CN212111959U - Scanner with two channels of bright field and fluorescence field - Google Patents
Scanner with two channels of bright field and fluorescence field Download PDFInfo
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- CN212111959U CN212111959U CN202020478470.XU CN202020478470U CN212111959U CN 212111959 U CN212111959 U CN 212111959U CN 202020478470 U CN202020478470 U CN 202020478470U CN 212111959 U CN212111959 U CN 212111959U
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Abstract
The utility model discloses a scanner relates to a scanner with bright field and fluorescence field binary channels. The method comprises the following steps: a base; mounting a column; a lens barrel provided with: the bright field reflector is communicated with the bright field camera through the first light outlet channel; the fluorescence reflector is communicated with the fluorescence camera through a second light outlet channel, and a photoelectric sensor is arranged in the fluorescence camera; a fluorescence component is arranged in the second light-emitting channel, a fluoroscope and an objective lens are selected according to requirements, and the fluorescence component and the objective lens are arranged at the bottom of the lens cone; an object stage; spotlight, mount table is provided with: the motor, drive shaft connection mounting bracket are equipped with first erection column on the mounting bracket, are equipped with fluorescence reflector on the first erection column, and the second erection column is equipped with the light screen. And the control device is respectively connected with the photoelectric sensor and the motor. Has the following beneficial effects: the bright field and the fluorescence field are freely switched, so that a bright field scanning image or a fluorescence field scanning image is obtained, and the working efficiency and the image identification accuracy of workers are improved.
Description
Technical Field
The utility model relates to a scanner especially relates to a scanner with bright field and fluorescence field binary channels.
Background
The microscope is an important tool for workers in the whole life science field, and with the improvement of science and technology, the camera and the microscope are ingeniously combined together to form a scanner which is applied to image scanning, the scanner captures images in the microscope through the camera, so that the problem that the workers need to observe an object to be detected in the microscope through visual observation in the past is solved, and the identification accuracy and the identification efficiency of the object to be detected are improved; however, the operator sometimes needs to identify the object to be detected by means of a fluorescence microscope, and particularly, when the circulating tumor cells are identified, the operator needs to compare the object to be detected by means of the combination of a conventional microscope and a fluorescence microscope, at this time, the object to be detected needs to be scanned in a conventional scanner to obtain a conventional scanning image, then the object to be detected is moved into the fluorescence microscope to perform corresponding scanning to obtain a fluorescence scanning image, and then the conventional scanning image and the fluorescence scanning image are combined for comparative analysis.
In order to solve the problems, a scanner with a double channel of a bright field and a fluorescence field is provided, so that the problem that an object to be detected is subjected to bright field scanning and fluorescence field scanning under a microscope is solved, the bright field scanning image or the fluorescence field scanning image is obtained by freely switching the bright field and the fluorescence field, and the efficiency of workers and the image identification accuracy are improved.
SUMMERY OF THE UTILITY MODEL
The utility model discloses a solve above-mentioned problem, present a scanner with bright field and fluorescence field binary channels, include:
the base is arranged at the bottom of the scanner;
the mounting column is arranged on the base and is provided with two mounting holes;
the lens cone is arranged on the mounting column, and is provided with:
the bright field reflector is arranged on one side of the top of the lens cone;
the first light-emitting channel is arranged on one side of the top of the lens cone, which is far away from the bright field reflector;
a bright field camera is arranged on one side, far away from the bright field reflector, of the first light-emitting channel;
the second light-emitting channel is arranged below the first light-emitting channel;
a fluorescence camera is arranged on one side, close to the bright field reflector, of the second light-emitting channel, and a photoelectric sensor is arranged in the fluorescence camera;
the second light-emitting channel is also internally provided with a fluorescent component which is arranged in the second light-emitting channel through an adjusting mechanism;
the first connecting port is arranged on one side of the side wall of the lens cone, which is far away from the second light outlet channel;
the second connecting port is arranged on the side wall of the lens cone and is positioned below the first connecting port;
an objective lens arranged at the bottom of the lens barrel;
the objective table is arranged on the mounting column and is positioned between the second connecting ports of the objective lens;
the spotlight is arranged on the base, and the height of the spotlight is lower than that of the second connecting port;
the mount table sets up keep away from on the erection column lens cone one side, be provided with on the mount table:
a motor arranged on the mounting table,
a driving shaft disposed at a side of the motor adjacent to the lens barrel;
the mounting frame is arranged on the driving shaft, a first mounting column and a second mounting column are arranged on the mounting frame, the first mounting column penetrates through the mounting hole and extends out of the first connecting port, and a fluorescent reflector is arranged on one side, away from the mounting plate, of the first mounting column;
and a light screen is arranged on one side, away from the motor, of the second mounting column.
