CN213302233U

CN213302233U - Analysis meter

Info

Publication number: CN213302233U
Application number: CN202021200391.9U
Authority: CN
Inventors: 方炜; 唐林勇; 商涛; 王中平
Original assignee: Leadway HK Ltd
Current assignee: Leadway HK Ltd
Priority date: 2020-01-16
Filing date: 2020-06-25
Publication date: 2021-05-28
Anticipated expiration: 2030-06-25
Also published as: CN113138285A; CN213875703U; CN213482251U; CN113138286A; CN213482252U; CN213482254U; CN213482253U; CN113203871A

Abstract

The utility model provides an analyzer, which comprises a motion mechanism, an optical detection mechanism and a biological sample detection reagent conveying platform driven by the motion mechanism, wherein the biological sample detection reagent conveying platform comprises a movable bearing plate and an object stage, and the object stage is placed on the bearing plate and can be separated from the bearing plate; the bearing plate is provided with a bearing plate, the bearing plate is provided with a magnet, the bearing plate is provided with a concave area, the bearing plate is provided with a magnet, the magnet is arranged on the bearing plate, and the bearing plate is provided with a magnet. The suction force of the magnetic block enables the objective table to be automatically positioned relative to the bearing plate, so that the technical effect of blind placement is achieved. The utility model can be used for detecting and analyzing specific protein, cholesterol, heme, urine routine, dry biochemistry and the like. The utility model has the advantages of easy and simple to handle, labour saving and time saving, work efficiency height.

Description

Analysis meter

Technical Field

The utility model belongs to the medical science field of detection especially relates to an analyzer for detect the biochemical data in the biological sample.

Background

Urine analyzers are instruments for measuring chemical components in urine and have important roles in the field of medical diagnosis. General urine analyzers all need to put test strips or test cards (the utility model discloses it is called "biological sample detection reagent" or simply "detection reagent") that have soaked in the urine on the microscope carrier, transport to the detection position and detect. When two kinds of test devices, i.e. a test strip and a test card, can be used in the same instrument, there are generally three kinds of implementation schemes.

The first solution is to put the test strips or cards on their respective carriers, and then place the carriers on a common carrier. Like the solution disclosed in the urine analyzer of us.pat. No.7118713b2, when an operator replaces a test strip or a test card with a test card or a test strip, the operator needs to replace the carriage at the same time, and a dead angle for cleaning is formed due to the placement position of the carriage on the stage.

The second solution is to provide a test card placement location on the carrier, and perform dimension processing on the test strip carrier, so that the test strip carrier can also be placed in the test card placement location, such as the solution disclosed in the urine analyzer of us.pat. No. 6239445b1. This solution, while using a smaller test card carrier than the first solution, still requires repeated replacement of the carrier during use.

The third scheme is to make a carrier into a double-sided design, wherein the carrier usually needs a larger volume, one side is provided with a test strip placing position, and the other side is provided with a test card placing position. When replacing the test strip or the test card with the test card or the test strip, an operator needs to clean and dry the used surface of the carrier, and then connect the used surface with the instrument, and the unused surface is used for placing the test card or the test strip.

Similar product is that the microscope carrier tow sides is put the detection material, and this type can be inconvenient relatively in the operation, when changing a material and detect, need take off the objective carrier, must put into on the reverse side again after the cleanness, and the space that just occupies also can be great.

Therefore, the microscope carrier design in the prior art enables the urine analyzer to have the problems of large instrument volume, multiple operation steps, large cleaning difficulty, inconvenience in use and the like.

In addition, when the detection reagent is placed on the stage and then detected by the detection instrument, the detection reagent needs to be accurately positioned in the detection instrument, so that the detection region on the detection reagent (the region where the biological sample is added and the detection reagent is detected) is accurately aligned with the optical detection unit on the detection instrument, and the detection result is output after the detection region is processed by spectroscopic analysis or the like. If the detection reagent is not accurately positioned in the detection instrument, the active light source emitted by the optical detection component on the detection instrument cannot accurately irradiate the detection area on the detection reagent, so that the detection result is inaccurate or even wrong. Although some prior art can fix a position accurately, the location process is loaded down with trivial details, wastes time and energy, and work efficiency is low. Therefore, there is a need for a reagent delivery platform for biological sample testing that is accurate at a predetermined level and easy and fast to operate, or an analyzer including the same.

SUMMERY OF THE UTILITY MODEL

The utility model provides an analyzer, which comprises a motion mechanism, an optical detection mechanism and a biological sample detection reagent conveying platform driven by the motion mechanism, wherein the biological sample detection reagent conveying platform comprises a movable bearing plate and an object stage, and the object stage is placed on the bearing plate and can be separated from the bearing plate; the bearing plate is provided with a bearing plate, the bearing plate is provided with a magnet, the bearing plate is provided with a concave area, the bearing plate is provided with a magnet, the magnet is arranged on the bearing plate, and the bearing plate is provided with a magnet.

Furthermore, the analyzer comprises two pairs of magnetic blocks which are spaced at a proper distance from each other, the two magnetic blocks on the object stage are opposite in polarity in the same direction, the two magnetic blocks on the bearing plate are opposite in polarity in the same direction, and the magnetic blocks on the object stage and the corresponding magnetic blocks on the bearing plate are arranged in an opposite attraction manner.

Furthermore, the contour of the depressed area on the bearing plate is rectangular, square, circular or elliptical, the area of the depressed area is larger than the area of the bottom surface of the magnetic block arranged on the objective table, the magnetic block on the objective table is cylindrical, and a movable space is arranged in the depressed area.

Furthermore, at least part of the magnetic block on the object stage protrudes out of the lower surface of the object stage and enters the depressed area on the bearing plate.

Furthermore, a liquid discharge channel is arranged on the upper surface of the bearing plate in the area close to the magnetic block on the bearing plate.

