CN211453076U - Biological sample chromosome dropping device - Google Patents

Biological sample chromosome dropping device Download PDF

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Publication number
CN211453076U
CN211453076U CN201922304103.8U CN201922304103U CN211453076U CN 211453076 U CN211453076 U CN 211453076U CN 201922304103 U CN201922304103 U CN 201922304103U CN 211453076 U CN211453076 U CN 211453076U
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CN
China
Prior art keywords
bottom plate
chromosome
support
fixed
rear side
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201922304103.8U
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Chinese (zh)
Inventor
薛睿
王晨
郑玲
明东风
王玉海
袁红梅
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Zaozhuang University
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Zaozhuang University
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Publication date
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Priority to CN201922304103.8U priority Critical patent/CN211453076U/en
Application granted granted Critical
Publication of CN211453076U publication Critical patent/CN211453076U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model relates to a biological sample chromosome drips piece device, including bottom side bottom plate, rear side fan, water storage box, humidifier, front side fan, electric heater unit, drip piece operation panel, door-shaped support, slide glass groove, support track. The utility model discloses can accurately heat the humidification to and adjust the height of dropping the piece, can control the environmental factor of chromosome dispersion in-process accurately, improve the success rate of chromosome metaphase dispersion phase preparation, and control the single variable in different batches of experimentation, improve different batches of comparability, ensure the accuracy and the repeatability of experiment, equipment easy operation in addition, the sexual valence relative altitude should use widely.

Description

Biological sample chromosome dropping device
Technical Field
The utility model relates to a biological detection field especially relates to a biological sample chromosome dropping device.
Background
With the progress of modern science and technology, biological detection technology is also rapidly developed, and metaphase chromosome mounting with stable combination and good division is obtained in the process of setting cytogenetic specimen mounting aiming at karyotype analysis, which is an important technical link for analyzing cell chromosome karyotype by utilizing in situ hybridization.
Chromosome dispersion is affected by many factors such as the height of the drop, the temperature and humidity of the small environment in which the drop is spread, and the like. The degree of chromosome dispersion is critical when dropping. Chromosome dispersion is insufficient due to uncontrollable height of the dropping sheet and unbalanced temperature and humidity in the dropping sheet box, so that the chromosomes are folded or interwoven; and chromosome drift is generated when the chromosomes are excessively dispersed, and the conditions seriously reduce the quality of chromosome preparation, and are not favorable for later-stage observation photographing and karyotype analysis. Therefore, the chromosome dispersion quality is improved by controlling the height of the dropping pieces and optimizing the temperature and humidity of the small environment of the dropping pieces, experimental errors are reduced, the chromosome production of different batches keeps the same dispersion effect, the comparability of the batch production is improved, and the later-stage observation photographing and karyotype analysis are facilitated.
The chromosome scatterometer for slide production in the market at present can only realize heating and humidifying or only achieve the requirement of controlling the height of the slide drop to a limited degree, and the minienvironment of the slide drop equipment is not optimized aiming at the characteristics of in-situ hybridization karyotype analysis, so that chromosome scattered specimens with better quality are difficult to prepare.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a biological sample chromosome drips piece device to solve above-mentioned technical problem, for realizing above-mentioned purpose the utility model discloses a following technical scheme:
a biological sample chromosome dripping device comprises a bottom side bottom plate, a rear side fan, a water storage box, a humidifier, a front side fan, an electric heating device, a dripping operation table, a door-shaped support, a glass slide groove and support rails, wherein the rear side bottom plate is arranged on the top side of the rear end of the bottom side bottom plate, the bottom side bottom plate and the rear side bottom plate are integrally formed, the water storage box is arranged at the rear end of the right side of the bottom side bottom plate, the rear side fan is fixed on the top surface of the water storage box, the humidifier is fixed on the front side surface of the water storage box, the humidifier is fixed on the right side of the top surface of the bottom side bottom plate, the front side fan is fixed at the front end of the left side of the top surface of the bottom side bottom plate, the electric heating device is fixed at the rear end of the left side of the bottom side bottom plate, the rear side surface of the electric heating device is tightly attached to, the orbital rear end top surface of support is equipped with door type support, the top of door type support is connected with a set of horizontally and drips the piece operation panel, be provided with a plurality of groups slide glass groove between two sets of support tracks, a plurality of groups slide glass groove level just set up side by side at the orbital top surface of two sets of support.
On the basis of the technical scheme, a plurality of groups of dripping sheet holes are formed in the dripping sheet operation table.
On the basis of the technical scheme, the door-shaped support is connected with the support rail through a hinge.
Compared with the prior art, the utility model has the advantages of it is following: the utility model discloses can accurately heat the humidification to adjust the height of dropping the piece in a flexible way, can control the environmental factor of chromosome dispersion in-process accurately, improved the success rate of chromosome metaphase dispersion preparation, also controlled the single variable in different batches of experimentation, improved different batches of comparability, ensured the accuracy and the repeatability of experiment, equipment operation is simple in addition, and the sexual valence relative altitude is suitable for using widely.
Drawings
Fig. 1 is a general appearance state diagram of the present invention.
Fig. 2 is a schematic top plan view of the present invention.
In the figure: the device comprises a bottom side bottom plate 1, a rear side bottom plate 2, a rear side fan 3, a water storage box 4, a humidifier 5, a front side fan 6, an electric heating device 7, a dripping sheet operation table 8, a door-shaped support 9, a glass slide groove 10, a support rail 11, a dripping sheet hole 12 and a hinge 13.
Detailed Description
The invention will be described in further detail with reference to the accompanying drawings and specific embodiments.
A biological sample chromosome dripping device comprises a bottom side bottom plate 1, a rear side bottom plate 2, a rear side fan 3, a water storage box 4, a humidifier 5, a front side fan 6, an electric heating device 7, a dripping operation table 8, a door-shaped support 9, a glass slide groove 10 and a support rail 11, wherein the rear side bottom plate 2 is arranged on the top side of the rear end of the bottom side bottom plate 1, the bottom side bottom plate 1 and the rear side bottom plate 2 are integrally formed, the water storage box 4 is arranged at the rear end of the right side of the bottom side bottom plate 1, the rear side fan 3 is fixed on the top surface of the water storage box 4, the humidifier 5 is fixed on the front side surface of the water storage box 4, the humidifier 5 is fixed on the right side of the top surface of the bottom side bottom plate 1, the front side fan 6 is fixed at the front end of the left side of the top surface of the bottom side bottom plate 1, the electric heating device 7 is fixed at the rear end of the left side of the top, the support tracks 11 are provided with two groups, the two groups of support tracks 11 are parallelly and parallelly fixed at the center of the top surface of the bottom plate 1, a door-shaped support 9 is arranged on the top surface of the rear end of each support track 11, the top section of each door-shaped support 9 is connected with a group of horizontal drip operation tables 8, a plurality of groups of glass slide grooves 10 are arranged between the two groups of support tracks 11, and the groups of glass slide grooves 10 are horizontally arranged on the top surfaces of the two groups of support tracks 11 in parallel.
The dripping operation table 8 is provided with a plurality of groups of dripping holes 12.
The door-shaped carrier 9 is connected to the carrier rail 11 by means of a hinge 13.
The utility model discloses the theory of operation: experiments have found that the optimum temperature, humidity and height in the dripping experiment are explored. The best data provided by this patent are 30 °, 45% and 8 cm. Before the experiment begins, whether inspection temperature humidity meets the requirements to adjust the height of door type support, place the slide glass on the slide glass support of miniature operation panel, inhale 10 microliters's pipettors with the cell suspension that prepares, carry out the drip piece along the drip piece hole, after the drip piece is ended, cover the lid, make the slide dry under the suitable condition, drying time generally is 10~20 minutes, the utility model discloses preferred is 15 minutes. An experimenter can observe the drying degree of the slide through the observation window, and after the slide is completely dried, the experimenter takes out the slide for subsequent microscopic observation.
The foregoing is a preferred embodiment of the present invention, and for those skilled in the art to understand the teaching of the present invention, the changes, modifications, replacements and variations to the embodiments will still fall within the protection scope of the present invention without departing from the principle and spirit of the present invention.

