CN108732365B - Automatic card formula helicobacter pylori tester - Google Patents

Automatic card formula helicobacter pylori tester Download PDF

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Publication number
CN108732365B
CN108732365B CN201710261288.1A CN201710261288A CN108732365B CN 108732365 B CN108732365 B CN 108732365B CN 201710261288 A CN201710261288 A CN 201710261288A CN 108732365 B CN108732365 B CN 108732365B
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China
Prior art keywords
measuring chamber
automatic
card
opening
helicobacter pylori
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CN201710261288.1A
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CN108732365A (en
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姚子伦
李磊
罗武燕
张超
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China Tongfu Co., Ltd
Shenzhen Zhonghe Headway Bio Sci & Tech Co ltd
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Shenzhen Zhonghe Headway Bio Sci & Tech Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0412Block or rack elements with a single row of samples

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The application relates to an automatic card formula helicobacter pylori (Hp) tester includes: the material tray (4) is provided with a plurality of clamping grooves (3) which are used for accommodating the gas collecting card (5) side by side; the measuring chamber (13) is internally provided with a Geiger Miller tube (12), the top end of the measuring chamber (13) is provided with a sample sending port, and the measuring chamber is internally provided with an accommodating space; the automatic sample feeding system (8) comprises a lead screw (801) arranged in parallel under the material tray (4) and a moving bin (802) capable of moving the gas collecting card (5) from the material tray (4) to the measuring chamber (13) along the lead screw (801) in a reciprocating mode; the measuring chamber (13) is located directly below the automatic sample introduction system (8). According to the invention, a plurality of sample cards to be detected can be placed on the material tray in batches, and the material bin is moved back and forth through the forward and reverse rotation of the stepping motor to perform sampling so as to perform automatic batch detection, so that the working efficiency is improved, and meanwhile, the control is convenient.

