CN212059805U - Sample analysis system - Google Patents
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- CN212059805U CN212059805U CN201921994354.7U CN201921994354U CN212059805U CN 212059805 U CN212059805 U CN 212059805U CN 201921994354 U CN201921994354 U CN 201921994354U CN 212059805 U CN212059805 U CN 212059805U
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Abstract
The utility model relates to a sample analysis system, including blood sedimentation analyzer, blood cell analyzer, transmission device, sample identification equipment and dispatch controlgear, wherein, be provided with the transmission channel that is used for transporting the sample container that loads with the sample in the transmission device, be provided with two at least sample detection positions in the direction of transmission along transmission channel; the blood sedimentation analyzer and the blood cell analyzer respectively correspond to a sample detection position; the sample identification device is used for scanning the sample containers conveyed on the conveying channel to obtain the identity information of the samples in the sample containers and at least one mode to be detected; the dispatching control equipment is electrically connected with the sample identification equipment and the transmission mechanism respectively. The sample analysis system can flexibly convey the sample container loaded with the sample to a corresponding analyzer for corresponding detection according to the to-be-detected mode of the sample, so that the measurement speed and the measurement efficiency are improved.
Description
Technical Field
The utility model relates to a medical diagnostic equipment field especially relates to a sample analysis system.
Background
The Erythrocyte Sedimentation Rate (ESR) test has long and widespread clinical application, which refers to the sedimentation rate of erythrocytes within 1 hour, and is a reliable and indirect acute phase inflammatory response factor. In infectious diseases, acute and chronic inflammatory reactions, ESR values often rise. ESR is also widely applied to the course of rheumatism and connective tissue diseases and the process of treatment monitoring. In addition, ESR is also often increased in cancer and hodgkin's disease.
Blood routine is one of three routine examinations, and is also one of the commonly used auxiliary examinations for doctors to diagnose the disease. The doctor can judge the disease by observing the change of the number of blood cells and the morphological distribution. Therefore, ESR can be tested in conjunction with blood routine, i.e., a blood sample is taken once, to perform both tests. However, in the conventional ESR and blood conventional combined detection, a pipeline channel is led out from a blood sample, an ESR detector and a blood conventional measuring instrument are sequentially arranged on the pipeline channel, and a pipeline corresponding to the ESR adopts a light-transmitting capillary vessel, so that the ESR detector and the blood conventional measuring instrument sequentially perform ESR and blood conventional measurement on the blood sample transmitted in the pipeline channel. In the scheme of the combined detection, the ESR detector and the blood conventional measuring instrument are arranged in series, and then the ESR detector and the blood conventional measuring instrument sequentially detect the same blood sample transmitted by the pipeline channel.
However, blood is a routine test item, basically all samples entering the clinical laboratory need to be tested, and ESR is only a certain percentage of the inflammation test item. Therefore, during the conventional serial detection of ESR and blood, no matter whether the ESR is detected in the blood sample or not, the blood sample can flow through the ESR detector through the pipeline channel during each measurement, so that the measurement time of the blood routine of the blood sample which only needs the blood routine measurement is increased, and the measurement speed of the clinical blood routine measurement is greatly reduced.
SUMMERY OF THE UTILITY MODEL
In order to solve the technical problem or at least partially solve the technical problem, the utility model provides a sample analysis system adopts the assembly line mode, and blood sedimentation analyzer and blood cell analyzer do not independent work on the assembly line respectively, can improve the detection efficiency of ESR and blood conventionality.
The embodiment of the application provides a sample analysis system, includes: a blood sedimentation analyzer, a blood cell analyzer, a transport mechanism, a sample identification device, and a dispatch control device, wherein,
the conveying mechanism is internally provided with a conveying channel for conveying a sample container loaded with a sample, and at least two sample detection positions are arranged in the conveying direction along the conveying channel;
the blood sedimentation analyzer and the blood cell analyzer respectively correspond to one sample detection position;
the erythrocyte sedimentation rate detection device is used for detecting the erythrocyte sedimentation rate of the sample in the sample container conveyed to the sample detection position corresponding to the erythrocyte sedimentation rate detection device by the conveying mechanism, enabling the sample to flow in the detection pipeline, stopping the sample when the sample flows to the detection area in the detection pipeline, irradiating the sample in the detection area with light and detecting the absorption or scattering degree of the sample in the detection area to the light;
the blood cell analyzer is used for carrying out routine blood detection on the sample in the sample container conveyed to the sample detection position corresponding to the blood cell analyzer by the conveying mechanism;
the sample identification device is used for scanning the sample container conveyed on the conveying channel to obtain the identity information of the sample in the sample container and at least one to-be-detected mode corresponding to the identity information;
the dispatching control device is respectively electrically connected with the sample identification device and the transmission mechanism, and is used for receiving the identity information sent by the sample identification device and at least one to-be-detected mode corresponding to the identity information, and controlling the transmission mechanism to convey the sample container to a sample detection position corresponding to the at least one to-be-detected mode, so that the corresponding detection of the sample in the sample container is performed by the erythrocyte analyzer or the erythrocyte analyzer corresponding to the sample detection position.
Optionally, the blood cell analyzer is located in front of the sedimentation analyzer in the transport direction along the transport channel.
