CN211357820U - Be used for synthetic integral type crystal separation device of using of pranoprofen - Google Patents
Be used for synthetic integral type crystal separation device of using of pranoprofen Download PDFInfo
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- CN211357820U CN211357820U CN201922236050.0U CN201922236050U CN211357820U CN 211357820 U CN211357820 U CN 211357820U CN 201922236050 U CN201922236050 U CN 201922236050U CN 211357820 U CN211357820 U CN 211357820U
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- separating cylinder
- pranoprofen
- separation
- fixedly connected
- bevel gear
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- 238000000926 separation method Methods 0.000 title claims abstract description 66
- TVQZAMVBTVNYLA-UHFFFAOYSA-N Pranoprofen Chemical compound C1=CC=C2CC3=CC(C(C(O)=O)C)=CC=C3OC2=N1 TVQZAMVBTVNYLA-UHFFFAOYSA-N 0.000 title claims abstract description 26
- 229960003101 pranoprofen Drugs 0.000 title claims abstract description 26
- 239000013078 crystal Substances 0.000 title claims abstract description 19
- 239000007788 liquid Substances 0.000 claims abstract description 46
- 239000000463 material Substances 0.000 claims abstract description 30
- 230000015572 biosynthetic process Effects 0.000 claims abstract description 15
- 238000003786 synthesis reaction Methods 0.000 claims abstract description 15
- 238000007789 sealing Methods 0.000 claims abstract description 11
- 230000005540 biological transmission Effects 0.000 claims description 17
- 238000007599 discharging Methods 0.000 claims description 8
- 238000002425 crystallisation Methods 0.000 abstract description 10
- 230000008025 crystallization Effects 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 6
- 239000000203 mixture Substances 0.000 abstract description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 239000002245 particle Substances 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 102000004005 Prostaglandin-endoperoxide synthases Human genes 0.000 description 2
- 108090000459 Prostaglandin-endoperoxide synthases Proteins 0.000 description 2
- 206010039705 Scleritis Diseases 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000012043 crude product Substances 0.000 description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
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- 230000004054 inflammatory process Effects 0.000 description 2
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- 238000011084 recovery Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- YAWVFJYLSIMLAY-UHFFFAOYSA-N 2-acetyloxybenzoic acid;2-[4-(2-methylpropyl)phenyl]propanoic acid Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O.CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 YAWVFJYLSIMLAY-UHFFFAOYSA-N 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 1
- 206010022941 Iridocyclitis Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 206010034464 Periarthritis Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
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- 230000004075 alteration Effects 0.000 description 1
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- 201000004612 anterior uveitis Diseases 0.000 description 1
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- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 208000010217 blepharitis Diseases 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
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- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- IQLUYYHUNSSHIY-HZUMYPAESA-N eicosatetraenoic acid Chemical class CCCCCCCCCCC\C=C\C=C\C=C\C=C\C(O)=O IQLUYYHUNSSHIY-HZUMYPAESA-N 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
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- 229960001680 ibuprofen Drugs 0.000 description 1
- 229940088523 ibuprofen injection Drugs 0.000 description 1
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- 201000001245 periodontitis Diseases 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 208000020029 respiratory tract infectious disease Diseases 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 238000009987 spinning Methods 0.000 description 1
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- 238000001291 vacuum drying Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The utility model discloses an integrated crystallization and separation device for pranoprofen synthesis, which comprises a shell and a motor device, wherein the upper end of the shell is fixedly connected with a feed inlet, a material guide channel is fixedly arranged on the upper side inside the shell, a material discharge channel is fixedly arranged at the bottom of the material guide channel, a first separation barrel is arranged at the bottom of the material discharge channel, a second separation barrel is arranged on the left side of the first separation barrel, the first separation barrel is arranged on the upper side of a fixed plate, and a seal box is fixedly connected to the lower end of the fixed plate; the motor device is fixedly arranged inside the sealing box through the base. The integrated crystallization separation device for pranoprofen synthesis has the advantages that a solid-liquid mixture rotates inside the two groups of separation cylinders, heavy crystal components stay inside the two groups of separation cylinders, and light component liquid flows into the outer sides of the separation cylinders along with the through holes on the separation cylinders, so that solid-liquid separation is realized; the solid-liquid separation effect of the device is ensured.
