CN212547765U - Chitosan quaternary ammonium salt sterilization band-aid - Google Patents

Chitosan quaternary ammonium salt sterilization band-aid Download PDF

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Publication number
CN212547765U
CN212547765U CN202020339137.0U CN202020339137U CN212547765U CN 212547765 U CN212547765 U CN 212547765U CN 202020339137 U CN202020339137 U CN 202020339137U CN 212547765 U CN212547765 U CN 212547765U
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layer
quaternary ammonium
ammonium salt
chitosan quaternary
iodophor
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CN202020339137.0U
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程国钢
马洁
赵刚
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Tianjin Kangting Biological Engineering Group Co Ltd
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Tianjin Kangting Biological Engineering Group Co Ltd
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Abstract

The utility model relates to a chitosan quaternary ammonium salt adhesive bandage that disinfects, including supporting layer, cover membrane, its characterized in that: the chitosan quaternary ammonium salt dressing bag is arranged between the supporting layer and the covering film, the chitosan quaternary ammonium salt dressing bag is sequentially provided with a cold coating layer, a water absorbing layer, a chitosan quaternary ammonium salt sterilizing layer and an iodophor layer by depending on the supporting layer, and the covering film completely covers the supporting layer and the chitosan quaternary ammonium salt dressing bag. The utility model discloses newly use chitosan quaternary ammonium salt dressing package in the band-aid, and increased iodophor layer and cold coating, use comfortable softness, have good ventilative moisture absorption, detumescence, hemostasis function, and nontoxic, tasteless, no stimulation, no corruption, pollution-free, belong to the medical product of environment-friendly type. The preparation process is simple, no large amount of equipment is required to be purchased, the cost is low, the large-scale industrialization is easy to realize, the product price is low, and the clinical use effect is good.

