CN110887702B - Sterile sampling device - Google Patents
Sterile sampling device Download PDFInfo
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- CN110887702B CN110887702B CN201911110019.0A CN201911110019A CN110887702B CN 110887702 B CN110887702 B CN 110887702B CN 201911110019 A CN201911110019 A CN 201911110019A CN 110887702 B CN110887702 B CN 110887702B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
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- Sampling And Sample Adjustment (AREA)
Abstract
The invention belongs to the field of pharmaceutical auxiliary equipment, in particular to an aseptic sampling device, which aims at the problems that the conventional liquid medicine sampling device generally finishes sampling in a manual operation mode, the manual labor amount is large, and the practicability is poor; and the leakproofness of current liquid medicine sampling device's sample collection container is relatively poor, can't guarantee aseptic sample, the relatively poor problem of operating mass, the scheme is put forward now, it includes the base case, install the supporting box directly over the base case and install the lift seat directly over the supporting box, be connected with the support column through the bearing rotation on the interior roof of base case, the outer lane of the support column that is located the base incasement portion is fixed to be cup jointed the awl ring gear, the interior wall-mounting of base case has first step motor, the output fixedly connected with bevel gear of first step motor. The invention has novel design, convenient use, higher automation degree, less manual labor amount, good sealing performance of the container, capability of automatically completing sampling, capability of ensuring aseptic sampling and higher working quality.
Description
Technical Field
The invention relates to the technical field of pharmaceutical auxiliary equipment, in particular to an aseptic sampling device.
Background
Pharmaceutical engineering is a science and technology that intersects chemistry, biology, pharmacy and engineering, and aims to develop, amplify and design talents involved in drug research and development, new processes, new equipment and new varieties. Although the pharmaceutical engineering profession is new in name, its generation is not completely new from the discipline and is a continuation of the near profession and a product of the development of science and technology. After the liquid medicine is manufactured, in order to ensure the product quality of the liquid medicine, the liquid medicine needs to be sampled by a liquid medicine sampling device and then detected.
However, the existing liquid medicine sampling device generally completes sampling in a manual operation mode, so that the manual labor amount is large, and the practicability is poor; in addition, the sample collection container of the conventional liquid medicine sampling device is poor in sealing performance, aseptic sampling cannot be guaranteed, and the working quality is poor, so that the aseptic sampling device is provided.
Disclosure of Invention
The sterile sampling device provided by the invention solves the problems that the conventional liquid medicine sampling device generally finishes sampling in a manual operation mode, the manual labor amount is large, and the practicability is poor; and the sample collecting container of the existing liquid medicine sampling device has poor tightness, can not ensure aseptic sampling and has poor working quality.
In order to achieve the purpose, the invention adopts the following technical scheme:
an aseptic sampling device comprises a base box, a supporting box arranged right above the base box and a lifting seat arranged right above the supporting box, wherein a vertical supporting column is rotatably connected to the inner top wall of the base box through a bearing, a bevel gear ring is fixedly sleeved on the outer ring of the supporting column positioned inside the base box, a first stepping motor is arranged on the inner bottom wall of the base box, a bevel gear is fixedly connected to the output end of the first stepping motor, the bevel gear is meshed with the bevel gear ring and is connected with the outer bottom wall of the supporting box, the top end of the supporting column is fixedly connected to the outer bottom wall of the supporting box, two sides of the top wall of the supporting box are respectively rotatably connected with a vertical lead screw through a bearing, a gear ring is fixedly sleeved on the outer ring of the lead screw positioned inside the supporting box, a second stepping motor is arranged in the middle position of the inner bottom wall of the supporting box, and a gear is fixedly connected to the output, two the ring gear all with gear engagement connects, two the outer lane spiral cooperation of lead screw is connected with the lift seat, the equal fixed connection in both ends of lift seat has the horizontally mounting panel, the interior bottom wall mounting of mounting panel has the collecting box, install miniature self priming pump on the diapire of mounting panel, the top of miniature self priming pump is provided with the fluid-discharge tube, and the top of fluid-discharge tube is connected with the transfer line, the through-hole has been seted up on the roof of collecting box, the one end that miniature self priming pump was kept away from to the transfer line runs through the inside that the through-hole just extended to the collecting box.
Preferably, the outer top wall of the support box between the two screw rods is fixedly connected with a vertical limiting rod, and the lifting seat is in clearance fit with the outer ring of the limiting rod.
