CN211292847U

CN211292847U - Novel dissolution rate tester

Info

Publication number: CN211292847U
Application number: CN201922254337.6U
Authority: CN
Inventors: 刘洪波
Original assignee: Hinoldon Tianjin Technology Co ltd
Current assignee: Hinoldon Tianjin Technology Co ltd
Priority date: 2019-12-16
Filing date: 2019-12-16
Publication date: 2020-08-18
Anticipated expiration: 2029-12-16

Abstract

The utility model discloses a novel dissolution tester, relating to the technical field of dissolution testing, which comprises a testing machine body and a stirring shaft arranged at the inner side of the testing machine body, an assembly shaft is arranged at the bottom side of the stirring shaft, a stirring paddle is fixedly arranged at the bottom end of the assembly shaft, an assembly cavity is arranged on the inner side surface of the bottom end of the stirring shaft, a telescopic rod is fixedly arranged on the side surface of the upper end of the assembly shaft, one end of the telescopic rod is fixedly connected with a positioning block, a spring is fixedly connected between the positioning block and the assembling shaft, the inner side surface of the assembly cavity is provided with a limit chute, the utility model is provided with an assembly shaft, an assembly cavity, a limit chute, a positioning through hole, a positioning block, a telescopic rod and a spring, the stirring paddle is convenient and simple to mount and dismount on the stirring shaft, the stirring paddle is convenient to replace or clean and maintain regularly, and the working efficiency of stirring paddle replacement or cleaning and maintaining treatment is improved.

Description

Novel dissolution rate tester

Technical Field

The utility model relates to a degree of dissolving out survey technical field specifically is a novel degree of dissolving out apparatus.

Background

Dissolution rate: refers to the rate and extent of dissolution of a drug from a solid preparation such as a tablet in a predetermined solvent. Dissolution rate is an important index for controlling the quality of tablets, and the dissolution rate of insoluble medicines is generally checked. In the preparation for checking the dissolution rate, the check of disintegration time limit is not carried out, most oral solid preparations are effective after being absorbed into blood circulation after being administrated, and a certain blood concentration is achieved, so that the drug is released from the preparation and dissolved in body fluid under the premise that the drug is absorbed, the process is called dissolution in biomedicine, the dissolution speed and degree are called dissolution, from the perspective of drug inspection, the dissolution refers to the speed and degree of dissolution of the drug from a solid preparation such as a tablet or a capsule in a specified solvent, the absorption speed of the drug in vivo is often determined by the speed of dissolution, the drug in the solid preparation must be disintegrated and dissolved before being absorbed, and then the drug in the solid preparation is converted into a solution, if the drug is not easily released from the preparation or the dissolution speed of the drug is extremely slow, the absorption speed or degree of the drug in the preparation can have problems, on the other hand, some drugs with severe pharmacological action, small safety index and rapid absorption may cause obvious adverse reaction if the dissolution speed is too fast, and the time for maintaining the drug effect is also shortened.

However, in the use process of the traditional dissolution tester, the stirring paddle is difficult to mount and dismount on the stirring shaft, so that inconvenience is brought to regular replacement or cleaning maintenance of the stirring paddle, and the working efficiency of replacement or cleaning maintenance of the stirring paddle is reduced, so that technical personnel in the field provide a novel dissolution tester.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a novel degree of dissolving out apparatus to propose traditional degree of dissolving out apparatus in the use among the above-mentioned background art of solution, because the stirring rake is installed on the (mixing) shaft and is dismantled comparatively difficultly, lead to regularly changing or the clean maintenance is handled and is brought inconvenience to the stirring rake, reduced the stirring rake and changed or the problem of the work efficiency of clean maintenance processing.

In order to achieve the above object, the utility model provides a following technical scheme:

a novel dissolution tester comprises a tester body and a stirring shaft arranged at the inner side of the tester body, wherein the bottom side of the stirring shaft is provided with an assembling shaft, the bottom end of the assembling shaft is fixedly provided with a stirring paddle, the inner side surface of the bottom end of the stirring shaft is provided with an assembling cavity, the upper end side surface of the assembling shaft is fixedly provided with a telescopic rod, one end of the telescopic rod is fixedly connected with a positioning block, a spring is fixedly connected between the positioning block and the assembling shaft, the inner side surface of the assembling cavity is provided with a limiting sliding chute, the side surface of the stirring shaft close to one side position of the limiting sliding chute is provided with a positioning through hole, the bottom end of the tester body is fixedly provided with a fixing frame, the bottom end of the fixing frame is fixedly provided with a fixing base, the surface of the fixing base is fixedly provided, the side of the positioning seat is provided with an adjusting screw hole, the adjusting screw hole is in threaded connection with a locking screw rod, and a supporting bottom plate is fixedly arranged at the bottom end of the fixing base.

