CN212830219U - Glycocholic acid determination kit - Google Patents
Glycocholic acid determination kit Download PDFInfo
- Publication number
- CN212830219U CN212830219U CN202021314211.XU CN202021314211U CN212830219U CN 212830219 U CN212830219 U CN 212830219U CN 202021314211 U CN202021314211 U CN 202021314211U CN 212830219 U CN212830219 U CN 212830219U
- Authority
- CN
- China
- Prior art keywords
- groove
- kit
- reagent
- kit body
- glycocholic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- RFDAIACWWDREDC-FRVQLJSFSA-N glycocholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 RFDAIACWWDREDC-FRVQLJSFSA-N 0.000 title claims abstract description 36
- 108010007979 Glycocholic Acid Proteins 0.000 title claims abstract description 34
- RFDAIACWWDREDC-UHFFFAOYSA-N Na salt-Glycocholic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(=O)NCC(O)=O)C)C1(C)C(O)C2 RFDAIACWWDREDC-UHFFFAOYSA-N 0.000 title claims abstract description 34
- 229940099347 glycocholic acid Drugs 0.000 title claims abstract description 34
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 50
- 239000012445 acidic reagent Substances 0.000 claims abstract description 16
- 238000005057 refrigeration Methods 0.000 claims description 13
- 238000003149 assay kit Methods 0.000 claims description 7
- 238000004321 preservation Methods 0.000 claims description 5
- 229920000742 Cotton Polymers 0.000 claims description 4
- 238000013016 damping Methods 0.000 claims 1
- 238000012864 cross contamination Methods 0.000 abstract description 7
- 230000006870 function Effects 0.000 description 4
- 208000006454 hepatitis Diseases 0.000 description 4
- 210000002966 serum Anatomy 0.000 description 4
- 210000005229 liver cell Anatomy 0.000 description 3
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 description 2
- 206010008909 Chronic Hepatitis Diseases 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- 231100000354 acute hepatitis Toxicity 0.000 description 2
- 239000003613 bile acid Substances 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 235000019416 cholic acid Nutrition 0.000 description 2
- 208000019425 cirrhosis of liver Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 201000007270 liver cancer Diseases 0.000 description 2
- 208000014018 liver neoplasm Diseases 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- BHQCQFFYRZLCQQ-UHFFFAOYSA-N (3alpha,5alpha,7alpha,12alpha)-3,7,12-trihydroxy-cholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 BHQCQFFYRZLCQQ-UHFFFAOYSA-N 0.000 description 1
- 239000004380 Cholic acid Substances 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- -1 and in hepatocytes Chemical compound 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- BHQCQFFYRZLCQQ-OELDTZBJSA-N cholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 BHQCQFFYRZLCQQ-OELDTZBJSA-N 0.000 description 1
- 229960002471 cholic acid Drugs 0.000 description 1
- 239000002812 cholic acid derivative Substances 0.000 description 1
- 150000001842 cholic acids Chemical class 0.000 description 1
- KXGVEGMKQFWNSR-UHFFFAOYSA-N deoxycholic acid Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 KXGVEGMKQFWNSR-UHFFFAOYSA-N 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 210000003494 hepatocyte Anatomy 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 238000007449 liver function test Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses a glycocholic acid determination kit in the technical field of determination kits, which comprises a kit body, wherein a box cover is arranged on the kit body, a handle and a buckle are arranged on the box cover, a clamping groove matched with the buckle is arranged on the kit body, a marking groove is arranged on the front surface of the kit body, a drawer is arranged at the bottom of the marking groove, a control panel is arranged on one side wall of the kit body, a display screen is arranged on the control panel, a drawer button and a temperature adjusting switch are arranged at the bottom of the display screen, a plurality of debugging reagent grooves are arranged in a cavity of the kit body, a plurality of glycocholic acid reagent grooves are arranged at one side of the debugging reagent grooves, a cover plate is arranged on the glycocholic acid reagent grooves, one end of the cover plate is movably connected with the kit body through a, the reagents are placed in order and classified, so that confusion and reagent volatilization cross contamination are prevented, and the working efficiency is improved.
