CN211426520U

CN211426520U - Combined measles and rubella detection card

Info

Publication number: CN211426520U
Application number: CN201922174144.XU
Authority: CN
Inventors: 刘纱; 李琳; 徐颖
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-12-08
Filing date: 2019-12-08
Publication date: 2020-09-04
Anticipated expiration: 2029-12-08

Abstract

The utility model provides a measles rubella joint detection card includes: the kit comprises a base plate, a cover plate, sample adding cotton, a measles detection strip, a rubella detection strip, a sample adding window, a detection window, an ID area, a result interpretation area, a sample pad, a colloidal gold combination pad, a chromatographic membrane 1, a water absorption pad 1, a chromatographic membrane 2, a water absorption pad 2, an 'M' character, a 'V' character 1, an 'R' character and a 'V' character 2; the measles virus and the rubella virus can be simultaneously detected by one-time sample adding, so that the operation and detection steps are reduced; secondly, an M character and an R character which coat the goat anti-mouse IgG polyclonal antibody are arranged on the chromatographic membrane, so that whether the test paper strips are qualified or not is easy to observe, and the test items of the two test paper strips are easy to distinguish; and thirdly, the detection result is easy to interpret, the confusion of the M character, the R character and the V character can be avoided, the observation is clearer, and the misreading caused by the interference of blood can be avoided.

Description

Combined measles and rubella detection card

Technical Field

The utility model relates to an infectious disease detection reagent especially relates to a measles rubella joint detection card.

Background

Both measles and rubella are common infectious diseases of eruptive type in children, and symptoms of both are similar, so that the measles and rubella are often difficult to distinguish and diagnose clinically from other eruptive diseases such as Zika and dengue fever.

The main symptoms of measles and measles include fever and upper respiratory tract discomfort, generally with fever of moderate degree, sudden hyperpyrexia with convulsion, and rash often after fever. At present, the rubella and measles of children are diagnosed mainly by separating virus and detecting virus nucleic acid, and hospitals with insufficient conditions or by adopting an ELISA method to detect virus antibodies. However, these tests usually require large-scale instruments, high-level testing personnel, and high testing cost, and in particular, the above measures all require testing time close to 1d, which is not favorable for controlling and preventing infectious diseases. Therefore, a rapid, effective and accurate detection means for measles and rubella is needed.

Disclosure of Invention

In view of the above shortcoming of prior art, the utility model aims at providing a measles rubella joint detection card for solve among the prior art difficult differentiation, detect for time long, detect with high costs problem.

In order to realize above-mentioned purpose and other relevant purposes, the utility model provides a measles rubella joint detection card, include: a bottom plate, a cover plate, sample adding cotton, a measles detection strip and a rubella detection strip; the cover plate is arranged on the bottom plate, so that an inner accommodating cavity is formed between the cover plate and the bottom plate; the sample adding cotton, the measles detection strip and the rubella detection strip are fixed on the bottom plate and are positioned in the internal accommodating cavity; the cover plate is provided with a sample adding window, a detection window, an ID area and a result interpretation area; the ID area and the result interpretation area are positioned on the right side of the detection window; the ID area and the result interpretation area are parallel up and down; the sample adding window is positioned above the sample adding cotton; the measles detection strip and the rubella detection strip are parallel to each other in position and are consistent in size and length; the position of the sample adding cotton is vertical to the measles detection strip and the rubella detection strip; the sample adding cotton comprises a sample pad and a colloidal gold combination pad; the sample pad is positioned above the colloidal gold bonding pad; the measles detection strip is connected with the colloidal gold combination pad; the rubella detection strip is connected with the colloidal gold combined pad; the measles detection strip comprises a chromatographic membrane 1 and a water absorption pad 1; the chromatographic membrane 1 and the water absorption pad 1 are sequentially fixed on the bottom plate and are connected with each other; the chromatographic membrane 1 is provided with an 'M' character and a 'V' character 1; the rubella detection strip comprises a chromatographic membrane 2 and a water absorption pad 2; the chromatographic membrane 2 and the water absorption pad 2 are sequentially fixed on the bottom plate and connected with each other; the chromatographic membrane 2 is provided with an R character and a V character 2; the detection windows are positioned on the chromatographic membranes 1 and 2.