Optionally, the scheduling control device is configured to control the transport mechanism to transport the sample container to a sample detection position corresponding to the blood cell analyzer first and then to a sample detection position corresponding to the blood sedimentation analyzer when the at least one to-be-detected mode of the sample container includes a erythrocyte sedimentation rate detection mode and a blood routine detection mode.
Optionally, the at least two sample detection sites are disposed in the transport path, and the sample containers transported in the transport path sequentially pass through the at least two sample detection sites along the transport direction of the transport path.
Optionally, the conveying mechanism further includes at least two feeding mechanisms, wherein the at least two feeding mechanisms are connected to the conveying channel, each sample detection position corresponds to one feeding mechanism, a detection channel is disposed in the feeding mechanism, and each sample detection position is located in the detection channel of the corresponding feeding mechanism;
the feeding mechanism is used for transferring the sample containers in the transmission channels to the corresponding detection channels and transferring the sample containers in the corresponding detection channels to the transmission channels.
Optionally, each of the feed mechanisms further comprises:
a transmission mechanism formed with a detection channel;
the loading buffer area is positioned between the input end of the detection channel and the transmission channel and communicates the detection channel with the transmission channel, so that a sample container on the transmission channel can enter the loading buffer area;
and the loading mechanism is positioned in the loading buffer area and used for transferring the sample container in the loading buffer area to the input end of the detection channel.
Optionally, the feeding mechanism further comprises:
the unloading buffer area is positioned between the output end of the detection channel and the transmission channel and communicates the detection channel with the transmission channel, so that a sample container in the output end of the detection channel can enter the unloading buffer area;
and the unloading mechanism is positioned in the unloading buffer area and used for transferring the sample container in the unloading buffer area to the conveying channel.
Optionally, the blood sedimentation analyzer includes a power device connected to the detection line, and the power device is configured to drive the sample to flow into the detection line, and stop and keep the sample after flowing to the detection area of the detection line, so as to irradiate the sample in the detection area with light.
Optionally, the sample analysis system further comprises: and the display is used for receiving the detection result sent by the blood sedimentation analyzer and/or the blood corpuscle analyzer and displaying the detection result in a display interface.
Optionally, the sample analysis system further comprises: and the data storage device is used for receiving and storing the detection result sent by the blood sedimentation analyzer and/or the blood corpuscle analyzer.
Optionally, the sample analysis system further comprises a slide dyeing machine and/or a saccharification instrument, and each of the slide dyeing machine and the saccharification instrument corresponds to one of the sample detection positions.
In the sample analysis system provided by the embodiment of the application, a transmission channel for conveying a sample container loaded with a sample is arranged in the transmission mechanism; at least two sample detection positions are arranged in the transmission direction along the transmission channel, and a blood sedimentation analyzer and a blood corpuscle analyzer respectively correspond to one sample detection position; the sample identification equipment scans the sample container conveyed on the conveying channel to obtain the identity information of the sample in the sample container and at least one to-be-detected mode corresponding to the identity information; and finally, the scheduling control equipment receives the identity information sent by the sample identification equipment and at least one to-be-detected mode corresponding to the identity information, and controls the transmission mechanism to convey the sample container to a sample detection position corresponding to the at least one to-be-detected mode, so that the corresponding detection of the sample in the sample container is carried out by the blood sedimentation analyzer or the blood cell analyzer corresponding to the sample detection position.
Because the blood cell analyzer and the blood sedimentation analyzer are separately and independently arranged in the sample analysis system, if the same sample needs blood sedimentation analysis and blood routine detection, the sample container loaded with the sample can be controlled by the transmission mechanism to be respectively transported to the blood sedimentation analyzer and the blood cell analyzer for corresponding analysis; if only routine testing of blood is required and no blood sedimentation analysis is required, the sample container need not be transported to an on-blood sedimentation analyzer. Compared with the prior art that whether the blood sample is subjected to the blood sedimentation analysis or not needs to flow through the blood sedimentation detector, the sample analysis system can flexibly convey the sample container to be detected to the required analyzer according to the mode to be detected required by the sample container for corresponding analysis, so that the measurement speed and the measurement efficiency are improved.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the invention and together with the description, serve to explain the principles of the invention.
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without inventive labor.
FIG. 1 is a schematic view of a first embodiment of a sample analysis system provided herein;
FIG. 2 is a schematic view of a second embodiment of a sample analysis system provided herein;
FIG. 3 is a schematic structural diagram of a feeding mechanism provided in an embodiment of the present application;
FIG. 4 is a schematic structural diagram of a loading mechanism according to an embodiment of the present disclosure;
fig. 5 is a schematic structural diagram of a load buffer according to an embodiment of the present disclosure;
FIG. 6 is a schematic structural diagram of a sample rack provided in an embodiment of the present application;
fig. 7 is a schematic diagram of another sample analysis system provided in an embodiment of the present application.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
Example 1
Fig. 1 is a schematic structural diagram of a first embodiment of a sample analysis system provided by the present invention, which includes: a blood cell analyzer 10, a blood sedimentation analyzer 20, a sample identification device 30, a dispatch control device 40, and a transport mechanism 50.
In the embodiment of the present application, the hematology analyzer 10 and the sedimentation analyzer 20 each have an internal controller therein, i.e., the hematology analyzer 10 and the sedimentation analyzer 20 may be complete independent modules. In the present embodiment, the hematology analyzer 10 and the sedimentation analyzer 20 may be combined in the sample analysis system in a modular fashion.
