CN212007975U - Sampling device of medicinal automatic dissolution instrument - Google Patents
Sampling device of medicinal automatic dissolution instrument Download PDFInfo
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- CN212007975U CN212007975U CN202020837658.9U CN202020837658U CN212007975U CN 212007975 U CN212007975 U CN 212007975U CN 202020837658 U CN202020837658 U CN 202020837658U CN 212007975 U CN212007975 U CN 212007975U
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Abstract
The utility model provides a sampling device of a medicinal automatic dissolution instrument, in particular to the technical field of dissolution equipment. The utility model comprises a dissolving-out cup and a sampling cup, wherein the lower ends of the dissolving-out cup and the sampling cup are provided with mounting plates, the mounting plates are provided with fixing plates, the fixing plates are provided with rotating plates and motors, the rotating plates are rotatably connected with the fixing plates, and the rotating shafts of the motors are in rolling connection with the rotating plates; the rotating plate is provided with a fixed rod, the fixed rod is provided with a fixed block, the fixed rod penetrates through the fixed block, and the fixed block is rotatably connected with the fixed rod; the fixing block is provided with at least one mounting rod, the mounting rod is provided with a liquid taking barrel, a cylinder is arranged between the liquid taking barrel and the fixing block, the cylinder penetrates through the upper end face of the liquid taking barrel, a mandril of the cylinder is provided with a piston, and the piston is connected with the inner wall of the liquid taking barrel in a sliding manner; the liquid taking cylinder is provided with a sampling tube. The utility model provides a sampling device of appearance is dissolved out automatically to medicinal, extraction that can be quick accurate has experimental sample, improves experimental efficiency.
Description
Technical Field
The utility model belongs to the technical field of dissolving out equipment, concretely relates to sampling device of automatic appearance of dissolving out of medicine.
Background
Drug dissolution is the rate and extent of dissolution of a drug from a solid formulation such as a tablet in a given solvent. Dissolution rate is an important index for controlling the quality of tablets, and the dissolution rate of insoluble medicines is generally checked. The medicinal dissolution instrument is important equipment for detecting the dissolution rate of a medicament, and in the detection process, the sampling needs to be carried out quickly and accurately, and the existing sampling methods comprise two methods: one is to use an automatic sampler for sampling, but the automatic sampler has a complex structure and is expensive; the other method is to manually sample by a sampling needle, but the manual sampling can cause large experimental error, so that the experimental result is not accurate enough. Therefore, there is a need for a sampling device for a medical automatic dissolution apparatus that can solve the above problems.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a sampling device of appearance is dissolved out in medicinal automation can be fast accurate extract experimental sample, improves experimental efficiency.
The utility model provides a following technical scheme:
a sampling device of a medicinal automatic dissolution instrument comprises a dissolution cup and a sampling cup, wherein mounting plates are arranged at the lower ends of the dissolution cup and the sampling cup, a fixing plate is arranged on the mounting plates, a rotating plate and a motor are arranged on the fixing plate, the rotating plate is rotatably connected with the fixing plate, and a rotating shaft of the motor is in rolling connection with the rotating plate; the rotating plate is provided with a fixed rod, the fixed rod is provided with a fixed block, the fixed rod penetrates through the fixed block, and the fixed block is rotatably connected with the fixed rod; the liquid taking device comprises a fixing block, a liquid taking cylinder, a piston and a liquid taking device, wherein the fixing block is provided with at least one mounting rod, the mounting rod is provided with the liquid taking cylinder, the cylinder is arranged between the liquid taking cylinder and the fixing block, the cylinder penetrates through the upper end surface of the liquid taking cylinder, a top rod of the cylinder is provided with the piston, and the piston is connected with the inner wall of the liquid taking cylinder in a sliding manner; the sampling tube is arranged on the liquid taking barrel, and the lower end of the sampling tube is respectively arranged below the liquid level of the sample in the sampling cup and the dissolution cup.
Preferably, first auxiliary pipes are respectively arranged in the dissolution cup and the sampling cup, and connecting rods are respectively arranged between the first auxiliary pipes and the dissolution cup and between the first auxiliary pipes and the sampling cup.
Preferably, a second auxiliary pipe is arranged at the upper end of the first auxiliary pipe, and the radius of the upper end of the second auxiliary pipe is larger than that of the lower end of the second auxiliary pipe.
Preferably, the upper end of the liquid taking cylinder is provided with a bulge, and the bulge is in sliding connection with an ejector rod of the air cylinder.
Preferably, the edge of the rotating plate is provided with gear teeth.
Preferably, a gear matched with the gear teeth is arranged on a rotating shaft of the motor, and the gear is meshed with the rotating plate.
Preferably, the upper end of the mounting plate is provided with a groove matched with the sampling cup and the dissolving-out cup, and the bottom of the groove is respectively connected with the sampling cup and the dissolving-out cup.
