CN211689066U - Fermentation cylinder spraying feed supplement device - Google Patents
Fermentation cylinder spraying feed supplement device Download PDFInfo
- Publication number
- CN211689066U CN211689066U CN201922222809.XU CN201922222809U CN211689066U CN 211689066 U CN211689066 U CN 211689066U CN 201922222809 U CN201922222809 U CN 201922222809U CN 211689066 U CN211689066 U CN 211689066U
- Authority
- CN
- China
- Prior art keywords
- pipeline
- valve
- distributor
- fermentation cylinder
- feed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000855 fermentation Methods 0.000 title claims abstract description 83
- 230000004151 fermentation Effects 0.000 title claims abstract description 83
- 239000006052 feed supplement Substances 0.000 title claims abstract description 25
- 238000005507 spraying Methods 0.000 title claims abstract description 15
- 239000007788 liquid Substances 0.000 claims abstract description 19
- 239000000463 material Substances 0.000 claims abstract description 12
- 239000007921 spray Substances 0.000 claims description 22
- 239000012528 membrane Substances 0.000 claims description 8
- 230000001502 supplementing effect Effects 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims 2
- 239000002253 acid Substances 0.000 abstract description 7
- 239000000758 substrate Substances 0.000 abstract description 5
- 238000005842 biochemical reaction Methods 0.000 abstract description 4
- 238000006243 chemical reaction Methods 0.000 abstract description 4
- 239000002699 waste material Substances 0.000 abstract description 3
- 230000035484 reaction time Effects 0.000 abstract description 2
- 239000013589 supplement Substances 0.000 abstract 1
- 239000007789 gas Substances 0.000 description 11
- 150000001413 amino acids Chemical class 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 235000011114 ammonium hydroxide Nutrition 0.000 description 2
- 238000005034 decoration Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000036632 reaction speed Effects 0.000 description 2
- NAOLWIGVYRIGTP-UHFFFAOYSA-N 1,3,5-trihydroxyanthracene-9,10-dione Chemical compound C1=CC(O)=C2C(=O)C3=CC(O)=CC(O)=C3C(=O)C2=C1 NAOLWIGVYRIGTP-UHFFFAOYSA-N 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000006353 environmental stress Effects 0.000 description 1
- 239000002921 fermentation waste Substances 0.000 description 1
- 238000009689 gas atomisation Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Images
Landscapes
- Fertilizers (AREA)
Abstract
The utility model provides a fermentation cylinder spraying feed supplement device, including first pipeline, second pipeline, third pipeline, flowmeter, first manometer, air filter, fourth pipeline, venturi, aseptic air valve, high pressure steam valve, feed supplement valve, top feed valve and bottom feed valve, put through aseptic air through putting through air filter through venturi left end, the lower part is put through feed supplement jar through feed supplement valve, the right-hand member gets into the fermentation cylinder through the distributor, aseptic air becomes through venturi velocity of flow grow, atmospheric pressure diminishes, feed liquid to be fed back dilutes and atomizes through venturi rapidly; the device adopts a mode of rapidly atomizing supplemented material liquid to high-speed gas to supplement the material to the fermentation liquid, so that the material is uniformly dispersed, the mass transfer capacity is improved, the pH gradient and the substrate concentration gradient are reduced, the biochemical reaction rate is improved, the reaction time is shortened, the generation of mixed acid is reduced, the sugar-acid conversion rate is improved, and the waste is reduced.
Description
Technical Field
The utility model belongs to the technical field of amino acid fermentation equipment and specifically relates to a fermentation cylinder spraying feed supplement device.
Background
In the existing amino acid fermentation process, in order to reduce substrate inhibition, prolong fermentation time and improve equipment utilization rate, fed-batch fermentation is mostly carried out, and ammonia water, sodium hydroxide, glucose or other nutrient substances are supplemented into a fermentation tank in time according to requirements in the fermentation process.