The transport mechanism 50 is provided with a transport path for transporting a sample container loaded with a sample (or a sample rack loaded with a sample container), and at least two sample detection sites 55 and 56 (areas indicated by oval broken lines in the drawing) are provided along a transport direction X of the transport path, and a direction indicated by an arrow in fig. 1 is the transport direction X.
Referring to fig. 1, the transmission mechanism 50 includes a plurality of transmission segments connected to each other, as shown in fig. 1, there are four transmission segments, 51, 52, 53, and 54, wherein the transmission segments (51, 52, 53, and 54) are connected end to end in sequence, and adjacent transmission segments are connected to each other, or a gap that does not affect the transmission of the sample container or the sample rack is provided between adjacent transmission segments. A transport channel for transporting sample containers or sample racks may be formed between the transport sections.
In a specific application, each transfer section (51, 52, 53, 54) can adopt any one or more combination of a chain mechanism, a crawler mechanism, a belt mechanism, a roller mechanism and a track mechanism, and the plurality of transfer sections generally adopt the same type of mechanism for maintenance and maintenance.
In the embodiment of the present application, the transport sections (51, 52, 53, 54) are only required to complete the transfer of the sample container, and the shape of the transport channel is not limited, for example: the transmission channel can be a linear type, a broken line with a certain angle or an arc line with a certain radian, and even an irregular shape.
In the embodiment of the present application, the transmission channel may be a planar channel, for example: the upper surface of a belt of the belt type mechanism is directly used as a transmission channel; in addition, the transport channel may also be a semi-enclosed channel, considering that the sample container may fall or be twisted in position when being transported, for example: the baffle plates are arranged on two sides of the belt type mechanism, and the top of each baffle plate is not sealed, so that a semi-enclosed transmission channel is formed in an area enclosed by the baffle plates, and the sample container is restrained by the baffle plates and cannot fall or be twisted in position. In addition, considering that the sample container may be placed in a mess after being manually taken when the sample container is moved, the transmission channel may also be a totally enclosed channel, such as: the baffle plates are arranged on the two sides and the top of the belt type mechanism, so that the problem of manual intervention can be avoided when the sample container is transferred in the transmission channel.
In the embodiment of the application in which the transport path serves as a path for transporting sample containers or sample racks, the transport mechanism 50 may, in operation, move the sample containers or sample racks to a position on the transport path at which each of the sample testing positions 55, 56 is located.
The blood sedimentation analyzer 20 and the blood cell analyzer 10 each correspond to one of the sample detection sites, as shown in fig. 1, the blood sedimentation analyzer 20 corresponds to the sample detection site 55, and the blood cell analyzer 10 corresponds to the sample detection site 56. In the embodiment of the present application, the sedimentation analyzer 20 corresponds to the sample detection position 55, which means that the sedimentation analyzer 20 corresponds to the position of the sample detection position 55 in the transmission channel, the sedimentation analyzer 20 can contact with the transmission mechanism 50, and an interval can also be provided between the sedimentation analyzer and the transmission mechanism 50, and in any way, the sedimentation analyzer 20 can detect the erythrocyte sedimentation rate of the sample in the sample container on the sample detection position 55. In particular applications, the sedimentation analyzer 20 may be positioned on one side of the transport path where the sample detection site 55 is located, with the sample detection site 55 located in the transport path, or the sedimentation analyzer 20 may be positioned above the transport path where the sample detection site 55 is located, such as with the sedimentation analyzer 20 straddling the transport path with the sample detection site 55 located in the transport path. The arrangement between the blood cell analyzer 10 and the transfer mechanism 50 can be seen from the description of the blood sedimentation analyzer 20 and the transfer mechanism 50, and will not be described herein.
The sedimentation analyzer 20 is used for performing erythrocyte sedimentation rate detection of a sample in a sample container carried by the transport mechanism 50 to a sample detection site 55 corresponding thereto by causing the sample to flow in a detection line, stopping the movement of the sample when the sample flows to a detection area in the detection line, irradiating light to the sample in the detection area, and detecting the degree of absorption or scattering of the light by the sample in the detection area. Since the scattering or transmission of light impinging on the blood sample changes during the process of aggregating the red blood cells in the blood sample (forming rouleaux), the degree to which the blood sample scatters or absorbs light can be detected by detecting the amount of transmitted or scattered light after receiving the illuminated blood sample, thereby measuring the erythrocyte sedimentation rate.
The blood cell analyzer 10 is used for performing routine blood testing on a sample in a sample container transported by the transport mechanism 50 to a sample testing position corresponding thereto. In an embodiment of the present application, the blood cell analyzer includes a blood routine detecting cell for providing a detecting place for a sample in a sample container, and a blood routine detecting device for performing blood routine detection on the sample in the blood routine detecting cell.
