CN213537877U - Nucleic acid extractor capable of quantitatively adding magnetic beads - Google Patents

Nucleic acid extractor capable of quantitatively adding magnetic beads Download PDF

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Publication number
CN213537877U
CN213537877U CN202021953621.9U CN202021953621U CN213537877U CN 213537877 U CN213537877 U CN 213537877U CN 202021953621 U CN202021953621 U CN 202021953621U CN 213537877 U CN213537877 U CN 213537877U
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nucleic acid
magnetic bead
groove
acid extractor
kit
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CN202021953621.9U
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Chinese (zh)
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张健
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Tianjin Zhongyi Heyuan Medical Technology Co ltd
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Tianjin Zhongyi Heyuan Medical Technology Co ltd
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Abstract

The utility model provides a nucleic acid extractor for quantitatively adding magnetic beads, which is characterized by comprising a nucleic acid extractor body and a magnetic bead adding mechanism; the utility model discloses increased the magnetic bead on nucleic acid extraction appearance and added the mechanism, can carry out the magnetic bead to the kit and add, realized the magnetic bead of nucleic acid extraction appearance and added the function, reduced the purchase of nucleic acid magnetic bead extraction kit, reduced the experiment cost, can obtain nucleic acid magnetic bead extraction kit at any time, make the experiment progress avoid laboratory current resource restriction; the utility model discloses increased the magnetic bead and added the mechanism, this magnetic bead adds the simple operation of mechanism through promoting the kit, makes every test tube of kit obtain a magnetic bead, and multiple repetition operation has realized the process according to actual conditions control magnetic bead quantity, has reached the purpose of simplifying the operating procedure, has improved the work efficiency of nucleic acid extraction appearance.

