CN210953503U - Micropore even pressure prevents capillary fast sampling fluid detection device - Google Patents

Micropore even pressure prevents capillary fast sampling fluid detection device Download PDF

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Publication number
CN210953503U
CN210953503U CN201921479221.6U CN201921479221U CN210953503U CN 210953503 U CN210953503 U CN 210953503U CN 201921479221 U CN201921479221 U CN 201921479221U CN 210953503 U CN210953503 U CN 210953503U
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CN
China
Prior art keywords
test paper
paper placing
placing groove
sampling fluid
fast sampling
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Active
Application number
CN201921479221.6U
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Chinese (zh)
Inventor
高飞
王海剑
陆维克
张晨
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Hangzhou Alltest Biotech Co ltd
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Hangzhou Alltest Biotech Co ltd
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Application filed by Hangzhou Alltest Biotech Co ltd filed Critical Hangzhou Alltest Biotech Co ltd
Priority to CN201921479221.6U priority Critical patent/CN210953503U/en
Priority to PCT/CN2019/110908 priority patent/WO2021042447A1/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14Suction devices, e.g. pumps; Ejector devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Abstract

The utility model discloses a micropore even pressure prevents capillary fast sampling fluid detection device. The liquid end of the bottom of the installation groove of the traditional fluid detection insert is easy to generate air bubbles, so that the detection speed is greatly reduced. The utility model comprises a bearing sheet. The working side surface of the bearing sheet is provided with a test paper placing groove. Reagent strips are arranged in the test paper placing grooves. The bottom of the test paper placing groove is provided with an exhaust pressure equalizing hole. The bottom of the test paper placing groove is provided with a transverse capillary-proof groove. The utility model discloses a set up the mode in exhaust pressure-equalizing hole at the test paper settling tank bottom, improved greatly the utility model discloses a sampling speed has improved inspection efficiency to fog into the problem that the interpretation of water droplet influences the result in the cavity has been solved. The utility model discloses an it has 3 horizontal capillary groove's of preventing mode to add at the test paper arrangement tank bottom, has solved the problem that NC membrane reaction zone was infiltrated before the release district, has avoided unusual chromatography result.

