CN212432735U

CN212432735U - A rotary disk for automatic slide bearing of dyeing machine

Info

Publication number: CN212432735U
Application number: CN202021122240.6U
Authority: CN
Inventors: 吴楷
Original assignee: Guizhou Meixinda Medical Technology Co ltd
Current assignee: Guizhou Meixinda Medical Technology Co ltd
Priority date: 2020-06-17
Filing date: 2020-06-17
Publication date: 2021-01-29
Anticipated expiration: 2030-06-17

Abstract

The utility model provides a rotary disk for automatic slide staining machine bears slide, this rotary disk can bear a plurality of special slide card boxes, and this card box combines together with the slide that bears the tissue slice, and is rotatory through the location of rotary disk, and the structure is annotated in the cooperation, realizes various reaction liquid filling in slide card box, with the tissue reaction on the slide. The disc has a fixed receiving member, a rotating disc, a transmission mechanism, a waste liquid port and the like. The rotating disc is connected with a transmission structure at the bottom of the bearing piece to realize plane rotation motion. The utility model discloses structure cooperation slide card box and filling mechanism can realize dying the automation mechanized operation of piece flow. Its centrifugal structure cooperates with the functional rotation pattern to be realized in the cartridge: firstly, rotating and flattening liquid on the surface of a glass slide at a low speed; secondly, rotating and mixing the liquid in a positive and negative direction; thirdly, the quick centrifugal rotation realizes that the multiple card boxes can simultaneously and quickly throw away the waste liquid.

Description

A rotary disk for automatic slide bearing of dyeing machine

Technical Field

The utility model relates to a rotary disk, in particular to a rotary disk which is matched with a slide card box of a slide joint bearing paraffin section tissue, frozen section tissue or fresh tissue to carry out dyeing reaction.

Background

Immunohistochemistry is used for precise localized staining at the tissue molecular level and is widely applied to clinical pathological diagnosis. In order to more reliably and conveniently carry out immunohistochemical staining, a staining machine with an automatic flow process generally replaces the manual operation of immunohistochemistry. One common challenge in designing and manufacturing automatic sheeters is: 1) mechanical arms are needed to drive the tube pumps to suck and release reagents one by one and then clean the reagents, and the flow operations are sequentially overlapped in series, so that the time required by the slide dyeing process is multiplied along with the increase of the slide; 2) an alternative approach is to eliminate the mechanical arm and serial operation and use the liquid pump and tubing to simultaneously operate the staining of all slides in parallel, which greatly complicates tubing and liquid pump set-up as the number of slides increases and adds time and expense to the cleaning and maintenance of these tubing. Neither of these solutions enables the dyer to be able to increase the speed and maintain a simple and easy-to-maintain structure.

Disclosure of Invention

To foretell problem, the utility model provides a cooperation and the slide card box of the slide joint of bearing or frozen tissue section, paraffin section or fresh tissue carry out the rotary disk that immunohistochemical reaction was dyed, the cooperation is annotated the structure and is carried out the efficient automation mechanized operation of dyeing flow such as quick immunohistochemistry.

For solving the above-mentioned problem, plan to adopt such a rotary disk that is used for automatic dyeing machine to bear slide, including fixed receiving piece, the rotary disk, drive mechanism, the rotary disk level sets up, the tubular structure in the rotary disk outside is located for the cover to fixed receiving piece, the gap has between fixed receiving piece and the rotary disk, the waste liquid pipe has been drawn forth downwards to fixed receiving piece bottom below the rotary disk, drive mechanism sets up in the bottom of rotary disk and rotates in order to drive the rotary disk, along circumference distribution on the up end of rotary disk has seted up a plurality of joint mouths, the joint has slide card box subassembly in the joint mouth, the sealed joint has the slide that bears paraffin section tissue, frozen section tissue or fresh tissue in the slide card box subassembly.

In the rotating disc for bearing the glass slide by the automatic slide dyeing machine, the fixed bearing piece is of a circular cylindrical structure;

in the rotating disc for bearing the glass slides by the automatic slide dyeing machine, the clamping ports are distributed at equal intervals along the circumferential direction of the rotating disc, a glass slide box assembly is clamped and fixed in each clamping port, and the glass slides and reaction liquid are arranged in the glass slide box assemblies;

in the rotating disc for carrying the slide by the automatic slide dyeing machine, the rotating disc is also provided with an assembly for heating a single slide or a plurality of slides, and provides a specific temperature environment required by immunohistochemical reaction, tissue dewaxing and pretreatment or in-situ hybridization reaction on tissues;

in the aforementioned automatic slide dyeing machine bears the weight of the rotary disk of slide, still have the fretwork mouth on the rotary disk for cooperate the filling device to carry out the preflushing liquid operation, the discharged waste liquid of preflushing liquid can pass through the fretwork mouth drips into fixed receiving piece, retrieves to the waste liquid bucket via the waste liquid pipe, the fretwork mouth can also joint waste liquid groove, and special preliminary filling waste liquid can be retrieved to this waste liquid groove.

Compared with the prior art, the utility model has the advantages of as follows: 1) the slide card box can be assembled and disassembled quickly; 2) the automatic liquid injection device is matched with the liquid injection device in a rotating and positioning way to quickly receive liquid; 2) the low-speed rotation mode can realize the flattening of the liquid in the slide card box without any dead angle; 3) the mode of forward and reverse variable-speed rotation can realize the uniform mixing and the accelerated reaction of the liquid in the slide card box; 4) the waste liquid in the slide cartridge can be thrown away under the high rotating speed state, the batch quick removal of the waste liquid is realized, and the reaction time is shortened.

