CN213465450U - Waking activity device for rodent intracerebral microdialysis recording - Google Patents
Waking activity device for rodent intracerebral microdialysis recording Download PDFInfo
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- CN213465450U CN213465450U CN202121027247.4U CN202121027247U CN213465450U CN 213465450 U CN213465450 U CN 213465450U CN 202121027247 U CN202121027247 U CN 202121027247U CN 213465450 U CN213465450 U CN 213465450U
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Abstract
A waking activity device for rodent intracerebral microdialysis recording comprises an animal activity structure and a placement structure for placing the animal activity structure; a track control structure for accommodating a fixed pipeline on the body of the animal is arranged above the animal moving structure, and the track control structure is movably connected with the placing structure through a connecting structure; when the animal moves in the animal moving structure in the mode, the pipelines which are fixed in the track control structure and are positioned on the animal body can rotate along with the movement of the animal, and the pipelines cannot be wound or knotted. The utility model discloses can effectively practice thrift the cost of manufacture, and convenient operation, the practicality is strong.
Description
Technical Field
The utility model belongs to the field of experimental apparatus, concretely relates to is a clear-headed telecontrol equipment of rodent intracerebral microdialysis record.
Background
Rodent intracerebral microdialysis assays are assays for determining the secretion of chemical substances at specific locations of the brain of the central nervous system. Firstly, embedding a microdialysis probe at a specific position in the brain of an animal through an operation: the probe comprises a semipermeable membrane, is divided into a pipeline with inflow and outflow directions, can pump liquid at an inflow end, and collects chemical substances (such as neurotransmitter and other components) secreted at a recording position in the brain at an outflow end. In the experimental record, liquid (artificial cerebrospinal fluid) is slowly pumped into the probe inflow pipeline, and meanwhile, effluent liquid in the probe outflow pipeline is collected, so that sample acquisition of micro-dialysis in rodent brain is realized. In the whole recording process, rodents (rats and mice) do not need to be anesthetized, are conscious and freely move in a certain space range, can well reflect the secretion condition of chemical substances (such as components such as neurotransmitter) in a target brain area under the condition that the rodents are conscious and freely move, and then measure and analyze the chemical components of the liquid after the recording is finished.
At present, the animal intracerebral microdialysis product for waking, freely moving and exercising is a foreign product, and has the following defects: 1. the existing commercial animal moving structure is square, so that the free movement of animals is limited; 2. the gravity center of the existing device is on one side, so that the device is unstable in placement and the structure is easy to damage; 3. the whole set of equipment in specific use is foreign products, the price is high, and a plurality of inconveniences exist in the purchasing and using processes, such as slow progress of import approaches, high price of imported commodities, difficulty in accessory and maintenance, difficulty in technical support and the like.
The utility model provides a waking activity device for rodent brain microdialysis record aiming at the defects.
Disclosure of Invention
In order to overcome the problems in the background art, the utility model provides a sober activity device for rodent brain microdialysis recording.
A waking activity device for rodent intracerebral microdialysis recording comprises an animal activity structure and a placement structure for placing the animal activity structure; a track control structure for accommodating a fixed pipeline on the body of the animal is arranged above the animal moving structure, and the track control structure is movably connected with the placing structure through a connecting structure; when the animal moves in the animal moving structure in the mode, the pipelines which are fixed in the track control structure and are positioned on the animal body can rotate along with the movement of the animal, and the pipelines cannot be wound or knotted. The utility model discloses can effectively practice thrift the cost of manufacture, and convenient operation, the practicality is strong.
Further, the placing structure is an iron stand platform, and the iron stand platform comprises a placing platform, a vertical rod arranged at the first end of the placing platform, and a horizontal rod perpendicular to the vertical rod; the horizontal rod and the vertical rod are movably connected through a connecting assembly; put animal activity structure in placing the platform upper end through this kind of mode, adjust the relative distance of placing the platform of horizontal pole and the relative perpendicular pole's of horizontal pole angle, the effective connection orbit control structure of rethread connection structure to guarantee the suitable distance between animal activity structure and the horizontal pole. The height and the angle of the position of the horizontal rod can be conveniently adjusted through the arrangement.
