CN213060850U - Solid-liquid flash type helicobacter pylori detection chamber - Google Patents
Solid-liquid flash type helicobacter pylori detection chamber Download PDFInfo
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- CN213060850U CN213060850U CN202021304600.4U CN202021304600U CN213060850U CN 213060850 U CN213060850 U CN 213060850U CN 202021304600 U CN202021304600 U CN 202021304600U CN 213060850 U CN213060850 U CN 213060850U
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Abstract
The utility model relates to the technical field of medical detection instruments, in particular to a solid-liquid flash type helicobacter pylori detection chamber which has simple and reliable structure, good light-closing effect, shortened detection period and reduced detection cost, the solid-liquid flash type helicobacter pylori detection chamber comprises a base, an inner cavity of which is provided with two detectors, and a feeding mechanism which is arranged on the base and communicated with the inner cavity of the base, wherein the feeding mechanism comprises a mounting seat provided with a feeding channel, a bottom sealing plate which is arranged at the input end of the feeding channel and is in sliding connection with the mounting seat, a top sealing plate fixedly connected with one surface of the bottom sealing plate, which is back to the mounting seat, and provided with an opening communicated with the feeding channel, and the driving device is used for driving the bottom sealing plate to move, the bottom sealing plate is used for plugging the feeding channel under the control of the driving device, the top sealing plate is used for plugging a gap between the bottom sealing plate and the feeding channel, and the two detectors are matched with each other and oppositely arranged to detect a sample entering the feeding channel.
Description
Technical Field
The utility model relates to the technical field of medical detection equipment, in particular to a solid-liquid flash type helicobacter pylori detection chamber.
Background
Helicobacter pylori infection is an important index for judging stomach diseases of subjects, and is an important means for examining malignant diseases such as gastric cancer. In the course of detection of helicobacter pylori, urea is administered orally to the subject mainly14C]Capsule for collecting gas exhaled by the subject, wherein if helicobacter pylori exists in stomach of the subject, the stomach is rich in high-activity urease, and further the urease catalyzes urea to rapidly hydrolyze into NH4 +And H14CO3 -The latter is absorbed into the blood through the lung to14CO2Breath form, collection of breath samples and qualitative analysis14CO2And (4) judging whether the test subject is infected by the helicobacter pylori. In particular, the method of manufacturing a semiconductor device,14the sample C is collected in a solid flash or liquid flash sample bottle, the radioactive sample is converted into photons after energy transfer in a scintillation substance, an optical signal is converted into an electrical signal through a photomultiplier, and the electrical signal is analyzed by a circuit system to form a result. However, the conventional detection chamber has a slightly complicated structure in the process of processing the light-blocking process, and the samples need to be continuously and manually transferred to the detection chamber, so that the failure rate of the instrument, the detection period of the samples, the labor cost and the like are increased substantially.
SUMMERY OF THE UTILITY MODEL
Therefore, it is necessary to provide a solid-liquid flash type helicobacter pylori detection chamber which has a simple and reliable structure, a good light-blocking effect, a short detection period and a low detection cost, and aims to solve the technical problems of complex structure, insufficient light-blocking effect, long detection period and high detection cost.
The utility model provides a flash-type pylorus helicobacterium of solid-liquid detects room, this flash-type pylorus helicobacterium of solid-liquid detects room include its inner chamber be equipped with the detector the base and install in the base and with the pan feeding mechanism of the inner chamber intercommunication of base, pan feeding mechanism including set up the mount pad of pan feeding passageway, set up in the input of pan feeding passageway, with mount pad sliding connection's end shrouding, with back on the end shrouding one side fixed connection of mount pad and be equipped with the open-ended top shrouding of pan feeding passageway intercommunication, and be used for the drive arrangement of end shrouding motion, the end shrouding is used for the shutoff under drive arrangement's control the pan feeding passageway, the top shrouding is used for the shutoff end shrouding with space between the pan feeding passageway, the detector is used for detecting and puts into the sample of base inner chamber.
In one embodiment, the detector is a photomultiplier tube.
In one embodiment, the inner cavity of the base is provided with a light guide, which is located between the two detectors.
In one of the embodiments, the light guide is made of POM.
In one embodiment, the top closure plate has a width greater than a width of the bottom closure plate.
In one embodiment, the mounting seat is provided with a guide groove matched with the bottom sealing plate, and the guide groove is used for limiting the movement path of the bottom sealing plate.
In one embodiment, the inner surface of the guide slot is provided with a sensing device for detecting the open or closed state of the bottom sealing plate.
In one embodiment, the driving device includes a motor and a screw rod drivingly connected to the motor, and one end of the screw rod, which is far from the motor, is connected to the bottom sealing plate, so as to drive the bottom sealing plate to move.
In one embodiment, the motor is a stepper motor.
