CN210923718U - Kit for extracting free nucleic acid - Google Patents
Kit for extracting free nucleic acid Download PDFInfo
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- CN210923718U CN210923718U CN201921397294.0U CN201921397294U CN210923718U CN 210923718 U CN210923718 U CN 210923718U CN 201921397294 U CN201921397294 U CN 201921397294U CN 210923718 U CN210923718 U CN 210923718U
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Abstract
The utility model relates to a kit technical field, and disclose free nucleic acid and draw kit, including casing and cap, it is articulated with the lateral wall of cap that the connecting block is passed through on the top of casing, the outer wall fixedly connected with fixed establishment of casing, the rubber ring of two symmetric distributions of the inner wall fixedly connected with of cap, the common swing joint of inner wall of two rubber rings has the collection cleaning mechanism, the inner wall swing joint of casing has the baffle, the last sliding surface of baffle is connected with stop gear, the recess with stop gear matched with has been seted up to the inner wall of casing, the inner wall swing joint of casing has the rack, the lower fixed surface of rack is connected with ejection mechanism. The utility model discloses can effectively improve the fastness of kit, avoid the interior component of kit to lose, and then ensure that the kit can normally draw nucleic acid, also can effectively improve the abluent convenience of magnetic bead, labour saving and time saving has reduced staff's intensity of labour, has improved the efficiency that nucleic acid drawed simultaneously.
Description
Technical Field
The utility model relates to a kit technical field especially relates to free nucleic acid draws kit.
Background
Nucleic acids are composed of nucleotides, while nucleotide monomers are composed of a 5-carbon sugar, a phosphate group and a nitrogenous base, if the 5-carbon sugar is ribose, the polymer formed is RNA; if the 5-carbon sugar is deoxyribose, the formed polymer is DNA, magnetic beads in magnetic bead method nucleic acid extraction can be specifically identified and efficiently combined with nucleic acid molecules on a microscopic interface, DNA and RNA can be separated from samples such as blood, animal tissues, food, pathogenic microorganisms and the like under the action of guanidine hydrochloride and an external magnetic field by utilizing the superparamagnetism of silicon oxide nano microspheres, the kit can be applied to clinical disease diagnosis, the nucleic acid extraction kit is a high and new technology product integrating bioscience and nano material science, and the magnetic bead method nucleic acid is based on the same principle as a silica gel membrane centrifugal column.
The existing free nucleic acid extraction kit is packaged by a paper box, the firmness of the paper box is poor, the kit is easy to damage, internal elements of the kit are easily lost, the normal extraction of nucleic acid is influenced, in addition, the cleaning of magnetic beads after the extraction of nucleic acid is inconvenient, time and labor are wasted, the labor intensity of workers is increased, and the efficiency of the extraction of nucleic acid is influenced.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving among the prior art free nucleic acid and drawing kit and adopt the carton packing, because of the carton fastness is relatively poor, damage easily, and then lead to the kit internal member to lose easily, influence nucleic acid and normally draw, in addition, the magnetic bead washs comparatively inconveniently after the present nucleic acid draws, and is consuming time hard, has increased staff's intensity of labour, and then influences the problem of nucleic acid extraction efficiency, and the free nucleic acid who proposes draws the kit.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
free nucleic acid draws kit, including casing and cap, the top of casing is articulated through the lateral wall of connecting block and cap, the outer wall fixedly connected with fixed establishment of casing, the rubber ring of two symmetric distributions of inner wall fixedly connected with of cap, two the common swing joint of inner wall of rubber ring has the collection cleaning mechanism, the inner wall swing joint of casing has the baffle, the last sliding surface of baffle is connected with stop gear, the recess with stop gear matched with is seted up to the inner wall of casing, the inner wall swing joint of casing has the rack, the lower fixed surface of rack is connected with ejection mechanism.
