CN213423196U - Incubation device and immunoassay analyzer - Google Patents
Incubation device and immunoassay analyzer Download PDFInfo
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- CN213423196U CN213423196U CN202021564221.9U CN202021564221U CN213423196U CN 213423196 U CN213423196 U CN 213423196U CN 202021564221 U CN202021564221 U CN 202021564221U CN 213423196 U CN213423196 U CN 213423196U
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- heating plate
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- steel ball
- incubation
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- 238000003018 immunoassay Methods 0.000 title claims abstract description 7
- 238000011534 incubation Methods 0.000 title claims description 28
- 238000010438 heat treatment Methods 0.000 claims abstract description 68
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 41
- 229910000831 Steel Inorganic materials 0.000 claims description 22
- 239000010959 steel Substances 0.000 claims description 22
- 230000001360 synchronised effect Effects 0.000 claims description 21
- 238000001514 detection method Methods 0.000 claims description 16
- 238000003780 insertion Methods 0.000 claims description 9
- 230000037431 insertion Effects 0.000 claims description 9
- 239000011324 bead Substances 0.000 claims description 6
- 238000000926 separation method Methods 0.000 claims description 4
- 230000004907 flux Effects 0.000 abstract description 2
- 230000012447 hatching Effects 0.000 abstract description 2
- 238000012031 short term test Methods 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 230000008859 change Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000004321 preservation Methods 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 230000006978 adaptation Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 238000003317 immunochromatography Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000008447 perception Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
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Abstract
The utility model relates to a medical science detecting instrument technical field, more specifically say, relate to an incubate device and immunoassay appearance, and the structure of hatching includes carousel, drive structure and constant temperature heating structure, the carousel has a plurality of draw-in grooves, can detect many reagent cards simultaneously, does not receive the restriction and the restraint of environment, has realized constant temperature, high flux, simple and short-term test.
Description
Technical Field
The utility model relates to a medical science detecting instrument technical field, more specifically say, relate to an incubation device and immunoassay appearance.
Background
Compared with other clinical diagnosis methods, the immunochromatography technology has the characteristics of flexibility, rapidness and simple operation, so that the market space is large and the development prospect is good.
In order to guarantee the effect of chromatographic reaction, reply changeable ambient temperature, need possess on the check out test set and incubate the device, the incubation device among the prior art mainly has plate structure and disk structure. The plate-type structure is relatively simple, stable and reliable, but the space is limited, and the number of the incubated reagent cards is small, so that the improvement of the test flux is not facilitated; the disc structure overcomes the problem of small test quantity of the plate structure, but the existing disc structure mostly independently sets incubation positions, so that the efficiency is low, and the incubation time is different from the actual reaction time, so that the detection result is inaccurate; and a few incubation devices in the form of heat preservation pots are adopted, so that the volume of the instrument is increased and the occupied space is occupied due to the existence of the heat preservation pots. The development direction of modern instruments is simple, accurate and miniaturized, so that a miniaturized instrument which achieves an accurate measurement effect by using a simple device is the demand of modern medical treatment.
SUMMERY OF THE UTILITY MODEL
In order to solve the problem that above-mentioned detection efficiency is low, the testing result is inaccurate and the shared space of carousel is big, the utility model provides an incubate device and immunoassay appearance, concrete scheme is as follows:
the utility model provides an incubation device of analysis appearance, includes carousel, drive structure and constant temperature heating structure, the drive structure with the axle center of carousel links to each other, constant temperature heating structure includes annular heating plate, the heating plate is installed the below of carousel.
Preferably, the turntable comprises a plurality of radially distributed pressure plate blocks, the pressure plate blocks are arranged at intervals, and a clamping groove is formed between the two pressure plate blocks and used for fixing the inserted reagent card.
Preferably, be equipped with the mounting hole on the draw-in groove, install the location pearl that is used for supplementary fixed reagent card in the mounting hole, the location pearl is including the shell that has spacing hole, install the spring in spacing hole bottom, be located the steel ball of spring upper end and install the apron on the shell, the apron covers partial steel ball, the shape of steel ball and the bottom shape looks adaptation of reagent card, when the reagent card inserts the draw-in groove bottom, steel ball embedding reagent card bottom, through the supplementary fixed action of location pearl to the reagent card, prevent when the carousel is rotatory, the reagent card is because centrifugal force is thrown away, and then has increased the stability and the fault-tolerant rate of instrument.