Description
Technical Field
The utility model relates to a detect reagent box technical field, specifically be a glycocholic acid detect reagent box.
Background
Serum glycocholic acid (CG) is one of the conjugated cholic acids formed by the combination of cholic acid and glycine, and in hepatocytes, cholesterol is converted into primary bile acid through its complex enzymatic reaction. In normal cases, there are very low levels of CG in the peripheral blood. When the liver cells are damaged, the CG uptake capacity of the liver cells is reduced, so that the content of CG in blood is increased; when bile stagnates, bile acid excretion by the liver becomes obstructed, and the content of CG in the blood circulation of the regurgitation increases, which also increases the content of CG in serum. A large number of researches show that CG has greater advantages compared with the traditional liver function test index as a clinical index for detecting liver diseases. The serum glycocholic acid level of patients with chronic hepatitis, acute hepatitis, liver cirrhosis and liver cancer is obviously higher than that of a control group, and the CG level is gradually increased along with the increase of the severity of liver lesion (chronic hepatitis < acute hepatitis < liver cirrhosis < liver cancer). Therefore, the determination of serum glycocholic acid (CG) is one of the sensitive indicators for evaluating the function of liver cells and the circulating function of the substance in the hepatobiliary system.
Most glycocholic acid assay kits in the conventional technology are paper kits, the protective effect on reagents is weak, some kits are easy to be confused and cross-polluted due to concentrated placement of the reagents, and in use, the reagents are inconvenient to find, the work efficiency is influenced, some tools and droppers are not specially placed, the droppers are easy to be polluted, the requirements of the reagents on temperature are harsh, and some kits are not provided with a refrigerating device, so that the quality of the reagents is influenced.
Based on this, the utility model designs a glycocholic acid assay kit to solve above-mentioned problem.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a glycocholic acid assay kit to solve the glycocholic acid assay kit that proposes in the above-mentioned background art and mostly be the paper kit, protective action to reagent is less strong, some kits, reagent is concentrated and is placed easy confusion, easy cross contamination, and during the use, it is inconvenient to look for, influence work efficiency, some instruments and burette do not have special position of placing, the burette easily pollutes, and reagent also is more harsh to the temperature requirement, some kits do not have refrigerating plant, influence reagent quality problem.
In order to achieve the above object, the utility model provides a following technical scheme: a glycocholic acid determination kit comprises a kit body, wherein a box cover is arranged on the kit body, a handle and a buckle are arranged on the box cover, a clamping groove matched with the buckle is arranged on the kit body, a marking groove is arranged on the front side of the kit body, a drawer is arranged at the bottom of the marking groove, a control panel is arranged on one side wall of the kit body, a display screen is arranged on the control panel, a drawer button and a temperature adjusting switch are arranged at the bottom of the display screen, a plurality of debugging reagent grooves are arranged in a cavity of the kit body, a baffle is arranged at one side of the debugging reagent grooves, a plurality of glycocholic acid reagent grooves are arranged at one side of the baffle, a cover plate is arranged on the glycocholic acid reagent grooves, one end of the cover plate is movably connected with the kit body through a rotating shaft, and, prevent confusion and difficult finding and reagent volatilization cross contamination, improve work efficiency.
As the utility model discloses a further scheme, be provided with burette groove and tool holder in the cavity of drawer, a plurality of droppers have been placed on the burette groove, the one end in burette groove is provided with burette head protection groove, be provided with the elasticity tape on the burette groove, test tube and instrument have the position of placing, prevent to pollute.
As a further scheme of the utility model, be provided with the cotton layer of heat preservation between debugging reagent groove and the glycocholic acid reagent groove, the box cover is provided with a plurality of debugging reagent lids, improves the heat preservation effect, has prevented reagent cross contamination.
