CN210972542U

CN210972542U - Sample precooling library plate structure for biological sample library choosing tube area

Info

Publication number: CN210972542U
Application number: CN201921561091.0U
Authority: CN
Inventors: 胡佳霖; 郑古成
Original assignee: Jidian Weike (chengdu) Medical Robot Technology Co ltd
Current assignee: Base Biotechnology (Chengdu) Co.,Ltd.
Priority date: 2019-09-19
Filing date: 2019-09-19
Publication date: 2020-07-10
Anticipated expiration: 2029-09-19

Abstract

The utility model discloses a sample precooling storehouse plate structure in a biological sample storehouse choosing tube area, which belongs to the technical field of biological sample storehouses and comprises a storehouse plate, an inner door and an outer door; the inner surface of the library plate facing to the biological sample library selecting pipe area and the outer surface of the library plate deviating from the biological sample library selecting pipe area are provided, the library plate is provided with a precooling cavity penetrating to the inner surface and the outer surface of the library plate, and a plurality of layers of sample box placing tables are arranged in the precooling cavity; the inner door and the outer door are respectively and correspondingly arranged at the positions of the precooling cavities on the inner surface and the outer surface of the storehouse plate so as to seal the precooling cavities. The functions of precooling, access port and closing door are integrated, the functions of access transfer, precooling and opening and closing are realized, the space is saved, and the efficiency is higher.

Description

Sample precooling library plate structure for biological sample library choosing tube area

Technical Field

The utility model belongs to the technical field of biological sample storehouse, concretely relates to sample precooling storehouse board structure in district under control is chosen to biological sample storehouse.

Background

Long-term storage of biological samples generally uses as low a temperature as possible to reduce biochemical reactions within the sample, improve the stability of various components within the sample, the lower the temperature, the longer the retention time of the sample. Generally, cryopreserved cells are placed in sample test tubes, the sample test tubes are placed on a storage rack through a sample box, and the storage rack is integrally placed in a refrigeration environment to realize long-term stable storage of samples.

Most of the prior art stores samples at low temperature by using a sample access device, and the number of the stored samples is relatively small. It is difficult to satisfy the requirement of centralized storage of a large number of biological samples in hospitals or research institutes and the like. Therefore, a sample library suitable for storing a large number of biological samples needs to be developed, and in the process of developing the sample library, a corresponding precooling structure needs to be designed to precool the external samples before storing the external samples.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a biological sample storehouse chooses sample precooling storehouse plate structure in district in area to solve external sample and deposit the precooling problem before.

For realizing the purpose of the utility model, the technical proposal adopted is that: a sample pre-cooling library plate structure for a biological sample library cantilever tube area comprises a library plate, an inner door and an outer door; the inner surface of the library plate facing to the biological sample library selecting pipe area and the outer surface of the library plate deviating from the biological sample library selecting pipe area are provided, the library plate is provided with a precooling cavity penetrating to the inner surface and the outer surface of the library plate, and a plurality of layers of sample box placing tables are arranged in the precooling cavity; the inner door and the outer door are respectively and correspondingly arranged at the positions of the precooling cavities on the inner surface and the outer surface of the storehouse plate so as to seal the precooling cavities.

As a further alternative, the sample box placing table comprises a placing plate fixed on the inner wall of the pre-cooling cavity and limiting strips fixed on two sides of the placing plate, and a sample box placing area is arranged between the two limiting strips.

As a further alternative, two ends of the opposite surfaces of the two limiting strips are provided with the guide inclined surfaces.

As a further alternative, the inner door comprises an inner door body for closing the pre-cooling cavity, two connecting rods respectively fixed at two ends of the inner door body, and two door opening devices respectively connected to the two connecting rods; the door opening devices comprise swing rods, inner door driving mechanisms for driving the swing rods to rotate, fixed guide rails parallel to the swing rods, and sliding blocks in sliding fit with the fixed guide rails, wherein one ends of connecting rods are hinged with the swing rods, and the other ends of the connecting rods are hinged with the sliding blocks; the inner door driving mechanism and the fixed guide rail are fixed on the inner surface of the warehouse board.

As the further alternative, the inner door body comprises an inner door plate, an inner door heat-insulation and heat-preservation plate and an inner door sealing strip, the inner door heat-insulation and heat-preservation plate is fixed on the surface, facing the pre-cooling cavity, of the inner door plate, and the inner door sealing strip is arranged around the inner door heat-insulation and heat-preservation plate.