Description

Micropore even pressure prevents capillary fast sampling fluid detection device
Technical Field
The utility model belongs to the technical field of the fluid detects, concretely relates to capillary fluid detection inserted sheet is prevented to micropore even pressure.
Background
Although the traditional fluid detection insert can accurately detect the result, the sampling speed is low, the chromatography is uneven, air bubbles are easily generated at the liquid collection end at the bottom of the placement groove, the reagent sampling speed is influenced due to overhigh air pressure in the cavity of the placement groove, and the subsequent interpretation is influenced due to the fact that the temperature of the reaction liquid is higher than the external temperature and the water vapor is easily formed on the inner wall of the cavity. In addition, the liquid is often faster than the absorption speed of the front sample pad by utilizing the capillary action at the back of the reagent, so that the NC membrane reaction area is earlier wet than the gold mark release area, the normal bottom-up chromatography reaction of the reagent is influenced, and the chromatography of a fluid sample cannot be smoothly carried out in use.
Disclosure of Invention
An object of the utility model is to provide a capillary sampling fluid detection device is prevented to micropore even pressure.
The utility model comprises a bearing sheet. And a test paper placing groove is arranged on the working side surface of the bearing sheet. Reagent strips are arranged in the test paper placing grooves. The bottom of the test paper placing groove is provided with an exhaust pressure equalizing hole. The bottom of the test paper placing groove is provided with a transverse capillary-proof groove.
Preferably, a mushroom cavity is formed in the top end of the test paper accommodating groove, and the width of the mushroom cavity is gradually increased along the direction from the bottom end to the top end of the test paper accommodating groove. The top end surface of the mushroom cavity is a plane.
Preferably, the bottom ends of the test paper placing grooves are provided with cornice openings, and the top ends of the test paper placing grooves are in an oblique wedge shape.
Preferably, the top end and the bottom end of the side wall of the test paper placing groove are respectively provided with an upper clamp and a lower clamp.
Preferably, the test paper placing grooves are n in total, and n is less than or equal to 20; the n test paper placing grooves are communicated with the bottom edge of the bearing sheet. The bottom end of the reagent strip extends out of the corresponding test paper placing groove.
Preferably, the longitudinal direction of the lateral capillary-proof groove is parallel to the width direction of the test paper-placing groove.
Preferably, the exhaust pressure equalizing holes are positioned on the symmetrical surfaces of the two side surfaces of the corresponding test paper placing groove.
Preferably, the utility model also comprises a cover plate; the cover plate covers the working side surface of the bearing plate; the top edge of the cover sheet is aligned with the top edge of the carrier sheet; the distance from the bottom edge to the top edge of the cover sheet is greater than the distance from the bottom edge to the top edge of the carrier sheet.
Preferably, the cover plate is made of transparent materials.
Preferably, the cover plate is provided with an observation window corresponding to the test paper accommodating groove.
The utility model has the advantages that:
1. the utility model discloses a set up the mode in exhaust pressure-equalizing hole at the test paper settling tank bottom, improved greatly the utility model discloses a sampling speed has improved inspection efficiency to fog into the problem that the interpretation of water droplet influences the result in the cavity has been solved.
2. The utility model discloses an it has 3 horizontal capillary groove's of preventing mode to add at the test paper arrangement tank bottom, has solved the problem that NC membrane reaction zone was infiltrated before the release district, has avoided unusual chromatography result.
3. The utility model discloses an add the mode that cornice, top expand into "mushroom head" outward in test paper arrangement groove bottom, make the utility model discloses the equipment of reagent is more convenient, stable, high-efficient.
4. The utility model discloses can accomplish the sampling of many reagent strips simultaneously, and then realize the multinomial index synchronous detection of same sample.
Drawings
Fig. 1 is a schematic view of the overall structure of embodiment 1 of the present invention;
fig. 2 is a schematic side view of the overall structure in embodiment 1 of the present invention;
fig. 3 is a schematic front view of a test paper accommodating slot in embodiment 1 of the present invention.
Fig. 4 is a schematic side view of a test paper accommodating slot in embodiment 1 of the present invention.
Fig. 5 is a schematic side view of a test paper accommodating slot in embodiment 3 of the present invention.
Detailed Description
The present invention will be further explained with reference to the accompanying drawings.
Example 1
As shown in figures 1 and 2, the microporous pressure-equalizing anti-capillary fast sampling fluid detection device comprises a cover sheet 1 and a carrier sheet 4. The bearing sheet 4 is in a fan-shaped ring shape. N test paper placing grooves 2 are arranged on the working side surface of the bearing sheet 4 in sequence, wherein n is 14. The n test paper placing grooves 2 are all communicated with the bottom edge of the bearing sheet 4. The n test paper placing grooves 2 are all arranged along the radial direction of the bottom edge of the bearing sheet 4. Reagent strips are arranged in the n test paper placing grooves 2. The reagent strip adopts a colloidal gold reagent strip. The bottom end of the reagent strip extends out of the corresponding test paper placing groove 2. An upper staple bolt 2-1 and a lower staple bolt 2-2 are arranged at the upper end and the lower end of the side wall of the test paper placing groove 2, and the upper staple bolt 2-1 and the lower staple bolt 2-2 can clamp the reagent strip, so that the reagent strip is prevented from sliding along the length direction of the test paper placing groove 2.