Further, the connecting assembly comprises a connecting ring arranged at the first end of the horizontal rod, and a threaded cap arranged on one side of the connecting ring; one side of the connecting ring is provided with a threaded hole for the threaded cap to extend into; the effect of connecting the horizontal rod and the vertical rod is achieved by extending the threaded cap into the threaded hole. The connection mode is convenient to operate, and the angle between the horizontal rod and the vertical rod is effectively guaranteed to be adjusted.
Further, the track control structure comprises a rotating ring for fixing the probe plastic tube and a fixing structure arranged at the lower end of the rotating ring and used for connecting an animal; the fixing structure comprises a connecting wire connected with the swivel, a connecting hook arranged at the lower end of the connecting wire and a fixing ring fixed on the animal body; the fixing ring is hung on the connecting hook; the fixing ring is fixed on the animal body in such a way, the probe plastic pipe is fixed on the rotating ring, and the probe plastic pipe is fixed at the lower end of the horizontal rod through the connecting structure. The device effectively meets the function of recording the brain microdialysis of the conscious and freely moving animals.
Furthermore, the swivel comprises a first connecting column and a second connecting column positioned at the outer side of the first connecting column, the second connecting column can relatively rotate relative to the first connecting column, and the second connecting column cannot be separated from the first connecting column in the relative rotation process; the lower end of the second connecting column is fixedly connected with a connecting wire; when this kind of setting guaranteed that the animal position takes place to remove, second spliced pole and connecting wire can follow the removal of animal and take place to remove.
Further, a circular fixing plate is fixedly arranged on the outer side wall of the first connecting column, and a circular groove for the fixing plate to extend into and effectively rotate is formed in the inner side wall of the second connecting column; this kind of setting effectively guarantees that the second spliced pole can take place relative rotation relatively first spliced pole, and the second spliced pole can not take place to separate with first spliced pole at rotatory in-process.
Furthermore, a circular plate for fixing the probe plastic tube is arranged on the outer side wall of the second connecting column, and an independent through hole is formed in the upper end and the lower end of the circular plate; during the use, inflow and outflow pipeline are from animal end difference fixed connection in independent through hole, and when the animal position changed, it took place the rotation and made the relative first spliced pole of second spliced pole rotate to drive inflow and outflow pipeline, effectively avoided the phenomenon that the winding and knoing took place for the different pipelines in independent through hole.
Furthermore, 2 circular ring-shaped plates are arranged and are respectively positioned at the upper end and the lower end of the outer side of the second connecting column; at least 2 independent through holes of a single circular ring-shaped plate are arranged; this arrangement meets the need for effective separation of the pipelines in this experiment.
Or, the metal swivel ring of Harvard/Instech Stainless Steel rotors currently used is directly adopted to meet the use habit of experimenters, and the cost can be greatly reduced by only using the metal swivel ring.
Further, the connecting wires comprise first connecting wires arranged at the lower end of the second connecting column, and second connecting wires and third connecting wires symmetrically arranged at the lower end of the first connecting wires; the upper ends of the second connecting wire and the third connecting wire are intersected at one point and are connected with the first connecting wire, and the lower ends of the second connecting wire and the third connecting wire are intersected at one point and are connected with the connecting hook; the total branch is total, and the stability of the connecting wire in the free movement process of the animal is effectively ensured by arranging the second connecting wire and the third connecting wire in a parallel mode.
Further, a fixing piece is arranged at the junction point of the second connecting wire and the third connecting wire close to the upper end, and a sample collecting pipe for collecting liquid exuded from the animal body is movably arranged at the fixing piece; when the device is used, a sample is collected every 20 minutes, and the position of the sample collection pipe is fixed, so that the sample collection pipe is easy to collect, take and replace.
Further, the fixing plate is an inverted U-shaped fixing plate or a plane fixing plate.
