CN211927694U - Analyzer and reagent cup thereof - Google Patents

Abstract

The utility model discloses an analysis appearance and reagent cup thereof, reagent cup include integrated into one piece's notes liquid section, light inspection section and flowing back section, and it is used for receiving reagent to annotate the liquid section, is equipped with the reaction chamber in the light inspection section, and the flowing back section is equipped with the leakage fluid dram that runs through, and leakage fluid dram and reaction chamber intercommunication are annotated liquid section, light inspection section and flowing back section and are in proper order smooth transitional coupling. The reagent cup in this embodiment can adopt the integrative injection moulding of plastic material, through annotating liquid section, the light with the reagent cup examine section and flowing back section in proper order smooth transitional coupling, can reduce the junction of annotating liquid section and light and examining the section to and the quantity of the die joint of the junction of light examination section and flowing back section, make the simple structure of mould with this, and then reduced the processing complexity of mould, with this reduction reagent cup's manufacturing cost.

Description

Analyzer and reagent cup thereof

Technical Field

The utility model relates to the technical field of medical equipment, concretely relates to analyzer and reagent cup thereof.

Background

A specific protein analyzer is an analytical instrument for measuring the content of specific proteins in human body fluids. The principle of the specific protein analyzer is that the turbidity of a solution obtained after a sample and a reagent react in a reagent cup is measured by utilizing the principle of laser scattering turbidimetric measurement to determine the content of specific protein in the sample, and the content of the specific protein reflects the corresponding state of the body of a patient, so that effective reference data is provided for diagnosis of doctors.

The reagent cup that specific protein analysis appearance in the existing market used is single cup structure basically, and semi-automatic specific protein analysis appearance uses mostly disposable reagent cup, and the reagent cup is non-used repeatedly, and needs manual application of sample and application of sample agent, complex operation. Full-automatic specific protein analyzer reagent cup operation is comparatively simple, but need use puddler or magnetic bead mixing mode mixing, leads to the structure complicacy, and the reagent cup is mostly bottom enclosed construction, produces raffinate cross contamination easily.

SUMMERY OF THE UTILITY MODEL

The utility model provides an analyzer and reagent cup thereof to solve the technical problem that reagent cup structure is complicated among the prior art, produces raffinate cross contamination easily.

In order to solve the technical problem, the utility model discloses a technical scheme be: the reagent cup comprises an injection section, a light detection section and a liquid discharge section which are integrally formed, wherein the injection section is used for receiving a reagent, a reaction cavity is arranged in the light detection section, the liquid discharge section is provided with a liquid discharge port which penetrates through the liquid discharge port, the liquid discharge port is communicated with the reaction cavity, and the injection section, the light detection section and the liquid discharge section are sequentially in smooth transition connection.

According to an embodiment of the invention, both the inner surface and the outer surface of the reagent cup are smooth surfaces.

According to the utility model discloses an embodiment, at the perpendicular to in the direction of the axis of reagent cup, the outer cross sectional dimension who annotates the liquid section is greater than the outer cross sectional dimension of optical inspection section, just the outer cross sectional dimension of optical inspection section is greater than the outer cross sectional dimension of flowing back section.

According to an embodiment of the present invention, the angle between the outer surface of the light inspection section and the axis of the reagent cup is 0.5-3 °.

According to an embodiment of the present invention, the outer surface of the optical inspection section and the included angle of the central axis of the reagent cup are 0.75 °.

According to the utility model discloses an embodiment, be equipped with the recess on the lateral wall of optical inspection section.

According to the utility model discloses an embodiment, the quantity of recess is two, two the recess set up in the relative both sides of optical inspection section.

According to the utility model discloses an embodiment, at the perpendicular to in the direction of the axis of reagent cup, the outer cross sectional shape of annotating the liquid section is circular, the outer cross sectional shape of optical inspection section is the rectangle, the outer cross sectional shape of flowing back section is circular.

According to the utility model discloses an embodiment, the reagent cup still includes location portion, location portion set up in on the surface of reagent cup, and be located the light examine the section with the juncture of flowing back section.

For solving the technical problem, the utility model discloses a another technical scheme is: the analyzer comprises a laser module, a laser signal receiver and the reagent cup, wherein the laser module and the laser signal receiver are respectively arranged on two opposite sides of the reagent cup, the laser module is used for generating laser, and the laser signal receiver is used for receiving and analyzing the laser passing through the reagent cup.

