CN212284005U - A reation kettle for azaindole production - Google Patents
A reation kettle for azaindole production Download PDFInfo
- Publication number
- CN212284005U CN212284005U CN202020637218.9U CN202020637218U CN212284005U CN 212284005 U CN212284005 U CN 212284005U CN 202020637218 U CN202020637218 U CN 202020637218U CN 212284005 U CN212284005 U CN 212284005U
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- China
- Prior art keywords
- rod
- puddler
- connecting rod
- stirring
- fixed
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 19
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical compound C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title claims abstract description 11
- 238000003756 stirring Methods 0.000 claims abstract description 90
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 230000002093 peripheral effect Effects 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 12
- 239000002994 raw material Substances 0.000 abstract description 4
- 230000000739 chaotic effect Effects 0.000 abstract description 3
- 239000000463 material Substances 0.000 description 7
- 230000008859 change Effects 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 125000005334 azaindolyl group Chemical group N1N=C(C2=CC=CC=C12)* 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 150000002391 heterocyclic compounds Chemical class 0.000 description 2
- -1 indole compound Chemical class 0.000 description 2
- 150000002475 indoles Chemical class 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- SIKJAQJRHWYJAI-UHFFFAOYSA-N benzopyrrole Natural products C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 239000012847 fine chemical Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 description 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 239000012257 stirred material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
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- Mixers Of The Rotary Stirring Type (AREA)
Abstract
The utility model provides a reation kettle for azaindole production, which comprises a tank body, the inside quick-witted case of the jar body, machine incasement portion is fixed with branch, the both ends that have bracing piece and bracing piece on the branch rotate respectively and install first connecting rod and second connecting rod, there are first guide arm and second guide arm on the machine case, all be equipped with the stirring subassembly on first guide arm and the second guide arm back of the body, the stirring subassembly is including fixing the fixed block on first guide arm and second guide arm respectively, it installs a plurality of puddlers to rotate on the fixed block, be fixed with the carousel on the output that quick-witted incasement is fixed with agitator motor and agitator motor, it has the third connecting rod to rotate on the carousel, the rotation junction that the carousel was kept away from to the third connecting rod rotates between one end and the bracing piece and is connected and the third connecting rod and. Can carry out the efficient stirring through the puddler of a plurality of rotations connections for jar raw materials of internal portion carry out chaotic motion, improve production efficiency, and excellent in use effect, device long service life.
Description
Technical Field
The utility model relates to a reation kettle equipment technical field especially relates to a reation kettle for azaindole production.
Background
The indole compound is an important branch in heterocyclic compounds, has various biological activities, and is the heterocyclic compound which is most widely distributed in nature. Indole compounds are important organic chemical raw materials and products, can be used as intermediates of medicines, pesticides, dyes, spices and other fine chemical products, and have wide application in a plurality of fields. Azaindoles can be regarded as bioisosteres of indoles, so that azaindoles play an important role in designing and synthesizing pharmaceutically active molecules. In the aspect of pharmacological action, the azaindole compound has the functions of resisting cancer, bacteria and viruses, treating hypertension and the like. The azaindole derivative can inhibit the activity of a plurality of proteases, has potential biological activity and medicinal value, and can treat a plurality of diseases such as cardiovascular diseases, tumors, diabetes and the like. Azaindole needs to react in the reation kettle in process of production to need stir it, but present reation kettle's stirring effect is relatively poor, leads to stirring time to increase, and production efficiency is low.
SUMMERY OF THE UTILITY MODEL
To above-mentioned condition, for overcoming prior art's defect, the utility model aims at providing a reation kettle for azaindole production can improve production efficiency to improve the effect of stirring.