Optionally, a mounting hole is formed in the clamping groove, a spring, a steel ball positioned at the upper end of the spring and a cover plate arranged on the reaction disc are arranged in the mounting hole, the cover plate covers part of the steel ball, the shape of the steel ball is matched with the shape of the bottom of the reagent card, and the reagent card can be prevented from being thrown out due to centrifugal force when the rotary disc rotates.
Preferably, the drive structure includes rotating shaft subassembly, hold-in range and motor, rotating shaft subassembly one end is connected the axle center of carousel, the other end is connected the hold-in range, the hold-in range cover is established on the output shaft of motor, the motor is installed in the frame.
Preferably, the rotating shaft assembly comprises a bearing, a pulley shaft, a bearing sleeve and a synchronous pulley, the bearing is sleeved outside the pulley shaft, the bearing is located in the bearing sleeve and coaxially arranged with the bearing sleeve, and the synchronous pulley is located at the lower end of the bearing sleeve and connected with the synchronous belt.
Preferably, the rotating shaft assembly further comprises a positioning structure, the positioning structure is connected with the bearing sleeve and provided with a disc joint and a positioning pin, the disc joint and the positioning pin are both connected with the rotating disc in a matched mode, the positioning accuracy of the rotating disc can be improved, and the disc joint and the positioning pin can be one or more.
Preferably, the constant temperature heating structure still includes hot plate support, hot plate and temperature sensor, hot plate support lower extreme is fixed in the frame, the upper end with bottom surface is connected under the hot plate, heating plate and temperature sensor are all installed on the hot plate, temperature sensor is used for the change of perception hot plate temperature and feeds back to the system, keeps the constancy of temperature through system control, the heat that the heating plate produced passes through the hot plate transmits the carousel makes the carousel keep constant temperature.
Preferably, the heating plate is annular, and the heating plate is mounted on the lower surface of the heating plate.
Preferably, an annular groove is opened on a lower surface of the heating plate, and the heating sheet is fitted in the annular groove.
Optionally, the heating sheet is directly adhered to the lower surface of the heating plate.
The constant-temperature heating structure can improve the utilization efficiency of heat, saves energy and is beneficial to temperature control.
Preferably, the heating plate is supported by a heating plate support, and the upper surface of the heating plate is horizontally aligned with the lower surface of the turntable and vertically overlapped.
Preferably, the incubation device further comprises a card insertion detection device, the card insertion detection device is installed on the lower surface of the heating plate, the central line position coincides with the central line of the turntable, and the card insertion detection device is aligned to the card insertion opening and used for detecting whether a reagent card is inserted.
Preferably, the incubation device further comprises an encoding disc, the encoding disc is provided with a resetting blocking piece and a plurality of positioning blocking pieces which are uniformly distributed on the encoding disc, the encoding disc is located below the rotary disc and synchronously rotates with the rotary disc, and the positioning blocking pieces correspond to the rotary disc reagent card in position.
More preferably, the incubation device further comprises a detection sensor, wherein the detection sensor is mounted on the frame and comprises a first position sensor and a second position sensor, the first position sensor and the positioning baffle of the coding disc are positioned on the same horizontal plane, and the second position sensor and the reset baffle of the coding disc are positioned on the same horizontal plane.
Has the advantages that:
the utility model discloses ingenious utilization space makes whole hatching device compact, the operation high-efficient.
1. The annular constant-temperature heating structure is arranged at the bottom of the rotary table, so that the space occupied by the constant-temperature heating structure is reduced; because the heating plate and the heating plate are both annular, heat can be evenly distributed on the turntable.
2. The utility model discloses a setting of hot plate and heating plate replaces traditional heat preservation pot, and not only the volume is littleer, and has reduced the requirement to structure and hardware, makes whole device simpler, is applicable to the miniatur instrument.
3. Set up the clamp plate piece through radiating on the carousel, form the draw-in groove naturally between two clamp plate pieces, can realize the loading of more reagent cards, set up spacing hole on the draw-in groove, guarantee that the reagent card is stable not landing, when saving space, fixed reagent card.
4. Through the position at code wheel location separation blade reaction reagent dish, set up the separation blade reaction carousel that resets below the code wheel and whether get back to initial position, code wheel and sensor are whole to be installed in the space of carousel below, utilize limited space, reach the efficient cooperation.
Drawings
FIG. 1: structure diagram of the incubation device;
FIG. 2: partial structure diagram of the rotary table;
FIG. 3: a driving structure schematic diagram;
FIG. 4: a schematic view of a constant temperature heating structure;
FIG. 5: schematic diagram of positioning bead structure.