As shown in fig. 1, 3 and 4, a mushroom cavity 5 is formed at the top end of the test paper seating groove 2, and the width of the mushroom cavity 5 is gradually increased along the direction from the bottom end to the top end of the test paper seating groove 2. The top end surface of the mushroom cavity 5 is a plane. Because the top end space of the test paper placing groove 2 is enlarged, compared with a test paper groove with a chamfer angle at the top end in the prior art, the test paper placing groove 2 can ensure that all reagent strips are better installed on the same horizontal line, so that the detection precision is improved, and the detection result is better observed. The bottom end of each test paper placing groove 2 is provided with an opening of an eave. The sectional area of the opening of the cornice is sequentially increased from inside to outside, which is beneficial to the entering of the sample liquid to be measured. The bottom of each test paper placing groove 2 is provided with an exhaust pressure equalizing hole 7. The exhaust pressure equalizing hole 7 is a through hole. The exhaust pressure equalizing hole 7 is positioned on the symmetrical surface corresponding to the two side surfaces of the test paper placing groove 2.
When bubbles are generated at the bottom end cornice opening of the test paper placing groove 2, the exhaust pressure equalizing hole 7 is communicated with the tested sample liquid outside the test paper placing groove 2, so that the exhaust pressure equalizing hole 7 can guide the bubbles at the cornice opening into the tested sample liquid, and the situation that sampling is stopped or the sampling speed is too slow is avoided. Meanwhile, the air bubbles led out by the exhaust pressure equalizing holes 7 can also reduce the condition that the cavity is fogged to form wall-sticking water drops.
The bottom of the test paper placing groove 2 is provided with three transverse capillary-proof grooves which are sequentially arranged at intervals along the length direction of the test paper placing groove 2. The longitudinal direction of the transverse capillary-proof groove is parallel to the width direction of the corresponding test paper placing groove 2. When the sample liquid to be detected rises along the gap between the bottom surface of the test paper placing groove 2 and the reagent strip, the three horizontal capillary-preventing grooves can store part of the sample liquid to be detected, so that the sample liquid to be detected is prevented from rising too fast, and the NC membrane reaction area of the reagent strip is soaked by the sample liquid to be detected before the release area is wetted, so that the abnormal chromatography result is caused.
The cover plate 1 is in a fan-shaped ring shape. The cover sheet 1 is made of transparent polyethylene. The cover sheet 1 covers the working side of the carrier sheet 4. The top edge of the cover sheet 1 is aligned with the top edge of the carrier sheet 4. The outer diameter of the cover plate 1 is equal to the outer diameter of the carrier plate 4. The inner diameter of the cover plate 1 is smaller than that of the bearing plate 4, so that the bottom edge of the cover plate 1 exceeds the bottom edge of the bearing plate 4, and the reagent strip extending out of the test paper accommodating groove 2 can be protected.
As a preferred technical solution, the carrier sheet 4 is a molded plastic product.
The working principle of the utility model is as follows:
the user takes out the cover plate 1 and the bearing plate 4 after immersing the bottoms of the cover plate and the bearing plate into the sample liquid to be measured; in the immersion process, the sample solution to be measured rises along the gap in the test paper accommodating groove 2 and is absorbed by the reagent strip. The test strip reacts under the action of the test sample liquid. When the bottom cornice opening of test paper resettlement groove 2 goes out and produces the bubble, the bubble is discharged from the exhaust pressure-equalizing hole for the reagent strip is more quick and even to the absorption of being surveyed sample liquid. When the size of the container for containing the measured sample liquid is small, the bearing sheet 4 is flexible sheet plastic and is in a fan-shaped ring shape, so that the bearing sheet can be rolled into a funnel shape, and the bottom of the bearing sheet extends into the container for containing the measured sample liquid, so that sampling is realized.
In addition, 3 horizontal anti-capillary grooves on the test paper placing groove 2 can prevent the back of the reagent strip from generating capillary phenomenon, thereby ensuring that the tested sample liquid firstly infiltrates the release area and then infiltrates the NC membrane reaction area.
Example 2
This example differs from example 1 in that: the cover plate 1 is made of non-transparent material. The cover plate 1 is provided with n observation windows respectively corresponding to the n test paper placing grooves 2.
Example 3
As shown in fig. 5, the present embodiment is different from embodiment 1 in that: the top of the test paper accommodating groove 2 is in an oblique wedge shape 8, namely the depth gradually decreases along the direction from the bottom end to the top end of the test paper accommodating groove 2. The top of the angled wedge 8 can facilitate the insertion and securing of the reagent strip.