The utility model discloses a profitable effect:
the utility model discloses the lower extreme of dissolving out cup and sampling cup is equipped with the mounting panel, is equipped with the fixed plate on the mounting panel, is equipped with commentaries on classics board and motor on the fixed plate, and the commentaries on classics board rotates with the fixed plate to be connected, and the pivot and the commentaries on classics board roll connection of motor, and the mounting panel is convenient for fix dissolving out cup and sampling cup, and the commentaries on classics board rotates through the;
the rotating plate is provided with a fixed rod, the fixed rod is provided with a fixed block, the fixed rod penetrates through the fixed block, the fixed block is rotationally connected with the fixed rod, the fixed block is provided with at least one mounting rod, the mounting rod is provided with a liquid taking barrel, a cylinder is arranged between the liquid taking barrel and the fixed block and penetrates through the upper end face of the liquid taking barrel, the ejector rod of the cylinder is provided with a piston, the piston is in sliding connection with the inner wall of the liquid taking barrel, the liquid taking barrel is provided with a sampling tube, the lower end of the sampling tube is respectively arranged below the liquid level of the sample in the, the cylinder and the liquid taking cylinder are always positioned at the lower end of the fixed block due to gravity, the sampling tube realizes back-and-forth conversion between the dissolving-out cup and the sampling cup through rotation of the rotating plate, the liquid taking cylinder drives the piston to move through the cylinder, air pressure in the liquid taking cylinder is changed, extraction and discharge of samples are realized, quantitative samples can be taken out quickly and accurately in the whole process, and the operation is simple and convenient.
Drawings
The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention. In the drawings:
fig. 1 is a schematic structural diagram of the present invention;
fig. 2 is a partial enlarged view of the present invention.
Description of reference numerals:
1. a dissolution cup; 2. a sampling cup; 3. mounting a plate; 4. a groove; 5. a fixing plate; 6. rotating the plate; 7. a motor; 8. gear teeth; 9. a gear; 10. fixing the rod; 11. a fixed block; 12. mounting a rod; 13. a cylinder; 14. a protrusion; 15. a piston; 16. a liquid taking cylinder; 17. a sampling tube; 18. a first auxiliary tube; 19. a connecting rod; 20. a second auxiliary tube.
Detailed Description
As shown in fig. 1 and 2, a sampling device of a medical automatic dissolution instrument comprises a dissolution cup 1 and a sampling cup 2, wherein the lower ends of the dissolution cup 1 and the sampling cup 2 are provided with a mounting plate 3 along the horizontal direction, the upper end of the mounting plate 3 is provided with a groove 4 matched with the sampling cup 2 and the dissolution cup 1, the bottom of the groove 4 is respectively connected with the sampling cup 2 and the dissolution cup 1, and the groove 4 ensures that the sampling cup 2 and the dissolution cup 1 are more firmly fixed; the upper end of the mounting plate 3 is provided with a fixing plate 5 along the vertical direction, and the lower end of the fixing plate 5 is connected with the mounting plate 3; the side end face of the fixed plate 5 is provided with a rotating plate 6 and a motor 7, the rotating plate 6 is rotatably connected with the fixed plate 5, the edge of the rotating plate 6 is provided with a gear tooth 8, a rotating shaft of the motor 7 is provided with a gear 9 matched with the gear tooth 8, the gear 9 is meshed with the rotating plate 6 and is connected with the rotating plate 7, and the motor 7 drives the rotating plate 6 to rotate.
A fixing rod 10 is arranged on the side end face of the rotating plate 6, a fixing block 11 is arranged on the fixing rod 10, the fixing rod 10 penetrates through the fixing block 11, and the fixing block 11 is rotatably connected with the side wall of the fixing rod 10; the lower extreme of fixed block 11 is equipped with four installation poles 12, the lateral wall of installation pole 12 is equipped with gets liquid section of thick bamboo 16, get the lateral wall of liquid section of thick bamboo 16 and meet with installation pole 12, it is equipped with cylinder 13 to get between liquid section of thick bamboo 16 and the fixed block 11, the cylinder body tip of cylinder 13 meets with fixed block 11, the ejector pin end of cylinder 13 runs through the up end of getting liquid section of thick bamboo 16, be equipped with piston 15 on the ejector pin of cylinder 13, piston 15 and the inner wall sliding connection who gets liquid section of thick bamboo 16, the upper end of getting liquid section of thick bamboo 16 is equipped with arch 14, arch 14 and the ejector pin lateral wall sliding connection of cylinder 13, arch 14 can prevent that piston 15 roll.
