CN211886775U

CN211886775U - Reaction pressure monitoring device for pharmaceutical product raw material research and development

Info

Publication number: CN211886775U
Application number: CN202020463217.7U
Authority: CN
Inventors: 于晓英
Original assignee: Qingdao Yingqi Biotechnology Co ltd
Current assignee: Qingdao Yingqi Biotechnology Co ltd
Priority date: 2020-04-02
Filing date: 2020-04-02
Publication date: 2020-11-10
Anticipated expiration: 2030-04-02

Abstract

The utility model discloses a medicine product raw materials research and development is with reaction pressure monitoring device relates to medicine product raw materials research and development technical field, including reaction pressure adjustment mechanism and pressure settlement monitoring mechanism, reaction pressure adjustment mechanism includes that end cover, reaction gas lead to mouth, the reation kettle body, support, adjusting floor, gusset, flexible post, fixed column, screw rod groove, screw rod, spout, slider, motor groove, motor, reduction gear, screw thread slider. The utility model relates to a scheme has avoided baroceptor direct application in reaction environment through the design of pressure setting monitoring mechanism and reaction pressure adjustment mechanism, has realized reaction pressure's accurate monitoring and regulation control, has solved the monitoring of medicine product raw materials research and development in-process reaction pressure and the great and problem that the precision can not be guaranteed of control regulation degree of difficulty.

Description

Reaction pressure monitoring device for pharmaceutical product raw material research and development

Technical Field

The utility model belongs to the technical field of medicine product raw materials research and development technique and specifically relates to a medicine product raw materials is developed and is used reaction pressure monitoring device.

Background

A plurality of chemical reactions are involved in the research and development process of raw materials of medical products, in the process that some gases participate in the reaction, the reaction pressure is a key factor influencing the reaction efficiency, and because the air pressure sensor is not suitable for being used in corrosive environments, the monitoring, control and adjustment difficulty of the reaction pressure in the research and development process of the raw materials of the medical products is high, and the precision cannot be guaranteed.

SUMMERY OF THE UTILITY MODEL

In order to overcome the above-mentioned defect that exists among the prior art, the utility model provides a reaction pressure monitoring device is used in the research and development of pharmaceutical product raw materials.

The utility model provides a technical scheme that its technical problem adopted is: a reaction pressure monitoring device for research and development of pharmaceutical product raw materials comprises a reaction pressure adjusting mechanism and a pressure setting and monitoring mechanism, wherein the reaction pressure adjusting mechanism comprises an end cover, a reaction gas inlet, a reaction kettle body, a support, an adjusting bottom plate, a rib plate, a telescopic column, a fixing column, a screw groove, a screw rod, a sliding groove, a sliding block, a motor groove, a motor, a speed reducer and a threaded sliding block, the pressure setting and monitoring mechanism comprises a U-shaped pipe, an electric control valve, a latex sleeve, water, a connecting block, a stay wire displacement sensor, a gas pipe, a gas pressure sensor, a cylinder, a piston, a fine adjustment column, a guide frame, a fine adjustment screw groove, a fine adjustment threaded sliding block, a fine adjustment speed reducer and a fine adjustment motor, the end cover is tightly pressed and sealed on the upper end of the reaction kettle body through bolts, the reaction gas inlet is arranged at the central position of the upper end, the adjusting bottom plate is arranged on the inner wall of the reaction kettle body in a sealing fit manner through a sealing washer, the head end of the telescopic column is rigidly arranged at the central position of the lower end face of the adjusting bottom plate through a rib plate, the telescopic column is arranged inside a fixed column in a fit manner, a screw groove is arranged in the hollow part of the inside of the telescopic column, a screw is arranged inside the screw groove, the screw is rigidly arranged at the power output end of the speed reducer, the sliding grooves are symmetrically arranged in the hollow part of the inside of the fixed column in groups of 2, the sliding blocks are arranged in the sliding grooves in a fit manner, the sliding blocks are arranged on the outer wall of the bottom of the telescopic column in a rigid and integrated manner in groups of 2, the motor groove is arranged in the hollow part of the inside of the fixed column, the motor is, the threaded slide block is installed on the screw in a matched mode, the head end of the U-shaped pipe is installed on the right side wall of the reaction kettle body in a rigid integrated mode, the electric control valve is installed at the position, close to the head end, of the U-shaped pipe, the latex sleeve is filled with water and installed in the U-shaped pipe, the connecting block is installed at the right end of the latex sleeve, the stay wire displacement sensor is installed in the installing groove formed in the U-shaped pipe in a rigid mode, the stay wire displacement sensor is connected with the connecting block through the stay wire port, the air cylinder is installed at the tail end of the U-shaped pipe in a rigid integrated mode, the air delivery pipe is installed on the side wall of the bottom of the air cylinder in a rigid mode, the air pressure sensor is installed on the bottom face of the inner wall of the air cylinder, the piston is, the fine setting screw rod is installed in fine setting screw rod inslot portion, fine setting screw rod rigid mount is in fine setting reduction gear power take off end, fine setting thread slider cooperation is installed in the fine setting screw rod, fine setting thread slider rigid mount is in fine setting screw rod inslot end inner wall, fine setting slider divide 2 rigid symmetry of group to install in fine setting post terminal outer wall, the fine setting reduction gear is fixed in fine setting motor casing through the reduction gear support, the fine setting motor passes through motor support rigid mount in cylinder upper end outer wall, fine setting reduction gear power take off end rigid connection is in fine setting motor power take off shaft.

