CN211741322U

CN211741322U - Blood analyzer and optical detection cell

Info

Publication number: CN211741322U
Application number: CN201922133484.8U
Authority: CN
Inventors: 郭俊游
Original assignee: Shenzhen Dymind Biotechnology Co Ltd
Current assignee: Shenzhen Dymind Biotechnology Co Ltd
Priority date: 2019-11-30
Filing date: 2019-11-30
Publication date: 2020-10-23
Anticipated expiration: 2029-11-30

Abstract

The utility model provides a blood analysis appearance and optical detection pond, this optical detection pond include cell body and light-passing board, the cell body be equipped with through the groove and with the notes liquid passageway that link up the groove intercommunication, the light-passing board is fixed mutually with the cell body and seals the outer end that links up the groove. The utility model provides an optical detection pond adopts components of a whole that can function independently to process and makes the back equipment again, very big simplification the processing degree of difficulty, improved machining efficiency, reduced and generated this.

Description

Blood analyzer and optical detection cell

Technical Field

The utility model relates to a sample analysis technical field, in particular to blood cell analyzer, optical detection pond.

Background

Blood analyzers are widely used in hospitals of all levels, medical testing laboratories and regional detection centers due to their high measurement speed, high accuracy and small reagent consumption. Be equipped with detection device in the full autoanalyzer, detection device detects the sample in the optical detection pond through the optical detection mode.

However, the optical detection cell in the existing detection device is usually formed by integrally forming glass, which has high processing difficulty, resulting in low processing efficiency and high product price.

SUMMERY OF THE UTILITY MODEL

The application provides a blood cell analyzer, optical detection pond to solve the higher problem of the optical detection pond integrated into one piece processing degree of difficulty among the prior art.

In order to solve the technical problem, the application adopts a technical scheme that: an optical detection cell for a blood analyzer is provided, the optical detection cell comprising:

the device comprises a tank body and a liquid inlet pipe, wherein the tank body is provided with a through groove and a liquid injection channel communicated with the through groove;

and the light-transmitting plate is fixed with the tank body and closes the outer end of the through groove.

In order to solve the above technical problem, another technical solution adopted by the present application is: there is provided a blood cell analyzer comprising the aforementioned optical detection cell.

The beneficial effect of this application is: be different from prior art's condition, the utility model provides an optical detection pond adopts components of a whole that can function independently manufacturing after the equipment again, very big simplification the processing degree of difficulty, improved machining efficiency, reduced and generated this.

Drawings

FIG. 1 is a schematic view of a partial plan view of the interior of an analyzer provided by an embodiment of the present invention;

FIG. 2 is a schematic perspective view of a detection device of the analyzer shown in FIG. 1;

FIG. 3 is a schematic view of a partial perspective structure of the interior of an analyzer provided by an embodiment of the present invention;

FIG. 4 is a schematic perspective view of a heating assembly of the detection apparatus shown in FIG. 2;

FIG. 5 is an exploded view of the heating assembly shown in FIG. 4;

FIG. 6 is a schematic perspective view of a heating block of the heating assembly shown in FIG. 5;

FIG. 7 is a schematic perspective view of a detection assembly of the detection apparatus shown in FIG. 2;

FIG. 8 is a schematic diagram of an exploded view of the detection assembly shown in FIG. 7;

FIG. 9A is a schematic perspective view of an optical detection cell of the detection apparatus shown in FIG. 2;

FIG. 9B is a schematic diagram of an exploded structure of the optical detection cell shown in FIG. 9A;

FIG. 10A is a schematic side view of another embodiment of an optical detection cell;

FIG. 10B is a schematic cross-sectional view of the optical detection cell shown in FIG. 10A;

FIG. 10C is a schematic diagram of a side view of another embodiment of an optical detection cell;

FIG. 10D is a schematic view of the optical detection cell shown in FIG. 10C on the other side;

FIG. 11 is a schematic perspective view of a mounting cup of the analyzer shown in FIG. 1;

FIG. 12 is an exploded view of the mounting cup shown in FIG. 11;

FIG. 13 is a side view of the mounting socket shown in FIG. 11;

FIG. 14 is a schematic perspective view of the mixing tank shown in FIG. 12;

FIG. 15 is a schematic cross-sectional view of the mixing tank shown in FIG. 14;

FIG. 16 is an exploded schematic view of the pre-heat tank shown in FIG. 12;

fig. 17 is a schematic perspective view of a bobbin according to an embodiment of the present invention;

fig. 18 is a side view of the bobbin cartridge shown in fig. 17;

FIG. 19 is a schematic perspective view of a heating assembly for a pipeline according to an embodiment of the present invention;

FIG. 20 is a cross-sectional structural schematic view of the pipe heating assembly shown in FIG. 19;

FIG. 21 is an exploded view of the pipe heating assembly shown in FIG. 19;

FIGS. 22-26 are schematic structural views of a detection assembly provided by embodiments of the present invention;

fig. 27-30 are simplified structural diagrams of a detection apparatus according to an embodiment of the present invention.

Detailed Description

The technical solutions between the following embodiments can be combined with each other.

In a first embodiment, this embodiment provides a detection apparatus, as shown in fig. 1 to 6, the detection apparatus includes a stand 100, a heating component, a detection component, and an optical detection cell 120.

As shown in fig. 2, the vertical frame 100 may be a metal support or a plastic support, and is fixedly assembled in the housing of the analyzer, the heating assembly may be obliquely fixed on the vertical frame 100, the heating assembly includes a heating block 110, the heating block 110 may be made of aluminum material or copper material, the heating block 110 is provided with a plurality of assembling cavities 113 for receiving the optical detection cell 120, the volume of the assembling cavities 113 matches with the volume of the optical detection cell 120, the assembling cavities 113 fully surround the optical detection cell 120, only the bottom end surface of the optical detection cell 120 is exposed, the contact area between the heating block 110 and the optical detection cell 120 is large, the heat conduction effect is good, and the liquid to be detected in the optical detection cell 120 can be well temperature controlled. The detection component is fixed with the heating block 110, the detection component comprises a base body 130, the base body 130 is provided with a notch 134 matched with the heating block 110 in a clamping mode, and the optical detection cell 120 is arranged in the notch 134 and is loaded into the assembly cavity 113 through the bearing of the base body 130.

As shown in fig. 2, 7, and 8, the heating block 110 further has a light through hole 114 penetrating through the assembling cavity 113, the substrate 130 further has a light incident channel 133, a first light emitting channel 131, and a second light emitting channel 132, the gap 134 is disposed between the light incident channel 133 and the first light emitting channel 131 and the second light emitting channel 132, the light incident channel 133 is aligned with the first light emitting channel 131, an axis of the second light emitting channel 132 is inclined with respect to an axis of the first light emitting channel 131, and the light through hole 114 is aligned with the light incident channel 133 when the detecting assembly is fixed to the heating block 110.

In order to fix the detecting element and the heating block 110, the base 130 has an assembling plate 136 integrally extending from one side of the notch 134 close to the light inlet channel 133, the assembling plate 136 has a first assembling hole 137, a first connecting hole 111 is formed in a side wall of the heating block 110 corresponding to the first assembling hole 137, the detecting element can be locked with respect to the heating block 110 by passing a screw through the first assembling hole 137 and screwing into the first connecting hole 111, and the first connecting hole 111 is located at a side edge of the light through hole 114.