The recombinant Escherichia coli is widely applied to the field of amino acid fermentation as an important industrial microorganism, but the Escherichia coli has poor environmental stress resistance. Most of the current amino acid fermentation tank feed supplements are injected from the top single strand of the fermentation tank, and local ammonia water (ammonia gas) concentration is extremely high due to the limitation of mass transfer capacity in the fermentation tank (particularly a large fermentation tank), so that local pH is too high, microbial cells are burned, or local glucose concentration is too high, and other mixed acids such as acetic acid are generated. Because the mass transfer capacity of the fermentation tank is limited, the phenomenon of pH gradient or substrate concentration gradient in a fermentation culture medium is caused, so that judgment errors of engineers are often caused, the fermentation control level is seriously reduced, and the consequences of slow biochemical reaction speed, prolonged fermentation period, low saccharic acid conversion rate, serious waste and the like are caused.
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve the technical problem that a fermentation cylinder spraying feed supplement device is provided, spraying feed supplement device has overcome among the prior art fermentation cylinder transmission ability poor, and the material mixes the effect poor and the biochemical reaction speed that arouses slows down, fermentation cycle extension, many, the sugar-acid conversion rate low scheduling problem of mixed acid.
In order to solve the technical problem, the technical scheme of the utility model is that:
the utility model provides a fermentation cylinder spraying feed supplement device, includes first pipeline, second pipeline, third pipeline, flowmeter, first manometer, air filter, fourth pipeline, venturi, aseptic air valve, high pressure steam valve, feed supplement valve, top feed valve and bottom feed valve, third pipeline left end is through aseptic air valve and first pipeline intercommunication, through high pressure steam valve and second pipeline intercommunication, and the right-hand member is through air filter and venturi intercommunication, the venturi lower part is through feed supplement valve and fourth pipeline intercommunication, and the venturi right-hand member divide into two pipelines respectively through top feed valve and bottom feed valve entering fermentation cylinder behind the tee bend, the top distributor left end of establishing in the fermentation cylinder links to each other with the top feed valve, the bottom distributor left end of establishing in the fermentation cylinder links to each other with the bottom feed valve.
The left end of the venturi tube is communicated with sterile air through an air filter membrane, the lower part of the venturi tube is communicated with a material supplementing tank through a material supplementing valve, the right end of the venturi tube enters a fermentation tank through a distributor, the flow velocity of the sterile air is increased through the venturi tube, the air pressure is reduced, and the material to be supplemented is rapidly diluted and atomized through the venturi tube.
Preferably, above-mentioned fermentation cylinder spraying feed supplement device, the internal jar of a body agitator that is equipped with of jar of fermentation cylinder, the fermentation cylinder still includes support frame, second manometer, fifth pipeline, top distributor, bottom distributor and exhaust valve, and wherein, second manometer and fifth pipeline are installed on the external top of jar of fermentation cylinder, are provided with the exhaust valve on the fifth pipeline, the top distributor passes through the support frame and hangs in the inside top of fermentation cylinder with jar body welded fastening, and the bottom distributor passes through the support frame and jar body welded fastening, and the bottom of bottom distributor in the fermentation cylinder inside is lifted to the support frame.
Preferably, in the spray feeding device for the fermentation tank, the number of the support frames is four.
Preferably, in the spray feeding device for the fermentation tank, the top distributor and the bottom distributor are both annular round pipes, and the lower opening is communicated with a plurality of nozzles, so that feed liquid can be further dispersed and materialized and enters the fermentation tank in a spray mode.
Preferably, in the spray feeding device for the fermentation tank, the first pipeline, the second pipeline and the fourth pipeline are respectively connected with sterile air, high-pressure steam and a feeding bottle/tank.
Preferably, in the spray feeding device for the fermentation tank, the upper part of the third pipeline is respectively connected with a flowmeter and a first pressure gauge.
Has the advantages that:
according to the fermentation tank spraying and feeding device, feeding liquid to be fed is atomized by the venturi tube and is primarily dispersed into small liquid drops, then secondary atomization is carried out through the air distributor at the bottom of the fermentation tank or the distributor nozzle at the top of the fermentation tank, and the spraying enters the fermentation liquid, so that the uniform feeding of the fermentation liquid is completed; the method for supplementing the fermentation tank by adopting the high-speed gas atomization feed liquid to be supplemented can effectively overcome the defects of local pH gradient and substrate concentration gradient caused by poor mass transfer performance and poor material mixing effect; the feed liquid to be supplemented can be effectively dispersed and added after being atomized and sprayed into the fermentation tank, so that the mass transfer capacity of the fermentation tank is improved, the pH gradient and the substrate concentration gradient are reduced, the biochemical reaction rate is improved, the reaction time is shortened, the generation of mixed acid is reduced, the sugar-acid conversion rate is improved, and the waste is reduced.