The reference numbers in the figures denote: the device comprises a rotary disc 1, a pressing plate block 11, a clamping groove 12, a mounting hole 13, a spring 131, a steel ball 132, a cover plate 133, a limiting hole 134, a shell 135, a driving structure 2, a rotating shaft assembly 21, a bearing 211, a belt wheel shaft 212, a bearing sleeve 213, a synchronous belt pulley 214, a synchronous belt 22, a motor 23, a constant-temperature heating structure 3, a heating plate support 31, a heating plate 32, a temperature sensor 33, a heating plate 34, a card insertion detection device 35, a positioning structure 4, a disc joint 41, a positioning pin 42, an encoding disc 5, a positioning baffle 51, a reset baffle 52, a detection sensor 6, a first position sensor 61 and a second position sensor 62.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
As shown in figure 1, the incubation device of the analyzer comprises a rotary table 1, a driving structure 2 and a constant-temperature heating structure 3, wherein the driving structure 2 is connected with the axis of the rotary table 1, and the constant-temperature heating structure 3 is arranged below the rotary table 1.
As shown in fig. 2, a plurality of radially distributed pressure plates 11 are mounted on the turntable, and the pressure plates 11 are arranged at intervals to form clamping grooves 12 for limiting the inserted reagent card.
As shown in fig. 2 and 5: the clamping groove 12 is provided with a mounting hole 13, a positioning bead for assisting in fixing the reagent card is mounted in the mounting hole 13, and the positioning bead comprises a shell 135 with a limiting hole 134, a spring 131 mounted at the bottom of the limiting hole, a steel ball 132 positioned at the upper end of the spring 131 and a cover plate 133 mounted on the shell. The spring 131 is in a compressed state, the cover plate 133 covers part of the steel balls 132, the shape of the steel balls 132 is matched with the groove on the reagent card (the steel balls 132 are matched with the shape of the bottom of the reagent card), and when the reagent card is inserted into the bottom of the card slot 12, the steel balls 132 are embedded into the bottom of the reagent card. Through the auxiliary fixing effect of the positioning beads on the reagent card, the reagent card is prevented from being thrown out due to centrifugal force when the rotary table 1 rotates, and then the stability and fault tolerance of the instrument are increased.
As shown in fig. 1, the driving structure 2 includes a rotating shaft assembly 21, a synchronous belt 22 and a motor 23, one end of the rotating shaft assembly 21 is connected to the center of the turntable 1, the other end is connected to the synchronous belt 22, the synchronous belt 22 is sleeved on an output shaft of the motor 23, and the motor 23 is installed on the rack.
As shown in fig. 3, the rotating shaft assembly 21 includes a bearing 211, a pulley shaft 212, a bearing sleeve 213, and a synchronous pulley 214, the bearing 211 is sleeved outside the pulley shaft 212, the bearing 211 is located in the bearing sleeve 213 and is coaxially disposed with the bearing sleeve 213, and the synchronous pulley 214 is installed at the lower end of the bearing sleeve 213 and is connected to the synchronous belt 22.
The rotating shaft assembly further comprises a positioning structure 4, the positioning structure 4 is connected with the sleeve 213 and is provided with a disc joint 41 and a positioning pin 42, the disc joint 41 and the positioning pin 42 are located on the upper surface of the positioning structure 4 and are connected with the rotating disc 1 for installing the rotating disc and improving the positioning accuracy of the rotating disc, and one or more disc joints 41 and one or more positioning pins 42 can be provided.
As shown in fig. 4, the constant temperature heating structure 3 includes a heating plate support 31, a heating plate 32, a temperature sensor 33, a heating plate 34, the lower end of the heating plate support 31 is fixed on the frame, the upper end is connected with the lower bottom surface of the heating plate 32, the temperature sensor 33 is further installed on the lower bottom surface of the heating plate 32, the temperature sensor 33 is used for sensing the temperature change of the heating plate and feeding back the temperature change to the system, the temperature is kept constant through system control, the heating plate 34 is installed on the lower bottom surface of the heating plate 32, the heat generated by the heating plate 34 is transmitted to the turntable 1 through the heating plate 32, so that the turntable 1 is.
The incubation device further comprises a plug-in card detection device 35, the plug-in card detection device 35 is installed on the lower surface of the heating plate 32, the center line penetrates through the circle center of the turntable and is aligned with the plug-in card port for detecting whether a reagent card is inserted.
