CN212871934U - Porous plate filtering device - Google Patents
Porous plate filtering device Download PDFInfo
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- CN212871934U CN212871934U CN202022231790.8U CN202022231790U CN212871934U CN 212871934 U CN212871934 U CN 212871934U CN 202022231790 U CN202022231790 U CN 202022231790U CN 212871934 U CN212871934 U CN 212871934U
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Abstract
The utility model provides a porous plate filtering device, which comprises a porous plate, a clamping jaw, a moving assembly, a guide block, a blowing positive pressing block and a frame; the movable assembly, the guide block and the air blowing positive pressing block are all arranged on the rack, the clamping jaw is connected with the movable assembly and can move under the action of the movable assembly, the clamping jaw can grab the porous plate, the porous plate is arranged on the guide block, and the guide block is positioned below the air blowing positive pressing block; the perforated plate comprises a hole lattice, a filter membrane and a filter liquid disc, the filter membrane is connected to the bottom of the hole lattice, the filter liquid disc is detachably connected below the filter membrane, and the edges of two sides of the perforated plate are turned outwards to form a clamping position. The utility model has the advantages of simple and reasonable structure, can filter a plurality of samples simultaneously through adopting the perforated plate, be applicable to batch sample preparation. The utility model discloses a positive briquetting of blowing realizes filtering with the filter membrane cooperation, replaces traditional centrifugal filtration, labour saving and time saving.
Description
Technical Field
The utility model relates to the technical field of medical appliances, in particular to a porous plate filtering device.
Background
When analyzing cells, cell nuclei or other organelles, a sample is filtered to remove large-particle impurities, so as to obtain a filtrate containing target cells, cell nuclei or organelles, and the filtrate is usually centrifuged to collect the target cells, cell nuclei or organelles. At present, a sample filter chamber is usually to filter a sample into a container first, and then transfer filtrate in the container into a centrifuge tube, which is complex in process and easy to cause bacterial contamination.
Patent document with publication number CN209226978U discloses a placenta tissue stem cell filtering device, which comprises a stem cell filtering member, a tissue fluid accommodating chamber, a tissue fluid recovery chamber and a mounting bracket, wherein the mounting bracket is provided with a base and a height adjusting mechanism, the tissue fluid accommodating chamber is arranged at the upper part of the mounting bracket through the height adjusting mechanism, the stem cell filtering member is arranged below the tissue fluid accommodating chamber, the stem cell filtering member is communicated to the tissue fluid recovery chamber through a drainage tube, and the tissue fluid recovery chamber is arranged on the base; the stem cell filter element comprises a stem cell filter element upper opening, a filter membrane carrying platform and a stem cell filter element lower opening, and the filter membrane is arranged on the filter membrane carrying platform; the stem cell filtering piece is provided with a rubber cap at the lower opening, the upper opening of the stem cell filtering piece is connected with the tissue fluid containing cavity, and the lower opening of the stem cell filtering piece is communicated with the tissue fluid recovery cavity through a drainage tube. The technical solution in this patent document can only achieve the preparation of one sample at a time, and is not suitable for batch sample preparation.
SUMMERY OF THE UTILITY MODEL
To the defects in the prior art, the utility model aims at providing a perforated plate filter equipment.
According to the utility model, the perforated plate filtering device comprises a perforated plate, a clamping jaw, a moving assembly, a guide block, a blowing positive pressing block and a frame;
remove subassembly, guide block, the positive briquetting of blowing all sets up in the frame, and the clamping jaw is connected and is removed the subassembly and can move under the effect of removing the subassembly, and the clamping jaw can snatch the perforated plate, and the perforated plate is installed on the guide block, and the guide block is located the below of the positive briquetting of blowing.
Preferably, the moving assembly comprises an X-axis slide rail and a Y-axis slide rail, the Y-axis slide rail is mounted on the X-axis slide rail and can move on the X-axis slide rail, and the clamping jaw is mounted on the Y-axis slide rail and can move on the Y-axis slide rail.
Preferably, the guide block is movably connected with the rack, and the guide block can translate and rotate below the air-blowing positive pressure block.