Claims (10)

1. A micropore uniform pressure anti-capillary fast sampling fluid detection device comprises a bearing sheet; the method is characterized in that: a test paper placing groove is formed in the working side surface of the bearing sheet; reagent strips are arranged in the test paper accommodating grooves; the bottom end of the test paper placing groove is provided with an exhaust pressure equalizing hole; the bottom of the test paper placing groove is provided with a transverse capillary-proof groove.
2. The microporous, uniform pressure, anti-wicking, fast sampling fluid testing device of claim 1, wherein: the top end of the test paper placing groove is provided with a mushroom cavity, and the width of the mushroom cavity is gradually enlarged along the direction from the bottom end to the top end of the test paper placing groove; the top end surface of the mushroom cavity is a plane.
3. The microporous, uniform pressure, anti-wicking, fast sampling fluid testing device of claim 1, wherein: the bottom of the test paper placing groove is provided with an eave opening, and the top of the test paper placing groove is in an oblique wedge shape.
4. The microporous, uniform pressure, anti-wicking, fast sampling fluid testing device of claim 1, wherein: the top end and the bottom end of the side wall of the test paper placing groove are respectively provided with an upper staple bolt and a lower staple bolt.
5. The microporous, uniform pressure, anti-wicking, fast sampling fluid testing device of claim 1, wherein: the test paper placing grooves are n in total, and n is less than or equal to 20; the n test paper placing grooves are communicated with the bottom edge of the bearing sheet; the bottom end of the reagent strip extends out of the corresponding test paper placing groove.
6. The microporous, uniform pressure, anti-wicking, fast sampling fluid testing device of claim 1, wherein: the length direction of the transverse capillary-proof groove is parallel to the width direction of the test paper placing groove.
7. The microporous, uniform pressure, anti-wicking, fast sampling fluid testing device of claim 1, wherein: the exhaust pressure equalizing holes are positioned on the symmetrical surfaces of the two side surfaces of the corresponding test paper placing groove.
8. The microporous, uniform pressure, anti-wicking, fast sampling fluid testing device of claim 1, wherein: also comprises a cover plate; the cover plate covers the working side surface of the bearing plate; the top edge of the cover sheet is aligned with the top edge of the carrier sheet; the distance from the bottom edge to the top edge of the cover sheet is greater than the distance from the bottom edge to the top edge of the carrier sheet.
9. The microporous, uniform pressure, anti-wicking, fast sampling fluid testing device of claim 8, wherein: the cover plate is made of transparent material.
10. The microporous, uniform pressure, anti-wicking, fast sampling fluid testing device of claim 8, wherein: the cover plate is provided with an observation window corresponding to the test paper placing groove.
CN201921479221.6U 2019-09-06 2019-09-06 Micropore even pressure prevents capillary fast sampling fluid detection device Active CN210953503U (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201921479221.6U CN210953503U (en) 2019-09-06 2019-09-06 Micropore even pressure prevents capillary fast sampling fluid detection device
PCT/CN2019/110908 WO2021042447A1 (en) 2019-09-06 2019-10-13 Micropore pressure-equalizing anti-capillary fast-sampling fluid test device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201921479221.6U CN210953503U (en) 2019-09-06 2019-09-06 Micropore even pressure prevents capillary fast sampling fluid detection device

Publications (1)

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CN210953503U true CN210953503U (en) 2020-07-07

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WO (1) WO2021042447A1 (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8470609B2 (en) * 2007-09-11 2013-06-25 Jian Feng Chen Versatile drug testing device
CN201421446Y (en) * 2008-09-18 2010-03-10 艾博生物医药(杭州)有限公司 Carrier for supporting test reagent strip
US8844725B2 (en) * 2010-01-20 2014-09-30 Roche Diagnostics Operations, Inc. Test strip container with strip retainer and methods of manufacturing and utilization thereof
CN202159057U (en) * 2011-06-01 2012-03-07 杭州安旭科技有限公司 Rapid detection device
CN103424547B (en) * 2013-08-15 2015-02-25 广州万孚生物技术股份有限公司 Liquid detection cup and method for manufacturing same
CN105044102B (en) * 2015-08-10 2019-02-01 杭州康永生物技术有限公司 Test strips inserted sheet, manufacturing method and detection device for detection cup
CN207198160U (en) * 2016-07-27 2018-04-06 杭州博拓生物科技股份有限公司 A kind of carrier for preventing detection reagent bar mighty torrent
CN108387718A (en) * 2017-12-22 2018-08-10 杭州博拓生物科技股份有限公司 The detection device of analyte in a kind of detection fluid sample

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