As a further aspect of the present invention: the diameter size of the assembly shaft is matched with the inner diameter size of the assembly cavity, and the positioning block is connected with the limiting sliding groove in a sliding mode.

As a further aspect of the present invention: the spring is movably sleeved outside the telescopic rod, and the caliber size of the positioning through hole is matched with the section size of the positioning block.

As a further aspect of the present invention: the side surface of the cup seat is provided with a positioning hole, and the diameter size of the rod of the locking screw is matched with the diameter size of the positioning hole.

As a further aspect of the present invention: and one end of the locking screw rod is fixedly provided with an adjusting handle, and the cross section of the adjusting handle is in a regular hexagon shape.

As a further aspect of the present invention: the bottom surface of supporting baseplate department is fixed and is provided with the abrasion pad, the abrasion pad is the component that a material is rubber, the bottom surface of abrasion pad has seted up anti-skidding recess.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the utility model discloses assembly axle, assembly chamber, spacing spout, location opening, locating piece, telescopic link and spring have been set up for the stirring rake is installed on the (mixing) shaft and is dismantled convenient simple, is convenient for regularly change or clean maintenance processing to the stirring rake, is favorable to improving the work efficiency that the stirring rake was changed or clean maintenance was handled.

2. The utility model discloses set up cup, locating hole, mount, positioning seat and regulation screw, can carry out quick location with the cup and place, the simple operation is simple, and the convenient to use personnel use more.

Drawings

FIG. 1 is a schematic perspective view of a novel dissolution tester;

FIG. 2 is a schematic diagram of a novel dissolution tester in elevation;

FIG. 3 is an enlarged schematic view of part A of a novel dissolution tester.

In the figure: 1. measuring the organism; 2. a cup holder; 201. positioning holes; 3. a fixed mount; 4. positioning seats; 401. adjusting the screw hole; 5. a support base plate; 501. a wear pad; 502. an anti-slip groove; 6. a fixed base; 7. a liquid storage cup; 8. assembling a shaft; 9. a stirring shaft; 901. an assembly chamber; 902. a limiting chute; 903. positioning the through opening; 10. locking the screw rod; 11. an adjusting handle; 12. positioning blocks; 13. a telescopic rod; 14. a spring; 15. and (4) a stirring paddle.

Detailed Description

Referring to fig. 1-3, in the embodiment of the present invention, a novel dissolution tester comprises a testing machine body 1 and a stirring shaft 9 disposed inside the testing machine body 1, wherein an assembling shaft 8 is disposed at the bottom side of the stirring shaft 9, a stirring paddle 15 is disposed at the bottom end of the assembling shaft 8, an assembling cavity 901 is disposed on the inner side surface of the bottom end of the stirring shaft 9, an expansion link 13 is fixedly disposed at the upper end side of the assembling shaft 8, a positioning block 12 is fixedly connected to one end of the expansion link 13, a spring 14 is fixedly connected between the positioning block 12 and the assembling shaft 8, a limiting chute 902 is disposed on the inner side surface of the assembling cavity 901, a positioning through hole 903 is disposed at a position on the side of the stirring shaft 9 close to the limiting chute 902, a fixing frame 3 is disposed at the bottom end of the testing machine body 1, a fixing base, the inboard of positioning seat 4 is provided with cup 2, and the inboard of cup 2 is provided with deposits liquid cup 7, and regulation screw 401 has been seted up to the side of positioning seat 4, and regulation screw 401 threaded connection has locking screw 10, and unable adjustment base 6's bottom mounting is provided with supporting baseplate 5.

In fig. 3: the diameter size of the assembly shaft 8 is matched with the inner diameter size of the assembly cavity 901, and the positioning block 12 is in sliding connection with the limiting sliding groove 902, so that the purpose that the positioning block 12 can slide along the limiting sliding groove 902 in a limiting manner is achieved.