Preferably, the air blowing positive pressure block is movably connected with the rack, and the air blowing positive pressure block can translate and/or rotate above the guide block;
the positive blowing pressure block can be connected with external gas through a pipeline.
Preferably, the perforated plate comprises a cell, a filter membrane and a filtrate disc, wherein the filter membrane is connected to the bottom of the cell, the filtrate disc is detachably connected below the filter membrane, and the edges of two sides of the perforated plate are turned outwards to form a clamping position.
Preferably, one or more clamping strips are arranged at the bottom of the edge of the porous plate, one or more clamping grooves are formed in the clamping jaw, and when the clamping jaw is clamped at the clamping position of the porous plate, the clamping strips and the clamping grooves are correspondingly connected in a matched mode one by one;
and a corner cut is arranged on the edge of one side of the porous plate to form a placement mark.
Preferably, the number of the cells is multiple, and the multiple cells are arranged in multiple rows and multiple columns; the hole lattice is in the shape of a door arch, T or triangle.
Preferably, the diameter of the filter membrane filtration pore is 5-50 microns.
Preferably, the stacking device further comprises a stacking assembly, wherein the stacking assembly comprises a plurality of layers of placing positions, and the placing positions can place the porous plates.
According to the utility model, the perforated plate filtering device comprises a perforated plate, a clamping jaw, a moving assembly, a guide block, a blowing positive pressing block and a frame;
the movable assembly, the guide block and the air blowing positive pressing block are all arranged on the rack, the clamping jaw is connected with the movable assembly and can move under the action of the movable assembly, the clamping jaw can grab the porous plate, the porous plate is arranged on the guide block, and the guide block is positioned below the air blowing positive pressing block;
the moving assembly comprises an X-axis sliding rail and a Y-axis sliding rail, the Y-axis sliding rail is mounted on the X-axis sliding rail and can move on the X-axis sliding rail, and the clamping jaw is mounted on the Y-axis sliding rail and can move on the Y-axis sliding rail;
the guide block is movably connected with the rack and can translate and rotate below the air blowing positive pressure block;
the air blowing positive pressure block is movably connected with the rack, and the air blowing positive pressure block can translate and/or rotate above the guide block;
the positive blowing pressure block can be connected with external gas through a pipeline;
the multi-hole plate comprises holes, filter membranes and a filtrate disc, the filter membranes are connected to the bottoms of the holes, the filtrate disc is detachably connected below the filter membranes, and the edges of the two sides of the multi-hole plate are turned outwards to form a clamping position;
one or more clamping strips are arranged at the bottom of the edge of the porous plate, one or more clamping grooves are formed in the clamping jaw, and when the clamping jaw is clamped at the clamping position of the porous plate, the clamping strips are correspondingly connected with the clamping grooves in a matched mode;
a corner cut is arranged on the edge of one side of the porous plate to form a placement mark;
the number of the holes is multiple, and the holes are arranged in multiple rows and multiple columns; the hole grids are in door arch shapes, T shapes or triangular shapes;
the diameter of the filter membrane filter hole is 5-50 microns;
still include stack assembly, stack assembly includes the multilayer and places the position, place the position and can place the perforated plate.
Compared with the prior art, the utility model discloses following beneficial effect has:
1. the utility model has the advantages of simple and reasonable structure, can filter a plurality of samples simultaneously through adopting the perforated plate, be applicable to batch sample preparation.
2. The utility model discloses a positive briquetting of blowing realizes filtering with the filter membrane cooperation, replaces traditional centrifugal filtration, labour saving and time saving.
3. The utility model discloses perforated plate bottom can be dismantled and connect the filtrating dish, and the convenience is collected and is emptyd filtrating.
4. The utility model discloses set up the card strip bottom perforated plate border, set up the draw-in groove simultaneously on the clamping jaw, during clamping jaw centre gripping perforated plate, card strip and draw-in groove accordant connection can prevent to snatch and remove the relative clamping jaw of in-process perforated plate and slide.
