CN211318197U - Fluorescence immunoassay appearance - Google Patents
Fluorescence immunoassay appearance Download PDFInfo
- Publication number
- CN211318197U CN211318197U CN201922303601.0U CN201922303601U CN211318197U CN 211318197 U CN211318197 U CN 211318197U CN 201922303601 U CN201922303601 U CN 201922303601U CN 211318197 U CN211318197 U CN 211318197U
- Authority
- CN
- China
- Prior art keywords
- detection
- module
- card
- shell
- dimensional code
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The utility model discloses a fluorescence immunoassay analyzer, which comprises a shell and a detection component arranged in the shell; the shell is formed by buckling an upper part and a lower part together; a card slot for inserting the detection card is arranged in the shell; the detection assembly comprises an MCU, and an LED board, an image acquisition module, a communication module, a photoelectric switch, an LCD, a memory, a two-dimensional code reading module and a power supply module which are connected with the MCU; the image acquisition module comprises a linear array ccd, a cylindrical lens and a lens group which are sequentially connected from back to front; the LED plate is arranged between the clamping groove and the lens group, and a detection hole is formed in the position, corresponding to a detection area on a detection card inserted into the clamping groove, of the LED plate; the photoelectric switch is arranged on the LED board and used for detecting the insertion state of the detection card; the two-dimensional code reading module is used for reading the two-dimensional code on the detection card. The image acquisition module of this application is avoided scanning the moving part as the sensor by linear array ccd, and the power saving is fast, can realize that the time-resolved fluorescence is accurate to be read.
Description
Technical Field
The utility model belongs to the technical field of fluorescence immunoassay technique and specifically relates to a fluorescence immunoassay appearance is related to.
Background
The Time-resolved fluoroimmunoassay (TRFIA) is a non-isotopic immunoassay developed in the last decade, is the most sensitive microanalysis technology at present, has the sensitivity as high as 10^ (12) g/ml, and is 3 orders of magnitude higher than the Radioimmunoassay (RIA). According to the method, lanthanide is used for marking an antigen or an antibody, fluorescence is measured by using a time resolution technology according to the luminescent characteristics of lanthanide chelate, and two parameters of wavelength and time are detected simultaneously for signal resolution, so that the interference of non-specific fluorescence can be effectively eliminated, and the analysis sensitivity is greatly improved. Because of its high sensitivity, it is widely used clinically.
Many complexes and proteins in biological fluids and serum can themselves fluoresce, and the sensitivity of fluorescence detection using conventional chromophores is severely compromised. Most background fluorescence signals are present for short periods of time, so combining long decay lifetime markers with time-resolved fluorescence techniques minimizes temporal fluorescence interference.
The fluorescence lifetime of common fluorescent markers is very short, and the excitation light disappears and the fluorescence also disappears. However, rare earth metals (Eu, Tb, Sm and Dy) have long fluorescence lifetime which can reach 1-2 ms and can meet the measurement requirement, so that a time-resolved fluorescence analysis method is generated, namely an analysis method for measuring the fluorescence intensity after the excitation light is turned off by using a long-acting fluorescence marker.
The current fluorescence analyzer adopts the optical fiber scanning principle and has the following defects:
1) the scanning process is slow, and usually, only ten seconds are needed to complete one inspection;
2) scanning has step size control problem (jitter or step loss causes signal instability);
3) the optical fiber is often thin, so that the acquisition width is insufficient, and if the acquisition width is too wide, the signal is distorted;
4) the whole machine is large in size and is not beneficial to being made into a portable machine; the motor has high power consumption and short standby time when the battery is used for supplying power;
5) the standard curve of the reagent and the reagent card need to be matched manually, and errors are easy to occur.