The utility model has the advantages that: be different from prior art's condition, the reagent cup in this embodiment can adopt the integrative injection moulding of plastic material, through annotating liquid section, light with the reagent cup examine the section and flowing back the section in proper order smooth transitional coupling, can reduce the junction of annotating liquid section and light and examining the section to and the quantity of the die joint of the junction of light examination section and flowing back section, make the simple structure of mould with this, and then reduced the processing complexity of mould, with this manufacturing cost who reduces the reagent cup.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained without inventive work, wherein:

fig. 1 is a schematic perspective view of an analyzer according to an embodiment of the present invention;

FIG. 2 is a schematic perspective view of a reagent cup according to an embodiment of the present invention;

FIG. 3 is a schematic cross-sectional view of the reagent cup of FIG. 2;

FIG. 4 is a schematic plan view of the reagent cup of FIG. 2;

FIG. 5 is a schematic bottom view of the reagent cup of FIG. 2;

fig. 6 is another sectional view of the reagent cup of fig. 2.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.

Referring to fig. 1, fig. 1 is a schematic perspective view of an analyzer according to an embodiment of the present invention. An embodiment of the present invention provides an analyzer 100, wherein the analyzer 100 comprises a laser module 10, a laser signal receiver 20 and a reagent cup 30. The laser module 10 and the laser signal receiver 20 are respectively arranged at two opposite sides of the reagent cup 30, the laser module 10 is used for generating laser, and the laser signal receiver 20 is used for receiving and analyzing the laser passing through the reagent cup 30.

Specifically, the reaction solution after the reaction is contained in the reagent cup 30, the laser spot generated by the laser module 10 is emitted into the reagent cup 30 from one side surface of the reagent cup 30, the reaction solution passing through different concentrations can generate scattered light with different intensities, and the laser signal receiver 20 receives the scattered light and performs signal processing, so that the specific protein can be accurately detected.

Wherein, laser module 10 and laser signal receiver 20 can adopt the structure in the correlation technique, the embodiment of the utility model does not specifically limit.

Referring to fig. 2 and 3, fig. 2 is a schematic perspective view of a reagent cup according to an embodiment of the present invention, and fig. 3 is a schematic sectional view of the reagent cup of fig. 2. In this embodiment, the reagent cup 30 comprises an injection section 31, a light detection section 33 and a liquid discharge section 35 which are integrally formed. The liquid injection section 31 is used for receiving reagents, a reaction cavity 332 is arranged in the optical inspection section 33, a liquid discharge port 352 penetrating through the liquid discharge section 35 is arranged in the liquid discharge section 35, the liquid discharge port 352 is communicated with the reaction cavity 332, and the liquid injection section 31, the optical inspection section 33 and the liquid discharge section 35 are sequentially in smooth transition connection.

Wherein, the reagent cup 30 in this embodiment can adopt the integrative injection moulding of plastic material, through annotating liquid section 31, the smooth transitional coupling in proper order of examining section 33 and flowing back section 35 with reagent cup 30, can reduce the junction of annotating liquid section 31 and the smooth section 33 of examining to and the quantity of the die joint of the junction of the smooth section 33 of examining and flowing back section 35, with this make the simple structure of mould, and then reduced the processing complexity of mould, with this reduction reagent cup 30's manufacturing cost.

Specifically, in the present embodiment, the reagent and the sample are injected into the injection section 31, and the reagent and the sample are introduced into the reaction chamber 332 of the light detection section 33 along the injection section 31 under the action of gravity. A bubble generator (not shown) is connected to the lower end of the liquid discharge section 35, and bubbles are blown into the reaction chamber 332 from the liquid discharge port 352 to mix the sample and the reagent. The mode of mixing the bubbles at the bottom can not only play a good mixing effect, but also avoid the scratch on the inner wall of the reaction cavity 332 caused by the mixing mode of the stirring rod or the magnetic beads, thereby prolonging the service life of the reagent cup 30. In addition, the liquid outlet 352 is formed in the bottom of the reagent cup 30, so that residual liquid after reaction can be discharged conveniently, and the inner cavity of the reagent cup 30 can be cleaned conveniently, so that residual liquid adhesion is reduced, the cleanliness of the inner cavity of the reagent cup 30 is improved, and the detection precision of the analyzer 100 is improved.

