CN213229789U - Bacterial endotoxin detection kit - Google Patents

Abstract

The utility model discloses a bacterial endotoxin detect reagent box, wherein, this bacterial endotoxin detect reagent box's box body and lid pass through the magnetic part lid tightly, conveniently open and close with the lid, be provided with the fixed plate in the box body, be fixed with reagent and the consumptive material that are used for bacterial endotoxin detection experiment to be relevant on the fixed plate, through using this kit, need not prepare relevant reagent consumptive material alone before carrying out bacterial endotoxin detection experiment, reduce the preliminary work of preparing in earlier stage, make the experiment operation, the reagent consumptive material is preserved, it is more convenient to carry, and avoid different reagent producers, the different wholesale numbers of same reagent cause the influence to the testing result.

Description

Bacterial endotoxin detection kit

Technical Field

The utility model relates to the field of biotechnology, in particular to bacterial endotoxin detect reagent box.

Background

Endotoxin is a generic term for toxic substances present in the body of gram-negative bacteria (G-), a component of the cell wall of the bacteria, which releases toxins after lysis of the body, also known as "pyrogens". Endotoxin is located in the outermost layer of the cell wall, covering the mucin of the cell wall. The toxic action of endotoxin of various bacteria is weak, but human body is sensitive to the endotoxin of bacteria, and the endotoxin can cause various body reactions in vivo, such as fever, microcirculation disturbance, endotoxin shock, disseminated intravascular coagulation and the like.

At present, the method for detecting the level of bacterial endotoxin, which is commonly used in the clinical and biological research fields, mainly utilizes the fact that bacterial endotoxin forms gel on the tube wall after reacting with limulus reagent, so the method is called limulus reagent gel detection method. However, the complete limulus reagent detection kit is not sold in the market so far, and a detector needs to purchase related reagent consumables respectively in the early stage of relevant detection, such as limulus reagent, a working standard product, an empty ampoule bottle for removing a heat source and the like, the process is complicated, and factors such as different reagent manufacturers and different batch numbers of the same reagent have certain influence on the detection result.

SUMMERY OF THE UTILITY MODEL

The main objective of the utility model is to provide a bacterial endotoxin detect reagent box for this reagent box easy operation is convenient, portable preserves, can effectively reduce the preliminary preparation work of detection person, and makes the experimental result more accurate reliable.

In order to achieve the above object, the utility model provides a bacterial endotoxin detect reagent box, include:

the box body is used for accommodating reagent consumables related to bacterial endotoxin detection, the box body is provided with a front surface and a back surface which are oppositely arranged, and the top of the front surface is provided with a first magnetic part;

the box cover is connected with the top end of the back face, a second magnetic piece is arranged at one end, away from the back face, of the box cover, the box cover is covered with the box body and is tightly covered through the first magnetic piece and the second magnetic piece in a matched mode;

the fixed plate, horizontal installation can be dismantled to the fixed plate in the box body, seted up on the fixed plate and put the thing hole, it is fixed with a bacterial endotoxin standard substance reagent ampoule to put the thing hole, a bacterial endotoxin inspection water ampoule, eight limulus reagent ampoules, three pyrogen-free empty ampoules.

Optionally, one end of the box cover, which is far away from the back surface, is provided with a folded edge, and the second magnetic member is arranged on the folded edge.

Optionally, the bacterial endotoxin detection kit is further provided with a plurality of pyrogen-free tips.

Alternatively, the pyrogen-free tip is a 200. mu.l tip and a 1000. mu.l tip.

The utility model discloses technical scheme is through designing a bacterial endotoxin detect reagent box, the box body and the lid of this kit pass through the magnetic part lid tightly, conveniently open and close with the lid, be provided with the fixed plate in the box body, be fixed with reagent and the consumptive material that are used for bacterial endotoxin detection experiment to be relevant on the fixed plate, through using this kit, need not prepare relevant reagent consumptive material alone before carrying out bacterial endotoxin detection test, make experiment convenient operation, reduce the work of preparing in earlier stage, and avoid different reagent producers, the different wholesale numbers of same reagent cause the influence to the testing result.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the structures shown in the drawings without creative efforts.