Description

Chitosan quaternary ammonium salt sterilization band-aid
Technical Field
The utility model belongs to medical consumptive material field relates to the gauze that disinfects, especially a chitosan quaternary ammonium salt adhesive bandage that disinfects.
Background
The woundplast is one of the most common surgical medicines in human life. The band-aid, also called as hemostatic plaster, has the functions of hemostasis and wound protection. It is made up by using a long adhesive tape and a small piece of yarn soaked with medicine through the middle portion of said adhesive tape.
Due to the structural limitation of the band-aid, the band-aid can only be used for emergency treatment of small wounds, thereby playing the roles of temporary hemostasis and wound surface protection. The band-aid in the prior art has more use problems:
if the adhesive tape is used for a long time, the skin around the wound and the wound is whitened and softened to cause secondary infection of bacteria, so that the wound is further deteriorated. In addition, the wound surface of a patient is accompanied by pain, the existing band-aid can bring friction pain to the patient when contacting the wound surface of the patient, and the use comfort is not good.
Chitosan is a natural cationic basic polysaccharide, chemically known as β - (1-4) -2-amino-2-deoxy-D-glucan, a polymer obtained from the stepwise deacetylation of chitin. Chitin is widely present in organisms such as shells of higher fungi, arthropod shrimps, crabs and insects in the nature, has a very large storage amount on the earth, and is the second largest biological resource in the nature. Chitosan has many biological properties: such as safety, innocuity, anti-tumor, bacteriostasis, biodegradability, biocompatibility and the like. Because the chitosan is a pure natural substance and has very similar biological properties with cellulose and collagen, the chitosan has good biocompatibility with cells and tissues and organs of a human body; has excellent biodegradability, can be completely absorbed in vivo and directly utilized; for damaged tissue cells, chitosan is effective in promoting their regeneration and accelerating healing.
However, chitosan has a large amount of intramolecular and intermolecular hydrogen bonds, so that chitosan is not dissolved in water and dilute alkali solution, is not dissolved in common organic solvent, and is only dissolved in low-concentration inorganic acid acidic solution such as dilute acetic acid and dilute hydrochloric acid (pH <6) and individual organic solvent, so that the application of chitosan in the field of hemostatic dressings is greatly limited.
Through a search of the prior published patent documents, no published patent document similar to the technical features of the patent is found.
SUMMERY OF THE UTILITY MODEL
The utility model aims to overcome prior art's weak point, provide an utilize chitosan quaternary ammonium salt to disinfect, effectively improve bactericidal effect and increase use comfort's chitosan quaternary ammonium salt woundplast that disinfects.
The utility model provides a its technical problem take following technical scheme to realize:
the chitosan quaternary ammonium salt sterilization band-aid comprises a supporting layer and a covering film, wherein a chitosan quaternary ammonium salt dressing bag is arranged between the supporting layer and the covering film, the chitosan quaternary ammonium salt dressing bag is sequentially provided with a cold coating layer, a water absorption layer, a chitosan quaternary ammonium salt sterilization layer and an iodophor layer by virtue of the supporting layer, and the covering film completely covers the supporting layer and the chitosan quaternary ammonium salt dressing bag.
And the iodophor layer comprises a plurality of unit gel balls filled with iodophor liquid, the matrix of the iodophor layer is gel, the upper layer of the iodophor layer is covered with a tearing layer matched with the covering film, the tearing layer comprises an A glue layer adhered to the iodophor layer and a B glue layer adhered to the covering layer, and the B glue layer is adhered to the A glue layer.
And the adhesive layers are arranged on the two sides of the chitosan quaternary ammonium salt dressing bag on the supporting layer, and are matched with the covering film to form an adhesive part of the woundplast.
Moreover, the sticking part is provided with a plurality of air holes for increasing the use air permeability.
Moreover, the water absorption layer is medical gauze.
The utility model has the advantages that:
1. the cold coating of the chitosan quaternary ammonium salt dressing bag is prepared by taking a high-molecular hydrogel material as a matrix, contains natural cool traditional Chinese medicine components, takes away heat after contacting air for vaporization, and can achieve the effect of local cooling, and the medicine can quickly penetrate through a fat layer through the medicine components after the hydrogel is combined, and then permeates into subcutaneous tissues to directly reach focuses, so that the effects and effects of cold compress pain relief, percutaneous absorption and sustained release administration are achieved.
2. The iodophor layer of the chitosan quaternary ammonium salt dressing bag is composed of a plurality of unit gel balls filled with iodophor liquid, the matrix of the iodophor layer is gel, the iodophor liquid in the unit gel layer is released to achieve the effects of disinfecting and sterilizing wounds and improving the use comfort, and the sterilization effect of the chitosan quaternary ammonium salt sterilization layer can be promoted.
3. The water absorbing layer of the chitosan quaternary ammonium salt dressing bag mainly absorbs redundant moisture, the adhesive tape can keep dry and comfortable in the long-time use process of the adhesive tape, the adhesive tape on the outer layer of the adhesive tape is not breathable, so that a wound and skin around the wound are whitened, the skin is softened to cause secondary infection of bacteria, and the wound can be further deteriorated.
4. The chitosan quaternary ammonium salt adopted in the chitosan quaternary ammonium salt dressing bag is 2-hydroxypropyl trimethyl ammonium chloride chitosan, the chitosan quaternary ammonium salt dressing bag is prepared by chemically modifying chitosan, the water solubility is good, the application range of the chitosan is enlarged, the used 2-hydroxypropyl trimethyl ammonium chloride chitosan not only plays the advantages of wide chitosan source and the like, but also mainly inherits the sterilization characteristic of the chitosan, can be well combined with common gauze, effectively reduces the infection rate of wounds and promotes healing.
5. The utility model discloses newly use chitosan quaternary ammonium salt dressing package in the band-aid, and increased iodophor layer and cold coating, use comfortable softness, have good ventilative moisture absorption, detumescence, hemostasis function, and nontoxic, tasteless, no stimulation, no corruption, pollution-free, belong to the medical product of environment-friendly type. The preparation process is simple, no large amount of equipment is required to be purchased, the cost is low, the large-scale industrialization is easy to realize, the product price is low, and the clinical use effect is good.
Drawings
Fig. 1 is a front view of the present invention;
fig. 2 is a schematic diagram of the chitosan quaternary ammonium salt dressing bag in fig. 1.
Detailed Description
The present invention will be described in further detail with reference to the following embodiments, which are illustrative, not restrictive, and the scope of the invention should not be limited thereto.
A chitosan quaternary ammonium salt sterilization band-aid is characterized in that a chitosan quaternary ammonium salt dressing bag 5 is arranged between a supporting layer and a covering film as shown in figure 1, as shown in figure 2, the chitosan quaternary ammonium salt dressing bag is sequentially provided with a cold coating layer 9, a water absorbing layer 10, a chitosan quaternary ammonium salt sterilization layer 11 and an iodophor layer 7 by means of the supporting layer, the cold coating layer is prepared by taking a high-molecular hydrogel material as a matrix, contains natural cool traditional Chinese medicine components, takes away heat after contacting with air and vaporizing, and can achieve the effect of local cooling, and after hydrogel is combined, medicaments can rapidly penetrate through a fat layer through the medicament components, permeate into subcutaneous tissues and reach focuses directly, so that the effects and effects of cold coating pain relief, percutaneous absorption and sustained-release administration are achieved.
The water absorbing layer is common medical gauze, and the preparation method of the chitosan quaternary ammonium salt sterilizing layer comprises the following steps: preparing a chitosan quaternary ammonium salt into an aqueous solution with the concentration of 4mg/mL, immersing and mixing gauze at the temperature of 37 ℃ for 2 hours, removing liquid, and drying; and soaking the gauze in 6mg/mL chitosan quaternary ammonium salt water solution for 5 hours, removing the solution, shaping, and drying for the second time, wherein the chitosan quaternary ammonium salt used in the embodiment is 2-hydroxypropyl trimethyl ammonium chloride chitosan.
The iodophor layer constitute by a plurality of unit gel balls 8 that fill the iodophor liquid, its matrix is the gel, its upper strata covers and covers the tearing layer that the cooperation of covering membrane was used, the layer of tearing including pasting A glue film 6 on the iodophor layer and pasting B glue film 1 on the overburden, the B glue film bonds with A glue film, tears the overburden during the use, along with taking B glue film to tear the A glue film, the iodophor liquid in the unit gel ball leaches, improves use comfort when giving wound disinfection and sterilization, and can promote chitosan quaternary ammonium salt bactericidal layer's bactericidal efficiency.
The adhesive layer 3 is arranged on the supporting layer and on two sides of the chitosan quaternary ammonium salt dressing bag, and is matched with the covering film to form an adhesive part of the adhesive bandage, and a plurality of air holes (not shown in the figure) are formed in the adhesive part to increase the use air permeability.
The supporting layer, the covering film and the chitosan quaternary ammonium salt dressing bag are manufactured by a physical pressing process, and the supporting layer and the chitosan quaternary ammonium salt dressing bag are completely covered by the covering film.
Although the embodiments of the present invention and the accompanying drawings are disclosed for illustrative purposes, those skilled in the art will appreciate that: various substitutions, changes and modifications are possible without departing from the spirit and scope of the present invention and the appended claims, and therefore, the scope of the present invention is not limited to the disclosure of the embodiments and the accompanying drawings.

