CN211798963U - Pressurized solid phase extraction device - Google Patents
Pressurized solid phase extraction device Download PDFInfo
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- CN211798963U CN211798963U CN201922207113.XU CN201922207113U CN211798963U CN 211798963 U CN211798963 U CN 211798963U CN 201922207113 U CN201922207113 U CN 201922207113U CN 211798963 U CN211798963 U CN 211798963U
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Abstract
The utility model relates to a pressure solid phase extraction device, which comprises a first bracket, a plurality of solid phase extraction columns, a second bracket, a plurality of receiving containers, a stirring component and a pressure pump; the solid-phase extraction column comprises a solid-phase extraction column body, a partition plate assembly and a pressure ring, the pressure ring is arranged above the filter membrane in a pressing mode, a liquid outlet and an air inlet are formed in the side wall of the solid-phase extraction column body, the liquid outlet is located below the sand core, and the air inlet is located above a liquid level, containing sample liquid, in the solid-phase extraction column body; the baffle sets up in the psammitolite below, and seals between baffle and the solid phase extraction post body inner wall, and the liquid outlet of each solid phase extraction post all is connected with the opening part of the receiving vessel that corresponds through the pipeline, and the air inlet of each solid phase extraction post all is connected with the force pump through the pipeline, and the stirring subassembly is used for stirring the material of this internal splendid attire of solid phase extraction post. The pressurization type solid phase extraction device can effectively avoid the influence on the stability of the detection result caused by the discharge of the adsorption material.
Description
Technical Field
The utility model relates to a solid phase extraction field especially relates to a pressurization formula solid phase extraction device for dispersing solid phase extraction.
Background
The traditional solid phase extraction is to load a solid phase filler in a medical polypropylene column tube, and realize the separation, purification and enrichment of a sample target object through the selective adsorption and desorption process of the solid phase filler on the components of an analysis sample. The method needs to carry out the steps of activating the packing in the column, adding sample, leaching, eluting and the like, and has more operation steps, relatively complex operation and low efficiency.
In order to simplify the operation process and improve the detection efficiency, scientists develop a dispersion solid-phase extraction method, directly add a solid-phase adsorption material into an analysis sample solution, perform centrifugal separation after the solid-phase adsorption material fully adsorbs impurities in sample solution components, suck a supernatant, easily suck the solid-phase adsorption material together in the process of sucking the supernatant, influence the stability of a detection result, and have the problem of low efficiency due to manual suction.
SUMMERY OF THE UTILITY MODEL
Therefore, it is necessary to provide a pressure solid phase extraction apparatus which solves the problems that the efficiency of sucking the supernatant liquid is low and the adsorbing material is easily sucked out together in the dispersed solid phase extraction operation.
In order to achieve the above object, the inventor provides a pressurized solid phase extraction device, comprising a first support, a plurality of solid phase extraction columns, a second support, a plurality of receiving containers, a stirring assembly and a pressure pump;
the solid-phase extraction column comprises a solid-phase extraction column body, a partition plate assembly and a pressing ring, wherein the upper end of the solid-phase extraction column body is provided with an open cylindrical structure, a filter membrane and a sand core matched with an inner cavity of the solid-phase extraction column body are fixed in the solid-phase extraction column body, the pressing ring is pressed above the filter membrane, the filter membrane is attached to the upper end face of the sand core through the pressing ring, a liquid outlet and an air inlet are formed in the side wall of the solid-phase extraction column body, the liquid outlet is located below the sand core, and the air inlet is located above the liquid level;
the partition plate assembly comprises a partition plate and a first power part, the partition plate is arranged below the sand core, the partition plate and the inner wall of the solid-phase extraction column body are sealed, the fixed end of the first power part is fixed below the solid-phase extraction column body, the output end of the first power part is connected with the partition plate, and the first power part is used for pushing the partition plate to move up and down along the inner wall of the solid-phase extraction column body;
a plurality of through holes are formed in the first support and the second support, the solid-phase extraction columns are inserted into the through holes of the first support, the receiving container is inserted into the through holes of the second support, the number of the solid-phase extraction columns is the same as that of the receiving container, the liquid outlets of the solid-phase extraction columns are connected with the opening of the corresponding receiving container through pipelines, the air inlets of the solid-phase extraction columns are connected with the pressure pump through pipelines, and the stirring assembly is used for stirring the substances contained in the solid-phase extraction columns.
Further, the stirring subassembly includes second power spare and stirring vane, the stiff end of second power spare is fixed in solid-phase extraction post body top, and the output of second power spare is connected with stirring vane, stirring vane is used for stirring the internal material of solid-phase extraction post.