Drawings
FIG. 1 is a schematic structural diagram of a spray feeding device of a fermentation tank of the present invention;
FIG. 2 is a schematic view taken along line A-A of FIG. 1;
FIG. 3 is a schematic view taken along line B-B of FIG. 1;
FIG. 4 is a schematic of top sparger spray feed;
FIG. 5 is a schematic of the top sparger feed distribution.
In the figure, 1, a first pipeline, 2, a second pipeline, 3, a third pipeline, 4, a flow meter, 5, a first pressure gauge, 6, an air filter membrane, 7, a fourth pipeline, 8, a venturi tube, 9, a support frame, 10, a second pressure gauge, 11, a fifth pipeline, 12, a top distributor, 13, a spray head, 14, a bottom distributor, K1. sterile air valves, K2. high-pressure steam valves, K3. feeding valves, K4. top feeding valves, K5. bottom feeding valves and K6. tail gas valves are arranged.
Detailed Description
Example 1
As shown in the figure 1-3, the fermenter spray feeding device comprises a first pipeline 1, a second pipeline 2, a third pipeline 3, a flow meter 4, a first pressure gauge 5, an air filter membrane 6, a fourth pipeline 7, a Venturi tube 8, a sterile air valve K1, a high-pressure steam valve K2, a feeding valve K3, a top feeding valve K4 and a bottom feeding valve K5, the left end of the third pipeline is communicated with the first pipeline through a sterile air valve and is communicated with the second pipeline through a high-pressure steam valve, the right end of the third pipeline is communicated with the Venturi tube through an air filter membrane, the lower part of the Venturi tube is communicated with a fourth pipeline through a feeding valve, the right end of the Venturi tube is divided into two pipelines after passing through a tee joint, the two pipelines respectively enter a fermentation tank through a top feeding valve and a bottom feeding valve, the left end of a top distributor arranged in the fermentation tank is connected with a top feeding valve, and the left end of a bottom distributor arranged in the fermentation tank is connected with a bottom feeding valve; the first pipeline, the second pipeline and the fourth pipeline are respectively communicated with sterile air, high-pressure steam and a material supplementing bottle/tank; the upper part of the third pipeline is respectively communicated with a flowmeter and a first pressure gauge; the venturi left end is through switch-on air filter switch-on sterile air, and the lower part is through feed supplement valve switch-on feed supplement jar, right-hand member get into the fermentation cylinder through the distributor, and sterile air is through venturi velocity of flow grow, atmospheric pressure diminish, and the feed supplement liquid is diluted and is atomized through venturi rapidly.
The internal agitator that is equipped with of jar of fermentation cylinder, the fermentation cylinder still includes four support frames 9, second manometer 10, fifth pipeline 11, top distributor 12, bottom distributor 14 and tail gas valve K6, and wherein, second manometer and fifth pipeline are installed on the external top of jar of fermentation cylinder, are provided with the tail gas valve on the fifth pipeline, the top distributor passes through support frame and jar body welded fastening and hangs in the inside top of fermentation cylinder, and the bottom distributor passes through support frame and jar body welded fastening, and the bottom distributor is lifted to the support frame in the inside bottom of fermentation cylinder, top distributor and bottom distributor are the annular pipe, and a plurality of shower nozzles 13 are put through to the lower part trompil, can make feed liquid further dispersion and materialization to spray mode gets into the fermentation cylinder.
In the spray feeding device for the fermentation tank, the left end of a third pipeline 3 is communicated with a first pipeline 1 through a sterile air valve K1, and the first pipeline 1 is a sterile air inlet; is communicated with a second pipeline 2 through a high-pressure steam valve K2, and the second pipeline 2 is a high-pressure steam inlet used for sterilizing the fermentation tank; the right end is communicated with a Venturi tube 8 through an air filter membrane 6. The lower part of the venturi 8 is communicated with a fourth pipeline 7 through a feed valve K3, the fourth pipeline 7 is an inlet of feed liquid to be supplemented, and the feed liquid is atomized by high-speed sterile air in the venturi 8; the right end of the three-way pipe is divided into two pipelines which respectively enter the fermentation tank through a top feeding valve K4 and a bottom feeding valve K5. The left end of the top distributor 12 is connected with a top feed valve K4, and the primarily atomized supplemented feed liquid can enter the top distributor 12 through the top feed valve K4, and is secondarily atomized through the spray head 13 and sprayed into the fermentation tank. Or the fermentation gas enters the bottom distributor 14 through a bottom feeding valve K5, is secondarily atomized by a spray head and sprayed into the fermentation tank, the fermentation waste gas is discharged through a fifth pipeline 11, and a tail gas valve K6 can be used for adjusting the tank pressure.
