CN213252596U - Transcranial magnetic pseudo-stimulation beat control circuit - Google Patents
Transcranial magnetic pseudo-stimulation beat control circuit Download PDFInfo
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- CN213252596U CN213252596U CN202021366152.0U CN202021366152U CN213252596U CN 213252596 U CN213252596 U CN 213252596U CN 202021366152 U CN202021366152 U CN 202021366152U CN 213252596 U CN213252596 U CN 213252596U
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Abstract
The utility model discloses a transcranial magnetic pseudo-stimulation beat control circuit, which comprises two sections of same stimulating coils, a direct current power supply and a control module, wherein the head end and the tail end of one section of stimulating coil are respectively provided with a contact A1 and a contact A3, and the head end and the tail end of the other section of stimulating coil are respectively provided with a contact A4 and a 5; the positive lead wire of the direct current power supply is provided with a contact B1 and a contact B5, and the positions of the contact B1 and the contact B5 correspond to the positions of the contact A1 and the contact A5 respectively; the negative electrode lead wire of the direct current power supply is provided with a contact C3, a contact C4 and a contact C5, and the positions of the contact C3, the contact C4 and the contact C5 respectively correspond to the positions of the contact A3, the contact A4 and the contact A5; the contact A1, the contact A3, the contact A4 and the contact A5 are respectively provided with a switch K1, a switch K3, a switch K4 and a switch K5.
Description
Technical Field
The utility model belongs to the technical field of transcranial magnetic stimulation, in particular to a transcranial magnetic pseudo-stimulation beat control circuit.
Background
Transcranial magnetic stimulation (TMS for short) is a magnetic stimulation technology which utilizes a pulsed magnetic field to act on the central nervous system to change the membrane potential of cortical nerve cells, so that induced current is generated to influence the metabolism in the brain and the neuroelectrical activity, thereby causing a series of physiological and biochemical reactions. TMS has the advantages of no wound, no pain, and high safety, and can be used for stimulating cranial nerve, nerve root and peripheral nerve. At present, the method is widely used in the fields of neuroscience and brain science research and in the diagnosis and treatment of clinical diseases.
When the efficacy of the transcranial magnetic stimulation system is judged, a control experiment needs to be carried out, and generally, one experiment is divided into an experiment group and a control group. An experimental group, which is a group of subjects to be subjected to experimental variable processing; the control group, also called control group, is the object group not receiving the experimental variable treatment, and as to which is the experimental group and which is the control group, it is generally determined randomly for the experimental hypothesis, so that theoretically, since the influence of the independent variables of the experimental group and the control group is equal and balanced, the difference between the experimental group and the control group can be considered as the effect from the experimental variable, and the experimental result is credible. The existing comparison experiment of the transcranial magnetic stimulation curative effect weakens the stimulation intensity of the coil to the experimental object by changing the relative position of the stimulation coil, for example, changing the posture of the 8-shaped coil by 90 degrees. However, such control experiments did not achieve double-blind effects.
The patent with publication number CN109621210A discloses an 8-shaped coil for transcranial magnetic stimulation contrast experiment, which contains a first circular coil and a second circular coil, wherein the first circular coil is wound counterclockwise, the input end is a2, the output end is a1, the second circular coil is wound clockwise, the input end is B1, and the output end is B2, the input end and the output end of the two circular coils are connected and combined through 4 single switches K1, K2, K3, and K4 to form different configuration states with the same or opposite current directions at the intersection point of the two circular coils, and the switch states of the single switch K1, the single switch K2, the single switch K3, and the single switch K4 are controlled by a control module. The invention also provides a configuration management method of the 8-shaped coil, which is used for configuring the 8-shaped coil by controlling the switching states of the single switches K1, K2, K3 and K4 so as to freely realize normal stimulation or pseudo stimulation. Double-blind effect can be realized for operators and experimenters in the control experiment. Although the patent can realize the random switching between normal stimulation and pseudo stimulation, the patent realizes double-blind effect on operators and experimenters; however, the pseudo stimulation of the control group is only the pseudo stimulation with the stimulation intensity of 0, and the pseudo stimulation with other stimulation intensities is not available, the configuration mode is single, and the configuration mode can only draw the conclusion whether the normal stimulation with the stimulation intensity of 100% can produce the treatment effect or not, and cannot draw the conclusion whether the normal stimulation with the stimulation intensity is reduced can also produce the treatment effect or not.
