CN210923234U - Sample blending system and sample analyzer - Google Patents

Sample blending system and sample analyzer Download PDF

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Publication number
CN210923234U
CN210923234U CN201920776719.2U CN201920776719U CN210923234U CN 210923234 U CN210923234 U CN 210923234U CN 201920776719 U CN201920776719 U CN 201920776719U CN 210923234 U CN210923234 U CN 210923234U
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sample
sample container
container
blending
support plate
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李学荣
胡力坚
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Abstract

The utility model provides a sample mixing system and sample analyzer. The sample blending system for blending a sample in a sample container and comprising: a kneading unit having a sample container accommodating unit for accommodating a sample container and a sample container supporting unit for supporting the bottom of the sample container; the driving part is used for driving the sample container supporting part to move so as to drive the bottom of the sample container to move, so that the sample in the sample container is uniformly mixed; and the anti-shifting mechanism is used for preventing the sample container from shifting in the vertical direction in the sample container accommodating part in the sample blending process. According to the utility model discloses a sample mixing system and sample analysis appearance have and prevent that the sample container from following the anti-channeling mechanism of vertical direction drunkenness at sample mixing in-process, not only can prevent that the sample from splashing and having played the liquid particle adhesion and cause the influence to measuring result on the container inner wall, can also prevent the bar code on the sample container outer wall of wearing and tearing.

Description

Sample blending system and sample analyzer
Technical Field
The utility model relates to a blood sample analysis field, more specifically relate to a sample mixing system and sample analysis appearance that is used for carrying out the mixing to the blood sample of extraction, especially trace blood sample.
Background
Blood sample testing requires the collection of a certain amount of sample from a patient. The blood collection method is generally divided into venous blood collection and peripheral blood collection. Peripheral blood is often collected for patients who are not suitable for venous blood collection, such as neonates, infants, intensive care patients and the like.
In blood collection, a blood collection tube containing an anticoagulant is generally used to prevent blood coagulation. The blood consists of blood cells and plasma, and because the specific gravities of the blood cells and the plasma are different, the anticoagulated blood can be layered after standing for a period of time, so the blood sample needs to be fully mixed before measurement, otherwise, the measurement result has larger deviation.
The peripheral blood sample has small collection amount and poor fluidity, and cannot be mixed uniformly by adopting a reciprocating inversion sample container mode of uniformly mixing the venous blood sample, and a vortex mixing mode is usually adopted. In an implementation scheme of automatic peripheral blood sample introduction, a sample mixing device is arranged in an analyzer. The analyzer transports the sample containers from the sample rack to the sample blending device through the clamping jaws, and transports the blended sample containers back to the sample rack. The sample mixing device of the analyzer realizes the mixing of peripheral blood by vibrating the bottom of the sample container.
However, the sample mixing device has the disadvantages that the sample container is easy to move up and down during mixing, so that the sample can splash and liquid particles can adhere to the inner wall of the container, the proportion of cells in the sample is changed, and the measurement result is influenced. In addition, the up and down play of the sample container during blending may also wear the barcode on the outer wall of the sample container.
SUMMERY OF THE UTILITY MODEL
Based on the technical problem that the sample mixing technique among the prior art exists to and the urgent demand of market to tip blood full automatization measurement, the utility model discloses an aspect provides a sample mixing system, sample mixing system is arranged in the sample of mixing sample container and includes: a kneading unit having a sample container accommodating unit for accommodating a sample container and a sample container supporting unit for supporting the bottom of the sample container; the driving part is used for driving the sample container supporting part to move so as to drive the bottom of the sample container to move, so that the sample in the sample container is uniformly mixed; and the anti-shifting mechanism is used for preventing the sample container from shifting in the vertical direction in the sample container accommodating part in the sample blending process.
As one implementation, the anti-play mechanism may be configured as a pressing member that can press against the top of the sample container accommodated in the sample container accommodating portion to prevent the sample container from being played in the vertical direction.