The reaction kettle comprises a cylindrical tank body, a driving motor is arranged above the tank body, a driving shaft is arranged on the tank body in a rotating mode, the driving shaft and the tank body are coaxially arranged, one end of the driving shaft is connected with the output end of the driving motor, a cylindrical case is arranged inside the tank body, the case and the tank body are coaxially arranged, one side, close to the driving motor, of the case is fixedly connected with the driving shaft, a supporting rod is fixed inside the case, the supporting rod and the driving shaft are coaxially fixed, a supporting rod is arranged on one end, far away from the driving shaft, of the supporting rod in a rotating mode, two ends of the supporting rod are respectively provided with a first connecting rod and a second connecting rod in a rotating mode, the supporting rod is located between the first connecting rod and the second connecting rod, one side, far away from the supporting rod, of the case is provided with a first guide rod and a second guide rod in a, one ends of the first guide rod and the second guide rod, which are far away from the support rod, extend out of the case, and one ends of the first guide rod and the second guide rod, which extend out of the case, are respectively provided with a stirring assembly, one end of the first guide rod and the second guide rod, which is far away from the support rod, is rotatably connected with the first guide rod, one end of the second guide rod, which is far away from the support rod, is rotatably connected with the second guide rod, the stirring assembly comprises fixed blocks which are respectively fixed on the first guide rod and the second guide rod, a first stirring rod and a second stirring rod are rotatably installed on the fixed blocks, the free ends of the first stirring rod and the second stirring rod are respectively rotatably connected with a third stirring rod and a fourth stirring rod, one end of the third stirring rod, which is far away from the first stirring rod, is rotatably connected with a fifth stirring rod, one end of the fourth stirring rod, which is far away from the second stirring rod, the quick-witted case deviates from and is fixed with the ejector pin and the ejector pin of driving shaft coaxial line on the one side of driving shaft and keeps away from one of quick-witted case and serve and be fixed with the circular shape backup pad, the coaxial line is fixed between backup pad and the ejector pin and the rotation junction of fifth puddler and sixth puddler is located the top of backup pad, the below that is equipped with feed inlet and jar body on the jar body is equipped with the discharge gate, be fixed with the carousel on quick-witted incasement is fixed with agitator motor and agitator motor's the output, rotate on the carousel and have the rotation junction of third connecting rod and carousel to keep away from the centre of a circle of carousel, the third connecting rod is kept away from between the one end of carousel and the bracing piece and is rotated and be.
Preferably, a plurality of sliding blocks are fixed on the peripheral wall of the case, a sliding groove is formed in the tank body, and the sliding blocks are connected with the sliding groove in a sliding mode.
Preferably, a plurality of stirring rods are fixed on the third stirring rod and the fourth stirring rod respectively.
The utility model has the advantages that: can carry out abundant stirring to the material, improve production efficiency. Rotation through a plurality of stirs is connected for the stirring effect can carry out continuous change, makes the motion of material more chaotic when stirring the material, thereby improves stirring efficiency, and the slider can increase the stability of device when stirring, and device excellent in use effect, long service life.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention.
Detailed Description
The following describes the embodiments of the present invention in further detail with reference to the accompanying drawings.
Given by figure 1, a reaction kettle for azaindole production comprises a cylindrical tank body 1 and is characterized in that a driving motor 2 is arranged above the tank body 1, a driving shaft 3 is rotatably arranged on the tank body 1, the driving shaft 3 and the tank body 1 are coaxially arranged, one end of the driving shaft 3 is connected with the output end of the driving motor 2, a cylindrical case 4 is arranged inside the tank body 1, the case 4 and the tank body 1 are coaxially arranged, one side of the case 4 close to the driving motor 2 is fixedly connected with the driving shaft 3, a supporting rod 5 is fixed inside the case 4, the supporting rod 5 and the driving shaft 3 are coaxially fixed, a supporting rod 6 is rotatably arranged on one end of the supporting rod 5 far away from the driving shaft 3, a first connecting rod 10 and a second connecting rod 7 are respectively rotatably arranged at two ends of the supporting rod 6, and the supporting rod 6 is positioned between the first connecting rod 10 and the second connecting, a first guide rod 11 and a second guide rod 8 are slidably mounted on one surface of the case 4 deviating from the support rod 5, the axes of the first guide rod 11 and the second guide rod 8 are parallel to the axis of the support rod 5, the ends of the first guide rod 11 and the second guide rod 8 deviating from the support rod 5 extend out of the case 4, the ends of the first guide rod 11 and the second guide rod 8 extending out of the case 4 are respectively provided with a stirring component, one end of the first connecting rod 10 far away from the support rod 6 is rotatably connected with the first guide rod 11, one end of the second connecting rod 7 far away from the support rod 6 is rotatably connected with the second guide rod 8, the stirring component comprises a fixed block 9 respectively fixed on the first guide rod 11 and the second guide rod 8, a first stirring rod 17 and a second stirring rod 18 are rotatably mounted on the fixed block 9, and the free ends of the first stirring rod 17 and the second stirring rod are respectively rotatably connected with a third stirring rod 19 and a fourth stirring rod 20, the end of the third stirring rod 19 far away from the first stirring rod 17 is rotatably connected with a fifth stirring rod 21, the end of the fourth stirring rod 20 far away from the second stirring rod 18 is rotatably connected with a sixth stirring rod 22, the free ends of the fifth stirring rod 21 and the sixth stirring rod 22 are rotatably connected, one surface of the case 4 far away from the driving shaft 3 is fixedly provided with a mandril 15 coaxial with the driving shaft 3, the end of the mandril 15 far away from the case 4 is fixedly provided with a circular support plate 16, the support plate 16 and the mandril 15 are coaxially fixed, the rotating joint of the fifth stirring rod 21 and the sixth stirring rod 22 is positioned above the support plate 16, the case body 1 is provided with a feed inlet 23, a discharge outlet 24 is arranged below the case body 1, a stirring motor 14 is fixed in the case 4, a rotary table 13 is fixed at the output end of the stirring motor 14, a third connecting rod 12 is rotated on the rotary table 13, and the rotating joint of the third connecting rod 12 and the rotary table 13 is far away, one end of the third connecting rod 12, which is far away from the rotating disc 13, is rotatably connected with the supporting rod 6, and the rotating connection position of the third connecting rod 12 and the supporting rod 6 is positioned between the supporting rod 5 and the first connecting rod 10.