It will be appreciated by those skilled in the art that the blood routine detecting means may be an optical detecting portion or an impedance detecting portion. When the blood routine detection module performs blood routine detection on a blood sample, the blood sample and a corresponding reaction reagent may be added into a blood routine detection pool, and the blood sample in the blood routine detection pool is measured by a blood routine detection device to obtain at least one blood routine parameter, where the blood routine parameter may include at least one or more combinations of WBC (White blood cell) five classification results, WBC count and morphological parameters, HGB (Hemoglobin) function measurement, RBC (Red blood cell) and PLT (platelet) count and morphological parameters, and in an actual blood routine detection process, the blood routine detection items may be increased or decreased as needed, which is not limited herein.
Referring to fig. 1, the sample recognition device 30 is configured to scan the label of the sample container transported on the transport path to obtain the identity information of the sample in the sample container and at least one to-be-detected pattern corresponding to the identity information. In a particular application, the sample identification device 30 may be located on one side of the transport channel as shown in FIG. 1. In addition, the sample recognition device 30 may also be provided in other analyzers, such as: the sample recognition device 30 is disposed in the first analyzer in the transport direction in the transport path, and as shown in fig. 1, the sample recognition device 30 may be disposed in the blood cell analyzer 10.
In this embodiment, the identity information of the sample may be an identification identifier, for example: character marks such as Chinese characters, numeric strings, letter strings and the like, and graphic marks such as bar codes, two-dimensional codes and the like can also be used. In one case, both the identity information and the at least one pattern to be detected corresponding to the identity information may be provided on the sample container, for example: the bar code or the two-dimensional code not only contains identity information, but also contains at least one mode to be detected corresponding to the identity information, so that the sample identification equipment can directly read the identity information and the mode to be detected from the sample container. In another case, only the identity information may be set on the sample container, and the at least one to-be-detected pattern corresponding to the identity information is stored in a storage medium (the storage medium may be located in the scheduling control device 40, or the storage medium is independent of the scheduling control device 40, and the scheduling control device 40 is connected to the storage medium) in a corresponding relationship, so that after the sample identification device 30 acquires the identity information, the at least one to-be-detected pattern corresponding to the identity information may be read from the storage medium according to the corresponding relationship.
The schedule control apparatus 40 is electrically connected to the sample recognition apparatus 30 and the transport mechanism 50, respectively. In one embodiment, the sample identification device 30 may include an image collector, such as a camera or scanner, for example. The dispatch control device 40 is connected to the sample recognition device 30 through a cable, and is configured to receive the identity information sent by the sample recognition device 30 and at least one to-be-detected pattern corresponding to the identity information.
In the embodiment of the present application, the scheduling control device 40 may be a single chip, a computer, a programmable controller, or other devices with computing capability. The scheduling control device 40 serves as a control module of the transport mechanism 50, and is used for controlling the motion of the transport mechanism 50 to drive the sample container in the transport channel to move.
In the sample analysis system provided in the embodiment of the present application, the blood cell analyzer 10 and the blood sedimentation analyzer 20 are provided independently of each other, and the transport mechanism 50 and the sample identification device 30 are provided, and the dispatch control device 40 controls the transport mechanism 50 to transport the sample container loaded with the sample to be tested to the blood cell analyzer 10 and/or the blood sedimentation analyzer 20, respectively, according to the information of the sample identification device 30. That is to say, the sample analysis system can flexibly control the transmission mechanism 50 to convey the sample container to the analyzer corresponding to the mode to be detected for corresponding analysis according to the mode to be detected required by the sample container, so that the measurement speed and the measurement efficiency are improved.
Example 2
In the embodiment of the present application, the arrangement of the blood cell analyzer 10 and the erythrocyte sedimentation analyzer 20 in the transport direction of the transport channel is a layout in advance, as shown in fig. 1, the blood cell analyzer 10 is located in front of the erythrocyte sedimentation analyzer 20 in the transport direction along the transport channel, and in this layout, when the sample in the sample container requires the erythrocyte sedimentation rate detection and the blood routine detection at the same time, the blood routine can be detected first, and then the erythrocyte sedimentation rate can be detected.
In other embodiments of the present application, the hematology analyzer 10 may also be located behind the sedimentation analyzer 20 in the transport direction along the transport channel.
The blood cell analyzer will be described below with reference to fig. 1, which is located in front of the blood sedimentation analyzer.
In fig. 1, if the at least one to-be-detected mode in which the sample identification device 30 obtains the sample in the sample container includes the erythrocyte sedimentation rate detection mode and the blood routine detection mode, the scheduling control device 40 first controls the transport mechanism 50 to transport the sample container to the sample detection position 56 corresponding to the blood cell analyzer 10, and waits for the blood cell analyzer 10 to perform the blood routine detection on the sample in the sample container staying at the sample detection position 56 while staying at the sample detection position 56. The dispatch control device 40 then controls the transport mechanism 50 to transport the sample container to the sample testing location 55 corresponding to the blood sedimentation analyzer 20 and stop so that the blood sedimentation analyzer 20 performs the erythrocyte sedimentation rate test on the sample in the sample container at the sample testing location 55.
In the embodiment of the present application, the scheduling control device 40 may also be electrically connected to the blood cell analyzer 10 and the blood sedimentation analyzer 20, respectively, for receiving the detection status sent by the blood cell analyzer 10 or the blood sedimentation analyzer 20, for example: in fig. 1, when the blood cell analyzer 10 starts performing a blood routine test, test start state information is transmitted to the schedule control apparatus 40, and after the blood cell analyzer 10 completes the blood routine test, test end state information is transmitted to the schedule control apparatus 40.