Claims (5)

1. The chitosan quaternary ammonium salt sterilization band-aid comprises a supporting layer and a covering film, and is characterized in that: the chitosan quaternary ammonium salt dressing bag is arranged between the supporting layer and the covering film, the chitosan quaternary ammonium salt dressing bag is sequentially provided with a cold coating layer, a water absorbing layer, a chitosan quaternary ammonium salt sterilizing layer and an iodophor layer by depending on the supporting layer, and the covering film completely covers the supporting layer and the chitosan quaternary ammonium salt dressing bag.
2. The chitosan quaternary ammonium salt sterilization adhesive bandage of claim 1, which is characterized in that: the iodophor layer comprises a plurality of unit gel balls filled with iodophor liquid, the matrix of the iodophor layer is gel, the upper layer of the iodophor layer is covered with a tearing layer matched with the covering film for use, the tearing layer comprises an A glue layer adhered to the iodophor layer and a B glue layer adhered to the covering layer, and the B glue layer is adhered to the A glue layer.
3. The chitosan quaternary ammonium salt sterilization adhesive bandage of claim 1, which is characterized in that: the adhesive layer is arranged on the supporting layer and on two sides of the chitosan quaternary ammonium salt dressing bag, and the adhesive layer and the covering film are matched to form an adhesive part of the adhesive bandage.
4. The chitosan quaternary ammonium salt sterilization band-aid of claim 3, which is characterized in that: the pasting part is provided with a plurality of air holes for increasing the use air permeability.
5. The chitosan quaternary ammonium salt sterilization adhesive bandage of claim 1, which is characterized in that: the water absorption layer is medical gauze.
CN202020339137.0U 2020-03-18 2020-03-18 Chitosan quaternary ammonium salt sterilization band-aid Active CN212547765U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202020339137.0U CN212547765U (en) 2020-03-18 2020-03-18 Chitosan quaternary ammonium salt sterilization band-aid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202020339137.0U CN212547765U (en) 2020-03-18 2020-03-18 Chitosan quaternary ammonium salt sterilization band-aid

Publications (1)

Publication Number Publication Date
CN212547765U true CN212547765U (en) 2021-02-19

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202020339137.0U Active CN212547765U (en) 2020-03-18 2020-03-18 Chitosan quaternary ammonium salt sterilization band-aid

Country Status (1)

Country Link
CN (1) CN212547765U (en)

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