Description

Nucleic acid extractor capable of quantitatively adding magnetic beads
Technical Field
The utility model relates to a nucleic acid extraction appearance technical field, concretely relates to nucleic acid extraction appearance of magnetic bead is added to ration.
Background
As is well known, a nucleic acid extraction instrument is an instrument for automatically completing the work of extracting nucleic acid from a sample by using a matched nucleic acid extraction reagent, and is widely applied to the fields of conventional scientific research, genomics, disease control systems, food safety, forensic science and the like; at present, nucleic acid magnetic bead extraction kits for extracting nucleic acid in laboratories are purchased, and the number of magnetic beads in each test tube is equal according to different specifications of the nucleic acid magnetic bead extraction kits; from the prior art: 1. the nucleic acid extractor needs to be provided with a plurality of nucleic acid magnetic bead extraction kits, so that the experiment cost is increased; 2. the concentration of the existing reagent in a laboratory needs to be adjusted according to the specification of the nucleic acid magnetic bead extraction kit, which wastes time and labor and causes low efficiency of nucleic acid extraction.
Disclosure of Invention
According to the technical problem, the utility model provides a nucleic acid extractor for quantitatively adding magnetic beads, which is characterized in that the nucleic acid extractor comprises a nucleic acid extractor body and a magnetic bead adding mechanism; a magnetic bead adding mechanism is arranged on the left side wall inside the nucleic acid extractor body;
a reagent box groove is formed in the left side wall of the nucleic acid extraction instrument body, a limiting block is mounted at the bottom of the right side wall of the reagent box groove, and a magnetic bead adding hole is formed in the upper end face of the nucleic acid extraction instrument body;
the magnetic bead adding mechanism consists of a movable plate, a top block and a spring, a fixed block is arranged on the left side wall in the nucleic acid extractor body, a magnetic bead groove is formed in the upper end face of the fixed block, the magnetic bead groove is formed in the lower side of a magnetic bead adding hole, fixed holes are formed in the bottom face of the magnetic bead groove, the number of the fixed holes is N, N is more than or equal to 2, a rectangular through groove is formed in the left side wall of the fixed block, dropping holes are formed in the lower end face of the fixed block, the number of the dropping holes is N, N is more than or equal to 2, and bead dropping pipes are arranged at the bottom of the dropping holes;
the movable plate is arranged in the rectangular through groove and consists of a vertical plate and a transverse plate, the transverse plate is arranged in the rectangular through groove, movable holes are formed in the transverse plate, the number of the movable holes is N, N is more than or equal to 2, the vertical plate is arranged at the right end of the transverse plate, and the vertical plate and the transverse plate are of an integrated structure;
the riser is connected with the one end of spring, the other end of spring is connected with the lateral wall in reagent box groove.
The utility model has the advantages that: the utility model discloses increased the magnetic bead on nucleic acid extraction appearance and added the mechanism, can carry out the magnetic bead to the kit and add, realized the magnetic bead of nucleic acid extraction appearance and added the function, reduced the purchase of nucleic acid magnetic bead extraction kit, reduced the experiment cost, can obtain nucleic acid magnetic bead extraction kit at any time, make the experiment progress avoid laboratory current resource restriction;
the utility model discloses increased the magnetic bead and added the mechanism, this magnetic bead adds the simple operation of mechanism through promoting the kit, makes every test tube of kit obtain a magnetic bead, and multiple repetition operation has realized the process according to actual conditions control magnetic bead quantity, has reached the purpose of simplifying the operating procedure, has improved the work efficiency of nucleic acid extraction appearance.
Drawings
FIG. 1 is a schematic view of the overall appearance of the present invention;
FIG. 2 is a cross-sectional view of the present invention without magnetic beads added;
FIG. 3 is a cross-sectional view of the present invention with magnetic beads added;
FIG. 4 is a schematic view of the movable plate of the present invention;
fig. 5 is a structural schematic of the fixing block of the present invention.
As shown in the figure: the method comprises the following steps of 1-moving plate, 11-vertical plate, 12-horizontal plate, 13-moving hole, 2-fixed block, 21-magnetic bead groove, 22-fixed hole, 23-rectangular through groove, 24-dropping hole, 25-dropping tube, 3-magnetic bead kit, 4-spring, 5-nucleic acid extractor body, 51-reagent kit groove, 52-magnetic bead adding hole, 53-limiting block and 6-magnetic bead adding mechanism.
Detailed Description
Example 1
The utility model provides a nucleic acid extractor for quantitatively adding magnetic beads, which is characterized by comprising a nucleic acid extractor body 5 and a magnetic bead adding mechanism 6; a magnetic bead adding mechanism 6 is arranged on the left side wall inside the nucleic acid extractor body 5;
a reagent box groove 51 is formed in the left side wall of the nucleic acid extraction instrument body 5, a limiting block 53 is arranged at the bottom of the right side wall of the reagent box groove 51, and a magnetic bead adding hole 52 is formed in the upper end face of the nucleic acid extraction instrument body 5;
the magnetic bead adding mechanism 6 consists of a movable plate 1, a top block 2 and a spring 4, a fixed block 2 is arranged on the left side wall in the nucleic acid extractor body 5, a magnetic bead groove 21 is formed in the upper end face of the fixed block 2, the magnetic bead groove 21 is formed in the lower side of a magnetic bead adding hole 52, fixed holes 22 are formed in the bottom face of the magnetic bead groove 21, the number of the fixed holes 22 is N, N is larger than or equal to 2, a rectangular through groove 23 is formed in the left side wall of the fixed block 2, dropping holes 24 are formed in the lower end face of the fixed block 2, the number of the dropping holes 24 is N, N is larger than or equal to 2, and a bead dropping pipe 25 is arranged at;
a movable plate 1 is arranged in the rectangular through groove 23, the movable plate 1 is composed of a vertical plate 11 and a transverse plate 12, the transverse plate 12 is arranged in the rectangular through groove 23, movable holes 13 are formed in the transverse plate 12, the number of the movable holes 13 is N, N is more than or equal to 2, the vertical plate 11 is arranged at the right end of the transverse plate 12, and the vertical plate 11 and the transverse plate 12 are of an integrated structure;
the vertical plate 11 is connected to one end of the spring 4, and the other end of the spring 4 is connected to a side wall of the reagent cassette well 51.
Example 2
When the utility model is used, firstly, magnetic beads are stocked in the magnetic bead groove 21 through the magnetic bead adding hole 52; then, the magnetic bead kit 3 is placed in the reagent kit groove 51, when the magnetic bead kit 3 touches the vertical plate 11, the magnetic bead kit 3 is pushed into the reagent kit groove 51 with force, in the process, the movable plate 11 moves rightwards in the rectangular through groove 23, the spring 4 contracts, magnetic beads pass through the fixed hole 22 from the magnetic bead groove 21 and enter the movable hole 13, and are driven by the movable plate 11 to move rightwards until the vertical plate 11 touches the limit block 53, the movable hole 13 is overlapped with the falling hole 24, and the magnetic beads fall from the falling hole 24, pass through the bead falling pipe 25 and fall into the magnetic bead kit 3; then the force is uniformly applied, the spring recovers deformation, the magnetic bead kit 3 is pushed leftwards until the movable hole 13 is superposed with the fixed hole 22, and the next magnetic bead enters the movable hole; then, the magnetic beads can be quantitatively put in by repeating the operation according to the preset addition amount of the magnetic beads.
The basic principles and the main features of the invention and the advantages of the invention have been shown and described above. The utility model discloses each part that mentions is the common technique in prior art, and the technical personnel of this trade should understand, the utility model discloses do not receive the restriction of above-mentioned embodiment, the description only is the explanation in above-mentioned embodiment and the description the principle of the utility model, under the prerequisite that does not deviate from the spirit and the scope of the utility model, the utility model discloses still can have various changes and improvement, these changes and improvement all fall into the protection of claim the utility model is within the scope. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (6)