The information disclosed in this background section is only for enhancement of understanding of the general background of the application and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person skilled in the art.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a fluorescence immunoassay appearance to solve the technical problem who exists among the prior art.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the utility model provides a fluorescence immunoassay analyzer, which comprises a shell and a detection component arranged in the shell; wherein the content of the first and second substances,
the shell is formed by buckling an upper part and a lower part together; a card slot for inserting the detection card is arranged in the shell;
the detection assembly comprises an MCU, and an LED board, an image acquisition module, a communication module, a radio frequency module, a photoelectric switch, an LCD, a memory, a two-dimensional code reading module and a power supply module which are connected with the MCU; the image acquisition module comprises a linear array ccd, a cylindrical lens and a lens group which are sequentially connected from back to front;
the LED plate is arranged between the clamping groove and the lens group, and a detection hole is formed in the position, corresponding to a detection area on a detection card inserted into the clamping groove, of the LED plate;
the photoelectric switch is arranged on the LED board and used for detecting the insertion state of the detection card;
the two-dimensional code reading module is used for reading the two-dimensional code on the detection card.
As a further technical solution, the rear end of the lens group is provided with an optical filter.
As a further technical scheme, a detection card taking-out device is arranged in the shell in a matching manner with the clamping groove, the detection card taking-out device comprises a pressing rod and a prying plate, the middle part of the prying plate is hinged in the shell, and the front end of the prying plate is opposite to the end part of the detection card inserted into the clamping groove; the rear end of the prying plate is opposite to the front end of the pressing rod; a limiting block is arranged in the middle of the pressing rod, and limiting plates are arranged in the shells on the front side and the rear side of the limiting block; and a reset spring is sleeved on the pressing rod.
As a further technical solution, the LCD is disposed on a front end surface of the housing.
As a further technical solution, the communication module is a WiFi module, a bluetooth module or an I/O port, and the analyzer synchronizes network information through the communication module.
As a further technical scheme, the power module comprises two lithium batteries, and the lithium batteries are matched with each other, wherein a charging interface connected with the lithium batteries is arranged on the upper end face of the shell.
As a further technical solution, the detection assembly further includes a radio frequency module.
Adopt above-mentioned technical scheme, the utility model discloses following beneficial effect has:
the image acquisition module of this application is avoided scanning the moving part as the sensor by linear array ccd, and the power saving is fast, can realize that the time-resolved fluorescence is accurate to be read.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the technical solutions in the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a structural diagram of a detection assembly provided in an embodiment of the present invention;
fig. 2 is a schematic diagram of an internal structure of a fluorescence immunoassay analyzer according to an embodiment of the present invention;
fig. 3 is a top view of the internal structure of the fluorescence immunoassay analyzer provided in the embodiment of the present invention;
fig. 4 is a sectional view taken along line a-a in fig. 3.
Icon: 1-linear array ccd, 2-cylindrical mirror, 3-lens group, 4-LED plate, 5-detection card, 6-detection hole, 7-photoelectric switch, 8-two-dimensional code reading module, 9-two-dimensional code, 10-pressing rod, 11-pry plate, 12-limiting block, 13-limiting plate, 14-reset spring, 15-lithium battery, 16-limiting plate.
Detailed Description
The technical solution of the present invention will be described clearly and completely with reference to the accompanying drawings, and obviously, the described embodiments are some, but not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
The following detailed description of the embodiments of the present invention will be made with reference to the accompanying drawings. It is to be understood that the description of the embodiments herein is for purposes of illustration and explanation only and is not intended to limit the invention.
Referring to fig. 1 to 4, the present embodiment provides a fluorescence immunoassay analyzer, which includes a housing and a detection assembly disposed in the housing; wherein the content of the first and second substances,
the shell is formed by buckling an upper part and a lower part together; a card slot for inserting the detection card 5 is arranged in the shell;
the detection assembly comprises an MCU, and an LED board, an image acquisition module, a communication module, a radio frequency module, a photoelectric switch, an LCD, a memory, a two-dimensional code reading module and a power supply module which are connected with the MCU; the image acquisition module comprises a linear array ccd1, a cylindrical lens 2 and a lens group 3 which are sequentially connected from back to front;
the LED plate 4 is arranged between the clamping groove and the lens group 3, and a detection hole 6 is formed in the LED plate 4 at a position corresponding to a detection area on a detection card inserted into the clamping groove;
the photoelectric switch 7 is arranged on the LED board and used for detecting the insertion state of the detection card 5;
the two-dimensional code reading module 8 is used for reading the two-dimensional code 9 on the detection card.