Preferably, the fixing mechanism comprises a first sliding block slidably connected with the outer wall of the casing, a first sliding chute matched with the first sliding block is formed in the outer wall of the casing, a supporting block is fixedly connected to the outer wall of the first sliding block, two fixing rods symmetrically distributed are fixedly connected to the upper surface of the supporting block, a fixing blind hole matched with the fixing rods is formed in the lower surface of the casing cover, a connecting rod is fixedly connected to the lower surface of the supporting block, a fixing ring is movably sleeved on the rod wall of the connecting rod, the outer wall of the fixing ring is fixedly connected with the outer wall of the casing, a reset spring is movably sleeved on the rod wall of the connecting rod, and two ends of the reset spring are fixedly connected with the lower surface of the supporting block and.
Preferably, collect wiper mechanism include with rubber ring inner wall swing joint's pipe, the inner wall fixedly connected with pipe of pipe, the one end fixedly connected with collar that the pipe was kept away from to the pipe, a plurality of elasticity ropes of inner wall fixedly connected with of collar, the one end outer wall threaded connection that the pipe was kept away from to the pipe has the tube cap, the outer wall threaded connection that the pipe was kept away from to the pipe has sealed lid, the inner wall fixedly connected with of pipe washs the brush.
Preferably, stop gear includes two second sliders with baffle lower surface sliding connection, two the equal fixedly connected with gag lever post of the one end that the second slider carried on the back mutually, two the equal fixedly connected with gag lever post of the one end that the gag lever post carried on the back mutually has all fixedly cup jointed the rubber sleeve, the inner wall swing joint of recess in the outer wall of rubber sleeve and the casing, the second spout with second slider matched with is seted up to the upper surface of baffle.
Preferably, the ejection mechanism comprises a U-shaped plate fixedly connected with the lower surface of the placing frame, the upper surface of the U-shaped plate is provided with a plurality of rectangular through holes, the hole walls of the rectangular through holes are movably connected with T-shaped square rods, and the bottom ends of the T-shaped square rods are fixedly connected with push blocks.
Preferably, the shell cover, the partition plate and the placing frame are all made of plastics.
Preferably, the outer walls of the fixed rod and the shell cover are fixedly connected with rubber pads.
Preferably, the upper surface of the placing rack is fixedly connected with two symmetrically distributed connecting ropes, and the top ends of the connecting ropes are fixedly connected with pull rings.
Preferably, the rack is including placing dish and supporting leg, place the upper surface of dish and seted up a plurality of holes of placing.
Compared with the prior art, the utility model provides a free nucleic acid draws kit possesses following beneficial effect:
1. the free nucleic acid extraction kit is provided with a height rod, a reset spring, a first slider and a partition plate, when the kit is required to be used for extracting nucleic acid, a shell cover is opened, a supporting block is firstly pulled and downwards moves in a first sliding groove through the first slider, then the supporting block extrudes the reset spring, a fixed rod is further separated from a fixed blind hole, then the shell cover is opened, an instrument is taken out, a limiting rod and a rubber sleeve are separated from a groove in the shell through a second slider, finally the partition plate is opened, a placing frame is taken out, the nucleic acid extraction operation is finally carried out, a worker can conveniently take out a cryopreserved tube on the placing frame through the upward top end of a T-shaped square rod, the convenience of the kit for extracting nucleic acid is improved, the kit can be prevented from being damaged through a plastic kit, the mechanism can effectively improve the firmness of the kit, and, thereby ensuring that the kit can normally extract nucleic acid.
2. This free nucleic acid draws kit, through being provided with the elastic cord, pipe and clearance brush, finish when nucleic acid extraction and need wash the magnetic bead so that when using next time, at first open the tube cap, make the elastic cord and the magnetic bead contact of pipe bottom simultaneously, make the magnetic bead squeeze into the pipe from the gap between the elastic cord, add the washing liquid and close the tube cap after that, then rock the pipe, make the magnetic bead in the pipe fully contact with the washing brush and wash, the guarantee can the sanitization, open sealed lid at last, make magnetic bead and washing liquid pour out, this process makes the magnetic bead wash convenient laborsaving, this mechanism can effectively improve the abluent convenience of magnetic bead, time saving and labor saving, staff's intensity of labour has been reduced, the efficiency of nucleic acid extraction has been improved simultaneously.