Description
Technical Field
The utility model relates to a synthetic equipment science and technology field of pranoprofen specifically is a be used for synthetic integral type crystallization separator of using of pranoprofen.
Background
Pranoprofen belongs to propionic acid non-steroidal anti-inflammatory drugs, and has the action mechanism of mainly inhibiting the activity of Cyclooxygenase (COX), blocking the synthesis of eicosatetraenoic acid derivatives, inhibiting the synthesis of prostaglandins and relieving inflammatory reaction; the anti-inflammatory effect of the aspirin-ibuprofen injection is better than that of aspirin and ibuprofen, and the adverse reaction rate is low and slight; the clinical main local medicine is used for symptomatic treatment of external eyes and anterior parts of eyes, such as blepharitis, conjunctivitis, keratitis, scleritis, superficial scleritis and iridocyclitis; oral administration is suitable for (1) anti-inflammatory and analgesic effects of chronic rheumatoid arthritis, osteoarthritis, lumbago, scapulohumeral periarthritis, neck-shoulder-wrist syndrome, periodontitis, and gout; (2) analgesia and inflammation diminishing after operation, trauma and tooth extraction; (3) antipyretic and analgesic effects of acute upper respiratory infection, and the mode of processing the pranoprofen crude product into fine products is as follows: adding absolute ethyl alcohol and purified water into a 200L reaction kettle, starting stirring, adding a pranoprofen crude product, heating until reflux dissolution is achieved, performing hot filtration, cooling a filtrate to room temperature, crystallizing for more than 5 hours, performing filter spinning, washing the reaction kettle and a filter cake with ethanol, performing spin-drying, and performing vacuum drying at 50 ℃ for 5-6 hours to obtain about 4kg of pranoprofen, wherein the yield is 85-95%; wherein need to carry out the separation work to the crystallization in the filtrate, prior art's crystallization separator, there is the inefficiency of separation, the poor shortcoming of effect of separation.
In order to solve the disadvantages existing in the current market, there is a need for an improved crystallization separation apparatus.
SUMMERY OF THE UTILITY MODEL
The utility model provides a technical problem lie in overcoming the defect that mentions in the background art, provide one kind and be used for synthetic integral type crystallization separator of using of pranoprofen. The first separation cylinder, the second separation cylinder and the liquid storage tank are provided with a solid-liquid mixture which rotates in the two groups of separation cylinders, heavy crystal components stay in the two groups of separation cylinders, and light component liquid flows into the outer sides of the separation cylinders along with the through holes on the separation cylinders, so that solid-liquid separation is realized; the solid-liquid separation effect of the device is ensured.
In order to achieve the above object, the utility model provides a following technical scheme: an integrated crystallization and separation device for pranoprofen synthesis comprises a shell and a motor device, wherein a feed inlet is fixedly connected to the upper end of the shell, a material guide channel is fixedly mounted on the upper side inside the shell, a material discharge channel is fixedly mounted at the bottom of the material guide channel, a first separation barrel is mounted at the bottom of the material discharge channel, a second separation barrel is mounted on the left side of the first separation barrel, the first separation barrel is arranged on the upper side of a fixed plate, and a seal box is fixedly connected to the lower end of the fixed plate;
the motor device is fixedly arranged in the sealing box through the base, the lower end of the fixed shaft lever is fixedly arranged in the sealing box through a bearing, the upper end of the fixed shaft lever penetrates through the fixed plate through the bearing to be fixedly connected with the second separating cylinder, the liquid storage tank is arranged at the bottom of the shell, and the lower end of the sealing box is fixedly arranged at the bottom of the liquid storage tank through the fixing frame; the rod body of the first bevel gear is fixed inside the sealing box through a bearing, a transmission gear is fixedly connected to the rod body of the first bevel gear, and a liquid outlet hole is formed in the fixing plate.
Preferably, the lower end of the feeding hole is arranged in a bowl shape, and the lower end of the feeding hole is arranged inside the material guide channel.
Preferably, an inclined surface is arranged in the material guide channel, and the inclined surface is inclined by 45 degrees.
Preferably, two sets of discharge openings have been seted up to the lower extreme of guide passageway, and the equal fixedly connected with filter in two sets of discharge openings, and the discharge opening is linked together with discharge passageway simultaneously.