And the control device is arranged on the base and is respectively connected with the photoelectric sensor and the motor.
Preferably, the fluorescent assembly comprises:
the fluorescent channel is arranged in the second light outlet channel;
and the plurality of fluoroscopes are sequentially and horizontally arranged on one side of the fluorescence channel, which is close to the fluorescence reflector, and a gap is arranged between the fluoroscopes. Preferably, the adjusting mechanism includes:
the adjusting cylinder penetrates through the second light-emitting channel and extends out to two sides, a plurality of clamping blocks are arranged on one side, far away from the fluoroscope, of the adjusting cylinder, and an adjusting channel communicated with the fluorescent channel is arranged on the adjusting cylinder;
the fixture block and the gap are arranged on the same horizontal line;
the positioning barrel is arranged on one side, far away from the fluoroscope, of the adjusting barrel, a positioning channel communicated with the adjusting channel is arranged in the middle of the positioning barrel, and a plurality of clamping grooves corresponding to the clamping blocks are formed in the positioning barrel.
Preferably, the fluoroscope comprises a red fluoroscope, and/or a blue fluoroscope, and/or a green fluoroscope.
Preferably, the light shielding plate is an ultraviolet light shielding plate.
Preferably, the motor is a stepping motor.
Preferably, the drive shaft is a screw drive shaft.
Preferably, the objective lens is provided with a plurality of lenses.
Has the following beneficial effects:
the utility model discloses can carry out bright field scanning and fluorescence field scanning on a scanner, freely switch over in bright field and fluorescence field, realize acquireing bright field scanning image or fluorescence field scanning image, promoted staff's work efficiency and image identification correct rate.
Drawings
FIG. 1 is a schematic diagram of a scanner with dual channels of bright field and fluorescence field according to a preferred embodiment of the present invention;
FIG. 2 is an enlarged view of a portion of the area A in FIG. 1 according to a preferred embodiment of the present invention;
fig. 3 is a schematic structural diagram of a dual-channel switching system for bright field and fluorescence field according to a preferred embodiment of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.
It should be noted that, in the present invention, the embodiments and features of the embodiments may be combined with each other without conflict.
The present invention will be further described with reference to the accompanying drawings and specific embodiments, but the present invention is not limited thereto.
In order to solve the above problems, the present invention provides a scanner with dual channels of bright field and fluorescence field, as shown in fig. 1 to 3, including:
the base 1 is arranged at the bottom of the scanner;
the mounting column 2 is arranged on the base 1, and two mounting holes 21 are formed in the mounting column 2;
a bright field reflector 31 arranged on one side of the top of the lens barrel 3;
a first light-emitting channel 32 arranged on one side of the top of the lens barrel 3 far away from the bright field reflector 31;
a bright field camera 33 is arranged on one side of the first light-emitting channel 32, which is far away from the bright field reflector 31;
a second light-emitting channel 34 disposed below the first light-emitting channel 32;
a fluorescence camera 35 is arranged on one side of the second light-emitting channel 34 close to the bright field reflector 31, and a photoelectric sensor 36 is arranged in the fluorescence camera 35;
a fluorescent component is also arranged in the second light-emitting channel 34, and the fluorescent component is arranged in the second light-emitting channel 34 through an adjusting mechanism;
a first connection port 38 disposed on a side of the sidewall of the lens barrel 3 away from the second light-emitting channel 34;
a second connection port 39 provided on the side wall of the lens barrel 3 and located below the first connection port 38;
an objective lens 4 arranged at the bottom of the lens barrel 3;
an object stage 5 disposed on the mounting post 2 and located between the second connection ports 39 of the objective lens 4;
a spotlight 6 arranged on the base 1, wherein the height of the spotlight 6 is lower than that of the second connecting port 39;
mount table 7, the lens cone 3 one side of keeping away from of setting on erection column 2 is provided with on mount table 7:
a motor 8 arranged on the mounting table 7,
a drive shaft 81 provided on the side of the motor 8 close to the lens barrel 3;
the mounting frame 9 is arranged on the driving shaft 81, a first mounting column 91 and a second mounting column 92 are arranged on the mounting frame 9, the first mounting column 91 penetrates through the mounting hole 21 and extends out to the first connecting port 38, and a fluorescent reflector 93 is arranged on one side, away from the motor 8, of the first mounting column 91;
a light shield 94 is disposed on the side of the second mounting post 92 remote from the motor 8.