Further, the base 130 is further provided with a second assembling hole 138 penetrating to the bottom of the notch 134, a second connecting hole 112 is formed at the bottom end of the heating block 110 corresponding to the second assembling hole 138, the detection assembly can be locked with respect to the heating block 110 by passing a screw through the second assembling hole 138 and screwing the screw into the second connecting hole 112, and the second connecting hole 112 is located at the side of the assembling cavity 113.

In the embodiment of the present invention, the assembly cavity 113 is provided with a plurality of parallel spaced-apart cavities, for example, 6 cavities as shown in fig. 2, the detection assembly and the optical detection cell 120 are all provided with a plurality of groups of guide ribs 115, the side wall of the heating block 110 is further provided with a plurality of groups of guide ribs 115 at parallel spaced-apart intervals, so that the notch 134 and the assembly plate 136 of the base 130 are aligned, clamped and matched with the heating block 110, and the extending direction of the guide ribs 115 is parallel to the extending direction of the assembly cavity 113.

As shown in fig. 2 and 4 to 10, the detection device further includes a waterproof sealing ring 101, the optical detection cell 120 includes a cell body 121 and a liquid injection tube 125, a through hole 116 is formed at the top end of the heating block 110 and is communicated with the assembly cavity 113 to allow the liquid injection tube 125 to extend out, the waterproof sealing ring 101 is located in the assembly cavity 113, is sleeved on the periphery of the liquid injection tube 125, and is sandwiched between the optical detection cell 120 and the heating block 110, so that external liquid can be prevented from entering the optical detection cell 120 to affect the detection result.

As shown in fig. 1 and 2, the heating block 110 is obliquely fixed on the vertical frame 100 so that the assembly chamber 113 is obliquely arranged, and the optical detection cell 120 and the detection assembly are obliquely arranged relative to the horizontal plane.

The detection device further comprises a pipeline heating assembly 300, the pipeline heating assembly 300 is used for winding a pipeline and heating the pipeline, the vertical frame 100 comprises a first support arm 102 and a second support arm 104, the heating block 110 is fixed through the first support arm 102, the pipeline heating assembly 300 is arranged on the side edge of the heating block 110 through the second support arm 104, and the pipeline heating assembly 300 is lower than the liquid injection pipe 125, so that the pipeline wound on the pipeline heating assembly 300 can be bent and butted with the liquid injection pipe 125 with smaller curvature when being led out, the bubble discharge can be facilitated, the bubble problem can be reduced, if the pipeline heating assembly 300 is higher than the liquid injection pipe 125, the pipeline wound on the pipeline heating assembly 300 is bent with larger curvature and butted with the liquid injection pipe 125 when being led out, the bubbles are not easy to discharge, and the relatively serious bubble problem can be generated.

As shown in fig. 4 to 6, the heating assembly further includes a heating film 117, a temperature sensor 118 and an over-temperature protection switch 119, the heating block 110 may be made of a material with good thermal conductivity, such as aluminum or copper, the heating film 117 is attached to the surface of the heating block 110, and the temperature sensor 118 and the over-temperature protection switch 119 are embedded in the heating block 110. The two ends of the heating block 110 can be provided with mounting holes 103 to be fixed with the first support arm 102 of the stand 100, the surface of the heating block 110 for attaching the heating film 117 can be provided with a protrusion 106, the protrusion 106 enables the cross section of the heating block 110 to be L-shaped, and the over-temperature protection switch 119 can be embedded in the protrusion 106, so that the structure of the heating block 110 can be compact.

The detection device provided by the embodiment has a novel structure, the optical detection cell 120 is arranged in the notch part 134 and is loaded into the assembly cavity through the support of the base body 130, the assembly and disassembly are convenient, the maintenance is facilitated, the influence of water leakage on the detection device can be reduced, and the problem of bubbles can be reduced. The embodiment also provides a sample analyzer, which comprises the detection device.

In a second embodiment, this embodiment provides a detection assembly, as shown in fig. 7 to 8, the detection assembly includes a base 130, a light receiver, and a fixing assembly. In one embodiment, the securing assembly includes a securing member 139 and a sealing ring 140.

The base 130 may be made of plastic or metal, the fixing element 139 is fixed to the base 130 to assemble the light receiver in the base 130, and the sealing ring 140 is sandwiched between the fixing element 139 and the light receiver.

Specifically, as shown in fig. 8, the base 130 is provided with a first light-emitting channel 131 and a second light-emitting channel 132, an axis of the second light-emitting channel 132 is inclined with respect to an axis of the first light-emitting channel 131, side edges of the first light-emitting channel 131 and the second light-emitting channel 132 are provided with a first fixing hole 143, and the fixing member 139 is a fixing plate fixed to the base 130 by a screw.

The light receiver comprises a first photodiode 141 and a second photodiode 142, the first photodiode 141 is assembled in the first light-emitting channel 131, the second photodiode 142 is assembled in the second light-emitting channel 132, the detection assembly further comprises a transmission light filtering block 144, a lens fixing block 145 and a lens 146, the transmission light filtering block 144 is arranged in the first light-emitting channel 131 and located on the light-in side of the first photodiode 141, the lens fixing block 145 and the lens 146 are arranged in the second light-emitting channel 132, and the lens 146 is fixed by the lens fixing block 145 and located on the light-in side of the second photodiode 142.

The base 130 is further provided with a notch 134, the notch 134 is communicated with the first light-emitting channel 131 and the second light-emitting channel 132, the notch 134 is used for accommodating the optical detection cell 120, one side of the notch 134, which is close to the first light-emitting channel 131 and the second light-emitting channel 132, is provided with an arc-shaped groove 135, the side of the arc-shaped groove 135 is provided with a second fixing hole 147, the second fixing hole 147 is used for fixing a light barrier (not shown), and the light barrier is used for blocking light at two ends of the arc-shaped groove 135.

The detecting assembly further includes a first light barrier 148, the first light barrier 148 is fixed to the substrate 130 and extends into the gap 134 near one side of the first light-emitting channel 131 and the second light-emitting channel 132, the first light barrier 148 is provided with a light-passing groove 149, and the light-passing groove 149 is opposite to the first light-emitting channel 131 and the second light-emitting channel 132.

Base member 130 has assembly plate 136 in the integrative extension of one side that first light-emitting channel 131 and second light-emitting channel 132 were kept away from to breach portion 134, is equipped with first pilot hole 137 on assembly plate 136, and first pilot hole 137 is used for supporting base member 130 fixed mounting, and it is easy to know to combine fig. 2, and assembly plate 136 can with the spout sliding fit that two guide ribs 115 constitute, passes first pilot hole 137 and screw in first connecting hole 111 through the screw and can lock the relatively heating piece 110 of detecting component.

As shown in fig. 8, the detecting assembly further includes a laser 156 and a second diaphragm 150, the substrate 130 is further provided with a light inlet channel 133, the light inlet channel 133 is communicated with the notch 134 and aligned with the first light outlet channel 131, and the laser 156 and the second diaphragm 150 are installed in the light inlet channel 133. The number of the second light barriers 150 may be one, two, or three, and the first light barrier 148 and the second light barrier 150 function such that the light-transmitting portions function as light-transmitting portions and the light-blocking portions function as light-blocking portions.

As shown in fig. 2, 7 and 8, the base 130 is further provided with a first slot 151 and a second slot 152, the first slot 151 is disposed near the outer end of the light-entering channel 133 so that one end of the base 130 constitutes a clamping block 153, the second slot 152 is disposed on the clamping block 153 and communicates with the light-entering channel 133, both sides of the clamping block 153 are provided with through connection holes 154, and the connection holes 154 are used for setting screws so that the clamping block 153 clamps or releases the laser 156.