As shown in fig. 4-5, the arrows indicate the flow direction of the additional feed liquid, which moves forward along the pipeline under the action of gas pressure in the top distributor 12 on the one hand, and is sprayed into a mist form through the spray nozzles 13 into the fermentation broth on the other hand.
Example 2
Sterilizing a fermentation tank spraying device: the sterile air valve K1 and the feed supplement valve K3 are opened, the high-pressure steam valve K2, the top feeding valve K4 and the bottom feeding valve K5 are opened, high-pressure steam sterilizes the third pipeline, the air filter membrane 6, the Venturi tube 8, the top feeding valve K4, the bottom feeding valve K5, the top distributor 12, the bottom distributor 14, the spray head 13, the fermentation tank body, the fifth pipeline 11, the tail gas valve K6 and the culture medium from the second pipeline 2, the indication of the first pressure gauge and the indication of the second pressure gauge are monitored in the sterilization process, and the opening and closing of the valves are controlled.
Example 3
Ventilating a fermentation tank spraying device: the high-pressure steam valve K2, the feed supplement valve K3 and the top feeding valve K4 are closed, the sterile air valve 1, the bottom feeding valve K5 and the tail gas valve K6 are opened, the fermentation provides sterile air, the pressure gauge and the flow meter are observed, and the opening and closing degree of each valve is adjusted.
Example 4
Feeding a fermentation tank spraying device: the high-pressure steam valve K2 is closed, the aseptic air valve 1, the feed supplement valve K3, the top feed valve K4 and the bottom feed valve K5 are opened, the feed supplement liquid enters the Venturi tube 8 through the feed supplement valve and is primarily atomized by high-speed aseptic air, and the feed supplement liquid can enter the distributor through the top feed valve K4 and the bottom feed valve K5 independently or simultaneously at the top or the bottom, is secondarily atomized through the spray head 13 and is sprayed into the fermentation tank for feed supplement. And (4) discharging fermentation tail gas through a fifth pipeline and a tail gas valve K6, observing a pressure gauge and a flowmeter, and adjusting the opening and closing degree of each valve.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (6)
1. The utility model provides a fermentation cylinder spraying feed supplement device which characterized in that: including first pipeline, second pipeline, third pipeline, flowmeter, first manometer, filtration membrane, fourth pipeline, venturi, aseptic air valve, high-pressure steam valve, benefit material valve, top feed valve and bottom feed valve, the third pipeline left end is through aseptic air valve and first pipeline intercommunication, through high-pressure steam valve and second pipeline intercommunication, and the right-hand member is through filtration membrane and venturi intercommunication, the venturi lower part is through benefit material valve and fourth pipeline intercommunication, and the venturi right-hand member divide into two pipelines respectively through top feed valve and bottom feed valve entering fermentation cylinder behind the tee bend, the top distributor left end of establishing in the fermentation cylinder links to each other with the top feed valve, the bottom distributor left end of establishing in the fermentation cylinder links to each other with the bottom feed valve.
2. The fermenter spray feeder of claim 1, wherein: the internal agitator that is equipped with of jar of fermentation cylinder, the fermentation cylinder still includes support frame, second manometer, fifth pipeline, top distributor, bottom distributor and exhaust valve, and wherein, second manometer and fifth pipeline are installed on the external top of jar of fermentation cylinder, are provided with the exhaust valve on the fifth pipeline, the top distributor passes through the support frame and hangs in the inside top of fermentation cylinder with jar body welded fastening, and the bottom distributor passes through the support frame and jar body welded fastening, and the bottom distributor is lifted to the support frame in the inside bottom of fermentation cylinder.