The heating plate 34 is ring-shaped, so that the whole reagent card can be in a constant temperature environment. The heating plate 34 can be directly adhered to the lower surface of the heating plate 32, an annular groove can also be formed in the heating plate 32, and the heating plate 34 is embedded in the annular groove.
As shown in fig. 3, the incubation device further includes a code wheel 5, the code wheel 5 includes a positioning stop piece 51 and a reset stop piece 52, and the code wheel 5 is located below the synchronous pulley 214 and rotates synchronously with the synchronous pulley 214.
The incubation device further comprises a detection sensor 6, wherein the detection sensor 6 is mounted on the frame and comprises a first position sensor 61 and a second position sensor 62, the first position sensor 61 and the positioning baffle 51 of the coding disc 5 are positioned on the same horizontal plane, and the second position sensor 62 and the reset baffle 52 of the coding disc 5 are positioned on the same horizontal plane.
The utility model discloses during the use, at first heat carousel 1 with system control constant temperature heating structure 3, through the constancy of temperature sensor 33 control heating board 32 temperature, system control carousel 1 turns to the card position of inserting after that, inserts the reagent card, can guarantee like this to begin to hatch when inserting the reagent card, guarantees that the incubation time of reagent card is accurate.
Then, the inserted card detecting device 35 detects the insertion of the reagent card, when the motor 23 drives the rotating shaft assembly 21 to rotate through the synchronous belt 22, the rotating shaft assembly 21 drives the rotary disc 1 to move the reagent card to each working position, when the rotary disc 1 rotates, the encoding disc 5 rotates synchronously, when the positioning blocking piece 51 of the encoding disc 5 rotates to block the second position sensor 62, the signal of the second position sensor 62 is cut off, the position of the rotary disc can be fed back, when the reset blocking piece 52 rotates to block the first position sensor 61, the signal of the first position sensor 61 is cut off, and whether the rotary disc returns to the initial position or not can be fed back.
In the embodiment, the annular constant-temperature heating structure 3 is arranged at the bottom of the turntable 1, so that the space occupied by the constant-temperature heating structure is reduced; the pressure plate blocks 11 are arranged on the rotary table 1 in a radiation mode, the clamping grooves 12 are naturally formed between the two pressure plate blocks, loading of more reagent cards can be achieved, the mounting holes 13 are formed in the clamping grooves, the reagent cards are guaranteed to be stable and not to slide off, and the reagent cards are fixed while the space is saved; the position of the rotary disc 1 is reflected by the positioning baffle 51 of the coded disc 5, the reset baffle 52 is arranged below the coded disc 5 to reflect whether the rotary disc 1 returns to the initial position, the coded disc 5 and the sensor 6 are wholly arranged in a gap below the rotary disc, and efficient matching is achieved by utilizing limited space.
This embodiment, utilize above structure, ingenious utilization space makes whole incubation device compact, the operation high efficiency.
The upper 12 of the card slot in this embodiment is provided with the mounting hole 13, so that the spring 131, the steel ball 132 positioned at the upper end of the spring and the cover plate 133 installed on the reaction disk can be directly installed in the mounting hole 13 without the auxiliary action of the positioning ball, the cover plate 133 covers part of the steel ball 132, and the shape of the steel ball 132 is matched with the shape of the bottom of the reagent card.
Claims (10)
1. The utility model provides an incubation device, its characterized in that, includes carousel, drive structure and constant temperature heating structure, the drive structure with the axle center of carousel links to each other, constant temperature heating structure includes annular heating plate, the heating plate is installed the below of carousel.
2. The incubation apparatus of claim 1, wherein the carousel includes a plurality of radially spaced pressure plates spaced apart to define a slot therebetween for receiving an inserted reagent card.
3. The incubation device according to claim 2, wherein the slot is provided with a mounting hole, a positioning bead for assisting in fixing the reagent card is mounted in the mounting hole, the positioning bead comprises a housing with a limiting hole, a spring mounted at the bottom of the limiting hole, a steel ball positioned at the upper end of the spring, and a cover plate mounted on the housing, the cover plate covers part of the steel ball, and the shape of the steel ball is matched with the shape of the bottom of the reagent card.
4. The incubation device according to claim 2, wherein the clamping groove is provided with a mounting hole, a spring, a steel ball positioned at the upper end of the spring and a cover plate arranged on the reaction plate are arranged in the mounting hole, the cover plate covers part of the steel ball, and the shape of the steel ball is matched with the shape of the bottom of the reagent card.