Furthermore, the second connecting wire and the third connecting wire are provided with inverted U-shaped fixing pieces, the positions of the inverted U-shaped fixing pieces are arched, the first connecting wire is fixed at the combination ends of the inverted U-shaped fixing pieces, and the second connecting wire and the third connecting wire respectively penetrate out of and penetrate into the first surface and/or the second surface of the inverted U-shaped fixing pieces; this kind of setting can guarantee well that the stability on the connecting wire is fixed to the shape of falling U stationary blade.
Furthermore, the lower ends of the inverted U-shaped fixing pieces on the second connecting wires and the third connecting wires are provided with adhesive tapes for fixing the second connecting wires and the third connecting wires, so that stable pumping in and pumping out of liquid can be realized.
Furthermore, the second connecting wire and the third connecting wire penetrate through the upper end of the plane fixing piece and penetrate out of the lower end of the plane fixing piece; the provision of a planar stator simplifies the steps of making the device, since the total amount of sample collected is low.
Further, the animal movable structure is arranged into an animal movable barrel with a round bottom end, the animal movable barrel is placed on the placing table, and a water feeding structure is further arranged on one side of the animal movable barrel, which is far away from the vertical rod; the arrangement effectively ensures the free movement and survival requirements of the animals in the animal activity barrel.
The utility model has the advantages that: 1. by arranging the swivel with a simple structure or only using import metal conversion in equipment, the problem that the cost is high because an imported whole set of equipment is required when the experiment is carried out at present is effectively solved; 2. the stability of the device in the experiment is effectively ensured by arranging the first connecting wire, the second connecting wire and the third connecting wire with good stability; 3. the stability and the simplicity of collecting the animal liquid sample under the waking and free movement are effectively ensured by arranging the fixing plate and the sample collecting pipe and arranging the first connecting wire, the second connecting wire, the third connecting wire and the fixing plate; 4. the animal moving barrel with the round bottom end is arranged, so that the animal can freely move; 5. make the utility model discloses a cost is lower, and the sample of collecting is good through chemical composition detection and analysis back result, has fine practice effect, and whole collection sampling process is stable, simple and convenient, easy to operate.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a perspective view of the front view of the present invention;
FIG. 3 is a schematic view of the overall structure of the middle track control structure (the second connecting wire and the third connecting wire penetrate through and penetrate into the first surface of the inverted U-shaped fixing piece) according to the present invention;
FIG. 4 is a front enlarged sectional view of the third connecting column and the swivel ring of the present invention;
FIG. 5 is a schematic view of a partially enlarged structure of the upper end of the middle track control structure (the second connecting wire and the third connecting wire penetrate through and penetrate into the first surface of the inverted U-shaped fixing piece) according to the present invention;
FIG. 6 is a schematic view of the enlarged structure of the upper part of the middle track control structure (the first surface of the inverted U-shaped fixing piece through which the second connecting wire and the third connecting wire penetrate and penetrate) viewed from the right side;
fig. 7 is a schematic view of a partially enlarged structure of the upper end of the middle trajectory control structure (2 second connecting wires and 2 third connecting wires are provided, the second connecting wires penetrate out of and penetrate into the first surface and the second surface of the inverted U-shaped fixing piece, and the third connecting wires penetrate out of and penetrate into the first surface and the second surface of the inverted U-shaped fixing piece);
fig. 8 is a schematic view of the enlarged structure of the upper end of the middle track control structure (2 second connecting wires and 2 third connecting wires are provided, the second connecting wires penetrate out of and penetrate into the first surface and the second surface of the inverted U-shaped fixing piece, and the third connecting wires penetrate out of and penetrate into the first surface and the second surface of the inverted U-shaped fixing piece) viewed from the right side;
FIG. 9 is a sectional view of a partially enlarged front view of the middle trajectory control structure of the present invention (2 second connecting wires and 2 third connecting wires are provided, the second connecting wires penetrate and penetrate the first and second surfaces of the inverted U-shaped fixing piece, and the third connecting wires penetrate and penetrate the first and second surfaces of the inverted U-shaped fixing piece);
FIG. 10 is a sectional view of the track control structure (the second connecting wire and the third connecting wire penetrate and penetrate the planar fixing piece) according to the present invention;
FIG. 11 is an enlarged view of the placement structure of the present invention;
FIG. 12 is an enlarged cross-sectional view of the water feeding structure of the present invention;
FIG. 13 is an enlarged cross-sectional view of the bottom end of the storage bottle of the present invention;
in the figure, 11, a placing table; 12. a vertical rod; 13. a horizontal bar; 14. a connecting ring; 15. a connecting cap; 16. a third connecting column; 21. a connecting hook; 22. a stationary ring; 23. a first connecting column; 231. a circular fixing plate; 24. a second connecting column; 241. a circular ring shaped plate; 242. an independent through-hole; 25. a first connecting wire; 26. a second connecting wire; 27. a third connecting wire; 28. an inverted U-shaped fixing sheet; 281. a first side; 282. a second face; 29. a sample collection tube; 210. an adhesive tape; 211. a planar fixing sheet; 3. an animal activity barrel; 31. storing the water bottle; 32. a water feeding pipe; 33. a blocking sheet; 34. and connecting ropes.
