CN211122192U - Integrative cellular-type tissue dehydration embedding box - Google Patents
Integrative cellular-type tissue dehydration embedding box Download PDFInfo
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- CN211122192U CN211122192U CN201921641570.3U CN201921641570U CN211122192U CN 211122192 U CN211122192 U CN 211122192U CN 201921641570 U CN201921641570 U CN 201921641570U CN 211122192 U CN211122192 U CN 211122192U
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- dehydration
- cover plate
- tissue
- embedding box
- upper cover
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- 230000018044 dehydration Effects 0.000 title claims abstract description 95
- 238000006297 dehydration reaction Methods 0.000 title claims abstract description 95
- 239000012188 paraffin wax Substances 0.000 claims description 25
- 238000000926 separation method Methods 0.000 claims description 20
- 238000003860 storage Methods 0.000 claims description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 238000005728 strengthening Methods 0.000 claims description 6
- 230000008520 organization Effects 0.000 claims 1
- 239000000463 material Substances 0.000 abstract description 10
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 4
- 238000004043 dyeing Methods 0.000 abstract description 3
- 230000000694 effects Effects 0.000 abstract description 3
- 239000011521 glass Substances 0.000 abstract description 2
- 210000001519 tissue Anatomy 0.000 description 55
- 238000000034 method Methods 0.000 description 13
- 229940057995 liquid paraffin Drugs 0.000 description 8
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 239000011324 bead Substances 0.000 description 3
- 230000003014 reinforcing effect Effects 0.000 description 3
- 230000001413 cellular effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000001993 wax Substances 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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Abstract
The utility model discloses an integrative cellular-type tissue dehydration embedding box, including dehydration embedding box structure, dehydration embedding box structure top activity is provided with upper portion cover plate structure, its the bottom joint of dehydration embedding box structure has lower part tray structure, dehydration embedding box structure, upper portion cover plate structure and lower part tray structure three be the integrative structure of combination formula, and this integrative cellular-type tissue dehydration embedding box when dehydrating the embedding to the tissue that has many parts to draw materials, can reduce the use amount of dehydration box, dehydration and dyeing reagent and slide glass in a large number, practiced thrift the consumptive material cost.
Description
Technical Field
The utility model relates to a medical treatment detecting instrument technical field specifically is an integrative cellular-type tissue dehydration embedding box.
Background
Tissue dehydration cassettes are consumable materials commonly used in the production of biological tissue slides. The tissue obtained by the material-obtaining person is respectively put into corresponding dehydration boxes for dehydration, is transparent and is soaked in wax, and then the tissue is embedded by the wax to be made into paraffin blocks for slicing.
Aiming at the existing tissue dehydration embedding process, firstly, printing the serial number and the part number of the tissue to be taken out on a dehydration box, and recording the part corresponding to the part number on a material taking sheet; secondly, taking materials of the tissues fixed by formaldehyde according to the required requirements and placing the tissues into corresponding dehydration boxes, wherein the tissues at different parts need to be placed in different dehydration boxes respectively; thirdly, placing the dewatering box with the tissue into a dewatering machine for dewatering; fourthly, after the dehydration is finished, taking the dehydration box out of the dehydrator, opening a box cover of the dehydration box and discarding the box cover, and horizontally placing a box body of the dehydration box on an embedding machine; fifthly, clamping the tissues in the box body of the dehydration box by using forceps and transferring the tissues to an embedding bottom box; sixthly, injecting liquid paraffin into the embedding bottom box, and then placing the box body of the dehydration box with the tissue number on the paraffin; seventhly, continuously injecting liquid paraffin into the box body, and integrating the box body and the paraffin block into a whole; eighthly, after the paraffin is solidified, separating the paraffin block from the embedding bottom box, and finishing the preparation of the tissue paraffin block; and step nine, placing the tissue paraffin block on a slicer, slicing the tissue paraffin block, dyeing, and finally manufacturing a dyed tissue slide.
The process can be seen that the tissue dehydration embedding process is more complicated and is easy to make mistakes, and the usage amount of the dehydration box as a disposable consumable is extremely large. Therefore, how to simplify the dehydration embedding procedure, improve the working quality and efficiency, reduce the use amount of the dehydration box and the corresponding reagent and consumable materials is a problem which needs to be solved urgently at present. To this end, we propose an integrally partitioned tissue dehydration embedding cassette.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an integrative cellular-type tissue dehydration embedding box to solve the problem that proposes among the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides an integrative cellular-type tissue dehydration embedding box, includes dehydration embedding box structure, dehydration embedding box structure top activity is provided with upper cover plate structure, its the bottom joint of dehydration embedding box structure has lower part tray structure, dehydration embedding box structure, upper cover plate structure and lower part tray structure three are integrative structure of combination formula.
