CN213010396U

CN213010396U - Radioactive drug product bottling and transferring system and conveying device

Info

Publication number: CN213010396U
Application number: CN202020454055.0U
Authority: CN
Inventors: 李杨; 黄勇; 曾松柏; 雷嗣烦; 陈林
Original assignee: Chengdu Gaotong Isotope Co ltd Cnnc
Current assignee: Chengdu Gaotong Isotope Co ltd Cnnc
Priority date: 2020-03-31
Filing date: 2020-03-31
Publication date: 2021-04-20
Anticipated expiration: 2030-03-31

Abstract

The utility model relates to a radiopharmaceutical apparatus for producing's field particularly, relates to a radiopharmaceutical product bottling transit system and conveyor, cooperates in the lead pot and uses. Radioactive drug product bottling transfer system and conveyor include transporting hot chamber, conveyor, elevating gear and manipulator. Transfer hot chamber bottom cooperation lead jar and be provided with the butt joint hole to make the top of lead jar can stretch into the butt joint hole and make the lead jar top laminate in transferring hot chamber bottom. The manipulator sets up inside transporting the hot chamber. The lifting device is arranged right below the butt joint hole. The conveying device is matched with the lifting device to be arranged, so that the conveying device can convey the lead can to the upper part of the lifting device or convey the lead can at the upper end of the lifting device to the next station. Elevating gear makes lead jar and transports the butt joint of hot room, and after placing the medicine bottle, elevating gear leaves the lead jar and transports the hot room. The lead can does not enter the hot chamber in the process of placing the medicine bottle, so that aerosol in the hot chamber is prevented from leaking.

Description

Radioactive drug product bottling and transferring system and conveying device

Technical Field

The utility model relates to a radiopharmaceutical apparatus for producing's field particularly, relates to a radiopharmaceutical product bottling transit system and conveyor.

Background

As radiopharmaceuticals are used more widely in the diagnosis and treatment of various diseases, their production and demand have increased year by year. However, due to the special properties of radiopharmaceuticals, the production process must not only take radiation safety into account, but also comply with GMP-related requirements of pharmaceuticals, so that the degree of automation in the production process is generally not high at present.

In the production process of the radioactive drugs, drug solution is subpackaged and sealed in a tube-type antibiotic glass bottle in a hot chamber, then the subpackaged product bottle is filled into a shielding lead tank, and finally the shielding lead tank is transferred out of the hot chamber for external packaging.

In order to ensure the cleanliness level of the pharmaceutical production environment, the prior art generally adopts the following methods:

1. repeatedly cleaning and wiping an empty shielding lead can outside a clean area;

2. after cleaning, placing the shielding lead tank in a delivery window with a self-cleaning function between a non-clean area and a clean area for disinfection and sterilization through a manual mode or a transfer trolley;

3. after the disinfection is finished, the shielding lead tank is transferred to a medicine production line by a production person in the clean area through manual carrying or using a transfer trolley;

4. in a medicine production line, a manufacturer opens a door of a transfer hot chamber to transfer shielding lead cans into the hot chamber one by one, or opens a channel at the bottom of the hot chamber, and pushes the shielding lead cans into the hot chamber one by one through a lifting device;

5. taking down a lead plug of the shielding lead tank, placing the lead plug on a workbench, bottling the subpackaged product into the lead tank, and covering the lead plug again;

6. transferring the lead cans filled with the cans out of the hot chamber again, and transferring the lead cans into a transfer window for self-cleaning;

7. and finally, the shielding lead cans filled with the medicines are transferred to an outer package for subsequent operation by workers outside the clean area through manual carrying or using a transfer trolley.

For the radioactive medicines with a slightly large production capacity, the transportation of all products cannot be completed at one time, production personnel need to repeatedly lift and transport a large number of shielding lead cans for completion, and in addition, the shielding lead cans are heavy, so the labor intensity of the production personnel is quite large. Moreover, in the clean area of pharmaceutical production, only 2-4 operators are generally allowed to enter simultaneously for reasons of radiation safety. For personnel in the clean areas, the production, the sub-packaging, the canning and other operations with higher requirements are required to be carried out in each production, all the shielding lead cans are required to be frequently transported, the labor intensity is higher, and the risk of other operations causing errors is increased.