As shown in fig. 7 and 8, the fixing plate is provided with a slot 155 to allow lead wires of the first photodiode 141 and the second photodiode 142 to be drawn out.

The detection assembly provided by the embodiment can improve the assembly precision by arranging the sealing ring 140 between the fixing member 139 and the light receiver, so that the receiving plane of the light receiver is relatively flat.

In another embodiment, the fixing component is a small circuit board, the optical receiver is soldered on one surface of the circuit board, the circuit board is fixed with the base 130 by a screw or an adhesive, the other surface of the circuit board is provided with a terminal, and a signal of the optical receiver can be led out through the terminal and is connected to the main control circuit board of the analyzer for processing through a wire. The present embodiment also provides a sample analyzer, which includes the aforementioned detection assembly.

Third embodiment, as shown in fig. 9A and 9B, the present embodiment provides an optical detection cell 120, where the optical detection cell 120 includes a cell body 121 and a light-transmitting plate 124.

The cell body 121 is provided with a straight through groove 122 penetrating two opposite surfaces of the cell body 121 and a liquid injection passage 123 communicating with the through groove 122, and the light-transmitting plate 124 is fixed with the cell body 121 and closes the outer end of the through groove 122. The optical detection tank 120 is designed in a split mode, so that the problem that the difficulty is high in glass integrated design and manufacturing can be solved, specifically, the through groove 122 of the tank body 121 can be formed directly in a numerical control drilling or numerical control groove milling mode, and the liquid injection channel 123 can be formed in a numerical control drilling mode.

Specifically, the tank body 121 may be a metal tank body, a ceramic tank body, a glass tank body or a plastic tank body. The transparent plate 124 may be a glass plate or a plastic plate. The light-transmitting plate 124 and the cell body 121 can be fixed by adhesive bonding, laser welding or screws.

Cell body 121 may be provided with a raised post, a rib 126, a surrounding edge or a recessed area to position and fit light-transmitting plate 124, and rib 126 may be a straight strip or L-shaped as shown in fig. 10.

In an embodiment, the optical detection cell 120 may have a rectangular shape, the optical detection cell 120 has a pair of first side surfaces, a pair of second side surfaces and a pair of third side surfaces, the area of the first side surfaces is gradually reduced, the through slot 122 penetrates through the pair of first side surfaces, and the outer opening end of the liquid injection channel 123 is located on one of the third side surfaces.

Cell body 121 is equipped with two notes liquid passageway 123, and two notes liquid passageway 123 are vertical setting and are close to the relative end angle setting of third surface respectively in order to reduce the product volume. The two liquid injection channels 123 are respectively connected with a liquid injection pipe 125.

The cross section of the through groove 122 may be circular, oval, racetrack-shaped, rectangular, or regular polygon, and the racetrack-shaped is a shape surrounded by two parallel sides and two arc sides.

The optical detection cell 120 provided by the embodiment is assembled after being manufactured by adopting split type machining, so that the machining difficulty is greatly simplified, the machining efficiency is improved, the production cost is reduced, and the problem of high difficulty in design and manufacture by adopting a glass integrated mode can be avoided.

As shown in fig. 10A and 10D, the present embodiment further provides an optical detection cell, which includes a cell body 121, a light-transmitting plate (not shown, refer to the light-transmitting plate 124) and a liquid injection tube 125.

The cell body 121 is provided with a straight through groove 122 penetrating two opposite surfaces of the cell body 121, a liquid injection channel (not shown, refer to the liquid injection channel 123) communicating with the through groove 122, an open end of the liquid injection channel being located on an adjacent surface between the two opposite surfaces, and a liquid guide groove 127. The through groove 122 of the cell body 121 can be directly formed in a numerical control drilling or numerical control groove milling mode, the liquid injection channel 123 can be formed in a numerical control drilling mode, the liquid guide groove 127 can be formed in a numerical control groove milling mode, and the cell body is convenient to machine, regular in shape and high in precision.

The tank body 121 may be a metal tank body 121, a ceramic tank body 121, a glass tank body 121 or a plastic tank body 121. Cell body 121 may be rectangular in shape, or may be stepped as shown in fig. 10B and 10C, i.e., including a relatively thin lower portion and a relatively thick upper portion. The cross section of the through-groove 122 may be in a racetrack shape as shown in fig. 10A, the areas of both ends of the through-groove 122 may be the same or different, the bottom side of the through-groove 122 in the longitudinal section of the through-groove 122 is disposed horizontally or obliquely as shown in fig. 10B, in other embodiments, the cross section of the through-groove 122 may be in a circular hole shape (as shown in fig. 10D) or a square hole shape, when the areas of both ends of the through-groove 122 are different, for example, when the longitudinal section of the through-groove 122 shown in fig. 10A and 10B is in a right trapezoid shape, the internal volume of the optical detection cell may be reduced to prevent bubbles from being generated, the angle of the oblique side of the through-groove 122 is the same as the angle of the scattered light, the scattered light may be emitted through the aforementioned second light-emitting channel 132, the angle may effectively block the stray light, and the range of the included angle of the bottom side of the through-groove, 23.5 degrees, 24 degrees, 26 degrees, 28 degrees, etc. The through groove 122 may be disposed at a thinner lower portion of the cell body 121, and an area of the corresponding light transmitting plate may be reduced to form flush assembly with the cell body 121 in a stepped shape.

The liquid guide groove 127 connects the through groove 122 with the liquid injection passage, the liquid guide groove 127 is connected with the liquid injection passage in an inclined manner, the liquid guide groove 127 is connected with the top end of the through groove 122 so as to facilitate the discharge of bubbles in the tank body 121, and the angle range of an acute angle formed by the liquid guide groove 127 relative to the vertical direction is less than or equal to 30 degrees, such as 23 degrees, 24 degrees, 25 degrees, 26 degrees, 27 degrees and the like. Liquid guide groove 127 sinks on two opposite surfaces of cell body 121, one end of liquid guide groove 127 is communicated with the end of through groove 122, the other end of liquid guide groove 127 is communicated with liquid injection channel, liquid injection channel is connected with liquid injection pipe 125, liquid injection pipe 125 and through groove 122 can be arranged in a staggered manner, so that liquid guide groove 127 communicated with liquid injection channel through groove 122 can be arranged in an inclined manner, the obliquely arranged liquid guide groove can enable bubbles to be difficult to accumulate in cell body 121, and liquid injection channel and liquid injection pipe 125 are two in number and arranged diagonally so as to enable the structure of the product to be compact.

The light-transmitting plate is fixed with the cell body 121 and closes the outer end of the through groove 122. The light-transmitting plate is a glass plate or a plastic plate. The light-transmitting plate and the cell body 121 are fixed by adhesive bonding, laser welding or screws. The cell body 121 may be provided with a convex pillar, a rib, a surrounding edge or a concave area for positioning and assembling the light transmission plate.

The optical detection pool 120 of the embodiment adopts a split design, so that the problem of high difficulty in design and manufacture of a glass integrated type can be avoided, the accurate control of the volume and the shape of the inner cavity of the optical detection pool 120 is facilitated, the requirements of the shape rule and the small volume of the inner cavity and the requirements of the local inclined plane of the inner cavity are easily met, the generation difficulty and the cost are reduced, the bubble influence is reduced by the optimized structural design, the detection condition is optimized, and the detection precision is improved.

This embodiment still provides a sample analyzer, and this sample analyzer includes aforementioned optical detection pond 120, mixing pond and determine module, and mixing pond and optical detection pond intercommunication, determine module are equipped with the breach portion of holding optical detection pond, and determine module still includes laser instrument and the photoreceiver of locating breach portion both sides respectively. The mixing pool and the detection component refer to other embodiments.