The part that does not relate to in the device all is the same with prior art or can adopt prior art to realize, the utility model discloses can effectively improve the fastness of kit, avoid the interior component of kit to lose, and then ensure that the kit can normally draw nucleic acid, also can effectively improve the abluent convenience of magnetic bead, labour saving and time saving has reduced staff's intensity of labour, has improved the efficiency that nucleic acid drawed simultaneously.
Drawings
FIG. 1 is a schematic structural diagram of a free nucleic acid extraction kit according to the present invention;
FIG. 2 is a schematic view of a local structure of the free nucleic acid extraction kit according to the present invention;
FIG. 3 is a schematic structural diagram of a portion A of the free nucleic acid extraction kit of the present invention;
FIG. 4 is a schematic structural diagram of the free nucleic acid extraction kit B of the present invention.
In the figure: the device comprises a shell body 1, a shell cover 2, a fixing mechanism 3, a first sliding block 31, a first sliding groove 32, a supporting block 33, a fixing rod 34, a fixing blind hole 35, a connecting rod 36, a fixing ring 37, a return spring 38, a rubber ring 4, a collecting and cleaning mechanism 5, a circular tube 51, a guide tube 52, a mounting ring 53, an elastic rope 54, a tube cover 55, a sealing cover 56, a cleaning brush 57, a partition plate 6, a limiting mechanism 7, a second sliding block 71, a limiting rod 72, a rubber sleeve 73, a second sliding groove 74, a placing frame 8, a push-out mechanism 9, a U-shaped plate 91, a square rod 92T-shaped, a push block 93 and a pull.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
Referring to fig. 1-4, free nucleic acid draws kit, including casing 1 and cap 2, the top of casing 1 is articulated through the lateral wall of connecting block and cap 2, the outer wall fixedly connected with fixed establishment 3 of casing 1, the rubber ring 4 of two symmetric distributions of the inner wall fixedly connected with of cap 2, the common swing joint of the inner wall of two rubber ring 4 has collection cleaning mechanism 5, the inner wall swing joint of casing 1 has baffle 6, the last sliding surface of baffle 6 has stop gear 7, the recess with stop gear 7 matched with is seted up to the inner wall of casing 1, the inner wall swing joint of casing 1 has rack 8, the lower fixed surface of rack 8 is connected with ejection mechanism 9.
The fixing mechanism 3 comprises a first sliding block 31 connected with the outer wall of the shell 1 in a sliding manner, the outer wall of the shell 1 is provided with a first sliding chute 32 matched with the first sliding block 31, the outer wall of the first sliding block 31 is fixedly connected with a supporting block 33, the upper surface of the supporting block 33 is fixedly connected with two fixing rods 34 which are symmetrically distributed, the lower surface of the shell cover 2 is provided with a fixing blind hole 35 matched with the fixing rod 34, the lower surface of the supporting block 33 is fixedly connected with a connecting rod 36, the rod wall of the connecting rod 36 is movably sleeved with a fixing ring 37, the outer wall of the fixing ring 37 is fixedly connected with the outer wall of the shell 1, the rod wall of the connecting rod 36 is movably sleeved with a return spring 38, two ends of the return spring, the mechanism can effectively improve the firmness of the kit, avoid the loss of elements in the kit, and further ensure that the kit can normally extract nucleic acid.
The collecting and cleaning mechanism 5 comprises a circular tube 51 movably connected with the inner wall of the rubber ring 4, a conduit 52 is fixedly connected with the inner wall of the circular tube 51, a mounting ring 53 is fixedly connected with one end of the conduit 52 far away from the circular tube 51, a plurality of elastic ropes 54 are fixedly connected with the inner wall of the mounting ring 53, a tube cover 55 is connected with the outer wall of one end of the conduit 52 far away from the circular tube 51 in a threaded manner, a sealing cover 56 is connected with the outer wall of the circular tube 51 far away from the conduit 52 in a threaded manner, a cleaning brush 57 is fixedly connected with the inner wall of the circular tube 51, when the nucleic acid extraction is finished and the magnetic beads need to be cleaned for next use, firstly, a tube cover 55 is opened, meanwhile, the elastic ropes 54 at the bottom end of the conduit 52 are contacted with the magnetic beads, the magnetic beads are squeezed into the conduit 52 from gaps among the, the guarantee can the sanitization, opens sealed lid 56 at last, makes magnetic bead and washing liquid pour out, and this process makes the magnetic bead wash convenient laborsaving, and this mechanism can effectively improve the abluent convenience of magnetic bead, and labour saving and time saving has reduced staff's intensity of labour, has improved the efficiency of nucleic acid extraction simultaneously.