The three-section combined integrated structure comprises a dehydration embedding box structure, an upper cover plate structure and a lower tray structure, and the three parts are mutually buckled together without manual connection in the use process.
Preferably, the dehydration embedding box structure comprises a dehydration embedding box main body with a dehydration drum, a reinforcing rib is fixed in a frame on one side of the dehydration embedding box main body, an information printing plate is fixed on one side, away from the dehydration embedding box main body, of the reinforcing rib, and a locking hole is formed in the dehydration embedding box main body between the two groups of reinforcing ribs.
Preferably, the upper portion apron structure includes the upper portion apron main part, one side of upper portion apron main part is provided with the articulated shaft, just one side of upper portion apron is passed through the articulated shaft with the dehydration embedding box is articulated, the upper portion apron top is kept away from articulated shaft side one side is fixed with the upper portion and draws the handle, the upper portion apron bottom is close to one side that the handle was drawn to upper portion is fixed with the upper portion hasp, the bottom of upper portion apron is passed through the joint of upper portion hasp is in on the top of dehydration embedding box main part, the bottom of upper portion apron is provided with intercrossing's upper portion parting bead, the bottom of upper portion apron by the upper portion parting bead falls into six regions, and in six regions seted up a plurality of holes of permeating water on the upper portion apron, the top of upper portion apron body has been. The upper separation strips in the upper cover plate main body and the storage grid separation strips in the lower tray are designed, and after the upper cover plate main body is closed, the upper separation strips of the upper cover plate main body are completely meshed with the storage grid separation strips in the lower tray, so that tissues are prevented from overflowing out of the tissue storage grids; the separation mark of the upper cover plate is designed to be used as a main frame surface positioning mark of the paraffin block.
Preferably, the diameter of the water permeable holes is 0.5 mm.
Preferably, a paraffin fixing rib is fixed at the bottom of the upper separation strip. The fixed muscle design of wave type paraffin of upper portion apron main part ensures that the paraffin piece after solidifying fuses as an organic whole with dehydration embedding box main part and upper portion apron main part to possess sufficient mechanical strength, wave type structure ensures that dehydration in-process reagent can be smoothly from the intermittent type outflow of wave type.
Preferably, the paraffin fixing rib is in a wave shape.
Preferably, lower part tray structure includes lower part tray main part, the both sides of upper portion tray are fixed with first lower part pull handle and second lower part pull handle respectively, and first lower part pull handle and second lower part pull handle are corresponding be fixed with first lower part hasp and second lower part hasp respectively on the upper portion tray, first lower part hasp passes the hasp mouth with dehydration embedding box main part lock joint, just second lower part hasp then with the lateral wall lock joint of dehydration embedding box opposite side, the inside of lower part tray main part is provided with the tissue and stores the check, the tissue stores the check and comprises storage check parting strip, just it divides into six regions with it to store the parting strip. The tissue storage grid design of the lower tray can place a plurality of tissues at different parts with the same number in the same dehydration embedding box for dehydration and embedding.
Preferably, one of the tissue storage compartments is provided with a tissue positioning ramp. The inclined plane design is organized to lower part tray, because the existence on inclined plane is organized to lower part tray, makes the upper left corner of paraffin piece tissue face have a triangle-shaped breach, paraffin piece tissue face location mark when can regard as the section.
Preferably, a lower tray partition mark is arranged inside the grid of each tissue storage grid.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the utility model discloses when dehydrating the embedding to the tissue that has many parts to draw materials, can reduce the use amount of dehydration box, dehydration and dyeing reagent and slide glass in a large number, practiced thrift the consumptive material cost.
2. The utility model discloses when drawing materials, directly put into the relevant position with the tissue, cover the upper portion lid can, need not to press the step that combines with dehydration box and embedding end box. In the whole dehydration embedding section process, the position of the tissue does not need to be moved, the container does not need to be replaced, and the upper cover plate does not need to be discarded during embedding, so that a plurality of operation steps are reduced, tissue omission or cross contamination accidents are avoided, and the work efficiency of technicians is improved.