Detailed Description
The technical solutions in the embodiments of the present invention will be described in detail below with reference to specific embodiments, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, rather than all embodiments, and those skilled in the art can easily understand other advantages and effects of the present invention from the disclosure in the specification. The utility model discloses can also implement or use through other different concrete implementation manners, under the condition of conflict-free, the characteristics in following embodiment and the embodiment can make up each other, based on the embodiment in the utility model, all other embodiments that the ordinary skilled in the art obtained under the prerequisite of not making creative work all belong to the scope of protection of the utility model.
Example 1
Referring to fig. 1-13, a device for recording the waking activity of the micro-dialysis in the brain of a rodent, comprises an animal activity structure and a placement structure for placing the animal activity structure; a track control structure for accommodating a fixed pipeline on the body of the animal is arranged above the animal moving structure, and the track control structure is movably connected with the placing structure through a connecting structure; when the animal moves in the animal moving structure in the mode, the pipelines which are fixed in the track control structure and are positioned on the animal body can rotate along with the movement of the animal, and the pipelines cannot be wound or knotted. The utility model discloses can effectively practice thrift the cost of manufacture, and convenient operation, the practicality is strong.
The placing structure is an iron stand platform which comprises a placing platform 11, a vertical rod 12 arranged at a first end of the placing platform 11 and a horizontal rod 13 perpendicular to the vertical rod 12; the horizontal rod 13 and the vertical rod 12 are movably connected through a connecting assembly; the animal moving structure is placed at the upper end of the placing table 11 in the mode, the distance between the horizontal rod 13 and the placing table 11 and the angle between the horizontal rod 13 and the vertical rod 12 are adjusted, and the track control structure is effectively connected through the connecting structure so as to ensure the proper distance between the animal moving structure and the horizontal rod 13. This arrangement facilitates adjustment of the height and angle at which the horizontal bar 13 is located.
The connecting assembly comprises a connecting ring 14 arranged at the first end of the horizontal rod 13 and a threaded cap arranged at one side of the connecting ring 14; one side of the connecting ring 14 is provided with a threaded hole for the threaded cap to extend into; the effect of connecting the horizontal rod 13 and the vertical rod 12 is achieved by the screw cap protruding into the threaded hole. The connection mode is convenient to operate, and the angle between the horizontal rod 13 and the vertical rod 12 can be effectively adjusted.
The track control structure comprises a rotating ring for fixing the probe plastic tube and a fixing structure which is arranged at the lower end of the rotating ring and is used for connecting an animal; the fixing structure comprises a connecting wire connected with the swivel, a connecting hook 21 arranged at the lower end of the connecting wire, and a fixing ring 22 fixed on the animal body; the fixing ring 22 is hung on the connecting hook 21; in this way the collar 22 is secured to the animal and the probe plastic tube is secured to the swivel and the switch is secured to the lower end of the horizontal bar 13 by a connecting structure. The device effectively meets the function of recording the brain microdialysis of the conscious and freely moving animals.