Disclosure of Invention
The utility model aims at providing a through cranium magnetism pseudo-stimulation bat control circuit has solved the single problem of pseudo-stimulation bat configuration mode among the prior art.
In order to achieve the above object, the utility model adopts the following technical scheme:
a transcranial magnetic pseudo-stimulation beat control circuit comprises two sections of same stimulation coils, a direct-current power supply and a control module, wherein the two sections of the same stimulation coils are coaxially arranged at intervals, the head end and the tail end of one section of the stimulation coils are respectively provided with a contact A1 and a contact A3, and the head end and the tail end of the other section of the stimulation coils are respectively provided with a contact A4 and a contact A5; the positive lead wire of the direct current power supply is provided with a contact B1 and a contact B5, and the positions of the contact B1 and the contact B5 correspond to the positions of the contact A1 and the contact A5 respectively; the negative electrode lead wire of the direct current power supply is provided with a contact C3, a contact C4 and a contact C5, and the positions of the contact C3, the contact C4 and the contact C5 respectively correspond to the positions of the contact A3, the contact A4 and the contact A5; the contact A1, the contact A3, the contact A4 and the contact A5 are respectively provided with a switch K1, a switch K3, a switch K4 and a switch K5; the switch K1, the switch K3, the switch K4 and the switch K5 are respectively connected with the control module.
Specifically, the switch K3 and the switch K5 are both single-pole double-throw switches, a fixed contact of the switch K3 is connected with a contact A3, and a movable contact of the switch K3 is switched among a contact a4, a contact C3 and a vacant position; the fixed contact of the switch K5 is connected with the contact A5, and the movable contact of the switch K5 is switched among the contact B5, the contact C5 and the vacant position.
Specifically, the pseudo-stimulation beat includes 3 configuration modes, which are respectively: normal stimulation at 100% stimulation intensity, pseudo stimulation at 50% stimulation intensity, and pseudo stimulation at 0 stimulation intensity.
The coil configuration mode of 100% stimulation intensity is as follows: the switch K1 is closed, and the contact A1 is electrically connected with the contact B1; the moving contact of the switch K3 is contacted with a contact A4, and a contact A3 is electrically connected with a contact A4; the moving contact of the switch K5 is contacted to C5, and the contact A5 is electrically connected with the contact C5;
the coil configuration at 50% stimulation intensity was: the switch K1 is closed, and the contact A1 is electrically connected with the contact B1; the moving contact of the switch K3 is contacted with a contact C3, and a contact C3 is electrically connected with a contact A3;
the coil configuration mode of 0 stimulation intensity is as follows: the switch K1 is closed, and the contact A1 is electrically connected with the contact B1; the moving contact of the switch K3 is contacted with a contact C3, and a contact C3 is electrically connected with a contact A3; the switch K4 is closed, and the contact A4 is electrically connected with the contact C4; the moving contact of the switch K5 is contacted to B5, and the contact A5 is electrically connected with the contact B5.
Preferably, a contact A2 is led out from the middle section of the stimulation coil where the contact A1 is located, a contact C2 is further arranged on the negative electrode lead-out wire of the direct current power supply, the position of the contact C2 corresponds to the position of the contact A2, and a switch K2 is arranged on the contact A2; the switch K2 is connected with the control module.
Optionally, the contacts a1 and a2 divide the length of the stimulation coil into 1/5 of the total length of the stimulation coil.
Specifically, the pseudo-stimulation beat includes 4 configuration modes, which are respectively: normal stimulation at 100% stimulation intensity, pseudo stimulation at 50% stimulation intensity, pseudo stimulation at 10% stimulation intensity, and pseudo stimulation at 0 stimulation intensity. In the treatment process, 4 configuration modes are used for random treatment, and finally, the treatment effect is compared with the random mode to achieve the double-blind effect.
Wherein, the coil configuration mode of 10% stimulation intensity is as follows: the switch K1 is closed, and the contact A1 is electrically connected with the contact B1; switch K2 is closed and contact C2 is electrically connected to contact a 2.
Compared with the prior art, the beneficial effects of the utility model are that: the utility model can realize the control experiment of true stimulation and false stimulation, and realize double blind effect for operators and experimenters; meanwhile, the reference group of the application is provided with a plurality of pseudo-stimulation configuration modes with different stimulation intensities, so that the influence of different stimulation intensities on the transcranial magnetic stimulation effect can be verified, and the application value is higher.