When the device is used, the device is firstly placed at a position needing to work, then the power is switched on, the driving motor 2 and the stirring motor 14 are switched on, then materials are added into the tank body 1 through the feed inlet 23, the driving motor 2 rotates to drive the driving shaft 3 to rotate, the driving shaft 3 is fixedly connected with the case 4, so that the case 4 can be driven to rotate in the tank body 1 by the rotation of the driving shaft 3, the case 4 can rotate due to the coaxial installation between the case 4 and the tank body 1, the rotating supporting rod 6 is arranged in the case 4, the supporting rod 6 can realize the purpose of moving up and down through the action of the stirring motor 14 and the third connecting rod 12, the first connecting rod 10 and the second connecting rod 7 are rotatably connected on the supporting rod 6, and the first connecting rod 11 and the second connecting rod 8 are rotatably connected to the first connecting rod 10 and the second connecting rod 7 respectively, therefore, the up-and-down movement of the first guide rod 11 and the second guide rod 8 can be realized, the fixed block 9 is fixed on each of the first guide rod 11 and the second guide rod 8, the first stirring rod 17 and the second stirring rod 18 are rotated on the fixed block 9, the plurality of stirring rods can form a polygonal structure and are rotatably connected with each other, so that the distance between the third stirring rod 19 and the fourth stirring rod 20 can be changed in the process that the fixed block 9 moves up and down along with the guide rods, the stirring range can be changed, the connecting part of the fifth stirring rod 21 and the sixth stirring rod 22 can be supported by the support rod 6 below the case 4, the stirring range can be changed by the plurality of stirring rods, and meanwhile, the stirring assembly rotates along with the rotation of the case 4, so that the purpose of stirring the raw materials in the tank body 1 can be realized, and the stirring scope of stirring subassembly is continuous changes, make the stirring effect obtain the increase, be equipped with two sets of stirring subassemblies in jar body 1, and two sets of stirring subassemblies appear tensile one under the effect of bracing piece 6 and present the phenomenon of shortening, thereby avoid a plurality of puddlers phenomenon of collision to appear when using, the life of device has been improved, the continuous change that carries out the stirring scope of stirring subassembly of two sets of while, further improvement the effect of stirring, make the continuous irregular mixture that carries out of the raw materials of jar body 1 inside, and the production efficiency is improved. The stirred material is discharged through a discharge port 24 at the lower part.
A plurality of sliding blocks 26 are fixed on the peripheral wall of the case 4, a sliding groove is arranged in the tank body 1, and the sliding blocks 26 are connected with the sliding groove in a sliding manner.
In order to increase the stability of the case 4 during rotation, a plurality of sliding blocks 26 are fixed on the peripheral wall of the case 4, and the tank 1 is provided with a sliding groove, so that the sliding blocks 26 slide in the sliding groove, the stability of the case 4 during rotation is improved, the production efficiency is increased, and the service life of the device is prolonged.
A plurality of stirring rods 25 are fixed on the third stirring rod 19 and the fourth stirring rod 20.
In order to further increase the production efficiency, a plurality of stirring rods 25 are fixed on the third stirring rod 19 and the fourth stirring rod 20, so that the stirring effect is improved, and the production efficiency is improved.