3. The utility model discloses when the embedding, directly pour into liquid paraffin into dehydration embedding box in, cover the upper portion apron back of taking the parting bead, because the fixed action of the fixed muscle of wave type paraffin, ensure that the paraffin piece after solidifying fuses with dehydration embedding box main part and upper portion apron as an organic whole to possess sufficient mechanical strength. The step of secondary injection of the liquid paraffin is not needed, and the working efficiency of technicians is improved.
4. The utility model discloses a three-section integral type design, a technician just can independently accomplish the embedding work, has reduced laboratory personnel configuration to the responsibility division of accident has been made clear.
5. The utility model discloses when having the tissue that many parts were drawn materials to dewater the embedding, can reduce the quantity of embedding paraffin piece in a large number to further reduce sliced quantity, improved technician's work efficiency.
6. The utility model discloses when carrying out the embedding, avoided organizing the skew because of the group that the technician person made the reason to cause, the condition such as small group tissue fusion takes place, has reduced the possibility of missing the diagnosis.
Drawings
FIG. 1 is a schematic perspective view of the present invention;
FIG. 2 is a schematic view of the structure of FIG. 1 in another orientation;
FIG. 3 is a schematic view of the present invention in a partial cross-sectional view;
FIG. 4 is an enlarged view of the area A in FIG. 3;
FIG. 5 is an enlarged view of the area B in FIG. 3;
FIG. 6 is a partial cross-sectional structural view of FIG. 3;
FIG. 7 is a structural diagram of an upper cover plate;
FIG. 8 is a schematic view of the structure of FIG. 7 in another orientation;
FIG. 9 is a schematic structural view from above of the structure of the dehydrating and embedding box;
FIG. 10 is a schematic bottom view of the structure of the dehydration encapsulation box;
FIG. 11 is a schematic top view of the upper cover plate structure;
FIG. 12 is a top view of the lower tray structure;
FIG. 13 is a schematic view of the main section of the upper deck structure;
FIG. 14 is a schematic structural view of a main section of a dehydrating and embedding box structure;
FIG. 15 is a schematic view of a main section of a lower tray structure;
FIG. 16 is a schematic view of an integrated structure of the present invention;
fig. 17 is a schematic view of the operation structure of the first step of the present invention;
fig. 18 is a schematic view of the second step of the present invention;
fig. 19 is a schematic view of the operation structure of the third step of the present invention;
fig. 20 is a schematic view of the operation structure of the fourth step of the present invention;
fig. 21 is a schematic view of the operation structure of the fifth step of the present invention.
In the figure: 1-dehydrating the embedding box structure; 1.1-dehydrating the cassette body; 1.2-reinforcing ribs; 1.3-locking hole; 1.4-information printing plate; 2-upper cover plate structure; 2.1-upper cover plate body; 2.2-hinge axis; 2.3-water permeable holes; 2.4-paraffin wax fixing ribs; 2.5-upper dividing strip; 2.6-upper cover plate separation designation; 2.7-upper locking; 2.8-upper pull handle; 3-a lower tray structure; 3.1-lower tray body; 3.2-first lower part lock catch; 3.3-first lower pull handle; 3.4-tissue positioning bevel; 3.5-tissue storage grid; 3.6-reservoir separator strip; 3.7-lower tray division designation; 3.8-second lower part lock catch; 3.9-second lower pull handle; 4.1-treatment of tissue; 4.2-liquid paraffin.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1 to 21, the present invention provides a technical solution: the utility model provides an integrative cellular-type tissue dehydration embedding box, includes dehydration embedding box structure (1), dehydration embedding box structure (1) top activity is provided with upper portion apron structure (2), its the bottom joint of dehydration embedding box structure (1) has lower part tray structure (3), dehydration embedding box structure (1), upper portion apron structure (2) and lower part tray structure (3) three are the integrative structure of combination formula.
Dehydration embedding box structure (1) is including dehydration package dehydration embedding box main part (1.1), one side frame internal fixation of dehydration embedding box main part (1.1) has strengthening rib (1.2), keep away from strengthening rib (1.2) one side of dehydration embedding box main part (1.1) is fixed with information printing plate (1.4), and is two sets of between strengthening rib (1.2) the hasp hole (1.3) has been seted up on dehydration embedding box main part (1.1).