1. A nucleic acid extractor for quantitatively adding magnetic beads is characterized by comprising a nucleic acid extractor body and a magnetic bead adding mechanism; a magnetic bead adding mechanism is arranged on the left side wall inside the nucleic acid extractor body;
a reagent box groove is formed in the left side wall of the nucleic acid extraction instrument body, a limiting block is mounted at the bottom of the right side wall of the reagent box groove, and a magnetic bead adding hole is formed in the upper end face of the nucleic acid extraction instrument body;
the magnetic bead adding mechanism consists of a movable plate, a top block and a spring, a fixed block is arranged on the left side wall in the nucleic acid extractor body, a magnetic bead groove is formed in the upper end face of the fixed block, the magnetic bead groove is formed in the lower side of a magnetic bead adding hole, a fixed hole is formed in the bottom face of the magnetic bead groove, a rectangular through groove is formed in the left side wall of the fixed block, a dropping hole is formed in the lower end face of the fixed block, and a bead dropping pipe is arranged at the bottom of the dropping hole;
a movable plate is arranged in the rectangular through groove and consists of a vertical plate and a transverse plate, the transverse plate is arranged in the rectangular through groove, a movable hole is formed in the transverse plate, and the vertical plate is arranged at the right end of the transverse plate;
the riser is connected with the one end of spring, the other end of spring is connected with the lateral wall in reagent box groove.
2. The nucleic acid extractor of claim 1, wherein the number of the fixed wells is N, N is 2 or more.
3. The nucleic acid extractor of claim 1, wherein the number of the dropping holes is N, N is 2 or more.
4. The nucleic acid extractor of claim 1, wherein the number of the kinetic wells is N, N is 2 or more.
5. The nucleic acid extractor of claim 1, wherein the vertical plate and the horizontal plate are integrally formed.
6. The nucleic acid extractor as claimed in claim 1, wherein the diameter of the moving well, the fixed well, and the falling well is larger than the diameter of the magnetic beads.
CN202021953621.9U 2020-09-09 2020-09-09 Nucleic acid extractor capable of quantitatively adding magnetic beads Active CN213537877U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202021953621.9U CN213537877U (en) 2020-09-09 2020-09-09 Nucleic acid extractor capable of quantitatively adding magnetic beads

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202021953621.9U CN213537877U (en) 2020-09-09 2020-09-09 Nucleic acid extractor capable of quantitatively adding magnetic beads

Publications (1)

Publication Number Publication Date
CN213537877U true CN213537877U (en) 2021-06-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202021953621.9U Active CN213537877U (en) 2020-09-09 2020-09-09 Nucleic acid extractor capable of quantitatively adding magnetic beads

Country Status (1)

Country Link
CN (1) CN213537877U (en)

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