The schedule control apparatus 40, upon receiving the detection end state information transmitted from the blood cell analyzer 10, controls the transport mechanism 50 to move the sample container from the sample detection position 56 to the sample detection position 55 and stop the container.
In addition, in fig. 1, at least two sample detection sites (55, 56) are provided in the transport channel, and in particular, both the hematology analyzer 10 and the sedimentation analyzer 20 straddle the transport channel such that the sample detection sites are located in the transport channel. Meanwhile, the sample container conveyed in the conveying channel sequentially passes through the at least two sample detection positions along the conveying direction of the conveying channel.
Example 3
In an embodiment of the present application, the sample analysis system may further include: at least one display. The display can be electrically connected with any one or two of the blood sedimentation analyzer and the blood corpuscle analyzer, and the display is used for receiving and displaying the detection result in the blood sedimentation analyzer and/or the blood corpuscle analyzer.
In displaying the detection results, the detection results of the blood cell analyzer and the blood sedimentation analyzer may be displayed separately, but considering that the conventional blood detection result of the sample in the same sample container may have a correlation with the erythrocyte sedimentation rate, the conventional blood detection result and the erythrocyte sedimentation rate may be displayed in combination, for example: if the sample in the sample container is subjected to the conventional blood detection of the hematology analyzer, the conventional blood detection result is displayed on the display, and after the sample in the sample container is subjected to the blood sedimentation detection of the blood sedimentation analyzer, the conventional blood detection result and the erythrocyte sedimentation rate are combined and displayed on the display.
In addition, in order to conveniently store the data of the detection result, in this embodiment, the sample analysis system may further include: at least one data storage device which can be electrically connected with the blood sedimentation analyzer and the blood corpuscle analyzer and is used for receiving and storing the detection result sent by the blood sedimentation analyzer and/or the blood corpuscle analyzer.
Example 4
Fig. 2 is a schematic diagram of a second embodiment of a sample analysis system according to an embodiment of the present application.
In the present embodiment, the transport mechanism 50 further includes at least two feeding mechanisms, as shown in fig. 2, which includes: and feeding mechanisms 61, 62 (shown by large oval dashed boxes in the figure), wherein each feeding mechanism is connected with the transmission channel, and each sample detection position corresponds to one feeding mechanism. In addition, a detection channel is arranged in the feeding mechanism, and each sample detection position is positioned in the corresponding detection channel of the feeding mechanism.
The feeding mechanism is used for transferring the sample containers in the transmission channels to the corresponding detection channels and transferring the sample containers in the corresponding detection channels to the transmission channels. Referring to fig. 2, the sample detection sites 55, 56 are no longer located within the transport channel, but rather are located on the side outside the transport channel. In the embodiment of the present application, the sample detection site is provided in the detection channel of the corresponding feeding mechanism.
Referring to fig. 3, a schematic structural diagram of a feeding mechanism provided in an embodiment of the present application is shown. As shown in fig. 3, the feeding mechanism 61 corresponding to the blood sedimentation analyzer 20 may include: drive mechanism 421, load buffer 422 and loading mechanism 423, wherein:
the transmission mechanism 421 may be any one or a combination of a chain mechanism, a crawler mechanism, a belt mechanism, a roller mechanism, and a track mechanism, and if a plurality of combinations are adopted, the transmission mechanism 421 may be provided with a plurality of sections of mechanisms of different types. In the embodiment of the present application, a detection channel is formed in the transmission mechanism 421, and it can be seen from the figure that the detection channel is located outside the transmission channel and is spaced from the transmission channel.
In addition, the loading buffer 422 is located between the input end of the detection channel and the transmission channel, and the detection channel is communicated with the transmission channel, so that the sample container or sample rack on the transmission channel can enter the loading buffer 422. The loading buffer 422 is provided to take into account that if the number of sample containers transferred to the feeding mechanism through the transmission channel is large, a certain time is consumed for the sedimentation analyzer to complete the detection of each sample container, and if all the sample containers on the transmission channel are transferred to the sedimentation analyzer, the normal analysis and detection of the sedimentation rate of red blood cells are affected. The loading buffer 422 may be configured to buffer the sample containers or sample racks transferred on the transport path in the area, and then sequentially transfer the buffered sample containers or sample racks in the area to the detection path according to the detection speed of the blood sedimentation analyzer.
As shown in fig. 3, the loading mechanism 423 is located in the loading buffer 422, and the loading mechanism 423 is used for transferring the sample container or the sample rack loaded in the loading buffer 422 to the input end of the detection channel.
In addition, the loading mechanism 423 may also be used to move sample containers or sample racks on the transport path to the loading buffer 422. The loading mechanism 423 moves the sample container or rack on the transport path out of the transport path as the sample container or rack is moved to the home position shown by the box with a dashed square in fig. 3.
In the present embodiment, the loading mechanism 423 has two functions, namely, unloading the sample container or the sample rack from the transport lane and transferring the sample container or the sample rack loaded in the buffer area to the detection lane. In the embodiment of the present application, the feeding mechanism as a part of the transport mechanism 50 may also be under the schedule control of the schedule control apparatus 40.