Furthermore, the upper surface of the bearing plate is provided with a liquid discharge hole communicated with the depressed area, and the liquid discharge hole penetrates through the lower surface of the bearing plate.

Further, a water-absorbing material is arranged in the liquid discharge hole, and the water-absorbing material is selected from the following materials: absorbent filter paper, sponge, nitrocellulose membrane and glass fiber membrane.

Has the advantages that:

the utility model discloses the analyzer is owing to adopt the magnetic path that is opposite sex attraction range, and the upper surface of loading board is equipped with the depressed area directly over its magnetic path, the size of depressed area is greater than the magnetic path that objective table salient in its lower surface, therefore, only need put the depressed area of loading board (need not accurate location) to the objective table that is equipped with detect reagent during the operation, under magnetic force's drive, the magnetic path on objective table and the loading board is close to as far as possible, the objective table just can reach the accurate position on the loading board automatically, realize automatic accurate location, thereby reach the technological effect of blindly putting. Therefore, the utility model has the advantages of easy and simple to handle, labour saving and time saving, work efficiency height. And simultaneously, the utility model discloses simple structure, low cost is fit for extensively promoting.

Drawings

Fig. 1 is a schematic structural view of an objective table for an analyzer according to the present invention.

Fig. 2 is a plan view of an objective table for an analyzer according to the present invention.

Fig. 3 is a schematic diagram of the present invention showing the detection board placed on the stage.

Fig. 4 is a sectional view a-a of fig. 3.

Fig. 5 is a schematic view of the back of the detection plate.

Fig. 6 is a schematic diagram of the test strip placed on the objective table for the analyzer of the present invention.

Fig. 7 is a sectional view a-a of fig. 6.

Fig. 8 is a schematic diagram of a detection unit of the analyzer.

Fig. 9 is a schematic view of the detection plate placed on the detection unit of the analyzer.

FIG. 10 is a schematic diagram of a test strip placed on a detection unit of an analyzer.

Figure 11 is an exploded view of the stage and carrier plate in combination.

Fig. 12 is a schematic view of a detection unit of an analyzer including another stage.

Fig. 13 is a schematic view of a detection plate configured with the stage of fig. 12.

Fig. 14 is a schematic view of a detection unit of an analyzer including another stage.

Fig. 15 is a schematic perspective view of a loading board according to a first embodiment of the present invention, showing an upper surface structure of the loading board.

FIG. 16 is similar to FIG. 15 but shows the magnetic blocks in a precisely positioned position.

FIG. 17 is a top view of the carrier plate and the stage after they are combined.

Fig. 18 is a cross-sectional view taken along line a-a of fig. 17.

Fig. 18A is an enlarged partial schematic view of fig. 18 at position a.

Fig. 18B is an enlarged partial schematic view of fig. 18 at position B.

Fig. 19 is a perspective view of the stage according to the second embodiment of the present invention, showing the lower surface structure of the stage.

Fig. 19A is an enlarged partial schematic view of fig. 19 at position a.

Fig. 19B is an enlarged partial schematic view of fig. 19 at position B.

Fig. 20 is a schematic perspective view of a bearing plate according to a second embodiment of the present invention, showing the upper surface structure (including the magnetic blocks) of the bearing plate.

Fig. 20A is an enlarged partial schematic view of fig. 20 at position a.

Fig. 20B is a partially enlarged schematic view of fig. 20 at position B.

Figure 21 is a side partial cross-sectional view of the carrier plate of figures 19 and 20 in combination with the stage to a precisely positioned position on the carrier plate.

Fig. 21A is an enlarged partial schematic view of fig. 21 at position a.

FIG. 22 is a schematic diagram of a first arrangement of the polarities of the magnetic blocks on the stage and the carrier plate.

FIG. 23 is a schematic diagram of a second arrangement of the polarities of the magnetic blocks on the stage and the carrier plate.

Fig. 24 is a schematic perspective view of a supporting board according to a third embodiment of the present invention, showing an upper surface structure (without magnetic blocks) of the supporting board.

Fig. 24A is an enlarged partial cross-sectional view taken along line a-a of fig. 24.

Fig. 25 is a schematic perspective view of a bearing plate according to a fourth embodiment of the present invention, showing an upper surface structure (without magnetic blocks) of the bearing plate.

Fig. 26 is a side sectional view of the object stage of the fourth embodiment of the present invention when the object stage is placed at the initial position of the loading board.

Fig. 26A is an enlarged partial schematic view of fig. 26 at position a.

FIG. 27 is similar to FIG. 26 but shows a precisely located position on the carrier plate.

Fig. 27A is an enlarged partial schematic view of fig. 27 at position a.

Fig. 28 is a schematic perspective view of a loading plate according to a fifth embodiment of the present invention, showing the upper surface structure (without magnetic blocks) of the loading plate.

Fig. 28A is an enlarged partial schematic view of fig. 28 at position a.

Fig. 28B is an enlarged partial schematic view of fig. 28 at position B.

FIG. 29 is similar to FIG. 28 but contains a magnetic block.

Fig. 30 is a top plan view of fig. 29.

Fig. 31 is a schematic perspective view of a bearing plate according to a sixth embodiment of the present invention, showing an upper surface structure (without magnetic blocks) of the bearing plate.

Fig. 32 is a perspective view of an object stage according to a sixth embodiment of the present invention, showing a lower surface structure (including magnetic blocks) of the object stage.

Fig. 33 is a top view (partially in section) of the initial position of fig. 31 and 32 in combination.

Figure 34 is similar to figure 33 but shows the stage reaching a precisely positioned position on the carrier plate.

Fig. 35 is a side sectional view of fig. 34.

Fig. 36 is a schematic perspective view of a bearing plate according to a seventh embodiment of the present invention, showing the upper surface structure (without magnetic blocks) of the bearing plate.

Fig. 37 is a perspective view of the stage according to the seventh embodiment of the present invention, showing the lower surface structure (without magnetic blocks) of the stage.