5. The utility model discloses set up the corner cut formation on perforated plate one side border and place the sign, prevent that the perforated plate from putting in the storehouse subassembly and turning over, influencing subsequent operation.
Drawings
Other features, objects and advantages of the invention will become more apparent upon reading of the detailed description of non-limiting embodiments with reference to the following drawings:
fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic perspective view of the porous plate of the present invention.
Fig. 3 is a schematic view of the perforated plate of the present invention.
Fig. 4 is a schematic view of the clamping jaw clamping the perforated plate of the present invention.
The figures show that:
perforated plate 1301Y-axis slide rail 1306
Jaw 1302 frame 1307
Blowing positive pressure block 1304 clamping strip 1309
Detailed Description
The present invention will be described in detail with reference to the following embodiments. The following examples will assist those skilled in the art in further understanding the present invention, but are not intended to limit the invention in any way. It should be noted that various changes and modifications can be made by one skilled in the art without departing from the spirit of the invention. These all belong to the protection scope of the present invention.
In the description of the present application, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience in describing the present application and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present application.
According to the utility model, as shown in figure 1, the perforated plate filtering device comprises a perforated plate, a clamping jaw, a moving assembly, a guide block, a blowing positive pressure block and a frame; remove subassembly, guide block, the positive briquetting of blowing all sets up in the frame, and the clamping jaw is connected and is removed the subassembly and can move under the effect of removing the subassembly, and the clamping jaw can snatch the perforated plate, and the perforated plate is installed on the guide block, and the guide block is located the below of the positive briquetting of blowing. The movable assembly comprises an X-axis slide rail and a Y-axis slide rail, the Y-axis slide rail is installed on the X-axis slide rail and can move on the X-axis slide rail, and the clamping jaw is installed on the Y-axis slide rail and can move on the Y-axis slide rail. Still include stack assembly, stack assembly includes the multilayer and places the position, place the position and can place the perforated plate.
The guide block is movably connected with the rack, and the guide block can translate and rotate below the air blowing positive pressure block. The air blowing positive pressure block is movably connected with the rack, and the air blowing positive pressure block can translate and/or rotate above the guide block; the positive blowing pressure block can be connected with external gas through a pipeline.
As shown in fig. 2-4, the multi-well plate comprises a cell, a filter membrane and a filtrate disc, wherein the filter membrane is connected to the bottom of the cell, the filtrate disc is detachably connected below the filter membrane, and the two side edges of the multi-well plate are turned outwards to form a clamping position. One or more clamping strips are arranged at the bottom of the edge of the porous plate, one or more clamping grooves are formed in the clamping jaw, and when the clamping jaw is clamped at the clamping position of the porous plate, the clamping strips are correspondingly connected with the clamping grooves in a matched mode; and a corner cut is arranged on the edge of one side of the porous plate to form a placement mark. The number of the holes is multiple, and the holes are arranged in multiple rows and multiple columns; the hole lattice is in the shape of a door arch, T or triangle. The diameter of the filter membrane filter hole is 5-50 microns.
Preferably, the porous plate comprises 24 door arch-shaped grids which are arranged in 6 rows and 4 columns, the filter membrane adopts a screen, the screen is welded at the bottom of the grid through a hot welding process, the diameter of the arc part of the door arch-shaped grid is phi 4-50 mm, the width of the straight line side of the door arch-shaped grid is 4-50 mm, the depth of the door arch-shaped grid is 5-40 mm, the liquid filling amount of the porous plate is 20-3000 microliter, and the material of the porous plate is PES (polyether sulfone resin), PE (polyethylene) or PET (polyethylene terephthalate).