Description

Automatic card formula helicobacter pylori tester
Technical Field
The invention relates to the field of medical equipment, in particular to an automatic cassette type helicobacter pylori (Hp) tester for a helicobacter pylori urea breath test.
Background
Helicobacter pylori (Hp) infection can be diagnosed by a variety of methods, among which14C-Urea breath test (14C-UBT) is an atraumatic, painless detection method. The presence of urease in the human stomach is evidence of the presence of H.pylori, since urease is not present in mammalian cells and the presence of other species of bacteria has not been found in the stomach. Is orally administered to patients14After C-urea, if helicobacter pylori exists in the stomach, the produced urease can rapidly decompose urea into carbon dioxide and ammonia gas, and the carbon dioxide enters the lung through blood and is discharged out of the body. To exhale by the patient14CO2After collection, the helicobacter pylori is measured on an instrument, and then whether the helicobacter pylori is infected in the stomach or not can be diagnosed.
The gas collecting card 5 is an expired gas collecting device which contains alkaline CO2Absorbing substance, the subject blows air to the air blowing port of the air collecting card 5, and the indicator in the indicating window of the card 5 to be collected changes from orange redStopping blowing when the color turns yellow, CO2The gas collector is saturated and then the gas collection card 5 is placed on a helicobacter pylori (Hp) card tester with geiger miller 12 to detect radioactivity. However, the existing instrument can only store and detect one sample, which wastes time and labor and has low working efficiency.
Disclosure of Invention
The technical problem to be solved by the invention is as follows: provides an automatic cassette helicobacter pylori (Hp) tester,
the technical scheme adopted by the invention for solving the technical problems is as follows: there is provided an automatic helicobacter pylori (Hp) test meter, comprising:
the material tray is provided with a plurality of clamping grooves for accommodating the gas collecting cards side by side;
the measuring chamber is internally provided with a Geiger Miller tube, the top end of the measuring chamber is provided with a sample sending port, and the measuring chamber is internally provided with an accommodating space;
the automatic sample feeding system comprises a lead screw arranged in parallel under the material tray and a movable bin capable of moving the gas collecting card from the material tray to the measuring chamber along the lead screw in a reciprocating motion manner; the measuring chamber is positioned right below the automatic sample feeding system.
In the automatic cassette type helicobacter pylori (Hp) tester provided by the invention, a first reflective sensor is arranged on the movable bin and is aligned with the clamping groove on the material tray.
In the automatic cassette type helicobacter pylori (Hp) tester provided by the invention, the movable stock bin comprises an upper end opening and a lower end opening, a first opening and closing device is arranged on the upper end opening, and a second opening and closing device is arranged on the lower end opening.
In the automatic cartridge type helicobacter pylori (Hp) tester provided by the invention, the first opening and closing device comprises a first electromagnet and a first sliding pin, and the first sliding pin is slidably arranged at the upper end opening; the second opening and closing device comprises a second electromagnet and a second sliding pin, and the second sliding pin is slidably arranged at the lower end opening.
In the automatic clamping type helicobacter pylori (Hp) tester provided by the invention, the lower end of the clamping groove is provided with a discharge hole, each discharge hole is provided with a push-pull deflector rod, the first electromagnet drives the push-pull deflector rod to open the discharge hole, and the push-pull deflector rod pulls the first sliding pin to open the upper end opening of the movable bin.
In the automatic cassette type helicobacter pylori (Hp) tester provided by the invention, a third opening and closing device is arranged at the lower port of the measuring chamber and comprises a third electromagnet and a third sliding pin, the third sliding pin is slidably arranged at the lower port of the measuring chamber, and the third electromagnet drives the third sliding pin to open the lower port of the measuring chamber.
The automatic clamping type helicobacter pylori (Hp) tester provided by the invention further comprises a gas collection card recovery box, wherein the gas collection card recovery box is positioned right below the measuring chamber, and a second reflection type sensor is arranged on the inner wall of the gas collection card recovery box.
In the automatic cartridge type helicobacter pylori (Hp) tester provided by the invention, the automatic sample feeding system further comprises a stepping motor for driving the moving bin to reciprocate along the lead screw.
The implementation of the invention can achieve the following beneficial effects: according to the invention, a plurality of sample cards to be detected can be placed on the material tray in batches, and the moving bin is moved back and forth through the forward and reverse rotation of the stepping motor to perform sampling so as to perform automatic batch detection, so that the working efficiency is improved, and meanwhile, the control is convenient.
Drawings
The invention will be further described with reference to the accompanying drawings and examples, in which:
FIG. 1 is a schematic view showing the overall construction of an automatic helicobacter pylori (Hp) test device of the present invention;
FIG. 2 is a schematic view showing the internal structure of the automatic helicobacter pylori (Hp) test device of the present invention;
FIG. 3 is a schematic view showing an angle of an automatic sample introduction system of the automatic helicobacter pylori (Hp) test device of the present invention;
FIG. 4 is a schematic view showing another angle of the automatic sample introduction system of the automatic helicobacter pylori (Hp) test device of the present invention;