Fig. 38 is a top view of fig. 37 in combination with fig. 38.

Figure 39 is a cross-sectional view taken along line a-a of figure 38 showing the initial position of the stage in combination with the carrier plate.

Figure 40 is similar to figure 39 but shows the precise positioning of the stage in combination with the carrier plate.

Reference numerals

Object stage

100, 100 ', 100 ", magnetic block 101, 101 ', 401 ', groove 110, boss 111, object stage concave hole 111 ', convex strip 112, first slot 120, opening 121, convex block 122, second slot 130, slot convex pin 134 ', opening 131, convex block 132, protrusion 133, object stage lower surface 151, object stage upper surface 152, detection plate 200, 200 ', bottom plate 210, cover plate 220, concave hole 211, detection plate protrusion 211 ', depression 230, test strip 300, 300 ', substrate 301, detection test strip 302, test strip hole 301 ', detection unit 10, bearing plate 400, bearing plate upper surface 410, bearing plate lower surface 411,

depression area

412, 413,

vertical wall

416, 153, counter bore 414, 414 ', slope channel 415, protrusion 154, groove 417, cone chamfer guiding hole 418, drainage channel 419, 419 ', drainage port 420, first

magnetic hole

102, 402, second magnetic hole 102 ', 402 ', the gantry type PCB detection device comprises a gantry type bracket 500, a motor 600, a gear 700, a hexagonal head 900 and a detection photoelectric PCB 800.

Detailed Description

In the following detailed description, reference is made to the accompanying drawings, which form a part hereof, and in which is shown by way of illustration specific embodiments in which the invention may be practiced. We do not exclude that the invention can also be implemented with other embodiments and that the structure of the invention can be changed without violating the scope of the invention.

As shown in fig. 1-14, the objective table for the analyzer of the present invention can place both the detection plate and the test strip (the test strip is called test strip for short, for convenience, the detection plate and the test strip are called detection element together). The operator selects the detection plate or the test strip respectively according to the needs of the test items, and places the detection plate or the test strip on the objective table, completes information detection and analysis on the detection plate and the test strip, avoids frequently taking out or overturning the objective table from the analyzer, thereby effectively avoiding operation errors caused by complex operation of operators when the detection efficiency can be improved. Therefore, the detection plate limiting structure is arranged on the same surface, such as the front surface, of the object stage for bearing the test strip. This pick-up plate limit structure makes the pick-up plate by injecing in the suitable position of objective table to make the objective table get into the analysis appearance after, the testing result on the pick-up plate just in time is located the light source detection zone.

In some embodiments, the detection plate limiting structure is a boss matched with the detection plate, or a concave hole matched with the detection plate, or a groove for accommodating the detection plate, or a combination of the boss and the groove, or a combination of the concave hole and the groove.

In the embodiment shown in fig. 1 to 10, the stage 100 is provided with a boss 111. This boss 111 is as pick-up plate limit structure, and when placing pick-up plate 200 on the objective table, the boss is used for spacing pick-up plate 200 as limit structure and pick-up plate cooperation, plays the detection position of locating the pick-up plate at the objective table. Meanwhile, when the test strip is positioned on the objective table, the boss 111 also limits the position of the test strip on the objective table, so that the detection results of the detection plate and the test strip are just positioned in a proper light source detection area of the analyzer, and the detection results of the detection plate and the test strip can be accurately read by the analyzer. The raised platform also serves as a support structure for cooperating with the test strip to support the test strip 300 such that the test strip on the stage is in a substantially uniform plane.

In a further optimized design scheme, the height of the boss on the objective table is designed to ensure that the detection height of the test strip on the boss is the same as the detection height of the test strip in the detection plate on the boss. Therefore, no matter the detection plate or the test strip is positioned on the lug boss for detection, the detection plate or the test strip can be positioned in a proper light source detection area of the analyzer, and the detection results of the detection plate and the test strip are guaranteed to be accurately read.

The sensing plate 200, in the embodiment shown in fig. 5, includes a base plate 210 and a cover plate 220. The test strip for detection is attached to the base plate 210, and the cover plate 220 covers the base plate 210 and the test strip, thereby forming the detection plate 200. The bottom plate 210 of the detection plate is provided with a concave hole 211 corresponding to the boss 111 on the back surface, and the concave hole is a limiting structure on the detection plate. In an optimized design, the concave holes 211 on the detection plate are equal in size and position and correspond to the bosses 11 on the object stage. After the detection plate 200 is positioned on the stage 100, the concave hole 211 is engaged with the boss 111 on the stage.

The number of the bosses 111 is not limited, as long as the bosses can be matched with the concave holes of the detection plate, so that the detection plate can be placed at the correct detection position of the objective table. The number of the bosses 111 may be one or more. Specifically, the number of the bosses 111 is 1 to 5; in one specific embodiment, there are 3 bosses 111. The number of detection plate recesses 211 may be the same as or different from the number of bosses 111 on the stage. The number of the concave holes 211 is the same as that of the bosses 111, for example, when the number of the bosses 111 is three, the number of the concave holes 211 is also three. The number of the concave holes 211 is different from the number of the convex blocks 111, for example, when the number of the convex blocks 111 is three, the number of the concave holes 211 is four, wherein three concave holes correspond to the convex blocks, and the rest one concave hole can be used for other purposes or is idle when being matched with the objective table.

The bosses on the object stage can be uniformly distributed and arranged. In another preferred embodiment, the uneven arrangement of the bosses 111 is used to identify and define the orientation of the inspection board 200 on the stage 100, so as to ensure that the orientation of the inspection board 200 on the stage 100 is not wrong. The inaccurate or undetectable detection result caused by the reverse direction of the detection board 200 or the deviation of the detection board from the light source detection area of the analyzer is avoided. In the case where the bosses 111 are not uniformly arranged on the stage 100, specific ways include, but are not limited to: the bosses 111 are not arranged on the same straight line; alternatively, the pitches between the bosses 111 are different. For example, when there are two bosses 111, the central connecting line of the two bosses is not parallel to the horizontal central axis or the vertical central axis of the detection plate; for another example, when the number of the convex strips 111 is three or more, the distance between two adjacent convex strips 111 is different; or three or more bosses 111 are not provided in a straight line.