A fourth embodiment, this embodiment provides an assembly seat, as shown in fig. 11 to 16, the assembly seat includes a first assembly body 210, two surfaces of the first assembly body 210 facing away from each other are respectively provided with a first assembly groove 211 and a second assembly groove 212, the first assembly groove 211 and the second assembly groove 212 are respectively used for arranging a blending pool 240 and a preheating pool 250, the number of the first assembly groove 211 and the second assembly groove 212 may be single or laterally expanded into a plurality (for example, 6 as shown in fig. 12), and the position of the first assembly groove 211 is higher than that of the second assembly groove 212 so that the blending pool 240 is arranged higher than the preheating pool 250. The liquid in the preheating tank 250 needs to be input into the blending tank 240 for reaction, and when bubbles are generated by heating the liquid in the preheating tank 250, the bubbles in the preheating tank 250 are easily discharged out of the preheating tank 250 along with the output of the liquid under the condition that the blending tank 250 is higher than the preheating tank 250 due to the lower density of the bubbles.

As shown in fig. 13, the first assembly body 210 is stepped and includes a connection portion 214, a first fitting portion 216 extending upward from one side of the connection portion 214, and a second fitting portion 218 extending downward from the other side of the connection portion 214, the first fitting groove 211 is recessed in the first fitting portion 216 and the connection portion 214, and the second fitting groove 212 is recessed in the second fitting groove 212 and the connection portion 214.

As shown in fig. 12, the assembly base further includes a second assembly body 220 and a third assembly body 230, the second assembly body 220 is provided with a third assembly groove 221 and is fastened with the first assembly groove 211 to set up a blending tank 240, and the third assembly body 230 is provided with a fourth assembly groove 231 and is fastened with the second assembly groove 212 to set up a preheating tank 250. The first assembly 210, the second assembly 220, and the third assembly 230 are made of aluminum material or copper material with good thermal conductivity.

Of course, in other embodiments, the mounting seat may be a single component, and the first mounting groove 211 and the second mounting groove 212 are cavities disposed inside the first assembly 210 and matched with the blending pool 240 and the preheating pool 250, so as to reduce material cost.

As shown in fig. 12, this embodiment further provides a heating assembly, which includes a blending pool 240, a preheating pool 250, a first heating body 261, a second heating body 262 and the aforementioned assembly seat, where the blending pool 240 and the preheating pool 250 are made of corrosion-resistant materials, the blending pool 240, the preheating pool 250 and the assembly seat are filled with heat-conducting materials, and the first heating body 261 and the second heating body 262 are respectively used for heating the blending pool 240 and the preheating pool 250.

As shown in fig. 14 and 15, a first liquid outlet pipe 241 and a waste discharge pipe 242 are disposed at the bottom of the mixing tank 240, a first liquid inlet pipe 243 is disposed at a position of the mixing tank 240 close to the top, and a first reinforcing block 244 and a second reinforcing block 245 are further disposed at the first liquid outlet pipe 241 and the first liquid inlet pipe 243 of the mixing tank 240, respectively. When the blending tank 240 is not used, the blending tank needs to be soaked with liquid, and if the position of the first liquid inlet pipe 243 is low, the liquid in the blending tank 240 is easy to contact with the reagent in the first liquid inlet pipe 243 to pollute the reagent, so the installation position of the first liquid inlet pipe 243 is higher than the height of the soaking liquid.

The first liquid inlet pipe 243 is obliquely arranged relative to the blending pool 240, and the included angle of the first liquid inlet pipe 243 relative to the axis of the blending pool 240 can be 30 +/-15 degrees.

The bottom of the preheating tank 250 is provided with a second liquid inlet pipe 251, the top of the preheating tank 250 is provided with a second liquid outlet pipe 252, and the position of the second liquid outlet pipe 252 is lower than that of the first liquid inlet pipe 243. The top of the preheating tank 250 is also provided with a plug body 253.

The heating element still includes excess temperature protection switch 263, temperature sensor 264, first installing support, second installing support and top cap 276, excess temperature protection switch 263, temperature sensor 264 is installed in first assembly body 210, first installing support is including the first connecting plate 271 that connects gradually, second connecting plate 272 and third connecting plate 273, first connecting plate 271 is connected with first assembly body 210 and is parallel with third connecting plate 273, the second installing support includes fourth connecting plate 274 and fifth connecting plate 275 that the cross-section is L connection, fourth connecting plate 274 with be used for the bearing and connect the bottom of first assembly body 210, fifth connecting plate 275 and third connecting plate 273 are located the coplanar, conveniently carry out fixed mounting, be equipped with on the top cap 276 with fixed orifices 213, the fixed orifices 278 that 232 corresponds and the perforation 277 that corresponds with the second drain pipe 252 that preheats the pond.

The heating element that this embodiment provided compact structure, convenient assembling, heat conduction efficiency is better, the first feed liquor pipe 243 of mixing pond 240 sets up the position relatively higher and be the slope setting, reagent is difficult for receiving the pollution, the reagent of entering is difficult for spattering on the pool wall of mixing pond 240, through first heating member 261, second heating member 262 is respectively to mixing pond 240, preheat pond 250 and heat, can control different heating power, reach different heating effects, and then improve the accuracy that detects. The present embodiments also provide a sample analyzer that includes the aforementioned heating assembly.

In a fifth embodiment, the present embodiment provides a pipeline heating assembly 300, as shown in fig. 17 to 21, the pipeline heating assembly 300 includes a heating cylinder 301, a pipe penetrating channel 302 penetrating through an arc-shaped wall of the heating cylinder 301 is provided on an outer circumferential surface of the heating cylinder 301, the outer circumferential surface of the heating cylinder 301 is used for winding a pipeline, and the pipe penetrating channel 302 is used for allowing the pipeline to pass through and forming an anti-drop limit for the pipeline.

The tube-passing channel 302 may be a straight strip or a curved strip. The tube passing channel 302 is away from the diameter of the heating cartridge 301 and close to the outer circumferential surface of the heating cartridge 301. If the tube-through channel 302 is directly opened on the diameter of the heating cylinder 301, the tube-through channel may be bent at a larger angle, which is not favorable for the transmission of the internal reagent.

The opening size of poling passageway 302 one end is greater than the opening size of the other end so that carry out the poling operation, penetrates convenient operation from the great one end of opening to it is better to wear out spacing effect from the less one end of opening.

The heating cylinder 301 is provided with a plurality of flanges 303, for example, three flanges are shown in fig. 17, the pipe penetrating channels 302 are arranged close to the flanges 303, two pipe penetrating channels 302 are arranged between two adjacent flanges to wind a coil of pipeline, two leading-out ends of the pipeline penetrate through the two pipe penetrating channels 302 respectively, and the pipeline can be well prevented from loosening.

As shown in fig. 21, the pipe heating assembly 300 further includes a fixing clip 310, the fixing clip 310 is disposed on the outer periphery of the heating cylinder 301 and is provided with an opening 312 corresponding to the pipe passing passage 302 to allow the pipes (304, 305) to be led out. The stationary clamping plate 310 may be two, and each stationary clamping plate 310 may include an arc-shaped portion and a flat plate portion, and the flat plate portion may be provided with a locking hole for locking a screw. The pipeline heating assembly 300 further comprises heat insulation cotton 330, the heat insulation cotton 330 is sleeved on the periphery of the fixed clamping plate 310 and provided with a cut part 332 corresponding to the opening 312 to allow the pipelines (304, 305) to be led out, one end of the heat insulation cotton 330 is further provided with extension cotton 334, the extension cotton 334 at least partially covers the end part of the heating cylinder 301 to improve the heat insulation effect, and meanwhile, the extension cotton 334 can play a role in limiting assembly, so that the heat insulation cotton 330 and the fixed clamping plate 310 are not easy to relatively displace.

