CN213172343U - Abamectin preparation production system for dogs - Google Patents

Abstract

The utility model relates to a bio-pharmaceuticals technical field, concretely relates to is an avermectin preparation production system for dog, through setting up one-level fermentation cylinder and second grade fermentation cylinder, can carry out degree of depth and shallow fermentation in step to whole avermectin fermentation, improve fermentation efficiency and final fermentation effect, can adsorb leading-in air through setting up the filtration adsorption plate in aseptic filtration box simultaneously, get rid of impurity and moisture wherein, then exterminate the bacterium wherein through sterilization mechanism. The problem of current simple and easy single-stage fermentation structure ferment, because its structure is comparatively simple and easy to have the fermentation time long, can't carry out degree of depth and shallow fermentation simultaneously, the fermentation cylinder does not set up the aseptic air filtration structure supporting with it simultaneously, leads to leading-in air to have miscellaneous fungus to receive the influence to a certain extent in fermentation process, restrain abamectin's production is solved.

Description

Abamectin preparation production system for dogs

Technical Field

The utility model relates to a bio-pharmaceuticals technical field, concretely relates to is an avermectin preparation production system for dog.

Background

The avermectin is a group of sixteen-membered macrolide antibiotics with similar structures generated by fermentation of Streptomyces avermitilis, has strong insecticidal activity, is widely applied to pets such as dogs, cats and the like, and is used for killing parasites on the body surface.

Chinese patent publication No. CN206692635U discloses an avermectin fermentation tank, which is based on a simple single-stage fermentation structure for fermentation, and because the structure is simple and has a long fermentation time, deep and shallow fermentation cannot be performed simultaneously, and no sterile air filtration structure matched with the fermentation tank is provided, the introduced air has mixed bacteria, so that the fermentation process is influenced to a certain extent, and the production of avermectin is inhibited.

SUMMERY OF THE UTILITY MODEL

The utility model provides an above problem, provide an avermectin preparation production system for dog.

The technical scheme is that the production system of the abamectin preparation for the dogs comprises a fermentation structure and a sterile air filtering structure, wherein the fermentation structure comprises a primary fermentation tank, a secondary fermentation tank and a fixed seat, the primary fermentation tank and the secondary fermentation tank are fixed on the fixed seat through a support frame and are communicated through a pipeline, a liquid inlet of the primary fermentation tank is communicated with a fermentation liquid inlet pipe, an air inlet of the primary fermentation tank is communicated with a sterile gas inlet pipe, an air outlet of the secondary fermentation tank is communicated with an exhaust pipe, a liquid outlet of the secondary fermentation tank is communicated with a liquid outlet pipe, the sterile air filtering structure comprises a sterile air filtering box, a filtering and adsorbing plate is arranged in the sterile air filtering box, the sterile air filtering box is divided into an inlet cavity and a sterilizing cavity through the filtering and adsorbing plate, the inlet cavity is connected with an air inlet pipe, and the sterilizing cavity is connected with, the sterilization cavity is internally provided with a sterilization mechanism.

Optionally, a first top cover is arranged at the top of the primary fermentation tank, a first motor and a fermentation liquid inlet pipe are arranged on the first top cover, and a power output end of the first motor is connected with a first stirring shaft inserted into the primary fermentation tank.

Further, the second-stage fermentation tank top is provided with the second top cap, be provided with the second motor on the second top cap, blast pipe and liquid pump, the power take off end of second motor is connected with the second agitator shaft that inserts in the second-stage fermentation tank, the liquid pump input end is connected with first transfer line one end, the liquid pump output end is connected with second transfer line one end, the one-level fermentation tank is inserted to the other end of first transfer line, and be located under the liquid level of zymotic fluid in the one-level fermentation tank, the other end of second transfer line inserts the second-stage fermentation tank, and be located on the liquid level of zymotic.

Optionally, be provided with air duct and connecting pipe between one-level fermentation cylinder and the second grade fermentation cylinder, the air duct both ends communicate with one-level fermentation cylinder upper portion and second grade fermentation cylinder upper portion respectively, the connecting pipe both ends communicate with one-level fermentation cylinder middle part and second grade fermentation cylinder middle part respectively, and the connecting pipe is higher than connecting pipe and second grade fermentation cylinder junction height with the one-level fermentation cylinder junction.

Optionally, a first stirring vane and a second stirring vane are arranged on the first stirring shaft, the first stirring vane is located at the lower part of the first-stage fermentation tank, the second stirring vane is located at the middle part of the first-stage fermentation tank, a third stirring vane is arranged on the second stirring shaft, and the third stirring vane is located at the lower part of the second-stage fermentation tank.

Optionally, a first control valve is arranged on the connecting pipe, a second control valve is arranged on the sterile gas inlet pipe, and a third control valve is arranged on the liquid outlet pipe.

Further, the sterile gas inlet pipe is connected with a gas distribution structure, the gas distribution structure is located at the bottom of the primary fermentation tank, the gas distribution structure is circular, a gas distribution cavity is arranged in the gas distribution structure, and a gas distribution pipe which is uniformly distributed is arranged on the periphery of the gas distribution structure and communicated with the gas distribution cavity.

Optionally, aseptic filtration box is the cylinder structure, and the filtration adsorption plate is the disc structure, filters adsorption plate and aseptic filtration box inner wall contact, and filtration adsorption plate centre of a circle department is provided with first bulge, evenly is provided with the perforation around the first bulge, and the interpolation has filtration adsorption structure in the perforation.

Further, filter the adsorption structure and be the blind hole structure, be provided with air passage in the filtration adsorption structure, filter the adsorption structure and include second bulge, screw thread section and filtration adsorption section, the screw thread section both ends are connected with second bulge and filtration adsorption section respectively, the second bulge is the disc structure, the diameter of second bulge is greater than fenestrate diameter, the screw thread section can be with fenestrate open end screwed connection, there is the clearance in filtration adsorption section and the perforation inner wall.

Optionally, the sterilization mechanism is an ultraviolet sterilization lamp, and the ultraviolet sterilization lamp is attached to the inner wall of the sterilization cavity.

The utility model has the advantages that at least one of the following advantages is included;

1. through setting up primary fermentation jar and second grade fermentation jar, can carry out degree of depth and shallow fermentation in step to whole avermectin fermentation, improve fermentation efficiency and final fermentation effect, can adsorb leading-in air through set up the filtration adsorption plate in aseptic filtration box simultaneously, get rid of impurity and moisture wherein, then exterminate the bacterium wherein through sterilization mechanism.

2. Through setting up specific rabbling mechanism, can carry out necessary stirring when fermenting to the avermectin for the fermentation is more thorough and comprehensive.

3. Through setting up peculiar filtration adsorption structure, can adsorb leading-in air to be convenient for change and follow-up maintenance.

4. The problem of current simple and easy single-stage fermentation structure ferment, because its structure is comparatively simple and easy to have the fermentation time long, can't carry out degree of depth and shallow fermentation simultaneously, the fermentation cylinder does not set up the aseptic air filtration structure supporting with it simultaneously, leads to leading-in air to have miscellaneous fungus to receive the influence to a certain extent in fermentation process, restrain abamectin's production is solved.

Drawings

FIG. 1 is a schematic structural diagram of an avermectin fermentation tank for dogs;

FIG. 2 is a schematic view of the structure of the filtering and adsorbing plate;

FIG. 3 is a schematic diagram of a filtering and adsorbing structure;

FIG. 4 is a schematic structural diagram of another abamectin sterile air filtration structure for dogs;

FIG. 5 is a schematic structural view of an air distribution structure;