As an implementation, the pressing element can be formed to be elastic.
As an implementation manner, the pressing component can move or not move relative to the blending part.
In one embodiment, the height of the pressing member is adjustable relative to the kneading section.
In one embodiment, the sample mixing system may further include a transport portion configured to transport a sample container into the sample container accommodating portion and to bring a bottom of the sample container into contact with the sample container supporting portion, and the pressing member may be provided on the transport portion.
As an implementation, the transport portion may include a jaw for gripping a sample container, and the pressing member may be configured as a platen disposed above the jaw.
As an implementation, the anti-play mechanism may be configured as a latch mechanism provided on the sample container support part for latching a bottom of a sample container supportable on the sample container support part to prevent the sample container from moving in a vertical direction.
As an implementation, the anti-play mechanism may be configured as a cylindrical groove formed on the sample container support portion, in which a bottom of the sample container is supported.
As an implementation manner, the driving portion may include a first driving unit and an eccentric block connected to each other, and the first driving unit drives the eccentric block to rotate, so as to drive the sample container support portion to swing together with the bottom of the sample container supported on the sample container support portion, so as to mix the sample in the sample container.
As an implementation manner, the blending part may include a first support plate, a flexible connecting member, and a second support plate, wherein the first support plate is provided with a sample container fixing hole as the sample container accommodating part, the second support plate is connected to the first support plate through the flexible connecting member, and the first driving unit and the sample container supporting part are fixed to the second support plate.
As one implementation, the flexible connecting member may include a flexible post or spring.
As an implementation, the first drive unit may be configured as a stepper motor, a dc motor or a servo motor.
As an implementation manner, the driving portion may further include a second driving unit and a slider, the first supporting plate is fixed on the slider, and the second driving unit is configured to drive the slider to drive the first supporting plate to move.
As an implementation manner, the driving portion may further include a third supporting plate, a sliding rail is disposed on the third supporting plate, and the slider is driven by the second driving unit to move along the sliding rail.
As an implementation manner, the sample mixing system may further include a sensor for detecting a movement state of the sample container support portion.
The utility model discloses an on the other hand provides a sample mixing system, sample mixing system is arranged in the sample of mixing sample container and includes: the blending part is provided with a sample container accommodating part for accommodating a sample container and a sample container supporting part for supporting the bottom of the sample container, wherein a cylindrical groove is formed in the sample container supporting part, and the bottom of the sample container is supported in the cylindrical groove; and the driving part is used for driving the sample container supporting part to move so as to drive the bottom of the sample container to move, so that the samples in the sample container are uniformly mixed.
A further aspect of the present invention provides a sample analyzer, the sample analyzer includes an analysis portion and any one of the above, the sample mixing system, the analysis portion is used for analyzing the sample of the mixing in the sample container.
As an implementation, the sample analyzer may further include a blending device for blending the venous blood sample, and the sample blending system is for blending the peripheral blood sample.
According to the utility model discloses a sample mixing system and sample analysis appearance have and prevent that the sample container from following the anti-channeling mechanism of vertical direction drunkenness at sample mixing in-process, not only can prevent that the sample from splashing and having played the liquid particle adhesion and cause the influence to measuring result on the container inner wall, can also prevent the bar code on the sample container outer wall of wearing and tearing.
Drawings
The above and other objects, features and advantages of the present invention will become more apparent by describing in more detail embodiments of the present invention with reference to the attached drawings. The accompanying drawings are included to provide a further understanding of the embodiments of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description, serve to explain the invention and not to limit the invention. In the drawings, like reference numbers generally represent like parts or steps.