in the figure: 1. functional area, 2, casing, 3, draw-in groove, 4, charging tray, 5, gas collection card, 6, upper cover, 7, step motor, 8, autoinjection device, 801, lead screw, 802, removal feed bin, 803, upper end opening, 804, lower extreme opening, 805, first reflection type sensor, 810, first device that opens and shuts, 820, second device that opens and shuts, 811, first electro-magnet, 812, first sliding pin, 821, second electro-magnet, 822, second sliding pin, 9, main control board, 10, output port, 11, backshell, 12, geiger miller count pipe, 13, measuring chamber, 130, third device that opens and shuts, 131, third electro-magnet, 132, third sliding pin, 14, gas collection card collection box, 15, push-and-pull pole, 16, printer, 17, LCD screen.
Detailed Description
For a more clear understanding of the technical features, objects and effects of the present invention, embodiments of the present invention will now be described in detail with reference to the accompanying drawings.
General card formula helicobacter pylori (Hp) tester can only once insert a sample, needs the special messenger to guard, waits to detect and has accomplished the back and change the expiratory card by hand, and complex operation is great to the sample size, needs the unit inefficiency that detects in batches, in order to improve work efficiency, needs a card formula helicobacter pylori (Hp) tester once to insert a plurality of samples, carries out the sampling measurement automatically.
Fig. 1 shows a schematic view of the overall structure of the automatic helicobacter pylori (Hp) test device of the present invention, which, as shown in fig. 1, includes a functional area 1, a housing 2, a tray 4, an upper cover 6, and a printer 16. The upper cover 6 can be opened and closed, the upper cover 6 is opened to form the charging tray 4 in a cuboid shape, and a plurality of clamping grooves 3 used for containing the gas collecting card 5 are arranged on the charging tray 4. The number of the card slots 3 can be 24 in the figure, and can also be other numbers, and the number of the card slots is determined by the length of the tray 4 and the interval of the card slots 3. An automatic sample introduction system 8 (see fig. 2) is arranged below the clamping groove 3, a measuring chamber 13 (see fig. 2) is arranged below the automatic sample introduction system 8, the automatic sample introduction system 8 moves the gas collecting card 5 from the tray 4 to the measuring chamber 13, and a detection result is displayed by the functional area 1 of the functional area 1 and printed by a printer 16.
In another preferred embodiment of the present invention, the automatic helicobacter pylori (Hp) card tester further comprises a gas collection card recycling box 14, the gas collection card recycling box 14 is located right below the measuring chamber 13, a second reflective sensor is disposed on an inner wall of the gas collection card recycling box 14, and the second reflective sensor detects whether the number of the gas collection cards 5 in the gas collection card recycling box 14 reaches a rated number, so as to avoid that the detected gas collection cards 5 cannot smoothly fall into the gas collection card recycling box 14 due to too many gas collection cards 5 in the gas collection card recycling box 14.
Fig. 2 shows a schematic diagram of an internal structure of the automatic helicobacter pylori (Hp) tester of the present invention, as shown in fig. 2, an automatic sample injection system 8 is located below the card slot 3, a measurement chamber 13 is located below the automatic sample injection system 8, the automatic sample injection system 8 can move back and forth, the gas collection card 5 is moved from the card slot 3 to the automatic sample injection system 8 by using the self-gravity of the gas collection card 5, then the automatic sample injection system 8 is moved to the measurement chamber 13 to place the gas collection card 5, and the detection of the gas collection card 5 is completed. The automatic sample introduction system 8 repeatedly moves the gas collecting card 5 from the material tray 4 to the measuring chamber 13, and batch detection can be automatically completed. The automatic cassette helicobacter pylori (Hp) tester of the embodiment comprises a main control board 9 and an output port 10, wherein the rear cover is opened, a detection chamber is in signal connection with the main control board 9, and the main control board 9 receives a detection signal obtained by a Geiger Maitreya tube 12 to perform calculation and result analysis. The output port 10 is used for connecting a PC, the output port 10 is electrically connected with the main control board 9, the detection result of the main control board 9 is connected with the PC through the output port 10, and a user directly inquires detection data through a network.
In another preferred embodiment of the present invention, the functional area 1 includes a touch-equipped liquid crystal panel, and the touch-equipped liquid crystal panel 17 and the printer 16 are disposed on the main body case 2 and electrically connected to the main control board 9, respectively. The touch liquid crystal screen 17 improves the man-machine interchange function, the high pressure required by the normal work of the Geiger Muller tube 12 can be adjusted through the touch liquid crystal screen 17, and the work of single machine detection, result query and the like can also be realized through the touch liquid crystal screen 17. The main control board 9 prints the detection result through the printer 16, and a third reflective sensor (not shown in the figure) is arranged in a paper loading slot of the printer 16 and is used for detecting paper shortage. The main control board 9 can judge the working state of the printer 16 and the working state of the Geiger Muller tube 12, and is convenient for debugging and after-sale service; the operation can be realized through software of an upper computer, and the operation is convenient and quick.
