CN213347877U

CN213347877U - Heparin sodium production is with removing albumen device

Info

Publication number: CN213347877U
Application number: CN202021990355.7U
Authority: CN
Inventors: 陈广英; 许悟赟; 田陈慧; 韩国栋
Original assignee: Nantong Tianrui Biotechnology Co ltd
Current assignee: Nantong Tianrui Biotechnology Co ltd
Priority date: 2020-09-14
Filing date: 2020-09-14
Publication date: 2021-06-04
Anticipated expiration: 2030-09-14

Abstract

The utility model discloses a heparin sodium production is with removing albumen device, including device main part, bull stick, stirring leaf, transparent measuring cylinder and annular tube, the inside of device main part is provided with the bull stick, and the device main part top of bull stick position department installs the motor to the pivot is installed through the shaft coupling to the output of motor, the bottom of pivot extend to the inside of device main part and with the top fixed connection of bull stick, the device main part top of motor one side is fixed with the inlet pipe, and the device main part top of motor opposite side is fixed with transparent measuring cylinder, be fixed with the separator tube on the outer wall of device main part bottom, and the internally mounted of separator tube has manual valve, the turning position department of device main part bottom all is fixed with the stabilizer blade, and inlays on the outer wall of device main part one side and has the observation window. The utility model discloses not only improved the sufficiency that removes the albumen, realized the control function to the precipitant addition amount, improved the accurate nature of removing the albumen operation moreover.

Description

Heparin sodium production is with removing albumen device

Technical Field

The utility model relates to a heparin sodium production technical field specifically is a heparin sodium production is with removing albumen device.

Background

Heparin is a mucopolysaccharide widely existing in mammal tissues, heparin sodium is a sodium salt of heparin, has the effects of anticoagulation, antithrombotic formation and blood fat regulation, also has the functions of anti-inflammation, antiallergic, antivirus, anticancer and the like, is widely used for surgery and treatment of cerebral thrombosis, myocardial infarction and the like, is regarded by attention of all countries in the world as a natural anticoagulation substance, and is also one of main export medicaments in China, a crude heparin sodium product is a traditional export product in China and plays an important role internationally, at present, the heparin sodium is mainly extracted from the mucous membrane of the small intestine of a pig, when a protein-free product and a fine product of the heparin sodium are prepared, the protein in the heparin sodium is usually removed by using a precipitator, and therefore a protein removing device is required.

The protein removing devices on the market are various and can basically meet the use requirements of people, but certain defects still exist, and the specific problems are as follows.

(1) When the existing protein removing device is used, the contact between the heparin sodium mixed solution and the precipitator is not uniform enough, so that the protein removing is not sufficient, and the improvement space exists.

(2) The existing deproteinizing device is inconvenient to control the amount of added precipitator when in use, and the activity of heparin sodium can be influenced by too little or too much addition amount, so certain defects exist.

(3) When the existing protein removing device is used, the precipitated protein is difficult to be removed accurately according to the amount of the heparin sodium mixed solution, so that inconvenience is brought to the protein removing work.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a heparin sodium production is with removing albumen device to it removes albumen inadequately abundant to solve to provide in the above-mentioned background art to remove albumen device when using, and the inconvenient precipitant that adds carries out accuse volume and is difficult to the problem of the accurate albumen of will deposiing of the volume of mixing liquid according to heparin sodium is detached.

In order to achieve the above object, the utility model provides a following technical scheme: a deproteinizing device for heparin sodium production, which comprises a device main body, a rotating rod, a stirring blade, a transparent measuring cylinder and an annular tube, a rotating rod is arranged in the device main body, a motor is arranged at the top end of the device main body at the position of the rotating rod, the output end of the motor is provided with a rotating shaft through a coupler, the bottom end of the rotating shaft extends into the device main body and is fixedly connected with the top end of the rotating rod, the top end of the device main body at one side of the motor is fixedly provided with a feeding pipe, a transparent measuring cylinder is fixed at the top end of the device main body at the other side of the motor, a separating tube is fixed on the outer wall of the bottom of the device main body, and a manual valve is arranged in the separation tube, support legs are fixed at the corner positions of the bottom end of the device main body, an observation window is embedded on the outer wall of one side of the device main body, and install control panel on the device main part outer wall of observation window one side, the output of the inside singlechip of control panel and the input electric connection of motor.