The swivel comprises a first connecting column 23 and a second connecting column 24 positioned outside the first connecting column 23, the second connecting column 24 can relatively rotate relative to the first connecting column 23, and the second connecting column 24 cannot be separated from the first connecting column 23 in the relative rotation process; the lower end of the second connecting column 24 is fixedly connected with a connecting wire; this arrangement ensures that the second connecting stud 24 and connecting wires can move with the movement of the animal when the animal is moved.
A circular fixing plate 231 is fixedly arranged on the outer side wall of the first connecting column 23, and a circular groove for the fixing plate to extend into and effectively rotate is arranged on the inner side wall of the second connecting column 24; this kind of setting effectively guarantees that second spliced pole 24 can take place relative rotation relative to first spliced pole 23, and second spliced pole 24 can not take place to separate with first spliced pole 23 in rotatory process.
The outer side wall of the second connecting column 24 is provided with a circular plate 241 for fixing a probe plastic tube, and the upper end and the lower end of the circular plate 241 are provided with independent through holes 242; during the use, inflow and outflow pipeline are from animal end fixed connection respectively in independent through-hole 242, and when the animal position changed, it took place the rotation and made the relative first spliced pole 23 of second spliced pole 24 rotate to drive inflow and outflow pipeline, effectively avoided the phenomenon that different pipelines in independent through-hole 242 took place to twine and tie a knot. 2 circular ring-shaped plates 241 are respectively arranged at the upper end and the lower end of the outer side of the second connecting column 24; at least 2 independent through holes 242 are arranged in the single circular ring plate 241; this arrangement meets the need for effective separation of the pipelines in this experiment.
The connecting wires comprise a first connecting wire 25 arranged at the lower end of the second connecting column 24, and a second connecting wire 26 and a third connecting wire 27 which are symmetrically arranged at the lower end of the first connecting wire 25; the upper ends of the second connecting wire 26 and the third connecting wire 27 meet at a point and are connected with the first connecting wire 25, and the lower ends of the second connecting wire 26 and the third connecting wire 27 meet at a point and are connected with the connecting hook 21; the total division and the arrangement of the second connecting wire 26 and the third connecting wire 27 in a parallel mode effectively ensure the stability of the connecting wires in the free movement process of the animals.
A fixing piece is arranged at the junction point of the second connecting wire 26 and the third connecting wire 27 close to the upper end, and a sample collecting pipe 29 for collecting liquid seeped from the animal body is movably arranged at the fixing piece; when the device is used, a sample is collected every 20 minutes, and the sample collection pipe 29 is fixed in position and is easy to collect, take and replace. The sample collection tube 29 is configured to have a thin upper end and a wide lower end, so that the liquid in the sample collection tube 29 is prevented from being pumped out. The fixing sheet is set as an inverted U-shaped fixing sheet 28, the position of the inverted U-shaped fixing sheet 28 is arranged on the second connecting wire 26 and the third connecting wire 27 to arch, the first connecting wire 25 is fixed at the joint end of the inverted U-shaped fixing sheet 28, and the second connecting wire 26 and the third connecting wire 27 respectively penetrate out of and penetrate into the first surface 281 and/or the second surface 282 of the inverted U-shaped fixing sheet 28; this arrangement can ensure the stability of the inverted U-shaped fixing piece 28 in fixing on the connecting wire well.
The connecting structure is a third connecting column 16 arranged at the lower end of the horizontal rod 13, a groove for the third connecting column 16 to extend into is arranged at the upper end of the first connecting column 23, and threads matched with each other are arranged on the outer side wall of the third connecting column 16 and the inner side wall of the groove. The purpose of connecting the trajectory control structure to the horizontal bar 13 is achieved by connecting the first connecting column 23 and the third connecting column 16. The rotating ring is opposite to the center of the animal movable barrel 3. Alternatively, the connecting structure is a clamp used in the prior art, and directly clamps the horizontal rod 13 and the first connecting column 23 during use.