The utility model has the advantages that: can carry out abundant stirring to the material, improve production efficiency. Rotation through a plurality of stirs is connected for the stirring effect can carry out continuous change, makes the motion of material more chaotic when stirring the material, thereby improves stirring efficiency, and the slider can increase the stability of device when stirring, and device excellent in use effect, long service life.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Claims (3)
1. A reaction kettle for azaindole production comprises a cylindrical tank body (1) and is characterized in that a driving motor (2) is arranged above the tank body (1) and a driving shaft (3) is rotatably arranged on the tank body (1), the driving shaft (3) and the tank body (1) are coaxially arranged, one end of the driving shaft (3) is connected with the output end of the driving motor (2), a cylindrical case (4) is arranged inside the tank body (1) and the case (4) and the tank body (1) are coaxially arranged, one side of the case (4) close to the driving motor (2) is fixedly connected with the driving shaft (3), a supporting rod (5) and the supporting rod (5) are fixed with the driving shaft (3) in a coaxial manner, a supporting rod (6) is rotatably arranged on one end of the supporting rod (5) far away from the driving shaft (3), two ends of the supporting rod (6) are respectively rotatably arranged with a first connecting rod (10) and a second connecting rod (7), the supporting rod (6) is positioned between a first connecting rod (10) and a second connecting rod (7), a first guide rod (11) and a second guide rod (8) are slidably mounted on one surface of the case (4) departing from the supporting rod (5), the axes of the first guide rod (11) and the second guide rod (8) are parallel to the axis of the supporting rod (5), one ends of the first guide rod (11) and the second guide rod (8) departing from the supporting rod (5) extend out of the case (4), one ends of the first guide rod (11) and the second guide rod (8) extending out of the case (4) are respectively provided with a stirring assembly, one end of the first connecting rod (10) far away from the supporting rod (6) is rotatably connected with the first guide rod (11), one end of the second connecting rod (7) far away from the supporting rod (6) is rotatably connected with the second guide rod (8), the stirring assembly comprises a fixing block (9) fixed on the first guide rod (11) and the second guide rod (8), rotate on fixed block (9) and install first puddler (17) and second puddler (18) and first puddler (17) and second stirring and rotate respectively on the free end and be connected with third puddler (19) and fourth puddler (20), the one end that first puddler (17) were kept away from in third puddler (19) is rotated and is connected with fifth puddler (21) just the one end that second puddler (18) were kept away from in fourth puddler (20) is rotated and is connected with sixth puddler (22), rotates between the free end of fifth puddler (21) and sixth puddler (22) and is connected, be fixed with on one end of keeping away from quick-witted case (4) with ejector pin (15) and ejector pin (15) of driving shaft (3) coaxial line and be fixed with circular shape backup pad (16) on backup pad (16) and the coaxial line between ejector pin (15) and the rotation junction that fifth puddler (21) and sixth puddler (22) are located a branch The top of fagging (16), be equipped with feed inlet (23) on the jar body (1) and the below of the jar body (1) is equipped with discharge gate (24), be fixed with carousel (13) on the output that quick-witted case (4) internal fixation has agitator motor (14) and agitator motor (14), rotate on carousel (13) and have third connecting rod (12) and carousel (13) the rotation junction keep away from the centre of a circle of carousel (13), rotation connection and third connecting rod (12) and rotation junction that bracing piece (6) were kept away from between one end and bracing piece (6) of carousel (13) are located between branch (5) and first connecting rod (10) are kept away from in third connecting rod (12).
2. The reaction kettle for azaindole production according to claim 1, characterized in that a plurality of sliding blocks (26) are fixed on the peripheral wall of the case (4), a sliding groove is arranged inside the tank body (1), and the sliding blocks (26) are connected with the sliding groove in a sliding manner.
3. A reaction kettle for azaindole production according to claim 1, characterized in that a plurality of stirring rods (25) are fixed on the third stirring rod (19) and the fourth stirring rod (20).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020637218.9U CN212284005U (en) | 2020-04-24 | 2020-04-24 | A reation kettle for azaindole production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020637218.9U CN212284005U (en) | 2020-04-24 | 2020-04-24 | A reation kettle for azaindole production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN212284005U true CN212284005U (en) | 2021-01-05 |
Family
ID=73963315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202020637218.9U Expired - Fee Related CN212284005U (en) | 2020-04-24 | 2020-04-24 | A reation kettle for azaindole production |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN212284005U (en) |
-
2020
- 2020-04-24 CN CN202020637218.9U patent/CN212284005U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210105 |
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| CF01 | Termination of patent right due to non-payment of annual fee |