As a further alternative, the outer door comprises an outer door body and an outer door driving mechanism for driving the outer door body to slide on the outer surface of the warehouse board; the outer door body includes slide plate, clamp plate and the clamp plate driving piece that the drive clamp plate removed to the precooling chamber, and the clamp plate driving piece is fixed in the slide plate.

As a further alternative, an outer door heat insulation board is fixed on the surface of the pressing board facing the pre-cooling cavity, and an outer door sealing strip located around the outer door heat insulation board is arranged on the pressing board.

As a further alternative, the pressing plate driving part comprises a pressing plate driving motor, a lead screw connected to the output end of the pressing plate driving motor, and a lead screw nut matched with the lead screw, the lead screw nut is fixedly connected with the pressing plate, and the pressing plate driving motor is fixed on the sliding plate.

The utility model has the advantages that: after the outer door is opened, putting a sample box with a sample outside on a sample box placing table in the pre-cooling cavity, and closing the outer door; after precooling, the inner door is opened, the sample box is taken out of the precooling cavity by a mechanical arm and other structures in the sample warehouse for subsequent operations such as tube picking and storage, and the inner door is closed. The precooling cavity is not only an access port for transferring samples inside and outside the sample warehouse, but also a precooling area, and the structure design of the sample warehouse plate integrates the functions of precooling, the access port and a sealing door, thereby realizing the functions of access transfer, precooling and opening and closing, saving the space and having higher efficiency.

Drawings

In order to more clearly illustrate the technical solution of the present invention, the drawings required for the description of the embodiments will be briefly introduced below, it should be understood that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.

Fig. 1 is an exploded view of a sample pre-cooling reservoir plate structure in a biological sample reservoir cantilever tube area according to an embodiment of the present invention;

fig. 2 is a top view of the pre-cooling chamber sample block positioning stage of fig. 1 in a state of positioning the sample block;

FIG. 3 is an exploded view of the inner door body of the inner door of FIG. 1;

FIG. 4 is a schematic view of the construction of the outer door of FIG. 1;

FIG. 5 is an exploded view of the outer door of FIG. 4;

reference numerals: 1. storing plates; 2. an inner door; 3. an outer door; 4. a pre-cooling chamber; 5. placing the plate; 6. a limiting strip; 7. an inner door body; 8. a connecting rod; 9. a swing rod; 10. fixing the guide rail; 11. a slider; 12. an inner door panel; 13. an inner door heat insulation board; 14. an inner door seal strip; 15. a fixed seat; 16. a driving gear; 17. a driven gear; 18. an outer door body; 19. a slide plate; 20. pressing a plate; 21. an outer door heat insulation board; 22. an outer door seal strip; 23. a lead screw; 24. a lead screw nut; 25. a gear; 26. a rack; 27. a sample cartridge.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention. It is to be understood that the drawings are designed solely for the purposes of illustration and description and not as a definition of the limits of the invention. The connection relationships shown in the drawings are for clarity of description only and do not limit the manner of connection.

It will be understood that when an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.

The present invention will be further described with reference to the accompanying drawings and specific embodiments.

Fig. 1 to 5 illustrate a sample pre-cooling library plate structure in a biological sample library cantilever area, which includes a library plate 1, an inner door 2 and an outer door 3; the inner surface of the library plate 1 facing to the biological sample library selecting pipe area and the outer surface of the library plate 1 deviating from the biological sample library selecting pipe area are provided, the library plate 1 is provided with a precooling cavity 4 penetrating to the inner surface and the outer surface of the library plate 1, and a plurality of layers of sample box placing tables are arranged in the precooling cavity 4; the inner door 2 and the outer door 3 are respectively and correspondingly arranged at the positions of the precooling cavities 4 on the inner surface and the outer surface of the storehouse plate 1 so as to seal the precooling cavities 4.

The sample box placing table comprises a placing plate 5 fixed on the inner wall of the pre-cooling cavity 4 and limiting strips 6 fixed on two sides of the placing plate 5, and a sample box placing area is arranged between the two limiting strips 6. Two sample cartridges 27 are illustrated. The sample box 27 is placed between the two position-limiting strips 6 on the placing plate 5. Both ends of the opposite surfaces of the two limiting strips 6 are provided with guide inclined surfaces, so that the guide function of taking and placing is achieved, and the sample box is convenient to put in and take out. The placing plate 5 can be opened with hollow holes to reduce the weight.