The upper cover plate structure (2) comprises an upper cover plate main body (2.1), one side of the upper cover plate main body (2.1) is provided with a hinged shaft, one side of the upper cover plate is hinged with the dehydration embedding box through the hinge shaft, one side of the top of the upper cover plate, which is far away from the hinge shaft, is fixed with an upper pull handle (2.8), an upper lock catch (2.7) is fixed at one side of the bottom of the upper cover plate close to the upper pull handle (2.8), the bottom of the upper cover plate is clamped on the top of the dehydration embedding box main body (1.1) through the upper lock catch (2.7), the bottom of the upper cover plate is provided with upper separation strips (2.5) which are crossed mutually, the bottom of the upper cover plate is divided into six areas by the upper separation strips (2.5), and a plurality of water permeable holes (2.3) are arranged on the upper cover plate in the six areas, and an upper cover plate separation label (2.6) is arranged at the top of the upper cover plate body.
The aperture of the water permeable holes (2.3) is 0.5 mm.
And paraffin fixing ribs (2.4) are fixed at the bottoms of the upper separation strips (2.5).
The paraffin fixing ribs (2.4) are in a wave shape.
Lower part tray structure (3) include lower part tray main part (3.1), the both sides of upper portion tray are fixed with first lower pull handle (3.3) and second lower pull handle (3.9) respectively, and first lower pull handle (3.3) and second lower pull handle (3.9) are corresponding be fixed with first lower part hasp (3.2) and second lower part hasp (3.8) on the upper portion tray respectively, first lower part hasp (3.2) pass the hasp mouth with dehydration embedding box main part (1.1) lock joint, just second lower part hasp (3.8) then with the lateral wall lock joint of dehydration embedding box opposite side, the inside of lower part tray main part (3.1) is provided with tissue storage check (3.5), tissue storage check (3.5) comprise storage check parting strip (3.6), just storage parting strip divides it into six regions.
One group of the tissue storage grids (3.5) is provided with a tissue positioning bevel (3.4).
And a lower tray separation mark (3.7) is arranged in the grid of each tissue storage grid (3.5).
The method comprises the specific steps of the utility model,
in the first step, as shown in fig. 17, the upper cover body of the dehydration embedding box main body printed with information on the information printing plate (1.4) of the integral separation type tissue dehydration embedding box is opened, and the corresponding tissue to be taken is placed in the tissue storage grid (3.5) corresponding to the lower tray.
And secondly, as shown in figure 18, the upper cover plate main body (2.1) is pressed downwards to move the upper lock catch (2.7), the box cover is closed, at the moment, the space between the upper separation strip (2.5) of the upper cover plate main body (2.1) and the storage grid separation strip (3.6) of the lower tray main body (3.1) is completely closed, and the integrated separated tissue dehydration embedding box with tissues (as shown in figure 16) is placed into a dehydrating machine for dehydration.
And thirdly, as shown in the attached figure 19, after the dehydration process is finished, taking out the integrated cellular tissue dehydration embedding box (shown as 16 in the attached figure), placing the integrated cellular tissue dehydration embedding box on an embedding machine, opening the upper cover plate main body (2.1), and directly injecting liquid paraffin (4.2).
Fourthly, as shown in figure 20, after the liquid paraffin (4.2) is filled, the upper cover plate body is closed and placed on a freezing table for cooling.
Fifthly, as shown in fig. 21, after the liquid paraffin (4.2) is solidified, the first lower pull handle (3.3) and the second lower pull handle (3.9) on the lower tray body are held by hands, the lower tray main body (3.1) is pulled out downwards, the paraffin block with the tissue is exposed (the side with the triangular notch is marked as 1), and the dehydration embedding box main body (1.1) is fixed on a paraffin block clamp of a slicer for slicing.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (9)
1. An integrative cellular-type tissue dehydration embedding box, includes dehydration embedding box structure (1), its characterized in that: the dehydration embedding box is characterized in that an upper cover plate structure (2) is movably arranged at the top of the dehydration embedding box structure (1), a lower tray structure (3) is clamped at the bottom of the dehydration embedding box structure (1), and the dehydration embedding box structure (1), the upper cover plate structure (2) and the lower tray structure (3) are of a combined type integrated structure.
2. The integrally partitioned tissue desiccating embedding cassette of claim 1, wherein: dehydration embedding box structure (1) is including dehydration embedding box main part (1.1), one side frame internal fixation of dehydration embedding box main part (1.1) has strengthening rib (1.2), keep away from strengthening rib (1.2) one side of dehydration embedding box main part (1.1) is fixed with information printing board (1.4), and is two sets of between strengthening rib (1.2) the hasp hole (1.3) has been seted up on dehydration embedding box main part (1.1).