labeled as: 1 is a primary fermentation tank, 2 is a secondary fermentation tank, 3 is a first top cover, 4 is a second top cover, 5 is a liquid pump, 6 is a first motor, 7 is a second motor, 8 is a first stirring shaft, 9 is a first stirring rotary vane, 10 is a second stirring rotary vane, 11 is a second stirring shaft, 12 is a third stirring rotary vane, 13 is a fixed seat, 14 is a liquid outlet pipe, 15 is a first control valve, 16 is a gas distribution structure, 17 is a sterile air filter box, 18 is a gas guide pipe, 19 is a sterile gas inlet pipe, 20 is a connecting pipe, 21 is a first liquid conveying pipe, 22 is a second liquid conveying pipe, 23 is an exhaust pipe, 24 is a fermentation liquid inlet pipe, 25 is a second control valve, 26 is a third control valve, 27 is air, 28 is a gas distribution cavity, 29 is a gas distribution pipe, 30 is a filtering and adsorbing plate, 31 is an inlet cavity, 32 is a sterilization cavity, 33 is an ultraviolet sterilization lamp, 34 is a first projecting part, 35 is a gas permeable channel, 36 is a filtering and adsorbing section, 38 is a second bulge, 39 is a thread section, 40 is a through hole, 41 is an auxiliary sterilizing box, 42 is a second ultraviolet sterilizing lamp, 43 is a second sterilizing cavity, and 44 is a sterile gas outlet pipe.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention will be further described in detail with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the scope of the invention.

As shown in fig. 1 to 3, an avermectin preparation production system for dogs comprises a fermentation structure and a sterile air filtration structure, wherein the fermentation structure comprises a primary fermentation tank 1, a secondary fermentation tank 2 and a fixing seat 13, the primary fermentation tank 1 and the secondary fermentation tank 2 are fixed on the fixing seat 13 through a supporting frame, the primary fermentation tank 1 is communicated with the secondary fermentation tank 2 through a pipeline, a liquid inlet of the primary fermentation tank 1 is communicated with a fermentation liquid inlet pipe 24, an air inlet of the primary fermentation tank 1 is communicated with a sterile gas inlet pipe 19, an air outlet of the secondary fermentation tank 2 is communicated with an exhaust pipe 23, a liquid outlet of the secondary fermentation tank 2 is communicated with a liquid outlet pipe 14, the sterile air filtration structure comprises a sterile air filtration box 17, a filtration adsorption plate 30 is arranged in the sterile air filtration box 17, the sterile air filtration box 17 is divided into an inlet cavity 31 and a sterilization cavity 32 through the filtration adsorption plate, the inlet chamber 31 is connected with an air inlet pipe 27, the sterilization chamber 32 is connected with a sterile gas inlet pipe 19, and a sterilization mechanism is arranged in the sterilization chamber 32.

The purpose that designs like this, through setting up first order fermentation cylinder and second grade fermentation cylinder, can carry out degree of depth and light fermentation in step to whole avermectin fermentation, improve fermentation efficiency and final fermentation effect. The filter adsorption plate is arranged in the sterile air filter box, so that introduced air can be adsorbed, impurities and moisture in the air are removed, and bacteria in the air are killed through the sterilization mechanism. Solves the problems that the prior fermentation tank is not provided with a sterile air filtering structure matched with the prior fermentation tank, so that the introduced air has mixed bacteria, thereby being influenced to a certain extent in the fermentation process and inhibiting the generation of abamectin.

In use, compressed air enters the sterile air filter box from the air inlet pipe, enters the cavity first, passes through the filtering and adsorbing plate under the extrusion of subsequent compressed air, adsorbs impurities and moisture in the air under the action of the filtering and adsorbing plate, then enters the sterilization cavity, is provided with the sterilization mechanism in the sterilization cavity, and performs bacterial inactivation on the adsorbed air under the action of the sterilization mechanism, so that the sterile air can be input to the fermentation tank from the sterile gas inlet pipe.

In this embodiment, the top of the primary fermentation tank 1 is provided with a first top cover 3, the first top cover 3 is provided with a first motor 6 and a fermentation liquid inlet pipe 24, and the power output end of the first motor 6 is connected with a first stirring shaft 8 inserted into the primary fermentation tank 1. 2 tops of second grade fermentation cylinder are provided with second top cap 4, be provided with second motor 7 on second top cap 4, blast pipe 23 and liquid pump 5, the power take off end of second motor 7 is connected with the second (mixing) shaft 11 that inserts in the second grade fermentation cylinder 2, the 5 input of liquid pump is connected with first transfer line 21 one end, the 5 output of liquid pump is connected with second transfer line 22 one end, the one-level fermentation cylinder 1 is inserted to the other end of first transfer line 21, and be located under the liquid level of zymotic fluid in the one-level fermentation cylinder 1, second transfer line 22's the other end inserts second grade fermentation cylinder 2, and be located the liquid level of zymotic fluid in the second. Be provided with air duct 18 and connecting pipe 20 between one-level fermentation cylinder 1 and the second grade fermentation cylinder 2, the air duct 18 both ends communicate with 1 upper portion of one-level fermentation cylinder and 2 upper portions of second grade fermentation cylinder respectively, and the connecting pipe 20 both ends communicate with 1 middle part of one-level fermentation cylinder and 2 middle parts of second grade fermentation cylinder respectively, and the connecting pipe 20 is highly higher than the connecting pipe 20 and 2 junctions of second grade fermentation cylinder with 1 junction of one-level fermentation cylinder.