The inner door 2 comprises an inner door body 7 for sealing the pre-cooling cavity 4, two connecting rods 8 respectively fixed at two ends of the inner door body 7, and two door opening devices respectively connected to the two connecting rods 8; the door opening devices comprise swing rods 9, inner door driving mechanisms for driving the swing rods 9 to rotate, fixed guide rails 10 parallel to the swing rods 9 and sliders 11 matched with the fixed guide rails 10 in a sliding mode, one ends of connecting rods 8 are hinged with the swing rods 9, and the other ends of the connecting rods are hinged with the sliders 11; the inner door driving mechanism and the fixed rail 10 are fixed to the inner surface of the library panel 1. The swing rod 9 rotates to drive the connecting rod 8 to rotate relative to the swing rod 9, the other end of the connecting rod 8 rotates relative to the sliding block 11, and meanwhile, the sliding block 11 slides along the fixed guide rail 10, so that the inner door body 7 is opened and closed.

The inner door body 7 can comprise an inner door panel 12, an inner door heat insulation board 13 and an inner door sealing strip 14, wherein the inner door heat insulation board 13 is fixed on the surface of the inner door panel 12 facing the pre-cooling cavity 4, and the inner door sealing strip 14 is arranged around the inner door heat insulation board 13. The inner door panel 12 can be a metal plate, and the inner door heat insulation plate 13 can be a vacuum plate and can be bonded on the surface of the inner door panel 12, so that the good cold insulation and heat insulation effects are achieved.

When the refrigerator is closed, the swing rod 9 drives the inner door body 7 to move towards the pre-cooling cavity 4, the swing rod 9 has pressure on the inner door body 7 to enable the inner door body 7 to be close to the pre-cooling cavity 4, the inner door body 7 is pressed to the inner surface of the refrigerator board 1 on the periphery of the pre-cooling cavity 4, the inner door sealing strip 14 is also pressed on the periphery of the pre-cooling cavity 4, the sealing effect is good, the inner door heat insulation board 13 corresponds to the pre-cooling cavity 4, and the size of the inner door heat insulation board 13 is smaller than that of.

The inner door driving mechanism can comprise a fixed seat 15, a motor, a driving gear 16 and a driven gear 17 which are meshed with each other, wherein the driven gear 17 is rotatably supported on the fixed seat 15, the motor is fixed on the fixed seat 15, and the output end of the motor is connected with the driving gear 16; the swing rod 9 is fixedly connected with the driven gear 17. The motor and the driving gear 16 drive the driven gear 17 to rotate, the driven gear 17 drives the swing rod 9 to rotate, and other existing driving mechanisms such as motor direct drive, motor drive gear rack drive and the like can also be adopted.

The outer door 3 can comprise an outer door body 18 and an outer door driving mechanism for driving the outer door body 18 to slide on the outer surface of the warehouse board 1; the outer door body 18 comprises a sliding plate 19, a pressing plate 20 and a pressing plate driving piece for driving the pressing plate 20 to move towards the pre-cooling cavity 4, the pressing plate driving piece is fixed on the sliding plate 19, and therefore the sliding type structure is combined with the telescopic pressing type structure of the pressing plate 20, the occupied space for opening and closing the door is saved, and the outer door body has good sealing performance. An outer door heat insulation board 21 is fixed on the surface of the pressing board 20 facing the pre-cooling cavity 4, and an outer door sealing strip 22 located around the outer door heat insulation board 21 is arranged on the pressing board 20. When the door is closed, the sliding plate 19 moves to the position of the pre-cooling cavity 4, the pressure plate driving piece enables the pressure plate 20 to move towards the direction of the pre-cooling cavity 4, the outer door sealing strip 22 is enabled to be tightly pressed on the outer surface of the warehouse plate 1 around the pre-cooling cavity 4, and the pre-cooling cavity 4 is enabled to be closed; when the door is opened, the pressure plate driving piece enables the pressure plate 20 to retract from the pre-cooling cavity 4 and move to one side close to the sliding plate 19, and the sliding plate 19 and the pressure plate 20 move aside together to enable the pre-cooling cavity 4 to be opened. The outer door heat insulation board 21 corresponds to the pre-cooling cavity 4, and the size of the outer door heat insulation board 21 is smaller than that of the pre-cooling cavity 4. The slide plate 19 may be provided with a slide rail slider structure in the prior art for slide guiding. The inner door 2 and the outer door 3 can also adopt door structures such as a vertical hinged door, a lifting door and the like in other prior art to realize opening and closing.