FIG. 1 is a schematic structural diagram of a sample mixing apparatus;
FIG. 2 is a schematic diagram of the forces that cause the sample container to move up and down with the sample mixing apparatus of FIG. 1;
fig. 3 is a block diagram of a sample blending system according to an embodiment of the present invention;
fig. 4 is a perspective view of a sample blending system according to an embodiment of the present invention;
fig. 5 is a flowchart of a sample blending system according to an embodiment of the present invention;
fig. 6 to 10 are schematic diagrams of different states of a sample blending system according to an embodiment of the present invention;
fig. 11 is a perspective view of a sample analyzer according to an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, exemplary embodiments according to the present invention will be described in detail below with reference to the accompanying drawings.
Fig. 1 shows a schematic structural view of a sample mixing device 1 for mixing a peripheral blood sample. As shown in fig. 1, the sample-homogenizing device 1 may include a homogenizing part and a driving part, wherein the homogenizing part may include a sample-container-accommodating part 18 (here, a sample-container fixing hole) for accommodating the sample container 2 and a sample-container-supporting part 16 for supporting the bottom of the sample container 2. The drive part is used for driving the sample container carrier 16 to move, thereby driving the bottom of the sample container 2 to move, so as to mix the sample in the sample container 2. Further, the drive section also comprises a first drive unit 14 (here, for example, a motor) and an eccentric mass 15. The first drive unit 14 drives the eccentric mass 15 into a rotational movement, which brings the sample container holder 16 together with the bottom of the sample container 2 supported on the sample container holder 16 into a swinging movement in order to mix the sample in the sample container 2.
Specifically, as shown in fig. 1, the kneading part may include a first support plate 11, a flexible connecting member 13, and a second support plate 12. Wherein the sample vessel fixing hole 18 is provided on an upwardly extending portion 17 of the first support plate 11, the second support plate 12 is connected to the first support plate 11 by the flexible connecting member 13, the first driving unit 14 and the sample vessel supporting portion 16 are fixed to the second support plate 12, and the eccentric mass 15 is fixed to a rotation shaft of the first driving unit. When the first driving unit 14 drives the eccentric mass 15 to rotate, the eccentric mass 15 generates rotary vibration relative to the rotating shaft of the first driving unit 14, and since the second supporting plate 12 is supported by the flexible connecting component 13, the vibration generated by the eccentric mass 15 will drive the second supporting plate 12 to vibrate, thereby driving the sample container supporting part 16 to vibrate. The upwardly extending portion 17 of the first support plate 11 is provided with sample container fixing holes 18. When the sample container 2 is placed in the sample container fixing hole 18, the bottom of the sample container 2 abuts against the sample container support part 16, and the sample container support part 16 vibrates to drive the bottom of the sample container 2 to vibrate, so that the sample in the sample container 2 is uniformly mixed.
The sample mixing device shown in fig. 1 has the following problems: the sample container 2 is freely placed on the sample container support portion 16 by its own weight, and when the sample container support portion 16 brings the bottom of the sample container 2 to vibrate, the bottom of the sample container 2 is subjected to an acting force F of the sample container support portion 16, which causes the sample container 2 to move up and down, as shown in fig. 2. As shown in fig. 2, the direction of the force F is perpendicular to the tangent line of the contact point of the sample container support 16 and the bottom of the sample container 2, and the force F can be decomposed into a component F1 pointing to the axis of the sample container 2 and a component F2 pointing vertically upward, wherein the component F1 provides a centripetal force for the rotation of the bottom of the sample container 2, but the component F2 causes the sample container 2 to move upward, after the sample container 2 is strung upward, the bottom of the sample container is separated from the contact point with the sample container support 16, the force F of the sample container 2 applied to the bottom of the sample container 2 by the sample container holder 16 disappears, the sample container 2 slides downward under its own weight and contacts the sample container holder again, and the influence of the force F is restored again. And the sample container 2 moves up and down in a circulating manner. In this case, the up-and-down movement of the sample container 2 can drive the movement of the sample in the sample container 2, the sample can splash liquid particles to adhere to the inner wall of the container, and if the position of the liquid particles is sputtered is higher, the liquid particles can not flow back to the bottom of the sample container 2. Particularly, before the sample is mixed uniformly, blood cells and plasma in the sample (such as a blood sample) are obviously layered after the sample is stood for a long time, the blood cells are positioned below, and the plasma is positioned above. When the mixing is started, the sample container 2 moves up and down, and if plasma particles are sputtered onto the inner wall of the container at a higher position and cannot flow back, the proportion of cells in the sample is changed, and the measurement result is influenced.
