CN216350758U - Kit and assembly seat - Google Patents
Kit and assembly seat Download PDFInfo
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- CN216350758U CN216350758U CN202120322820.8U CN202120322820U CN216350758U CN 216350758 U CN216350758 U CN 216350758U CN 202120322820 U CN202120322820 U CN 202120322820U CN 216350758 U CN216350758 U CN 216350758U
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Abstract
The application provides a kit and an assembly seat, wherein the assembly seat comprises an assembly cylinder and a rear pool electrode, the assembly cylinder is provided with an axial drainage cavity and a radial liquid outlet groove which are communicated with each other, and the radial liquid outlet groove is used for discharging gas or liquid in the axial drainage cavity; the rear pool electrode is connected with the assembling cylinder and extends to the axial drainage cavity. The application provides a kit novel structure, low cost can regard as disposable consumptive material product, need not to adopt can rinse the expensive material of use repeatedly.
Description
Technical Field
The application relates to the technical field of medical instruments, in particular to a microporous sheet, a kit, an assembly seat and a sample detection device.
Background
The hemocyte analyzer is called hemocyte analyzer, blood-ball meter, blood-cell counter, etc. and is one of the widely used instruments for clinical examination in hospital.
Most parts of the components in the conventional blood cell analyzer belong to a cleaning system, because the use trace of the previous blood sample must be cleaned before the next blood sample detection. The whole cleaning system is complex in structure and multiple in parts, and a large amount of reagents are needed in the cleaning process, so that the cleaning system occupies a long time.
Compared with the traditional blood cell analyzer, the POCT blood cell analyzer is greatly simplified in instrument components, and the POCT blood cell analyzer can completely remove components related to a cleaning liquid path in the traditional blood analysis, so that the complexity and the production cost of a product are greatly reduced.
However, some of the conventional POCT blood cell analyzers have too simple functions, some have complicated structures, some have low automation degrees, and some have high costs.
SUMMERY OF THE UTILITY MODEL
The present application provides a microchip, a kit, a mounting base, and a sample detection device, which at least partially solve the above technical problems.
In order to solve the technical problem, the application adopts a technical scheme that: providing a mount, the mount comprising:
the assembling cylinder is provided with an axial drainage cavity and a radial liquid outlet groove which are communicated with each other, and the radial liquid outlet groove is used for discharging gas or liquid in the axial drainage cavity;
a rear cell electrode connected with the assembly cylinder and extending to the axial drainage cavity
The beneficial effect of this application is: different from the prior art, the microporous sheet, the kit, the assembly seat and the sample detection device provided by the application have the advantages of novel structure and low cost, can be used as a disposable consumable product, and do not need to adopt expensive materials which can be repeatedly cleaned and used.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, it is obvious that the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without inventive efforts, wherein:
FIG. 1 is a schematic perspective view of a microporous sheet according to an embodiment of the present disclosure;
FIG. 2 is a schematic cross-sectional structure of the microporous sheet shown in FIG. 1;
FIG. 3 is a schematic view of an exploded view of a kit according to an embodiment of the present disclosure;
FIG. 4 is a schematic diagram of an exploded view from another perspective of a kit according to an embodiment of the present application;
FIG. 5 is a schematic cross-sectional view of a viewing angle of a kit according to an embodiment of the present disclosure;
fig. 6 is a schematic cross-sectional view of another perspective of a kit according to an embodiment of the present disclosure.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
It should be noted that if directional indications (such as up, down, left, right, front, and back … …) are referred to in the embodiments of the present application, the directional indications are only used to explain the relative positional relationship between the components, the movement situation, and the like in a specific posture (as shown in the drawings), and if the specific posture is changed, the directional indications are changed accordingly.
In addition, if there is a description of "first", "second", etc. in the embodiments of the present application, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present application.
In a first embodiment, referring to fig. 1 and 2 together, the embodiment of the present invention provides a microporous sheet 170, the microporous sheet 170 includes a sheet 171, the sheet 171 is provided with micropores 172 allowing cells to pass through one by one, the micropores 172 may have different specifications according to cells with different particle sizes, the sheet 171 is a plastic sheet or a ceramic sheet, the mechanical strength of the plastic sheet or the ceramic sheet is relatively weak, the sheet 171 of the embodiment of the present invention is further provided with a reinforcing part 173 to ensure the mechanical strength of the microporous sheet 170, and at the same time, the microporous sheet 170 is convenient to install, when the microporous sheet 170 is installed, the micropores 172 are not easily polluted or worn by contact, the material cost of the plastic sheet or the ceramic sheet is relatively cheap, and the microporous sheet can be used as a disposable product without using expensive materials capable of being repeatedly cleaned and used.
The reinforcement 173 may be disposed proximate to an edge of the sheet 171. the reinforcement 173 may be configured as a torus, which may be a continuous integral torus or a torus formed by a plurality of hulls around the torus, with or without an outer edge of the torus coinciding with an outer edge of the sheet 171.
The convex ring is connected to the first surface 175 and/or the second surface 176 of the sheet 171 by a vertical surface, an inclined surface or an arc surface, wherein the inclined surface or the arc surface can further reduce sample residue and improve detection accuracy.
The first surface 175 of the sheet 171 is provided with a concave drainage part 174 at the periphery of the micro-holes 172, and the concave drainage part 174 may be spherical or conical.
The ratio of the thickness of the protruding ring to the thickness of the sheet body 171 is 0.2-2, preferably, the ratio of the width of the protruding ring to the radius of the sheet body 171 is less than or equal to 1, if the thickness of the protruding ring is too small, the protruding ring cannot play a good role in reinforcing mechanical strength, if the thickness of the protruding ring is too large, materials are wasted, and if the thickness of the protruding ring is too large, the wall thickness of the micropores 172 of the microporous sheet 170 is also difficult to control, which results in a complex manufacturing process. The ratio of the width of the convex ring to the radius of the sheet 171 is 0.2-0.8, and similarly, if the width of the convex ring is too small, the convex ring cannot provide a good mechanical strength reinforcing effect, and if the width of the convex ring is too large, the wall thickness of the micropores 172 of the microporous sheet 170 is difficult to control, which results in a complicated manufacturing process, and if the width of the convex ring is too large (for example, close to the radius of the sheet 171), the axial channels of the micropores 172 may be lengthened, which further causes the backflow of the sample particles to be detected, which may affect the accuracy of the detection when the cells pass through.
The embodiment provides a microporous sheet 170, which can improve the mechanical strength of the microporous sheet 170 by providing a reinforcing part 173, and prevent the microporous sheet 170 made of plastic material or ceramic material from being easily deformed when being assembled, and also provides a kit including the microporous sheet 170, and the specific structure of the kit is referred to below.
Referring to fig. 1 to 6, a kit according to an embodiment of the present invention includes a case 100, a mounting base 160, and a microporous sheet 170.