As a further scheme of the utility model, the bottom of kit body is provided with the buffer layer, be provided with the battery jar on the lateral wall of kit body, be provided with the battery on the battery jar, the top of battery jar is provided with the refrigeration generator, the top of refrigeration generator is provided with temperature sensor, control panel, display screen, refrigeration generator all with battery electric connection, prevent the vibrations that the kit produced in the transportation, prevent that reagent from colliding, have the refrigeration function to the kit, guarantee reagent temperature requirement improves the reagent quality, practices thrift the cost.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the utility model prevents the reagent from being disordered and cross contamination by arranging a plurality of debugging reagent grooves and glycocholic acid reagent grooves, is convenient for people to select, saves the time and cost, and improves the working efficiency;
2. the utility model can refrigerate the reagent box by arranging the refrigerator, provide the temperature required by the reagent and improve the quality of the reagent;
3. the utility model discloses a set up burette groove and instrument groove, can make things convenient for burette and other instruments to place, prevent burette and instrument pollution.
4. The utility model discloses a set up control panel and display screen and can conveniently regulate and control the temperature, considerable with the temperature.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic view of the inside of the present invention;
FIG. 3 is a drawing showing the combination of a dropper groove and a dropper according to the present invention;
fig. 4 is an enlarged view of the position a of the present invention.
In the drawings, the components represented by the respective reference numerals are listed below:
1. a kit body; 2. a box cover; 3. a handle; 4. buckling; 5. a card slot; 6. marking a slot; 7. a drawer; 8. a control panel; 9. a display screen; 10. a drawer button; 11. a temperature regulating switch; 12. debugging a reagent tank; 13. a glycocholic acid reagent tank; 14. a cover plate; 15. a dropper slot; 16. a tool slot; 17. a dropper; 18. a dropper head protection groove; 19. tightening or loosening the belt; 20. A heat insulation cotton layer; 21. debugging a reagent cover; 22. a shock-absorbing layer; 23. a battery cell; 24. a storage battery; 25. a refrigeration generator; 26. a temperature sensor; 27. and a baffle plate.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.
Referring to fig. 1-4, the present invention provides a technical solution: a glycocholic acid determination kit comprises a kit body 1, wherein a kit cover 2 is arranged on the kit body 1, a handle 3 and a buckle 4 are arranged on the kit cover 2, a clamping groove 5 matched with the buckle 4 is arranged on the kit body 1, a marking groove 6 is arranged on the front surface of the kit body 1, a drawer 7 is arranged at the bottom of the marking groove 6, a control panel 8 is arranged on one side wall of the kit body 1, a display screen 9 is arranged on the control panel 8, a drawer button 10 and a temperature adjusting switch 11 are arranged at the bottom of the display screen 9, a plurality of debugging reagent grooves 12 are arranged in a cavity of the kit body 1, a baffle 27 is arranged at one side of the debugging reagent grooves 12, a plurality of glycocholic acid reagent grooves 13 are arranged at one side of the baffle 27, and a cover plate 14 is arranged on the glycocholic acid reagent grooves 13, one end of the cover plate 14 is movably connected with the kit body 1 through a rotating shaft, and the reagents are placed in an orderly and classified mode, so that confusion, difficulty in finding and reagent volatilization cross contamination are prevented, and the working efficiency is improved.
A dropper groove 15 and a tool groove 16 are arranged in a cavity of the drawer 7, a plurality of droppers 17 are placed on the dropper groove 15, a dropper head protection groove 18 is arranged at one end of the dropper groove 15, an elastic tape 19 is arranged on the dropper groove 15, and test tubes and tools are placed in positions to prevent pollution.
Be provided with the cotton layer 20 of heat preservation between debugging reagent groove 12 and glycocholic acid reagent groove 13, be provided with a plurality of debugging reagent lids 21 on the lid 2, improve the heat preservation effect, prevented reagent cross contamination.
The bottom of kit body 1 is provided with buffer layer 22, be provided with battery jar 23 on the lateral wall of kit body 1, be provided with battery 24 on the battery jar 23, the top of battery jar 23 is provided with refrigeration generator 25, refrigeration generator 25's top is provided with temperature sensor 26, control panel 8, display screen 9, refrigeration generator 25 all with battery 24 electric connection, prevent the vibrations that the kit produced in the transportation, prevent that reagent from colliding, have the refrigeration function to the kit, guarantee reagent temperature requirement, improve reagent quality, practice thrift the cost.