In order to solve the problem, the utility model provides a sample mixing system. A sample blending system according to the present invention is described below with reference to the accompanying drawings.
Fig. 3 is a block diagram of a sample mixing system 100 according to an embodiment of the present invention. As shown in fig. 3, the sample tempering system 100 may include a tempering section 110, a drive section 120, and a tamper-proof mechanism 130. The kneading unit 110 includes a sample container accommodating unit for accommodating a sample container and a sample container support unit for supporting the bottom of the sample container. The driving part 120 is used for driving the sample container support part to move, so as to drive the bottom of the sample container to move, so as to mix the sample in the sample container. The anti-play mechanism 130 is used to prevent the sample container from moving vertically in the sample container receiving portion during the sample blending process.
As one implementation, the movement-preventing mechanism 130 may be configured as a pressing member that can press against the top of the sample container accommodated in the sample-container accommodating portion to prevent the sample container from moving in the vertical direction. Illustratively, the sample mixing system 100 further includes a transport portion (not shown in fig. 3) for transporting the sample container into the sample container accommodating portion and causing the bottom of the sample container to abut on the sample container support portion, and the abutting member may be provided on the transport portion. The sample blending system 100 of this implementation is described below with reference to fig. 4.
Fig. 4 shows a perspective view of a sample blending system 100 according to an embodiment of the present invention. As shown in fig. 4, the sample tempering system 100 may include a tempering section 110, a drive section 120, a tamper-proof mechanism 130, and a transport section. The kneading unit 110 includes a sample container accommodating unit 18 (here, a sample container fixing hole) for accommodating the sample container 2 and a sample container support unit 16 (also referred to as a sample container holder) for supporting the bottom of the sample container 2. The driving part may comprise a first driving unit 14 and an eccentric mass (not shown), the first driving unit 14 drives the eccentric mass to rotate, thereby driving the sample container support part 16 to swing together with the bottom of the sample container 2 supported on the sample container support part 16, so as to mix the sample in the sample container 2. The first drive unit 14 may be embodied, for example, as a stepping motor, a direct current motor or a servomotor. Further, the blending part may further include a first support plate 11, a flexible connection member 13 (e.g., a flexible column or a spring), and a second support plate 12. Wherein the sample vessel receiving portion 18 is provided as a sample vessel fixing hole on the upwardly extending portion 17 of the first support plate 11, the second support plate 12 is connected to the first support plate 11 by the flexible connecting member 13, and the first drive unit 14 and the sample vessel support portion 16 are fixed to the second support plate 12. When the first driving unit 14 drives the eccentric block to rotate, the eccentric block generates rotary vibration relative to the rotating shaft of the first driving unit 14, and the second supporting plate 12 is supported by the flexible connecting component 13, so that the vibration generated by the eccentric block drives the second supporting plate 12 to vibrate, and the sample container supporting part 16 is driven to vibrate. The upwardly extending portion 17 of the first support plate 11 is provided with sample container fixing holes as sample container receiving portions 18. When the sample container 2 is placed in the sample container fixing hole, the bottom of the sample container 2 abuts against the sample container support part 16, and the bottom of the sample container 2 is driven to vibrate when the sample container support part 16 vibrates, so that the uniform mixing of samples in the sample container 2 is realized. The above-described configurations of the kneading unit and the driving unit are similar to those of the sample kneading apparatus 1 shown in fig. 1, and the configurations of the kneading unit and the driving unit of the sample kneading system 100 may be collectively referred to as the sample kneading apparatus 1.