Preferably, all weld on the outer wall of bull stick both sides and have the stirring leaf, and the inside of stirring leaf all is provided with equidistant round hole, is convenient for mix heparin sodium mixed liquid and precipitant.

Preferably, the inside pipe that is provided with of device main part of bull stick one side, the top of pipe extends to the outside of device main part, and all is fixed with equidistant retainer plate on the outer wall of pipe, and the heparin sodium mixed liquid after the accurate protein of will removing of being convenient for is taken out.

Preferably, the device main part top outside the bull stick is fixed with the annular tube, and the bottom of annular tube all is fixed with equidistant drain pipe, is convenient for with the even inside of leading-in to heparin sodium mixed solution of precipitant.

Preferably, one side on transparent measuring cylinder top is fixed with the feed liquor pipe, all marks the scale mark that has equidistant on the outer wall of transparent measuring cylinder one side, and one side of transparent measuring cylinder bottom is fixed with the conveyer pipe, and the bottom of conveyer pipe extends to the inside of device main part and is linked together with the annular tube to the internally mounted of conveyer pipe has the control valve, is convenient for control the addition of precipitant.

Preferably, the device main part top of inlet pipe one side is fixed with the fixed plate, and the top of fixed plate is provided with U type groove, the mutual block of U type groove and retainer plate for the fixed work of pipe.

Compared with the prior art, the beneficial effects of the utility model are that: the protein removing device for producing the heparin sodium not only improves the sufficiency of protein removal, realizes the control function of the addition amount of the precipitator, but also improves the accuracy of the protein removing operation;

(1) through being provided with the bull stick, including a motor, an end cap, a controller, and a cover plate, the pivot, ring pipe and drain pipe, the even dispersion of the inside precipitant of ring pipe is opened and is discharged through the drain pipe, the even inside of mixing into the heparin sodium mixed liquid of precipitant, the motor makes its rotation through pivot drive bull stick, the bull stick drives the stirring leaf and rotates, mix the liquid to heparin sodium, the inside round hole of stirring leaf is further to mix liquid and precipitant to heparin sodium and disperse, thereby the homogeneity of the mixed liquid contact of precipitant and heparin sodium has been improved, and then the sufficiency of protein has been improved.

(2) Through being provided with transparent measuring cylinder, feed liquor pipe, scale mark, conveyer pipe and control valve, will remove the required precipitant of albumen through the feed liquor pipe and pour into the inside of transparent measuring cylinder, the addition of accessible scale mark control precipitant, then, open the control valve and make the inside precipitant of transparent measuring cylinder pass through the inside that the conveyer pipe flowed into the annular pipe to realized the control function to the precipitant addition, guaranteed the activity of heparin sodium.

(3) Through being provided with the fixed plate, U type groove, the pipe, retainer plate and observation window, the boundary of heparin sodium mixed liquid and albumen layer is observed to the accessible observation window, and the position of port under its pulling pipe adjustment, place the pipe in the inside U type groove of fixed plate again, utilize the retainer plate to fix the pipe, with external equipment and pipe connection, can take out heparin sodium mixed liquid, open the protein that makes device main part bottom and pass through the separator tube and discharge with manual valve, thereby the accurate nature of removing the albumen operation has been improved.

Drawings

Fig. 1 is a schematic sectional view of the present invention.

Fig. 2 is a schematic view of the appearance structure of the present invention.

Fig. 3 is an enlarged schematic view of the transparent measuring cylinder of the present invention.

Fig. 4 is a schematic view of the enlarged structure of the annular tube in the bottom view.

Fig. 5 is a schematic diagram of the side-view enlarged structure of the fixing plate of the present invention.