The pipe heating assembly 300 further includes a temperature protection switch 342, a temperature sensor 344, and a heating rod 346, and an end of the heating cartridge 301 is provided with a fitting groove 341, and the fitting groove 341 is used to fit the temperature protection switch 342, the temperature sensor 344, and the heating rod 346. The pipe heating assembly 300 further includes a mounting plate 350, and the mounting plate 350 is fixed to one end of the heating cartridge 301 for fixedly assembling the heating cartridge 301.

The pipeline heating assembly 300 that this embodiment provided can carry out accurate control by temperature change on reagent delivery path, has avoided reagent heat loss in transportation process, has improved heating efficiency and detection precision. The present embodiment also provides a sample analyzer comprising the aforementioned tube heating assembly 300.

In a sixth embodiment, this embodiment provides a detection apparatus, as shown in fig. 1 to 12, the detection apparatus includes a blending tank 240, a preheating tank 250, a diluent tank 270, an optical detection tank 120, a first heating body 261, a second heating body 262, a third heating body 263, and a heating component.

Wherein, the first heating body 261 is attached to the outer side of the blending pool 240 and used for heating the blending pool 240, the preheating pool 250 is arranged at the side edge of the blending pool 240 and communicated with the blending pool 240 through a pipeline, the second heating body 262 is attached to the outer side of the preheating pool 250 and used for heating the preheating pool 250, the diluent pool 270 is arranged at the side edge of the blending pool 240 and communicated with the blending pool 240 through a pipeline, the third heating body 263 is attached to the outer side of the diluent pool 270 and used for heating the diluent pool 270,

the optical detection cell 120 is arranged on the side of the blending cell 240 and is communicated with the blending cell 240 through a pipeline, the heating component comprises a heating block 110, and the heating block 110 coats the outer side of the optical detection cell 120 and is used for heating the optical detection cell 120.

As shown in fig. 17 to 21, the detection assembly further includes a pipeline heating assembly 300, and the pipeline heating assembly 300 includes a heating cylinder 301, and an outer circumferential surface of the heating cylinder 301 is used for winding the pipeline to heat the pipeline. The outer peripheral surface of the heating cylinder 301 is provided with a pipe penetrating channel 302 penetrating through the arc-shaped wall of the heating cylinder 301, and the pipe penetrating channel 302 is used for allowing a pipeline to penetrate and forming anti-falling limit for the pipeline. The heating cylinder 301 is provided with a plurality of flanges 303, and the pipe penetrating channel 302 is arranged close to the flanges 303.

As shown in fig. 11 to 16, the detection assembly further includes an assembly seat, the preheating tank 250 and the blending tank 240 are assembled through the assembly seat, the assembly seat includes a first assembly body 210, two surfaces of the first assembly body 210 facing away from each other are respectively provided with a first assembly groove 211 and a second assembly groove 212, the first assembly groove 211 and the second assembly groove 212 are respectively used for setting the blending tank 240 and the preheating tank 250, and the position of the first assembly groove 211 is higher than that of the second assembly groove 212 so that the blending tank 240 is higher than that of the preheating tank 250.

The first assembly body 210 is stepped and includes a connection portion 214, a first assembly portion 216 extending upward from one side of the connection portion 214, and a second assembly portion 218 extending downward from the other side of the connection portion 214, the first assembly groove 211 is recessed in the first assembly portion 216 and the connection portion 214,

the second fitting groove 212 is recessed in the second fitting groove 212 and the connecting portion 214.

The assembly base further comprises a second assembly body 220 and a third assembly body 230, the second assembly body 220 is provided with a third assembly groove 221 and is buckled with the first assembly groove 211 to form a blending pool 240, and the third assembly body 230 is provided with a fourth assembly groove 231 and is buckled with the second assembly groove 212 to form a preheating pool 250.

As shown in fig. 5, the heating assembly includes a heating block 110 and a heating film 117 attached to a side of the heating block 110, and the heating block 110 is provided with a mounting cavity 113 for receiving the optical detection cell 120.

As shown in fig. 2 and 8, the detecting device further includes a stand 100 and a detecting component.

Wherein, the stand 100 comprises a first support arm 102 and a second support arm 104, the heating component is fixed by the first support arm 102, the pipeline heating component 300 is arranged at the side of the heating block 110 by the second support arm 104,

the detection assembly further includes a substrate 130, a laser 156, and a light receiver.

The substrate 130 is fixed to the heating block 110, the substrate 130 is provided with a notch 134 clamped and matched with the heating block 110, the light inlet channel 133, the first light outlet channel 131 and the second light outlet channel 132, the notch 134 is arranged between the light inlet channel 133 and the first light outlet channel 131 and the second light outlet channel 132, the light inlet channel 133 is aligned to the first light outlet channel 131, the axis of the second light outlet channel 132 is inclined relative to the axis of the first light outlet channel 131, the laser 156 is arranged in the light inlet channel 133, the light receiver comprises a first photodiode 141 and a second photodiode 142, the first photodiode 141 is assembled in the first light outlet channel 131, and the second photodiode 142 is assembled in the second light outlet channel 132.

The detection device that this embodiment provided heats respectively a plurality of ponds through a plurality of heating members, and the temperature of a plurality of heating members can set up the difference in order to provide the temperature demand that corresponds, can realize the rapid heating, and accurate heat preservation improves and detects the precision. The embodiment also provides a sample analyzer, which comprises the detection device.

The embodiment also provides a detection device, which comprises an optical detection cell, a first heater and a second heater, wherein the first heater is used for heating the optical detection cell; the second heater is used for heating the reagent input into the optical detection cell; wherein, the heating temperature of first heater and second heater is the differentiation setting, for example the heating temperature of second heater is higher than the heating temperature of first heater 1-7 degrees, and of course, in other test operating modes, the heating temperature of second heater also can be less than the heating temperature of first heater, and real reagent detects needs and decides. In one embodiment, the heating temperature of the optical detection cell can be set to 34-36 degrees, the heating temperature of the preheating cell and the mixing cell can be set to 40-42 degrees, the heating temperature of the diluent cell can be set to 36-38 degrees, and the heating temperature of the pipeline heating assembly can be set to 34-36 degrees.

According to the detection device provided by the invention, the optical detection pool and the reagent input into the optical detection pool are respectively heated by the at least two heaters, and the temperatures of the at least two heaters are arranged in a differentiated manner, so that the reagent can be rapidly heated, the optical detection pool can be accurately insulated, and the detection efficiency and the detection precision are improved.

The second heater includes an antibody reagent heater for heating the antibody reagent input into the optical detection cell, and since the antibody reagent is usually dispensed from a refrigerated state, heating the antibody reagent by the second heater with a relatively high heating temperature can shorten the heating time and improve the heating efficiency, wherein the antibody reagent can be heated in a pipeline (for example, by using the pipeline heating assembly 300 described below) or in the cell body (for example, the blending cell 240 described above). The second heater may comprise a hemolysis reagent heater for heating the hemolysis reagent input to the optical detection cell, and the hemolysis reagent may be heated in a tube (e.g., using the tube heating assembly 300 described below) or in a cell body (e.g., the mixing cell 240 described above). The second heater may also include a diluent heater for heating the diluent input to the optical detection cell, the diluent may be heated in a conduit (e.g., using conduit heating assembly 300 described below) or in the cell body, and the diluent heater may refer to third heater 263 in fig. 3.