Preferably, the discharging channels are arranged in a circular truncated cone shape, the discharging channels are arranged in two groups on the lower side of the material guide channel, and the lower ends of the two groups of discharging channels respectively extend into the first separating cylinder and the second separating cylinder.
Preferably, the outer sides of the first separating cylinder and the second separating cylinder are fixedly arranged at the lower side in the shell through bearings, the lower ends of the first separating cylinder and the second separating cylinder are fixedly connected with fixed shaft levers, and second bevel gears are arranged on the fixed shaft levers; the limiting plates in the shape of the inverted V are fixedly connected inside the first separating cylinder and the second separating cylinder, through holes are formed in the surfaces of the first separating cylinder and the second separating cylinder, and the diameter of each through hole is smaller than the size of the pranoprofen crystal.
Preferably, both ends of the transmission gear are fixedly connected with a first bevel gear, the first bevel gear is matched with the second bevel gear in size, and the first bevel gear is meshed with the second bevel gear.
Preferably, the rotor of the motor device is fixedly connected with the worm through the coupler, the worm is matched with the transmission gear in size, and the transmission gear is meshed with the worm.
Compared with the prior art, the beneficial effects of the utility model are that:
1. limiting plates are arranged in the two groups of separating cylinders, so that liquid can be prevented from flying out from the upper ends of the two groups of separating cylinders;
2. liquid is collected in the liquid storage tank through the liquid outlet holes through the through holes on the two groups of separating cylinders, and the liquid material collected in the liquid storage tank can enter the feeding hole again through the recovery pipe in the liquid storage tank to carry out circular separation operation, so that the solid-liquid separation effect of the device is ensured;
3. the solid-liquid mixture rotates in the two-component separation cylinder, the heavy crystal component stays in the two-component separation cylinder, and the light component liquid flows into the outer side of the separation cylinder along with the through holes on the separation cylinder and is collected in the liquid storage tank, so that the solid-liquid separation work is realized.
Drawings
FIG. 1 is a front view of the structure of the present invention;
FIG. 2 is a schematic cross-sectional view of the structure B-B of the present invention;
FIG. 3 is a schematic sectional view of the structure A-A of the present invention;
FIG. 4 is an external view of the first separating cylinder of the present invention;
fig. 5 is a schematic view of the transmission structure of the first bevel gear and the second bevel gear of the present invention.
Reference numbers in the figures: 1. a housing; 2. a feed inlet; 3. a material guide channel; 4. an inclined surface; 5. a discharge channel; 6. a limiting plate; 7. a first separation drum; 8. a fixing plate; 9. a sealing box; 10. a liquid storage tank; 11. a fixed mount; 12. a worm; 13. a transmission gear; 14. a first bevel gear; 15. a second bevel gear; 16. fixing the shaft lever; 17. a motor device; 18. a second separation drum; 19. a filter plate; 20. and a liquid outlet hole.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-5, the present invention provides a technical solution: an integrated crystallization and separation device for pranoprofen synthesis comprises a shell 1 and a motor device 17, wherein the upper end of the shell 1 is fixedly connected with a feed inlet 2, a material guide channel 3 is fixedly mounted on the upper side inside the shell 1, a material discharge channel 5 is fixedly mounted at the bottom of the material guide channel 3, a first separation cylinder 7 is mounted at the bottom of the material discharge channel 5, the lower end of the feed inlet 2 is arranged in a bowl shape, and the lower end of the feed inlet 2 is arranged inside the material guide channel 3; an inclined surface 4 is arranged in the material guide channel 3, and the inclined surface 4 is inclined by 45 degrees; the left side of the first separating cylinder 7 is provided with a second separating cylinder 18, the first separating cylinder 7 is arranged on the upper side of the fixed plate 8, and the lower end of the fixed plate 8 is fixedly connected with a seal box 9; two groups of discharge holes are formed in the lower end of the material guide channel 3, filter plates 19 are fixedly connected inside the two groups of discharge holes, and the discharge holes are communicated with the discharge channel 5; the discharge channels 5 are arranged in a circular truncated cone shape, two groups of discharge channels 5 are arranged on the lower side of the material guide channel 3, and the lower ends of the two groups of discharge channels 5 respectively extend into the first separating cylinder 7 and the second separating cylinder 18; the outer sides of the first separating cylinder 7 and the second separating cylinder 18 are fixedly arranged at the lower side in the shell 1 through bearings, the lower ends of the first separating cylinder 7 and the second separating cylinder 18 are fixedly connected with a fixed shaft lever 16, and a second bevel gear 15 is arranged on the fixed shaft lever 16; the first separating cylinder 7 and the second separating