Preferably, the colloidal gold conjugate pad is coated with a mouse anti-human IgM monoclonal antibody-colloidal gold marker.

Preferably, recombinant measles virus antigen is coated on the character 1 'V' on the chromatographic membrane 1; recombinant rubella virus antigen was coated on the chromatographic membrane 2 at the "V" character 2.

Preferably, the characters M and R are coated with goat anti-mouse IgG polyclonal antibody.

As mentioned above, the utility model discloses a measles rubella joint detection card has following beneficial effect: firstly, the measles and rubella combined detection card can detect two viruses of measles and rubella simultaneously by one-time sample adding, thereby reducing the steps of operation and detection; secondly, an M character and an R character which coat the goat anti-mouse IgG polyclonal antibody are arranged on the chromatographic membrane, so that whether the test paper strips are qualified or not is easy to observe, and the test items of the two test paper strips are easy to distinguish; and thirdly, the detection result is easy to interpret, the confusion of the M character, the R character and the V character can be avoided, the observation is clearer, and the misreading caused by the interference of blood can be avoided.

Drawings

Fig. 1 is a schematic structural view of the measles and rubella combined detection card provided by the utility model;

fig. 2 is a schematic top view of a bottom plate of the measles and rubella combined detection card provided by the present invention;

FIG. 3 is a schematic side view of the bottom plate of the measles and rubella combined detection card provided by the present invention;

FIG. 4 is a schematic diagram showing the negative result of the measles and rubella combined test card provided by the present invention;

FIG. 5 is a schematic diagram showing the positive measles result when the combined measles and rubella test card provided by the present invention is used;

in the figure, 1 bottom plate, 2 cover plate, 3 sample adding cotton, 4 measles detection strip, 5 rubella detection strip, 6 sample adding window, 7 detection window, 8ID zone, 9 result interpretation zone, 10 sample pad, 11 colloidal gold binding pad, 12 chromatographic membrane 1, 13 absorbent pad 1, 14

chromatographic membrane

2, 15 absorbent pad 2, 16 'M' character, 17 'V' character 1, 18 'R' character, 19 'V' character 2.

Detailed Description

Example 1

As shown in fig. 1 to fig. 5, the utility model provides a measles and rubella joint detection card, include: a bottom plate, a cover plate, sample adding cotton, a measles detection strip and a rubella detection strip; the cover plate is arranged on the bottom plate, so that an inner accommodating cavity is formed between the cover plate and the bottom plate; the sample adding cotton, the measles detection strip and the rubella detection strip are fixed on the bottom plate and are positioned in the internal accommodating cavity; the cover plate is provided with a sample adding window, a detection window, an ID area and a result interpretation area; the ID area and the result interpretation area are positioned on the right side of the detection window; the ID area and the result interpretation area are parallel up and down; the sample adding window is positioned above the sample adding cotton; the measles detection strip and the rubella detection strip are parallel to each other in position and are consistent in size and length; the position of the sample adding cotton is vertical to the measles detection strip and the rubella detection strip; the sample adding cotton comprises a sample pad and a colloidal gold combination pad; the sample pad is positioned above the colloidal gold bonding pad; the measles detection strip is connected with the colloidal gold combination pad; the rubella detection strip is connected with the colloidal gold combined pad; the measles detection strip comprises a chromatographic membrane 1 and a water absorption pad 1; the chromatographic membrane 1 and the water absorption pad 1 are sequentially fixed on the bottom plate and are connected with each other; the chromatographic membrane 1 is provided with an 'M' character and a 'V' character 1; the rubella detection strip comprises a chromatographic membrane 2 and a water absorption pad 2; the chromatographic membrane 2 and the water absorption pad 2 are sequentially fixed on the bottom plate and connected with each other; the chromatographic membrane 2 is provided with an R character and a V character 2; the detection windows are positioned on the chromatographic membrane 1 and the chromatographic membrane 2; a mouse anti-human IgM monoclonal antibody-colloidal gold marker is coated on the colloidal gold conjugate pad; recombinant measles virus antigen is coated on the V character on the chromatographic membrane 1; the V character on the chromatographic membrane 2 is coated with recombinant rubella virus antigen; the characters M and R are both coated with goat anti-mouse IgG polyclonal antibody.