FIG. 1 is a schematic structural diagram of the bacterial endotoxin detection kit of the present invention.

The reference numbers illustrate:

the objects, features and advantages of the present invention will be further described with reference to the accompanying drawings.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

It should be noted that all the directional indicators (such as upper, lower, left, right, front, and rear … …) in the embodiment of the present invention are only used to explain the relative position relationship between the components, the motion situation, etc. in a specific posture, if the specific posture is changed, the directional indicator is changed accordingly.

In the present application, unless expressly stated or limited otherwise, the terms "connected" and "fixed" are to be construed broadly, e.g., "fixed" may be fixedly connected or detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.

In addition, descriptions in the present application as to "first", "second", and the like are for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicit to the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, the technical solutions in the embodiments may be combined with each other, but it must be based on the realization of those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should not be considered to exist, and is not within the protection scope of the present invention.

The utility model provides a bacterial endotoxin detect reagent box, through using this kit, need not prepare relevant reagent consumptive material alone before carrying out bacterial endotoxin detection test, make experiment convenient operation, reduce preparation work in earlier stage to the different wholesale numbers of avoiding different reagent producers, same reagent cause the influence to the testing result.

Referring to fig. 1, fig. 1 is a schematic structural diagram of the bacterial endotoxin detection kit of the present invention.

In an embodiment of the present invention, please refer to fig. 1, which provides a bacterial endotoxin detection kit 100, comprising: the box body 10 is used for accommodating reagent consumables related to bacterial endotoxin detection, the box body 10 is provided with a front surface 12 and a back surface 14 which are oppositely arranged, and a first magnetic part 121 is arranged on the top of the front surface 12; the box cover 20 is connected with the top end of the back 14, one end of the box cover 20, which is far away from the back 14, is provided with a second magnetic part 22, the box cover 20 is covered with the box body 10, and the first magnetic part 121 and the second magnetic part 22 are matched and tightly covered; fixed plate 30, fixed plate 30 can dismantle horizontal installation in the box body 10, set up on the fixed plate 30 and put the thing hole, it is fixed with a bacterial endotoxin standard substance reagent ampoule 32 to put the thing hole, a bacterial endotoxin inspection is with water ampoule 34, eight limulus reagent ampoules 36, three empty ampoule 38 of pyrogen free.

Specifically, referring to fig. 1, the shape of the reagent cartridge body 10 may be square, rectangular, circular, etc., and is not limited herein. More specifically, the box body 10 and the box cover 20 may be integrally connected, or may be connected by a hinge, etc., as long as it is ensured that the box cover 20 can be turned to close and open the box body 10.

Specifically, referring to fig. 1, in order to improve the reliability of the cover of the box cover 20 and the box body 10, a first magnetic member 121 is disposed on the top of the front surface 12 of the box body 10, and a second magnetic member 22 is disposed at the end of the box cover 20, so that when the box cover 20 and the box body 10 are covered together, the first magnetic member 121 and the second magnetic member 22 are attached together, so that the bacterial endotoxin detection kit 100 is more tightly covered, and is more convenient to open, thereby improving the operability of the kit. The first magnetic member 121 and the second magnetic member 22 may be configured as a magnet or a ferromagnetic material, and the ferromagnetic material may be iron, cobalt, nickel, and preferably iron. Specifically, when the first magnetic member 121 is a magnet, the second magnetic member 22 may be a magnet or a ferromagnetic material, and when the first magnetic member 121 is a ferromagnetic material, the second magnetic member 22 is a magnet. The sizes of the first magnetic element 121 and the second magnetic element 22 can be set arbitrarily, as long as the box body 10 and the box cover 20 are tightly covered.

Specifically, one ampoule bottle 32 for bacterial endotoxin standard reagent is used for containing bacterial endotoxin standard reagent and is used for configuring experiment positive control and test article positive control, and one ampoule bottle 32 for bacterial endotoxin standard reagent can save cost. The bacterial endotoxin standard substance is set to be 10 EU/count, can be automatically diluted according to requirements during detection, and has wider application range.

