adding mechanism, the rib can limit the slide 100, so as to form an obvious in-place limit for the slide 100, and at the same time, can limit the displacement of the slide 100, and prevent the slide 100 from being displaced after being placed. In addition, two opposite flanges can be arranged to limit the left and right sides of the slide 100.

Alternatively, as shown in fig. 3 to 6, the settling member 300 includes a cylinder 350 having openings at both ends thereof and a settling part 330 disposed on the cylinder 350; the settling part 330 is annularly arranged at an opening end of the cylinder 350, the settling part 330 and the cylinder 350 are enclosed to form an annular cavity, and the second adsorption part is located in the annular cavity.

Alternatively, as shown in fig. 4, the settling part 330 is made of rubber.

For example, the settling member 300 may include a cylinder 350 and a settling part 330 having openings at both ends, and the settling part 330 may be provided at one opening. To facilitate the arrangement of the second adsorption part, the settling part 330 and the cylinder 350 may be enclosed to form an annular cavity, and the second adsorption part is arranged in the annular cavity. The subsidence part 330 can be made of an elastic material, such as silicone, rubber, such as Thermoplastic Elastomer (TPE), etc., which can deform under the suction force of the first and second suction parts to better seal the opening of the slide 100. Meanwhile, the damage to the slide caused by the sedimentation member 300 can be further improved. The second absorption part may be metal, magnet 340, etc., and in cooperation, the first absorption part may be magnet 340, metal, etc. To reduce manufacturing costs, barrel 350 may also be provided as a lower cost plastic, such as polypropylene, polycarbonate, and the like. When provided, the sinkers 300 may be hollow cylindrical cartridges, prismatic cartridges, or the like, as shown in fig. 1. In the above embodiment, as shown in fig. 5, the second adsorption part may be annularly disposed so as to improve the stability of adsorption.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. A sedimentation device, comprising: the device comprises a glass slide, a base and a sedimentation piece with openings at two ends; a sedimentation cavity is formed between the two open ends of the sedimentation piece; the slide is positioned on the base; the base is provided with a first adsorption part, the sedimentation piece is provided with a second adsorption part, and the first adsorption part and the second adsorption part are matched for adsorption so that one opening end of the sedimentation piece is sealed and abutted against the glass slide on the base.

2. The settling device as claimed in claim 1, wherein the first absorption part is a first magnetic absorption part, the second absorption part is a second magnetic absorption part, and the first magnetic absorption part and the second magnetic absorption part are matched for absorption.

3. The sedimentation device according to claim 1, wherein the base comprises a carrier station and an adsorption station, the slide being located at the carrier station; the first adsorption part is positioned at the adsorption station; the orthographic projection of the second adsorption part on the base is at least partially positioned at the adsorption station.

4. The settling device as claimed in claim 3, wherein the second suction part is a suction cup provided on the settling member, the suction cup sucking with the first suction part.

5. The settling device as claimed in claim 3, wherein the first adsorption part comprises an adsorption through hole arranged at the adsorption station and an air suction device; the air suction device is connected with the adsorption through hole through a pipeline and used for forming negative pressure through the air suction device so as to adsorb the second adsorption part.

6. The settling device as claimed in any one of claims 1 to 5, wherein the second adsorption part is detachably connected to the settling member.

7. The sedimentation device according to any one of claims 1 to 5, further comprising a sealing ring at the opening where the sedimentation member abuts the slide.

8. The sedimentation device according to any one of claims 1 to 5, wherein a stopper portion for restricting the position of the slide on the base is further provided on the base.

9. The settling device as claimed in any one of claims 1 to 5, wherein the settling member comprises a cylindrical body having openings at both ends thereof and a settling part provided on the cylindrical body; the settling part is annularly arranged at one opening end of the barrel body, an annular cavity is formed by the settling part and the barrel body in an enclosing mode, and the second adsorption part is located in the annular cavity.

10. A settler according to claim 9, wherein said settler is made of an elastomeric material.

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