The cartridge 100 includes a front cell 120, the cartridge 100 has a front cell electrode 121 corresponding to the front cell 120, and the front cell 120 may be provided with two groups, which are respectively used for performing WBC (white blood cell) detection and RBC (red blood cell) detection in a matching manner.
As shown in fig. 6, the mounting base 160 is connected to the box 100, and the mounting base 160 has an axial drainage chamber 167 (the axial drainage chamber 167 may also be referred to as a rear cell), and a rear cell electrode 165 extending to the axial drainage chamber 167.
As shown in fig. 1, 2 and 6, the microporous sheet 170 is provided with micropores 172 allowing cells to pass through one by one, the microporous sheet 170 is disposed between the front cell 120 and the axial drainage chamber 167, the front cell 120 and the axial drainage chamber 167 are communicated through the micropores 172, and the front cell electrode 121 and the rear cell electrode 165 are respectively spaced at both sides of the microporous sheet 170.
The mounting socket 160 is detachably coupled to the cartridge body 100.
In an embodiment, the front cell electrode 121 may be integrally injection molded with the case 100 or detachably connected thereto. The rear cell electrode 165 and the mounting seat 160 can be integrally injection-molded or detachably connected, the front cell electrode 121 and/or the rear cell electrode 165 are columnar electrodes, and the length of the rear cell electrode 165 is greater than or equal to that of the front cell electrode 121. The microporous sheet 170 may be integrally injection molded or removably attached to the case 100, or the microporous sheet 170 may be integrally injection molded or removably attached to the mounting cup 160.
The box body 100 is provided with a mounting cavity 130, and the assembling seat 160 is in snap fit, threaded fit, interference fit, laser welding fit or bonding fit with the mounting cavity 130.
The box body 100 and/or the assembly seat 160 are plastic bodies, the front cell electrode 121 is embedded in the box body 100 and is flush, protruded or recessed on the outer surface of the box body 100, the rear cell electrode 165 is embedded in the assembly seat 160 and is flush, protruded or recessed on the outer end surface of the assembly seat 160, the outer ends (i.e., two ends far away from each other) of the front cell electrode 121 and the rear cell electrode 165 are used for connecting working voltage, the inner ends (i.e., two ends close to each other) of the front cell electrode 121 and the rear cell electrode 165 are in contact with a sample liquid to be detected, and the axial drainage cavity 167 is filled with the sample liquid to be detected during detection.
The kit further includes an inner gasket 164, where the inner gasket 164 is disposed between the microporous sheet 170 and the anterior chamber 120, and in particular, between the first surface 175 of the microporous sheet 170 and the anterior chamber 120, so that the sample fluid to be tested in the anterior chamber 120 can only enter the axial drainage lumen 167 through the micropores 172.
The reagent vessel further comprises an outer sealing ring 166, the outer sealing ring 166 being arranged between the mounting socket 160 and the free end of the mounting chamber 130.
In one embodiment, the inner seal ring 164, the outer seal ring 166, the microporous sheet 170, and the mounting socket 160 are separate structural components.
In another embodiment, the inner seal ring 164, the outer seal ring 166, the microporous sheet 170 and the mounting seat 160 may be an integral structure to reduce the number of mounting parts, the difficulty of mounting, and the time of mounting, wherein the inner seal ring 164 and the outer seal ring 166 may be formed by injection molding using a relatively soft plastic material by a two-shot molding process.
In another embodiment, the inner seal ring 164, the outer seal ring 166, and the mounting seat 160 are an integral structure, and the microporous sheet 170 is detachably connected to the integral structure, so that the number of mounting components can be reduced, and the manufacturing accuracy and the yield of the microporous sheet 170 can be ensured. Wherein the inner seal ring 164 has a flexibility such that when the microporous sheet 170 is assembled with the integral structure, the inner seal ring 164 can be assembled behind the inner seal ring 164 by the flexibility of the inner seal ring 164, and the inner seal ring 164 still seals against the first surface 175 of the microporous sheet 170.
The kit provided by the embodiment has a novel structure and is convenient to assemble.
In a third embodiment, referring to fig. 1-6, the present embodiment provides a mounting base 160, wherein the mounting base 160 includes a mounting cylinder 168 and a rear cell electrode 165.
The mounting cylinder 168 is provided with an axial drainage cavity 167 and a radial liquid outlet slot 1611 (see fig. 4) which are communicated with each other, wherein the radial liquid outlet slot 1611 is used for discharging gas or liquid in the axial drainage cavity 167; the rear cell electrode 165 is connected to the mounting cylinder 168 and extends into the axial drainage lumen 167.
A first preset distance is formed between the inner end of the radial liquid outlet groove 1611 and the inner end of the assembly cylinder 168, a second preset distance is formed between the inner end of the rear cell electrode 165 and the inner end of the assembly cylinder 168, and the first preset distance is smaller than or equal to the second preset distance. When first preset distance is less than second preset distance, the bubble in axial drainage chamber 167 discharges axial drainage chamber 167 more easily, if remain the bubble in axial drainage chamber 167, can influence and detect the precision. The inner end is referred to the inside of the cartridge 100, and when the forebay 120 is referred to, the end pointing to the forebay is the inner end, and the end away from the forebay 120 is the outer end, for example, the inner end of the mounting cavity 130 is communicated with the forebay 120 through the via hole 132, and the outer end of the mounting cavity 130 is an open end for receiving the mounting seat 160.
The axial length of the radial exit slot 1611 in the axial drainage lumen 167 is greater than or equal to the length of the rear cell electrode 165 that extends into the axial drainage lumen 167. Wherein the inner end of rear cell electrode 165 may or may not extend into axial drainage lumen 167, i.e., the inner end of rear cell electrode 165 may protrude, be flush, or be recessed at the bottom surface of axial drainage lumen 167.
Further, the outer surface of the mounting cylinder 168 is provided with a recessed area communicated with the radial liquid outlet groove 1611 to form a flow guide groove 1612, the flow guide groove 1612 can enable gas or liquid in the axial flow guide cavity 167 to flow away through the flow guide groove 1612 obliquely above after coming out of the radial liquid outlet groove 1611 directly above, so that the two mounting seats 160 can share one pressure action pool 140 communicated with the two mounting seats 160, and the pressure action pool 140 is communicated with the mounting cavity 130 through a through hole 133 (which can be in a fan shape as shown in fig. 5), and further communicated with the axial flow guide cavity 167 sequentially through the flow guide groove 1612 and the radial liquid outlet groove 1611.
The inner end of the fitting cylinder 168 is provided with a micro-porous sheet 170 for allowing cells to pass therethrough one by one, and the specific structure of the micro-porous sheet 170 can be referred to the previous embodiment.
The distance from the inner end of the rear cell electrode 165 to the microporous sheet 170 is a third preset distance which is 0.2-2 times the axial length of the axial drainage cavity 167, and experiments prove that in the range, better signal precision can be obtained during impedance detection.
The inner end of the mounting cylinder 168 is provided with a sinking platform 1613, the microporous sheet 170 is matched and connected with the sinking platform 1613, and the reinforcing part 173 of the microporous sheet 170 is abutted against the sinking platform 1613.