The lower end of a liquid taking cylinder 16 is provided with a sampling tube 17, the upper end of the sampling tube 17 is connected with the liquid taking cylinder 16, a first auxiliary tube 18 is respectively arranged in a dissolving cup 1 and a sampling cup 2, a connecting rod 19 is respectively arranged between the first auxiliary tube 18 and the dissolving cup 1 and the sampling cup 2, one end of the connecting rod 19 is connected with the outer side wall of the first auxiliary tube 18, the other end of the connecting rod 19 is connected with the inner side wall of the dissolving cup 1 and the inner side wall of the sampling cup 2, the connecting rod 19 is favorable for fixing the first auxiliary tube 18, the first auxiliary tube 18 is favorable for the sampling tube 17 to extract and discharge samples, the upper end of the first auxiliary tube 18 is provided with a second auxiliary tube 20, the radius of the lower end of the radius wall of the upper end of the second auxiliary tube 20 is one centimeter larger, and the second auxiliary tube 20 is favorable for connecting the sampling tube 17; the installation pole 12, the cylinder 13 and get a liquid section of thick bamboo 16 and be located the lower extreme of fixed block 11 all the time because of gravity reason, and the rotation of sampling tube 17 through the commentaries on classics board has realized dissolving out the conversion back and forth between cup 1 and the sampling cup 2, gets a liquid section of thick bamboo 16 and drives piston 15 through cylinder 13 and move, changes the atmospheric pressure of getting in the liquid section of thick bamboo 16, realizes the extraction and the discharge of sample, and whole process can be fast accurate take out quantitative sample, and easy operation is convenient.
The utility model discloses a working method: when the rotating plate 6 is rotated, the piston 15 slides to the bottom end of the liquid taking cylinder 16 through the air cylinder 13 to discharge air in the liquid taking cylinder 16, then the lower end of the sampling tube 17 is connected with the lower end of the first auxiliary tube 18, the piston 15 slides upwards through the air cylinder 13 to extract a sample in the dissolution cup 1, after extraction, the rotating plate 6 is rotated, the lower end of the sampling tube 17 is moved to the upper end of the first auxiliary tube 18 in the sampling cup 2, and the piston 15 moves downwards through the air cylinder 13 to discharge the sample in the liquid taking cylinder 16 into the sampling cup 2.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing embodiments, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (7)
1. The utility model provides a sampling device of medicinal automatic appearance of dissolving out, includes dissolving out cup and sample cup, its characterized in that: the lower ends of the dissolution cup and the sampling cup are provided with mounting plates, the mounting plates are provided with fixing plates, the fixing plates are provided with rotating plates and motors, the rotating plates are rotatably connected with the fixing plates, and rotating shafts of the motors are in rolling connection with the rotating plates; the rotating plate is provided with a fixed rod, the fixed rod is provided with a fixed block, the fixed rod penetrates through the fixed block, and the fixed block is rotatably connected with the fixed rod; the liquid taking device comprises a fixing block, a liquid taking cylinder, a piston and a liquid taking device, wherein the fixing block is provided with at least one mounting rod, the mounting rod is provided with the liquid taking cylinder, the cylinder is arranged between the liquid taking cylinder and the fixing block, the cylinder penetrates through the upper end surface of the liquid taking cylinder, a top rod of the cylinder is provided with the piston, and the piston is connected with the inner wall of the liquid taking cylinder in a sliding manner; the sampling tube is arranged on the liquid taking barrel, and the lower end of the sampling tube is respectively arranged below the liquid level of the sample in the sampling cup and the dissolution cup.
2. The sampling device of a pharmaceutical automatic dissolution apparatus according to claim 1, characterized in that: first auxiliary pipes are respectively arranged in the dissolving-out cup and the sampling cup, and connecting rods are respectively arranged between the first auxiliary pipes and the dissolving-out cup and between the first auxiliary pipes and the sampling cup.
3. A sampling device for a medical automatic dissolution apparatus according to claim 2, characterized in that: the upper end of the first auxiliary pipe is provided with a second auxiliary pipe, and the radius of the upper end of the second auxiliary pipe is larger than that of the lower end of the second auxiliary pipe.
4. The sampling device of a pharmaceutical automatic dissolution apparatus according to claim 1, characterized in that: the upper end of the liquid taking barrel is provided with a bulge, and the bulge is connected with the ejector rod of the air cylinder in a sliding manner.
5. The sampling device of a pharmaceutical automatic dissolution apparatus according to claim 1, characterized in that: the edge of the rotating plate is provided with gear teeth.
6. The sampling device of an automatic dissolution apparatus for pharmaceutical use according to claim 5, wherein: and a gear matched with the gear teeth is arranged on a rotating shaft of the motor, and the gear is meshed with the rotating plate.
7. The sampling device of a pharmaceutical automatic dissolution apparatus according to claim 1, characterized in that: the upper end of the mounting plate is provided with a groove matched with the sampling cup and the dissolving-out cup, and the bottom of the groove is respectively connected with the sampling cup and the dissolving-out cup.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202020837658.9U CN212007975U (en) | 2020-05-19 | 2020-05-19 | Sampling device of medicinal automatic dissolution instrument |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202020837658.9U CN212007975U (en) | 2020-05-19 | 2020-05-19 | Sampling device of medicinal automatic dissolution instrument |
Publications (1)
Publication Number | Publication Date |
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CN212007975U true CN212007975U (en) | 2020-11-24 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN202020837658.9U Active CN212007975U (en) | 2020-05-19 | 2020-05-19 | Sampling device of medicinal automatic dissolution instrument |
Country Status (1)
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CN (1) | CN212007975U (en) |
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2020
- 2020-05-19 CN CN202020837658.9U patent/CN212007975U/en active Active
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