cylinder 18 are fixedly connected with limiting plates 6 in an inverted-splayed shape inside, through holes are formed in the surfaces of the first separating cylinder 7 and the second separating cylinder 18, and the diameter of each through hole is smaller than the size of the pranoprofen crystal; both ends of the transmission gear 13 are fixedly connected with a first bevel gear 14, the first bevel gear 14 is matched with a second bevel gear 15 in size, and the first bevel gear 14 is meshed with the second bevel gear 15; the motor device 17 is fixedly arranged in the sealing box 9 through the base, the lower end of the fixed shaft lever 16 is fixedly arranged in the sealing box 9 through a bearing, meanwhile, the upper end of the fixed shaft lever 16 penetrates through the fixed plate 8 through the bearing to be fixedly connected with the second separating cylinder 18, the liquid storage tank 10 is arranged at the bottom of the shell 1, and the lower end of the sealing box 9 is fixedly arranged at the bottom of the liquid storage tank 10 through the fixed frame 11; a rod body of the first bevel gear 14 is fixed inside the seal box 9 through a bearing, a transmission gear 13 is fixedly connected to the rod body of the first bevel gear 14, and a liquid outlet hole 20 is formed in the fixed plate 8; the rotor of the motor device 17 is fixedly connected with the worm 12 through a coupler, the worm 12 is matched with the transmission gear 13 in size, and meanwhile, the transmission gear 13 is meshed with the worm 12;
as shown in fig. 1-3: when the first separating cylinder 7 and the second separating cylinder 18 rotate, the limiting plates 6 are arranged in the two groups of separating cylinders, so that liquid can be prevented from flying out from the upper ends of the two groups of separating cylinders, and sealing doors are arranged on the first separating cylinder 7 and the second separating cylinder 18 and used for taking out crystal particles;
as shown in fig. 1: when the first separation cylinder 7 and the second separation cylinder 18 rotate, liquid is collected inside the liquid storage tank 10 through the liquid outlet hole 20 through the through hole on the liquid storage tank, and the liquid collected inside the liquid storage tank 10 can enter the feed inlet 2 again through the recovery pipe inside the liquid storage tank to perform circulating separation operation, so that the solid-liquid separation effect of the device is ensured.
When the integrated crystallization and separation device for pranoprofen synthesis is used, a solid-liquid mixture is discharged into the material guide channel 3 through the material inlet 2, meanwhile, the filtration is carried out through the filter plate 19, large-particle impurities are filtered and then enter the first separation cylinder 7 and the second separation cylinder 18 through the material outlet channel 5 below the large-particle impurities respectively, at the moment, a power switch of the motor device 17 is turned on, the motor device 17 drives the transmission gear 13 to rotate through the worm 12, the transmission gear 13 drives the second bevel gear 15 to rotate through the first bevel gears 14 on the two sides, the first separation cylinder 7 and the second separation cylinder 18 rotate along with the transmission gear, the solid-liquid mixture rotates inside the two separation cylinders, the heavy crystal component stays inside the two separation cylinders, the light component liquid flows into the outer sides of the separation cylinders along with the through holes on the separation cylinders and is collected inside the liquid storage tank 10 through the liquid outlet hole 20, completing the solid-liquid separation work; this is the entire process of the operation of the integrated crystal separation apparatus for pranoprofen synthesis.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. The utility model provides a be used for synthetic integral type crystal separation device of pranoprofen, includes casing (1) and motor device (17), its characterized in that: the feeding device is characterized in that a feeding hole (2) is fixedly connected to the upper end of the shell (1), a material guide channel (3) is fixedly mounted on the upper side inside the shell (1), a material discharging channel (5) is fixedly mounted at the bottom of the material guide channel (3), a first separating cylinder (7) is mounted at the bottom of the material discharging channel (5), a second separating cylinder (18) is mounted on the left side of the first separating cylinder (7), the first separating cylinder (7) is arranged on the upper side of a fixing plate (8), and a sealing box (9) is fixedly connected to the lower end of the fixing plate (8);
the motor device (17) is fixedly arranged inside the seal box (9) through the base, the lower end of the fixed shaft lever (16) is fixedly arranged inside the seal box (9) through a bearing, meanwhile, the upper end of the fixed shaft lever (16) penetrates through the fixed plate (8) through the bearing to be fixedly connected with the second separation barrel (18), the bottom of the shell (1) is provided with a liquid storage tank (10), and the lower end of the seal box (9) is fixedly arranged at the bottom of the liquid storage tank (10) through the fixed frame (11); the rod body of the first bevel gear (14) is fixed inside the seal box (9) through a bearing, a transmission gear (13) is fixedly connected onto the rod body of the first bevel gear (14), and a liquid outlet hole (20) is formed in the fixing plate (8).