As shown in fig. 4, the assembly cylinder 168 includes a rear cylinder 161, an end plate 162 and an outer cylinder 163 which are integrally connected, the rear cylinder 161 is provided with an axial drainage cavity 167 and a radial liquid outlet slot 1611, the end plate 162 radially connects the rear cylinder 161 and the outer cylinder 163, and the outer cylinder 163 is sleeved on the outer periphery of the rear cylinder 161 at intervals.
The radial liquid outlet slot 1611 may be circular, kidney-shaped or rectangular.
The application also provides a kit, which comprises a kit body 100 and the assembling seat 160, wherein the kit body 100 is provided with a front pool 120 and a mounting cavity 130 which are communicated, an assembling cylinder 168 is connected with the mounting cavity 130, and the front pool 120 is communicated with an axial drainage cavity 167 through micropores 172 of a microporous sheet 170.
The reagent kit and the assembly seat 160 thereof provided by the embodiment can conveniently discharge the bubbles in the assembly cylinder 168 by limiting the distance between the inner end of the radial liquid outlet tank 1611 and the inner end of the rear cell electrode 165 and the inner end of the assembly cylinder 168, and prevent the bubbles from remaining in the assembly cylinder 168 to influence the detection precision in the impedance method detection.
In a fourth embodiment, referring to fig. 1 to 6, the present embodiment provides a mounting base 160, the mounting base 160 includes a mounting cylinder 168 and a rear cell electrode 165, the rear cell electrode 165 is a cylindrical electrode, and the rear cell electrode 165 is connected to the mounting cylinder 168.
The assembling barrel 168 is provided with a radial liquid outlet groove 1611 and a buckling part 1631, the buckling part 1631 and the radial liquid outlet groove 1611 are arranged in an aligned mode, the buckling part 1631 can be a buckling hole or a buckling lug, correspondingly, the outer surface of the mounting cavity 130 is provided with a buckling block 131 corresponding to the buckling hole, and the opening directions of one of the buckling parts 1631 and the radial liquid outlet groove 1611 are consistent and arranged in an aligned mode, so that the die can be conveniently pulled out from the same direction during injection molding of the die.
The assembly barrel 168 is provided with an axial drainage cavity 167, the axial drainage cavity 167 is communicated with the radial liquid outlet groove 1611, and the rear pool electrode 165 extends to the axial drainage cavity 167.
The rear cell electrode 165 may be embedded in the mounting seat 160 by injection molding and flush, protruded or recessed on the outer end surface of the mounting seat 160.
In the embodiment of the present application, the assembly cylinder 168 includes a rear cylinder 161, an end plate 162 and an outer cylinder 163 which are integrally connected, the rear cylinder 161 is provided with a radial liquid outlet slot 1611 and an axial drainage cavity 167, and the end plate 162 radially connects the rear cylinder 161 and the outer cylinder 163.
The outer barrel 163 may extend axially with a plurality of positioning protrusions 1632 arranged at intervals, and the fastening portion 1631 is arranged corresponding to the positioning protrusions 1632.
A first preset distance is formed between the inner end of the radial liquid outlet groove 1611 and the inner end of the assembly cylinder 168, a second preset distance is formed between the inner end of the rear cell electrode 165 and the inner end of the assembly cylinder 168, and the first preset distance is smaller than or equal to the second preset distance.
The rear cell electrode 165 and the mounting cylinder 168 may be integrally formed or removably attached.
The inner end of the rear cell cylinder 161 is provided with a sink 1613 for assembling the micro-porous sheet 170 allowing cells to pass therethrough one by one.
The application also provides a kit, which comprises a kit body 100 and the assembly seat 160, wherein the kit body 100 is provided with a front pool 120 and a mounting cavity 130 which are communicated, the assembly cylinder 168 of the assembly seat 160 is connected with the mounting cavity 130, and the front pool 120 is communicated with the axial drainage cavity 167 through micropores 172 of a microporous sheet 170.
The reagent kit and the assembly seat 160 thereof provided by this embodiment can facilitate the mold drawing operation after the mold forming by aligning the radial liquid outlet slot 1611 and the fastening part 1631.
In a fifth embodiment, referring to fig. 1-6, the present invention provides a mounting base 160, wherein the mounting base 160 includes a mounting cylinder 168 and a rear cell electrode 165.
The assembling cylinder 168 is provided with an axial drainage cavity 167 and a radial liquid outlet groove 1611 which are communicated with each other, a recessed area communicated with the radial liquid outlet groove 1611 is arranged on the outer surface of the assembling cylinder 168 to form a flow guide groove 1612, the flow guide groove 1612 can enable gas or liquid in the axial drainage cavity 167 to flow out through the radial liquid outlet groove 1611 (for example, right above) and then flow to the pressure action pool 140 smoothly through the flow guide groove 1612 (for example, obliquely above), so that the two assembling seats 160 can share one pressure action pool 140 communicated with the two assembling seats 160, the pressure action pool 140 is communicated with the mounting cavity 130 through a through hole 133 (which can be in a fan shape shown in fig. 5), and further communicated with the axial drainage cavity 167 through the flow guide groove 1612 and the radial liquid outlet groove 1611 in sequence.
The rear cell electrode 165 is connected to the mounting cylinder 168 and extends into the axial drainage lumen 167.
The radial liquid outlet groove 1611 is connected with the flow guide groove 1612 through a transition surface, and the transition surface is a vertical plane, an inclined plane or an arc surface.
A first preset distance is reserved between the inner end of the radial liquid outlet groove 1611 and the inner end of the assembling cylinder 168; a second preset distance is formed between the inner end of the rear cell electrode 165 and the inner end of the assembly cylinder 168; the first preset distance is less than or equal to the second preset distance.
As shown in fig. 4, the assembly cylinder 168 includes a rear cylinder 161, an end plate 162 and an outer cylinder 163 which are integrally connected, the rear cylinder 161 is provided with a radial liquid outlet slot 1611 and an axial drainage cavity 167, and the end plate 162 radially connects the rear cylinder 161 and the outer cylinder 163.
A plurality of positioning protrusions 1632 are axially extended from the outer cylinder 163, and the fastening portion 1631 is disposed corresponding to the positioning protrusions 1632.
The application also provides a kit, which comprises a kit body 100 and the assembling seat 160, wherein the kit body 100 is provided with a forebay 120 and a mounting cavity 130 which are communicated; the mounting cylinder 168 of the mounting socket 160 is connected to the mounting chamber 130, and the front cell 120 is in communication with the axial drainage chamber 167 via the pores 172 of the microporous sheet 170.
The reagent kit and the assembly base 160 thereof provided by the embodiment can facilitate two assembly bases 160 to share one pressure action pool 140 communicated with two assembly bases 160 by arranging the radial liquid outlet groove 1611 on the assembly barrel 168 and forming a recessed area on the outer surface of the radial liquid outlet groove 1611 to form the flow guide groove 1612, so that the pressure action pool 140 can conveniently perform negative pressure drainage.