Utilize the utility model provides a perforated plate filter equipment to carry out filtering method, include following step:
the method comprises the following steps: placing a perforated plate into the stack assembly;
step two: the clamping jaw moves to the stack assembly through the moving assembly and clamps the clamping position of the porous plate, then moves to the guide block through the moving assembly, and installs the porous plate on the guide block; preferably, the clamping jaw moves into the stack assembly through the X-axis sliding rail to grab the porous plates, each layer of porous plate in the stack assembly is grabbed through the movement of the Y-axis sliding rail, and the porous plates are sequentially grabbed from top to bottom and placed on the guide block through the movement of the X-axis sliding rail;
step three: the guide block moves to enable one side of the porous plate to incline upwards; preferably, when the hole grid is in the shape of a door arch, the placing mark is arranged on the opposite side of the arc shape of the door arch, the placing mark is positioned on the inner side of the stack assembly when placed, the clamping jaw takes the counter-hole plate out of the stack assembly and places the counter-hole plate on the guide block, the guide block moves, one end, provided with the placing mark, of the porous plate is inclined upwards, the arc-shaped end of the door arch is positioned at the lowest point, the linear end of the door arch is positioned at the highest point, namely the lowest point of the hole grid has a converging effect, and filtered substances are gathered at the lowest point after filtration; when the hole lattice is T-shaped, the porous plate is inclined to enable the bottom end of the T-shaped vertical arm to be located at the lowest point, and the T-shaped cross arm is located at the highest point; when the hole lattice is triangular, the hole plate is inclined so that the vertex of the triangle is positioned at the lowest point, and the side of the triangle is positioned at the highest point; preferably, the perforated plate is inclined upward at an angle of 5 to 30 °;
step four: dropping the sample into the cells of the porous plate through an external sample adding device; preferably, the samples are sequentially loaded in a single row, the samples are loaded at the highest point of each inclined cell, and the samples are loaded by the sample loading device through TIP heads;
step five: and starting the air blowing positive pressing block to blow air to the porous plate for applying pressure for filtering, and moving the air blowing positive pressing block or the guide block to perform single-row successive filtering on the cells on the porous plate. The filtered sample is taken out at the lowest point of the inclined cell by a sampling device, which preferably takes a sample with a TIP head, into the next process.
In one embodiment, the utility model discloses be applied to and separate out the cell in cell preservation liquid or the cell stoste, filter the liquid through the filter membrane, remain required cell, filter cell impurity can make the cell morphology preserve well. The utility model discloses can be applied to TCT inspection (liquid-based thin layer cell detection). The clamping jaw moves through the Y-axis slide rail to sequentially grab the eight porous plates placed in the stack assembly from top to bottom; the gripping jaws move the gripped porous plates through the X-axis slide rail to place the porous plates into the guide blocks for fixation; after the porous plate is fixed, the TIP head sucks cell stock solution from the sample cup and places the cell stock solution into a cell in the porous plate; the air blowing positive pressing block moves downwards to the position of the porous plate through the guide rail, the air blowing positive pressing block performs air blowing pressure application filtration, the porous plates are pushed forwards one grid in one row after each filtration is finished, and the next porous plate is replaced until all the 4 rows and 6 rows of the porous plates are used up.
The foregoing description of the specific embodiments of the invention has been presented. It is to be understood that the present invention is not limited to the specific embodiments described above, and that various changes or modifications may be made by those skilled in the art within the scope of the appended claims without departing from the spirit of the invention. The embodiments and features of the embodiments of the present application may be combined with each other arbitrarily without conflict.
Claims (10)
1. A porous plate filtering device is characterized by comprising a porous plate, a clamping jaw, a moving assembly, a guide block, a blowing positive pressing block and a rack;
remove subassembly, guide block, the positive briquetting of blowing all sets up in the frame, and the clamping jaw is connected and is removed the subassembly and can move under the effect of removing the subassembly, and the clamping jaw can snatch the perforated plate, and the perforated plate is installed on the guide block, and the guide block is located the below of the positive briquetting of blowing.
2. The multi-well plate filtration device according to claim 1, wherein said moving assembly comprises an X-axis slide rail, a Y-axis slide rail mounted on and movable on the X-axis slide rail, and a clamping jaw mounted on and movable on the Y-axis slide rail.
3. A multi-well plate filter device as recited in claim 1, wherein the guide block is movably connected to the frame, the guide block being capable of translating and rotating below the air-blowing positive pressure block.
4. The multi-plate filter device according to claim 1, wherein the air-blowing positive pressure block is movably connected with the frame, and the air-blowing positive pressure block can translate and/or rotate above the guide block;
the positive blowing pressure block can be connected with external gas through a pipeline.