According to the reaction pressure monitoring device for the research and development of the raw materials of the medical products, the side wall of the rear end of the reaction kettle body is provided with the material taking sealing door.

According to the reaction pressure monitoring device for the research and development of the raw materials of the medical products, the gas transmission pipe is provided with the electric control valve and is connected with the air pump.

According to the reaction pressure monitoring device for the research and development of the raw materials of the medical products, the lubricating oil is smeared on the inner wall of the U-shaped pipe so as to ensure that the latex sleeve filled with water can smoothly move along with the pressure change.

The beneficial effects of the utility model are that, the utility model provides a design of scheme through pressure setting monitoring mechanism and reaction pressure adjustment mechanism has avoided baroceptor direct application in reaction environment, has realized reaction pressure's accurate monitoring and regulation control, has solved the monitoring of medicine product raw materials research and development in-process reaction pressure and the great and problem that the precision can not be guaranteed of the control regulation degree of difficulty.

Drawings

The present invention will be further explained with reference to the drawings and examples.

Fig. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic view of the overall internal structure of the present invention;

FIG. 3 is a schematic view of the internal mounting structure of the fixing column of the present invention;

fig. 4 is the utility model discloses a whole internal structure schematic diagram of pressure setting monitoring mechanism.

In the figure, 1, an end cover, 2, a reaction gas inlet, 3, a reaction kettle body, 4, a support, 5, an adjusting bottom plate, 6, a rib plate, 7, a telescopic column, 8, a fixed column, 9, a screw rod groove, 10, a screw rod, 11, a sliding groove, 12, a sliding block, 13, a motor groove, 14, a motor, 15, a reducer, 16, a threaded sliding block, 17, a U-shaped pipe, 18, an electric control valve, 19, a latex sleeve, 20, water, 21, a connecting block, 22, a stay wire displacement sensor, 23, a gas pipe, 24, a gas pressure sensor, 25, a cylinder, 26, a piston, 27, a fine adjustment column, 28, a guide frame, 29, a fine adjustment screw rod groove, 30, a fine adjustment screw rod, 31, a fine adjustment threaded sliding block, 32, a fine adjustment sliding block, 33, a fine adjustment.

Detailed Description

In order to more clearly illustrate the technical solution of the present invention, the following provides a further description of the present invention with reference to the accompanying drawings, and obviously, the following described drawings are only one embodiment of the present invention, and for those skilled in the art, other embodiments can be obtained according to the drawings and the embodiment without any creative work, and all belong to the protection scope of the present invention.