The solid-liquid flash type helicobacter pylori detection chamber is simple and reliable in structure, few in parts, capable of achieving first heavy blocking of the input end of the feeding channel by arranging the bottom sealing plate, and capable of achieving second heavy blocking of the input end of the feeding channel by arranging the top sealing plate to block a gap between the bottom sealing plate and the feeding channel, and the double sealing plates improve the light blocking effect of the feeding channel and ensure that a sample is not interfered by external light during detection, so that the detection reliability is improved, and the accuracy of a detection result is improved; adopt drive arrangement to promote the bottom closure board and open and shut, replaced manual work, promoted the efficiency that detects the operation, shortened detection cycle and be favorable to reducing the cost that detects the operation.
Drawings
FIG. 1 is a schematic view showing the construction of a solid-liquid flash type helicobacter pylori detection chamber in a state shown in one embodiment;
FIG. 2 is a schematic structural view of the solid-liquid flash type helicobacter pylori detection chamber in another state in one embodiment;
FIG. 3 is a schematic diagram showing the explosion structure of the solid-liquid flash type helicobacter pylori detection chamber in one embodiment;
FIG. 4 is a schematic diagram of the operation of the sensing device of the solid-liquid flash type helicobacter pylori detection chamber of the present invention in a first state;
FIG. 5 is a schematic diagram of the operation of the sensing device in another state of the solid-liquid flash type helicobacter pylori detection chamber of the present invention.
Detailed Description
In order to make the above objects, features and advantages of the present invention more comprehensible, embodiments of the present invention are described in detail below with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. The present invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein, as those skilled in the art will be able to make similar modifications without departing from the spirit and scope of the present invention.
Referring to fig. 1 to 3 together, the present invention provides a solid-liquid flash type helicobacter pylori detection chamber 10 with simple structure, good light-blocking effect, shortened detection period and reduced detection cost, the solid-liquid flash type helicobacter pylori detection chamber 10 comprises a base 100 having a detector 200 in an inner cavity thereof, and a feeding mechanism 300 mounted on the base 100 and communicated with the inner cavity of the base 100, the feeding mechanism 300 comprises a mounting seat 310 having a feeding channel 311, a bottom sealing plate 320 disposed at an input end of the feeding channel 311 and slidably connected to the mounting seat 310, a top sealing plate 330 fixedly connected to a surface of the bottom sealing plate 320 opposite to the mounting seat 310 and having an opening 331 communicated with the feeding channel 311, and a driving device 340 for driving the bottom sealing plate 320 to move, the bottom sealing plate 320 is used for blocking the feeding channel 311 under the control of the driving device 340, the top sealing plate 330 is used for blocking a gap between the bottom sealing plate 320 and the feeding channel 311, the probe 200 is used to detect a sample placed in the cavity of the base 100.
The implementation of the utility model discloses a solid-liquid flash type helicobacter pylori detection chamber 10, its simple structure is reliable, the part is less, realize the first heavy shutoff to pan feeding passageway 311 input through setting up bottom seal plate 320, set up top seal plate 330 and seal the space between bottom seal plate 320 and pan feeding passageway 311, realize the second heavy shutoff to pan feeding passageway 311 input, double seal plate has promoted the light-blocking effect of pan feeding passageway 311, do not receive the interference of external light when guaranteeing to detect the sample, thereby improved the reliability of detection, promoted the accuracy of detection result; adopt drive arrangement 340 to promote the bottom closure plate 320 and open and shut, replaced manual work, promoted the efficiency that detects the operation, shortened detection cycle and be favorable to reducing the cost that detects the operation.
The base 100 is used to house the probe 200 and provide a detection space for the sample. In an embodiment, the base 100 includes a cube-shaped seat body 110 and two cylinders 120 symmetrically installed on two sides of the seat body 110 and having sealed ends, an inner cavity of the seat body 110 is respectively communicated with the feeding channel 311 and the two cylinders 120 and is used for accommodating a sample bottle to be detected and containing a sample, so as to provide a place for detecting the sample, and the design of the cube-shaped structure is beneficial to increasing the contact area between the seat body 110 and an external installation surface, thereby improving the installation stability of the detection chamber 10. A detector 200 is provided in each of the two cylinders 120 for jointly detecting a sample disposed in the interior of the housing 110.
Further, in an embodiment, the inner cavity of the base 100 is provided with a limiting member 130 for positioning the sample bottle, so that after the sample bottle is fed into the inner cavity of the base 100 through the feeding channel 311, the sample bottle is not easily shaken under the constraint of the limiting member 130, and positioning can be quickly achieved, so that the detector 200 detects a sample in the sample bottle, and detection efficiency is improved. In one embodiment, the inner cavity of the base 100 is provided with a light guide 140, the light guide 140 being located between the two detectors 200, preferably the light guide 140 is made of POM or teflon. In other words, the light guide 140 is embedded in the inner cavity of the seat body 110 and is used for guiding photons generated in the sample detection process, and the light guide 140 made of POM and the light guide 140 made of teflon have good light guiding effects and good photon guiding performance, so that the loss of photons in the detection process can be reduced, and thus, the quantity of photons recognized by the detector 200 is increased, and the sensitivity and the reliability of the detector 200 can be improved.