The materials of the shell 1, the shell cover 2, the partition plate 6 and the placing rack 8 are plastics, so that the firmness of the kit can be effectively improved, the loss of elements in the kit is avoided, and the kit can be further ensured to normally extract nucleic acid.
The equal fixedly connected with rubber pad of outer wall of dead lever 34 and cap 2, the rubber pad can increase the stability that dead lever 34 and cap 2 are connected, can improve the stability that cap 2 and casing 1 are connected simultaneously, avoids the inside component of kit to lose, and guarantee nucleic acid draws and can normally go on.
The last fixed surface of rack 8 is connected with the connection rope of two symmetric distributions, connects the top fixedly connected with pull ring 10 of rope, and pull ring 10 and connection rope can be convenient for take out rack 8.
The rack 8 is including placing dish and supporting leg, and the upper surface of placing the dish has been seted up a plurality of holes of placing, places the hole and is convenient for place and freeze the pipe, can improve and freeze the stability of depositing the pipe and placing.
In the utility model, when the kit is required to be used for extracting nucleic acid, the shell cover 2 is opened, the supporting block 33 is firstly pulled, the supporting block 33 moves downwards in the first sliding groove 32 through the first slider 31, then the supporting block 33 extrudes the reset spring 38, further the fixing rod 37 is separated from the fixing blind hole 35, then the shell cover 2 is opened, then the instrument is taken out, meanwhile, the limiting rod 72 and the rubber sleeve 73 are separated from the inner groove of the shell body 1 through the second slider 71, finally, the clapboard 6 is opened, the placing frame 8 is taken out, finally, the nucleic acid extraction operation is carried out, and the freezing tube on the placing frame 8 can be conveniently taken out by a worker through the upward top end of the T-shaped square rod 92, the convenience of the kit for extracting nucleic acid is improved, the kit can be prevented from being damaged by the plastic kit, the mechanism can effectively improve the firmness of the kit, when nucleic acid extraction finishes and need wash the magnetic bead so that when using next time, at first open tube cap 55, make the elastic rope 54 and the magnetic bead contact of pipe 52 bottom simultaneously, make the magnetic bead squeeze into pipe 52 from the gap between elastic rope 54, add the washing liquid and close tube cap 55 after that, then rock pipe 51, make the magnetic bead in the pipe 51 fully contact with washing brush 57 and wash, the guarantee can the sanitization, open sealed lid 56 at last, make magnetic bead and washing liquid pour out, this process makes the magnetic bead wash convenient laborsaving, this mechanism can effectively improve the abluent convenience of magnetic bead, time saving and labor saving, staff's intensity of labour has been reduced, the efficiency of nucleic acid extraction has been improved simultaneously.
The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.
Claims (9)
1. The free nucleic acid extraction kit comprises a shell (1) and a shell cover (2), and is characterized in that, the top end of the shell (1) is hinged with the side wall of the shell cover (2) through a connecting block, the outer wall of the shell (1) is fixedly connected with a fixing mechanism (3), the inner wall of the shell cover (2) is fixedly connected with two symmetrically distributed rubber rings (4), the inner walls of the two rubber rings (4) are jointly and movably connected with a collecting and cleaning mechanism (5), the inner wall of the shell (1) is movably connected with a clapboard (6), the upper surface of the clapboard (6) is connected with a limiting mechanism (7) in a sliding way, the inner wall of the shell (1) is provided with a groove matched with the limiting mechanism (7), the inner wall swing joint of casing (1) has rack (8), the lower fixed surface of rack (8) is connected with ejection mechanism (9).