2. The integrated crystal separation device for pranoprofen synthesis according to claim 1, wherein: the lower end of the feed inlet (2) is arranged in a bowl shape, and the lower end of the feed inlet (2) is arranged inside the material guide channel (3).
3. The integrated crystal separation device for pranoprofen synthesis according to claim 1, wherein: an inclined surface (4) is arranged inside the material guide channel (3), and the inclined surface (4) is inclined by 45 degrees.
4. The integrated crystal separation device for pranoprofen synthesis according to claim 1, wherein: two sets of discharge openings have been seted up to the lower extreme of guide passageway (3), and the equal fixedly connected with filter (19) of two sets of discharge openings inside, and the discharge opening is linked together with discharge passageway (5) simultaneously.
5. The integrated crystal separation device for pranoprofen synthesis according to claim 1, wherein: the discharging channels (5) are arranged in a circular truncated cone shape, the discharging channels (5) are arranged in two groups on the lower side of the material guiding channel (3), and the lower ends of the two groups of discharging channels (5) respectively extend into the first separating cylinder (7) and the second separating cylinder (18).
6. The integrated crystal separation device for pranoprofen synthesis according to claim 1, wherein: the outer sides of the first separating cylinder (7) and the second separating cylinder (18) are fixedly arranged at the lower side in the shell (1) through bearings, the lower ends of the first separating cylinder (7) and the second separating cylinder (18) are fixedly connected with a fixed shaft lever (16), and a second bevel gear (15) is arranged on the fixed shaft lever (16); the inside limiting plate (6) of the shape of the Chinese character 'ba' of falling is all fixedly connected with of first separating cylinder (7) and second separating cylinder (18), and the through-hole has all been seted up on the surface of first separating cylinder (7) and second separating cylinder (18), and the diameter of through-hole is less than the size of pranoprofen crystal.
7. The integrated crystal separation device for pranoprofen synthesis according to claim 1, wherein: and both ends of the transmission gear (13) are fixedly connected with a first bevel gear (14), the first bevel gear (14) is matched with the second bevel gear (15) in size, and the first bevel gear (14) is meshed with the second bevel gear (15).
8. The integrated crystal separation device for pranoprofen synthesis according to claim 1, wherein: the rotor of the motor device (17) is fixedly connected with the worm (12) through a coupler, the worm (12) is matched with the transmission gear (13) in size, and meanwhile the transmission gear (13) is meshed with the worm (12).
Priority Applications (1)
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CN201922236050.0U CN211357820U (en) | 2019-12-13 | 2019-12-13 | Be used for synthetic integral type crystal separation device of using of pranoprofen |
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CN201922236050.0U CN211357820U (en) | 2019-12-13 | 2019-12-13 | Be used for synthetic integral type crystal separation device of using of pranoprofen |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113082768A (en) * | 2021-04-20 | 2021-07-09 | 安徽省圣丹生物化工有限公司 | Two drum structures for centrifugal extraction machine are used in weedicide production |
CN113956264A (en) * | 2021-12-06 | 2022-01-21 | 中山万汉制药有限公司 | Novel pranoprofen crystal form and preparation method thereof |
-
2019
- 2019-12-13 CN CN201922236050.0U patent/CN211357820U/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113082768A (en) * | 2021-04-20 | 2021-07-09 | 安徽省圣丹生物化工有限公司 | Two drum structures for centrifugal extraction machine are used in weedicide production |
CN113956264A (en) * | 2021-12-06 | 2022-01-21 | 中山万汉制药有限公司 | Novel pranoprofen crystal form and preparation method thereof |
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Granted publication date: 20200828 |