The arrangement of the concave holes 211 on the back surface of the detection plate base plate 210 is the same as the arrangement of the bosses 111 on the object stage 100. For example, when the bosses 111 are arranged in a straight line and have different pitches, the concave holes 211 are arranged in a straight line and have different pitches, and the pitches of the concave holes 211 are the same as the pitches of the bosses 111 in a one-to-one correspondence. When the projection 111 is located on the center line of the stage 100, the recess hole 211 is arranged on the center line of the base plate 210.

The recesses 211 may or may not penetrate the entire base plate 210 on the back of the base plate 210. When the boss on the objective table is assembled with the concave hole on the detection plate in a matching manner, the boss cannot influence the detection of the test paper strip in the detection plate.

In the embodiment shown in fig. 1-10, the area of the stage 100 in which the detector plate is stored is provided with a recess 110, the recess 110 of the stage being adapted to receive and retain the detector plate, and in some embodiments, a boss 111 is provided within the recess 110. The lug boss and the groove are combined to limit the detection plate. In addition, since the groove forms a large urine containing space, urine overflowing from the test strip 300 or the detection plate 200 can be contained. On the one hand, collect the urine in the recess and can not flow out the objective table and cause the pollution to the environment, on the other hand, because the recess bottom has certain distance with test paper strip or pick-up plate put on the boss, collect and can't contact test paper strip or pick-up plate in the urine that overflows of recess bottom to avoid different urine samples to pollute test paper strip or pick-up plate that are detecting. In a further optimized design, two side walls of the groove 110 are provided with raised strips 112 protruding from the side walls; the ribs 112 are positioned adjacent the ends of the grooves 110; the distance between the ribs 112 of the two side walls is equal to the width of the detection plate 200. The convex strips 112 on the two side walls are contacted and clamped with the side walls of the detection plate 200, so that the detection plate 200 is better fixed in the groove 110. One or more ribs 112 are provided on both sidewalls near both ends of the groove 110. The protrusions 112 respectively arranged on the two sidewalls of the groove 110 are symmetrical.

To facilitate access of the detector plate 200 to the stage 100, particularly from the recess, a depression 230, such as a symmetrically designed depression 230, is provided in the detector plate intermediate the two side walls of the base plate 210 and cover plate 220. When the detection plate is taken out from the groove, the space formed by the concave part can facilitate the fingers of an operator or the gripping clips of the mechanical arm to extend into the concave part to grip the detection plate.

In the embodiment shown in fig. 12-13, the position limiting structure of the detection plate on the stage is a concave hole 111', and the arrangement mode refer to the arrangement and the arrangement of the boss 111. Correspondingly, be equipped with on the back of pick-up plate 200 ' bottom plate with objective table shrinkage pool 111 ' complex pick-up plate arch 211 ', this pick-up plate arch 211 ' quantity and mode of arrangement all with objective table shrinkage pool 111 ' one-to-one, when pick-up plate 200 ' was located objective table 100 ', pick-up plate arch 211 ' one-to-one on the pick-up plate 200 ' inserted in the objective table shrinkage pool 111 ' on the objective table 100 ', made pick-up plate 200 ' by injecing on objective table 100 '.

The cross section of the boss or the concave hole of the limiting structure can be different in shape. For example, when there are 3 bosses, two of the bosses may be square and the third boss may be circular. Correspondingly, the concave holes on the detection plate matched with the detection plate are also respectively square and round.

The test strip 300 of the embodiment shown in fig. 8 includes a substrate 301 to which a test strip 302 is attached. The test paper may be urine joint test paper, lateral flow test paper, or the like.

The object stage is provided with a test strip positioning structure. For example, the positioning structure for positioning the test strip on the object stage is a slot or a convex pin. When the positioning structure is a convex nail, the convex nail is matched with the positioning structure, and the test strip is provided with a test strip hole. The test strip is clamped and positioned by the slot, or the test strip hole is matched with the convex pin on the objective table to position the test strip.

In the embodiment shown in fig. 1-10, the test strip positioning structure on the object stage 100 is a slot, and there are two slots, i.e. a first slot 120 and a second slot 130, corresponding to two ends of the test strip. The first slot 120 and the second slot 130 are respectively disposed at two ends of the groove 110, and position and support the test strip 300. In some embodiments, the first slot 120 is located at an end of the object stage 100 to facilitate insertion of the test strip 300 into the object stage 100 from the end of the object stage 100. When a liquid sample is added to the entire elongated test strip 300, the weight of the liquid will cause the middle of the test strip to sag, and when the sag prone middle is supported by the raised platform, it is ensured that the entire test strip is in nearly the same plane at the test site. Therefore, to ensure better support for the test strip 300, the center of the boss 111 is aligned with the center of the first slot 120 and the center of the second slot 130. That is, when the test strip 300 is located on the object stage 100, the two ends of the test strip 300 are respectively located in the first slot 120 and the second slot 130, and the boss 111 is located right below the test strip 300. The detection board 200 is placed in the area of the groove 110, the two ends of the test strip are placed in the clamping

grooves

120 and 130, and the thickness of the detection board 200 is larger than that of the test strip 300, so that in an optimal design, the depth of the groove 110 is larger than that of the first clamping groove 120 and the second clamping groove 130, and therefore after the test strip and the detection board are placed on the objective table, the detection result areas on the test strip and the detection board can be located at the same height and in a proper light source area. In a more specific embodiment, in order to ensure that the test strips are located at the same horizontal height, the height of the boss 111 in the groove 110 is the same as the height of the first slot 120 and the second slot 130 higher than the groove 110; or, the depth of the groove 110 is the same as that of the clamping