2. The free nucleic acid extraction kit according to claim 1, wherein the fixing mechanism (3) comprises a first slider (31) slidably connected to the outer wall of the housing (1), the outer wall of the housing (1) is provided with a first sliding slot (32) matched with the first slider (31), the outer wall of the first slider (31) is fixedly connected with a supporting block (33), the upper surface of the supporting block (33) is fixedly connected with two symmetrically distributed fixing rods (34), the lower surface of the housing cover (2) is provided with a fixing blind hole (35) matched with the fixing rods (34), the lower surface of the supporting block (33) is fixedly connected with a connecting rod (36), the rod wall of the connecting rod (36) is movably sleeved with a fixing ring (37), the outer wall of the fixing ring (37) is fixedly connected with the outer wall of the housing (1), the rod wall of the connecting rod (36) is movably sleeved with a return spring (38), and two ends of the return spring (38) are respectively fixedly connected with the lower surface of the supporting block (33) and the upper surface of the fixing ring (37).
3. The free nucleic acid extraction kit according to claim 1, wherein the collection and cleaning mechanism (5) comprises a circular tube (51) movably connected with the inner wall of the rubber ring (4), the inner wall of the circular tube (51) is fixedly connected with a guide tube (52), one end of the guide tube (52) far away from the circular tube (51) is fixedly connected with a mounting ring (53), the inner wall of the mounting ring (53) is fixedly connected with a plurality of elastic ropes (54), the outer wall of one end of the guide tube (52) far away from the circular tube (51) is in threaded connection with a tube cover (55), the outer wall of the circular tube (51) far away from the guide tube (52) is in threaded connection with a sealing cover (56), and the inner wall of the circular tube (51) is fixedly connected with a cleaning brush (.
4. The free nucleic acid extraction kit according to claim 1, wherein the limiting mechanism (7) comprises two second sliding blocks (71) slidably connected to the lower surface of the partition plate (6), limiting rods (72) are fixedly connected to opposite ends of the two second sliding blocks (71), rubber sleeves (73) are fixedly sleeved on opposite ends of the two limiting rods (72), the outer walls of the rubber sleeves (73) are movably connected with the inner walls of the grooves in the casing (1), and second sliding grooves (74) matched with the second sliding blocks (71) are formed in the upper surface of the partition plate (6).
5. The free nucleic acid extraction kit according to claim 1, wherein the ejection mechanism (9) comprises a U-shaped plate (91) fixedly connected with the lower surface of the placing rack (8), the upper surface of the U-shaped plate (91) is provided with a plurality of rectangular through holes, the wall of each rectangular through hole is movably connected with a T-shaped square rod (92), and the bottom end of each T-shaped square rod (92) is fixedly connected with a push block (93).
6. The free nucleic acid extraction kit according to claim 1, wherein the housing (1), the housing cover (2), the partition (6) and the rack (8) are all made of plastic.
7. The free nucleic acid extraction kit of claim 2, wherein the fixing rod (34) and the outer wall of the case cover (2) are fixedly connected with rubber pads.
8. The free nucleic acid extraction kit according to claim 5, wherein two symmetrically distributed connecting ropes are fixedly connected to the upper surface of the placing rack (8), and a pull ring (10) is fixedly connected to the top ends of the connecting ropes.
9. The free nucleic acid extraction kit according to claim 5, wherein the rack (8) comprises a placing tray and a supporting leg, and a plurality of placing holes are formed on the upper surface of the placing tray.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921397294.0U CN210923718U (en) | 2019-08-27 | 2019-08-27 | Kit for extracting free nucleic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921397294.0U CN210923718U (en) | 2019-08-27 | 2019-08-27 | Kit for extracting free nucleic acid |
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| Publication Number | Publication Date |
|---|---|
| CN210923718U true CN210923718U (en) | 2020-07-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921397294.0U Active CN210923718U (en) | 2019-08-27 | 2019-08-27 | Kit for extracting free nucleic acid |
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| CN (1) | CN210923718U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112226354A (en) * | 2020-09-10 | 2021-01-15 | 襄阳市远杰精密机械有限公司 | Multi-sample universal full-automatic nucleic acid extraction instrument |
-
2019
- 2019-08-27 CN CN201921397294.0U patent/CN210923718U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112226354A (en) * | 2020-09-10 | 2021-01-15 | 襄阳市远杰精密机械有限公司 | Multi-sample universal full-automatic nucleic acid extraction instrument |
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