In fig. 3: spring 14 activity cup joints in the outside of telescopic link 13, and the bore size of location through-hole 903 and the cross-sectional dimension looks adaptation of locating piece 12 have reached the elasticity that spring 14 compression deformation produced and can extrude locating piece 12 to the inboard purpose of location through-hole 903.

In fig. 2: the side position of the cup base 2 is provided with a positioning hole 201, and the rod diameter size of the locking screw 10 is matched with the diameter size of the positioning hole 201, so that the locking screw 10 can be inserted into the positioning hole 201.

In fig. 1 and 2: the fixed adjustment handle 11 that is provided with of one end of locking screw 10, adjustment handle 11's cross sectional shape is regular hexagon, and the fixed antifriction pad 501 that is provided with of bottom surface position department of supporting baseplate 5, antifriction pad 501 are the component that the material is rubber, and anti-skidding recess 502 has been seted up to the bottom surface of antifriction pad 501, has reached the purpose that improves supporting baseplate 5 anti-skidding performance.

The utility model discloses a theory of operation is: in the process of using the dissolution tester, when the stirring paddle 15 needs to be replaced or cleaned and maintained, the positioning block 12 is pressed to enable the stirring paddle 15 to enter the limiting sliding groove 902 through the positioning through hole 903, the positioning block 12 is in sliding connection with the limiting sliding groove 902, the assembling shaft 8 is drawn out of the assembling cavity 901, at the moment, the stirring paddle 15 can be disassembled to be replaced or cleaned and maintained, when the stirring paddle 15 needs to be installed, the positioning block 12 is pressed to enable the positioning block 12 to slide towards the inner side of the assembling cavity 901 along the limiting sliding groove 902, when the positioning block 12 moves to the positioning through hole 903, the elastic force generated by compression deformation of the spring 14 can extrude the positioning block 12 to the inner side of the positioning through hole 903, and therefore the stirring paddle 15 can be quickly positioned and installed on the stirring shaft.

The above-mentioned, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.

Claims

1. A novel dissolution tester comprises a testing machine body (1) and a stirring shaft (9) arranged on the inner side of the testing machine body (1), and is characterized in that an assembly shaft (8) is arranged on the bottom side of the stirring shaft (9), a stirring paddle (15) is fixedly arranged at the bottom end of the assembly shaft (8), an assembly cavity (901) is formed in the inner side surface of the bottom end of the stirring shaft (9), an expansion link (13) is fixedly arranged on the side surface of the upper end of the assembly shaft (8), a positioning block (12) is fixedly connected to one end of the expansion link (13), a spring (14) is fixedly connected between the positioning block (12) and the assembly shaft (8), a limiting sliding groove (902) is formed in the inner side surface of the assembly cavity (901), a positioning through hole (903) is formed in the position, close to the limiting sliding groove (902), of the side surface of the stirring shaft (9), a fixing frame (, the bottom mounting of mount (3) is provided with unable adjustment base (6), the fixed surface of unable adjustment base (6) is provided with positioning seat (4), the inboard of positioning seat (4) is provided with cup (2), the inboard of cup (2) is provided with deposits liquid cup (7), regulation screw (401) have been seted up to the side of positioning seat (4), regulation screw (401) threaded connection has locking screw (10), the bottom mounting of unable adjustment base (6) is provided with supporting baseplate (5).

2. The dissolution tester according to claim 1, wherein the diameter of the assembling shaft (8) is adapted to the inner diameter of the assembling cavity (901), and the positioning block (12) is slidably connected to the limiting sliding groove (902).

3. The new dissolution tester according to claim 1, wherein the spring (14) is movably sleeved outside the telescopic rod (13), and the caliber size of the positioning through hole (903) is matched with the section size of the positioning block (12).

4. The novel dissolution tester according to claim 1, wherein a positioning hole (201) is formed at a side position of the cup holder (2), and the diameter of the locking screw (10) is matched with the diameter of the positioning hole (201).

5. The new dissolution tester according to claim 1, wherein an adjusting handle (11) is fixedly arranged at one end of the locking screw (10), and the cross-sectional shape of the adjusting handle (11) is regular hexagon.

6. The new dissolution tester according to claim 1, wherein a wear pad (501) is fixedly disposed at the bottom surface of the supporting bottom plate (5), the wear pad (501) is a rubber member, and the bottom surface of the wear pad (501) is provided with an anti-slip groove (502).