Meanwhile, the shielding lead can needs to wholly or partially enter the transfer hot chamber in the operation process, so that the risk that the lead can is polluted by radioactivity is increased. In addition, in the process of entering, a shielding door or a lifting channel of the hot chamber needs to be opened repeatedly, and the generation amount of radioactive aerosol in an operation place can be increased, so that the irradiation dose in production personnel is increased.

And thirdly, according to the current operation flow, in the operation process of production personnel in the clean area, other workers outside the clean area can only wait passively, cannot cooperate simultaneously, and the overall efficiency is relatively low.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a radiopharmaceutical product bottling transfer system and conveyor, it can avoid the lead can to get into transports the hot chamber, and then fine aerosol that avoids transporting in the hot chamber leaks.

The embodiment of the utility model is realized like this:

a transport system for bottled cans of radiopharmaceutical products is matched with a lead can for use; the radioactive drug product bottled tank transferring system comprises a transferring hot chamber, a conveying device, a lifting device and a manipulator; the bottom of the transfer hot chamber is provided with a butt joint hole matched with the lead can, so that the top end of the lead can extend into the butt joint hole and the top of the lead can is attached to the bottom of the transfer hot chamber;

the manipulator is arranged inside the transfer hot chamber; the lifting device is arranged right below the butt joint hole;

the conveying device is matched with the lifting device to be arranged, so that the conveying device can convey the lead can to the position above the lifting device or convey the lead can at the upper end of the lifting device to the next station.

Further, the top end of the lead can is arranged in a circular truncated cone shape; the lower extreme cooperation of butt joint hole the top of lead can is provided with the flaring section to make the roof of lead can laminate in the inner wall of flaring section.

Further, the inner wall of flaring section is provided with sealed the pad.

Further, the manipulator comprises a lead plug taking and placing assembly and a medicine bottle taking and placing assembly; the lead plug taking and placing assembly comprises a lifting cylinder vertically arranged right above the butt joint hole and a clamping cylinder connected to the lower end of the lifting cylinder.

A conveying device, which is matched with the radioactive drug product bottled tank transferring system for use; the conveying device comprises a plurality of carrying assemblies, a power assembly and a transmission assembly in transmission connection with the power assembly; the plurality of carrying assemblies are connected to the transmission assembly, so that the transmission assembly drives the plurality of carrying assemblies to move;

the carrying assembly is provided with an avoidance hole matched with the lifting device, so that the lifting device can penetrate through the avoidance hole; the object carrying assembly is further matched with the avoiding hole and provided with an object carrying tray, so that the object carrying tray can be placed in the avoiding hole.

Further, the transmission assembly comprises a transmission chain and a plurality of transmission gears; the transmission chain is matched with the transmission gears and is arranged in an annular shape;

the carrying assembly comprises a carrying rack and a plurality of rollers connected with the carrying rack; the avoiding hole is arranged on the object carrier.

Further, the carrying tray is provided with a placing groove matched with the lead can, so that the lead can be contained in the placing groove.

The utility model has the advantages that:

when the lead can is used, a producer places the lead can above the conveying device. The conveying device conveys the lead can to the position below the transfer hot chamber and enables the lead can to face the butt joint hole. Subsequently, the lifting device is raised and lifts the lead can. In the process of lifting the lead tank, the opening of the lead tank is communicated with the butt joint hole; meanwhile, the top end of the lead can is tightly attached to the outer wall of the bottom of the transfer hot chamber, so that the lead can and the transfer hot chamber are sealed. Subsequently, the sealing cover of the transfer hot chamber arranged at the butt joint hole is automatically opened, so that the interior of the transfer hot chamber is communicated with the interior of the lead tank. The manipulator inside the transfer hot chamber takes off the lead plug and places the medicine bottle inside the lead can. After the medicine bottle is placed into the lead can, the opening of the lead can is covered by the lead plug through the mechanical arm; meanwhile, the sealing cover of the transfer hot chamber blocks the butt joint hole. Finally, the lifting device is lowered, so that the lead can is placed on the surface of the conveying device. At the moment, the conveying device can convey the lead cans filled with the medicine bottles to the next station.

This kind of radiopharmaceutical product bottling transfer system's advantage lies in:

1. the worker only needs to place the lead can into the conveying device or take the lead can off from the conveying device. Greatly reducing the labor intensity of production personnel. Meanwhile, the amount of manual labor is reduced, the number of personnel can be further reduced, and the production cost is reduced.