The working principle is as follows: when the glycocholic acid determination kit works, firstly, a worker opens a temperature adjusting button switch 11 to adjust the temperature required by a reagent, a refrigeration generator 25 refrigerates, the display screen 9 displays the temperature sensed by a temperature sensor 26 on the display screen 9, a debugging reagent is placed in a debugging reagent groove 12, a drawer 7 is opened through a drawer button 10, a dropper 17 and a tool are taken out, the glycocholic acid reagent can be debugged on a cover plate 14, the debugged glycocholic acid reagent is placed in a glycocholic acid reagent groove 13, the cover plate 14 is covered, the dropper 17 and the tool are respectively placed in a dropper groove 15 and a tool groove 16, the drawer 7 is closed, the box cover 2 is covered, and the debugging reagent cover 21 seals the debugging reagent groove 12.
In the description herein, references to the description of "one embodiment," "an example," "a specific example," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and its practical applications, to thereby enable others skilled in the art to best understand the invention for and utilize the invention. The present invention is limited only by the claims and their full scope and equivalents.
Claims (4)
1. A glycocholic acid determination kit comprises a kit body (1), wherein a kit cover (2) is arranged on the kit body (1), a handle (3) and a buckle (4) are arranged on the kit cover (2), a clamping groove (5) matched with the buckle (4) is arranged on the kit body (1), an identification groove (6) is arranged on the front surface of the kit body (1), a drawer (7) is arranged at the bottom of the identification groove (6), a control panel (8) is arranged on one side wall of the kit body (1), a display screen (9) is arranged on the control panel (8), a drawer button (10) and a temperature adjusting switch (11) are arranged at the bottom of the display screen (9), a plurality of debugging reagent grooves (12) are arranged in a cavity of the kit body (1), a baffle plate (27) is arranged on one side of the debugging reagent grooves (12), one side of baffle (27) is provided with a plurality of glycocholic acid reagent groove (13), and is a plurality of be provided with apron (14) on glycocholic acid reagent groove (13), the one end of apron (14) with kit body (1) is through pivot swing joint.
2. The glycocholic acid assay kit according to claim 1, characterized in that: a dropper groove (15) and a tool groove (16) are arranged in a cavity of the drawer (7), a plurality of droppers (17) are placed on the dropper groove (15), a dropper head protection groove (18) is arranged at one end of the dropper groove (15), and an elastic tape (19) is arranged on the dropper groove (15).
3. The glycocholic acid assay kit according to claim 1, characterized in that: be provided with heat preservation cotton layer (20) between debugging reagent groove (12) and glycocholic acid reagent groove (13), be provided with a plurality of debugging reagent covers (21) on lid (2).
4. The glycocholic acid assay kit according to claim 1, characterized in that: the kit comprises a kit body (1) and is characterized in that a damping layer (22) is arranged at the bottom of the kit body (1), a storage battery groove (23) is formed in one side wall of the kit body (1), a storage battery (24) is arranged on the storage battery groove (23), a refrigeration generator (25) is arranged at the top end of the storage battery groove (23), a temperature sensor (26) is arranged at the top end of the refrigeration generator (25), and the control panel (8), the display screen (9) and the refrigeration generator (25) are all electrically connected with the storage battery (24).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021314211.XU CN212830219U (en) | 2020-07-07 | 2020-07-07 | Glycocholic acid determination kit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021314211.XU CN212830219U (en) | 2020-07-07 | 2020-07-07 | Glycocholic acid determination kit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN212830219U true CN212830219U (en) | 2021-03-30 |
Family
ID=75182648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021314211.XU Expired - Fee Related CN212830219U (en) | 2020-07-07 | 2020-07-07 | Glycocholic acid determination kit |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN212830219U (en) |
-
2020
- 2020-07-07 CN CN202021314211.XU patent/CN212830219U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210330 |