grooves

120 and 130, so that the test strip 300 is conveniently manufactured and integrally formed, meanwhile, the first clamping groove 120 and the second clamping groove 130 are both provided with the protruding blocks 122 and 132, and the heights of the protruding blocks 122 and 132 are the same as that of the bosses 111 in the groove, so that the test strip 300 in the clamping grooves and the groove is ensured to be in a horizontal state. The widths of the first clamping groove 120 and the second clamping groove 130 are the same as the width of the test strip 300, so that the clamping grooves can better clamp and position the test strip. Alternatively, two ends of the first card slot 120 are provided with openings 121; the width of the opening 121 is the same as the width of the test strip 300. That is, the side wall of the test strip 300 is engaged with the opening 121 of the first card slot, so that the first card slot 120 is fixed to one end of the test strip 300. Meanwhile, one end of the second card slot 130 is opened 131; symmetrical protrusions 133 are arranged at the opening 131. And, two side walls of the end of the second slot 130 are provided with symmetrical protrusions 133. The distance between the protrusions 133 and the sidewall protrusions 133 at the second slot opening 131 is the same as the width of the test strip 300. The other end of the test strip is fixed in the second slot 130 by the contact of the protrusion 133 at the opening and the protrusion 133 on the side wall with the side wall of the test strip 300.

In the embodiment of fig. 12-13, the strip alignment structure on the same surface of the object holder 100 'as the cavity is a male pin 314', and the male pin 314 'is aligned with the object holder cavity 111'. Meanwhile, a test strip hole 301 'is formed in the test strip 300'. When the test strip 300 ' is positioned on the object stage 100 ', the test strip hole 301 ' is sleeved on the convex pin 314 ', so that the test strip 300 ' is positioned. Of course, the test strip positioning structure may also further include a first slot 120 and a second slot 130, the protruding pins 314 ' are located in the first slot 120 and the second slot 130, and the test strip 300 ' is positioned by the first slot 120 and the second slot 130 cooperating with the protruding pins 314 '. Of course, the test strip positioning structure may also be the combination of the

slots

120, 130 and the protruding pins 314 ', so that the test strip 300' is fixed more firmly.

In the embodiment of fig. 14, the position-limiting structure on the stage 100 ″ is a boss 111, which corresponds to the position-limiting structure recess 211 of the detecting plate 200. The test strip positioning structure on the object stage 100 "is the convex pin 314 ', and the corresponding positioning structure of the test strip 300 ' is the test strip hole 301 '.

The detection plate and the test strip can be called a detection device, and the detection plate limiting structure and the test strip positioning structure can be called a detection device fixing structure.

An analyzer for biological sample analysis. The analyzer includes a stage and a detection unit. The object stage 100 is used in an analyzer, and specifically, the object stage 100 is configured to be placed in a detection unit 10 of the analyzer, bring the detection plate 200 or the test strip 300 into the detection unit 10, and read and analyze information of the detection plate 200 or the test strip 300 by the detection unit 10, so as to implement a detection and analysis function of the analyzer, as shown in fig. 8 to 14.

Specifically, as shown in fig. 1 to 14, the inspection unit 10 includes a stage, a stage conveyance stage, a movement mechanism, and an optical inspection mechanism. More specifically, the inspection unit 10 includes an

object stage

100 or 100' or 100 ″, a carrying platform including a carrying plate 400, a motion mechanism including a motor 600 and a gear 700, and an optical inspection mechanism including a light source (e.g., a hexagon head 900) and an inspection photo PCB 800. The hexagonal head is an optical path detection channel, 6 LED lamps are distributed in a circle around the hexagonal head, a PD receiving channel is arranged in the middle of the hexagonal head, and the hexagonal head is assembled with a detection photoelectric PCB and then installed on the gantry support. The motor 600 is connected with the gear 700, the gear 700 is meshed with the bearing plate 400, meanwhile, the gear 700, the hexagonal head 900 and the detection photoelectric PCB 800 are connected to the gantry bracket 500, the motor 600 drives the gear 700 to rotate, the gear 700 drives the bearing plate 400 to linearly reciprocate on the gantry bracket 500 through meshing, and finally, the object stage 100 on the bearing plate 400 is driven to linearly enter and exit in the gantry bracket 500; therefore, the object stage 100 enters the gantry support 500, and the information on the detection plate 200 or the test strip 300 on the object stage 100 is read by the cooperation of the hexagonal head 900 and the detection photoelectric PCB 800; and, the object stage 100 is separated from the gantry 500, the detection plate 200 or the test strip 300 on the object stage 100 can be replaced, and the object stage 100 can be taken down for cleaning.

The object stage 100 is placed on the loading board 400, and as shown in the examples of fig. 8 to 11, the object stage 100 is detachably fixed on the loading board 400. In one embodiment, as shown in fig. 11, the supporting board 400 is detachably assembled with the object stage 100 by the magnetic attraction of the magnet. Specifically, two ends of the back of the object stage are provided with magnetic holes, namely a first magnetic hole 102 and a second magnetic hole 102'; magnetic holes, namely a first magnetic hole 401 and a second magnetic hole 402', are arranged at two ends of the bearing plate. The magnetic block 101 is inserted into the first magnetic hole 102, and the magnetic block 101 'is inserted into the second magnetic hole 102', and similarly, a magnetic block (not shown) is also inserted into the magnetic hole 402. In addition, the two magnetic blocks 101 and 101 'in the first magnetic hole 102 and the second magnetic hole 102' on the object stage have opposite magnetism facing the carrier plate, for example, the side of the magnetic block 101 in the first magnetic hole 102 facing the carrier plate is an S pole, and the side of the magnetic block 101 'in the second magnetic hole 102' facing the carrier plate is an N pole. And the magnetism of a magnetic block is pressed into the magnetic holes 402 of the bearing plate 400 and attracted with the magnetic surfaces of the magnetic blocks on the back surface of the objective table, namely, the magnetic block is pressed into the first magnetic hole 401 of the bearing plate corresponding to the first magnetic hole 102 of the objective table, one surface of the magnetic block facing the objective table is an N pole, the magnetic block is pressed into the second magnetic hole 402 'of the bearing plate corresponding to the second magnetic hole 102' of the objective table, and the magnetic block on one surface of the magnetic block facing the objective table is an S pole. According to the principle that like poles repel and opposite poles attract, the object stage can only be placed 102 to 402 on the bearing plate, and 102 'to 402' is placed, so that the magnetic blocks in the magnetic holes are mutually attracted. If 102 is mistakenly assigned to 402 ', 102' is mistakenly assigned to 402, the magnetic blocks in the magnetic holes repel each other, and the stage cannot be placed on the carrier plate. This ensures that the object stage cannot be incorrectly placed in the direction of the carrier plate.