In the figure: 1. a device main body; 2. a support leg; 3. a rotating rod; 4. stirring blades; 5. a circular hole; 6. a transparent measuring cylinder; 7. a motor; 8. a rotating shaft; 9. a feed pipe; 10. a fixing plate; 11. an annular tube; 12. a conduit; 13. a stationary ring; 14. a separation tube; 15. a manual valve; 16. a control panel; 17. an observation window; 18. a liquid inlet pipe; 19. scale lines; 20. a delivery pipe; 21. a control valve; 22. a drain pipe; 23. a U-shaped groove.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-5, the present invention provides an embodiment: the utility model provides a heparin sodium production is with removing albumen device, includes device main part 1, bull stick 3, stirring leaf 4, transparent measuring cylinder 6 and annular tube 11, the inside of device main part 1 is provided with bull stick 3, and the motor 7 is installed on the device main part 1 top of bull stick 3 position department, the model of this motor 7 can be Y112M-2, and the pivot 8 is installed through the shaft coupling to the output of motor 7, the bottom of pivot 8 extend to the inside of device main part 1 and with the top fixed connection of bull stick 3.

All welded on the outer wall of 3 both sides of bull stick has stirring leaf 4, and the inside of stirring leaf 4 all is provided with equidistant round hole 5, is convenient for mix heparin sodium mixed liquid and precipitant.

A guide pipe 12 is arranged in the device main body 1 at one side of the rotating rod 3, the top end of the guide pipe 12 extends to the outside of the device main body 1, and fixing rings 13 with equal intervals are fixed on the outer wall of the guide pipe 12, so that the heparin sodium mixed solution after protein removal can be accurately extracted;

an annular pipe 11 is fixed at the top of the device body 1 outside the rotating rod 3, and drain pipes 22 with equal intervals are fixed at the bottom ends of the annular pipe 11, so that a precipitator can be uniformly led into the heparin sodium mixed solution;

a feeding pipe 9 is fixed at the top end of the device body 1 at one side of the motor 7, and a transparent measuring cylinder 6 is fixed at the top end of the device body 1 at the other side of the motor 7.

One side on the transparent measuring cylinder 6 top is fixed with feed liquor pipe 18, all marks the scale mark 19 that has the equidistant on the outer wall of transparent measuring cylinder 6 one side, and one side of transparent measuring cylinder 6 bottom is fixed with conveyer pipe 20, and the bottom of conveyer pipe 20 extends to the inside of device main part 1 and is linked together with annular pipe 11 to the internally mounted of conveyer pipe 20 has control valve 21, is convenient for control the addition of precipitant.

The top end of the device body 1 on one side of the feeding pipe 9 is fixed with a fixing plate 10, the top of the fixing plate 10 is provided with a U-shaped groove 23, and the U-shaped groove 23 is clamped with the fixing ring 13 for fixing the guide pipe 12.

Be fixed with separator tube 14 on the outer wall of device main part 1 bottom, and the internally mounted of separator tube 14 has manual valve 15, and the corner position department of device main part 1 bottom all is fixed with stabilizer blade 2, and inlays on the outer wall of device main part 1 one side and has observation window 17 to install control panel 16 on the device main part 1 outer wall of observation window 17 one side, this control panel 16's model can be DL203, the output of the inside singlechip of control panel 16 and the input electric connection of motor 7.