And the control device 10 is arranged on the base 1 and is respectively connected with the photoelectric sensor 36 and the motor 8.
Specifically, in this embodiment, in order to solve the problems existing in the prior art, the object to be detected is subjected to bright field scanning and fluorescence field scanning under one microscope, and by freely switching the bright field and the fluorescence field, the bright field scanning image or the fluorescence field scanning image is obtained, so that the efficiency of the worker and the accuracy of image identification are improved. The method comprises the following steps: the base 1 is arranged at the bottom of the scanner, and the base 1 is arranged for stabilizing the scanner; the mounting column 2 is arranged on the base 1, two mounting holes 21 are formed in the mounting column 2, and the mounting column 2 is a main mounting carrier of the scanner; lens cone 3, set up on erection column 2, be provided with on the lens cone 3: a bright field reflector 31 arranged on one side of the top of the lens barrel 3; a first light-emitting channel 32 arranged on one side of the top of the lens barrel 3 far away from the bright field reflector 31;
a bright field camera 33 is arranged on one side of the first light-emitting channel 32, which is far away from the bright field reflector 31, light on the object to be detected passes through the objective 4, then passes through the bright field reflector 31, then passes through the first light-emitting channel 32, and finally reaches the bright field camera 33, and the bright field camera 33 scans the object to be detected to obtain a bright field scanning image; a second light-emitting channel 34 disposed below the first light-emitting channel 32; a fluorescence camera 35 is arranged on one side of the second light-emitting channel 34 close to the bright field reflector 31, a photoelectric sensor 36 is arranged in the fluorescence camera 35, similarly, light on the object to be detected passes through the fluorescence reflector 93 and then passes through the second light-emitting channel 34 to finally reach the fluorescence camera 35, and the fluorescence camera 35 scans the object to be detected to obtain a fluorescence scanning image; the second light-emitting channel 34 is also provided with a fluorescent component, the fluorescent component is arranged in the second light-emitting channel 34 through an adjusting mechanism, and the fluorescent component is used for realizing various fluorescent channels according to actual needs so as to obtain various fluorescent images; the objective lens 4 is arranged at the bottom of the lens barrel 3 and used for aligning and observing an object to be detected; the object stage 5 is arranged on the mounting column 2 and is positioned between the second connecting ports 39 of the objective lens 4, preferably, the height of the object stage 5 can be adjusted up and down, and the object to be detected is focused; the spotlight 6 is arranged on the base 1, the height of the spotlight 6 is lower than that of the second connecting port 39, and the spotlight 6 provides a light source for the object to be detected; mount table 7, the lens cone 3 one side of keeping away from of setting on erection column 2 is provided with on mount table 7: a motor 8 arranged on the mounting table 7, and a driving shaft 81 arranged on one side of the motor 8 close to the lens barrel 3; the mounting frame 9 is arranged on the driving shaft 81, a first mounting column 91 and a second mounting column 92 are arranged on the mounting frame 9, the first mounting column 91 penetrates through the mounting hole 21 and extends out to the first connecting port 38, and a fluorescent reflector 93 is arranged on one side, away from the motor 8, of the first mounting column 91; the side of the second mounting column 92, which is far away from the motor 8, is provided with a light shielding plate 94, the mounting frame is driven by the motor 8 through the driving shaft 81, the fluorescent reflector 93 on the first mounting column 91 is driven to enter the lens barrel 3 through the first connecting port 38, meanwhile, the light shielding plate 94 on the second mounting column 92 also synchronously enters the lens barrel 3 through the second connecting port 39, the original scanner is switched to a fluorescent field under the condition of a bright field, and the fluorescent image scanning for detection is realized.
The control device 10, in order to effectively control the scanner to switch from the bright field to the fluorescent field, the control device 10 is disposed on the base 1, and is respectively connected with the photoelectric sensor 36 and the motor 8, specifically, when the bright field needs to be switched to the fluorescent field, the motor 8 is controlled to rotate by a button on the control device 10, the motor 8 drives the driving shaft 81 to rotate and pushes the mounting frame 9 to move towards the side of the lens barrel 3, the fluorescent reflector 93 and the light shielding plate 94 also move towards the lens barrel 3 synchronously, the photoelectric sensor 36 detects whether there is light transmitted from the fluorescent reflector 93 in real time, when the fluorescent reflector 93 moves to a certain position, the photoelectric sensor 36 receives the intensity of the light reflected from the photoelectric reflector 93 and reaches the set fluorescent intensity, then sends a photoelectric sensing signal to the control device 10, and the control device 10 controls the motor 8 to stop rotating after receiving the photoelectric sensing signal, switching the scanner from bright to fluorescent field is accomplished.