In a sixth embodiment, referring to fig. 1 to 6, an assembly base 160 is provided, in which the assembly base 160 includes an assembly cylinder 168 and a rear cell electrode 165.
The assembly cylinder 168 is a plastic assembly cylinder and is provided with an axial drainage cavity 167 and a radial liquid outlet groove 1611 which are communicated with each other, and the radial liquid outlet groove 1611 is used for discharging gas or liquid in the axial drainage cavity 167; the rear cell electrode 165 is connected to the mounting cylinder 168 and extends into the axial drainage lumen 167.
The outer surface of the assembly cylinder 168 is provided with a recessed area communicated with the radial liquid outlet groove 1611 to form a flow guide groove 1612, the flow guide groove 1612 can enable gas or liquid in the axial flow guide cavity 167 to smoothly flow to the pressure action pool 140 through the flow guide groove 1612 (for example, obliquely above) after coming out through the radial liquid outlet groove 1611 (for example, directly above), so that the two assembly bases 160 can share one pressure action pool 140 communicated with the two assembly bases 160, the pressure action pool 140 is communicated with the installation cavity 130 through a through hole 133 (which may be in a sector shape as shown in fig. 5), and further communicated with the axial flow guide cavity 167 through the flow guide groove 1612 and the radial liquid outlet groove 1611 in sequence.
The assembling barrel 168 is provided with a buckling part 1631, the buckling part 1631 is aligned with the radial liquid outlet groove 1611, the buckling part 1631 can be a buckling hole, and the buckling part 1631 and the radial liquid outlet groove 1611 are aligned to enable the die to be conveniently pulled out from the same direction during injection molding of the die.
A first preset distance is reserved between the inner end of the radial liquid outlet groove 1611 and the inner end of the assembling cylinder 168; a second preset distance is formed between the inner end of the rear cell electrode 165 and the inner end of the assembly cylinder 168; the first preset distance is less than or equal to the second preset distance. When first preset distance is less than second preset distance, the bubble in axial drainage chamber 167 discharges axial drainage chamber 167 more easily, if remain the bubble in axial drainage chamber 167, can influence and detect the precision.
The axial length of the radial exit slots 1611 in the axial drainage lumen 167 is greater than or equal to the length of the rear cell electrode 165 extending into the axial drainage lumen 167.
The inner end of the fitting cylinder 168 is provided with a microporous sheet 170 allowing cells to pass therethrough one by one. The distance from the inner end of the rear cell electrode 165 to the microporous sheet 170 is a third predetermined distance, which is 0.2-2 times the axial length of the axial drainage lumen 167. The inner end of the mounting cylinder 168 is provided with a counter-sunk platform 1613, and the microporous sheet 170 is connected with the counter-sunk platform 1613 in a matching way.
In the embodiment of the present application, the assembling cylinder 168 includes a rear cylinder 161, an end plate 162 and an outer cylinder 163 which are integrally connected, the rear cylinder 161 is provided with an axial drainage cavity 167 and a radial liquid outlet slot 1611, the end plate 162 radially connects the rear cylinder 161 and the outer cylinder 163, the outer cylinder 163 is sleeved on the periphery of the rear cylinder 161 at intervals, and the fastening part 1631 is provided on the outer cylinder 163.
The application also provides a kit, which comprises a kit body 100 and the assembling seat 160, wherein the kit body 100 is provided with a forebay 120 and a mounting cavity 130 which are communicated; the assembling cylinder 168 of the assembling seat 160 is connected with the mounting cavity 130, the front cell 120 is communicated with the axial drainage cavity 167 through the micropores 172 of the microporous sheet 170, the front cell 120, the mounting cavity 130, the axial drainage cavity 167, the radial liquid outlet groove 1611 and the pressure action cell 140 jointly form a drainage channel, and the axial drainage cavity 167 can receive negative pressure to suck a sample to be tested in the front cell 120 through the micropores 172 of the microporous sheet 170.
The reagent kit and the assembling seat 160 thereof provided by the embodiment have novel structures and are convenient to manufacture and assemble.
In a seventh embodiment, referring to fig. 1 to 6, a reagent kit is provided in the present embodiment, which includes a kit body 100, a hemolytic agent pool 106 disposed on the kit body 100, and a diluent pool 111 disposed near the hemolytic agent pool 106.
At least any two of the hemolytic agent tank 106, the diluent tank 111, and the cartridge 100 are integrally connected, and at least any two of the hemolytic agent tank 106, the diluent tank 111, and the cartridge 100 are detachably connected. That is, the cartridge 100, the hemolyzing agent tank 106, and the diluent tank 111 may be of a single-piece structure or of any separate structure.
For example, the cartridge 100, the hemolytic agent pool 106, and the diluent pool 111 are three separate pieces and detachably connected to each other; alternatively, the diluent reservoir 111 and the cartridge 100 are an integral structure, and the separate hemolytic agent container 206 is detachably assembled to the hemolytic agent reservoir 106; or, the hemolytic agent pool 106 and the box body 100 are an integral structure, and a separate diluent pool test tube is detachably assembled in the diluent pool 111; alternatively, the hemolytic agent pool 106 and the diluent pool 111 are integrally connected and detachably connected to the cartridge 100.
Any two of the hemolytic agent reservoir 106, the diluent reservoir 111, and the cartridge 100 form a combination, and a fitting portion (for example, an inner peripheral wall of a fitting hole provided in the cartridge 100) is provided on the combination, and a detachable portion (for example, an outer peripheral wall of the hemolytic agent container 206 shown in fig. 3) is provided on the other of the hemolytic agent reservoir 106, the diluent reservoir 111, and the cartridge 100, and the detachable portion is connected to the fitting portion in a fitting manner.
The surface of the assembling portion or the disassembling portion is further provided with a protrusion 2061, and the protrusion 2061 may make the hemolytic agent container 206 abut against and tightly fit with the insertion hole provided on the cartridge 100.
In one embodiment, the cartridge 100 has two assembly positions, and the hemolytic agent pool 106 and the diluent pool 111 are respectively disposed at the two assembly positions.
In the embodiment of the application, the cartridge 100 comprises a front cell 120 and a mounting cavity 130 which are communicated, the front cell 120 and the mounting cavity 130 are communicated through a via hole 132 (see fig. 5 and 6), the front cell 120 is provided with a front cell electrode 121, the kit further comprises a mounting seat 160 connected with the mounting cavity 130, the mounting seat 160 is provided with a micro-porous sheet 170 and a rear cell electrode 165, the micro-porous sheet 170 is arranged at the via hole 132, the front cell electrode 121 and the rear cell electrode 165 are respectively positioned at two sides of the micro-porous sheet 170 at intervals, the mounting seat 160 comprises a mounting cylinder 168, and the mounting cylinder 168 is provided with an axial drainage cavity 167 and a radial drainage groove 1611.