A reaction pressure monitoring device for research and development of pharmaceutical product raw materials comprises a reaction pressure adjusting mechanism and a pressure setting and monitoring mechanism, wherein the reaction pressure adjusting mechanism comprises an end cover 1, a reaction gas inlet 2, a reaction kettle body 3, a support 4, an adjusting bottom plate 5, a rib plate 6, a telescopic column 7, a fixed column 8, a screw rod groove 9, a screw rod 10, a sliding groove 11, a sliding block 12, a motor groove 13, a motor 14, a speed reducer 15 and a threaded sliding block 16, the pressure setting and monitoring mechanism comprises a U-shaped pipe 17, an electric control valve 18, a latex sleeve 19, water 20, a connecting block 21, a stay wire displacement sensor 22, a gas pipe 23, a gas pressure sensor 24, a cylinder 25, a piston 26, a fine adjustment column 27, a guide frame 28, a fine adjustment screw rod groove 29, a fine adjustment screw rod 30, a fine adjustment threaded sliding block 31, a fine adjustment sliding block 32, a fine adjustment speed reducer 33 and a fine adjustment motor 34, the reaction gas inlet 2 is arranged at the central position of the upper end face of the end cover 1, the brackets 4 are uniformly arranged on the outer wall of the reaction kettle body 3 in a 360-degree annular array in groups of 4, the adjusting bottom plate 5 is arranged on the inner wall of the reaction kettle body 3 in a sealing fit manner through a sealing washer, the head end of the telescopic column 7 is rigidly arranged at the central position of the lower end face of the adjusting bottom plate 5 through a rib plate 6, the telescopic column 7 is arranged in the fixed column 8 in a fit manner, the screw groove 9 is arranged in the hollow part of the inner part of the telescopic column 7, the screw 10 is arranged in the screw groove 9, the screw 10 is rigidly arranged at the power output end of the speed reducer 15, the slide grooves 11 are symmetrically arranged in the hollow part of the inner part of the fixed column 8 in groups of 2, the slide blocks 12 are arranged in the slide grooves 11, the electric motor 14 is rigidly mounted on the bottom surface of the motor groove 13, the speed reducer 15 is fixedly mounted on a shell of the electric motor 14 through a speed reducer support, a power input end of the speed reducer 15 is rigidly connected to a power output shaft of the electric motor 14, the thread slider 16 is rigidly mounted on the inner wall of the bottom of the screw groove 9, the thread slider 16 is mounted on the screw 10 in a matching manner, a head end of the U-shaped tube 17 is rigidly and integrally mounted on the right side wall of the reaction kettle body 3, the electric control valve 18 is mounted on the position, close to the head end, of the U-shaped tube 17, the latex sleeve 19 is filled with water 20 and mounted in the U-shaped tube 17, the connecting block 21 is mounted at the right end of the latex sleeve 19, the stay wire displacement sensor 22 is rigidly mounted in a mounting groove arranged in the U-shaped tube 17, the stay, the air pressure sensor 24 is arranged on the bottom surface of the inner wall of the air cylinder 25, the piston 26 is arranged on the inner wall of the air cylinder 25 in a sealing and matching way through a sealing washer, the head end of the fine adjustment column 27 is rigidly arranged at the central position of the upper end surface of the piston 26, the guide frame 28 is symmetrically and symmetrically arranged on the inner wall of the upper end of the air cylinder 25 in 2 groups, the fine adjustment screw groove 29 is arranged in the hollow part of the fine adjustment column 27, the fine adjustment screw 30 is arranged in the fine adjustment screw groove 29, the fine adjustment screw 30 is rigidly arranged at the power output end of the fine adjustment reducer 33, the fine adjustment screw slider 31 is arranged on the fine adjustment screw 30 in a matching way, the fine adjustment screw 31 is rigidly arranged on the inner wall of the tail end of the fine adjustment screw groove 29, the fine adjustment slider 32 is symmetrically and rigidly arranged on the outer wall of, the power input end of the fine adjustment speed reducer 33 is rigidly connected with the power output shaft of the fine adjustment motor 34.

In detail, the lateral wall of the rear end of the reaction kettle body 3 is provided with a material taking sealing door, an electric control valve is installed on the gas pipe 23, the gas pipe 23 is connected with an air pump, lubricating oil is smeared on the inner wall of the U-shaped pipe 17 to ensure that the latex sleeve 19 filled with water 20 inside moves smoothly along with the pressure change, and the reaction pressure monitoring device for the research and development of the raw materials of the medicine products has the following action principle: in the closed state of the electric control valve 18, air is input into the air cylinder 25 through the air pipe 23, the air pressure value in the air cylinder 25 is monitored through the air pressure sensor 24, the air input is stopped until the air pressure value in the air cylinder 25 approaches to the set air pressure, the moving direction of the piston 26 is determined according to the air pressure value monitored by the air pressure sensor 24, the micro-adjustment of the air pressure value is carried out through the movement of the piston 26, the reaction gas rushing into the reaction kettle body 3 is quantitatively determined according to the set value after the air pressure value is stabilized at the set value, the electric control valve 18 is opened at the moment, the latex sleeve 19 filled with water 20 in the U-shaped pipe 17 is in a balanced state, the reaction gas is reduced along with the reaction after the reaction starts, the pressure value in the reaction kettle body 3 is reduced, the connecting block 21 monitors a signal through the stay wire displacement sensor 22 along with the movement of the latex sleeve 19 and transmits the signal to the reaction pressure adjusting mechanism to carry The introduction of the reaction gas and the adjustment process are continued until the reaction is completed.

The above embodiments are only exemplary embodiments of the present invention, and are not intended to limit the present invention, and the protection scope of the present invention is defined by the claims. Various modifications and equivalents of the invention can be made by those skilled in the art within the spirit and scope of the invention, and such modifications and equivalents should also be considered as falling within the scope of the invention.

