CN215525819U - Portable fluorescence immunoassay appearance - Google Patents
Portable fluorescence immunoassay appearance Download PDFInfo
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- CN215525819U CN215525819U CN202121016354.7U CN202121016354U CN215525819U CN 215525819 U CN215525819 U CN 215525819U CN 202121016354 U CN202121016354 U CN 202121016354U CN 215525819 U CN215525819 U CN 215525819U
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Abstract
The utility model relates to a portable fluorescence immunoassay analyzer. The device consists of a box-type upper cover, a box-type base body, an image module, a communication module, a processing and displaying module and a power supply module. The box-type upper cover and the box-type base body form a closed box-type structure, and the structure is matched and fixed with the corresponding functional module, so that the functional module can fully play a role. The box-shaped base body comprises a test strip slot, a lighting cavity and a light blocking cover plate. The test strip slot is used for inserting a fluorescence immune test strip; an ultraviolet light source LED lamp is fixed on the front wall of the lighting cavity; the light blocking cover plate is used for reducing stray light from entering the camera. After the test strip is inserted into the test strip slot, the image acquisition module acquires test strip image data under ultraviolet irradiation, and the communication module transmits the test strip image data to the processing and display module in a wireless mode. The analyzer is small and portable, low in cost and simple to operate.
Description
Technical Field
The utility model relates to the technical field of fluorescence analysis equipment, in particular to a portable fluorescence immunoassay analyzer.
Background
Fluorescence analysis refers to a method for qualitative or quantitative analysis by using the fluorescence generated by a certain substance under the irradiation of ultraviolet light to reflect the characteristics of the substance.
FIG. 1 is a schematic diagram of a conventional immunofluorescence chromatography rapid diagnosis test strip. In the using process, a blood sample to be tested is dripped on the sample adding area 11 of the test strip, and after 15 minutes, the quality control line (C line) 121 and the detection line (T line) 122 of the color development area 12 on the test strip can generate a fluorescence reaction under the irradiation of specific ultraviolet fluorescence 131 to emit specific fluorescence 132. The fluorescence value of the detection line (T-line) 122 reflects the concentration of the substance to be detected in the sample, and the magnitude of the fluorescence value is proportional to the concentration of the substance to be detected, and a higher fluorescence value indicates a higher concentration of the substance to be detected in the sample. The control line (line C) 121 is a control zone, and the fluorescence value is a standard fluorescence value. When the quality control line (C line) 121 and the detection line (T line) 122 are both under the same environmental light, the concentration information of the sample to be detected can be obtained qualitatively and semi-quantitatively through the relative relationship between the fluorescence values of the detection line (T line) 122 and the quality control line (C line) 121.
The antibody detection method by the fluorescence immunochromatography method utilizes an immunofluorescence chromatography rapid diagnosis test strip, has high sensitivity and detection precision, but needs to be matched with a fluorescence immunoassay analyzer for use because the detection result cannot be directly observed by naked eyes. However, the conventional fluorescence immunoassay analyzer has a large volume, is inconvenient to carry and has high cost.
Disclosure of Invention
Aiming at the defects in the prior art, the utility model aims to provide a portable fluorescence immunoassay analyzer which has the characteristics of portability, small size, low cost, simple operation and the like.
In order to achieve the purpose, the utility model provides a portable fluorescence immunoassay analyzer, which comprises a box-shaped upper cover, a box-shaped base body, an image acquisition module, a communication module, a processing and displaying module and a power supply module. The box-type upper cover and the box-type base body are used for protecting and mechanically supporting other functional modules and are used for determining the relative positions of the other modules so that the modules can be coordinated and matched with each other. The box-shaped substrate is provided with a test strip slot, and the test strip slot is used for inserting the fluorescence immunity test paper.
Further: the image acquisition module, the communication module and the power module are electrically connected to realize the functions of acquiring and transmitting the image data of the fluorescence immunity test strip.
Further: the box-type upper cover comprises an upper cover shell and a connecting structure. The connecting structure comprises four main connecting columns. The main connecting column is positioned at four corners of the box-type upper cover, and the middle part of the main connecting column is provided with a screw hole for connecting the box-type upper cover and the box-type base body through screws.
It may be preferred that: and a power supply opening is formed in one side of the box-type upper cover and used for exposing the charging interface and the main switch in the power supply module.
The box-shaped base body comprises a test strip slot, an illumination cavity and a light blocking cover plate from bottom to top.
Further: the test strip slot is communicated with the lighting cavity through the light-passing slit. When the test strip is inserted into the test strip slot, the light-passing slit is opposite to the test strip color development area. The method is used for positioning the subsequent processing target area, and meanwhile, the stray light influence can be reduced.