Further, it may be provided that both the inner and the outer surface of the reagent cup 30 are smooth surfaces. Where smooth surfaces are defined as surfaces that are joined in smooth transition without edges at the interface of adjacent surfaces. All set up to smooth surface through the internal surface with reagent cup 30 and surface, the quantity of reduction die joint that can be very big not only makes the simple structure of mould, low in production cost, also can be convenient for reagent cup 30 demolding moreover to promote reagent cup 30's yields.

Alternatively, in another embodiment, only the inner surface of the reagent cup 30 may be provided as a smooth surface, or only the outer surface of the reagent cup 30 may be provided as a smooth surface, which is not particularly limited by the embodiment of the present invention.

Further, as shown in FIG. 3, in the direction perpendicular to the central axis of the reagent cup 30, the outer cross-sectional dimension of the injection section 31 is larger than that of the optical inspection section 33, and the outer cross-sectional dimension of the optical inspection section 33 is larger than that of the liquid discharge section 35.

Wherein, in this embodiment, the reagent cups 30 are of an axisymmetric structure, so as to facilitate the production, processing and mounting of the reagent cups 30. The middle axis of the reagent cup 30 is the symmetry axis of the reagent cup 30, i.e. the dash-dotted line shown in fig. 3. In the direction perpendicular to the central axis of the reagent cup 30, the outer cross-sectional dimension of the injection section 31 refers to the dimension of the area enclosed by the outer circumferential surface of the injection section 31, the outer cross-sectional dimension of the optical inspection section 33 refers to the dimension of the area enclosed by the outer circumferential surface of the optical inspection section 33, and the outer cross-sectional dimension of the liquid discharge section 35 refers to the dimension of the area enclosed by the outer circumferential surface of the liquid discharge section 35. In this embodiment, by setting the outer cross-sectional dimension of the liquid injection section 31 to be larger than that of the optical inspection section 33, the liquid injection section 31 with a larger size can be conveniently formed, so as to facilitate liquid injection. The liquid discharge section 35 is smaller than the light detection section 33, so that residual liquid can be discharged conveniently.

Alternatively, in the present embodiment, the outer cross-sectional dimension of the liquid injection section 31 is gradually reduced in a direction approaching the light detection section 33, that is, in a direction D shown in the figure, the outer cross-sectional dimension of the liquid injection section 31 is gradually reduced to form the liquid injection section 31 in a horn shape. Through the liquid injection section 31 that forms loudspeaker form, not only can be convenient for annotate the liquid, the horn mouth structure also can be convenient for sample and reagent from the inclined plane leading-in reaction chamber 332 in, reduces the possibility that sample and reagent attached at the notes liquid section 31 inside wall.

Alternatively, in another embodiment, the outer cross-sectional dimension of the injection section 31 at the portion far from the optical inspection section 33 can be kept constant, while the outer cross-sectional dimension of the injection section 31 at the portion near the optical inspection section 33 is gradually reduced.

Further, it may be provided that the outer cross-sectional dimension of the liquid discharge section 35 is gradually reduced in a direction away from the light inspection section 33, that is, in a direction D shown in the drawing, the outer cross-sectional dimension of the liquid discharge section 35 is gradually reduced to form a trumpet-shaped liquid discharge section 35. Through the formation of the horn-shaped liquid discharge section 35, liquid discharge can be facilitated, and the horn-shaped structure can facilitate the introduction of residual liquid into the liquid discharge port 352, so that the possibility that the residual liquid is attached to the inner side wall of the liquid discharge section 35 is reduced.

Alternatively, in another embodiment, the liquid discharge section 35 may be configured to have a constant outer cross-sectional dimension at a portion away from the light detection section 33 for connection with the bubble generation device, while the liquid discharge section 35 may have a gradually decreasing outer cross-sectional dimension at a portion close to the light detection section 33.

Further, in this embodiment, the outer surface of the light inspection section 33 may be arranged at an angle of 0.5-3 degrees to the central axis of the reagent cup 30. In particular, as shown in fig. 3, the outer cross-sectional dimension of the light detecting section 33 decreases gradually in a direction approaching the liquid discharge section 35, i.e. in a direction D as shown in the figure, the outer cross-sectional dimension of the light detecting section 33 decreases gradually such that the outer surface of the light detecting section 33 makes an angle of 0.5-3 with the centre axis of the reagent cup 30. The outer surface of the optical inspection section 33 is inclined relative to the central axis of the reagent cup 30, so that the reagent cup can be conveniently demoulded, and the yield of the reagent cup 30 is further improved.