3. The fermenter spray feeder apparatus of claim 2, wherein: the number of the support frames is four.
4. The fermenter spray feeder of claim 1, wherein: the top distributor and the bottom distributor are both annular round pipes, the lower part of the top distributor is provided with a hole communicated with a plurality of spray heads, so that the feed liquid can be further dispersed and materialized and enters the fermentation tank in a spraying mode.
5. The fermenter spray feeder of claim 1, wherein: and the first pipeline, the second pipeline and the fourth pipeline are respectively communicated with sterile air, high-pressure steam and a material supplementing bottle/tank.
6. The fermenter spray feeder of claim 1, wherein: and the upper part of the third pipeline is respectively communicated with a flowmeter and a first pressure gauge.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922222809.XU CN211689066U (en) | 2019-12-12 | 2019-12-12 | Fermentation cylinder spraying feed supplement device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922222809.XU CN211689066U (en) | 2019-12-12 | 2019-12-12 | Fermentation cylinder spraying feed supplement device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211689066U true CN211689066U (en) | 2020-10-16 |
Family
ID=72790895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201922222809.XU Expired - Fee Related CN211689066U (en) | 2019-12-12 | 2019-12-12 | Fermentation cylinder spraying feed supplement device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN211689066U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112592810A (en) * | 2020-12-29 | 2021-04-02 | 大同同星抗生素有限责任公司 | Feed supplement unloader in terramycin production process |
| CN114350480A (en) * | 2022-01-12 | 2022-04-15 | 万华化学(四川)有限公司 | Double-circulation bubbling fermentation tank and method for preparing lactic acid through fermentation |
-
2019
- 2019-12-12 CN CN201922222809.XU patent/CN211689066U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112592810A (en) * | 2020-12-29 | 2021-04-02 | 大同同星抗生素有限责任公司 | Feed supplement unloader in terramycin production process |
| CN114350480A (en) * | 2022-01-12 | 2022-04-15 | 万华化学(四川)有限公司 | Double-circulation bubbling fermentation tank and method for preparing lactic acid through fermentation |
| CN114350480B (en) * | 2022-01-12 | 2023-12-19 | 万华化学(四川)有限公司 | Double-circulation bubbling fermentation tank and method for preparing lactic acid by fermentation |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN211689066U (en) | Fermentation cylinder spraying feed supplement device | |
| CN103224882B (en) | Disposable wave type bioreactor with aerating apparatus | |
| CN110656043A (en) | Microbial fermentation tank for producing liquid feed additive | |
| CN215667358U (en) | Movable biological algae removal device | |
| CN202007224U (en) | Marine microbial enzyme fermentation dual gas circulation device | |
| CN103103223A (en) | Method for continuous cycle fermentation production of citric acid | |
| CN107557299A (en) | A kind of liquid atomization system for cell culture | |
| CN203855585U (en) | Bed flow type fermentation tank for gamma-polyglutamic acid | |
| CN104382208B (en) | In a kind of solid fermentation, adverse current connects bacterium device and connects bacterium method | |
| CN201506790U (en) | Fermentation tank | |
| CN202157063U (en) | Material filling device for fermenter | |
| CN205590707U (en) | Fermentation cylinder cooling back installation | |
| CN209816134U (en) | Fermentation cylinder feed supplement device | |
| CN208414406U (en) | A kind of bioreactor | |
| CN113354234A (en) | Organic waste fermenting device for animal husbandry breeding | |
| CN202968544U (en) | Continuous fermentation propagation device for reducing contamination probability | |
| CN103224872A (en) | Fermentation tank for improving tylosin production level | |
| CN209178397U (en) | A kind of seed can system expanding culture for amino acids production strain | |
| CN203530303U (en) | Series-parallel distribution system with valve group connecting mechanism | |
| CN215209391U (en) | Reinforced dissolved oxygen fermentation tank system | |
| CN208762498U (en) | A kind of material distribution device for two groups of aerobic fermentation tanks | |
| CN220413399U (en) | Novel fermentation cylinder material feed supplement device | |
| CN110479081A (en) | A kind of constraint formula bioreactor original position sulfur removal technology and its equipment | |
| CN107937452A (en) | A kind of fermentation manufacturing technique of L tryptophans | |
| CN217757480U (en) | Total pipe type seed moving device for fermentation tank |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20201016 |