The illumination cavity is enclosed by an illumination wall, a left side wall and a right side wall. And the front side of the illumination cavity is provided with an illumination wall for fixing the ultraviolet source LED lamp. The illumination wall and the test strip clamping groove form an angle of 30-60 degrees, so that energy generated by the ultraviolet light source LED lamp reaches the test strip through the light passing slit as much as possible. And battery grooves are formed in the outer sides of the left side wall and the right side wall and used for fixing lithium batteries of the power supply module.
The light blocking cover plate is arranged above the lighting cavity, a central round hole is arranged on the light blocking cover plate and serves as a light through hole, and the light through hole is located right above the light through slit and used for enabling lighting rays to enter the miniature camera.
It may be preferred that: and the light filter is arranged on the light through hole and used for filtering stray light, so that the detection result is more accurate.
Further: four corners of the inner side of the box-shaped base body are provided with four auxiliary connecting columns. The auxiliary connecting column is internally provided with a through hole matched with the screw hole of the main connecting column and used for inserting a screw for fixing.
Further: the image acquisition module comprises an ultraviolet light source LED lamp, a test strip color development area, an illumination slit, an optical filter and a micro camera. The micro camera is positioned right above the optical filter. The ultraviolet light source LED lamp and the miniature camera are respectively and electrically connected with the power supply module.
The communication module can send the data of the image acquisition module to the processing terminal in a wireless transmission mode. The communication module can be a WiFi module, a Bluetooth module, a radio frequency module and other wireless communication modules. The communication module is electrically connected with the image acquisition module and the power supply module.
The power module comprises a lithium battery and a voltage stabilizing circuit. The power module supplies power to the ultraviolet light source LED lamp, the miniature camera and the communication module. The voltage stabilizing circuit comprises the power supply charging interface and the main switch. The power supply charging interface is used for charging the lithium battery after the box-shaped upper cover and the box-shaped base body are buckled and sealed, and the main switch is used for controlling the operation of the analyzer.
The processing and displaying module comprises a computer, can also be a tablet or a smart phone, can process the data image transmitted by the communication module to obtain a detection result, stores the detection result in a database, and displays the detection result for a user.
The utility model has the beneficial effects that:
(1) the structure design is exquisite, the volume is not more than 6cm multiplied by 8cm, and the device is small, exquisite, portable and convenient to carry;
(2) the cost is low, and each functional module can be matched with and selected from a module with a mature process, so that the cost is greatly reduced;
(3) the operation is simple, the detection result can be obtained by processing the display module through wireless transmission of signals, plugging and unplugging of equipment and only by turning on a main switch and inserting a reagent strip;
(4) the application range can be expanded to communities and families.
Drawings
FIG. 1 is a schematic diagram of a conventional immunofluorescence chromatography rapid diagnostic test strip;
FIG. 2 is a schematic view of the overall structure of the portable fluorescence immunoassay analyzer of the present invention;
FIG. 3 is a schematic structural view of the cassette cover;
FIG. 4 is a schematic view of the construction of the cassette base;
fig. 5 is a schematic diagram of an optical path of the image acquisition module.
Shown in the figure: 1. an immunofluorescence chromatography rapid diagnosis test strip; 11. a test strip sample addition zone; 12. a color development region; 121. a quality control line (line C); 122. a detection line (T-line); 131. ultraviolet fluorescence; 132. reflecting the fluorescence; 2. a box-type upper cover; 21. a main connecting column; 211. a main connecting column screw hole; 22. opening a hole in the power supply; 3. a cassette base; 31. a test strip slot; 32. an illumination cavity; 321. a light-transmitting slit; 322. an illuminating wall; 323. a battery case; 33. a light blocking cover plate; 331. a light through hole; 34. an auxiliary connecting column; 341. a through hole; 4. an image acquisition module; 41. an ultraviolet light source LED lamp; 42. an optical filter; 43. a miniature camera head.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the utility model, and not restrictive of the full scope of the utility model. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
In the description of the present invention, it is to be understood that the terms "center", "upper", "lower", "front", "left", "horizontal", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are used only for convenience in describing the present invention and for simplification of description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
As a matched device of an immunochromatography rapid diagnosis technology, the fluorescence immunoassay analyzer is used in cooperation with a fluorescence immunoassay test strip based on the immunochromatography technology, and can be used for qualitative and semi-quantitative detection of a sample to be detected.