In the embodiment of the present application, the assembly cylinder 168 includes a rear cylinder 161, an end plate 162 and an outer cylinder 163 which are integrally connected, the rear cylinder 161 is provided with an axial drainage cavity 167 and a radial liquid outlet slot 1611, the end plate 162 radially connects the rear cylinder 161 and the outer cylinder 163, and the outer cylinder 163 is sleeved on the periphery of the rear cylinder 161 at intervals.
The volume of the diluent reservoir 111 is typically relatively large, and thus the volume of the diluent reservoir 111 is greater than or equal to the volume of the hemolytic agent reservoir 106 in the present embodiment.
The open ends of the diluent reservoir 111 and the hemolytic agent reservoir 106 are provided with sealing films to facilitate long-term preservation of the diluent hemolytic agent.
The kit provided by the embodiment has a novel structure and a plurality of detachable schemes, and can adapt to different detection requirements.
In an eighth embodiment, referring to fig. 1 to 6, a kit is provided in an embodiment of the present application, the kit includes a box 100 and at least one item detection cell, and the at least one item detection cell is integrally connected or detachably connected to the box 100.
The item detection pool includes a first item detection pool for performing a first item detection and a second item detection pool for performing a second item detection, and the first item detection pool and/or the second item detection pool are integrally connected or detachably connected to the cartridge 100.
The kit further comprises a third item detection cell for performing a third item detection, the third item detection cell being integrally or detachably connected to the cartridge 100.
The second project detection pool and the third project detection pool are arranged on the same side of the first project detection pool; or the second project detection pool and the third project detection pool are respectively arranged at two sides of the first project detection pool.
The detection items of the first item detection pool, the second item detection pool and the third item detection pool can be selected from specific protein detection, biochemical detection, immunoassay and blood routine detection, for example, the blood routine detection can be performed by the cooperation of the forebay 120, the installation cavity 130, the assembly seat 160 and the pressure action pool 140, and the specific protein detection, biochemical detection, immunoassay and the like can be performed by the cooperation of the optical detection cup.
The detection items of the first item detection pool, the second item detection pool and the third item detection pool are the same, different or not completely the same; or any one of the first item detection pool, the second item detection pool and the third item detection pool supports more than two detection items.
The cartridge 100 is provided with insertion holes which may comprise rectangular insertion holes 107 and circular insertion holes 108 through which the second item detection cells are inserted, or which are flanged for hanging fit with the insertion holes.
The second item detection cell includes a first cell body 207, a second cell body 208, and a connection 2071 connecting the first cell body 207 and the second cell body 208, the connection 2071 connecting the first cell body 207 and the second cell body 208 in an assembly with the case 100.
The first item detection pool and/or the second item detection pool is a light-transmitting plastic pool or a glass pool. The opening end of the first item detection cell and/or the second item detection cell is provided with a sealing film, and when the first item detection cell and/or the second item detection cell are/is used, the sealing film can be used after being punctured by a puncturing head 204 arranged on the box body 100.
The kit provided by the embodiment has a novel structure and a plurality of detachable schemes, and can adapt to different detection requirements.
In a ninth embodiment, please refer to fig. 1 to 6 together, the embodiment of the present application provides a reagent kit, which includes a kit body 100, the kit body 100 includes a front pool 120, a mounting cavity 130 and a pressure action pool, the front pool 120 is communicated with the mounting cavity 130, the pressure action pool 140 is vertically disposed, and the mounting cavity 130 is horizontally disposed.
The open end of the mounting cavity 130 faces the outer side surface of the box body 100, the kit further comprises an assembling seat 160, the assembling seat 160 is connected with the mounting cavity 130, the assembling seat 160 is provided with an axial drainage cavity 167, and the axial drainage cavity 167 is communicated with the pressure action pool 140.
Mounting cavity 130 forms a drainage gap with mounting cup 160, through which axial drainage cavity 167 communicates with pressure application reservoir 140.
The assembling seat 160 is provided with a radial liquid outlet groove 1611, and the axial drainage cavity 167 is communicated with the pressure action pool 140 through the radial liquid outlet groove 1611; mounting cup 160 is provided with a channel 1612 adjacent radial channel 1611, and axial channel 167 is in communication with pressure application cell 140 via radial channel 1611 and channel 1612.
The mounting seat 160 is provided with a microporous sheet 170 and a rear cell electrode 165, the front cell 120 is provided with a front cell electrode 121, and the front cell electrode 121 and the rear cell electrode 165 are respectively positioned at both sides of the microporous sheet 170 at intervals.
The mounting socket 160 is snap fit, threaded, interference fit, laser welded, or adhesively fit with the mounting cavity 130.
The kit further includes an inner seal ring 164 and an outer seal ring 166, the inner seal ring 164 being disposed between the microporous sheet 170 and the cartridge body 100, and the outer seal ring 166 being disposed between the mounting cup 160 and the cartridge body 100.
In the embodiment of the present application, the forebay 120 and the installation cavity 130 are both two sets, and one pressure action pond 140 is communicated with the two sets of installation cavities 130.
The reagent box provided by the embodiment has a novel structure, the front pool 120, the installation cavity 130 and the pressure action pool 140 are communicated with each other and are sequentially and vertically arranged, the open end of the pressure action pool 140 is positioned on the upper surface of the box body 100, and the negative pressure source can be applied from the upper part of the box body 100, so that the structure of the box body 100 can be simplified, and the side surface of the box body 100 is prevented from having a more convex structure.
In a tenth embodiment, referring to fig. 1 to 6, a reagent kit is provided, which includes a plurality of first pool positions, and centers of the plurality of first pool positions are substantially arranged in a first straight line or a first arc line.
The kit also comprises a plurality of second pool positions with the centers approximately arranged in a second straight line, and the first straight line and the second straight line are arranged in parallel or at vertical intervals.
Or, the kit is a plurality of second pond positions that the second pitch arc was arranged including the center, and first pitch arc and second pitch arc are parallel interval and set up, and the pitch arc can be the pitch arc that corresponds of 0 ~ 360 central angle.
The plurality of first cell sites and/or the plurality of second cell sites comprise impedance detection cells and/or optical detection cells.
The plurality of first tank positions and/or the plurality of second tank positions further comprise a diluent tank 111, and the diluent tank 111 is used for packaging diluent; the plurality of first well sites and/or the plurality of second well sites further comprise a hemolytic agent well 106, wherein the hemolytic agent well 106 is used for encapsulating hemolytic agent; the one or more first well locations and/or the plurality of second well locations further comprise a sample dilution well 112, the sample dilution well 112 being for sample dilution.
The impedance detection cell is provided with a light transmission detection window used for matching optical detection, namely, one of the front cells 120 is provided with a light transmission detection window used for matching optical detection, the front cell 120 can be integrally made of transparent plastic, and the transmittance and the smoothness of the light transmission detection window can be the same as those of the front cell 120 or higher than other parts of the front cell 120.
The plurality of first pond positions and/or the plurality of second pond positions also comprise a plurality of plug-in mounting holes.