Preferably, the top of gag lever post extends to the top of lift seat and welds and have the limiting plate, the top of lead screw with the top of gag lever post flushes.
Preferably, the bottom of support column passes through the bearing and rotates the connection on the interior diapire of base case, the bottom of lead screw passes through the bearing and rotates the connection on the interior diapire of support case.
Preferably, universal wheels are mounted at four corners of the outer bottom wall of the base box.
Preferably, a sealing sleeve made of a rubber material is in interference fit in the through hole, and the infusion tube is fixedly sleeved on an inner ring of the sealing sleeve.
Preferably, the top wall of the mounting plate is welded with a vertical limiting pipe, the collecting box is movably sleeved on an inner ring of the limiting pipe, and a handle is fixed on the outer side wall of the collecting box above the limiting pipe.
Preferably, the bottom end of the miniature self-priming pump is provided with a pipette, and the bottom end of the pipette is fixedly connected with a sampling tube.
The invention has the beneficial effects that:
1. through the foundation box, first step motor, the second step motor, the universal wheel, the support column, the supporting box, the lead screw, the seat that goes up and down, the mounting panel, miniature self priming pump, the transfer line, the mating reaction of sampling tube and collecting box, through passing aseptic sampling device, make aseptic sampling device remove to near of the liquid medicine that needs the sample, through the mating reaction of first step motor, second step motor and miniature self priming pump, can accomplish the sample automatically, degree of automation is higher, the amount of labour is less, and the practicality is higher.
2. Through the cooperation of collecting box, through-hole, transfer line and seal cover, through the interference fit of seal cover and through-hole, can guarantee the leakproofness of collecting the container, can guarantee aseptic sample, work quality is higher.
Drawings
Fig. 1 is a schematic structural diagram of an aseptic sampling device according to the present invention.
Fig. 2 is a partially enlarged view of a portion a in fig. 1.
Fig. 3 is a partially enlarged view of a portion B in fig. 1.
Fig. 4 is a partially enlarged view of a portion C in fig. 1.
Fig. 5 is a partially enlarged view of a portion D in fig. 1.
Fig. 6 is a top view of the top of the lifting seat of the sterile sampling device of the present invention.
Reference numbers in the figures: 1. a base case; 2. a first stepper motor; 3. a universal wheel; 4. a support pillar; 5. a support box; 6. a screw rod; 7. a limiting rod; 8. a lifting seat; 9. mounting a plate; 10. a limiting pipe; 11. a transfusion tube; 12. a collection box; 13. a micro self-priming pump; 14. a sampling tube; 15. a bevel gear; 16. a bevel gear ring; 17. a second stepping motor; 18. a gear; 19. a ring gear; 20. a through hole; 21. and (5) sealing the sleeve.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Referring to fig. 1-6, the sterile sampling device comprises a base box 1, a supporting box 5 arranged right above the base box 1 and a lifting seat 8 arranged right above the supporting box 5, wherein the inner top wall of the base box 1 is rotatably connected with a vertical supporting column 4 through a bearing, a bevel gear ring 16 is fixedly sleeved on the outer ring of the supporting column 4 positioned inside the base box 1, a first stepping motor 2 is arranged on the inner bottom wall of the base box 1, the output end of the first stepping motor 2 is fixedly connected with a bevel gear 15, the bevel gear 15 is meshed with the bevel gear ring 16, the top end of the supporting column 4 is fixedly connected with the outer bottom wall of the supporting box 5, two sides of the top wall of the supporting box 5 are rotatably connected with vertical screw rods 6 through bearings, the outer ring of the screw rod 6 positioned inside the supporting box 5 is fixedly sleeved with a gear ring 19, and a second stepping motor 17 is arranged in the middle position of the inner bottom wall of the supporting, the output end of the second stepping motor 17 is fixedly connected with a gear 18, two gear rings 19 are all meshed with the gear 18, the outer rings of the two lead screws 6 are spirally connected with a lifting seat 8, two ends of the lifting seat 8 are fixedly connected with horizontal mounting plates 9, a collecting box 12 is mounted on the inner bottom wall of each mounting plate 9, a miniature self-sucking pump 13 is mounted on the bottom wall of each mounting plate 9, a pipette is arranged at the bottom end of each miniature self-sucking pump 13, a sampling tube 14 is fixedly connected to the bottom end of the pipette, a liquid discharge tube is arranged at the top end of each miniature self-sucking pump 13, a liquid conveying tube 11 is connected to the top end of each pipette, a through hole 20 is formed in the top wall of each collecting box 12, one end, far away from each miniature self-sucking pump 13, of each liquid conveying tube 11 penetrates through the through hole 20 and extends into the corresponding collecting box 12, a first controller with, a second controller with the model number of PIC18F2520 is installed at the side end of the second stepping motor 17, and the bidirectional operation of the second stepping motor 17 can be controlled through the second controller.