The animal movable structure is an animal movable barrel 3 with a round bottom end, the animal movable barrel 3 is placed on the placing table 11, and a water feeding structure is further arranged on one side of the animal movable barrel 3 away from the vertical rod; this arrangement effectively ensures the free movement and survival requirements of the animals in the animal activity barrel 3.
The water feeding structure comprises a water storage bottle 31 with a bottle cap at the upper end and a water feeding pipe 32 arranged at the bottom end of the water storage bottle 31; a blocking sheet 33 for preventing water from continuously flowing into the water feeding pipe 32 is arranged at the bottom end of the water storage bottle 31; the water in the storage water bottle 31 is controlled whether to continue flowing to the water feeding pipe 32 or not by manually pulling the barrier sheet 33. The upper end of the water storage bottle 31 is provided with a connecting rope 34 which is fixed on the animal movable barrel 3. The outer side wall of the water storage bucket is provided with scales for displaying water capacity. Or the water feeding structure directly adopts the water feeding structure in the prior art.
Example 2
Referring to fig. 5 to 6, the present embodiment adds the following technical features on the basis of embodiment 1: the second connecting wire 26 and the third connecting wire 27 are provided in 1 number, respectively, and penetrate through and into the first side 281 or the second side 282 of the inverted U-shaped fixing piece 28, respectively. An adhesive tape 210 for fixing the second connecting wire 26 and the third connecting wire 27 is provided on the second connecting wire 26 and the third connecting wire 27 at the lower end of the inverted U-shaped fixing piece 28 to realize stable pumping in and out of the liquid.
Example 3
The present embodiment is different from embodiment 2 in technical features: the second attachment wire 26 passes through and into the first side 281 of the inverted U-shaped anchor 28 and the third attachment wire 27 passes through and into the second side 282 of the inverted U-shaped anchor 28. The others are consistent with the technical features of embodiment 2, and are not described herein again.
Example 4
Referring to fig. 7 to 9, the present embodiment adds the following technical features on the basis of embodiment 1: 2 of the second connecting wire 26 and the third connecting wire 27 are provided, respectively, the second connecting wire 26 passing through and penetrating the first face 281 and the second face 282 of the inverted U-shaped fixing piece 28, and the third connecting wire 27 passing through and penetrating the first face 281 and the second face 282 of the inverted U-shaped fixing piece 28.
Example 5
The present embodiment is different from embodiment 1 in technical features: the metal swivel ring of Harvard/Instech Stainless Steel rotors which is currently used is directly adopted to meet the use habit of experimenters, and the cost can be greatly reduced by only using the metal swivel ring. The connecting structure adopts the clamps used in the prior art, clamps the horizontal rod 13 and the fixing piece positioned on the metal swivel during use, and clamps the horizontal rod 13 and the fixing piece by the clamps without influencing the rotation of the metal swivel relative to the horizontal rod 13.
Other technical features in this embodiment are the same as those in embodiment 1, and are not described herein again.
Example 6
Referring to fig. 10, the technical features of the present embodiment are as follows: the fixing piece is set to be the plane fixing piece 211, the sample collection pipe 29 directly adopts the existing 1000 mL gun head, and the lower end of the gun head is sealed, so that the cost is saved to the maximum extent, and the requirement of sample collection can be met by the gun head. The second connecting wire 26 and the third connecting wire 27 penetrate through the upper end of the plane fixing piece 211 and penetrate out of the lower end of the plane fixing piece 211; the provision of the planar fixing piece 211 can simplify the steps of manufacturing the apparatus since the total amount of the sample is small at the time of collection.
Other technical features in this embodiment are the same as those in embodiment 1, and are not described herein again.
The above description of the embodiments is only intended to illustrate the present invention. It should be noted that, for those skilled in the art, without departing from the principle of the present invention, several modifications can be made to the present invention, and these modifications will fall within the protection scope of the claims of the present invention.