In this embodiment, the outer surface of the light inspection section 33 may be arranged at an angle of 0.75 ° to the central axis of the reagent cup 30. Or, in other optional embodiments, the included angle between the outer surface of the light detection section 33 and the central axis of the reagent cup 30 may be set to be 0.5 °, 1 °, 1.5 °, 2 °, 2.5 ° or 3 °, and the embodiment of the present invention is not limited specifically.

Further, as shown in fig. 2 and 4, fig. 4 is a schematic plan view of the reagent cup of fig. 2. In this embodiment, a groove 334 is provided on the outer sidewall of the light inspection section 33. The laser light for detection is irradiated to the position of the light detection section 33 corresponding to the groove 334. Through set up the recess 334 that corresponds with the laser on the lateral wall of light inspection section 33, can avoid packing transportation or change the in-process of reagent cup 30 and take place the fish tail, and produce the influence to the incidence of laser, from this, promote the detection precision of analysis appearance 100.

In the embodiment, the number of the grooves 334 is two, and the two grooves 334 are disposed on two opposite sides of the optical inspection section 33, so as to avoid scratching in the process of packaging, transporting or replacing the reagent cup 30, and influence the incidence and the emergence of laser light, thereby improving the detection accuracy of the analyzer 100.

Alternatively, in other alternative embodiments, the other side wall of the light detecting section 33 may be provided with a groove 334 to protect the outer side wall of the light detecting section 33.

Alternatively, as shown in Figs. 2 and 5, fig. 5 is a schematic view of the reagent cup of fig. 2 in a bottom view. In the direction perpendicular to the central axis of the reagent cup 30, the outer cross-sectional shape of the injection section 31 is circular, the outer cross-sectional shape of the optical inspection section 33 is rectangular, and the outer cross-sectional shape of the liquid discharge section 35 is circular. The outer section of the liquid injection section 31 is circular, so that the liquid injection section 31 can be conveniently molded; the incidence and the emission of the laser can be facilitated by setting the outer sectional shape of the optical inspection section 33 to be rectangular; by providing the liquid discharge section 35 with a circular outer cross-sectional shape, the connection of the liquid discharge section 35 to the bubble generating means can be facilitated.

Or, in other optional embodiments, the cross-sectional shapes of the liquid injection section 31, the optical inspection section 33 and the liquid discharge section 35 can also be flexibly set according to installation or use requirements, and the embodiment of the present invention is not particularly limited.

Further, as shown in Figs. 2 and 6, fig. 6 is another schematic sectional structure view of the reagent cup of fig. 2. The reagent cup 30 further comprises a positioning portion 37, which positioning portion 37 is arranged on the outer surface of the reagent cup 30 and is located at the interface of the light detection section 33 and the liquid discharge section 35. By providing the positioning portion 37 at a side of the reagent cup 30 close to the liquid discharge section 35, positioning and mounting of the reagent cup 30 can be facilitated, so that the groove 334 of the reagent cup 30 is located between the laser module 10 and the optical path of the laser signal receiver 20, thereby facilitating detection.

Alternatively, in this embodiment, the number of positioning portions 37 is two, and two positioning portions 37 are provided on opposite sides of the reagent cup 30, respectively, to improve the positioning accuracy. Alternatively, in another embodiment, the number of positioning portions 37 may also be one, in order to reduce the complexity of the manufacture of the reagent cups 30. Alternatively, in a further embodiment, the number of detents 37 may also be three, three detents 37 being provided at intervals around the circumference of the reagent cup 30 to provide a uniform force on the reagent cup 30. Alternatively, in other optional embodiments, the number of the positioning portions 37 may also be four, five, and the like, and the embodiment of the present invention is not particularly limited.

Optionally, in the present embodiment, the positioning portion 37 and the reagent cup 30 are integrally formed, for example, the positioning portion 37 and the reagent cup 30 can be integrally injection molded by injection molding, so as to improve the connection strength between the reagent cup 30 and the positioning portion 37, simplify the production process, and improve the production efficiency. Alternatively, in other optional embodiments, the positioning portion 37 and the reagent cup 30 may be detachably connected, or connected by welding, bonding, or the like, and the embodiment of the present invention is not limited in particular.