3. The integrally partitioned tissue desiccating embedding cassette of claim 2, wherein: the upper cover plate structure (2) comprises an upper cover plate main body (2.1), one side of the upper cover plate main body (2.1) is provided with a hinged shaft, one side of the upper cover plate is hinged with the dehydration embedding box through the hinge shaft, one side of the top of the upper cover plate, which is far away from the hinge shaft, is fixed with an upper pull handle (2.8), an upper lock catch (2.7) is fixed at one side of the bottom of the upper cover plate close to the upper pull handle (2.8), the bottom of the upper cover plate is clamped on the top of the dehydration embedding box main body (1.1) through the upper lock catch (2.7), the bottom of the upper cover plate is provided with upper separation strips (2.5) which are crossed mutually, the bottom of the upper cover plate is divided into six areas by the upper separation strips (2.5), and a plurality of water permeable holes (2.3) are arranged on the upper cover plate in the six areas, and an upper cover plate separation label (2.6) is arranged at the top of the upper cover plate body.
4. The integrally partitioned tissue desiccating embedding cassette of claim 3, wherein said cassette comprises: the aperture of the water permeable holes (2.3) is 0.5 mm.
5. The integrally partitioned tissue desiccating embedding cassette of claim 3, wherein said cassette comprises: and paraffin fixing ribs (2.4) are fixed at the bottoms of the upper separation strips (2.5).
6. The integrally partitioned tissue desiccating embedding cassette of claim 5, wherein said cassette further comprises: the paraffin fixing ribs (2.4) are in a wave shape.
7. The integrally partitioned tissue desiccating embedding cassette of claim 2, wherein: the lower tray structure (3) comprises a lower tray main body (3.1), a first lower pull handle (3.3) and a second lower pull handle (3.9) are respectively fixed on two sides of the lower tray main body (3.1), and a first lower lock catch (3.2) and a second lower lock catch (3.8) are respectively fixed on the lower tray main body (3.1) corresponding to the first lower pull handle (3.3) and the second lower pull handle (3.9), the first lower lock catch (3.2) passes through the lock catch opening to be buckled with the dehydration embedding box main body (1.1), and the second lower lock catch (3.8) is buckled with the side wall at the other side of the dehydration embedding box main body (1.1), the lower tray main body (3.1) is internally provided with an organization storage grid (3.5), the tissue compartment (3.5) is formed by a compartment divider strip (3.6), and the compartment divider strip (3.6) divides it into six regions.
8. The integrally partitioned tissue desiccating embedding cassette of claim 7, wherein said cassette further comprises: one group of the tissue storage grids (3.5) is provided with a tissue positioning bevel (3.4).
9. The integrally partitioned tissue desiccating embedding cassette of claim 7, wherein said cassette further comprises: and a lower tray separation mark (3.7) is arranged in the grid of each tissue storage grid (3.5).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921641570.3U CN211122192U (en) | 2019-09-29 | 2019-09-29 | Integrative cellular-type tissue dehydration embedding box |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921641570.3U CN211122192U (en) | 2019-09-29 | 2019-09-29 | Integrative cellular-type tissue dehydration embedding box |
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| Publication Number | Publication Date |
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| CN211122192U true CN211122192U (en) | 2020-07-28 |
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| CN201921641570.3U Expired - Fee Related CN211122192U (en) | 2019-09-29 | 2019-09-29 | Integrative cellular-type tissue dehydration embedding box |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112161857A (en) * | 2020-10-16 | 2021-01-01 | 胡盛博 | Dehydration embedding box for human tissue specimen examination |
| CN113602634A (en) * | 2021-08-23 | 2021-11-05 | 江西金域医学检验所有限公司 | A set of pathological tissue inspection consumables |
| WO2023082079A1 (en) * | 2021-11-10 | 2023-05-19 | Leica Biosystems Nussloch Gmbh | Cassette and embedding method using same |
-
2019
- 2019-09-29 CN CN201921641570.3U patent/CN211122192U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112161857A (en) * | 2020-10-16 | 2021-01-01 | 胡盛博 | Dehydration embedding box for human tissue specimen examination |
| CN113602634A (en) * | 2021-08-23 | 2021-11-05 | 江西金域医学检验所有限公司 | A set of pathological tissue inspection consumables |
| WO2023082079A1 (en) * | 2021-11-10 | 2023-05-19 | Leica Biosystems Nussloch Gmbh | Cassette and embedding method using same |
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Granted publication date: 20200728 |