Referring to fig. 2, the portable fluorescence analyzer of the present invention includes a box-shaped upper cover 2, a box-shaped base 3, an image acquisition module 4, a communication module, and a power module. The box-type upper cover 2 and the box-type base body 3 are used for protecting and mechanically supporting other modules and are used for determining the relative positions of different parts of the other modules so as to ensure that the other modules are mutually coordinated and matched. The box-shaped substrate is provided with a test strip slot, and the test strip slot is used for inserting the fluorescent immune test strip. The image acquisition module, the communication module and the power module are electrically connected to realize the functions of acquiring and transmitting the image data of the fluorescence immunity test strip.
The cassette upper cover 2 and the cassette base body 3 are generally obtained by 3D printing.
Referring to fig. 3, four main connection columns 21 are arranged at four corners inside the box-type upper cover 2, and a screw hole 211 is formed in the middle of each main connection column, so that the box-type upper cover 2 and the box-type base body 3 can be fastened and fixed through screws. And a power supply opening 22 is reserved on one side of the upper cover of the shell and used for exposing a charging interface and a main switch in the power supply module so that a user can control the instrument.
Referring to fig. 4, the main structure of the box-shaped substrate 3 from bottom to top is a test strip slot 31, an illumination cavity 32 and a light-blocking cover plate 33.
The test strip slot 31 is used for inserting the fluorescence immunity test strip 1. After the test strip is inserted into the test strip slot 31, the color development area 12 is opposite to the light-passing slit 321. The light passing slit 321 is a through hole communicated with the test strip slot 31 at the bottom of the lighting cavity 32, can effectively shield stray light, and is used for accurately capturing a detection area by the miniature camera.
The front side of the illumination cavity 32 is an illumination wall 322 for fixing the ultraviolet light source LED lamp 41 in the image acquisition module 4. The lighting wall 322 and the test strip slot form a certain angle, generally 30 degrees to 60 degrees, preferably 45 degrees, so as to ensure that the energy of the ultraviolet light source LED lamp 41 reaches the test strip through the light passing slit 321 as much as possible.
The outer side of the left side wall of the lighting cavity 32 is provided with a battery groove 323 for placing a lithium battery in the power module.
A light barrier cover 33 is placed over the illumination cavity 32. The light-blocking cover 33 has a circular hole 331 at the center thereof facing the light-transmitting slit 321 for mounting the filter 42. The filter 42 is used to filter stray light, thereby reducing the influence of stray light on the detection result.
Four auxiliary connecting columns 34 are arranged at four corners of the inner side of the box-shaped base body 3, and a through hole 341 matched with the screw hole 211 of the main connecting column 21 is arranged inside each auxiliary connecting column 34 and used for inserting a screw for fixing.
The image acquisition module 4 relates to an ultraviolet light source LED lamp 41, a color development area 12 of the test strip 1, a light transmission slit 321, a light filter 42 and a micro camera 43. Reference is made to figure 5 relating to the optical path. The ultraviolet light source LED lamp 41 emits ultraviolet fluorescence 131 to irradiate the test strip color development area 12 through the light passing slit 321, so as to excite the test strip color development area 12 to perform fluorescence reaction, and the reflected specific fluorescence 132 enters the micro camera 43 through the light passing slit 321 and the optical filter 42. The micro-camera 43 and the accessory circuit are used for collecting the specific fluorescence 132 image reflected by the test strip color development area 12. Wherein the micro camera is opposite to the filter 42.
The communication module mainly comprises a communication chip and an auxiliary circuit. The communication mode generally adopts wireless communication modes such as WiFi, Bluetooth, radio frequency and the like. The communication module is electrically connected with the image acquisition module to obtain images shot by the miniature camera 43, and the image data is transmitted outwards for the processing terminal to receive.
The power module mainly comprises a lithium battery and a voltage stabilizing circuit. The power supply module supplies power to the ultraviolet light source LED lamp 41, the miniature camera 43 and the communication module. The voltage stabilizing circuit comprises a power supply charging interface and a main switch. The power supply charging interface is used for charging the lithium battery after the box-shaped upper cover 2 and the box-shaped base body 3 are buckled and sealed, and the main switch is used for controlling the operation of the analyzer.
The parts used in the utility model can be purchased from the market, the specific connection mode of each part adopts the mature conventional means of sticking, riveting and the like in the prior art, the parts adopt the conventional types in the prior art, and the circuit connection adopts the conventional connection mode in the prior art, so that the details are not described.
The foregoing shows and describes the general principles, essential features, and advantages of the utility model. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and the preferred embodiments of the present invention are described in the above embodiments and the description, and are not intended to limit the present invention. The scope of the utility model is defined by the appended claims and equivalents thereof.