The detection device further comprises a pipeline and a pool body which are directly or indirectly communicated with the optical detection pool, the pipeline is bent naturally or coiled, and the pipeline can be heated by the pipeline heating assembly 300 when coiled.

The cell body includes the mixing pond, and mixing pond and optical detection pond intercommunication, mixing pond are used for the input antibody reagent, and the second heater heats the mixing pond and then heats the antibody reagent. Or, the cell body includes the mixing pond, and mixing pond and optical detection pond are mixing and detect integrative pond, in other words, optical detection pond is used for receiving the reagent after the mixing or is used for receiving the reagent and carries out the reagent mixing in optical detection pond, and optical detection pond undertakes detection function and mixing function. The cell body still can include preheating the pond, preheats the pond and is used for inputing hemolysis reagent, preheats pond and mixing pond intercommunication, perhaps preheats pond and the integrative pond intercommunication of mixing detection.

The first heater and the second heater are heat-conducting substrates provided with heating rods or heating films, and the heat-conducting substrates are block-shaped, step-shaped (such as an assembly seat described in the fourth embodiment), cylindrical (such as a pipe heating assembly 300 described below), or box-shaped.

As shown in fig. 22, the present embodiment also includes a detection device, which includes a preheating tank 411, a blending tank 412, an optical detection tank 413, a blending pipe 414, a diluent pipe 415, a first heater 511, a second heater 512, a third heater 513, and a fourth heater 514.

Wherein, the mixing tank 412 is communicated with the preheating tank 411; the optical detection cell 413 is communicated with the blending cell 412; the preheating tank 411 and the blending tank 412 are arranged in a second heater 512, and the second heater 512 is used for heating the preheating tank 411 and the blending tank 412. The optical detection cell 413 is disposed in the first heater 511, and the first heater 511 is used for heating the optical detection cell 413, wherein the temperature of the second heater 512 can be 1-3 degrees higher than the temperature of the first heater 511 to achieve the effect of rapid heating. The blending pipeline 414 is communicated with the optical detection cell 413 and is arranged in the third heater 513, the third heater 513 is used for heating the blending pipeline 414, and the temperature of the third heater 513 can be 1-2 ℃ higher than that of the first heater 511, so that a good heat preservation effect is achieved. The diluent pipeline 415 is communicated with the blending pipeline 414, the fourth heater 514 is used for heating the diluent pipeline 415, and the temperature of the fourth heater 514 can be 1-3 ℃ higher than that of the first heater 511 so as to achieve the effect of rapid heating.

As shown in fig. 23, the present embodiment is also a detection apparatus including a preheating well 421, a kneading well 422, an optical detection well 423, a buffer well 424, a first heater 521, a second heater 522, and an antibody reagent storage 426.

The antibody reagent storage device 426 is communicated with the blending pool 422 through a pipeline and is used for inputting an antibody reagent into the blending pool 422, and the blending pool 422 is communicated with the preheating pool 421; the optical detection cell 423 is communicated with the blending cell 422; the preheating tank 421 and the blending tank 422 are arranged in the second heater 522, and the second heater 522 is used for heating the preheating tank 421 and the blending tank 422. The buffer cell 424 is communicated with the optical detection cell 423 and is jointly arranged in the first heater 521, and the temperature of the second heater 522 can be 1-3 degrees higher than that of the first heater 521 to achieve the effect of rapid heating.

As shown in fig. 24, the present embodiment also provides a detection apparatus including a preheating tank 431, a kneading detection integrated tank 430, a kneading line 434, a first heater 531, a second heater 532, and an antibody reagent tank 436.

Wherein the optical detection tank and the blending tank share the first tank body 430; the antibody reagent storage device 436 is communicated with the first tank body 430 through a pipeline and is used for inputting an antibody reagent into the first tank body 430, the preheating tank 431 is communicated with the first tank body 430 and is arranged in the first heater 531, and the first heater 531 is used for heating the preheating tank 431 and the first tank body 430. The blending pipeline 434 is communicated with the first tank body 430 and is arranged in the second heater 532, and the temperature of the second heater 532 can be 1-2 ℃ higher than that of the first heater 531 so as to achieve a better heat preservation effect.

As shown in fig. 25, the present embodiment is also a detection apparatus including a preheating bath 441, a kneading bath 442, an optical detection bath 443, a kneading line 444 (or buffer bath), a diluent line 445, a first heater 541, and a second heater 542.

Wherein, the blending tank 442 is communicated with the preheating tank 441; the optical detection cell 443 is communicated with the blending cell 442, and the blending pipeline 444 is communicated with the optical detection cell 443; the preheating tank 441, the blending tank 442, the optical detection tank 443, and the blending pipe 444 are disposed in the first heater 541, and the first heater 541 is used for heating the preheating tank 441, the blending tank 442, the optical detection tank 443, and the blending pipe 444. The diluent pipeline 445 is communicated with the blending pipeline 444, the second heater 542 is used for heating the diluent pipeline 445, and the temperature of the second heater 542 can be 1-3 degrees higher than that of the first heater 541, so that the effect of rapid heating is achieved.

As shown in fig. 26, the present embodiment is also a detection apparatus including a preheating chamber 451, a kneading chamber, an optical detection chamber, a kneading line 454, a first heater 551, and an antibody reagent chamber 456.

The optical detection pool and the blending pool share the first pool body 450, the antibody reagent pool 456 is communicated with the first pool body 450 through a pipeline and is used for inputting an antibody reagent into the first pool body 450, and the preheating pool 451, the first pool body 450 and the blending pipeline 454 (or a buffer pool) are jointly arranged in the first heater 551.

In the above embodiments, the first heater is a heat conductive substrate provided with a heating rod or a heating film, and conducts heat by direct contact or by air. The invention also provides a sample analyzer comprising the detection device of any one of the preceding embodiments.

A seventh embodiment, the present embodiment provides a detection apparatus, as shown in fig. 1 to fig. 21, the detection apparatus includes a preheating tank 250, a blending tank 240, a diluent tank 270, an optical detection tank 120, and a pipeline heating assembly 300, the preheating tank 250, the blending tank 240, the diluent tank 270, and the optical detection tank 120 are connected through a pipeline, the pipeline heating assembly 300 includes a heating barrel 301, and an outer peripheral surface of the heating barrel 301 is used for winding a pipeline to heat the pipeline.

As shown in fig. 17 to 21, a pipe penetrating channel 302 penetrating through the arc-shaped wall of the heating cylinder 301 is provided on the outer circumferential surface of the heating cylinder 301, and the pipe penetrating channel 302 is used for allowing the pipe to pass through and forming an anti-drop limit for the pipe. The tube passing channel 302 is in a straight strip shape or a bent strip shape. The tube passing channel 302 is away from the diameter of the heating cartridge 301 and close to the outer circumferential surface of the heating cartridge 301. The heating cylinder 301 is provided with a plurality of flanges 303, and the pipe penetrating channel 302 is arranged close to the flanges 303.

The detection device further comprises an assembly seat, the preheating pool 250 and the blending pool 240 are assembled through the assembly seat, the assembly seat comprises a first assembly body 210, two surfaces, away from each other, of the first assembly body 210 are respectively provided with a first assembly groove 211 and a second assembly groove 212, the first assembly groove 211 and the second assembly groove 212 are respectively used for setting the blending pool 240 and the preheating pool 250, and the position of the first assembly groove 211 is higher than that of the second assembly groove 212 so that the blending pool 240 is higher than that of the preheating pool 250.