The detector 200 is used for detecting in a sample14C content, in one embodiment, the detector 200 is a photomultiplier tube. Specifically, before detection, the sample bottle is filled with carbon dioxide gas capable of being collected14C, the reactant and the reactant release photons after reaction, the photons are captured by the photomultiplier when migrating in the inner cavity of the seat body 110, and the photons are analyzed by the photomultiplier through a circuit system to convert photoelectric signals into corresponding electric signals to be output, so that indication is performed14The content of C. In the present embodiment, two photomultiplier tubes are used for the seat body 11014The content of C is measured, and the pair is realized14The content of C is in accordance with judgment, so that the influence of external interference signals is favorably eliminated, and the reliability of the detection result is improved.
The feeding mechanism 300 is used for guiding the sample bottles and plugging the detection space in the seat body 110, so that external light is prevented from entering the detection space in the detection process, and further the detection result is prevented from being interfered. Referring to fig. 3 again, in an embodiment, the mounting base 310 is formed with a guiding groove 312 engaged with the bottom sealing plate 320 for limiting a moving path of the bottom sealing plate 320. So, the bottom sealing plate 320 is attached to the inner surface of the guide groove 312 under the control of the driving device 340, and is always moved along the extending direction of the guide groove 312, so that the bottom sealing plate 320 is prevented from shaking during the moving process, and the reliability of the bottom sealing plate 320 for plugging the input end of the feeding channel 311 is improved.
Further, referring to fig. 3, 4 and 5, in one embodiment, the inner surface of the guide slot 312 is provided with a sensing device 350 for detecting the open or closed state of the bottom sealing plate 320. Specifically, the sensing device 350 includes a first sensor 351 and a second sensor 352 disposed on the mounting base 310 and having sensing ends respectively facing the guiding slot 312, and a controller (not shown) for receiving signals transmitted by the first sensor 351 and the second sensor 352 and controlling the driving device 340 to move forward and backward, the first sensor 351 and the second sensor 352 are sequentially disposed along a direction away from the output end of the driving device 340, the sensing end of the second sensor 352 corresponds to a side surface of the bottom sealing plate 320 close to the driving device 340 when the bottom sealing plate 320 completely seals the input end of the feeding channel 311, and a distance difference between the sensing end of the first sensor 351 and the sensing end of the second sensor 352 is equal to an aperture of the input end of the feeding channel 311, i.e., a width of the input end. Thus, when the bottom sealing plate 320 is driven by the driving device 340 to move and the end of the bottom sealing plate is detected by the second sensor 352, the second sensor 352 sends a signal to the controller, so that the controller controls the driving device 340 to stop continuing to push the bottom sealing plate 320, and the bottom sealing plate 320 completely seals the input end of the feeding channel 311, that is, the bottom sealing plate 320 moves forward to the maximum displacement. When the end of the bottom sealing plate 320 is detected by the first sensor 351, the first sensor 351 sends a signal to the controller, so that the controller controls the driving device 340 to stop pulling the bottom sealing plate 320, the bottom sealing plate 320 completely leaves the input end of the feeding channel 311, that is, the bottom sealing plate 320 moves in the reverse direction to the maximum displacement, so as to facilitate loading the sample bottle into the inner cavity of the seat body 110 through the feeding channel 311. It should be noted that, in this embodiment, the end of the bottom sealing plate 320 refers to a side surface of the bottom sealing plate 320 adjacent to the driving device 340, and is not described herein again.
The top sealing plate 330 is used to seal the gap between the bottom sealing plate 320 and the feeding channel 311 and the guiding groove 312, so as to improve the light-blocking effect at the input end of the feeding channel 311. In one embodiment, the top sealing plate 330 is fixedly connected to the bottom sealing plate 320 by screws, but other fixing methods may be used. It should be noted that, when the detection chamber 10 is used, when the bottom sealing plate 320 retracts to completely leave the feeding channel 311 under the action of the driving device 340, the opening 331 of the top sealing plate 330 is communicated with the feeding channel 311, so as to place the sample bottle to be detected into the inner cavity of the seat body 110; when the bottom sealing plate 320 completely blocks the feeding passage 311 under the action of the driving device 340, the end of the top sealing plate 330 away from the opening 331 covers the output end of the driving device 340. In an embodiment, the width of the top sealing plate 330 is greater than the width of the bottom sealing plate 320, so that when the bottom sealing plate 320 seals the feeding channel 311, the top sealing plate 330 seals the gap between the connection between the bottom sealing plate 320 and the feeding channel 311 and the gap between the connection between the bottom sealing plate 320 and the guiding groove 312, thereby ensuring the light-blocking effect of the feeding channel 311 and improving the reliability of the detection result.