In the embodiment of the present application, as shown in fig. 4, the loading mechanism 423 may include: a holder 131, a pusher 132, and a pusher driving device 133, the holder 131 being disposed between the transport path and the detection path for supporting the loading mechanism 423; the pushing claw 132 is disposed on the bracket 131, and is used to drive the sample container or the sample rack stored in the loading buffer 422 to slide toward the detection channel or the transmission channel, and if a sample rack is adopted, the sample container can be placed on the sample rack. So that the sample rack is transmitted between the transmission channel and the detection channel; the pawl driving device 133 is disposed on the bracket 131 for driving the pawl 132 to perform the above-mentioned movement process.
In an alternative embodiment, as shown in fig. 5, the loading buffer 422 in the sample analysis system according to the embodiment of the present application includes: the panel 141 is used for carrying the sample rack, and the panel 141 is provided with a long hole 142 extending from the transmission channel to the detection channel. The pawl driving device 133 includes: the device comprises a horizontal pushing assembly 1331, a pusher claw mounting seat 1332 and a lifting assembly 1333, wherein the horizontal pushing assembly 1331 is arranged on the bracket 131 and can horizontally move relative to the bracket 131; the pusher jaw mounting seat 1332 is linked with the horizontal pushing assembly 1331, and the horizontal pushing assembly 1331 drives the pusher jaw mounting seat 1332 to horizontally move between the detection channel and the transmission channel; the lifting assembly 1333 is disposed on the pusher mounting base 1332, the pusher 132 is disposed on the lifting assembly 1333, the lifting assembly 1333 drives the pusher 132 to ascend, so that the pusher 132 at least partially penetrates through the long hole 142 on the panel 141 and is matched with the bottom of the sample rack, and the horizontal pushing assembly 13231 can drive the pusher mounting base 1332 to move horizontally, so that the pusher 132 drives the sample rack to slide toward the detection channel or the transmission channel on the panel 141. Alternatively, in order to position the moving position of the pusher jaw 132, a position sensor 135 is respectively disposed at two ends of the bracket 131 near the detection channel and the transmission channel, and the position sensor 135 can cooperate with the pusher jaw mounting seat 1332 or the pusher jaw 132 to enable the dispatch control device to obtain the moving position of the pusher jaw 132. Position sensor 135 is preferably the opto-coupler, is provided with the optical coupling piece on pusher dog mount 1332, and when pusher dog mount 1332 moved to being close to detection channel or transmission channel, the optical coupling piece acted on with the opto-coupler and made the opto-coupler send inductive signal to make the position that dispatch controlgear can judge pusher dog 132.
In an alternative embodiment of the present application, the horizontal pushing assembly 1331 may be a motor synchronous belt driving mechanism, and a motor is used to drive a synchronous belt to rotate, so as to drive the pushing claw mounting seat 1332 to perform a horizontal movement. Of course, the horizontal pushing assembly 1331 may also be a linear motor, and the primary of the linear motor drives the pusher jaw mounting 1332 to perform a horizontal linear motion. In order to ensure stable operation of the claw mounting 1332, a linear guide may be mounted on the bracket 131, and the claw mounting 1332 may be slidably mounted on the linear guide. The lifting assembly 1333 may be a lifting cylinder, the cylinder body of the lifting cylinder is fixed on the pusher dog mounting seat 1332, the pusher dog 132 is fixedly connected to the piston rod of the lifting cylinder, and the piston rod of the lifting cylinder is controlled to drive the pusher dog 132 to move up and down.
As shown in fig. 6, the sample containers are typically transported through the sample rack. Bottom slots 151 are formed in the bottom of the sample rack 15 at intervals, and when the push claws 132 extend upwards from the long holes 142 on the panel 141, the push claws can be inserted into the bottom slots 151 in the bottom of the sample rack 15, so that the sample rack 15 is driven to move synchronously. As can be seen from the figure, the sample rack 15 is provided with a plurality of sample container holders 152, and sample containers can be placed on the sample container holders 152.
In this embodiment, taking the sample recognition device 30 integrated in the blood cell analyzer 10 as an example, before the sample container carried in the sample rack 15 shown in fig. 6 enters the blood cell analyzer for sampling analysis, the blood cell analyzer 10 needs to scan the label of the sample container on the sample rack 15 to obtain the identity information of the corresponding sample and at least one to-be-detected mode, so that the side wall of each detection position on the sample rack 15 is provided with a scanning hole 153, which is convenient for the scanner to scan the label pasted on the sample container.
In an alternative embodiment, as shown in fig. 3, the feeding mechanism 61 further includes: an unloading buffer area 424 and an unloading mechanism 425, wherein the unloading buffer area 424 is positioned between the output end of the detection channel and the transmission channel, and the detection channel is communicated with the transmission channel, so that the sample container or the sample rack at the output end of the detection channel can enter the unloading buffer area 424.
The unloading buffer areas 424 and the loading buffer areas 422 are arranged at intervals along the transmission direction of the detection channel, as shown in fig. 3, and the loading buffer areas 422 and the unloading buffer areas 424 are respectively located at two ends of the detection channel.
An unloading mechanism 425 is located at the unloading buffer area 424 for transferring the sample containers or sample racks of the unloading buffer area 424 into the transport channel. In one embodiment, the unloading mechanism 425 may also be used to move sample containers or sample racks removed through the output end of the detection channel to the unloading buffer 424.