Claims (10)
1. A waking activity device for rodent intracerebral microdialysis recording comprises an animal activity structure and a placement structure for placing the animal activity structure; the device is characterized in that a track control structure used for containing a fixed pipeline on an animal body is arranged above the animal moving structure, and the track control structure is movably connected with the placing structure through a connecting structure.
2. The rodent brain microdialysis recording waking activity device according to claim 1, characterized in that the placing structure is provided as an iron stand, which includes a placing table, a vertical rod provided at a first end of the placing table, and a horizontal rod perpendicular to the vertical rod; the horizontal rod and the vertical rod are movably connected through a connecting component.
3. The rodent brain microdialysis recording conscious activity device according to claim 1 wherein the trajectory control structure comprises a swivel for fixing the probe plastic tube and a fixing structure for connecting the animal provided at the lower end of the swivel; the fixing structure comprises a connecting wire connected with the swivel, a connecting hook arranged at the lower end of the connecting wire and a fixing ring fixed on the animal body; the fixing ring is hung on the connecting hook.
4. The rodent brain microdialysis recording waking activity device according to claim 3, characterized in that the swivel comprises a first connecting post, a second connecting post located outside the first connecting post, the second connecting post being capable of relative rotation with respect to the first connecting post and the second connecting post not being separated from the first connecting post during the relative rotation.
5. The apparatus for waking up a rodent brain microdialysis recording according to claim 4, wherein a circular fixing plate is fixedly arranged on the outer side wall of the first connecting column, and a circular groove for the fixing plate to extend into and effectively rotate is arranged on the inner side wall of the second connecting column.
6. The device for waking up in rodent brain microdialysis recording according to claim 3, wherein the outside wall of the second connecting column is provided with a circular plate for fixing the probe plastic tube, and the upper and lower ends of the circular plate are provided with independent through holes.
7. The rodent brain microdialysis recording waking activity device according to claim 3, characterized in that the connecting wire includes the first connecting wire set at the lower end of the second connecting pole, the second connecting wire and the third connecting wire set symmetrically at the lower end of the first connecting wire; the upper ends of the second connecting wire and the third connecting wire are intersected at one point and are connected with the first connecting wire, and the lower ends of the second connecting wire and the third connecting wire are intersected at one point and are connected with the connecting hook.
8. The rodent brain microdialysis recording waking activity device according to claim 7, characterized in that a stator is set up at the junction of the second connecting wire and the third connecting wire near the upper end, a sample collecting tube for collecting the liquid exuded from the animal body is set up actively at the stator; the fixing sheet is an inverted U-shaped fixing sheet or a plane fixing sheet.
9. The rodent brain microdialysis recording waking activity device according to claim 8, characterized in that the second and third connecting wire set the inverted U-shaped stator position arch radian, the first connecting wire fixed on the combination end of the inverted U-shaped stator, the second and third connecting wire respectively through and into the first and/or second side of the inverted U-shaped stator.
10. The device for waking up a rodent brain microdialysis recording according to claim 1, wherein the connecting structure is a third connecting column arranged at the lower end of the horizontal rod, a groove for the third connecting column to extend into is arranged at the upper end of the first connecting column, and mutually matching threads are arranged on the outer side wall of the third connecting column and the inner side wall of the groove.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202121027247.4U CN213465450U (en) | 2021-05-14 | 2021-05-14 | Waking activity device for rodent intracerebral microdialysis recording |
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| CN202121027247.4U CN213465450U (en) | 2021-05-14 | 2021-05-14 | Waking activity device for rodent intracerebral microdialysis recording |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112971864A (en) * | 2021-05-14 | 2021-06-18 | 中国医学科学院医学实验动物研究所 | Animal brain microdialysis recording device for waking and freely moving |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112971864A (en) * | 2021-05-14 | 2021-06-18 | 中国医学科学院医学实验动物研究所 | Animal brain microdialysis recording device for waking and freely moving |
| CN112971864B (en) * | 2021-05-14 | 2022-02-18 | 中国医学科学院医学实验动物研究所 | Animal brain microdialysis recording device for waking and freely moving |
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