Now, with continued reference to fig. 4, the anti-play mechanism is a pressing member provided on the conveying portion. Wherein the transport portion may comprise a clamping jaw 8 for clamping the sample container 2, the pressing member being configured as a pressing plate 81 arranged above the clamping jaw. In this example, the sample container 2 is transported from the sample rack to the sample mixing device 1 by the clamping jaws 8 and is pressed against the top of the sample container 2 by the pressure plate 81 during the mixing process, in order to prevent the sample container from moving vertically within the sample container receptacle during the sample mixing process.
The following describes a flow of carrying the sample container 2 between the sample rack and the sample mixing device 1 by the clamping jaws 8 and mixing by pressing the top of the sample container 2 with the pressing plate 81, and describes a state of the anti-play mechanism in the flow with reference to fig. 6 to 10.
As shown in fig. 5, in step S1, the gripping jaw 8 is extended and grips the sample container 2 from the sample rack. In step S2, the gripper lifts the sample container 2 off the sample rack. In step S3, the grip jaw 8 moves horizontally to move the sample container 2 above the sample mixer 1. In step S4, the holding jaw 8 is lowered to place the sample container 2 in the sample mixing apparatus 1, and the pressing plate 81 is positioned above the sample container 2, as shown in fig. 6. In step S5a, jaw 8 is retracted a certain distance a, e.g. moved a certain distance a in the direction Y2 as shown in fig. 7, such that jaw 8 is disengaged from sample container 2, but platen 81 of jaw 8 is still partially above the sample container as shown in fig. 7. In step S5b, the clamping jaw 8 is lowered by a specific distance b relative to the sample mixing device 1, for example, moved by a specific distance b in the Z2 direction as shown in fig. 8, so that the pressing plate 81 lightly presses the top of the sample container 2 as shown in fig. 8. In step S6, the sample kneading apparatus 1 kneads the sample in the sample container 2. In step S6a, the clamping jaw 8 is raised a specific distance c relative to the sample mixing device 1, for example, moved a specific distance c in the direction Z1 opposite to the direction Z2 as shown in fig. 9, so as to disengage the pressure plate 81 from the top of the sample container 2, as shown in fig. 9. Here, the distance b and the distance c may be equal or different, and preferably equal. In step S7, the clamping jaw 8 is extended by a certain distance d, for example, moved by a certain distance d in the direction Y1 opposite to the direction Y2 as shown in fig. 10, so as to clamp the sample container 2 in the sample-mixing apparatus 1 as shown in fig. 10. In step S8, the gripper 8 lifts the sample container 2 off the sample mixing device 1. In step S9, the gripping jaw 8 is moved horizontally, so that the sample container 2 is moved above the sample container holding hole of the sample rack. In step S10, the gripping jaw 8 is lowered to place the sample container 2 into the sample container holding hole of the sample rack. In step S11, the gripping jaws 8 are retracted so as to disengage the sample containers 2 of the sample rack. This completes the mixing operation of the sample container 2.
The above exemplary embodiment shows a process of preventing the sample container from moving when the sample blending system 100 according to the present invention performs sample blending, and the process is to compress and release the sample container by the movement of the clamping jaw. In another implementation, the sample container may be pressed and released by the movement of the sample mixing device. For example, in step S5b, the jaw may be held stationary and raised by a specific distance b along the Z1 direction by the sample mixer. Similarly, in step S6a, the clamping jaw may be kept still and lowered by a specific distance c along the direction Z2 by the sample mixing device. In yet another implementation, the sample container can also be compressed and released by the common movement of the sample mixing device and the clamping jaw. For example, in step S5b, the clamping jaw and the sample mixing device are moved together by a distance b, for example, the clamping jaw is lowered by a distance b1, and the sample mixing device is raised by a distance b2, where b1+ b2 is b. Similarly, in step S6a, the clamping jaw and the sample mixing device are moved away from the moving distance c in the same phase, for example, the clamping jaw is raised by a distance c1, and the sample mixing device is lowered by a distance c2, where c1+ c2 ═ c.