In the embodiment of the present application, for a detailed working principle and structure of the unloading mechanism, reference may be made to the foregoing description of the loading mechanism, and details are not described herein.
Example 5
In one embodiment of the present application, the blood sedimentation analyzer 20 includes a detection line for providing a detection site for a sample, and an optical detection portion (not shown in the figure) for irradiating light to the sample in the detection line and detecting the degree of absorption or scattering of the light by the sample to detect the erythrocyte sedimentation rate of the sample.
In one embodiment of the present application, the blood sedimentation analyzer 20 further comprises a power device (not shown) connected to the detection line, and the power device is used for driving the sample in the detection line to flow and stop and keep the sample after flowing to the detection area of the detection line, so that the optical detection portion detects the erythrocyte sedimentation rate of the sample in the detection area of the detection line. That is, the power device is not only used to drive the sample into the detection line, but also to ensure that the sample in the detection line remains stationary while the erythrocyte sedimentation rate is being detected.
Specifically, the working process of the blood sedimentation analyzer 20 provided by the embodiment of the present application to detect ESR is as follows: the sample is driven to flow into the detection line by the power device, and when the sample flows to a specific position (detection area) of the detection line, the power device interrupts the flow of the sample in the detection line instantaneously, so that the sample is decelerated (or stops flowing) suddenly at the moment, and then the aggregation and sedimentation of red blood cells occur. During the process of aggregation and sedimentation of the erythrocytes, this will cause a change in the signal detected by the optical detection portion, thus obtaining information for determining the ESR. In a specific embodiment, whether the sample flows to the detection area in the detection pipeline or not can be detected by a sample detection sensor arranged behind the detection area in the detection pipeline in the sample flowing direction, when the sample detection sensor monitors that the sample flows, the sample flows to the detection area, and the detection area is filled with the sample.
In one embodiment of the present application, the detection line is a capillary tube.
Example 6
Fig. 7 is a schematic diagram of another sample analysis system provided in an embodiment of the present application.
Referring to fig. 7, the sample analysis system includes a sedimentation analyzer 20, a blood cell analyzer 10, a slide dyeing machine 90, and a saccharification machine 100. In the transport direction X along the transport path, the slide dyeing machine 90 and the saccharification instrument 100 each correspond to one of the sample detection positions.
In the present embodiment, the layout of the blood cell analyzer 10, the blood sedimentation analyzer 20, the slide dyeing machine 90, and the saccharification instrument 100 can be freely arranged as needed. As shown in fig. 7, push slide dyeing machine 90 is located behind blood sedimentation analyzer 20, and saccharification equipment 100 is located behind push slide dyeing machine 90. In one embodiment, the hematology analyzer 10, the sedimentation analyzer 20, the push piece stainer 90, and the saccharification meter 100 are arranged in sequence from one to the next.
In addition, as shown in fig. 7, the sample analysis system may further include: a loading platform 70 and a platform loading mechanism 71, wherein the loading platform 70 is located at one end of the transmission channel, and the loading platform 70 is used for placing a sample container to be tested or a sample rack containing the sample container to be tested. In the embodiment of the present application, the loading platform 70 is located at the front end of the transport direction X of the transport channel, that is, the sample rack is moved from the loading platform 70 to the transport channel, and then is transported to each analyzer through the transport channel. The stage loading mechanism 71 is used to transfer the sample rack on the loading stage 70 to the transfer passage.
In addition, in this embodiment of the present application, the sample analysis system further includes: a sample rack detector (not shown), wherein the sample rack detector is disposed on the loading platform 70 and is used for detecting the sample container on the loading platform 70, and the sample rack detector sends a transfer signal after detecting the sample container on the loading platform 70. The stage loading mechanism 71 is electrically connected to the sample rack detector, and when the stage loading mechanism 71 receives the transfer signal, the stage loading mechanism 71 transfers the sample container from the loading stage 70 to the transport path.
As shown in fig. 7, in the embodiment of the present application, the sample analysis system further includes: an unloading platform 80 and a platform unloading mechanism 81, wherein the unloading platform 80 is arranged at the other end of the transmission channel, and the unloading platform 80 is used for placing the tested sample container or the sample rack loaded with the tested sample container. Referring to fig. 7, the unloading platform 80 is disposed at the end of the transfer direction X of the transfer passage. When the samples in the sample containers on the sample racks on the transport path are all detected, the sample racks are all transported to the unloading platform 80 for storage. The platform unloading mechanism 81 is used to transfer the sample container in the transfer passage to the unloading platform 80.