The pressing plate driving part comprises a pressing plate driving motor, a lead screw 23 connected to the output end of the pressing plate driving motor and a lead screw nut 24 matched on the lead screw 23, the lead screw nut 24 is fixedly connected with the pressing plate 20, and the pressing plate driving motor is fixed on the sliding plate 19. The pressure plate driving motor drives the screw 23 to rotate, so as to drive the screw nut 24 and the pressure plate 20 to move telescopically relative to the sliding plate 19. The platen driver may also employ other prior art linear drive elements such as pneumatic cylinders and the like.

The outer door driving mechanism comprises an outer door body driving motor, a gear 25 connected to the output end of the outer door body driving motor, and a rack 26 meshed with the gear 25, wherein the rack 26 is fixedly connected with the sliding plate 19. Other prior art arrangements such as motor-screw drive arrangements, motor and sprocket-chain drive arrangements, etc. may also be used.

The present invention is not limited to the above-mentioned optional embodiments, and any other products in various forms can be obtained by anyone under the teaching of the present invention, and any changes in the shape or structure thereof, all the technical solutions falling within the scope of the present invention, are within the protection scope of the present invention.

Claims

1. A sample precooling library plate structure for a biological sample library cantilever tube area is characterized by comprising a library plate, an inner door and an outer door; the inner surface of the library plate facing to the biological sample library selecting pipe area and the outer surface of the library plate deviating from the biological sample library selecting pipe area are provided, the library plate is provided with a precooling cavity penetrating to the inner surface and the outer surface of the library plate, and a plurality of layers of sample box placing tables are arranged in the precooling cavity; the inner door and the outer door are respectively and correspondingly arranged at the positions of the precooling cavities on the inner surface and the outer surface of the storehouse plate so as to seal the precooling cavities.

2. The sample pre-cooling library plate structure in the biological sample library cantilever tube area according to claim 1, wherein the sample box placing table comprises a placing plate fixed on the inner wall of the pre-cooling cavity and limiting strips fixed on two sides of the placing plate, and a sample box placing area is arranged between the two limiting strips.

3. The sample pre-cooling reservoir plate structure for the biological sample reservoir cantilever area according to claim 2, wherein two ends of the opposite surfaces of the two limiting strips are provided with guiding inclined surfaces.

4. The sample pre-cooling storage plate structure in the biological sample storage cantilever area according to claim 1, wherein the inner door comprises an inner door body for closing the pre-cooling cavity, two connecting rods respectively fixed at two ends of the inner door body, and two door opening devices respectively connected to the two connecting rods; the door opening devices comprise swing rods, inner door driving mechanisms for driving the swing rods to rotate, fixed guide rails parallel to the swing rods, and sliding blocks in sliding fit with the fixed guide rails, wherein one ends of connecting rods are hinged with the swing rods, and the other ends of the connecting rods are hinged with the sliding blocks; the inner door driving mechanism and the fixed guide rail are fixed on the inner surface of the warehouse board.

5. The sample pre-cooling storage plate structure in the biological sample storage cantilever tube area according to claim 4, wherein the inner door body comprises an inner door plate, an inner door heat-insulation and heat-preservation plate and an inner door sealing strip, the inner door heat-insulation and heat-preservation plate is fixed on the surface of the inner door plate facing the pre-cooling cavity, and the inner door sealing strip is arranged around the inner door heat-insulation and heat-preservation plate.

6. The sample pre-cooling storage plate structure in the biological sample storage cantilever area according to claim 1 or 4, wherein the outer door comprises an outer door body and an outer door driving mechanism for driving the outer door body to slide on the outer surface of the storage plate; the outer door body includes slide plate, clamp plate and the clamp plate driving piece that the drive clamp plate removed to the precooling chamber, and the clamp plate driving piece is fixed in the slide plate.

7. The sample pre-cooling storage plate structure in the biological sample storage cantilever area according to claim 6, wherein an outer door heat insulation plate is fixed on the surface of the pressing plate facing the pre-cooling cavity, and an outer door sealing strip located around the outer door heat insulation plate is arranged on the pressing plate.

8. The structure of the pre-cooled sample storage plate in the cantilever tube area of the biological sample storage as claimed in claim 6, wherein the pressing plate driving member comprises a pressing plate driving motor, a lead screw connected to the output end of the pressing plate driving motor, and a lead screw nut fitted on the lead screw, the lead screw nut is fixedly connected with the pressing plate, and the pressing plate driving motor is fixed on the sliding plate.