The outer top wall of the supporting box 5 between the two screw rods 6 is fixedly connected with a vertical limiting rod 7, and the lifting seat 8 is in clearance fit with the outer ring of the limiting rod 7, so that the lifting seat 8 can be stably lifted.
The top of gag lever post 7 extends to the top of lift seat 8 and welds and has the limiting plate, and the top of lead screw 6 flushes with the top of gag lever post 7, can prevent that lift seat 8 from breaking away from lead screw 6 and gag lever post 7.
The bottom of support column 4 is passed through the bearing and is rotated the connection on the interior diapire of base case 1, can guarantee the stability of support column 4, and the bottom of lead screw 6 is passed through the bearing and is rotated the connection on the interior diapire of support case 5, can guarantee the stability of lead screw 6.
A sealing sleeve 21 made of rubber material is in interference fit in the through hole 20, and the infusion tube 11 is fixedly sleeved on an inner ring of the sealing sleeve 21.
The welding has the spacing pipe 10 of vertically on the roof of mounting panel 9, and the inner circle at spacing pipe 10 is cup jointed in the activity of collecting box 12, is located the lateral wall of the collecting box 12 of spacing pipe 10 top and is fixed with the handle, when the sample is accomplished the back, can conveniently mention collecting box 12.
Example (b): when the liquid medicine needs to be sampled, the whole sterile sampling device is moved to the position near the liquid medicine by pushing the base box 1, then the sampling tube 14 can be driven to rotate by the operation of the first stepping motor 2 and the transmission of the bevel gear 15 and the bevel gear ring 16 to drive the supporting column 4, the supporting box 5, the screw rod 6 and the lifting seat 8 to rotate until the sampling tube 14 rotates right above the liquid level of the liquid medicine, then the sampling tube 14 can be driven to descend by the forward operation of the second stepping motor 17 and the transmission of the gear 18 and the gear ring 19 to drive the screw rod 6 to rotate, the lifting seat 8 can descend by the spiral transmission of the screw rod 6 and the lifting seat 8 to drive the sampling tube 14 to descend until the bottom end of the sampling tube 14 descends to be below the liquid level of the liquid medicine, and then the liquid medicine can be transmitted to the collecting box 12 by the operation of the micro self-priming pump 13, because the infusion tube 21 is made of rubber material, the fixed inner circle that cup joints at seal cover 21 of transfer line 11, and seal cover 21 and the 20 interference fit of through-hole on the collecting box 12, can guarantee collecting box 12 leakproofness, thereby the leakproofness of aseptic sampling device's collection container has been guaranteed, aseptic sampling device's aseptic sample has been guaranteed, transmit the liquid medicine to the inside back of collecting box 12, reverse operation through second step motor 17, transmission through gear 18 and ring gear 19, but electronic lead screw 6 rotates, through the screw drive of lead screw 6 and lift seat 8, can make lift seat 8 rise, can drive sampling tube 14 and rise, rise to the liquid level of liquid medicine up to the bottom of sampling tube 14, can realize automatic completion sample.