The above description is only exemplary of the invention, and is intended to enable those skilled in the art to understand and implement the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (11)
1. A sample analysis system, comprising: a blood sedimentation analyzer, a blood cell analyzer, a transport mechanism, a sample identification device, and a dispatch control device, wherein,
the conveying mechanism is internally provided with a conveying channel for conveying sample containers loaded with samples, and at least two sample detection positions are arranged in the conveying direction of the conveying channel;
the blood sedimentation analyzer and the blood cell analyzer respectively correspond to one sample detection position;
the erythrocyte sedimentation rate detection device is used for detecting the erythrocyte sedimentation rate of the sample in the sample container conveyed to the corresponding sample detection position by the conveying mechanism, the sample flows in the detection pipeline, the sample stops moving when flowing to the detection area in the detection pipeline, the sample in the detection area is irradiated by light, and the absorption or scattering degree of the sample in the detection area to the light is detected;
the blood cell analyzer is used for carrying out routine blood detection on the sample in the sample container conveyed to the sample detection position corresponding to the blood cell analyzer by the conveying mechanism;
the sample identification device is used for scanning the sample container conveyed on the conveying channel to obtain the identity information of the sample in the sample container and at least one to-be-detected mode corresponding to the identity information;
the dispatching control device is respectively electrically connected with the sample identification device and the transmission mechanism, and is used for receiving the identity information sent by the sample identification device and at least one to-be-detected mode corresponding to the identity information, and controlling the transmission mechanism to convey the sample container to a sample detection position corresponding to the at least one to-be-detected mode, so that the corresponding detection of the sample in the sample container is performed by the erythrocyte analyzer or the erythrocyte analyzer corresponding to the sample detection position.
2. The sample analysis system of claim 1, wherein the blood cell analyzer is positioned in front of the blood sedimentation analyzer in a transport direction along the transport channel.
3. The sample analysis system of claim 1, wherein the dispatch control device is configured to control the transport mechanism to transport the sample container to a sample testing location corresponding to the hematology analyzer prior to transporting the sample container to a sample testing location corresponding to the hematology analyzer when the at least one mode of the sample container to be tested includes a red blood cell sedimentation rate testing mode and a blood routine testing mode.
4. The sample analysis system according to any one of claims 1 to 3, wherein the at least two sample detection sites are disposed within the transport channel and sample containers transported within the transport channel pass the at least two sample detection sites in sequence along the transport direction of the transport channel.
5. The sample analysis system according to any one of claims 1 to 3,
the conveying mechanism further comprises at least two feeding mechanisms, wherein the at least two feeding mechanisms are connected with the conveying channel, each sample detection position corresponds to one feeding mechanism, a detection channel is arranged in each feeding mechanism, and each sample detection position is located in the corresponding detection channel of the feeding mechanism;
the feeding mechanism is used for transferring the sample containers in the transmission channels to the corresponding detection channels and transferring the sample containers in the corresponding detection channels to the transmission channels.
6. The sample analysis system of claim 5, wherein each feed mechanism further comprises:
a transmission mechanism formed with a detection channel;
the loading buffer area is positioned between the input end of the detection channel and the transmission channel and communicates the detection channel with the transmission channel, so that a sample container on the transmission channel can enter the loading buffer area;
and the loading mechanism is positioned in the loading buffer area and used for transferring the sample container in the loading buffer area to the input end of the detection channel.
7. The sample analysis system of claim 6, wherein the feed mechanism further comprises:
the unloading buffer area is positioned between the output end of the detection channel and the transmission channel and communicates the detection channel with the transmission channel, so that a sample container in the output end of the detection channel can enter the unloading buffer area;
and the unloading mechanism is positioned in the unloading buffer area and used for transferring the sample container in the unloading buffer area to the conveying channel.
8. The sample analysis system according to any one of claims 1 to 3, wherein the sedimentation analyzer comprises a power device connected to the detection line, the power device being configured to drive the sample to flow into the detection line, and to stop and keep the sample stationary after flowing to the detection area of the detection line, so as to irradiate the sample in the detection area with light.
9. The sample analysis system of any of claims 1-3, further comprising: and the display is used for receiving the detection result sent by the blood sedimentation analyzer and/or the blood corpuscle analyzer and displaying the detection result in a display interface.
10. The sample analysis system of any of claims 1-3, further comprising: and the data storage device is used for receiving and storing the detection result sent by the blood sedimentation analyzer and/or the blood corpuscle analyzer.
11. The sample analysis system of any of claims 1-3, further comprising a plug-dyeing machine and/or a saccharification machine, each corresponding to one of the sample stations.
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| CN201921994354.7U CN212059805U (en) | 2019-11-18 | 2019-11-18 | Sample analysis system |
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| CN201921994354.7U CN212059805U (en) | 2019-11-18 | 2019-11-18 | Sample analysis system |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114264831A (en) * | 2021-12-17 | 2022-04-01 | 深圳市爱康生物科技股份有限公司 | Test tube carrier scheduling method |
| WO2022143457A1 (en) * | 2020-12-29 | 2022-07-07 | 安图实验仪器(郑州)有限公司 | Automatic loading system for extraction strip |
| CN114755436A (en) * | 2022-06-13 | 2022-07-15 | 深圳市帝迈生物技术有限公司 | Sample detection control method, system and control equipment |
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2019
- 2019-11-18 CN CN201921994354.7U patent/CN212059805U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022143457A1 (en) * | 2020-12-29 | 2022-07-07 | 安图实验仪器(郑州)有限公司 | Automatic loading system for extraction strip |
| CN114264831A (en) * | 2021-12-17 | 2022-04-01 | 深圳市爱康生物科技股份有限公司 | Test tube carrier scheduling method |
| CN114264831B (en) * | 2021-12-17 | 2022-08-05 | 深圳市爱康生物科技股份有限公司 | Test tube carrier scheduling method |
| CN114755436A (en) * | 2022-06-13 | 2022-07-15 | 深圳市帝迈生物技术有限公司 | Sample detection control method, system and control equipment |
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