Further, still include the lid, the lid is located solid-phase extraction post body opening part, the lid through-hole has been seted up to the lid top, the second power piece sets up in the lid top, and the output of second power piece is provided with the connecting rod, and the connecting rod is inserted and is located in the lid through-hole, and stirring vane is connected to the connecting rod lower extreme.
Further, the pressing ring is an annular structure made of elastic materials and provided with a movable opening.
Further, the sand core and the filter membrane are arranged on the lower portion of the solid phase extraction column body.
Further, the partition plate cross-section is cylindrical structure, and the baffle overcoat is equipped with the sealing washer.
Further, the partition board is made of silica gel or rubber.
Further, a liquid outlet pipe is arranged at the liquid outlet.
Furthermore, an anti-skid washer is arranged in the through hole of the support.
Furthermore, the size of the through hole of the bracket is matched with the outer diameter of the solid-phase extraction column.
Different from the prior art, the technical scheme has the following advantages: after the sample liquid in the solid-phase extraction column body is completely adsorbed by the adsorbing material, the power part is started to conduct the space and the liquid outlet in the solid-phase extraction column body, the pressure pump is started to enable the pressure above the sample liquid to be larger than the pressure at the liquid outlet, the sample liquid in the solid-phase extraction column is pressed out, flows out of the liquid outlet through the filter membrane, and enters the receiving container. The pressurization treatment accelerates the discharge efficiency of the sample liquid, and the treated sample liquid is filtered by the filter membrane and the sand core, so that the influence of the discharge of the adsorption material on the stability of the detection result can be effectively avoided.
Drawings
FIG. 1 is a schematic diagram of a partition plate of a solid-phase extraction column of the present embodiment for blocking a liquid outlet of a solid-phase extraction column body;
FIG. 2 is a schematic diagram of a solid-phase extraction column of the present embodiment in which a partition is separated from a liquid outlet of a solid-phase extraction column body;
FIG. 3 is a schematic diagram of the overall structure of a pressurized solid phase extraction apparatus according to this embodiment.
Description of reference numerals:
1. a first bracket;
2. a second bracket;
21. a receiving container;
3. a pressure pump;
4. a solid phase extraction column;
41. a solid phase extraction column body;
411. a liquid outlet;
412. an air inlet;
42. filtering the membrane;
43. a sand core;
44. a partition plate;
45. a power member;
46. pressing a ring;
51. a second power member;
52. a stirring blade.
Detailed Description
To explain technical contents, structural features, and objects and effects of the technical solutions in detail, the following detailed description is given with reference to the accompanying drawings in conjunction with the embodiments.
Referring to fig. 1 to 3, the present invention provides a pressurized solid phase extraction apparatus, which comprises a first support 1, a plurality of solid phase extraction columns 4, a second support 2, a plurality of receiving containers 21, a stirring assembly and a pressure pump 3, wherein the plurality of solid phase extraction columns are disposed on the first support to achieve the simultaneous dispersed solid phase extraction of the plurality of solid phase extraction columns, thereby improving the efficiency of the dispersed solid phase extraction. Can simultaneously carry out the dispersed solid-phase extraction operation of a plurality of sample liquids in one solid-phase extraction device.
The solid phase extraction post includes solid phase extraction post body 41, baffle subassembly and clamping ring 46, the solid phase extraction post body is provided with the cylindrical structure of open-ended for the upper end, this internal fixed filter membrane 42 and the psammitolite 43 that has inner chamber looks adaptation with it of solid phase extraction post, the filter membrane be the diameter with the same circular structure of solid phase extraction post body internal diameter, the psammitolite is the diameter and the same cylindrical structure of solid phase extraction post body internal diameter, the clamping ring is pressed and is located the filter membrane top, the filter membrane passes through clamping ring and attaches in the psammitolite up end.
In some preferred embodiments, the press ring is an annular structure made of an elastic material and provided with a tap, after the filter membrane is placed into the solid-phase extraction column body, the press ring is placed into the solid-phase extraction column body after being pinched to a size smaller than the pipe orifice of the solid-phase extraction column body, after the press ring is placed into the solid-phase extraction column body, the press ring is enlarged under the action of elastic restoring force of the press ring to be completely attached to the inner wall of the solid-phase extraction column body, and then the press ring is pushed to the upper side of the filter membrane, so that.
A liquid outlet 411 and an air inlet 412 are formed in the side wall of the solid-phase extraction column body, the liquid outlet is located below the sand core, the air inlet is located above the liquid level of the sample liquid contained in the solid-phase extraction column body, and the processed sample liquid is sequentially filtered by the filter membrane and the sand core and then discharged from the liquid outlet of the solid-phase extraction column body. Compressed air of the pressure pump is input into the solid phase extraction column through the pipeline from the air inlet, and sample liquid treated in the solid phase extraction column is discharged into the receiving container in an accelerated manner.