The following description of the operation of the detection unit 10 of the embodiment of fig. 8-10 of the present invention.

The detection plate 200 of the present embodiment is exemplified by an HCG detection plate, and a test strip for detecting HCG is placed in the detection plate. The test strip 300 in this embodiment is a urine joint test strip for routine urine tests, such as a urine 11 joint test strip, a urine 12 joint test strip, and the like.

When an operator needs to detect the HCG in the urine sample, the objective table 100 is driven by the carrier plate 400 to move out of the gantry 500 under the control of the motor 600, the detection plate 200 is arranged in the groove 110 of the objective table, so that the concave hole 211 of the detection plate 200 and the boss 111 in the groove are correspondingly clamped one by one, and the urine sample is added into the sample adding hole of the detection plate. Then, after the loading board 400 is driven to drive the stage 100 to move under the gantry bracket 500, the hexagonal head 900 and the inspection photoelectric PCB 800 read and analyze the inspection information on the inspection board 200. After the detection is finished, the motor 600 drives the bearing plate 400 to drive the object stage 100 to move away from the gantry bracket 500, and the detection plate 200 is taken down. If the urine test paper is used for urine routine test, the object stage 100 is driven by the carrier plate 400 to move out of the gantry 500, and the test strip 300 is placed in the first slot 120 and the second slot 130 of the object stage, so that the test strip 300 is clamped in the first slot 120 and the second slot 130, and the middle of the test strip 300 is supported on the boss 111. Then, after the loading board 400 is driven to drive the object stage 100 to move under the gantry 500, the hexagonal head 900 and the test photoelectric PCB 800 read and analyze the test information on the test strip 300. After the detection is finished, the motor 600 drives the carrying plate 400 to drive the object stage 100 to move away from the gantry 500, and the test strip 300 is taken down. The test paper strip that the objective table both can put the urine antithetical couplet tests, also can put the HCG board and test. During the conversion process of the urine-associated test paper and the detection plate, the object stage does not need to be moved.

When all the detections are completed, the motor 600 drives the object stage 100 to move to the lower part of the gantry 500 for storage. When the object stage 100 needs to be cleaned, the bearing plate 400 and the object stage 100 move out of the gantry support 500 through the motor 600, the object stage 100 is taken down from the bearing plate 400 to be cleaned, and after cleaning is completed, the magnetic blocks 101 of the object stage and the magnetic blocks 401 of the bearing plate are correspondingly and fixedly connected together through magnetic attraction. The loading plate 400 and the loading platform 100 are moved into the gantry 500 by the motor 600.

Referring to fig. 1-40, the present invention further provides an analyzer, which comprises a moving mechanism, an optical detection mechanism, and a biological sample detection reagent delivery platform driven by the moving mechanism. The motion mechanism includes a motor 600, a gear 700, and the like. The biological sample detection reagent delivery platform includes a movable carrier plate 400 and a stage 100. The object stage 100 is placed on the loading plate 400 and can be separated from the loading plate 400. The side of the carrier 400 facing the stage 100 is an upper surface 410, and the opposite side is a lower surface 411. The side of the stage 100 facing the carrier 400 is a lower surface 151, and the opposite side is an upper surface 152 (fig. 19). The object stage 100 and the carrier plate 400 are respectively provided with magnetic blocks 101 and 101' which are magnetically attracted. The upper surface 410 of the carrier plate is provided with recessed

areas

412 and 413 in the areas directly above the magnetic blocks, when the object stage 100 is placed on the carrier plate 400, the magnetic blocks 101 and 101 'on the object stage are located in the recessed

areas

412 and 413, and the attraction force of the magnetic blocks 101 and 101' automatically moves the object stage 100 to a designated position on the carrier plate 400, so that the object stage 100 is automatically positioned relative to the carrier plate 400.

Please refer to fig. 15-18B, which illustrate a first embodiment of the present invention. The upper surface 410 of the carrier plate 400 is provided with recessed areas 412, 413 (shown in fig. 18A, 18B) in the areas close to the magnetic blocks 401, 401 'on the carrier plate, preferably at positions directly above where the two magnetic blocks 401, 401' are placed on the carrier plate, respectively. The contour of the recessed

regions

412, 413 is rectangular, square, circular or oval (only rectangular is shown in fig. 15 and 16, and other shapes are omitted), and the area of the recessed regions is larger than the outer contour of the magnetic block 101 in the object stage 100. Therefore, when the object stage 100 is placed on the carrier board 400, only the magnetic blocks 101 and 101 'in the object stage 100 need to be placed in the recessed

areas

412 and 413 of the upper surface 410 of the carrier board 400 (i.e. the pre-set areas), and the magnetic blocks 101 and 101' in the object stage 100 still have movable spaces in the recessed

areas

412 and 413 of the upper surface 410 of the carrier board 400, and do not need to be placed at the precise positioning positions. Since the outline of the recessed

areas

412, 413 is rectangular, square, circular or elliptical, and the area is larger than the outline of the magnetic blocks 101, 101 'in the object stage 100, the magnetic blocks 101, 101' on the object stage can be easily placed in the recessed

areas

412, 413 respectively, so that the operation is very convenient.