The working principle is as follows: when in use, a worker firstly pours the heparin sodium mixed solution to be processed into the device main body 1 through the feeding pipe 9, secondly, pours the precipitant required for removing protein into the transparent measuring tube 6 through the liquid inlet pipe 18, at the moment, the addition of the precipitant can be controlled through the scale mark 19, then, the control valve 21 is opened to make the precipitant in the transparent measuring tube 6 flow into the annular pipe 11 through the conveying pipe 20, thereby realizing the control function of the addition of the precipitant, ensuring the activity of the heparin sodium, then, the precipitant in the annular pipe 11 is uniformly dispersed and discharged through the water discharging pipe 22, the precipitant is uniformly mixed into the heparin sodium, the control motor 7 is controlled to work through the operation control panel 16, the motor 7 drives the rotating rod 3 to rotate through the rotating shaft 8, the rotating rod 3 drives the stirring vane 4 to rotate, and stirs the heparin sodium mixed solution, the round hole 5 inside the stirring blade 4 further disperses the heparin sodium mixed solution and the precipitator, thereby improving the contact uniformity of the precipitator and the heparin sodium mixed solution, thereby improving the sufficiency of protein removal, and finally, after the heparin sodium mixed solution is stood still, the protein can be layered and deposited at the bottom of the device main body 1, the boundary between the heparin sodium mixed solution and the protein layer can be observed through the observation window 17, the position of the lower port of the guide tube 12 is adjusted by pulling the guide tube 12, the guide tube 12 is placed in the U-shaped groove 23 inside the fixing plate 10, the catheter 12 is fixed by the fixing ring 13, an external device is connected with the catheter 12, the mixed liquid of heparin and sodium can be pumped out, the manual valve 15 is opened to discharge the protein at the bottom of the device main body 1 through the separation pipe 14, thereby improving the accuracy of protein removal operation and completing the work of the protein removal device for heparin sodium production.

It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims

1. The utility model provides a heparin sodium production is with removing albumen device, includes device main part (1), bull stick (3), stirring leaf (4), transparent measuring cylinder (6) and annular tube (11), its characterized in that: the device is characterized in that a rotating rod (3) is arranged inside a device main body (1), a motor (7) is installed at the top end of the device main body (1) at the position of the rotating rod (3), a rotating shaft (8) is installed at the output end of the motor (7) through a coupler, the bottom end of the rotating shaft (8) extends into the device main body (1) and is fixedly connected with the top end of the rotating rod (3), a feeding pipe (9) is fixed at the top end of the device main body (1) at one side of the motor (7), a transparent measuring cylinder (6) is fixed at the top end of the device main body (1) at the other side of the motor (7), a separating pipe (14) is fixed on the outer wall of the bottom of the device main body (1), a manual valve (15) is installed inside the separating pipe (14), supporting legs (2) are fixed at the corner positions at the bottom end of the device main body (1), and an observation window, and install control panel (16) on the device main part (1) outer wall of observation window (17) one side, the output of the inside singlechip of control panel (16) and the input electric connection of motor (7).

2. The deproteinizing device for heparin sodium production according to claim 1, which is characterized in that: the outer walls of the two sides of the rotating rod (3) are welded with stirring blades (4), and round holes (5) with equal intervals are formed in the stirring blades (4).

3. The deproteinizing device for heparin sodium production according to claim 1, which is characterized in that: the device is characterized in that a guide pipe (12) is arranged inside the device main body (1) on one side of the rotating rod (3), the top end of the guide pipe (12) extends to the outside of the device main body (1), and fixing rings (13) with equal intervals are fixed on the outer wall of the guide pipe (12).

4. The deproteinizing device for heparin sodium production according to claim 1, which is characterized in that: the top of the device main body (1) outside the rotating rod (3) is fixed with an annular pipe (11), and the bottom ends of the annular pipe (11) are fixed with drain pipes (22) at equal intervals.

5. The deproteinizing device for heparin sodium production according to claim 4, is characterized in that: one side on transparent measuring cylinder (6) top is fixed with feed liquor pipe (18), all marks scale mark (19) of equidistant on the outer wall of transparent measuring cylinder (6) one side, and one side of transparent measuring cylinder (6) bottom is fixed with conveyer pipe (20), and the bottom of conveyer pipe (20) extends to the inside of device main part (1) and is linked together with annular pipe (11) to the internally mounted of conveyer pipe (20) has control valve (21).

6. The deproteinizing device for heparin sodium production according to claim 3, is characterized in that: the device main part (1) top of inlet pipe (9) one side is fixed with fixed plate (10), and the top of fixed plate (10) is provided with U type groove (23), U type groove (23) and retainer plate (13) block each other.