Example 2

The utility model provides a pair of the utility model provides a measles rubella joint detection card, its structure is as in embodiment 1. When in use, 5 drops of a sample to be detected are dripped on the sample adding window, and the observation is waited for 5-10 min; observing the result in the detection window; if the measles detection strip and the rubella detection strip respectively have 'M' characters and 'R' characters, the detection is considered to be qualified, and the result can be interpreted; if the M character and the R character do not appear, the detection is considered to be unqualified, and the re-detection is needed; when the measles detection strip and the rubella detection strip are read, if the V characters do not appear on the measles detection strip and the rubella detection strip, the measles and rubella virus are considered not to be infected; if the measles test strip has V character 1 or/and the rubella test strip has V character 2, the measles test strip is judged to be positive or/and rubella positive, isolation treatment is needed, and the measles test strip is reported to a local health system, and nucleic acid or other tests can be carried out if necessary.

The above description is only for the specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art can be covered within the protection scope of the present invention without the changes or substitutions thought by the inventive work within the technical scope of the present invention. Therefore, the protection scope of the present invention should be subject to the protection scope defined by the claims.

Claims

1. A combined measles and rubella detection card is characterized by comprising: a bottom plate, a cover plate, sample adding cotton, a measles detection strip and a rubella detection strip; the cover plate is arranged on the bottom plate, so that an inner accommodating cavity is formed between the cover plate and the bottom plate; the sample adding cotton, the measles detection strip and the rubella detection strip are fixed on the bottom plate and are positioned in the internal accommodating cavity; the cover plate is provided with a sample adding window, a detection window, an ID area and a result interpretation area; the ID area and the result interpretation area are positioned on the right side of the detection window; the ID area and the result interpretation area are parallel up and down; the sample adding window is positioned above the sample adding cotton; the measles detection strip and the rubella detection strip are parallel to each other in position and are consistent in size and length; the position of the sample adding cotton is vertical to the measles detection strip and the rubella detection strip; the sample adding cotton comprises a sample pad and a colloidal gold combination pad; the sample pad is positioned above the colloidal gold bonding pad; the measles detection strip is connected with the colloidal gold combination pad; the rubella detection strip is connected with the colloidal gold combined pad; the measles detection strip comprises a chromatographic membrane 1 and a water absorption pad 1; the chromatographic membrane 1 and the water absorption pad 1 are sequentially fixed on the bottom plate and are connected with each other; the chromatographic membrane 1 is provided with an 'M' character and a 'V' character 1; the rubella detection strip comprises a chromatographic membrane 2 and a water absorption pad 2; the chromatographic membrane 2 and the water absorption pad 2 are sequentially fixed on the bottom plate and connected with each other; the chromatographic membrane 2 is provided with an R character and a V character 2; the detection windows are positioned on the chromatographic membranes 1 and 2.

2. The combined measles and rubella test card as claimed in claim 1, wherein: the colloidal gold combined pad is coated with a mouse anti-human IgM monoclonal antibody-colloidal gold marker.

3. The combined measles and rubella test card as claimed in claim 1, wherein: recombinant measles virus antigen is coated on the V character 1 on the chromatographic membrane 1; recombinant rubella virus antigen was coated on the chromatographic membrane 2 at the "V" character 2.

4. The combined measles and rubella test card as claimed in claim 1, wherein: the characters M and R are both coated with goat anti-mouse IgG polyclonal antibody.