CN211675903U - Orthogonal electrode circuit for irreversible electroporation ablation in esophagus - Google Patents
Orthogonal electrode circuit for irreversible electroporation ablation in esophagus Download PDFInfo
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- CN211675903U CN211675903U CN201922422129.2U CN201922422129U CN211675903U CN 211675903 U CN211675903 U CN 211675903U CN 201922422129 U CN201922422129 U CN 201922422129U CN 211675903 U CN211675903 U CN 211675903U
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- marx
- power supply
- main circuit
- irreversible electroporation
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Abstract
The utility model provides an orthogonal electrode circuit for eating intraductal irreversible electroporation melts, including positive DC power supply, burden DC power supply, FPGA the control unit, Marx main circuit and load, Marx main circuit is connected respectively to positive DC power supply and burden DC power supply, and FPGA the control unit is connected respectively to burden DC power supply, Marx main circuit and load, and Marx main circuit connection load, the utility model relates to a rationally, convenient to use makes the cell distribute evenly in organizing through the electric field energy, makes the cell melt thoroughly, and the treatment is stable, has fine application prospect.
Description
Technical Field
The utility model relates to the field of medical equipment, concretely relates to orthogonal electrode circuit that is used for irreversible electroporation to melt in esophagus.
Background
In recent years, the application of pulsed electric field in biomedical field has become a focus of research of scientists, wherein irreversible electroporation has been clinically applied as a novel non-thermal tumor ablation method and achieves better therapeutic effect. Irreversible electroporation has distinct advantages over traditional tumor treatment modalities: the method is rapid, controllable, visible, selective and non-thermal, and can be used for treating tumors of important organs and tissues adjacent to blood vessels, nerves and the like. Therefore, the method has important significance for developing research and clinical promotion of irreversible electroporation technology to the treatment of tumors and guarantee of life health of people.
However, clinical application and research show that the technology for irreversible electroporation ablation of tumors still has some difficulties and needs to be broken through. Firstly, as biological tissues contain various cells and have anisotropic characteristics, the electric field is distributed unevenly in the tissues and has larger difference with an ideal electric field simulation calculation result, so that certain residue exists when the pulsed electric field ablates the tumor, and the tumor relapse is caused; secondly, due to the stimulation of the pulse electric field, muscles and nerves can cause action potentials, thereby causing muscle contraction phenomena, increasing the pain of patients in clinical treatment, and easily causing displacement of the electrode needle, resulting in that the ablation region cannot be precisely controlled.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the defects and providing an orthogonal electrode circuit for irreversible electroporation ablation in esophagus.
The utility model aims at realizing through the following technical scheme:
the orthogonal electrode circuit for the irreversible electroporation ablation in the esophagus comprises a positive direct-current power supply, a negative direct-current power supply, an FPGA control unit, a Marx main circuit and a load, wherein the positive direct-current power supply and the negative direct-current power supply are respectively connected with the Marx main circuit, the negative direct-current power supply, the Marx main circuit and the load are respectively connected with the FPGA control unit, and the Marx main circuit is connected with the load.
The Marx main circuit comprises N units, and each unit comprises an energy storage capacitor, a diode and two switches.
The FPGA control unit comprises an EP2C35F672C6N chip.
Two switches in the Marx main circuit are MOSFET switches.
The utility model discloses following profitable effect has:
the utility model relates to a rationally, convenient to use makes the cell pass through the electric field can distribute evenly in the tissue, makes the cell melt thoroughly, and the treatment is stable, has fine application prospect.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention;
fig. 2 is a circuit diagram of the Marx main circuit of the present invention.