Specifically, one ampoule bottle 34 for bacterial endotoxin test water is used for containing the bacterial endotoxin test water, dissolving a bacterial endotoxin working standard substance, diluting the standard substance and diluting a test substance, and configuring a negative control and a test substance negative control.

Specifically, the eight limulus reagent ampoules 36 are used for containing limulus reagents, and the eight limulus reagents are respectively used as a positive control, a negative control, a test article positive control and a test article negative control, namely two limulus reagents.

Specifically, three-piece pyrogen-free empty ampoule 38 is used for diluting the standard and test substances.

The utility model discloses technical scheme is through designing a bacterial endotoxin detect reagent box 100, the box body 10 and the lid 20 of this kit pass through the magnetic part lid tightly, conveniently open and close with the lid, be provided with fixed plate 30 in the box body 10, be fixed with reagent and the consumptive material that are used for bacterial endotoxin to detect that the experiment is relevant on the fixed plate 30, through using this kit, need not prepare relevant reagent consumptive material alone before carrying out bacterial endotoxin detection test, make experiment convenient operation, reduce the preparation work in earlier stage, and avoid different reagents, the different wholesale numbers of the same reagent of producer cause the influence to the testing result.

Optionally, referring to fig. 1, a folded edge 24 is disposed at an end of the box cover 20 away from the back 14, and the second magnetic member 22 is disposed at the folded edge 24. The folded edge 24 is attached to the front surface 12 of the box body 10, and the second magnetic member 22 is arranged at the folded edge 24 by arranging the folded edge 24, so that the tight covering between the box cover 20 and the box body 10 is further improved.

Optionally, the bacterial endotoxin detection kit 100 is further provided with a plurality of pyrogen-free tips. Specifically, referring to fig. 1, the fixing plate 30 is provided with a placement groove 39 for placing the pyrogen-free pipette tips, and the pipette tips are fixed by the placement groove 39 to prevent the pipette tips from colliding with the reagent bottles.

Alternatively, the pyrogen-free tip is a 200. mu.l tip and a 1000. mu.l tip. The suction heads with different specifications are provided, and the experimental operation is convenient.

The above is only the optional embodiment of the present invention, and not the scope of the present invention is limited thereby, all the equivalent structure changes made by the contents of the specification and the drawings are utilized under the inventive concept of the present invention, or the direct/indirect application in other related technical fields is included in the patent protection scope of the present invention.

Claims (4)

1. A bacterial endotoxin detection kit (100) comprising:

the box body (10) is used for accommodating reagent consumables related to bacterial endotoxin detection, the box body (10) is provided with a front surface (12) and a back surface (14) which are oppositely arranged, and a first magnetic part (121) is arranged at the top of the front surface (12);

the box cover (20), the box cover (20) is connected with the top end of the back face (14), one end, far away from the back face (14), of the box cover (20) is provided with a second magnetic part (22), the box cover (20) is covered with the box body (10), and the first magnetic part (121) and the second magnetic part (22) are matched and tightly covered;

fixed plate (30), horizontal installation can be dismantled in fixed plate (30) in box body (10), seted up on fixed plate (30) and put the thing hole, it is provided with a bacterial endotoxin standard reagent ampoule (32) to put the thing hole, a bacterial endotoxin inspection water ampoule (34), eight limulus reagent ampoules (36), three pyrogen-free empty ampoules (38).

2. A bacterial endotoxin detection kit (100) as claimed in claim 1 wherein the end of the lid (20) remote from the rear face (14) is provided with a flange (24) and the second magnetic member (22) is provided on the flange (24).

3. A bacterial endotoxin detection kit (100) as claimed in claim 1 wherein the bacterial endotoxin detection kit (100) is further provided with pyrogen-free tips.

4. A bacterial endotoxin detection kit (100) according to claim 3 wherein the pyrogen-free tip is a 200. mu.l tip or a 1000. mu.l tip.

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