Claims

1. The utility model provides a medicine product raw materials research and development is with reaction pressure monitoring device, includes reaction pressure adjustment mechanism and pressure setting monitoring mechanism, its characterized in that: the reaction pressure adjusting mechanism comprises an end cover (1), a reaction gas inlet (2), a reaction kettle body (3), a support (4), an adjusting bottom plate (5), rib plates (6), a telescopic column (7), a fixing column (8), a screw groove (9), a screw (10), a sliding groove (11), a sliding block (12), a motor groove (13), a motor (14), a speed reducer (15) and a threaded sliding block (16), and the pressure setting and monitoring mechanism comprises a U-shaped pipe (17), an electric control valve (18), a latex sleeve (19), water (20), a connecting block (21), a stay wire displacement sensor (22), a gas pipe (23), a gas pressure sensor (24), a cylinder (25), a piston (26), a fine adjustment column (27), a guide frame (28), a fine adjustment screw groove (29), a fine adjustment screw (30), a fine adjustment threaded sliding block (31), a fine adjustment sliding block (32), The reaction kettle comprises a fine-tuning speed reducer (33) and a fine-tuning motor (34), wherein an end cover (1) is tightly pressed and sealed to be installed at the upper end of a reaction kettle body (3) through bolts, a reaction gas inlet (2) is arranged at the central position of the upper end face of the end cover (1), a support (4) is uniformly distributed on the outer wall of the reaction kettle body (3) in a 360-degree annular array mode in groups of 4, an adjusting bottom plate (5) is installed on the inner wall of the reaction kettle body (3) in a sealing fit mode through a sealing gasket, the head end of a telescopic column (7) is rigidly installed at the central position of the lower end face of the adjusting bottom plate (5) through a rib plate (6), the telescopic column (7) is installed inside a fixed column (8) in a fit mode, a screw groove (9) is arranged in the hollow part of the telescopic column (7), a screw rod (, the sliding chutes (11) are symmetrically arranged at the hollow part in the fixed column (8) in groups of 2, the sliding blocks (12) are arranged in the sliding chutes (11) in a matching way, the sliding blocks (12) are arranged on the outer wall of the bottom of the telescopic column (7) in a rigid and integrated way in groups of 2, the motor groove (13) is arranged at the hollow part in the fixed column (8), the motor (14) is rigidly arranged at the bottom surface of the motor groove (13), the speed reducer (15) is fixedly arranged on the shell of the motor (14) through a speed reducer support, the power input end of the speed reducer (15) is rigidly connected with the power output shaft of the motor (14), the threaded sliding blocks (16) are rigidly arranged on the inner wall of the bottom of the screw groove (9), the threaded sliding blocks (16) are arranged on the screw rods (10) in a matching way, the head end of the U-shaped pipe (17) is rigidly arranged, latex sleeve (19) is inside to be filled with water (20) and to be installed in U-shaped pipe (17), connecting block (21) are installed in latex sleeve (19) right port, stay wire displacement sensor (22) rigid mounting is in the inside mounting groove that sets up of U-shaped pipe (17), stay wire displacement sensor (22) stay wire port connection connecting block (21), cylinder (25) rigidity integral type is installed in U-shaped pipe (17) end, gas-supply pipe (23) rigid mounting is in cylinder (25) bottom lateral wall, baroceptor (24) are installed in cylinder (25) inner wall bottom surface, piston (26) are installed in cylinder (25) inner wall through seal ring sealing fit, fine setting post (27) head end rigid mounting is in piston (26) up end central point and is put, leading truck (28) divide 2 groups to symmetrically rigid mounting in cylinder (25) upper end inner wall, fine setting screw rod groove (29) set up in fine setting post (27) inner hollow department, fine setting screw rod (30) are installed inside fine setting screw rod groove (29), fine setting screw rod (30) rigid mounting is in fine setting reduction gear (33) power take off end, fine setting screw slider (31) cooperation is installed in fine setting screw rod (30), fine setting screw slider (31) rigid mounting is in fine setting screw rod groove (29) terminal inner wall, fine setting slider (32) divide 2 group's rigidity symmetry to be installed in fine setting post (27) terminal outer wall, fine setting reduction gear (33) are fixed in fine setting motor (34) casing through the reduction gear support, fine setting motor (34) are installed in cylinder (25) upper end outer wall through motor support rigid mounting, fine setting reduction gear (33) power take off end rigid connection is in fine setting motor (34) power take off shaft.

2. The apparatus for monitoring the reaction pressure for the research and development of pharmaceutical product raw materials as claimed in claim 1, wherein the rear end side wall of the reaction vessel body (3) is provided with a material taking sealing door.

3. The device for monitoring the reaction pressure for the research and development of the raw materials of the medical products as claimed in claim 1, wherein the air delivery pipe (23) is provided with an electric control valve, and the air delivery pipe (23) is connected with an air pump.

4. The device for monitoring the reaction pressure for the research and development of pharmaceutical product raw materials according to claim 1, wherein the inner wall of the U-shaped tube (17) is coated with lubricating oil.