Drawings

Fig. 1 is a schematic three-dimensional structure of the rotating disk of the present invention.

FIG. 2 is a schematic view of the rotating disk of the present invention rotating at a low speed to flatten the liquid on the surface of the slide.

FIG. 3 is a schematic view of the rotating disk of the present invention rotating forward and backward at variable speeds to uniformly mix the liquid on the surface of the slide.

FIG. 4 is a schematic view of the rotating disk of the present invention rotating at high speed and throwing away the liquid on the surface of the slide.

Detailed Description

To further clarify the objects, technical solutions and advantages of the present invention, a more particular description of the invention will be rendered by reference to the appended drawings, which are illustrated in the appended drawings.

Examples

As shown in fig. 1, the rotary plate is composed of a fixed receiving member 5, a rotary plate 7, a transmission mechanism 9 and a waste liquid pipe 3.

In the embodiment, the fixed bearing part 5 is a cylindrical structure, the rotating disc 7 is positioned inside the fixed bearing part 5 and is in transmission connection with the transmission mechanism 9 at the bottom of the fixed bearing part 5, the transmission mechanism 9 is provided with a driving motor, the rotating disc 7 is driven by the driving motor to rotate forwards and backwards at different speeds, the fixed bearing part 5 and the rotating disc 7 are provided with a certain gap, the rotating disc 7 is provided with a plurality of bearing positions of the slide card box assembly 1, namely a card interface 2, and the slide card box assembly 1 is clamped and fixed on the card interface 2.

When the automatic filling mechanism works in a matched mode, the rotating disc 7 is attached with the slide card box assembly 1 to the bottom of the filling mechanism, the filling mechanism sprays liquid, the liquid enters the slide card box assembly 1 through a liquid filling opening of the slide card box assembly 1, and liquid filling is carried out on the slide card box assembly 1 on the rotating disc 7 in sequence.

As shown in fig. 2, after filling, the rotating disk 7 is rotated at a low speed, and the centrifugal force 10 flattens the reagent liquid 11 filled on the surface of the slide 12.

As shown in FIG. 3, the rotating disc 7 rotates forward and backward at a low speed, the centrifugal force 10 and the inertia force 13 uniformly mix the reaction liquid 11 on the slide 12 in the oscillating cartridge, and the staining reaction of the reaction liquid with the frozen section tissue, the paraffin section tissue or the fresh tissue is accelerated.

After the reaction is completed, the rotating disc 7 is accelerated to rotate, and the enhanced centrifugal force 10 makes the reaction liquid 11 (waste liquid) in the slide cartridge assembly 1 be thrown out through the waste liquid outlet at the tail end of the slide cartridge assembly and be thrown away to the circular side wall of the fixed carrier 5, and the waste liquid slides down to the bottom of the fixed carrier 5 along the gap between the side wall and the rotating disc 7, and is discharged through the waste liquid pipe 3 or transferred to a waste liquid barrel for recycling.

The rotating disc 7 is also provided with a hollow opening 8, when the filling mechanism performs pre-flushing, the filling end can be aligned with the hollow opening 8 for pre-flushing, and pre-filled waste liquid is discharged to the bottom of the fixed bearing part 5 through the hollow opening 8 and is transferred to a waste liquid barrel through the waste liquid pipe 3. Particularly, in this embodiment, the hollow opening 8 may further bear a special waste liquid tank 4, which may bear a special liquid not easy to be recovered for pre-flushing, such as gelatin, which may be used for automatic sheet sealing, and the pre-flushing liquid through the hollow opening 8 may cause the waste liquid pipe 3 to be blocked, and at this time, the special waste liquid tank 4 may be clamped on the hollow opening 8 to specially recover the pre-flushing liquid of the gelatin.

The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.

Claims

1. The utility model provides a rotary disk that is used for automatic staining mascerating machine to bear slide which characterized in that: including fixed receiving part (5), rotary disk (7), drive mechanism (9), rotary disk (7) level sets up, the tubular structure in rotary disk (7) outside is located for the cover to fixed receiving part (5), the gap has between fixed receiving part (5) and rotary disk (7), waste liquid pipe (3) have been drawn forth downwards to fixed receiving part (5) bottom of rotary disk (7) below, drive mechanism (9) set up and rotate with drive rotary disk (7) in the bottom of rotary disk (7), a plurality of joint mouths (2) have been seted up along circumference distribution on the up end of rotary disk (7), joint has glass slide card box subassembly (1) in joint mouth (2), glass slide card box subassembly (1) internal seal joint has the slide that bears paraffin section tissue, frozen section tissue or fresh tissue.

2. A rotary disk as claimed in claim 1, wherein: the fixed bearing piece (5) is of a circular cylindrical structure.

3. A rotary disk as claimed in claim 1, wherein: the glass slide clamping device is characterized in that the clamping ports (2) are formed in the circumferential equidistant distribution of the rotating disk (7), a glass slide clamping box assembly (1) is clamped and fixed in each clamping port (2), and a glass slide (12) and reaction liquid (11) are arranged in each glass slide clamping box assembly (1).

4. A rotary disk as claimed in claim 1, wherein: the rotating disc (7) is also provided with a hollow opening (8).

5. The rotary tray of claim 4, wherein: the hollow opening (8) is loaded with a waste liquid tank (4) to load liquid which is not easy to recover for pre-flushing.