When in use, the fermentation liquor which is uniformly mixed firstly enters the primary fermentation tank through the fermentation liquor inlet pipe, then the sterile gas is introduced into the primary fermentation tank through the sterile gas inlet pipe for fermentation, because the gas guide pipe is arranged between the primary fermentation tank and the secondary fermentation tank, when the sterile gas is introduced into the primary fermentation tank through the sterile gas inlet pipe, redundant gas enters the secondary fermentation tank and is discharged from the gas exhaust pipe, after fermentation is carried out for a certain time, because the sterile gas is continuously introduced, the fermentation degree of the fermentation liquor at the lower part of the primary fermentation tank is shallow, and the fermentation degree of the fermentation liquor at the upper part of the secondary fermentation tank is deep, therefore, a part of the fermentation liquor at the upper part of the primary fermentation tank is pumped into the secondary fermentation tank through the liquid pump, meanwhile, the connecting pipe at the middle, the deep fermentation of the second-stage fermentation tank is realized, the time is short, the fermentation is directly discharged from the liquid outlet pipe after the fermentation is finished, the first-stage fermentation tank is used for shallow fermentation, the fermentation time is long, and the fermentation liquid is introduced into the second-stage fermentation tank after the fermentation is completed to the depth.

In this embodiment, the first stirring shaft 8 is provided with a first stirring vane 9 and a second stirring vane 10, the first stirring vane 9 is located at the lower part of the primary fermentation tank 1, the second stirring vane 10 is located at the middle part of the primary fermentation tank 1, the second stirring shaft 11 is provided with a third stirring vane 12, and the third stirring vane 12 is located at the lower part of the secondary fermentation tank 2.

In the use, through the first stirring rotary vane, second stirring rotary vane and the third stirring rotary vane that set up, can carry out necessary stirring when fermenting the avermectin for the fermentation is more thorough and comprehensive.

In this embodiment, the connecting pipe 20 is provided with a first control valve 15, the sterile gas inlet pipe 19 is provided with a second control valve 25, and the liquid outlet pipe 14 is provided with a third control valve 26.

The purpose of design like this, can carry out reasonable control to connecting pipe, aseptic gaseous intake pipe and drain pipe through first control valve, second control valve and the third control valve that sets up.

As shown in fig. 2, in the embodiment, a specific structure of the gas distribution structure is disclosed, wherein a sterile gas inlet pipe 19 is connected to the gas distribution structure 16, the gas distribution structure 16 is located at the bottom of the primary fermentation tank 1, the gas distribution structure 16 is circular, a gas distribution chamber 28 is arranged in the gas distribution structure 16, and gas distribution pipes 29 which are uniformly distributed and communicated with the gas distribution chamber 28 are arranged at the periphery of the gas distribution structure 16.

In use, in order to improve the cleanliness of the introduced air, the air is introduced from the air inlet pipe 27, enters the sterile air inlet pipe after the adsorption and sterilization effects of the sterile air filtering structure, is introduced into the air distribution chamber of the air distribution structure, and is then discharged from the air distribution pipe communicated with the air distribution chamber.