In addition, the sample container is carried by moving the clamping jaws, but the sample container can also be carried by moving the clamping jaws 8 and the sample mixing device 1 together, for example, the clamping jaws 8 move relatively close to and relatively far away from the sample mixing device 1.
It should be noted that in both of the latter two implementations, the sample homogenizing device is required to move to effect compression and release of the sample container by the platen. Based on this, the structure of the sample mixing system 4 can be further improved. The driving part 120 of the sample mixing system 100 may further include a second driving unit and a slider (not shown), for example. Wherein, first backup pad 11 is fixed on the slider, the second drive unit is used for driving the slider drives first backup pad 11 removes to can drive whole mixing portion 110 and remove. In addition, the driving part 120 of the sample mixing system 100 may further include a third supporting plate (not shown) on which a slide rail (not shown) is disposed, and the slide block may move along the slide rail under the driving of the second driving unit. Based on this, the first support plate 11 can be moved, so that the second support plate 12 flexibly connected with the first support plate 11 can be moved, so that the whole mixing part 110 can be moved, thereby enabling the pressing plate 81 to press and release the sample container.
The above description has been made by taking as an example the case where the abutting member is provided in the transporting portion of the sample kneading system according to the present invention. The sample blending system of the example is simple in structure, easy to implement and lowest in cost.
In other implementation manners, according to the utility model discloses a support of sample mixing system spare can also be independent to pressing the device. In one example, the pressing device may be, for example, a moving device that can be moved to the top of the sample container to press against the sample container for mixing after the sample container is placed in the sample container receiving portion and the sample container support portion. In another example, the pressing device may be a non-moving device, for example, and after the sample container is placed in the sample container holding portion and the sample container support portion, the sample container holding portion and the sample container support portion may be moved, for example, such that the sample container moves below the non-moving pressing device, and the sample container is pressed by the non-moving pressing device and mixed. The non-moving pressing means may be, for example, an elastic pressing member.
Further, in other implementations, the anti-play mechanism of the sample blending system according to the present invention may be further configured as a latch mechanism disposed on the sample container support portion, the latch mechanism being used for latching the bottom of the sample container supported on the sample container support portion to prevent the sample container from moving in the vertical direction.
Further, in other implementation manners, according to the utility model discloses a sample mixing system's anti-channeling mechanism can also be constructed as the cylindricality recess of seting up on the sample container supporting part, the bottom sprag of sample container is in the cylindricality recess to prevent this sample container along vertical direction drunkenness. In this embodiment, the bottom of the cylindrical recess is of a planar configuration, rather than the curved configuration shown in FIG. 2, so that the bottom of the sample container is not subjected to a vertically upward force, thereby causing the sample container to float vertically up and down.
Further, according to the utility model discloses a sample mixing system can also include the sensor that is used for detecting the motion state of sample container supporting part, for example correlation formula photoelectric sensor, reflection type photoelectric sensor, hall sensor, capacitive sensor, preferably correlation formula photoelectric sensor.
Further, according to the utility model discloses a sample mixing system can also include the controlling means who is used for with drive division communication connection and control the action of drive division. The control device may be any device capable of issuing control instructions, such as a microcontroller or the like. The communication connection includes a wireless communication connection, such as a WIFI connection, and a wired communication connection, such as a direct connection through a USB interface or a network port.
Further, the sensor that the sample mixing system mentioned in the foregoing can include according to the utility model discloses a sensor can also with controlling means communication connection to transmit the motion state of the sample container supporting part that detects for controlling means, controlling means can adjust the drive parameter of drive part or can judge whether the motion state of sample container supporting part or drive part breaks down according to the motion state of sample container supporting part.