In a preferred embodiment of the present invention, as shown in fig. 2, the fluorescent assembly comprises:
a fluorescent channel 41 disposed in the second light exit channel 39;
and the plurality of fluoroscopes 42 are sequentially and horizontally arranged on one side, close to the fluorescent reflector 93, of the fluorescent channel 41, and a gap 47 is formed between the fluoroscopes 42.
Specifically, in this embodiment, the fluorescence channel 41 is disposed in the second light-emitting channel 39, and is configured to enable light reflected from the fluorescence reflector 93 to smoothly reach the fluorescence camera, the plurality of fluorescence mirrors 42 are sequentially horizontally disposed on one side, close to the fluorescence reflector 93, of the fluorescence channel 41, and a plurality of fluorescence mirrors 42 are disposed, so that the corresponding fluorescence mirrors can be selected as needed, a gap 47 is disposed between the fluorescence mirrors 42, and the gap is disposed in the fluorescence mirrors 42, so that the fluorescence image scanned by the fluorescence camera 35 cannot be interfered when the fluorescence mirrors are adjusted by the adjusting mechanism.
In a preferred embodiment of the present invention, as shown in fig. 2, the adjusting mechanism comprises:
the adjusting cylinder 43 penetrates through the second light-emitting channel 39 and extends out to two sides, a plurality of clamping blocks 44 are arranged on one side, far away from the fluoroscope 42, of the adjusting cylinder 43, and an adjusting channel 48 communicated with the fluorescent channel 41 is arranged on the adjusting cylinder 43;
the fixture block 44 and the gap 47 are arranged on the same horizontal line;
the positioning tube 45 is arranged on one side, far away from the fluoroscope 42, of the adjusting tube 43, a positioning channel 49 communicated with the adjusting channel 48 is arranged in the middle of the positioning tube 45, and a plurality of clamping grooves 46 corresponding to the clamping blocks 44 are arranged on the positioning tube 45.
Specifically, in the present embodiment, a fixture block 44 is disposed on the adjusting cylinder 43, and the position of the fluorescence assembly is adjusted up and down by the adjusting cylinder 43, so as to achieve the desired fluorescence lens 42. Light passes from the fluorescence mirror 93 through the selected fluoroscope 42 and into the fluorescence channel 41, then into the adjustment channel 48, and finally into the fluorescence camera through the positioning channel 49, completing the switching of the fluoroscope 42.
In the preferred embodiment of the present invention, fluoroscope 42 comprises a red fluoroscope, and/or a blue fluoroscope, and/or a green fluoroscope.
In the preferred embodiment of the present invention, the light shield 94 is an ultraviolet light shield.
Specifically, in the present embodiment, after the light shielding plate 94 is set as an ultraviolet light shielding plate, the ultraviolet light shielding plate only allows ultraviolet light to pass through, and ultraviolet light in the spotlight reaches the object stage 5 through the ultraviolet light shielding plate, so as to provide a light source for the object to be detected on the object stage 5, and it is not necessary to provide a light source for the object to be detected.
Specifically, in the present embodiment, the fluoroscope 42 includes, but is not limited to, a red fluoroscope, a blue fluoroscope, and a green fluoroscope, and can be set according to actual needs.
In the preferred embodiment of the present invention, the motor 8 is a stepping motor.
Specifically, in this embodiment, the motor 8 is a stepping motor, the technology of the stepping motor is mature, and the control position is accurate.
In the preferred embodiment of the present invention, the driving shaft 81 is a screw driving shaft.
Specifically, in this embodiment, the driving shaft 81 is a screw driving shaft, so that the screw is highly practical and is easy to maintain.
In the preferred embodiment of the present invention, the objective lens 4 is provided with a plurality of lenses 48.
Specifically, in this embodiment, the objective lens 4 is provided with a plurality of lenses 48, and the lenses with different multiples can be selected as required.
The above description is only an example of the preferred embodiment of the present invention, and not intended to limit the scope of the present invention, and those skilled in the art should be able to realize the equivalent alternatives and obvious variations of the present invention.