In this embodiment, sterile air filters box 17 is the cylinder structure, it is the disc structure to filter adsorption plate 30, it contacts with sterile air filters box 17 inner wall to filter adsorption plate 30, it is provided with first bulge 34 to filter the centre of a circle department of adsorption plate 30, evenly be provided with perforation 40 around first bulge 34, it has the filtration adsorption structure to insert in the perforation 40, it is the blind hole structure to filter the adsorption structure, be provided with ventilation channel 35 in the filtration adsorption structure, it includes second bulge 38 to filter the adsorption structure, screw thread section 39 and filtration adsorption section 36, screw thread section 39 both ends are connected with second bulge 38 and filtration adsorption section 36 respectively, second bulge 38 is the disc structure, the diameter of second bulge 38 is greater than the diameter of perforation 40, screw thread section 39 can be connected with the open end screw thread of perforation 40, there is the clearance in filtration adsorption section 36 and the perforation 40 inner wall.

The purpose of design like this is through setting up specific filtration adsorption structure, can adsorb the air of leading-in to be convenient for change and follow-up maintenance.

In the use, the second bulge is handed to the staff, will filter the rotatory installation of adsorption structure to filtering the adsorption plate on through the spiral section, then handheld first bulge installs it on aseptic air filter box inner wall, and the air admission gets into the chamber after, gets into ventilative passageway under the extrusion, passes the filtration adsorption stage, gets into the perforation after the effect of filtration adsorption stage and finally gets into in the sterilization chamber.

In this embodiment, the filtering and adsorbing component in the filtering and adsorbing section 36 is activated carbon or adsorbing cotton, the sterilizing mechanism is an ultraviolet sterilizing lamp 33, and the ultraviolet sterilizing lamp 33 is attached to the inner wall of the sterilizing chamber 32.

The purpose of the design is that large granular substances and moisture in the air can be effectively removed based on the strong adsorption effect of the activated carbon and the adsorption cotton, and then the sterilization is carried out through the ultraviolet sterilizing lamp.

As shown in fig. 4, in this embodiment, another abamectin sterile air filtering structure for dogs is further disclosed, based on the original structure, an auxiliary sterilizing box 41 is added, the auxiliary sterilizing box 41 is communicated with a sterile gas inlet pipe, sterile air discharged from a sterilizing cavity of the sterile air filtering box enters a second sterilizing cavity 43 of the auxiliary sterilizing box through the sterile gas inlet pipe, is further sterilized under the action of a second ultraviolet sterilizing lamp 42, and is discharged from a sterile gas outlet pipe 44 and conveyed to a fermentation tank.

Claims (10)

1. The production system of the avermectin preparation for the dogs is characterized in that: including fermentation structure and sterile air filtration structure, the fermentation structure includes one-level fermentation cylinder (1), second grade fermentation cylinder (2) and fixing base (13), on one-level fermentation cylinder (1) and second grade fermentation cylinder (2) are fixed in fixing base (13) through the support frame, one-level fermentation cylinder (1) and second grade fermentation cylinder (2) pass through the pipeline intercommunication, the inlet and zymotic fluid feed liquor pipe (24) intercommunication of one-level fermentation cylinder (1), the air inlet and the sterile gas intake pipe (19) intercommunication of one-level fermentation cylinder (1), the gas vent and blast pipe (23) intercommunication of second grade fermentation cylinder (2), the liquid outlet and drain pipe (14) intercommunication of second grade fermentation cylinder (2), sterile air filtration structure includes sterile air filtration box (17), is provided with in sterile air filtration box (17) and filters adsorption plate (30), and sterile air filtration box (17) pass through filtration adsorption plate (30) are cut apart sterile air filtration box (17) and are the entering into The sterilization device comprises a cavity (31) and a sterilization cavity (32), wherein the inlet cavity (31) is connected with an air inlet pipe (27), the sterilization cavity (32) is connected with an aseptic gas inlet pipe (19), and a sterilization mechanism is arranged in the sterilization cavity (32).

2. The production system of the avermectin preparation for dogs as claimed in claim 1, wherein the production system comprises: the top of the first-stage fermentation tank (1) is provided with a first top cover (3), the first top cover (3) is provided with a first motor (6) and a fermentation liquor inlet pipe (24), and the power output end of the first motor (6) is connected with a first stirring shaft (8) inserted into the first-stage fermentation tank (1).