The driving motor 341 is used for controlling the motion track of the bottom sealing plate 320. In one embodiment, the driving device 340 includes a motor 341 and a screw 342 drivingly connected to the motor 341, and one end of the screw 342, which is far away from the motor 341, is connected to the bottom sealing plate 320 for driving the bottom sealing plate 320 to move. Preferably, motor 341 is a stepper motor. Specifically, the screw 342 penetrates through the slider 344 and is engaged with the slider 344, the slider 344 is further slidably connected with the guide rail 343 disposed on the mounting base 310, the motor 341, the screw 342, the guide rail 343 and the slider 344 cooperate to form a linear module, when the motor 341 works under the control of the controller, the rotating shaft of the motor 341 rotates and drives the screw 342 to rotate synchronously, thereby driving the slider 344 and the bottom sealing plate 320 fixedly connected with the slider 344 to be far away from or close to the input end of the feeding channel 311 along the guide rail 343, in other words, the bottom sealing plate 320 is pushed to be far away from or close to the input end of the feeding channel 311, so as to open and close the input end of the feeding channel 311, thereby facilitating the sample detection operation.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only represent some embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.
Claims (9)
1. A solid-liquid flash type helicobacter pylori detection chamber (10) is characterized by comprising a base (100) with an inner cavity provided with a detector (200) and a feeding mechanism (300) which is arranged on the base (100) and communicated with the inner cavity of the base (100),
pan feeding mechanism (300) including offering mount pad (310) of pan feeding passageway (311), set up in the input of pan feeding passageway (311), with mount pad (310) sliding connection's end shrouding (320), with end shrouding (320) go up dorsad the one side fixed connection of mount pad (310) and be equipped with top shrouding (330) of opening (331) of pan feeding passageway (311) intercommunication, and be used for the drive end shrouding (320) drive arrangement (340) of motion, end shrouding (320) are used for the shutoff under drive arrangement's (340) control pan feeding passageway (311), top shrouding (330) are used for the shutoff end shrouding (320) with space between pan feeding passageway (311), detector (200) are used for detecting and put into the sample of base (100) inner chamber.
2. The solid-liquid flash helicobacter pylori detection chamber (10) according to claim 1, wherein the detector (200) is a photomultiplier tube.
3. The solid-liquid flash helicobacter pylori detection chamber (10) according to claim 1, wherein the inner cavity of the base (100) is provided with a light guide (140), the light guide (140) being located between the two detectors (200).
4. The solid-liquid flash helicobacter pylori detection chamber (10) according to claim 3, characterized in that the light guide (140) is made of POM.
5. The solid-liquid flash helicobacter pylori detection chamber (10) according to claim 1, wherein the top sealing plate (330) has a width greater than a width of the bottom sealing plate (320).
6. The solid-liquid flash helicobacter pylori detection chamber (10) according to claim 1, wherein the mounting seat (310) is provided with a guide groove (312) which is matched with the bottom sealing plate (320) and used for limiting a movement path of the bottom sealing plate (320).
7. The solid-liquid flash helicobacter pylori detection chamber (10) according to claim 6, wherein the inner surface of the guide groove (312) is provided with a sensing device (350) for detecting the open or closed state of the bottom closure plate (320).
8. The solid-liquid flash helicobacter pylori detection chamber (10) according to claim 1, wherein the driving device (340) comprises a motor (341) and a lead screw (342) in driving connection with the motor (341), and one end of the lead screw (342) far away from the motor (341) is connected with the bottom sealing plate (320) and used for driving the bottom sealing plate (320) to move.
9. The solid-liquid flash helicobacter pylori detection chamber (10) according to claim 8, wherein the motor (341) is a stepper motor.
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CN202021304600.4U CN213060850U (en) | 2020-07-03 | 2020-07-03 | Solid-liquid flash type helicobacter pylori detection chamber |
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CN202021304600.4U CN213060850U (en) | 2020-07-03 | 2020-07-03 | Solid-liquid flash type helicobacter pylori detection chamber |
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Effective date of registration: 20220721 Address after: 518118 No. 5, Lutian Road, Jinsha community, Kengzi street, Pingshan District, Shenzhen, Guangdong Province Patentee after: SHENZHEN ZHONGHE HEADWAY BIO-SCI & TECH Co.,Ltd. Patentee after: Limited by Share Ltd. China Address before: 518057 6th floor, building r1-b, South District, high tech Industrial Park, Shennan Avenue, Nanshan District, Shenzhen City, Guangdong Province Patentee before: SHENZHEN ZHONGHE HEADWAY BIO-SCI & TECH Co.,Ltd. |