As shown in fig. 12, the first assembly body 210 is formed in a stepped manner, and includes a connection portion 214, a first assembly portion 216 extending upward from one side of the connection portion 214, and a second assembly portion 218 extending downward from the other side of the connection portion 214, the first assembly groove 211 is recessed in the first assembly portion 216 and the connection portion 214, and the second assembly groove 212 is recessed in the second assembly groove 212 and the connection portion 214.

The detection device comprises a first heating body 261, a second heating body 262 and a third heating body 263, wherein the first heating body 261 is attached to the outer surface of the second assembling seat and used for heating the blending pool 240, the second heating body 262 is attached to the outer surface of the third assembling seat and used for heating the preheating pool 250, and the third heating body 263 is attached to the outer surface of the diluent pool 270 and used for heating the diluent pool 270. The detection device that this embodiment provided can heat and keep warm the reagent in the pipeline through adding pipeline heating element 300, can improve and detect the precision, and this embodiment still provides a sample analyzer, and this sample analyzer includes aforementioned detection device.

In an eighth embodiment, this embodiment provides a detection apparatus, as shown in fig. 27 and 28, the detection apparatus includes a heating element 410, a container 420, a fluid dynamic device 430, and a reagent pipeline 440, the reagent pipeline 440 is connected between the container 420 and the fluid dynamic device 430, at least a portion of the reagent pipeline 440 is densely wound and disposed on the heating element 410, the reagent pipeline 440 is used for conveying a reagent to the container 420 through the fluid dynamic device 430, or the fluid dynamic device 430 is used for sucking and discharging a blending reagent, and the reagent is heated by the heating element 410 during the conveying or sucking, discharging and blending process of the fluid dynamic device 430. Of course, the detection device further includes other components such as a sampling needle and a reversing valve, and the details are not described in the present application since the invention point is not related.

The hydrokinetic device 430 may be a syringe, a quantitative pump or an air pump in the analyzer, and the heating element 410 and the container 420 may be the same device or different devices.

Specifically, when the heating element 410 and the container 420 are different devices, reference may be made to fig. 27, that is, the heating element 410 is an independent heating device, and may be specially used for heating the reagent pipeline 440, and particularly, the reagent may be heated by the independent heating element 410 during the process of sucking, spitting and mixing the reagent by the hydrodynamic device 430. As shown in fig. 28, when the heat-generating body 410 and the container 420 are the same component, that is, the container 420 has a heat-conducting function due to the heat-generating body 410, and the reagent tube 440 is densely wound around the outer circumference of the container 420, thereby obtaining a heating effect.

In one embodiment, the heating element 410 is a separate heating cylinder, and the separate heating cylinder includes a winding tube base (refer to the heating cylinder 301) for winding the reagent conduit 440 and a heating element (refer to the heating rod 346) disposed in the winding tube base or attached to the outside of the reagent conduit 440. The heating element can be a heating rod inserted in the winding pipe base body, or the heating element is a heating film attached to the outer side of the pipeline.

The outer surface of the winding tube substrate is provided with a tube bundle structure, the tube bundle structure can be a tube penetrating channel (refer to the tube penetrating channel 302) or a tube clamping groove which is arranged on the surface of the winding tube substrate, the tube clamping groove is in a closed groove and is sunken on the surface of the winding tube substrate, and the tube bundle structure can be pressed and kept in the tube clamping groove through the deformation of the reagent pipeline 440.

The reagent tube 440 may be spirally wound in a cylindrical shape, or the reagent tube 440 may be spirally wound in a disc shape, or the reagent tube 440 may be wound in an S-shape, and when the reagent tube 440 is spirally wound in a disc shape or wound in an S-shape, the heating element 410 may be in a planar shape.

The container 420 may include an optical detection cell 120 and the reagent conduit 440 includes a diluent conduit for transporting diluent, the diluent conduit being disposed between the optical detection cell 120 and the hydrodynamic device 430. The container 420 may further include a blending tank, and the reagent conduit 440 includes an antibody reagent conduit for transporting an antibody reagent, the antibody reagent conduit being disposed between the blending tank and the hydrodynamic device 430. The container 420 may further comprise a pre-heat reservoir, and the reagent conduit 440 comprises a hemolysis reagent conduit for transporting a hemolysis reagent, the hemolysis reagent conduit being disposed between the pre-heat reservoir and the hydrodynamic device 430.

Referring to fig. 29, the detecting device may include a heating element 410, a container 420, a hydrodynamic device 430, a reagent tube 440, a reversing valve 450, a temperature control system 460, a waste liquid treating device 470, a reagent bottle 480, and the like.

The reagent pipeline 440 is connected between the container 420 and the fluid dynamic device 430, at least a part of the reagent pipeline 440 is wound and disposed on the heating element 410, for example, the pipeline C, D is wound and disposed on the heating element 410, the reagent pipeline 440 is used for conveying a reagent to the container 420 through the fluid dynamic device 430, the fluid dynamic device 430 is also used for sucking and spitting a blending reagent, the reagent is heated by the heating element 410 in the sucking and spitting blending process of the fluid dynamic device 430, the reagent is heated by the heating element 410 in the conveying process of the fluid dynamic device 430 to the container 420, the heating element 410 may be a heating barrel, and the temperature control system 460 may include a temperature sensor, a heating rod, a temperature control switch, and the like.

The reagent may be hemolysis reagent, antibody reagent, diluent, or mixture of two or three of them. Correspondingly, the number of the reagent bottles 480 is plural, and the reagent bottles 480 are respectively used for holding hemolysis reagent, antibody reagent, diluent and the like, the reagent bottles 480 are connected with the container 420 and the liquid power device 430 through the reversing valve 450, the number of the reversing valve 450 and the liquid power device 430 can be one or more, depending on the actual liquid path requirement, the hemolysis reagent and the antibody reagent can be heated by the heating element 410 when being transported to the container 420 in the reagent pipeline 440, the heating time is relatively short, the influence on the detection caused by the poor activity of the reagent due to long-time heating can be avoided, and simplified the structure, need not to set up corresponding preheating tank alone, the diluent can avoid relatively microthermal diluent to enter into the container 420 of relative high temperature and can reduce the temperature of container 420 through heat-generating body 410 heating when being carried to container 420 in reagent pipeline 440, can be convenient for next sample testing's quick the going on from this.

Referring to fig. 30, the detecting apparatus includes a heating element 410, a container 420, a hydrodynamic device, at least one reversing valve, and a plurality of reagent pipes, wherein at least a portion of the reagent pipes are connected between the container 420 and the hydrodynamic device and wound around the heating element 410 to form a winding section; at least part of the reagent pipeline is used for sucking the reagent through the liquid power device and the reversing valve, and the reagent enters the winding section and is heated through the heating body 410 in the reagent sucking process of the liquid power device; or at least part of the reagent pipeline is used for pushing and sucking the reagent to the container 420 through the liquid power device and the reversing valve, and the reagent enters the winding section to be heated through the heating body 410 in the process of pushing and sucking the reagent by the liquid power device.

Wherein, heat-generating body 410 is an independent heating cylinder, an independent heating cylinder is including twining a tub base and heating member, twine a tub base and be used for supplying reagent pipeline winding, the heating member sets up in twining a tub base or pastes and establishes the reagent pipeline outside, the heating member is for inserting the heating rod who locates in twining a tub base, perhaps the heating member pastes the heating film of locating the section of convoluteing periphery for the cladding formula, the surface of twining a tub base is equipped with the bundle tubular construction, the bundle tubular construction is for locating the poling passageway or the card pipe groove of twining a tub base surface, the reagent pipeline can be the teflon pipe.