The baffle subassembly includes baffle 44 and first power 45, the baffle sets up in the psammitolite below, and seals between baffle and the solid phase extraction post body inner wall, and after adsorbing material absorbed the work to the appearance liquid and accomplished, the appearance liquid after the processing was from through filter membrane, psammitolite, through the baffle up end, and the gap leakage between baffle and the solid phase extraction post body can not followed to the appearance liquid after the processing. The fixed end of the first power piece is fixed below the solid-phase extraction column body, the output end of the first power piece is connected with the partition plate, and the first power piece is used for pushing the partition plate to move up and down along the inner wall of the solid-phase extraction column body. The first power part is a cylinder, an electric cylinder or a screw rod motor.
A plurality of through-holes have been seted up on the first support, through-hole evenly distributed on first support, the through-hole size and the outer diameter looks adaptation of solid phase extraction post of first support, in the through-hole of first support was located to the solid phase extraction post insertion, the through-hole department of first support was provided with anti-skidding packing ring, after the through-hole of solid phase extraction post inserted first support, anti-skidding packing ring in the support through-hole can prevent effectively that the solid phase extraction post from droing from first support.
The anti-slip receiving device is characterized in that a plurality of through holes are formed in the second support, the through holes are evenly distributed in the second support, the size of the through holes of the second support is matched with the outer diameter of the receiving container, the receiving container is inserted into the through holes of the second support, anti-slip gaskets are arranged at the through holes of the second support, and after the receiving container is inserted into the through holes of the second support, the anti-slip gaskets in the through holes can effectively prevent the receiving container from falling off from the second support.
The number of the solid-phase extraction columns is the same as that of the receiving containers, the liquid outlet of each solid-phase extraction column is connected with the opening of the corresponding receiving container through a pipeline, the air inlet of each solid-phase extraction column is connected with a pressure pump through a pipeline, compressed air output by the pressure pump is input into each solid-phase extraction column through a pipeline branch, and processed sample liquid in the solid-phase extraction column is conveyed into the corresponding receiving container from the liquid outlet of the solid-phase extraction column through a pipeline.
The stirring component is used for stirring the substances contained in the solid-phase extraction column body. The stirring assembly comprises a second power piece 51 and stirring blades 52, the fixed end of the second power piece is fixed above the solid-phase extraction column body, the output end of the second power piece is connected with the stirring blades, and the stirring blades are used for stirring substances in the solid-phase extraction column body. The stirring blade is in a fan blade-shaped structure. In this embodiment, the pressurized solid-phase extraction apparatus further includes a cover body, the cover body is disposed at the opening of the solid-phase extraction column body, a cover body through hole is formed above the cover body, the second power member is disposed above the cover body, a connecting rod is disposed at an output end of the second power member, the connecting rod is inserted into the cover body through hole, and the connecting rod is inserted into the cover body through hole, extends downward and is fixed to the stirring blade. The second power part is a micro motor.
Put into solid phase extraction post this internally with pending appearance liquid and adsorbing material, start second power spare, utilize stirring vane to stir this internal appearance liquid of solid phase extraction post and adsorbing material, adsorption rate of adsorbing material accelerates, after adsorption work, close second power spare, the baffle is located solid phase extraction post body liquid outlet top or just in time is located liquid outlet department this moment, start first power spare, first power spare drives the baffle and moves down, start the force pump, the appearance liquid after this internal processing of solid phase extraction post is impressed from the liquid outlet and is received in the container.
In certain embodiments, the sand core and filter membrane are disposed in a lower portion of the solid phase extraction column body. The space that forms between filter membrane upper surface and the solid phase extraction post body inner wall is used for holding pending appearance liquid and adsorption material, and the usage volume in the solid phase extraction post body can effectively be practiced thrift to psammitolite and filter membrane setting in the lower part of solid phase extraction post body, improves compact structure nature.
In some embodiments, the baffle cross-section is cylindrical structure, and the diameter of baffle is less than solid phase extraction post body inner wall diameter, and the baffle overcoat is equipped with the sealing washer, and baffle and solid phase extraction post body inner wall looks adaptation behind the sealing washer are established to the cover, and the sealing washer can effectively avoid at the in-process that the baffle reciprocated, and sample liquid leaks downwards from the gap between baffle and the solid phase extraction post body.
In a more preferred embodiment, the partition is made of silicone or rubber. The baffle variability degree that silica gel or rubber were made is big, when needs were cleaned solid phase extraction post body inner wall, thereby can follow this internal extraction of solid phase extraction post with the baffle and clean solid phase extraction post body inner wall, and the operation of repeatedly taking out or putting into also is difficult for causing the deformation to the baffle.