The plurality of first wells and/or the plurality of second wells comprise at least one pipette head receiving well (101, 102, 103) and/or a sample receiving well 105.
The first plurality of cuvettes and/or the second plurality of cuvettes include at least one puncture tip receiving cuvette 104. The application provides a kit is degradable plastic kit, through arranging a plurality of pond position straight lines, can conveniently move the liquid device and carry out the motion of short route when automated inspection, wherein, move the liquid device and be arranged in shifting and mixing the liquid in each cell body.
In an eleventh embodiment, referring to fig. 1 to 6 together, the present application provides a reagent kit, which includes a kit body 100, and the kit body 100 is provided with a detection area (e.g., an area formed by a front pool 120, a mounting cavity 130, a pressure action pool 140, and a mounting seat 160), a reagent area (e.g., an area formed by a diluent pool 111, a hemolytic agent pool 106, and a sample accommodating pool 105), and an accessory placement area (e.g., an area formed by pipette tip accommodating pools 101, 102, and 103, and a puncture tip accommodating pool 104).
The cartridge 100 further comprises an expandable region (e.g., the region formed by the rectangular insertion hole 107 and the circular insertion hole 108 in the figure) disposed near the detection region, the expandable region being located at one side of the detection region, or the expandable region being located at one side of the reagent region.
The accessory placing area is arranged close to the reagent area, and the detection area is arranged close to the reagent area.
The detection zone comprises an impedance detection cell and/or an optical detection cell comprising a sensor for detecting any one of HGB, CRP, SAA parameters.
The reagent zone includes at least one of a diluent reservoir, a hemolytic agent reservoir, and a sample receiving reservoir 105.
The reagent zone includes a cell body region for removably mounting at least one of a diluent container, a hemolytic agent container 206, and a sample receiving cell 105.
The accessory placement area includes placement locations for pipette heads 201, 202, 203 and/or piercing head 204.
The expandable zone includes a removable optical detection cell and/or an impedance detection cell, the optical detection cell including a sensor for detecting any one of HGB, CRP, SAA parameters.
The application provides a kit is degradable plastic kit, sets up through the subregion and can make things convenient for the motion that moves liquid device and carry out shorter route when automated inspection.
In a twelfth embodiment, referring to fig. 1 to 6 together, the reagent cartridge provided in the embodiments of the present application includes a cartridge body 100, wherein the cartridge body 100 is provided with a detection area (e.g., an area formed by a front pool 120, a mounting cavity 130, a pressure action pool 140, and a mounting seat 160), a reagent area (e.g., an area formed by a diluent pool 111, a hemolytic agent pool 106, and a sample accommodating pool 105), and an accessory placement area (e.g., an area formed by pipette tip accommodating pools 101, 102, and 103, and a puncture tip accommodating pool 104), and the reagent area is disposed near the accessory placement area.
The cartridge 100 also includes an expandable region (e.g., the region defined by rectangular openings 107 and circular openings 108) that is positioned adjacent to the detection zone. Alternatively, the expandable region is disposed adjacent to a side of the detection region or adjacent to a side of the reagent region.
The reagent area comprises a plurality of reagent tanks which are approximately arranged in a straight line or an arc line.
The detection zone comprises an impedance detection cell and/or an optical detection cell comprising a sensor for detecting any one of HGB, CRP, SAA parameters.
The accessory placement area includes placement locations for pipette heads 201, 202, 203 and/or piercing head 204.
The expandable zone includes a removable optical detection cell and/or an impedance detection cell, the optical detection cell including a sensor for detecting any one of HGB, CRP, SAA parameters.
The reagent zone comprises at least two tank body zones, and the at least two tank body zones comprise bottom tanks and/or bottomless insertion holes.
The accessory area includes one or more bottomed wells for housing pipette heads 201, 202, 203 and/or piercing head 204.
The expandable area is provided with a circular insertion hole 108 and a rectangular insertion hole 107, the circular insertion hole 108 and the rectangular insertion hole 107 are used for installing a detection cell, and the detection cell is an optical detection cell and/or an impedance detection cell. The application provides a kit is degradable plastic kit, sets up through the subregion and can make things convenient for the motion that moves liquid device and carry out shorter route when automated inspection.
In a thirteenth embodiment, referring to fig. 1 to 6, a reagent kit according to an embodiment of the present disclosure includes a kit body 100, the reagent kit is used for detecting a sample, and the kit body 100 is provided with a supporting portion so that the reagent kit can be stably supported on a supporting surface.
In one embodiment, the box 100 includes two supporting vertical plates (not shown) as supporting parts. The support vertical plate can be provided with a mark which is a bar code, a two-dimensional code or an identification chip to record the relevant parameters of the kit.
The case 100 is provided with at least one support platform or support surface near the center of gravity of the reagent cartridge, and the support platform or support surface serves as a support portion.
In one embodiment, the case 100 is provided with three supporting protrusions, the three supporting protrusions form a triangle, and the projection of the gravity center of the reagent kit falls within the area formed by the triangle.
In one embodiment, the cartridge 100 includes at least one cell body, the bottom of which may serve as a support portion.
Optionally, the supporting vertical plate or the supporting platform or the supporting surface or the supporting protrusion and the bottom of the pool body are used together as a supporting part.
The cell body includes a containing cavity and a skirt 124 extending downward from the containing cavity (refer to fig. 6, the skirt 124 is used as a support part under the bottom 123 of the cell 120), and the containing cavity can contain reagents, samples or places accessories (201 and 204).
The present application provides a cartridge 100 that is a degradable plastic cartridge. The kit is provided with an impedance detection pool and/or an optical detection pool.
The reagent box that this embodiment provided is equipped with more cell body to probably cross the bottom of cell body and/or the supporting part formation stable support of additional setting, avoid the reagent box to empty easily.
A fourteenth embodiment, please refer to fig. 1 to 6 together, the embodiment of the present application provides a kit, the kit includes a box body 100, the box body 100 includes a plurality of cell bodies, each cell body includes a receiving cavity and a supporting portion connected to the receiving cavity, the supporting portion is a solid structure or a hollow structure, the solid or hollow supporting portion can increase the relative height of the bottom of the receiving cavity, so as to facilitate the reagent absorption, the corresponding liquid-transferring device can not be inserted too deep, and further save the pre-stored amount of the reagent, if the solid structure is adopted, the center of gravity of the box body 100 can be moved down, so that the whole is more stable; when the hollow structure is hollow, plastic materials of the box body 100 can be saved.
The height of the supporting part is greater than or equal to the wall thickness of the accommodating cavity, the bottom of the accommodating cavity can be a conical bottom, specifically can be a conical arc bottom, a triangular pyramid or a polygonal pyramid bottom, and the conical bottom extends into a hollow area at the bottom of the supporting part; or the bottom of the accommodating cavity is a plane bottom, and the accommodating cavity is connected with the supporting part through the plane bottom.
When the supporting part is of a hollow structure, the bottom of the supporting part is provided with an opening end or a closed end.