5. The incubation device according to any one of claims 1 to 4, wherein the driving structure comprises a rotating shaft assembly, a synchronous belt and a motor, one end of the rotating shaft assembly is connected with the axis of the turntable, the other end of the rotating shaft assembly is connected with the synchronous belt, the synchronous belt is sleeved on an output shaft of the motor, and the motor is mounted on the frame;
the rotating shaft assembly comprises a bearing, a pulley shaft, a bearing sleeve, a synchronous pulley and a positioning structure, the bearing sleeve is arranged outside the pulley shaft, the pulley shaft is located in the bearing sleeve and coaxially arranged with the bearing sleeve, the synchronous pulley is arranged on the bearing sleeve, the synchronous pulley is connected with the synchronous belt, the positioning structure is connected with the bearing sleeve and provided with a disc joint and a positioning pin, and the disc joint and the positioning pin are both matched and connected with the turntable.
6. The incubation device according to any one of claims 1 to 4, wherein the constant temperature heating structure further comprises a heating plate support, a heating plate and a temperature sensor, the lower end of the heating plate support is fixed on the frame, the upper end of the heating plate support is connected with the lower bottom surface of the heating plate, and the heating plate and the temperature sensor are both mounted on the heating plate.
7. The incubation apparatus of claim 6, wherein the heating plate has an annular groove formed in a lower surface thereof, and the heating plate is fitted into the annular groove.
8. The incubation apparatus of claim 6, further comprising a card insertion detection device mounted on the lower surface of the heater plate with a centerline coincident with the centerline of the carousel and aligned with the card insertion opening for detecting the insertion of a reagent card.
9. The incubation device according to any one of claims 1 to 4, further comprising an encoding disk and a detection sensor, wherein the encoding disk is provided with a reset block and a plurality of positioning blocks uniformly distributed on the encoding disk, and the encoding disk is positioned below the rotating disk and rotates synchronously with the rotating disk; the detection sensor is installed on the rack and comprises a first position sensor and a second position sensor, the first position sensor and the positioning separation blade of the coding disc are located on the same horizontal plane, and the second position sensor and the reset separation blade of the coding disc are located on the same horizontal plane.
10. An immunoassay analyzer, wherein the immunoassay analyzer is provided with the incubation device according to any one of claims 1 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021564221.9U CN213423196U (en) | 2020-07-31 | 2020-07-31 | Incubation device and immunoassay analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021564221.9U CN213423196U (en) | 2020-07-31 | 2020-07-31 | Incubation device and immunoassay analyzer |
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| Publication Number | Publication Date |
|---|---|
| CN213423196U true CN213423196U (en) | 2021-06-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021564221.9U Active CN213423196U (en) | 2020-07-31 | 2020-07-31 | Incubation device and immunoassay analyzer |
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| CN (1) | CN213423196U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115184592A (en) * | 2022-06-24 | 2022-10-14 | 普迈德（北京）科技有限公司 | Immunoassay detection equipment and detection method |
-
2020
- 2020-07-31 CN CN202021564221.9U patent/CN213423196U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115184592A (en) * | 2022-06-24 | 2022-10-14 | 普迈德（北京）科技有限公司 | Immunoassay detection equipment and detection method |
| CN115184592B (en) * | 2022-06-24 | 2023-09-29 | 普迈德（北京）科技有限公司 | Immunoassay detection equipment and detection method |
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| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 400037 1st-4th floor, building 30, No.6 Taikang Road, Zone C, Jianqiao Industrial Park, Dadukou District, Chongqing Patentee after: Zhongyuan Huiji Biotechnology Co.,Ltd. Address before: 400037 1st-4th floor, building 30, No.6 Taikang Road, Zone C, Jianqiao Industrial Park, Dadukou District, Chongqing Patentee before: CHONGQING ZHONGYUAN HUIJI BIOTECHNOLOGY Co.,Ltd. |
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| CP03 | Change of name, title or address |
Address after: No. 45 Shilin Avenue, Tiaodeng Town, Dadukou District, Chongqing 400082 Patentee after: Zhongyuan Huiji Biotechnology Co.,Ltd. Country or region after: China Address before: 400037 1st-4th floor, building 30, No.6 Taikang Road, Zone C, Jianqiao Industrial Park, Dadukou District, Chongqing Patentee before: Zhongyuan Huiji Biotechnology Co.,Ltd. Country or region before: China |