Drawings
FIG. 1 is a schematic diagram of a transcranial magnetic pseudo-stimulation beat control circuit of the present invention;
fig. 2 is a schematic diagram of a coil configuration with 100% stimulation intensity according to an embodiment of the present invention;
fig. 3 is a schematic diagram of a coil configuration with 50% stimulation intensity according to an embodiment of the present invention;
fig. 4 is a schematic diagram of a coil configuration with 0 stimulation intensity in an embodiment of the present invention;
fig. 5 is a schematic diagram of a coil configuration with 10% stimulation intensity in an embodiment of the present invention;
Detailed Description
The technical solution of the present invention will be described clearly and completely with reference to the accompanying drawings, and obviously, the described embodiments are only some embodiments, not all embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
As shown in fig. 1, this embodiment provides a transcranial magnetic pseudo-stimulation beat control circuit, which includes two sections of the same stimulation coil, a dc power supply and a control module, where the two sections of the same stimulation coil are coaxially disposed at intervals, a contact a1 and a contact A3 are respectively disposed at the head end and the tail end of one section of the stimulation coil, at least 1 contact a2 (different numbers of contacts may be set according to experimental requirements) is further disposed between the contact a1 and the contact A3, and a contact a4 and a contact a5 are respectively disposed at the head end and the tail end of the other section of the same stimulation coil; the positive lead wire of the direct current power supply is provided with a contact B1 and a contact B5, and the positions of the contact B1 and the contact B5 correspond to the positions of the contact A1 and the contact A5 respectively; the negative electrode lead wire of the direct current power supply is provided with a contact C2, a contact C3, a contact C4 and a contact C5, and the positions of the contact C2, the contact C3, the contact C4 and the contact C5 respectively correspond to the positions of a contact A2, a contact A3, a contact A4 and a contact A5; the contact A1, the contact A2, the contact A3, the contact A4 and the contact A5 are respectively provided with a switch K1, a switch K2, a switch K3, a switch K4 and a switch K5; the switch K1, the switch K2, the switch K3, the switch K4 and the switch K5 are respectively connected with the control module.
Specifically, the switch K3 and the switch K5 are both single-pole double-throw switches, a fixed contact of the switch K3 is connected with a contact A3, and a movable contact of the switch K3 is switched among a contact a4, a contact C3 and a vacant position; the fixed contact of the switch K5 is connected with the contact A5, and the movable contact of the switch K5 is switched among the contact B5, the contact C5 and the vacant position.
Optionally, the contact a1 and the contact a2 divide the length of the stimulation coil to account for 1/5 of the total length of one piece of the stimulation coil, that is, to account for 1/10 of the total length of two pieces of the stimulation coil. (in specific implementation, the leading-out position of the contact A2 can be set according to the experimental requirements)
Specifically, the pseudo-stimulation beat includes 4 configuration modes, which are respectively: normal stimulation at 100% stimulation intensity, pseudo stimulation at 50% stimulation intensity, pseudo stimulation at 10% stimulation intensity, and pseudo stimulation at 0 stimulation intensity. In the treatment process, 4 configuration modes are used for random treatment, and finally, the treatment effect is compared with the random mode to achieve the double-blind effect.
As shown in fig. 2, the coil configuration for 100% stimulation intensity is: the switch K1 is closed, and the contact A1 is electrically connected with the contact B1; the moving contact of the switch K3 is contacted with a contact A4, and a contact A3 is electrically connected with a contact A4; the moving contact of the switch K5 is contacted to C5, and the contact A5 is electrically connected with the contact C5; at the moment, the two sections of stimulating coils are all connected, the current directions on the two sections of stimulating coils are the same, and the pseudo-stimulating beat generates normal stimulation with 100% stimulation intensity according to the magnetic field superposition principle;
as shown in fig. 3, the coil configuration for 50% stimulation intensity is: the switch K1 is closed, and the contact A1 is electrically connected with the contact B1; the moving contact of the switch K3 is contacted with a contact C3, and a contact C3 is electrically connected with a contact A3; at the moment, only one section of stimulating coil is completely connected, and the pseudo-stimulation beat generates pseudo-stimulation with 50% of stimulation intensity;
as shown in fig. 4, the coil arrangement of 0 stimulation intensity is: the switch K1 is closed, and the contact A1 is electrically connected with the contact B1; the moving contact of the switch K3 is contacted with a contact C3, and a contact C3 is electrically connected with a contact A3; the switch K4 is closed, and the contact A4 is electrically connected with the contact C4; the moving contact of the switch K5 is contacted to B5, and the contact A5 is electrically connected with the contact B5; at the moment, the two sections of stimulating coils are all connected, the directions of currents on the two sections of stimulating coils are opposite, and the pseudo-stimulating beat generates pseudo-stimulation with the stimulation intensity of 0 according to the magnetic field superposition principle;
as shown in fig. 5, the coil configuration for 10% stimulation intensity is: the switch K1 is closed, and the contact A1 is electrically connected with the contact B1; the switch K2 is closed, and the contact C2 is electrically connected with the contact A2; at this time, only one section of the stimulation coil between the contact A1 and the contact A2 is connected, and the length of the section of the stimulation coil accounts for 10% of the total length of the two sections of the stimulation coils, so that the pseudo stimulation beat generates pseudo stimulation with 10% stimulation intensity.