2. The lead can main part no longer gets into transports the hot chamber, only lead stopper part can get into the hot chamber through the butt joint hole of hot chamber bottom in, nevertheless can not effectively reduce the risk that lead can surface radioactivity stains with hot chamber surface direct contact when the operation yet. Repeated wiping and disinfection of the surface of the lead can are not needed, and only simple cleaning is needed.

3. When some production personnel enter the operation of the product bottling tank, other workers also carry out subsequent operation on the finished product lead tank, the assembly line operation is basically realized, and the production efficiency is greatly improved.

4. In the production process, only the butt joint hole at the bottom of the transfer hot chamber can be opened temporarily in the process of entering and exiting the lead can, and the diameter of the butt joint hole is very small, so that the possibility of leakage of radioactive aerosol is basically avoided, and the risk that production personnel are irradiated by internal rays is reduced.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.

Fig. 1 is an isometric view of a radiopharmaceutical product bottled tank transfer system provided in an embodiment of the present invention;

FIG. 2 is a cross-sectional view of a radiopharmaceutical product vial transport system according to an embodiment of the present invention;

FIG. 3 is a top view of a radiopharmaceutical product bottle transport system according to an embodiment of the present invention;

FIG. 4 is a schematic view of the lead can and the transfer heating chamber according to the embodiment of the present invention;

fig. 5 is a schematic view of the lead can, the lifting device and the conveying device according to the embodiment of the present invention.

Icon:

1-transfer hot chamber, 11-butt joint hole, 111-flaring section, 12-sealing cover, 2-conveying device, 21-carrying tray, 211-placing groove, 22-carrying frame, 221-avoiding hole, 23-roller, 3-lifting device, 31-lifting cylinder, 32-lifting plate, 4-mechanical arm, 41-lifting cylinder, 5-lead can, 51-lead plug, 6-transmission assembly, 61-transmission chain and 62-transmission gear.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention, as generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate the position or positional relationship based on the position or positional relationship shown in the drawings, or the position or positional relationship which is usually placed when the product of the present invention is used, and are only for convenience of description and simplification of the description, but do not indicate or imply that the device or element referred to must have a specific position, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.

Example (b):

referring to fig. 1 to 5, the present embodiment provides a system for transferring bottled radiopharmaceutical products, which is used in conjunction with a lead can 5. Radioactive medicine product bottled jar transfer system includes transports hot chamber 1, conveyor 2, elevating gear 3 and manipulator 4. The transfer heat chamber 1 is a common heat chamber, and a robot 4 is provided inside the transfer heat chamber. The operator can operate the robot 4 to perform production in the hot room. In this embodiment, the manipulator 4 is used to clamp the medicine bottle filled with the medicine and place the medicine bottle in the lead can 5 for shielding. In order to pick up the lead plug 51 of the lead can 5, the manipulator 4 further comprises a lead plug 51 picking and placing assembly. The lead plug 51 taking and placing assembly comprises a lifting cylinder 41 vertically arranged right above the butting hole 11 and a clamping cylinder connected to the lower end of the lifting cylinder 41.

The bottom of the transfer hot chamber 1 is matched with the lead can 5 and is provided with a butt joint hole 11, so that the top end of the lead can 5 can extend into the butt joint hole 11 and the top of the lead can 5 is attached to the bottom of the transfer hot chamber 1. In practice, the top of the lead can 5 is tapered. The lower end of the butt joint hole 11 is provided with a flaring section 111 matched with the top end of the lead can 5, so that the top wall of the lead can 5 can be attached to the inner wall of the flaring section 111. This allows the conical top wall of the lead can 5 to be exactly flush with the inner wall of the flared end 111 after the lead can 5 is butted against the butting hole 11.

The interior of the transfer hot chamber 1 is also provided with a sealing cover 12 matched with the butt joint hole 11. The seal cap 12 is an electrically driven seal cap 12. The operator can operate the opening and closing of the sealing lid 12.

The lifting device 3 is arranged right below the butt joint hole 11. The conveying device 2 is matched with the lifting device 3 to be arranged, so that the conveying device 2 can convey the lead can 5 to the position above the lifting device 3 or convey the lead can 5 at the upper end of the lifting device 3 to the next station. The lifting device 3 is a vertically arranged jacking cylinder 31. A lift plate 32 is provided at the top end of the cylinder rod of the lift cylinder 31.