In some embodiments, a liquid outlet pipe is arranged at the liquid outlet, and the pipeline is connected with the liquid outlet pipe and communicated with the filter flask.
It should be noted that, although the above embodiments have been described herein, the scope of the present invention is not limited thereby. Therefore, based on the innovative concept of the present invention, the changes and modifications of the embodiments described herein, or the equivalent structure or equivalent process changes made by the contents of the specification and the drawings of the present invention, directly or indirectly apply the above technical solutions to other related technical fields, all included in the protection scope of the present invention.
Claims (10)
1. A pressure solid phase extraction device is characterized in that: comprises a first bracket, a plurality of solid phase extraction columns, a second bracket, a plurality of receiving containers, a stirring component and a pressure pump;
the solid-phase extraction column comprises a solid-phase extraction column body, a partition plate assembly and a pressing ring, wherein the upper end of the solid-phase extraction column body is provided with an open cylindrical structure, a filter membrane and a sand core matched with an inner cavity of the solid-phase extraction column body are fixed in the solid-phase extraction column body, the pressing ring is pressed above the filter membrane, the filter membrane is attached to the upper end face of the sand core through the pressing ring, a liquid outlet and an air inlet are formed in the side wall of the solid-phase extraction column body, the liquid outlet is located below the sand core, and the air inlet is located above the liquid level;
the partition plate assembly comprises a partition plate and a first power part, the partition plate is arranged below the sand core, the partition plate and the inner wall of the solid-phase extraction column body are sealed, the fixed end of the first power part is fixed below the solid-phase extraction column body, the output end of the first power part is connected with the partition plate, and the first power part is used for pushing the partition plate to move up and down along the inner wall of the solid-phase extraction column body;
a plurality of through holes are formed in the first support and the second support, the solid-phase extraction columns are inserted into the through holes of the first support, the receiving container is inserted into the through holes of the second support, the number of the solid-phase extraction columns is the same as that of the receiving container, the liquid outlets of the solid-phase extraction columns are connected with the opening of the corresponding receiving container through pipelines, the air inlets of the solid-phase extraction columns are connected with the pressure pump through pipelines, and the stirring assembly is used for stirring the substances contained in the solid-phase extraction columns.
2. A pressurized solid phase extraction apparatus according to claim 1, wherein: the stirring assembly comprises a second power part and stirring blades, the fixed end of the second power part is fixed above the solid-phase extraction column body, the output end of the second power part is connected with the stirring blades, and the stirring blades are used for stirring substances in the solid-phase extraction column body.
3. A pressurized solid phase extraction apparatus according to claim 2, wherein: the solid-phase extraction column comprises a solid-phase extraction column body, and is characterized by further comprising a cover body, wherein the cover body is covered on the opening of the solid-phase extraction column body, a cover body through hole is formed in the upper portion of the cover body, the second power piece is arranged above the cover body, a connecting rod is arranged at the output end of the second power piece, the connecting rod is inserted into the cover body through hole, and the lower end of.
4. A pressurized solid phase extraction apparatus according to claim 1, wherein: the press ring is an annular structure which is made of elastic materials and provided with a movable opening.
5. A pressurized solid phase extraction apparatus according to claim 1, wherein: the sand core and the filter membrane are arranged at the lower part of the solid phase extraction column body.
6. A pressurized solid phase extraction apparatus according to claim 1, wherein: the cross-section of the partition plate is of a cylindrical structure, and a sealing ring is sleeved outside the partition plate.
7. A pressurized solid phase extraction apparatus according to claim 1, wherein: the partition plate is made of silica gel or rubber.
8. A pressurized solid phase extraction apparatus according to claim 1, wherein: a liquid outlet pipe is arranged at the liquid outlet.
9. A pressurized solid phase extraction apparatus according to claim 1, wherein: and an anti-skid washer is arranged in the through hole of the bracket.
10. A pressurized solid phase extraction apparatus according to claim 1, wherein: the size of the through hole of the bracket is matched with the outer diameter of the solid-phase extraction column.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922207113.XU CN211798963U (en) | 2019-12-11 | 2019-12-11 | Pressurized solid phase extraction device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922207113.XU CN211798963U (en) | 2019-12-11 | 2019-12-11 | Pressurized solid phase extraction device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211798963U true CN211798963U (en) | 2020-10-30 |
Family
ID=73140157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201922207113.XU Active CN211798963U (en) | 2019-12-11 | 2019-12-11 | Pressurized solid phase extraction device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN211798963U (en) |
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2019
- 2019-12-11 CN CN201922207113.XU patent/CN211798963U/en active Active
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