In the application, the camera takes the linear array ccd as a sensor, so that a moving part can be prevented from being scanned, electricity is saved, the speed is high, and accurate reading of time-resolved fluorescence can be realized; more light rays can be converged by arranging the cylindrical mirror 2, so that the detection result is more reliable; by arranging the detection hole 6, the light intensity is moderate when the image acquisition module acquires information, and interference light is avoided; the insertion of the automatic identification detection card is realized by arranging the photoelectric switch; the information on the detection card can be read through the two-dimensional code reading module, the information is compared with the information stored in the local machine, and if the local machine does not exist, the communication module is used for automatic synchronization from the network.
In this embodiment, as a further technical solution, an optical filter is disposed at a rear end of the lens group.
In this embodiment, as a further technical solution, a detection card taking-out device is disposed in the housing in cooperation with the card slot, the detection card taking-out device includes a pressing rod 10 and a pry plate 11, a middle portion of the pry plate 11 is hinged in the housing, and a front end of the pry plate 11 is opposite to an end portion of the detection card 5 inserted into the card slot; the rear end of the pry plate 11 is opposite to the front end of the pressing rod 10; a limiting block 12 is arranged in the middle of the pressing rod 10, and limiting plates 13 are arranged in the shells on the front side and the back side of the limiting block 12; and a return spring 14 is sleeved on the pressing rod 10. Preferably, a limit plate 16 is provided in the rear housing of the pry plate 11. The detection card taking-out device is arranged to realize convenient taking-out of the detection card, and when the detection card taking-out device is used, the pressing rod 10 is pressed inwards, so that the front end of the pry plate 11 is driven to eject the detection card 5; and the automatic return of the pressing lever 10 is achieved by providing the return spring 14.
In this embodiment, as a further technical solution, the LCD is disposed on the front end surface of the housing, and preferably, the LCD is embedded on the front end surface of the housing.
In this embodiment, as a further technical solution, the communication module is a WiFi module, a bluetooth module, or an I/O port, and the analyzer synchronizes network information through the communication module.
In this embodiment, as a further technical scheme, power module includes two sections lithium cell 15, and the cooperation lithium cell 15 is in the up end of casing is provided with the interface that charges of being connected with the lithium cell.
The working flow of the fluorescence immunoassay analyzer is as follows:
working mode 1: two-dimensional code mode
1. After starting up, inserting a detection card;
2. the photoelectric switch recognizes that a card is inserted, and informs the two-dimensional code module to read the two-dimensional code of the detection card;
3. mcu comparing the two-dimensional code information to call out the standard curve parameters of the corresponding reagent (the standard curve parameters are stored in the memory in advance). If the local computer does not store the curve, downloading the curve from the server. Or imported by an RFID card;
4. and finishing detection and calculation of the detection card and storing the result.
The working mode 2 is as follows: RFID card mode (for reagent without two-dimension code)
1. After the system is started, swiping an RFID card, and reading a specified standard curve;
2. inserting the detection card, and recognizing that the card is inserted by the photoelectric switch;
3. and finishing detection and calculation of the detection card and storing the result.
To sum up, the utility model discloses be provided with photoelectric sensor and wifi bluetooth module, the standard curve of the direct associative reagent of information on the accessible reagent card. And when the insertion of the reagent card is detected, the reagent curve matching and result reading are automatically completed. Only one card inserting operation is needed, and any operation key does not need to be pressed on the instrument.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention.
Claims (7)
1. A fluorescence immunoassay analyzer is characterized by comprising a shell and a detection assembly arranged in the shell; wherein the content of the first and second substances,
the shell is formed by buckling an upper part and a lower part together; a card slot for inserting the detection card is arranged in the shell;
the detection assembly comprises an MCU, and an LED board, an image acquisition module, a communication module, a photoelectric switch, an LCD, a memory, a two-dimensional code reading module and a power supply module which are connected with the MCU; the image acquisition module comprises a linear array ccd, a cylindrical lens and a lens group which are sequentially connected from back to front;
the LED plate is arranged between the clamping groove and the lens group, and a detection hole is formed in the position, corresponding to a detection area on a detection card inserted into the clamping groove, of the LED plate;
the photoelectric switch is arranged on the LED board and used for detecting the insertion state of the detection card;
the two-dimensional code reading module is used for reading the two-dimensional code on the detection card.