In order to position more accurately, the analyzer of the present invention comprises two pairs of magnetic blocks 101 and 101' (arranged along the longitudinal direction of the objective table 100 and the loading plate 400, wherein, for the sake of simplicity, only one pair of magnetic block structure and positioning mode will be described in detail below, and the other pair of magnetic blocks can be analogized). The two magnetic blocks 101 and 101' on the object stage 100 have opposite polarities in the same direction (for example, a vertical downward direction); the polarities of the two magnetic blocks 401 and 401' on the carrier plate 400 in the same direction (e.g., a vertical downward direction) are also opposite; therefore, the magnetic blocks on the object stage 100 and the corresponding magnetic blocks on the carrier plate 400 are arranged in opposite attraction (the arrangement is as follows).

Fig. 22 and 23 show two arrangements of the magnetic properties of the magnetic blocks on the object stage and carrier plate (this arrangement is applicable to all embodiments).

Please refer to fig. 19-21A, which illustrate a second embodiment of the present invention. The present embodiment differs from the first embodiment in that: the upper surface 410 of the carrier plate 400 and the lower surface 151 of the object stage 100 are respectively provided with a positioning structure which are matched with each other. In this embodiment, the alignment structure includes

vertical walls

416, 153 disposed on the upper surface 410 of the carrier plate and the lower surface 151 of the stage, respectively. When the stage 100 is placed in a predetermined area of the carrier plate, the

vertical walls

416 and 153 are abutted against each other by the attraction of the magnet 101, thereby achieving automatic positioning. Referring to fig. 21A, the axes of the magnetic blocks on the carrier plate 400 and the object stage 100 are not coincident, but are offset by a distance F between 0.5 mm and 3.0 mm, so that the

magnetic blocks

101 and 401 attract each other to urge the

vertical walls

416 and 153 to continuously abut against each other. So designed, it can be ensured that the object stage 100 is more precisely positioned on the loading plate 400.

Please refer to fig. 24 and 24A, which illustrate a third embodiment of the present invention. The present embodiment differs from the first embodiment in that: the recessed

areas

412 and 413 on the upper surface 410 of the carrier plate are replaced by two counter bores and 414' with the outline size corresponding to the outline size of the magnetic block 101 protruding from the lower surface 151 of the stage (as shown in fig. 24). In other words, the upper surface 410 of the carrier plate is provided with counter bores 414, 414 ' directly above the two magnetic blocks 401, 401 ' thereof, which are adapted to the shapes of the two magnetic blocks 101, 101 ' fixed on the stage (fig. 24A only illustrates the positional relationship of one pair of magnetic blocks 101 ', 401 ', and the positional relationship of the other pair of

magnetic blocks

101, 401 can be referred to). That is, the magnetic block 101 '(shown in phantom in FIG. 24A) on the stage at least partially protrudes above the lower surface 151 of the stage and can at least partially enter the counterbore 414', but the magnetic block 101 'on the stage is constrained from wobbling in the counterbore 414' in a direction parallel to the upper surface 410 of the stage as much as possible. The magnetic block 101 'on the object stage is a cylinder, the contour of the counter bore 414' on the bearing plate is also a cylinder, and the diameter of the counter bore 414 'is 0.1-1.0 mm larger than that of the magnetic block 101'. In order to guide the magnetic block 101 ' to enter the counter bore 414 ' more easily in a direction perpendicular to the upper surface 410 of the loading plate, in an aspect of the present embodiment, a conical chamfered guide hole 418 with a larger size is provided at the uppermost opening of the counter bore 414 '. In a preferred embodiment, the depth L of the chamfer is 0.3-2.0 mm, and the included angle a between the chamfer and the vertical axis of the counterbore is 30-60 degrees (preferably 40 degrees). It should be noted that in other aspects of this embodiment, the conical chamfered guide holes 418 may not be included at the uppermost openings of the counterbores 414, 414'.

Please refer to fig. 25-27A, which illustrate a fourth embodiment of the present invention. The present embodiment differs from the third embodiment in that: the upper surface 410 of the carrier plate is provided with a section of ramp channel 415 communicated with the counterbore 414, and the ramp channel 415 gradually descends from a position far away from the counterbore 414 to a position close to the counterbore 414 (the other side of the ramp channel 415' is similar in structure and is not described again). When the object table 100 is placed at a predetermined position on the carrier plate 400 (shown in fig. 26A), under the attraction of the magnetic blocks, the magnetic blocks on the object table 100 slide into the counter bores 414, 414 ' along the ramp channels 415, 415 ' substantially in the longitudinal direction of the carrier plate 400, respectively, and abut against the side walls of the counter bores 414, 414 ', thereby achieving precise positioning (shown in fig. 27A).

Referring to fig. 28-30, a fifth embodiment of the present invention is shown. This embodiment combines the structures of the first and third embodiments, i.e., a design that includes both a recessed region 412 and a counterbore 414, with the counterbore 414 being located within the recessed region 412. When the object table 100 is placed at a predetermined position on the loading board 400 (the magnetic block 101 is placed in the recessed area 412), the magnetic block on the object table 100 automatically slides into the counter bore 414 to abut against the side wall of the counter bore 414 under the attraction of the magnetic block, so as to achieve precise positioning (as shown in fig. 29 and 30).