3. The production system of the avermectin preparation for dogs as claimed in claim 2, wherein the production system comprises: second stage fermentation cylinder (2) top is provided with second top cap (4), be provided with second motor (7), blast pipe (23) and liquid pump (5) on second top cap (4), the power take off end of second motor (7) is connected with second (mixing) shaft (11) that insert in second stage fermentation cylinder (2), liquid pump (5) input and first transfer line (21) one end are connected, and liquid pump (5) output is connected with second transfer line (22) one end, one-level fermentation cylinder (1) is inserted to the other end of first transfer line (21) to be located under the liquid level of zymotic fluid in one-level fermentation cylinder (1), second stage fermentation cylinder (2) is inserted to the other end of second transfer line (22) to be located on the liquid level of zymotic fluid in second stage fermentation cylinder (2).

4. The production system of avermectin preparation for dogs according to claim 3, wherein the production system comprises: be provided with air duct (18) and connecting pipe (20) between one-level fermentation cylinder (1) and second grade fermentation cylinder (2), air duct (18) both ends communicate with one-level fermentation cylinder (1) upper portion and second grade fermentation cylinder (2) upper portion respectively, connecting pipe (20) both ends communicate with one-level fermentation cylinder (1) middle part and second grade fermentation cylinder (2) middle part respectively, and connecting pipe (20) and one-level fermentation cylinder (1) junction highly be higher than connecting pipe (20) and second grade fermentation cylinder (2) junction height.

5. The production system of avermectin preparation for dogs as claimed in claim 4, wherein the production system comprises: be provided with first stirring vane (9) and second stirring vane (10) on first (mixing) shaft (8), first stirring vane (9) are located the lower part of one-level fermentation cylinder (1), second stirring vane (10) are located the middle part of one-level fermentation cylinder (1), be provided with third stirring vane (12) on second (mixing) shaft (11), third stirring vane (12) are located the lower part of second grade fermentation cylinder (2).

6. The production system of avermectin preparation for dogs as claimed in claim 5, wherein the production system comprises: the device is characterized in that a first control valve (15) is arranged on the connecting pipe (20), a second control valve (25) is arranged on the sterile gas inlet pipe (19), and a third control valve (26) is arranged on the liquid outlet pipe (14).

7. The production system of avermectin preparation for dogs as claimed in claim 6, wherein the production system comprises: the sterile gas inlet pipe (19) is connected with the gas distribution structure (16), the gas distribution structure (16) is positioned at the bottom of the primary fermentation tank (1), the gas distribution structure (16) is circular, a gas distribution cavity (28) is arranged in the gas distribution structure (16), and gas distribution pipes (29) which are uniformly distributed and communicated with the gas distribution cavity (28) are arranged on the periphery of the gas distribution structure (16).

8. The production system of avermectin preparation for dogs as claimed in claim 7, wherein the production system comprises: aseptic filtration box (17) are the cylinder structure, filter adsorption plate (30) are the disc structure, filter adsorption plate (30) and aseptic filtration box (17) inner wall contact, and filter adsorption plate (30) centre of a circle department is provided with first bulge (34), evenly be provided with perforation (40) around first bulge (34), it has the filtration adsorption structure to insert in perforation (40).

9. The production system of avermectin formulations for dogs as claimed in claim 8, wherein: the utility model discloses a filter adsorption structure, including filtration adsorption structure, second bulge (38), screw thread section (39) and filtration adsorption section (36), filtration adsorption structure is provided with air-permeable passage (35) in the blind hole structure, and filtration adsorption structure includes second bulge (38), screw thread section (39) and filtration adsorption section (36), screw thread section (39) both ends are connected with second bulge (38) and filtration adsorption section (36) respectively, and second bulge (38) are the disc structure, and the diameter of second bulge (38) is greater than the diameter of perforation (40), screw thread section (39) can be with the open end screwed connection who perforates (40), there is the clearance in filtration adsorption section (36) and perforation (40) inner wall.

10. The production system of the avermectin preparation for dogs as claimed in claim 1, wherein the production system comprises: the sterilization mechanism is an ultraviolet sterilization lamp (33), and the ultraviolet sterilization lamp (33) is attached to the inner wall of the sterilization cavity (32).

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