The invention has novel design, convenient use, higher automation degree, automatic sampling, smaller amount of manual labor, higher practicability, good sealing property of the container, capability of ensuring aseptic sampling and higher working quality.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the equipment or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (5)
1. An aseptic sampling device comprises a base box (1), a supporting box (5) arranged right above the base box (1) and a lifting seat (8) arranged right above the supporting box (5), and is characterized in that the inner top wall of the base box (1) is rotatably connected with a vertical supporting column (4) through a bearing, the outer ring of the supporting column (4) positioned inside the base box (1) is fixedly sleeved with a bevel gear ring (16), the inner bottom wall of the base box (1) is provided with a first stepping motor (2), the output end of the first stepping motor (2) is fixedly connected with a bevel gear (15), the bevel gear (15) is meshed with the bevel gear ring (16), the top end of the supporting column (4) is fixedly connected on the outer bottom wall of the supporting box (5), two sides of the top wall of the supporting box (5) are rotatably connected with vertical screw rods (6) through bearings, the outer ring of the screw rod (6) positioned inside the support box (5) is fixedly sleeved with a gear ring (19), a second stepping motor (17) is installed at the middle position of the inner bottom wall of the support box (5), a gear (18) is fixedly connected with the output end of the second stepping motor (17), the gear rings (19) are respectively meshed with the gear (18) for connection, two lifting seats (8) are spirally and cooperatively connected with the outer ring of the screw rod (6), horizontal mounting plates (9) are respectively and fixedly connected with the two ends of the lifting seats (8), a collecting box (12) is installed on the inner bottom wall of the mounting plate (9), a micro self-priming pump (13) is installed on the bottom wall of the mounting plate (9), a liquid discharge pipe is arranged at the top end of the micro self-priming pump (13), the top end of the liquid discharge pipe is connected with a liquid transfer pipe (11), a through hole (20) is formed in, one end of the infusion tube (11) far away from the micro self-priming pump (13) penetrates through the through hole (20) and extends into the collecting box (12);
a sealing sleeve (21) made of rubber materials is arranged in the through hole (20) in an interference fit mode, and the infusion tube (11) is fixedly sleeved on an inner ring of the sealing sleeve (21);
a vertical limiting pipe (10) is welded on the top wall of the mounting plate (9), the collecting box (12) is movably sleeved on the inner ring of the limiting pipe (10), and a handle is fixed on the outer side wall of the collecting box (12) above the limiting pipe (10);
the bottom end of the miniature self-sucking pump (13) is provided with a liquid sucking pipe, and the bottom end of the liquid sucking pipe is fixedly connected with a sampling pipe (14).
2. An aseptic sampling device according to claim 1, characterized in that a vertical limit rod (7) is fixedly connected to the outer top wall of the support box (5) between the two screw rods (6), and the lifting seat (8) is in clearance fit with the outer ring of the limit rod (7).
3. The aseptic sampling device according to claim 2, characterized in that the top end of the limit rod (7) extends to the upper part of the lifting seat (8) and is welded with a limit plate, and the top end of the screw rod (6) is flush with the top end of the limit rod (7).
4. The aseptic sampling device according to claim 1, characterized in that the bottom end of the support column (4) is rotatably connected to the inner bottom wall of the base box (1) through a bearing, and the bottom end of the screw rod (6) is rotatably connected to the inner bottom wall of the support box (5) through a bearing.
5. An aseptic sampling device according to claim 1, characterized in that the four corners of the outer bottom wall of the base box (1) are fitted with universal wheels (3).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911110019.0A CN110887702B (en) | 2019-11-14 | 2019-11-14 | Sterile sampling device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911110019.0A CN110887702B (en) | 2019-11-14 | 2019-11-14 | Sterile sampling device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110887702A CN110887702A (en) | 2020-03-17 |
| CN110887702B true CN110887702B (en) | 2020-12-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911110019.0A Active CN110887702B (en) | 2019-11-14 | 2019-11-14 | Sterile sampling device |
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| CN (1) | CN110887702B (en) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN203820787U (en) * | 2014-05-16 | 2014-09-10 | 上海森松制药设备工程有限公司 | Aseptic sampling receiving flask |
| US9677975B2 (en) * | 2014-10-31 | 2017-06-13 | General Electric Company | Systems and methods for aseptic sampling |
| CN108801724B (en) * | 2018-03-26 | 2021-09-24 | 翟如扬 | Sample treatment device for sewage pollutant inspection |
| CN208265753U (en) * | 2018-05-06 | 2018-12-21 | 漳州塔斯克自动化科技有限公司 | A kind of automatic filling device |
| CN209027855U (en) * | 2018-08-29 | 2019-06-25 | 高全明 | A kind of food safety detection sample devices |
| CN209459955U (en) * | 2018-09-21 | 2019-10-01 | 大连神华轻工机械有限公司 | A kind of bio-pharmaceuticals sampler |
| CN208959787U (en) * | 2018-09-28 | 2019-06-11 | 王文慧 | A kind of miscible device for pharmacy test |
| CN109044829B (en) * | 2018-10-26 | 2021-01-15 | 日照市妇女儿童医院(日照市妇幼保健院、日照市妇幼保健计划生育服务中心) | Medical care dispensing device |
| CN109481744B (en) * | 2018-11-01 | 2021-02-12 | 吉林大学第一医院 | Portable sterile liquid suction device for medical treatment and use method |
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