Referring to fig. 28A and 28B, taking the fifth embodiment as an example, the upper surface 410 of the carrier plate is provided with drainage channels 419, 419 ' communicating with the counter bores 414, 414 ' respectively in the areas close to the magnetic blocks 401, 401 ' on the carrier plate, so as to drain the liquid (e.g. urine) leaked therein in time. Further, the drain 419 may further include drain holes 420. In one design, the drain holes 420 have a lower floor than the drain channels 419, but do not extend through to the lower surface 411 of the carrier plate. In another design, the drain holes 420 extend through to the lower surface 411 of the carrier plate. Alternatively, a water absorbent material may be placed at the bottom of the counter bores 414, 414' to absorb liquid that leaks there. Water-absorbing materials may also be placed in the drainage channels 419 and/or the drainage holes 420 to absorb liquid that leaks into them. These water-absorbing materials are selected from: absorbent filter paper, sponge, nitrocellulose membrane and glass fiber membrane.

Please refer to fig. 15, fig. 16, fig. 18A and fig. 20B. The design of the drain channel 419 and the drain hole 420 is applicable not only to the fifth embodiment but also to other embodiments. For example, in the first, second, sixth, and seventh embodiments, the upper surface 410 of the carrier plate is provided with drain holes 420 communicating with the recessed area, and the drain holes 420 may or may not penetrate through to the lower surface 411 of the carrier plate. In the third and fourth embodiments, the upper surface 410 of the carrier plate is provided with a drain channel 419 communicating with the counter bores 414, 414', and the drain channel 419 includes a drain hole 420, and the drain hole 420 may or may not penetrate through to the lower surface 411 of the carrier plate.

Please refer to fig. 31-35, which illustrate a sixth embodiment of the present invention. The present embodiment differs from the previous embodiments in that: the positioning structure is different. In this embodiment, the positioning structure comprises a protrusion 154 and a groove 417 which are respectively disposed on the upper surface 410 of the carrier plate and the lower surface 151 of the stage and are matched with each other, the protrusion 154 falls into the groove 417, and the suction force of the magnetic block makes the sidewalls of the protrusion 154 and the groove 417 abut against each other, thereby realizing automatic positioning. In this embodiment, the orthographic projection of the protrusions 154 and the recesses 417 on the carrier plate 400 and the object table 100 on the upper surface 410 of the carrier plate or the lower surface 151 of the object table has a wedge-shaped outer contour. When the stage 100 is placed at a predetermined position on the loading plate 400 (the protrusion 154 is placed in the groove 417), under the attraction of the magnetic blocks, the protrusion 154 slides in the groove 417 along the longitudinal direction (X direction in fig. 33) of the loading plate 400, and the sidewalls of the protrusion 154 and the groove 417 abut against each other, thereby achieving precise positioning (see fig. 34 and 35). Although the protrusion 154 is shown to be designed on the object stage 100 and the groove 417 is shown to be designed on the carrier plate 400, the protrusion 154 may be designed on the carrier plate 400 and the groove 417 may be designed on the object stage 100.

Please refer to fig. 36-40, which illustrate a seventh embodiment of the present invention. The present embodiment differs from the sixth embodiment in that: the cross-sectional profile of the protrusions 154 'and the recesses 417' of the carrier plate and the object stage is a wedge or an inverted trapezoid with a wide top and a narrow bottom. When the object table 100 is placed at a predetermined position on the loading plate 400, the protrusion 154 'slides into the groove 417' in a direction substantially perpendicular to the upper surface 410 of the loading plate under the attraction of the magnetic blocks, so as to guide the object table 100 to automatically reach a precise positioning position on the loading plate 400. Although the protrusion 154 'is shown to be designed on the object stage 100 and the groove 417' is shown to be designed on the carrier plate 400, the protrusion 154 'may be designed on the carrier plate 400 and the groove 417' may be designed on the object stage 100.

The above description is only a specific embodiment of the present invention, and does not therefore limit the scope of the invention as claimed. All the equivalent structures or equivalent flow changes made by using the contents of the specification and the drawings of the present invention, or the direct or indirect application in other related technical fields, should be included in the protection scope of the present invention.

Claims

1. An analyzer, characterized by: the biological sample detection reagent conveying platform comprises a movable bearing plate and an object stage, wherein the object stage is placed on the bearing plate and can be separated from the bearing plate; the bearing plate is provided with a bearing plate, the bearing plate is provided with a magnet, the bearing plate is provided with a concave area, the bearing plate is provided with a magnet, the magnet is arranged on the bearing plate, and the bearing plate is provided with a magnet.

2. The analyzer as set forth in claim 1, wherein: the magnetic carrier comprises two pairs of magnetic blocks which are spaced at a proper distance from each other, the two magnetic blocks on the object stage are opposite in polarity in the same direction, the two magnetic blocks on the bearing plate are opposite in polarity in the same direction, and the magnetic blocks on the object stage and the corresponding magnetic blocks on the bearing plate are arranged in an opposite attraction manner.

3. The analyzer as set forth in claim 2, wherein: the contour of the depressed area on the bearing plate is rectangular, circular or elliptical, the area of the depressed area is larger than the area of the bottom surface of the magnetic block arranged on the object carrying plate, the magnetic block on the object carrying table is cylindrical, and a movable space is arranged in the depressed area.

4. An analyser according to claim 1, 2 or 3 wherein: the magnet on the objective table at least partially protrudes out of the lower surface of the objective table and enters the depressed area on the bearing plate.

5. An analyser according to claim 1, 2 or 3 wherein: the upper surface of the bearing plate is provided with a liquid drainage channel in the area close to the magnetic block on the bearing plate.

6. An analyser according to claim 1, 2 or 3 wherein: the upper surface of the bearing plate is provided with a liquid discharge hole communicated with the depressed area, and the liquid discharge hole penetrates through the lower surface of the bearing plate.

7. The analyzer as set forth in claim 6, wherein: the liquid discharge hole is internally provided with water-absorbing materials which are water-absorbing filter paper, sponge, nitrocellulose membrane or glass fiber membrane.

8. The analyzer as claimed in claim 3, wherein the contour of the depression on the carrier plate is square.