In use, a manufacturer places the lead can 5 above the conveyor 2. The conveying device 2 conveys the lead can 5 to the position below the transfer hot chamber 1, and the lead can 5 is opposite to the butt joint hole 11. Subsequently, the lifting device 3 is raised and lifts the lead can 5. During the process of lifting the lead can 5, the opening of the lead can 5 is communicated with the butt joint hole 11. Meanwhile, the top end of the lead can 5 is tightly attached to the outer wall of the bottom of the transfer hot chamber 1, so that the lead can 5 and the transfer hot chamber 1 are sealed. Subsequently, the sealing cover 12 of the transfer heating chamber 1 provided at the butting hole 11 is opened, so that the inside of the transfer heating chamber 1 and the inside of the lead can 5 are communicated. The robot 4 inside the transfer chamber 1 removes the lead stopper 51 and places the vial inside the lead can 5. After the medicine bottle is put into the lead can 5, the manipulator 4 covers the opening of the lead can 5 with the lead stopper 51. Meanwhile, the sealing cover 12 of the transfer hot chamber 1 blocks the butt hole 11. Finally, the lifting device 3 is lowered so that the lead can 5 is placed on the surface of the conveying device 2. At this time, the conveying device 2 can convey the lead can 5 with the medicine bottles to the next station.

1. the operator only has to place the lead can 5 on the conveyor 2 or remove the lead can 5 from the conveyor 2. Greatly reducing the labor intensity of production personnel. Meanwhile, the amount of manual labor is reduced, the number of personnel can be further reduced, and the production cost is reduced.

2. The main body of the lead can 5 does not enter the transfer hot chamber 1 any more, only the lead plug 51 part can enter the hot chamber through the butt joint hole 11 at the bottom of the hot chamber, but can not directly contact with the surface of the hot chamber during operation, and the risk of radioactive contamination on the surface of the lead can 5 is effectively reduced. Repeated wiping and disinfection of the surface of the lead can 5 are not needed, and only simple cleaning is needed.

3. When some production personnel enter the operation of the product bottling tank, other workers also carry out subsequent operation on the finished product lead tank 5, the assembly line operation is basically realized, and the production efficiency is greatly improved.

4. In the production process, only the butt joint hole 11 at the bottom of the transfer hot chamber 1 is momentarily opened in the process of entering and exiting the lead can 5, and the diameter of the butt joint hole 11 is also very small, so that the possibility of leakage of radioactive aerosol is basically avoided, and the risk that production personnel are irradiated by the inside is reduced.

In this embodiment, the inner wall of the flared section 111 is provided with a sealing gasket. Therefore, after the lead can 5 is butted with the butt joint hole 11, the sealing performance between the top wall of the lead can 5 and the inner wall of the flared section 111 of the butt joint hole 11 is better, and the aerosol in the transfer hot chamber 1 is effectively prevented from leaking.

The embodiment also provides a conveying device 2, and the conveying device 2 is matched with the radioactive drug product bottled tank transferring system for use. The conveying device 2 comprises a plurality of carrying assemblies, a power assembly and a transmission assembly 6 in transmission connection with the power assembly. The carrying components are connected to the transmission component 6, so that the transmission component 6 drives the carrying components to move.

The transmission assembly 6 comprises a transmission chain 61 and a plurality of transmission gears 62. In practice, the number of the transmission gears 62 is 4, and the 4 transmission gears 62 are distributed in a ring shape. The transmission chain 61 is fitted to a plurality of transmission gears 62 and is arranged in a ring shape.

The carrier assembly includes a carrier frame 22 and a plurality of rollers 23 coupled to the carrier frame 22. The carrier 22 is connected to the driving chain 61 so that the carrier 22 can follow the driving chain 61. In practice, the carrier rack 22 may be hinged to a hinge point of the drive chain 61. The rollers 23 are used to support and facilitate movement of the carrier. The object carrier 22 is provided with an avoiding hole 221 matching with the lifting device 3, so that the lifting device 3 can pass through the avoiding hole 221. The carrier assembly further comprises a carrier tray 21 arranged to fit into the relief hole 221. The carrier tray 21 is placed in the escape hole 221 and supported by the carrier frame 22. In the ascending process of the lifting device 3, the lifting device 3 penetrates through the avoiding hole 221 and jacks up the carrying tray 21, and then jacks up the lead cans 5 placed on the carrying tray 21 to contact the transfer hot chamber 1. When the lifting device 3 is lifted, the lifting device 3 gradually exits the avoiding hole 221 and places the loading tray 21 in the avoiding hole 221 and is supported by the loading frame 22.

The conveying device 2 is matched with the lifting device 3 for use, and can be convenient for the lifting device 3 to lift the lead tank 5 to the abutting transfer hot chamber 1 or place the lead tank 5 on an object to be conveyed to the next station. In the process, the lifting of the lifting device 3 cannot interfere with the conveying device 2, so that the lead can 5 is conveniently put into the medicine bottle, and the transfer of the lead can 5 is also facilitated.

In this embodiment, the loading tray 21 is provided with a placing groove 211 in cooperation with the lead can 5, so that the lead can 5 can be accommodated in the placing groove 211. The placement groove 211 is sized to fit the bottom of the lead can 5 such that the lead can 5 can just fit into the placement groove 211. The depth of the placement groove 211 is set to about one third of the height of the lead can 5. After the lead can 5 is placed in the placing groove 211, the lead can 5 cannot be toppled.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A radiopharmaceutical product bottled tank transfer system is used in cooperation with a lead tank (5); the method is characterized in that: the radioactive drug product bottled tank transferring system comprises a transferring hot chamber (1), a conveying device (2), a lifting device (3) and a manipulator (4); the bottom of the transfer hot chamber (1) is provided with a butt joint hole (11) matched with the lead tank (5), so that the top end of the lead tank (5) can extend into the butt joint hole (11) and the top of the lead tank (5) is attached to the bottom of the transfer hot chamber (1);

the manipulator (4) is arranged inside the transfer hot chamber (1); the lifting device (3) is arranged right below the butt joint hole (11);

the conveying device (2) is matched with the lifting device (3) to be arranged, so that the conveying device (2) can convey the lead tank (5) to the position above the lifting device (3) or convey the lead tank (5) at the upper end of the lifting device (3) to the next station.

2. The radiopharmaceutical product vial transport system of claim 1, wherein: the top end of the lead tank (5) is arranged in a round table shape; the lower end of the butt joint hole (11) is matched with the top end of the lead can (5) and is provided with a flaring section (111), so that the top wall of the lead can (5) can be attached to the inner wall of the flaring section (111).

3. The radiopharmaceutical product vial transport system of claim 2, wherein: and a sealing gasket is arranged on the inner wall of the flaring section (111).

4. The radiopharmaceutical product vial transport system of claim 1, wherein: the manipulator (4) comprises a lead plug (51) taking and placing assembly and a medicine bottle taking and placing assembly; the lead plug (51) taking and placing assembly comprises a lifting cylinder (41) vertically arranged right above the butt joint hole (11) and a clamping cylinder connected to the lower end of the lifting cylinder (41).

5. A kind of conveying appliance, its characteristic is: the delivery device (2) is used in conjunction with a radiopharmaceutical product bottled tank transfer system of any one of claims 1 to 4; the conveying device (2) comprises a plurality of carrying assemblies, a power assembly and a transmission assembly (6) in transmission connection with the power assembly; the plurality of carrying assemblies are connected to the transmission assembly (6) so that the transmission assembly (6) drives the plurality of carrying assemblies to move;

the carrying component is provided with an avoiding hole (221) in cooperation with the lifting device (3) so that the lifting device (3) can penetrate through the avoiding hole (221); the object carrying assembly is further matched with the avoiding hole (221) and provided with an object carrying tray (21), so that the object carrying tray (21) can be placed in the avoiding hole (221).

6. The delivery device of claim 5, wherein: the transmission assembly (6) comprises a transmission chain (61) and a plurality of transmission gears (62); the transmission chain (61) is matched with the transmission gears (62) and is arranged in an annular shape;

the carrying assembly comprises a carrying rack (22) and a plurality of rollers (23) connected with the carrying rack (22); the avoidance hole (221) is arranged on the object carrier (22).

7. The delivery device of claim 5, wherein: the carrying tray (21) is provided with a placing groove (211) matched with the lead tank (5) so that the lead tank (5) can be contained in the placing groove (211).