FIG. 3 is a schematic view showing an angle structure of an automatic sample injection system 8 of the automatic helicobacter pylori (Hp) tester of the present invention, as shown in FIG. 3, a tray 4, the automatic sample injection system 8, and a measuring chamber 13 are arranged from top to bottom, a Geiger Miller tube 12 is arranged inside the measuring chamber 13, a sample feeding port is arranged at the top end of the measuring chamber 13, and an accommodating space is arranged inside the measuring chamber; the gas collecting card 5 firstly enters the automatic sampling system 8 from the material tray 4, and the automatic sampling system 8 moves to the measuring chamber 13 to place the gas collecting card 5 to finish detection.
The automatic sample feeding system 8 comprises a lead screw 801 and a moving bin 802, wherein the lead screw 801 is arranged under the tray 4 in parallel, and the moving bin 802 can move back and forth along the lead screw 801 to move the gas collecting card 5 from the tray 4 to the measuring chamber 13. The movable bin 802 has a flat inner accommodating cavity for accommodating the air collecting card 5, and when the movable bin 802 moves along the lead screw 801 to a position right below a certain card slot 3, the air collecting card 5 falls into the movable bin 802 due to the gravity action of the air collecting card 5. Preferably, the first reflective sensor 805 is arranged on the mobile bin 802, the first reflective sensor 805 is aligned with the card slot 3 on the charging tray 4 to detect whether the gas collecting card 5 exists in the card slot 3, when the mobile bin 802 moves to a certain card slot 3 along the lead screw 801, if the first reflective sensor 805 receives a reflection signal, it indicates that the gas collecting card 5 exists in the card slot 3, and the mobile bin 802 can receive the gas collecting card 5 therein; if the first reflective sensor 805 does not receive a reflected signal, indicating that there is no air-collecting card 5 in the card slot 3, the mobile magazine 802 moves to the next card slot 3 position.
Fig. 4 shows a schematic structural diagram of another angle of the automatic sample feeding system 8 of the automatic helicobacter pylori (Hp) tester of the present invention, as shown in fig. 4, the mobile bin 802 includes an upper opening 803 and a lower opening 804, a first opening and closing device 810 is disposed on the upper opening 803, and a second opening and closing device 820 is disposed on the lower opening 804. When the movable bin 802 moves to a certain card slot 3 along the lead screw 801, the presence of the gas collecting card 5 in the card slot 3 is detected, that is, the first opening and closing device 810 can be opened to take the gas collecting card 5 in the card slot, then the movable bin 802 moves to the position of the measuring chamber 13 along the lead screw 801, the second opening and closing device 820 is opened, and the gas collecting card 5 falls into the measuring chamber 13 from the lower end opening 804.
Preferably, the automatic sample feeding system 8 of the automatic cassette helicobacter pylori (Hp) tester of the embodiment specifically works as follows: the first opening and closing device 810 comprises a first electromagnet 811 and a first sliding pin 812, wherein the first sliding pin 812 is slidably arranged in the upper end opening 803; the second opening and closing device 820 includes a second electromagnet 821 and a second sliding pin 822, and the second sliding pin 822 is slidably disposed in the lower end opening 804. The lower end of the clamping groove 3 is a discharge hole, each discharge hole is provided with a push-pull deflector rod 15, the first electromagnet 811 drives the push-pull deflector rod to open the discharge hole, and the push-pull deflector rod 15 pulls the first sliding pin 812 to open the upper end opening 803 of the movable bin 802.
When the movable bin 802 moves to a certain card slot 3 along the screw 801, the push-pull lever 15 on the position of the card slot 3 just falls into the middle of the first electromagnet 811 and the first sliding pin 812, the first reflective sensor 805 detects that the gas collecting card 5 exists in the card slot 3, the first electromagnet 811 can be started, the first electromagnet 811 drives the push-pull lever to open the discharge port, the push-pull lever 15 pulls the first sliding pin 812 to open the upper end opening 803 of the movable bin 802, and the gas collecting card 5 can smoothly fall into the movable bin 802. Then the first opening and closing device 810 is closed, the first sliding pin 812 slides back to the upper end opening 803 of the moving bin 802, the moving bin 802 moves to the position of the measuring chamber 13 along the lead screw 801, the second opening and closing device 820 is opened, the second electromagnet 821 works to control the second sliding pin 822 to move away from the lower end opening 804 of the moving bin 802, the gas collection card 5 falls into the measuring chamber 13 from the lower end opening 804, and the measurement is started.
Preferably, the automatic sample feeding system 8 in the above embodiment further includes a stepping motor 7 for driving the moving bin 802 to reciprocate along the lead screw 801, and the stepping motor 7 is connected to the lead screw 801, and drives the moving bin 802 to reciprocate between the card slot 3 and the measuring chamber 13 by forward rotation and reverse rotation.
According to the automatic clamping type helicobacter pylori (Hp) tester, the automatic sampling system 8 is used for placing the plurality of gas collecting cards 5 on the material tray 4 at one time, the automatic sampling system 8 is controlled by the main control board 9 to respectively convey the plurality of gas collecting cards 5 to the measuring chamber 13, samples are automatically detected, and labor is saved.
While the present invention has been described with reference to the embodiments shown in the drawings, the present invention is not limited to the embodiments, which are illustrative and not restrictive, and it will be apparent to those skilled in the art that various changes and modifications can be made therein without departing from the spirit and scope of the invention as defined in the appended claims.