Claims (3)

1. A biological sample chromosome dripping device is characterized by comprising a bottom side bottom plate (1), a rear side bottom plate (2), a rear side fan (3), a water storage box (4), a humidifier (5), a front side fan (6), an electric heating device (7), a dripping operation table (8), a door-shaped support (9), a glass slide groove (10) and a support rail (11), wherein the rear side bottom plate (2) is arranged on the top side of the rear end of the bottom side bottom plate (1), the bottom side bottom plate (1) and the rear side bottom plate (2) are integrally formed, the water storage box (4) is arranged at the rear end of the right side of the bottom side bottom plate (1), the rear side fan (3) is fixed on the top surface of the water storage box (4), the humidifier (5) is fixed on the front side surface of the water storage box (4), the humidifier (5) is fixed on the right side of the top surface of the bottom side bottom plate (1), the front side fan (6) is fixed on the front end of, the glass slide plate rack is characterized in that the electric heating device (7) is fixed at the rear end of the left side of the top surface of the bottom side base plate (1), the rear side face of the electric heating device (7) is tightly attached to the left end of the rear side base plate (2), the support rails (11) are provided with two sets, the two sets of support rails (11) are parallelly and parallelly fixed at the center of the top surface of the bottom side base plate (1), the top face of the rear end of the support rails (11) is provided with a door-shaped support (9), the top section of the door-shaped support (9) is connected with a set of horizontal slide dropping operation table (8), a plurality of sets of slide grooves (10) are arranged between the two sets of support rails (11), and the plurality of sets of slide grooves (10) are horizontally and parallelly arranged on.
2. The chromosome plating device for biological samples according to claim 1, wherein the plating operating platform (8) is provided with a plurality of sets of plating holes (12).
3. The chromosome plating device for biological samples according to claim 1, wherein the gantry-type support (9) is connected to the support rail (11) by a hinge (13).
CN201922304103.8U 2019-12-20 2019-12-20 Biological sample chromosome dropping device Expired - Fee Related CN211453076U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201922304103.8U CN211453076U (en) 2019-12-20 2019-12-20 Biological sample chromosome dropping device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201922304103.8U CN211453076U (en) 2019-12-20 2019-12-20 Biological sample chromosome dropping device

Publications (1)

Publication Number Publication Date
CN211453076U true CN211453076U (en) 2020-09-08

Family

ID=72299081

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201922304103.8U Expired - Fee Related CN211453076U (en) 2019-12-20 2019-12-20 Biological sample chromosome dropping device

Country Status (1)

Country Link
CN (1) CN211453076U (en)

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20200908

Termination date: 20211220

CF01 Termination of patent right due to non-payment of annual fee