This example describes the use of the reagent cups in this example, taking protein analysis as an example. Referring to FIGS. 1 to 6, the specific protein analysis and detection process using the reagent cup 30 of the present embodiment is as follows:

first, a set amount of reagent is injected into the reagent cup 30 through the tubing, and the sampling needle adds the collected sample to the reagent cup 30. Then, air bubbles are injected from the liquid outlet 352 at the bottom of the reagent cup 30 to mix the sample and the reagent sufficiently for pretreatment. The antiserum is sucked by the sampling needle and injected into the reagent cup 30, and air bubbles are continuously injected from the liquid outlet 352 at the bottom of the reagent cup 30 so as to uniformly mix and react the pretreated sample with the antiserum.

Then, the laser module 10 emits laser light, which passes through the groove 334 of the reagent cup 30, and after passing through the reaction liquid in the reaction chamber 332, forms scattered light through a certain angle of refraction, and the scattered light is emitted into the laser signal receiver 20. The laser signal receiver 20 obtains the concentration of the specific protein through signal and algorithm processing.

Finally, the waste liquid after detection is discharged from the liquid outlet 352 at the bottom of the reagent cup 30, the cleaning liquid is injected into the reagent cup 30 from the pipeline for inner wall cleaning, and the cleaned reagent cup 30 can continue to be used for the next sample test, thereby realizing the reutilization until the reagent cup 30 does not meet the use requirement.

In summary, those skilled in the art will readily understand that the reagent cup 30 in the present embodiment can be integrally injection molded by plastic material, and the number of parting surfaces at the joint of the injection section 31 and the optical inspection section 33 and the joint of the optical inspection section 33 and the liquid discharge section 35 can be reduced by sequentially and smoothly transitionally connecting the injection section 31, the optical inspection section 33 and the liquid discharge section 35 of the reagent cup 30, so that the structure of the mold is simple, the processing complexity of the mold is reduced, and the production cost of the reagent cup 30 is reduced.

The above only is the embodiment of the present invention, not limiting the scope of the present invention, all the equivalent structures or equivalent processes of the present invention are used in the specification and the attached drawings, or directly or indirectly applied to other related technical fields, and the same principle is included in the protection scope of the present invention.

Claims (10)

1. A reagent cup is characterized by comprising an injection section, an optical inspection section and a liquid discharge section which are integrally formed, wherein the injection section is used for receiving a reagent, a reaction cavity is arranged in the optical inspection section, the liquid discharge section is provided with a liquid discharge port which penetrates through the liquid discharge port, the liquid discharge port is communicated with the reaction cavity, and the injection section, the optical inspection section and the liquid discharge section are sequentially in smooth transition connection.

2. Reagent cup according to claim 1, characterized in that both the inner and the outer surface of the reagent cup are smooth surfaces.

3. Reagent cup according to claim 1, wherein the injection section has an outer cross-sectional dimension which is larger than an outer cross-sectional dimension of the light inspection section and the light inspection section has an outer cross-sectional dimension which is larger than an outer cross-sectional dimension of the liquid discharge section in a direction perpendicular to the middle axis of the reagent cup.

4. A reagent cup according to claim 3, wherein the outer surface of the photometric segment forms an angle with the central axis of the reagent cup of between 0.5 ° and 3 °.

5. Reagent cup according to claim 4, wherein the outer surface of the photometric segment forms an angle of 0.75 ° with the central axis of the reagent cup.

6. Reagent cup according to claim 1, wherein the outer side wall of the light-detecting section is provided with a groove.

7. Reagent cup according to claim 6, wherein the number of recesses is two, two recesses being arranged on opposite sides of the light detection section.

8. Reagent cup according to claim 1, wherein the injection section has a circular outer cross-sectional shape, the light inspection section has a rectangular outer cross-sectional shape and the liquid discharge section has a circular outer cross-sectional shape in a direction perpendicular to the central axis of the reagent cup.

9. Reagent cup according to claim 1, characterized in that it further comprises a positioning portion provided on the outer surface of the reagent cup at the interface of the light detection section and the liquid discharge section.

10. An analyzer, comprising a laser module, a laser signal receiver and a reagent cup according to any of claims 1-9, wherein the laser module and the laser signal receiver are respectively disposed at two opposite sides of the reagent cup, the laser module is used for generating laser, and the laser signal receiver is used for receiving and analyzing the laser after passing through the reagent cup.

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