In the embodiment, when a transcranial magnetic stimulation contrast test is performed, the 4 coil configuration modes are randomly selected by the control module, recovery time is reserved between the 4 configuration modes, and finally, the treatment effect is compared with the random mode to achieve the double-blind effect. In addition, the embodiment is provided with 4 configuration modes with different magnetic field strengths, so that the influence of different magnetic field strengths on the transcranial magnetic stimulation effect can be verified.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. A transcranial magnetic pseudo-stimulation beat control circuit is characterized by comprising two sections of same stimulation coils, a direct-current power supply and a control module, wherein the two sections of stimulation coils are coaxially arranged at intervals, the head end and the tail end of one section of stimulation coil are respectively provided with a contact A1 and a contact A3, and the head end and the tail end of the other section of stimulation coil are respectively provided with a contact A4 and a contact A5; the positive lead wire of the direct current power supply is provided with a contact B1 and a contact B5, and the positions of the contact B1 and the contact B5 correspond to the positions of the contact A1 and the contact A5 respectively; the negative electrode lead wire of the direct current power supply is provided with a contact C3, a contact C4 and a contact C5, and the positions of the contact C3, the contact C4 and the contact C5 respectively correspond to the positions of the contact A3, the contact A4 and the contact A5; the contact A1, the contact A3, the contact A4 and the contact A5 are respectively provided with a switch K1, a switch K3, a switch K4 and a switch K5; the switch K1, the switch K3, the switch K4 and the switch K5 are respectively connected with the control module.
2. The transcranial magnetic pseudo-stimulation beat control circuit according to claim 1, wherein the switch K3 and the switch K5 are both single-pole double-throw switches, a fixed contact of the switch K3 is connected with a contact A3, and a movable contact of the switch K3 is switched among a contact a4, a contact C3 and a vacant position; the fixed contact of the switch K5 is connected with the contact A5, and the movable contact of the switch K5 is switched among the contact B5, the contact C5 and the vacant position.
3. A transcranial magnetic pseudo-stimulation beat control circuit according to claim 1 or 2, wherein the pseudo-stimulation beat comprises 3 configuration modes, respectively: normal stimulation at 100% stimulation intensity, pseudo stimulation at 50% stimulation intensity, and pseudo stimulation at 0 stimulation intensity.
4. The transcranial magnetic pseudo-stimulation beat control circuit according to claim 1, wherein a contact A2 is led out from the middle section of the stimulation coil where the contact A1 is located, a negative electrode lead-out wire of the direct current power supply is further provided with a contact C2, the position of the contact C2 corresponds to the position of the contact A2, and a switch K2 is arranged on the contact A2; the switch K2 is connected with the control module.
5. The transcranial magnetic pseudo-stimulation beat control circuit according to claim 4, wherein the contact A1 and the contact A2 divide the length of the stimulation coil into 1/5 of the total length of the stimulation coil.
6. A transcranial magnetic pseudo-stimulation beat control circuit according to claim 5, wherein the pseudo-stimulation beat comprises 4 configuration modes, which are respectively: normal stimulation at 100% stimulation intensity, pseudo stimulation at 50% stimulation intensity, pseudo stimulation at 10% stimulation intensity, and pseudo stimulation at 0 stimulation intensity.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202021366152.0U CN213252596U (en) | 2020-07-13 | 2020-07-13 | Transcranial magnetic pseudo-stimulation beat control circuit |
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| CN202021366152.0U CN213252596U (en) | 2020-07-13 | 2020-07-13 | Transcranial magnetic pseudo-stimulation beat control circuit |
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| CN213252596U true CN213252596U (en) | 2021-05-25 |
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| CN202021366152.0U Active CN213252596U (en) | 2020-07-13 | 2020-07-13 | Transcranial magnetic pseudo-stimulation beat control circuit |
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