Claims (14)
1. A portable fluorescence immunoassay appearance which characterized in that: the analyzer consists of a box-shaped upper cover, a box-shaped base body, an image acquisition module, a communication module, a processing and displaying module and a power supply module; the box-type upper cover and the box-type base body can be connected into a compact box-type structure through screws, and the image acquisition module, the communication module and the power supply module are positioned in the box-type structure; the box-type structure matrix is provided with a test strip slot; the test strip slot is used for inserting a fluorescence immunity test strip.
2. The portable fluoroimmunoassay analyzer of claim 1, wherein: the image acquisition module, the communication module and the power module are electrically connected to realize the functions of acquiring and transmitting the image data of the fluorescence immunity test strip.
3. The portable fluoroimmunoassay analyzer of claim 2, wherein: the box-type upper cover comprises an upper cover shell and a connecting structure; the connecting structure comprises four main connecting columns; the main connecting column is positioned at four corners of the box-type upper cover, and the middle part of the main connecting column is provided with a screw hole for connecting the box-type upper cover and the box-type base body through screws.
4. The portable fluoroimmunoassay analyzer of claim 3, wherein: and one side of the box-type upper cover shell is provided with a power supply opening.
5. The portable fluoroimmunoassay analyzer of claim 4, wherein: the box-shaped base body comprises a test strip slot, an illumination cavity and a light blocking cover plate from bottom to top.
6. The portable fluoroimmunoassay analyzer of claim 5, wherein: the test strip slot is communicated with the lighting cavity through a light-passing slit; when the test strip is inserted into the test strip slot, the light-passing slit is opposite to the test strip color development area.
7. The portable fluoroimmunoassay analyzer of claim 6, wherein: the lighting cavity is surrounded by a lighting wall and a battery jar; the front side of the illumination cavity is provided with an illumination wall for fixing an ultraviolet light source LED lamp; the lighting wall is at an angle of 30 to 60 degrees to the test strip slot; and one side of the lighting cavity is provided with a battery jar for fixing the lithium battery.
8. The portable fluoroimmunoassay analyzer of claim 7, wherein: the battery jar is located the illumination cavity outside space.
9. The portable fluoroimmunoassay analyzer of claim 8, wherein: the upper side of the illumination cavity is provided with a light blocking cover plate, a central round hole is arranged on the light blocking cover plate and serves as a light through hole, and the light through hole is located right above the light through slit and used for reflecting fluorescence to enter the miniature camera.
10. The portable fluoroimmunoassay analyzer of claim 9, wherein: and the light-transmitting hole is provided with a light filter for filtering stray light.
11. The portable fluoroimmunoassay analyzer of claim 10, wherein: four auxiliary connecting columns are arranged at four corners of the inner side of the box-type base body; the auxiliary connecting column is internally provided with a through hole matched with the screw hole of the main connecting column and used for inserting a screw for fixing.
12. The portable fluoroimmunoassay analyzer of claim 11, wherein: the image acquisition module comprises an ultraviolet light source LED lamp, a test strip color development area, an illumination slit, an optical filter and a micro camera; the micro camera is positioned right above the optical filter; the ultraviolet light source LED lamp and the miniature camera are respectively and electrically connected with the power supply module.
13. The portable fluoroimmunoassay analyzer of claim 12, wherein: the communication module can send the data of the image acquisition module to the processing terminal in a wireless transmission mode.
14. The portable fluoroimmunoassay analyzer of claim 13, wherein: the power supply module comprises a lithium battery and a voltage stabilizing circuit; the power supply module supplies power to the ultraviolet light source LED lamp, the miniature camera and the communication module; the voltage stabilizing circuit comprises a power supply charging interface and a main switch; the power supply charging interface is used for charging the lithium battery after the box-shaped upper cover and the box-shaped base body are buckled and sealed, and the main switch is used for controlling the operation of the fluorescence analyzer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121016354.7U CN215525819U (en) | 2021-05-13 | 2021-05-13 | Portable fluorescence immunoassay appearance |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121016354.7U CN215525819U (en) | 2021-05-13 | 2021-05-13 | Portable fluorescence immunoassay appearance |
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| Publication Number | Publication Date |
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| CN215525819U true CN215525819U (en) | 2022-01-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202121016354.7U Expired - Fee Related CN215525819U (en) | 2021-05-13 | 2021-05-13 | Portable fluorescence immunoassay appearance |
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| CN (1) | CN215525819U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114563582A (en) * | 2022-02-21 | 2022-05-31 | 姜籽宇 | Portable immunity analyzer and manufacturing method thereof |
-
2021
- 2021-05-13 CN CN202121016354.7U patent/CN215525819U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114563582A (en) * | 2022-02-21 | 2022-05-31 | 姜籽宇 | Portable immunity analyzer and manufacturing method thereof |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20220114 |
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| CF01 | Termination of patent right due to non-payment of annual fee |