2. The fluoroimmunoassay analyzer of claim 1, wherein a rear end of the lens group is provided with an optical filter.
3. The fluoroimmunoassay analyzer of claim 1, wherein a test card removing device is provided in the housing in cooperation with the card slot, the test card removing device comprising a pressing lever and a pry plate, a middle portion of the pry plate being hinged in the housing, a front end of the pry plate being opposite to an end portion of the test card inserted into the card slot; the rear end of the prying plate is opposite to the front end of the pressing rod; a limiting block is arranged in the middle of the pressing rod, and limiting plates are arranged in the shells on the front side and the rear side of the limiting block; and a reset spring is sleeved on the pressing rod.
4. The fluoroimmunoassay analyzer of claim 1, wherein the LCD is disposed on a front face of the housing.
5. The fluoroimmunoassay analyzer of claim 1, wherein the communication module is a WiFi module, a bluetooth module, or an I/O port, and the analyzer synchronizes network information through the communication module.
6. The fluoroimmunoassay analyzer of claim 1, wherein the power module comprises two lithium batteries, and a charging interface connected with the lithium batteries is arranged on the upper end face of the housing in cooperation with the lithium batteries.
7. The fluoroimmunoassay analyzer of claim 1, wherein the detection assembly further comprises a radio frequency module.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922303601.0U CN211318197U (en) | 2019-12-20 | 2019-12-20 | Fluorescence immunoassay appearance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922303601.0U CN211318197U (en) | 2019-12-20 | 2019-12-20 | Fluorescence immunoassay appearance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211318197U true CN211318197U (en) | 2020-08-21 |
Family
ID=72062238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201922303601.0U Active CN211318197U (en) | 2019-12-20 | 2019-12-20 | Fluorescence immunoassay appearance |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN211318197U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024100683A1 (en) * | 2022-11-11 | 2024-05-16 | Mylab Discovery Solutions Private Limited | A system for a lateral fluorescence immunoassay analyzer and a method thereof |
-
2019
- 2019-12-20 CN CN201922303601.0U patent/CN211318197U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024100683A1 (en) * | 2022-11-11 | 2024-05-16 | Mylab Discovery Solutions Private Limited | A system for a lateral fluorescence immunoassay analyzer and a method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110849860A (en) | Fluorescence immunoassay appearance | |
| CN211318197U (en) | Fluorescence immunoassay appearance | |
| CN105306584A (en) | System and method for synchronizing reading progresses of paper-made book and electronic book | |
| CN112750216A (en) | Novel parking space detection video pile and detection system thereof | |
| CN204422530U (en) | Biological chip reading apparatus | |
| CN216771760U (en) | Fluorescence immunochromatography test paper card for detecting N-terminal brain natriuretic peptide precursor | |
| CN210222032U (en) | Medical hand-held type fluorescence immunoassay appearance | |
| CN109900894A (en) | A kind of hospital handheld formula fluorescence immunity analyzer | |
| CN115165830A (en) | Ratio type up-conversion fluorescence detection device and method based on micro-fluidic chip | |
| CN207164065U (en) | A kind of Immunofluorescence test device | |
| CN215525819U (en) | Portable fluorescence immunoassay appearance | |
| CN219657493U (en) | Portable ketamine fluorescent test strip rapid detection device | |
| CN210199117U (en) | Medical ten-channel colloidal gold analyzer | |
| CN208984529U (en) | A kind of multi-functional dry type POCT equipment | |
| CN111337683A (en) | Portable HIV detection device | |
| CN1129100C (en) | Non-contact data-logging arriving device and method | |
| CN211553850U (en) | Multifunctional detection device | |
| CN205352943U (en) | Fluorescence detector | |
| CN214896684U (en) | Novel parking space detection video pile | |
| CN219799243U (en) | Portable fluorescence tester | |
| CN216747410U (en) | Fluorescence immunoassay quantitative analyzer | |
| CN205982094U (en) | Food safety inspection device based on intelligent Mobile Terminal | |
| CN218825552U (en) | Intelligent electronic student identity card with temperature measurement function | |
| CN218103364U (en) | Intelligent meter reading device, automatic meter reading device and related system | |
| CN219455948U (en) | Portable fluorescent probe solution visual detection device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |