CN211292848U

CN211292848U - Tester for continuously testing multiple groups of dissolution rates

Info

Publication number: CN211292848U
Application number: CN201922258377.8U
Authority: CN
Inventors: 刘洪波
Original assignee: Hinoldon Tianjin Technology Co ltd
Current assignee: Hinoldon Tianjin Technology Co ltd
Priority date: 2019-12-17
Filing date: 2019-12-17
Publication date: 2020-08-18
Anticipated expiration: 2029-12-17

Abstract

The utility model discloses a tester for continuously measuring multiple groups of dissolution rates, which relates to the technical field of dissolution rate measurement, and comprises a measuring machine body, wherein a base is fixedly arranged at the bottom end of the measuring machine body, a positioning cup disc is arranged between the measuring machine body and the base, a liquid storage cup is arranged at the inner side of the positioning cup disc, a telescopic rod is fixedly connected between the base and the positioning cup disc, a lifting rod is fixedly connected at the bottom end of the positioning cup disc, a fixed loop rod is movably sleeved at the outer side of the bottom end of the lifting rod, a limiting chute is arranged on the inner side surface of the fixed loop rod, and the telescopic rod, an assembly ring, a positioning column, the positioning cup disc, an assembly groove, a positioning groove, a lifting rod, a fixed loop rod, a limiting chute, a connecting screw hole, a locking screw rod, a positioning slider and a locking screw hole are arranged on the positioning cup disc, so that the installation and the disassembly, the cleaning treatment of the liquid storage cup at the later stage is convenient.

Description

Tester for continuously testing multiple groups of dissolution rates

Technical Field

The utility model relates to a degree of dissolving out survey technical field specifically is a survey multiunit degree of dissolving out tester in succession.

Background

Dissolution rate: refers to the rate and extent of dissolution of a drug from a solid preparation such as a tablet in a predetermined solvent. Dissolution rate is an important index for controlling the quality of tablets, and the dissolution rate of insoluble medicines is generally checked. In the preparation for checking the dissolution rate, the check of disintegration time limit is not carried out, most oral solid preparations are effective after being absorbed into blood circulation after being administrated, and a certain blood concentration is achieved, so that the drug is released from the preparation and dissolved in body fluid under the premise that the drug is absorbed, the process is called dissolution in biomedicine, the dissolution speed and degree are called dissolution, from the perspective of drug inspection, the dissolution refers to the speed and degree of dissolution of the drug from a solid preparation such as a tablet or a capsule in a specified solvent, the absorption speed of the drug in vivo is often determined by the speed of dissolution, the drug in the solid preparation must be disintegrated and dissolved before being absorbed, and then the drug in the solid preparation is converted into a solution, if the drug is not easily released from the preparation or the dissolution speed of the drug is extremely slow, the absorption speed or degree of the drug in the preparation can have problems, on the other hand, if the dissolution speed of some medicines with violent pharmacological action and small safety index and quick absorption is too fast, obvious adverse reaction can be generated, and the time for maintaining the medicine effect is shortened.

However, in the using process of the traditional tester for continuously measuring multiple groups of dissolution rates, because the liquid storage cup is difficult to mount and dismount on the tester body, the mounting and dismounting working efficiency of the liquid storage cup is low, and the inconvenience is brought to the cleaning treatment of the liquid storage cup in the later period, therefore, the technical personnel in the field provide the tester for continuously measuring multiple groups of dissolution rates.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a survey multiunit degree of dissolution apparatus in succession to propose the tradition in solving above-mentioned background art and survey multiunit degree of dissolution apparatus in succession in the use, owing to deposit the liquid cup and be difficult to the installation dismantlement on survey organism, the work efficiency of depositing the installation dismantlement of liquid cup is lower, washs the problem of handling inconvenience to depositing the liquid cup for the later stage.

In order to achieve the above object, the utility model provides a following technical scheme:

a tester for continuously testing multiple groups of dissolution rates comprises a testing machine body, a base is fixedly arranged at the bottom end of the testing machine body, a positioning cup tray is arranged between the measuring machine body and the base, a liquid storage cup is arranged at the inner side of the positioning cup tray, a telescopic rod is fixedly connected between the base and the positioning cup tray, a lifting rod is fixedly connected at the bottom end of the positioning cup tray, a fixed loop bar is movably sleeved outside the bottom end of the lifting bar, a limit chute is arranged on the inner side surface of the fixed loop bar, a positioning slide block is fixedly arranged on the side surface of the bottom end of the lifting rod, a locking screw hole is arranged on the side surface of the positioning slide block, the side surface of the upper end of the fixed loop bar is provided with a connecting screw hole, the connecting screw hole and the locking screw hole are in threaded connection with a locking screw rod, an assembly ring is fixedly arranged at the upper end of the liquid storage cup, and an assembly groove is formed in the position of the surface of the upper end of the positioning cup disc.

As a further aspect of the present invention: the bottom end of the fixed loop bar is fixedly connected with the base, and the positioning sliding block is connected with the limiting sliding groove in a sliding mode.

As a further aspect of the present invention: a cup receiving chassis is arranged at the position, right below the positioning cup tray, of the inner side of the base, and a spring is fixedly connected between the base and the cup receiving chassis.

As a further aspect of the present invention: a buffer pad is fixedly arranged on the surface of the upper end of the cup receiving chassis, and the buffer pad is a rubber component.

As a further aspect of the present invention: the bottom surface of the assembling ring is fixedly provided with a positioning column, a positioning groove is formed in the position, corresponding to the positioning column, of the inner side surface of the assembling groove, the cross sections of the positioning column and the positioning groove are rectangular, and the size of the positioning column is matched with that of the positioning groove.

As a further aspect of the present invention: the inner side position of the measuring machine body is provided with a stirring shaft, the bottom end of the stirring shaft is fixedly provided with a stirring blade, and one end position of the locking screw rod is fixedly provided with a rotating handle.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the utility model discloses telescopic link, assembly ring, reference column, location cup dish, assembly groove, positioning groove, lifter, fixed loop bar, spacing spout, connection screw, locking screw, location slider and locking screw have been set up for deposit the liquid cup and install and dismantle more convenient simple on location cup dish, be favorable to improving the work efficiency of depositing liquid cup installation dismantlement, the later stage of being convenient for is to depositing liquid cup cleaning process.

2. The utility model discloses set up and connect cup chassis, spring and blotter, the elasticity that the spring produced can play good buffering guard action to depositing the liquid cup, the phenomenon of taking place the damage easily when preventing to deposit the liquid cup dismantlement effectively.

Drawings

FIG. 1 is a schematic perspective view of a continuous dissolution tester for multiple groups;

FIG. 2 is a schematic diagram of a front view of a dissolution tester for continuously measuring multiple groups of dissolution rates;

FIG. 3 is an enlarged schematic view of portion A of a dissolution tester for continuously measuring multiple groups of dissolution rates;

fig. 4 is an enlarged structural view of part B of a dissolution tester for continuously measuring a plurality of groups.

In the figure: 1. measuring the organism; 2. a base; 3. a telescopic rod; 4. a liquid storage cup; 401. assembling a ring; 402. a positioning column; 5. positioning a cup and a tray; 501. assembling a groove; 502. a positioning groove; 6. a stirring shaft; 601. stirring blades; 7. a lifting rod; 8. fixing the loop bar; 801. a limiting chute; 802. a connecting screw hole; 9. a cup receiving chassis; 10. a spring; 12. a cushion pad; 13. locking the screw rod; 14. positioning the sliding block; 141. and locking the screw hole.

Detailed Description

Referring to fig. 1-4, in the embodiment of the present invention, a multi-group dissolution rate continuous measurement apparatus comprises a measurement apparatus body 1, a base 2 is fixedly disposed at the bottom end of the measurement apparatus body 1, a positioning cup 5 is disposed between the measurement apparatus body 1 and the base 2, a liquid storage cup 4 is disposed at the inner side of the positioning cup 5, a telescopic rod 3 is fixedly connected between the base 2 and the positioning cup 5, a lifting rod 7 is fixedly connected at the bottom end of the positioning cup 5, a fixing loop rod 8 is movably sleeved at the outer side of the bottom end of the lifting rod 7, a limiting chute 801 is disposed on the inner side surface of the fixing loop rod 8, a positioning slider 14 is fixedly disposed at the bottom end side of the lifting rod 7, a locking screw hole 141 is disposed at the side surface of the positioning slider 14, a connecting screw hole 802 is disposed at the upper end side surface of the fixing loop rod 8, a locking screw 13 is threadedly connected with the connecting, the upper end surface of the positioning cup tray 5 is provided with an assembling groove 501.

In fig. 1 and 3: the bottom end of the fixed loop bar 8 is fixedly connected with the base 2, and the positioning sliding block 14 is connected with the limiting sliding groove 801 in a sliding manner, so that the purpose that the lifting rod 7 can move on the fixed loop bar 8 along the limiting sliding groove 801 is achieved.