Detailed Description
The invention will be further described with reference to the accompanying drawings:
as shown in fig. 1 and 2, the orthogonal electrode circuit for the irreversible electroporation ablation in the esophagus comprises a positive direct-current power supply 1, a negative direct-current power supply 2, an FPGA control unit 3, a Marx main circuit 4 and a load 5, wherein the positive direct-current power supply 1 and the negative direct-current power supply 2 are respectively connected with the Marx main circuit 4, the negative direct-current power supply 2, the Marx main circuit 4 and the load 5 are respectively connected with the FPGA control unit 3, and the Marx main circuit 4 is connected with the load 5.
The Marx main circuit comprises N units, and each unit comprises an energy storage capacitor, a diode and two switches.
The FPGA control unit comprises an EP2C35F672C6N chip.
Two switches in the Marx main circuit are MOSFET switches.
The working principle is as follows: the FPGA control unit controls the direct current power supply with positive and negative polarities to charge the energy storage capacitor in the bipolar Marx main circuit, and when the charging voltage reaches a preset value, the FPGA control unit sends a synchronous trigger signal to control the solid-state switch to be switched on and off, so that the ends with different polarities of the energy storage capacitor are connected in series to discharge, and bipolar pulses are output on a load. The operator can freely set the output parameters and polarity conversion of the pulse through the user interface. In addition, the FPGA control unit also realizes the output protection and intelligent regulation and control of the generator by receiving the pulse discharge voltage and current signals detected by the load side voltage and current sensor, acquiring and processing the signals and then feeding back and controlling the output pulse amplitude.
High-frequency bipolar pulse generator Marx main circuit: the two direct current power supplies are positioned at the front end of the circuit and charge the energy storage capacitors in each module in the circuit in parallel through the charging current-limiting resistor, the isolation inductor and the diode. Each stage of the bipolar Marx circuit comprises an energy storage capacitor, a diode and two switches. The charging voltage of the capacitor of the odd-level module is-VDC, and the charged voltage of the capacitor of the even-level module is + VDC. By controlling the on-off of the switch, the different polarity ends of the capacitor can be connected in series to discharge, so that pulses with positive and negative polarities are output on the load.
Claims (4)
1. The utility model provides an orthogonal electrode circuit for esophagus irreversible electroporation is ablated, includes positive DC power supply, burden DC power supply, FPGA the control unit, Marx main circuit and load, its characterized in that: the positive direct-current power supply and the negative direct-current power supply are respectively connected with the Marx main circuit, the negative direct-current power supply, the Marx main circuit and the load are respectively connected with the FPGA control unit, and the Marx main circuit is connected with the load.
2. The orthogonal electrode circuit for esophageal irreversible electroporation ablation as claimed in claim 1, wherein: the Marx main circuit comprises N units, and each unit comprises an energy storage capacitor, a diode and two switches.
3. The orthogonal electrode circuit for esophageal irreversible electroporation ablation as claimed in claim 1, wherein: the FPGA control unit comprises an EP2C35F672C6N chip.
4. The orthogonal electrode circuit for esophageal irreversible electroporation ablation as claimed in claim 2, wherein: and two switches in the Marx main circuit are MOSFET switches.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922422129.2U CN211675903U (en) | 2019-12-30 | 2019-12-30 | Orthogonal electrode circuit for irreversible electroporation ablation in esophagus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922422129.2U CN211675903U (en) | 2019-12-30 | 2019-12-30 | Orthogonal electrode circuit for irreversible electroporation ablation in esophagus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211675903U true CN211675903U (en) | 2020-10-16 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201922422129.2U Expired - Fee Related CN211675903U (en) | 2019-12-30 | 2019-12-30 | Orthogonal electrode circuit for irreversible electroporation ablation in esophagus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN211675903U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2022176203A1 (en) * | 2021-02-22 | 2022-08-25 |
-
2019
- 2019-12-30 CN CN201922422129.2U patent/CN211675903U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2022176203A1 (en) * | 2021-02-22 | 2022-08-25 | ||
| WO2022176203A1 (en) * | 2021-02-22 | 2022-08-25 | 日本ライフライン株式会社 | Power-supply device and ablation system |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20201016 Termination date: 20211230 |