The accommodating cavity and the supporting part are integrally formed or detachably connected.
When the supporting part is a hollow structure, the cross section of the hollow structure is square, circular, polygonal or special-shaped, and the height of the supporting part is 0.1-0.8 times of the height of the pool body.
The cell body may be any cell body such as a reagent cell, a detection cell, a sample dilution cell 112, or an accessory placement cell (101-.
The detection cell is used for impedance detection or optical detection.
The embodiment of the present application further provides a sample detection apparatus, which includes the aforementioned reagent kit and a detection seat matched with the reagent kit, wherein the detection seat is used for sample analysis and detection, the detection seat is provided with a power supply assembly electrically connected to the front cell electrode 121 and the rear cell electrode 165, and the detection seat can be further provided with optical detection assemblies located on two opposite sides of the optical detection cell (for example, the first cell body 207).
The reagent box that this embodiment provided can make things convenient for the liquid-transfering device to move the liquid through setting up the bottom of the pool of co-altitude not, and the liquid-transfering device can not insert too deeply, and then can practice thrift the volume of prestoring of reagent.
In a fifteenth embodiment, please refer to fig. 1 to fig. 6, an embodiment of the present application provides a kit, which includes a box 100, wherein the box 100 is provided with an accessory placing area (101-.
The lower side of the accessory placing area is provided with a liquid leakage prevention structure which can be a bottom tank. The liquid leakage preventing structure is integrally formed with or detachably connected to the case 100. The accessory placing area is provided with a placing hole, and the accessories (201 and 204) are placed in the placing hole.
The aperture of the placing hole is smaller than or equal to the maximum radial dimension of the accessory (201 and 204), so that the accessory (201 and 204) is prevented from completely sinking into the placing hole, and the bottom of the accessory (201 and 204) is prevented from contacting and deforming with the bottom of the pool body when the accessory (201 and 204) is inserted.
The box body 100 is provided with a containing cavity corresponding to the placing hole, and the accessories (201 and 204) are contained in the containing cavity. The bottom of the accommodating cavity is provided with a sealing structure.
The receiving cavity is integrally formed with the box 100 or detachably connected thereto.
The depth of the inner cavity of the accommodating cavity is greater than or equal to the length of the accessory (201 and 204) extending into the accommodating cavity, so that the accessory (201 and 204) is prevented from being too protruded out of the surface of the box body 100 when being placed in the accommodating cavity, and meanwhile, the contact deformation of the bottom of the accessory (201 and 204) and the bottom of the pool body when the accessory (201 and 204) is inserted can be avoided.
The length of the accessory (201 and 204) extending into the accommodating cavity is 0.4-1 times of the length of the accessory.
The embodiment of the application also provides a sample detection device, which comprises the kit and a detection seat matched with the kit, wherein the detection seat is used for sample analysis and detection.
When the kit provided by the embodiment is used for removing accessories, residual liquid carried on the surfaces of the accessories can be prevented from leaking by receiving the accessories through the pool with the bottom.
In a sixteenth embodiment, referring to fig. 1 to 6, an embodiment of the present disclosure provides a detection cup assembly, which includes a first tank 207 and a second tank 208 connected to the first tank 207.
The first tank body 207 and the second tank body 208 are connected by a connecting piece 2071, and the connecting piece 2071 is integrally formed with or detachably connected with at least one of the first tank body 207 and the second tank body 208.
The connecting member 2071 is provided with at least one cup holder 2072, and the cup holder 2072 is detachably connected with the first tank body 207 or the second tank body 208.
In an embodiment, the connecting member 2071 is provided with a cup holder 2072 and the connecting member is integrally connected to the first tank 207, and the cup holder 2072 is provided with a placement hole having a shape the same as or different from the cross-sectional shape of the first tank 207.
In an embodiment, the connecting member 2071 is provided with two cup holders 2072, and the two cup holders 2072 are respectively provided with a first placing hole and a second placing hole, and the first placing hole and the second placing hole have the same or different shapes.
The first cell body 207 is a detection cup, the second cell body 208 is a reagent cup, and during detection, a reagent in the second cell body 208 is added into the first cell body 207 to prepare a sample to be detected, and then detection is performed.
The first cell body 207 is provided with an optical detection window for optical detection, such as optical detection by transmitted light or optical detection by scattered light.
The cross-sectional shapes of the first tank body 207 and the second tank body 208 are the same or different; or the heights of the first tank body 207 and the second tank body 208 are the same or different, and a fool-proof effect can be achieved through differential arrangement, so that the assembly and the identification are convenient.
The embodiment of the application also provides a kit, which comprises a box body 100 and the detection cup assembly, wherein the box body 100 is provided with an installation part, the detection cup assembly is provided with a matching part, and the installation part is connected with the matching part.
The matching part can be a convex part or a concave part arranged on the side surface of the detection cup component, and the convex part or the concave part is matched and connected with the mounting part; or the matching part is a positioning flange arranged on the detection cup assembly, and the positioning flange is matched and connected with the mounting part, for example, the flange structure is hung on the insertion hole on the box body 100.
The detection cup subassembly that this embodiment provided novel structure, specific detection project can set corresponding demand reagent on saucer 2072, improvement detection efficiency that can be very big, and detection project can the nimble selection.
In a seventeenth embodiment, referring to fig. 1 to 6, a kit is provided, which includes a case 100 and a mounting seat 160.
In the embodiment of the application, the axis of the front cell electrode 121 and the axis of the rear cell electrode 165 are substantially the same straight line, and experiments prove that the detection precision is relatively high when the axis of the front cell electrode 121 and the axis of the rear cell electrode 165 are coaxial, the front cell electrode 121 and the rear cell electrode 165 are both cylindrical electrodes, and the manufacturing process and the assembly process are both simple and convenient.
The assembly seat 160 is provided with an axial drainage cavity 167, the axial drainage cavity 167 is communicated with the front cell 120 through the microporous sheet 170, and the front cell electrode 121 and the rear cell electrode 165 are positioned at two sides of the microporous sheet 170.
The microporous sheet 170 includes a sheet body 171, the sheet body 171 is provided with micropores 172 allowing cells to pass through one by one, the microporous sheet 170 is mounted on the mounting seat 160 or the cartridge 100, or the microporous sheet 170 and the mounting seat 160 or the cartridge 100 are integrally formed.
The axis of the front cell electrode 121, the axis of the rear cell electrode 165, and the axis of the microporous sheet 170 are substantially collinear.
The front cell electrode 121 protrudes, is flush with or is recessed in the inner wall of the front cell 120; the rear cell electrode 165 projects, is flush with, or is recessed into the bottom wall of the axial drainage lumen 167. The two ends of the front cell electrode 121 and the rear cell electrode 165 are not particularly limited, the front cell electrode 121 and the rear cell electrode 165 are in contact with a liquid to be detected during detection, and the outer ends of the front cell electrode 121 and the rear cell electrode 165 are used for externally connecting to an electric power supply component.