5. A multi-well plate filtration unit according to claim 1 wherein said multi-well plate comprises wells, filter membranes attached to the bottom of the wells, and filtrate trays removably attached below the filter membranes, the multi-well plate being turned inside out on both sides to form a clamping position.
6. The multi-well plate filtering device according to claim 5, wherein one or more clamping strips are arranged at the bottom of the edge of the multi-well plate, one or more clamping grooves are arranged on the clamping jaw, and when the clamping jaw is clamped at the clamping position of the multi-well plate, the clamping strips are correspondingly matched and connected with the clamping grooves one by one;
and a corner cut is arranged on the edge of one side of the porous plate to form a placement mark.
7. A multi-well plate filtration unit according to claim 5, wherein said cells are plural, and a plurality of cells are arranged in a plurality of rows and columns; the hole lattice is in the shape of a door arch, T or triangle.
8. A multi-well plate filtration apparatus according to claim 5, wherein said filter membrane has filtration pores of 5 to 50 μm in diameter.
9. The multiwell plate filtration device of claim 1, further comprising a stack assembly comprising a multi-layer placement location capable of placing multiwell plates.
10. A porous plate filtering device is characterized by comprising a porous plate, a clamping jaw, a moving assembly, a guide block, a blowing positive pressing block and a rack;
the movable assembly, the guide block and the air blowing positive pressing block are all arranged on the rack, the clamping jaw is connected with the movable assembly and can move under the action of the movable assembly, the clamping jaw can grab the porous plate, the porous plate is arranged on the guide block, and the guide block is positioned below the air blowing positive pressing block;
the moving assembly comprises an X-axis sliding rail and a Y-axis sliding rail, the Y-axis sliding rail is mounted on the X-axis sliding rail and can move on the X-axis sliding rail, and the clamping jaw is mounted on the Y-axis sliding rail and can move on the Y-axis sliding rail;
the guide block is movably connected with the rack and can translate and rotate below the air blowing positive pressure block;
the air blowing positive pressure block is movably connected with the rack, and the air blowing positive pressure block can translate and/or rotate above the guide block;
the positive blowing pressure block can be connected with external gas through a pipeline;
the multi-hole plate comprises holes, filter membranes and a filtrate disc, the filter membranes are connected to the bottoms of the holes, the filtrate disc is detachably connected below the filter membranes, and the edges of the two sides of the multi-hole plate are turned outwards to form a clamping position;
one or more clamping strips are arranged at the bottom of the edge of the porous plate, one or more clamping grooves are formed in the clamping jaw, and when the clamping jaw is clamped at the clamping position of the porous plate, the clamping strips are correspondingly connected with the clamping grooves in a matched mode;
a corner cut is arranged on the edge of one side of the porous plate to form a placement mark;
the number of the holes is multiple, and the holes are arranged in multiple rows and multiple columns; the hole grids are in door arch shapes, T shapes or triangular shapes;
the diameter of the filter membrane filter hole is 5-50 microns;
still include stack assembly, stack assembly includes the multilayer and places the position, place the position and can place the perforated plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022231790.8U CN212871934U (en) | 2020-10-09 | 2020-10-09 | Porous plate filtering device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022231790.8U CN212871934U (en) | 2020-10-09 | 2020-10-09 | Porous plate filtering device |
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| Publication Number | Publication Date |
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| CN212871934U true CN212871934U (en) | 2021-04-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202022231790.8U Active CN212871934U (en) | 2020-10-09 | 2020-10-09 | Porous plate filtering device |
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| CN (1) | CN212871934U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112067412A (en) * | 2020-10-09 | 2020-12-11 | 嘉兴晶铸生物科技有限公司 | Multi-well plate filtration device and method |
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2020
- 2020-10-09 CN CN202022231790.8U patent/CN212871934U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112067412A (en) * | 2020-10-09 | 2020-12-11 | 嘉兴晶铸生物科技有限公司 | Multi-well plate filtration device and method |
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