Claims (8)
1. A scanner having dual channels, bright and fluorescent, comprising:
the base is arranged at the bottom of the scanner;
the mounting column is arranged on the base and is provided with two mounting holes;
the lens cone is arranged on the mounting column, and is provided with:
the bright field reflector is arranged on one side of the top of the lens cone;
the first light-emitting channel is arranged on one side of the top of the lens cone, which is far away from the bright field reflector; a bright field camera is arranged on one side, far away from the bright field reflector, of the first light-emitting channel;
the second light-emitting channel is arranged below the first light-emitting channel;
a fluorescence camera is arranged on one side, close to the bright field reflector, of the second light-emitting channel, and a photoelectric sensor is arranged in the fluorescence camera;
a fluorescent component is also arranged in the second light-emitting channel and is arranged in the second light-emitting channel through an adjusting mechanism;
the first connecting port is arranged on one side of the side wall of the lens cone, which is far away from the second light outlet channel;
the second connecting port is arranged on the side wall of the lens cone and is positioned below the first connecting port;
an objective lens arranged at the bottom of the lens barrel;
the objective table is arranged on the mounting column and is positioned between the second connecting ports of the objective lens;
the spotlight is arranged on the base, and the height of the spotlight is lower than that of the second connecting port;
the mount table sets up keep away from on the erection column lens cone one side, be provided with on the mount table:
a motor arranged on the mounting table,
a driving shaft disposed at a side of the motor adjacent to the lens barrel;
the mounting frame is arranged on the driving shaft, a first mounting column and a second mounting column are arranged on the mounting frame, the first mounting column penetrates through the mounting hole and extends out of the first connecting port, and a fluorescent reflector is arranged on one side, away from the motor, of the first mounting column;
a shading plate is arranged on one side, away from the motor, of the second mounting column;
and the control device is arranged on the base and is respectively connected with the photoelectric sensor and the motor.
2. The scanner of claim 1, wherein the fluorescence assembly comprises:
the fluorescent channel is arranged in the second light outlet channel;
the plurality of fluoroscopes are sequentially and horizontally arranged on one side, close to the fluorescent reflector, of the fluorescent channel; a gap is arranged between the fluoroscopes.
3. The scanner of claim 2, wherein the adjustment mechanism comprises:
the adjusting cylinder penetrates through the second light-emitting channel and extends out to two sides, a plurality of clamping blocks are arranged on one side, far away from the fluoroscope, of the adjusting cylinder, and an adjusting channel communicated with the fluorescent channel is arranged on the adjusting cylinder;
the fixture block and the gap are arranged on the same horizontal line;
the positioning barrel is arranged on one side, far away from the fluoroscope, of the adjusting barrel, a positioning channel communicated with the adjusting channel is arranged in the middle of the positioning barrel, and a plurality of clamping grooves corresponding to the clamping blocks are formed in the positioning barrel.
4. A scanner according to claim 2 wherein the fluoroscope comprises a red fluoroscope, and/or a blue fluoroscope, and/or a green fluoroscope.
5. The scanner of claim 1, wherein the shutter is an ultraviolet shutter.
6. The scanner of claim 1, wherein the motor is a stepper motor.
7. The scanner of claim 1, wherein the drive shaft is a lead screw drive shaft.
8. The scanner of claim 1, wherein the objective lens has a plurality of lenses disposed thereon.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020478470.XU CN212111959U (en) | 2020-04-03 | 2020-04-03 | Scanner with two channels of bright field and fluorescence field |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020478470.XU CN212111959U (en) | 2020-04-03 | 2020-04-03 | Scanner with two channels of bright field and fluorescence field |
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| Publication Number | Publication Date |
|---|---|
| CN212111959U true CN212111959U (en) | 2020-12-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202020478470.XU Active CN212111959U (en) | 2020-04-03 | 2020-04-03 | Scanner with two channels of bright field and fluorescence field |
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| Country | Link |
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| CN (1) | CN212111959U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115202027A (en) * | 2022-08-26 | 2022-10-18 | 徕卡显微系统科技(苏州)有限公司 | Dual-camera switching device, switching method and microscope system |
-
2020
- 2020-04-03 CN CN202020478470.XU patent/CN212111959U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115202027A (en) * | 2022-08-26 | 2022-10-18 | 徕卡显微系统科技(苏州)有限公司 | Dual-camera switching device, switching method and microscope system |
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