The cartridge 100 is provided with a mounting cavity 130, the mounting seat 160 includes a mounting cylinder 168, and the mounting cavity 130 is coaxially connected with the mounting cylinder 168.
The mounting sleeve 168 is snap fit, threaded, interference fit, laser welded, or adhesively engaged with the mounting cavity 130.
The front cell electrode 121 is disposed on the case 100 and protrudes, is flush with or is recessed on the outer side of the case 100, and the rear cell electrode 165 is disposed on the mounting seat 160 and protrudes, is flush with or is recessed on the outer side of the mounting seat 160.
The embodiment of the application also provides a sample detection device, which comprises the kit and a detection seat matched with the kit, wherein the detection seat is used for sample analysis and detection.
In an eighteenth embodiment, referring to fig. 1 to 6, a reagent kit is provided in the present application, which includes a box body 100 and a holding portion 150, wherein the holding portion 150 is disposed on the box body 100.
The grip 150 may be disposed near the center of the side of the case 100 or near the center of the upper surface of the case 100.
The number of the holding portions 150 is two, and the two holding portions 150 are respectively disposed at two opposite sides of the box body 100.
The grip part 150 protrudes from the upper surface or the side surface of the case 100. The outer surface of the grip part 150 is provided with a catching protrusion 151 or a catching recess.
The grip portion 150 is provided with a slip-preventing portion 152 at the tip or outside thereof.
The holding portion 150 is an elastic member, a recess 154 is disposed on a side surface of the box 100, and the holding portion 150 is connected to the recess 154 in a matching manner.
The grip portion 150 is integrally or detachably connected to the recessed portion 154.
The holding part 150 is slidably connected with the recess 154, so that the holding part 150 and the box 100 move relatively, the holding part 150 can extend and retract relative to the box 100, and the storage box is convenient, does not occupy space and can be drawn out when needed.
The embodiment of the present application further provides a sample detection device, which includes the aforementioned reagent kit and a detection seat matched with the reagent kit, wherein the holding portion 150 is connected with the detection seat in a matching manner.
In a nineteenth embodiment, referring to fig. 1 to 6, a reagent kit is provided according to an embodiment of the present application, which includes a kit body 100 and a blocking portion 153.
The cartridge 100 includes at least one well site (e.g., sample receiving well 105); the well is used to hold a test tube (e.g., sample tube 205).
The blocking portion 153 is provided at one side of the well site for hooking a test tube cap (not shown) of the test tube to prevent the opened test tube cap from being restored to cover the open end of the test tube.
In an embodiment, the dam 153 may be disposed to protrude, be flush with, or be recessed in the upper surface or the side surface of the case 100.
In one embodiment, the blocking portion 153 includes a connecting member connected to the case 100 and a stopping portion bent and extended from the connecting member. The end of the blocking portion is provided with a back hook portion extending toward the case 100.
In another embodiment, the side surface of the case 100 is protruded outward to form a dam 153; or the blocking part 153 is a groove formed on the upper surface of the case 100; or the upper surface of the box body 100 is provided with a recess, the inner wall of the recess forms a blocking part 153, a test tube cap of a test tube can be inserted into the recess after being opened, and the size of the recess can correspond to that of the test tube cap to realize relatively tight fit.
The blocking portion 153 is integrally formed with or detachably connected to the case 100. Specifically, the dam 153 is snap-fit, plug-in, threaded, or removably connected to the cartridge 100 via screws/pins.
In other embodiments, the dam 153 is also slidably coupled to the cartridge 100.
In the embodiment, the well (e.g., sample receiving well 105) is disposed near the edge of the cassette 100, and the blocking portion 153 is disposed at the edge of the cassette 100.
The embodiment of the application also provides a sample detection device, which comprises the kit and a detection seat matched with the kit, wherein the detection seat is used for sample analysis.
The above embodiments are merely examples and are not intended to limit the scope of the present disclosure, and all modifications, equivalents, and flow charts using the contents of the specification and drawings of the present disclosure, which are directly or indirectly applied to other related technical fields, are included in the scope of the present disclosure.
Claims (10)
1. A fitting seat, characterized in that it comprises:
the assembling cylinder is provided with an axial drainage cavity and a radial liquid outlet groove which are communicated with each other, and the radial liquid outlet groove is used for discharging gas or liquid in the axial drainage cavity;
and the rear pool electrode is connected with the assembly cylinder and extends to the axial drainage cavity.
2. The fitting seat according to claim 1, wherein:
a first preset distance is reserved between the inner end of the radial liquid outlet groove and the inner end of the assembling cylinder;
a second preset distance is reserved between the inner end of the rear cell electrode and the inner end of the assembly cylinder;
the first preset distance is less than or equal to the second preset distance.
3. The fitting seat according to claim 1, wherein: the axial length of the radial liquid outlet groove in the axial drainage cavity is larger than or equal to the length of the rear pool electrode extending into the axial drainage cavity.
4. The fitting seat according to claim 1, wherein: the outer surface of the assembling cylinder is provided with a sunken area communicated with the radial liquid outlet groove to form a flow guide groove.
5. The fitting seat according to claim 1, wherein: the inner end of the assembly cylinder is provided with a microporous sheet which allows cells to pass through one by one.
6. The fitting seat according to claim 5, wherein: the distance from the inner end of the rear cell electrode to the microporous sheet is a third preset distance, and the third preset distance is 0.2-2 times of the axial length of the axial drainage cavity.
7. The fitting seat according to claim 5, wherein: the inner end of the assembling cylinder is provided with a sinking platform, and the microporous sheet is connected with the sinking platform in a matching way.
8. The fitting seat according to claim 1, wherein: the assembly section of thick bamboo is including a back pond section of thick bamboo, end plate and urceolus of body coupling, a back pond section of thick bamboo is equipped with axial drainage chamber with radially go out the liquid groove, the end plate will a back pond section of thick bamboo with urceolus radial connection, urceolus spacer sleeve is located the periphery of a back pond section of thick bamboo.
9. The fitting seat according to claim 1, wherein: the radial liquid outlet groove is in a circular hole shape, a kidney-shaped hole shape or a rectangular hole shape.
10. A kit, characterized in that: the kit comprises:
the box body is provided with a forebay and an installation cavity which are communicated;
the mounting cup of any of claims 1-9, said mounting cartridge being connected to said mounting chamber, said forebay being in communication with said axial drainage chamber.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202120322820.8U CN216350758U (en) | 2021-02-03 | 2021-02-03 | Kit and assembly seat |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN202120322820.8U CN216350758U (en) | 2021-02-03 | 2021-02-03 | Kit and assembly seat |
Publications (1)
Publication Number | Publication Date |
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CN216350758U true CN216350758U (en) | 2022-04-19 |
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Family Applications (1)
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CN202120322820.8U Active CN216350758U (en) | 2021-02-03 | 2021-02-03 | Kit and assembly seat |
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2021
- 2021-02-03 CN CN202120322820.8U patent/CN216350758U/en active Active
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