In fig. 2: the inboard position department that is located location cup dish 5 of base 2 is provided with and connects cup chassis 9, base 2 with connect fixedly connected with spring 10 between the cup chassis 9, connect the fixed blotter 12 that is provided with of upper end surface position department of cup chassis 9, blotter 12 is a material for the component of rubber, has reached and has played the purpose of good buffering guard action to depositing liquid cup 4.

In fig. 4: the bottom end surface of the assembling ring 401 is fixedly provided with a positioning column 402, the inner side surface of the assembling groove 501 and the position corresponding to the positioning column 402 are provided with a positioning groove 502, the cross sections of the positioning column 402 and the positioning groove 502 are rectangular, the size of the positioning column 402 is matched with the size of the positioning groove 502, and the purpose that the positioning column 402 can be matched and inserted in the positioning groove 502 is achieved.

In fig. 2: the inside position department of survey organism 1 is provided with (mixing) shaft 6, and the bottom mounting of (mixing) shaft 6 is provided with stirring leaf 601, and locking screw 13's one end position department is fixed and is provided with the twist grip, has reached the purpose of being convenient for rotate locking screw 13.

The utility model discloses a theory of operation is: in using this degree of dissolution apparatus in-process, when needs wash the processing to depositing liquid cup 4, loosen locking screw 13, can be on fixed loop bar 8 along spacing spout 801 activity downwards with lifter 7, thereby make location cup dish 5 descend, deposit liquid cup 4 on the location cup dish 5 descends to connecing cup chassis 9, base 2 with connect fixedly connected with spring 10 between the cup chassis 9, the elasticity that spring 10 produced can play good buffering guard action to depositing liquid cup 4, then will deposit liquid cup 4 upwards take out the cleaning process go on, deposit liquid cup 4 after the cleaning process arranges in on location cup dish 5, can upwards move about along spacing spout 801 on fixed loop bar 8 with lifter 7, it can through connecting screw 802 and locking screw 141 fixed connection to use locking screw 13.

The above-mentioned, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.

Claims

1. The tester for continuously measuring multiple groups of dissolution rates comprises a tester body (1) and is characterized in that a base (2) is fixedly arranged at the bottom end of the tester body (1), a positioning cup disc (5) is arranged between the tester body (1) and the base (2), a liquid storage cup (4) is arranged on the inner side of the positioning cup disc (5), a telescopic rod (3) is fixedly connected between the base (2) and the positioning cup disc (5), a lifting rod (7) is fixedly connected at the bottom end of the positioning cup disc (5), a fixed loop bar (8) is movably sleeved at the outer side of the bottom end of the lifting rod (7), a limiting sliding groove (801) is formed in the inner side surface of the fixed loop bar (8), a positioning sliding block (14) is fixedly arranged on the side surface of the bottom end of the lifting rod (7), and a locking screw hole (141) is formed in the side surface of the positioning sliding, the connecting screw hole (802) has been seted up to the upper end side of fixed loop bar (8), connecting screw hole (802) and locking screw hole (141) threaded connection have locking screw (13), the fixed assembly ring (401) that is provided with in upper end of depositing liquid cup (4), assembly groove (501) have been seted up to the upper end surface position department of location cup dish (5).

2. The dissolution tester of claim 1, wherein the bottom end of the fixed loop bar (8) is fixedly connected to the base (2), and the positioning slider (14) is slidably connected to the position-limiting sliding groove (801).

3. The dissolution tester of claim 1, wherein a cup receiving chassis (9) is disposed at a position right below the positioning cup tray (5) inside the base (2), and a spring (10) is fixedly connected between the base (2) and the cup receiving chassis (9).

4. A dissolution tester according to claim 3, wherein a buffer pad (12) is fixed to the cup receiving chassis (9) at a position on the upper end surface thereof, and the buffer pad (12) is a rubber member.

5. The dissolution tester of claim 1, wherein a positioning post (402) is fixedly disposed on a bottom surface of the assembling ring (401), a positioning groove (502) is formed in a position of an inner side surface of the assembling groove (501) corresponding to the positioning post (402), cross-sectional shapes of the positioning post (402) and the positioning groove (502) are both rectangular, and a size of the positioning post (402) is matched with a size of the positioning groove (502).

6. The dissolution tester of claim 1, wherein a stirring shaft (6) is disposed at an inner side of the tester body (1), a stirring blade (601) is fixedly disposed at a bottom end of the stirring shaft (6), and a rotating handle is fixedly disposed at one end of the locking screw (13).