CN213068631U - Dry-type immunofluorescence multiband detection device - Google Patents

Dry-type immunofluorescence multiband detection device Download PDF

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Publication number
CN213068631U
CN213068631U CN202021206066.3U CN202021206066U CN213068631U CN 213068631 U CN213068631 U CN 213068631U CN 202021206066 U CN202021206066 U CN 202021206066U CN 213068631 U CN213068631 U CN 213068631U
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connecting rod
sliding ring
channel
detection device
mounting plate
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CN202021206066.3U
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Chinese (zh)
Inventor
顾晓华
时凯强
杨清刚
吴龙
蒋莹
池慧满
王灿
俞建娣
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Hangzhou Weice Biotechnology Co ltd
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Hangzhou Weice Biotechnology Co ltd
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Abstract

The utility model discloses a dry-type immunofluorescence multiband detection device, include: a bracket for placing a test strip; the driving mechanism comprises a motor, a connecting rod, a conductive inner sliding ring and a conductive outer sliding ring, and when the conductive inner sliding ring rotates along with the connecting rod, the conductive outer sliding ring is relatively static; the light path module is arranged above the bracket and comprises a main body which can rotate along with the connecting rod and a plurality of light path structures which are arranged along the circumferential direction of the main body; the detection module comprises a mounting plate which can rotate along with the connecting rod, and a plurality of groups of light sources and photosensitive sensors which are arranged on the mounting plate, wherein the mounting plate is connected with the conductive inner sliding ring; when the motor drives the connecting rod to rotate in the circumferential direction, the main body and the mounting plate rotate along with the connecting rod, and different light path structures are rotated to correspond to the test strips. The utility model can add more test strips to detect wave bands under the condition of unchanged volume, and the switching of the detection wave bands is convenient and flexible; for different detection processes, the stroke of the motor is unchanged, and the consistency of detection results is improved.

Description

Dry-type immunofluorescence multiband detection device
Technical Field
The utility model belongs to the technical field of optical detection, especially, relate to a dry-type immunofluorescence multiband detection device.
Background
POCT detection instruments are popular because of their advantages such as small size, simple operation, and immediate reporting results, especially in small laboratories, outpatients or remote areas. With the development of dry-type immunofluorescence test strips, more and more detection projects are developed, and the development of the detection projects cannot be met by single-waveband detection, which puts demands on multiple-waveband detection on an immunofluorescence analyzer.
Existing detecting instruments on the market at present are mostly multi-channel detecting instruments, or a plurality of optical detecting modules are transversely arranged in a single-channel instrument (namely, sequentially and serially connected together in sequence), on one hand, the two modes increase the volume of the instrument, the miniaturization of the instrument cannot be realized, on the other hand, the total stroke of a motor for dragging a test strip is increased in the transversely arranged mode, the optimal time point for obtaining data can be missed under the influence of motor operation errors and detection time periods, or the starting points for obtaining the data are different, and the data errors are increased.
SUMMERY OF THE UTILITY MODEL
In order to overcome the defects of the prior art, the utility model provides a can carry out the multiband detection, the different wave bands detect and switch conveniently, detect the dry-type immunofluorescence multiband detection device that the uniformity is high.
The utility model provides a technical scheme that its technical problem adopted is: a dry immunofluorescence multi-band detection apparatus, comprising:
a bracket for placing a test strip;
the driving mechanism comprises a motor, a connecting rod connected with the motor, a conductive inner sliding ring connected with the connecting rod, and a conductive outer sliding ring movably sleeved outside the conductive inner sliding ring, wherein when the conductive inner sliding ring rotates along with the connecting rod, the conductive outer sliding ring is relatively static;
the light path module is arranged above the bracket and comprises a main body which can rotate along with the connecting rod and a plurality of light path structures which are arranged along the circumferential direction of the main body;
the detection module comprises a mounting plate which can rotate along with the connecting rod, and a plurality of groups of light sources and photosensitive sensors which are arranged on the mounting plate, wherein the mounting plate is connected with the conductive inner sliding ring;
when the motor drives the connecting rod to rotate in the circumferential direction, the main body and the mounting plate rotate along with the connecting rod, and different light path structures are rotated to correspond to the test strips.
The utility model discloses a plurality of light path structures set up along main part circumference, when connecting rod drive light path module rotates, can accomplish the switching of light path structure, and then realize the switching between a plurality of wave bands, add the volume that detection wave band can not influence detection device, and the motor stroke is unchangeable in the different wave band testing process, and the uniformity of testing result is high.
Furthermore, the lower surface of the conductive inner slip ring is provided with an inner plug-in unit, and the upper surface of the conductive outer slip ring is provided with an outer plug-in unit.
Furthermore, the external plug-in is connected with the signal board flat cable, and the other end of the signal board flat cable is connected with the control module. The conductive inner slip ring can rotate relative to the conductive outer slip ring, the problem that the rotation of a motor can influence wiring when wires are connected is solved, and the conductive inner slip ring can rotate at will.
Furthermore, the upper surface of the mounting plate is provided with a first connector which can be connected with the internal connector in an inserting manner.
Furthermore, the optical path structure comprises an optical path module matching body which is matched with the main body to form a first channel and a second channel, a narrow-band light filtering lens, a dichroic mirror and a convex lens which are arranged in the first channel, a reflector arranged in the second channel and a third channel which is communicated with the first channel and the second channel, wherein the first channel corresponds to the photosensitive sensor, and the second channel corresponds to the light source.
Furthermore, the mounting plate is tightly attached to the main body up and down. The light path module and the detection module can synchronously rotate along with the connecting rod, so that the light source and the light path structure are ensured to be opposite.
Further, the plurality of light path structures are located at a circumferential edge with the axis of the connecting rod as an origin.
Furthermore, a power assembly for driving the bracket to perform reciprocating translation is connected to the bracket. The detection stroke is controlled by the power assembly, so that the consistency of the detection stroke during detection at each time is ensured, and the accuracy of a detection result is improved.
Further, power component includes step motor and the screw rod that links to each other with it, and the tip of screw rod links to each other with the bracket, and the bracket is equipped with the spout that is used for placing the test strip.
Further, the motor, the detection module, the light path module and the bracket are sequentially arranged from top to bottom. Structural design is reasonable, and detection device's whole is small.
The utility model has the advantages that: 1) on the premise of not changing the whole volume of the device, more test strip detection wave bands can be added, and the switching among a plurality of detection wave bands is convenient and flexible; 2) the connecting rod rotates circumferentially to drive the light path module to rotate synchronously, and for the detection processes of different detection wave bands, the stroke of the motor is unchanged, so that the stroke monitoring means of the motor is conveniently increased, and the consistency of the detection results of the test strips of different wave bands is increased; 3) through the design of the conductive inner sliding ring and the conductive outer sliding ring, the problem of signal and power supply connection between the detection module and the control module is solved.
Drawings
Fig. 1 is a perspective view of the present invention.
Fig. 2 is a partial perspective view of the optical path module of the present invention.
Fig. 3 is a perspective view of the conductive inner slip ring and the conductive outer slip ring of the present invention.
Fig. 4 is a perspective view of the conductive outer slip ring of the present invention.
Fig. 5 is a first perspective view of the detection module of the present invention.
Fig. 6 is a second perspective view of the detection module of the present invention.
Detailed Description
In order to make the technical solution of the present invention better understood, the following figures in the embodiments of the present invention are combined to clearly and completely describe the technical solution in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts shall belong to the protection scope of the present invention.
As shown in fig. 1 to 6, a dry-type immunofluorescence multiband detection device comprises a bracket 1 for placing a test strip 2, an optical path module 4 with a plurality of optical path structures 42, a driving mechanism 3 for driving the optical path module 4 to rotate circumferentially, and a detection module 5.
The driving mechanism 3 includes a motor 31, a connecting rod 32 connected to the motor 31, a conductive inner slip ring 33 sleeved outside the connecting rod 32, and a conductive outer slip ring 34 movably sleeved outside the conductive inner slip ring 33. In this embodiment, the motor 31 is a servo motor, the connecting rod 32 is a screw rod of the servo motor, and the inner wall of the conductive inner sliding ring 33 is tightly fitted with the connecting rod 32, so that the conductive inner sliding ring 33 can coaxially rotate along with the connecting rod 32. The conductive outer sliding ring 34 can be fixedly connected with a shell of the detection device, an annular groove is formed in the inner ring of the conductive outer sliding ring 34, an annular flange matched with the annular groove is formed in the outer ring of the conductive inner sliding ring 33, and the annular flange extends into the annular groove, so that when the conductive inner sliding ring 33 rotates along with the connecting rod 32, the conductive outer sliding ring 34 is relatively static.
The lower surface of the conductive inner slip ring 33 is welded with an inner plug 331, and the upper surface of the conductive outer slip ring 34 is welded with an outer plug 341. The external plug 341 of the conductive outer slip ring 34 is connected to the flat cable 61 of the signal board, and the other end of the flat cable 61 of the signal board is connected to the control module 6.
The optical path module 4 is arranged above the bracket 1, and comprises a main body 41 connected with the connecting rod 32 and capable of rotating along with the connecting rod 32, a plurality of optical path structures 42 arranged along the circumference of the main body 41, wherein each optical path structure 42 comprises an optical path module matching body 423 spliced with the main body 41 to form a first channel 421 and a second channel 422, a narrow-band filter lens 424, a dichroic mirror 425 and a convex lens 426 connected in the first channel 421, a reflective mirror 427 connected in the second channel 422, and a third channel 428 transversely communicating the first channel 421 and the second channel 422, the narrow-band filter lens 424, the dichroic mirror 425 and the convex lens 426 are sequentially arranged from top to bottom, and the dichroic mirror 425 and the reflective mirror 427 are positioned at two ends of the third channel 428.
Wherein the first channel 421 corresponds to the light sensor 53, specifically a photodiode light channel; the second channel 422 corresponds to the light source 52, specifically an LED light channel; a multiplexed light channel 429 is formed between the dichroic mirror 425 and the convex lens 426, i.e. the multiplexed light channel 429 and the first channel 421 are coaxially arranged.
In the present embodiment, the plurality of light path structures 42 are distributed on the circumferential edge of the circle with the central axis of the connecting rod 32 as the origin, and the number of the light path structures 42 in the light path module 4 can be changed and the number of the light sources 52 and the photosensitive sensors 53 in the detection module 5 can be correspondingly modified, so as to add or reduce the number of the detection bands.
During detection, the reflective mirror 427, the narrow-band filter lens 424, and the dichroic mirror 425 select corresponding spectral properties according to the wavelength of the light source 52 corresponding thereto; the LED lamp, as a light source, emits light into the second channel 422, through the mirror 427 and dichroic mirror 425 into the multiplexed light channel 429, and is focused on the test strip 2 through the convex lens 426; the fluorescent light emitted by the test strip 2 enters the first channel 421 through the convex lens 426 and the dichroic mirror 425, and is received through the narrow-band filter lens 424.
The detection module 5 comprises a mounting plate 51 connected with the connecting rod 32 and capable of rotating along with the connecting rod 32, and a plurality of groups of light sources 52 and photosensitive sensors 53 arranged on the mounting plate 51, wherein the lower surface of the mounting plate 51 is closely attached to the upper surface and the lower surface of the main body 41, the upper surface of the mounting plate 51 is provided with a first connector 511, and the first connector 511 is connected with an inner connector 331 of the conductive inner sliding ring 33 in an inserting manner without being connected by a lead wire during assembly. The light source 52 and the photosensor 53 are present in pairs, and the photosensor 53 is located in correspondence with the upper end of the first channel 421 in the optical path module 4, and the light source 52 is located in correspondence with the upper end of the second channel 422.
The photosensitive sensors 53 are photodiodes, the photosensitive sensors 53 are of the same specification and model, and the light source 52 is an LED lamp which is selected according to the detection requirement of the test strip and meets the excitation light wavelength of the test strip 2. The function of the detection module 5 is to collect the signal of the photosensitive sensor 53, and transmit the collected signal to the control module 6 through the conductive outer slip ring 34 and the signal plate bus 61, and the control module 6 can control whether the light source 52 is turned on or not. The control module 6 controls the on and off of the motor 31 at the same time.
Of course, a bluetooth low energy module may be disposed on the detection module 5, and the bluetooth low energy module is in communication connection with the control module 6, and at this time, the structures of the conductive inner slip ring 33 and the conductive outer slip ring 34 may be omitted.
A sliding groove 11 with an opening at one end is formed in the bracket 1 along the length direction of the bracket, the test strip 2 is arranged in the sliding groove 11 in a sliding mode, a screw rod 12 is connected to the other side, opposite to the side where the opening of the sliding groove 11 is located, of the bracket 1, and one end of the screw rod 12 is connected with a stepping motor 13. So that the carriage 1 can be translated reciprocally by the cooperation of the stepping motor 13 and the screw 12. The rotation of the stepper motor 13 is also controlled by the control module 6 via the motor lead 14.
Motor 31, detection module 5, light path module 4 and bracket 1 top-down set gradually, and when motor 31 drive connecting rod 32 circumference was rotatory, electrically conductive inner sliding ring 33, detection module 5, light path module 4 rotated along with connecting rod 32, can be synchronous rotation, rotated the multiplexing optical channel 429 of different light path structures 42 to the test strip 2 directly over corresponding position.
The utility model discloses a use method takes three light path structure 42 as an example, includes following steps:
s1, the control module 6 controls the motor 31 to rotate, so that the detection device is restored to the initial state;
marking three optical path structures as a first optical path structure, a second optical path structure and a third optical path structure, wherein the three optical path structures are uniformly distributed on the outer side of the optical path module 4 and on a circle which has the same diameter and is concentric with the optical path module 4, the second optical path structure is positioned at a position of 120 degrees clockwise of the first optical path structure, and the third optical path structure is positioned at a position of 120 degrees anticlockwise of the first optical path structure; and meanwhile, the axis of the multiplexing optical channel of the first optical path structure is ensured to be positioned right above the test strip 2. Since the motor 31 has a feedback function, the control module 6 records the rotation position of the motor 31 at this time as an initial state;
s2, confirming the detection wavelength of the test strip 2, and inserting the test strip 2 into the chute 11 of the bracket 1;
s3, the control module 6 controls the motor 31 to rotate, so that the optical path structure of the optical path module corresponding to the wavelength is located right above the test strip 2, where the control logic of the motor 31 is: if the detection wavelength of the optical path structure one is needed, the motor 31 is not moved; if the detection wavelength of the optical path structure two is needed, the motor 31 drives the connecting rod 32 to rotate 120 degrees clockwise; if the detection wavelength of the optical path structure three is needed, the motor 31 drives the connecting rod 32 to rotate 120 degrees anticlockwise;
s4, the stepping motor 13 drags the bracket 1 to enable the test strip 2 to be positioned at the detection stroke starting position;
s5, the control module 6 controls the light source 52 with the wavelength corresponding to the detection module 5 to light, and starts to collect signals, and meanwhile, the stepping motor 13 drags the bracket 1 to carry out detection travel;
s6, when the test strip 2 reaches the detection stroke end position, the control module 6 controls the detection module 5 to extinguish the light source 52, stops signal acquisition, and drives the bracket 1 to translate and reset by the stepping motor 13;
and S7, analyzing and processing the collected data by the control module 6.
The above detailed description is provided for illustrative purposes, and is not intended to limit the present invention, and any modifications and variations of the present invention are within the spirit and scope of the following claims.

Claims (10)

1. A dry immunofluorescence multi-band detection device, comprising:
a bracket (1) for placing a test strip (2);
the driving mechanism (3) comprises a motor (31), a connecting rod (32) connected with the motor (31), a conductive inner sliding ring (33) connected with the connecting rod (32), and a conductive outer sliding ring (34) movably sleeved outside the conductive inner sliding ring (33), wherein when the conductive inner sliding ring (33) rotates along with the connecting rod (32), the conductive outer sliding ring (34) is relatively static;
the light path module (4) is arranged above the bracket (1) and comprises a main body (41) which can rotate along with the connecting rod (32) and a plurality of light path structures (42) arranged along the circumferential direction of the main body (41);
the detection module (5) comprises a mounting plate (51) which can rotate along with the connecting rod (32), and a plurality of groups of light sources (52) and photosensitive sensors (53) which are arranged on the mounting plate (51), wherein the mounting plate (51) is connected with the conductive inner sliding ring (33);
when the motor (31) drives the connecting rod (32) to rotate in the circumferential direction, the main body (41) and the mounting plate (51) rotate along with the connecting rod (32), and different light path structures (42) are rotated to correspond to the test strips (2).
2. The dry immunofluorescence multiband detection device of claim 1, wherein: the lower surface of the conductive inner sliding ring (33) is provided with an inner plug-in unit (331), and the upper surface of the conductive outer sliding ring (34) is provided with an outer plug-in unit (341).
3. The dry immunofluorescence multiband detection device of claim 2, wherein: the external plug-in (341) is connected with the signal plate flat cable (61), and the other end of the signal plate flat cable (61) is connected with the control module (6).
4. The dry immunofluorescence multiband detection device of claim 2, wherein: the upper surface of the mounting plate (51) is provided with a first connector (511) which can be spliced with the internal connector (331).
5. The dry immunofluorescence multiband detection device of claim 1, wherein: the light path structure (42) comprises a light path module matching body (423) matched with the main body (41) to form a first channel (421) and a second channel (422), a narrow-band filter lens (424), a dichroic mirror (425) and a convex lens (426) which are arranged in the first channel (421), a reflector (427) arranged in the second channel (422), and a third channel (428) communicated with the first channel (421) and the second channel (422), wherein the first channel (421) corresponds to the photosensitive sensor (53), and the second channel (422) corresponds to the light source (52).
6. The dry immunofluorescence multiband detection device of claim 1, wherein: the mounting plate (51) is tightly attached to the main body (41) up and down.
7. The dry immunofluorescence multiband detection device of claim 1, wherein: the plurality of optical path structures (42) are located at circumferential edges with the axis of the link (32) as an origin.
8. The dry immunofluorescence multiband detection device of claim 1, wherein: and the bracket (1) is connected with a power assembly for driving the bracket (1) to perform reciprocating translation.
9. The dry immunofluorescence multiband detection device of claim 8, wherein: the power assembly comprises a stepping motor (13) and a screw rod (12) connected with the stepping motor, the end part of the screw rod (12) is connected with a bracket (1), and the bracket (1) is provided with a sliding groove (11) for placing the test strip (2).
10. The dry immunofluorescence multiband detection device of claim 1, wherein: the motor (31), the detection module (5), the light path module (4) and the bracket (1) are sequentially arranged from top to bottom.
CN202021206066.3U 2020-06-24 2020-06-24 Dry-type immunofluorescence multiband detection device Active CN213068631U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202021206066.3U CN213068631U (en) 2020-06-24 2020-06-24 Dry-type immunofluorescence multiband detection device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202021206066.3U CN213068631U (en) 2020-06-24 2020-06-24 Dry-type immunofluorescence multiband detection device

Publications (1)

Publication Number Publication Date
CN213068631U true CN213068631U (en) 2021-04-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202021206066.3U Active CN213068631U (en) 2020-06-24 2020-06-24 Dry-type immunofluorescence multiband detection device

Country Status (1)

Country Link
CN (1) CN213068631U (en)

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