Claims (7)

1. An automatic helicobacter pylori of card formula tester, characterized by, includes:
the material tray (4) is provided with a plurality of clamping grooves (3) which are used for accommodating the gas collecting card (5) side by side;
the measuring chamber (13) is internally provided with a Geiger Miller tube (12), the top end of the measuring chamber (13) is provided with a sample sending port, and the measuring chamber is internally provided with an accommodating space;
the automatic sample feeding system (8) comprises a lead screw (801) arranged in parallel under the material tray (4) and a moving bin (802) capable of moving the gas collecting card (5) from the material tray (4) to the measuring chamber (13) along the lead screw (801) in a reciprocating mode; the measuring chamber (13) is positioned right below the automatic sampling system (8);
the mobile storage bin (802) comprises an upper end opening (803) and a lower end opening (804), a first opening and closing device (810) is arranged on the upper end opening (803), and a second opening and closing device (820) is arranged on the lower end opening (804);
when the mobile bin (802) moves to a certain card slot (3) along the lead screw (801), the existence of the gas collecting card (5) in the card slot (3) is detected, namely the first opening and closing device (810) is opened to collect the gas collecting card (5) into the card slot, then the mobile bin (802) moves to the position of the measuring chamber (13) along the lead screw (801), the second opening and closing device (820) is opened, and the gas collecting card (5) falls into the measuring chamber (13) from the lower end opening (804).
2. The automated helicobacter pylori cartridge tester according to claim 1, wherein a first reflective sensor (805) is provided on the mobile magazine (802), the first reflective sensor (805) being aligned with the card slot (3) on the tray (4).
3. The automatic helicobacter pylori tester as claimed in claim 2, wherein the first opening and closing means (810) comprises a first electromagnet (811), a first sliding pin (812), the first sliding pin (812) being slidably disposed at the upper end opening (803); the second opening and closing device (820) comprises a second electromagnet (821) and a second sliding pin (822), and the second sliding pin (822) is slidably arranged at the lower end opening (804).
4. The automatic helicobacter pylori cassette tester according to claim 3, wherein the lower end of the clamping groove (3) is provided with a discharge hole, each discharge hole is provided with a push-pull lever (15), the first electromagnet (811) drives the push-pull lever to open the discharge hole, and the push-pull lever (15) pulls the first sliding pin (812) to open the upper end opening (803) of the movable bin (802).
5. The automatic helicobacter pylori tester according to claim 1, wherein a third opening and closing device (130) is disposed at a lower port of the measuring chamber (13), the third opening and closing device (130) comprises a third electromagnet (131) and a third sliding pin (132), the third sliding pin (132) is slidably disposed at the lower port of the measuring chamber (13), and the third electromagnet (131) drives the third sliding pin (132) to open the lower port of the measuring chamber (13).
6. The automatic helicobacter pylori card tester according to claim 1, further comprising a gas collection card recovery box (14), wherein the gas collection card recovery box (14) is located right below the measuring chamber (13), and a second reflective sensor is disposed on an inner wall of the gas collection card recovery box (14).
7. The automated helicobacter pylori cartridge tester according to claim 1, wherein the autosampler system (8) further comprises a stepper motor (7) driving the moving magazine (802) to and fro along the lead screw (801).
CN201710261288.1A 2017-04-20 2017-04-20 Automatic card formula helicobacter pylori tester Active CN108732365B (en)

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CN109342482B (en) * 2018-11-16 2024-05-28 深圳市福瑞康科技有限公司 Scintillation detection device and method and application thereof
CN109557121B (en) * 2018-12-12 2024-02-27 深圳市福瑞康科技有限公司 Detection module and detection equipment
CN109542186B (en) * 2018-12-12 2024-06-25 深圳市福瑞康科技有限公司 Cabinet main body, cabinet and scintillation detection device
CN109655478B (en) * 2018-12-12 2024-02-27 深圳市福瑞康科技有限公司 Scintillation detection device

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CN205152230U (en) * 2015-10-31 2016-04-13 安徽养和医疗器械设备有限公司 Three calories of formula helicobacter pylori detectors
CN205898829U (en) * 2016-07-27 2017-01-18 广州万孚生物技术股份有限公司 A advance to clamp and put for fluorescent quantitation analysis appearance

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CN104724454A (en) * 2013-12-24 2015-06-24 广州万孚生物技术股份有限公司 Reagent card settling transmission device
CN203903210U (en) * 2014-06-13 2014-10-29 陕西科技大学 Hopper device with stock bin capable of being automatically opened and closed
CN104049077A (en) * 2014-06-27 2014-09-17 安徽养和医疗器械设备有限公司 Helicobacter pylori detector
CN204581282U (en) * 2015-03-27 2015-08-26 安徽养和医疗器械设备有限公司 With the cassette detector of automatic sampling apparatus
CN205152230U (en) * 2015-10-31 2016-04-13 安徽养和医疗器械设备有限公司 Three calories of formula helicobacter pylori detectors
CN205898829U (en) * 2016-07-27 2017-01-18 广州万孚生物技术股份有限公司 A advance to clamp and put for fluorescent quantitation analysis appearance

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