In one embodiment, the reagent pipeline comprises a first reagent suction pipeline G, a first reagent pushing pipeline BF and a first public pipeline I; the reversing valve comprises a first reversing valve 1; the hydrodynamic device comprises a first hydrodynamic device 431; a first common conduit I connects the common port of the first reversing valve 1 with the first hydrodynamic device 431; one end of the first reagent suction pipeline G is connected with one branch reversing port of the first reversing valve 1, the other end of the first reagent suction pipeline G is used for connecting a first reagent bottle, such as a reagent bottle containing diluent, and the first hydrodynamic device 431 sucks reagent through the first common pipeline I, the first reversing valve 1 and the first reagent suction pipeline G; first reagent propelling movement pipeline BF is around establishing on heat-generating body 410 and dividing another switching-over mouth with first switching-over valve 1 and being connected with container 420, first liquid power device 431 is through first public pipeline I, first switching-over valve 1 and first reagent propelling movement pipeline BF push away reagent or push away inhale reagent and reach and inhale and tell the mixing effect, this reagent is heated through heat-generating body 410 after getting into the winding section, inhale reagent or push away inhale the reagent operation in the first reagent bottle next time before, there is the reagent in the operation messenger first reagent propelling movement pipeline BF of previous time, this reagent has been heated in the void time before the next operation.

In one embodiment, the reagent pipeline comprises a second reagent suction pipeline H, a second reagent pushing pipeline and a second public pipeline E; the reversing valve comprises a second reversing valve 2; the hydrokinetic device comprises a second hydrokinetic device 432; a second common conduit E connects the common port of the second reversing valve 2 with a second hydraulic power means 432; one end of the second reagent suction pipeline H is connected with one branch reversing port of the second reversing valve 2, the other end of the second reagent suction pipeline H is used for connecting a second reagent bottle, such as a reagent bottle containing a hemolytic agent, and the second liquid power device 432 sucks the reagent through the second common pipeline E, the second reversing valve 2 and the second reagent suction pipeline H; the second reagent pushing pipeline is wound on the heating body 410 and connects the other branch reversing port of the second reversing valve 2 with the container 420, the second liquid power device 432 pushes or pushes the reagent through the second common pipeline E, the second reversing valve 2 and the second reagent pushing pipeline to achieve the effect of sucking, spitting and uniformly mixing, and the reagent is heated through the heating body 410 after entering the winding section. Wherein, the second reagent pushing pipeline can be a single pipe or a plurality of pipes in the following embodiments.

In one embodiment, the reagent lines include a second reagent extraction line H, a third reagent line extraction line J, a second common line E, a third common line CD, and a fourth common line a; the reversing valves comprise a second reversing valve 2 and a third reversing valve 3; the hydrokinetic device comprises a second hydrokinetic device 432; one end of the second reagent suction pipeline H is connected with one branch reversing port of the second reversing valve 2, the other end of the second reagent suction pipeline H is used for connecting a second reagent bottle, such as a reagent bottle containing a hemolytic agent, and the second liquid power device 432 sucks the reagent through the second common pipeline E, the second reversing valve 2 and the second reagent suction pipeline H; one end of a third reagent tube suction pipeline J is connected with one branch reversing port of the third reversing valve 3, and the other end of the third reagent tube suction pipeline J is used for connecting a third reagent bottle, such as a reagent bottle containing antibody liquid; a second common conduit E connects the common port of the second reversing valve 2 with a second hydraulic power means 432; the third common pipeline CD is wound on the heating body 410 and connects the other branch reversing port of the second reversing valve 2 with the common port of the third reversing valve 3; a third common conduit CD connects the other branch port of the third diverter valve 3 with the container 420.

The second liquid power device 432 pushes or pushes the reagent through the second common pipe E, the second reversing valve 2, the third common pipe CD, the third reversing valve 3 and the fourth common pipe a to achieve the effect of sucking, spitting and mixing the reagent, the reagent is heated by the heating element 410 after entering the winding section,

the second liquid power device 432 sucks reagent through the second common pipeline E, the second reversing valve 2, the third common pipeline CD, the third reversing valve 3 and the third reagent sucking pipeline J, at this time, the reagent enters the winding section and is heated by the heating body 410, since the operation of sucking or pushing the reagent in the second reagent bottle has been previously performed, the second common line E, the third common line CD, and the fourth common line a are filled with the reagent before the next operation, wherein the conduit relatively near the end of the second hydrodynamic device 432 is primarily filled with reagent from the second reagent bottle, therefore, when the reagent in the third reagent bottle is sucked, the reagent in the second reagent bottle near the end of the second hydrodynamic device 432 and the reagent in the third reagent bottle near the end of the third reversing valve 3 are contained in the third common pipeline CD, and the two reagents can be simultaneously heated in the winding section at the gap time before the next operation. The embodiment reduces the number of structural members through pipeline multiplexing, reversing valve multiplexing and heating body multiplexing, optimizes the pipeline layout, improves the temperature control effect of the reagent, can reduce the temperature fluctuation of the container 410, and improves the detection stability. The present embodiment also provides a sample analyzer, which includes the aforementioned detection device. According to the scheme provided by the invention, the reagent is heated by the heating element 410 in the process of sucking, spitting and uniformly mixing the liquid power device 430, so that the reagent in the reagent pipeline 440 can be heated and insulated, and the detection precision is improved.

Claims

1. An optical detection cell for a blood analyzer, the optical detection cell comprising:

2. The optical detection cell according to claim 1, wherein the cell body is further provided with a liquid guiding groove, the liquid guiding groove connects the through groove and the liquid injection channel, and the liquid guiding groove is connected with the liquid injection channel in an inclined manner.

3. The optical detection cell according to claim 2, wherein the liquid guide groove is connected to a top end of the through groove.

4. The optical detection cell of claim 2, wherein the acute angle formed by the liquid guiding groove with respect to the vertical direction is less than or equal to 30 degrees.

5. The optical detection cell of claim 2, wherein the liquid guiding groove is recessed in two opposite surfaces of the cell body.

6. The optical detection cell according to claim 1, wherein the cross section of the through groove is circular hole-shaped, square hole-shaped or racetrack-shaped, the bottom side of the through groove in the longitudinal section of the through groove is horizontally or obliquely arranged, and the included angle range of the bottom side of the through groove relative to the horizontal plane when the bottom side of the through groove is obliquely arranged is less than or equal to 35 degrees.

7. The optical detection cell according to claim 1, wherein the cell body is a metal cell body, a ceramic cell body, a glass cell body or a plastic cell body, the light-transmitting plate is a glass plate or a plastic plate, and the light-transmitting plate and the cell body are fixed by adhesive bonding, laser welding or screws.

8. The optical detection cell according to claim 1, wherein the liquid injection channel is connected with liquid injection pipes, and the number of the liquid injection channel and the number of the liquid injection pipes are two and are arranged diagonally.

9. The optical detection cell of claim 1, wherein the cell body is provided with a boss, a rib, a skirt or a recessed area for positioning and assembling the light-transmitting plate.

10. The blood analyzer is characterized by comprising the optical detection pool, the blending pool and the detection assembly according to any one of claims 1 to 9, wherein the blending pool is communicated with the optical detection pool, the detection assembly is provided with a notch part for accommodating the optical detection pool, and the detection assembly further comprises a laser and a light receiver which are respectively arranged on two sides of the notch part.