The above exemplarily illustrates the sample blending system provided according to an aspect of the present invention. The sample mixing system has the anti-moving mechanism for preventing the sample container from moving along the vertical direction in the sample mixing process, so that the sample can be prevented from splashing, liquid particles are adhered to the inner wall of the container to cause influence on the measuring result, and the bar code on the outer wall of the sample container can be prevented from being abraded.
According to the utility model discloses an on the other hand still provides a sample mixing system, sample mixing system is arranged in the sample of mixing sample container and includes: the blending part is provided with a sample container accommodating part for accommodating a sample container and a sample container supporting part for supporting the bottom of the sample container, wherein a cylindrical groove is formed in the sample container supporting part, and the bottom of the sample container is supported in the cylindrical groove; and the driving part is used for driving the sample container supporting part to move so as to drive the bottom of the sample container to move, so that the samples in the sample container are uniformly mixed. In this embodiment, the bottom of the cylindrical groove is a planar structure, rather than the curved surface structure shown in fig. 2, so that the bottom of the sample container is not subjected to a vertical upward force, and thus the sample container is not caused to move vertically up and down, and further the sample can be prevented from splashing, so that liquid particles are adhered to the inner wall of the container to cause influence on the measurement result, and the bar code on the outer wall of the sample container can be prevented from being worn.
According to a further aspect of the present invention, there is provided a sample analyzer 1000, as shown in fig. 11, the sample analyzer 1000 may include an analysis portion 200 and the sample blending system 100 described in the foregoing, wherein the analysis portion 200 is used for analyzing the blended sample in the sample container. Furthermore, the sample analyzer may further include a transport portion 300 for transporting the sample container 2 out of the sample rack 9 and into the sample container accommodating portion of the sample mixing system 100 and abutting the bottom of the sample container on the sample container support portion. Here, the transport portion 300 may include a gripping jaw 8 to carry the sample container 2 between the sample rack 9 and the sample mixing device 1. Further, a pressing plate 81 is disposed on the clamping jaw 8 of the conveying part 300, and the pressing plate 81 can be pressed against the top of the sample container as a movement prevention mechanism in the sample mixing process to prevent the sample container from moving in the vertical direction. Alternatively, the anti-tamper mechanism may be another independent pressing member. The pressing member may be moving or non-moving. Furthermore, the pressing member may be an elastic member. Alternatively, the anti-play mechanism may also be a latch mechanism on the sample container support for latching the bottom of a sample container supported on said sample container support to prevent play of the sample container in the vertical direction. Alternatively, the anti-moving mechanism may be a cylindrical groove formed in the sample container support part, and the bottom of the sample container is supported in the cylindrical groove to prevent the sample container from moving in the vertical direction.
Furthermore, the sample analyzer 1000 may further comprise a sample transport device 400, wherein the sample transport device 4000 enables loading, lateral transportation and unloading actions of the sample rack 9 to enable automatic batch measurement of peripheral blood.
The analysis section 200 may include a code scanner (not shown) provided at the code scanning bits and a sampling device (not shown) provided at the sampling bits, and may further include a detection device (not shown). Wherein, the code scanner is used for reading the identification part information (such as a bar code label) on the code scanning bit sample container. Illustratively, the scanner may be a bar code recognizer, a two-dimensional code recognizer, a Radio Frequency Identification (RFID) tag reader, or the like, and may also be a combination of a camera that acquires identification part information by taking an image and then image-processing the image and a soft recognition algorithm. The sampling device is used for sucking the sample in the sample container at the sampling position, and the detection device is used for detecting the sample sucked by the sampling device.
Furthermore, in a further embodiment of the present invention, the sample analyzer 1000 may further comprise a blending device (not shown) for blending the venous blood sample, and the aforementioned sample blending system in the sample analyzer is used for blending the peripheral blood sample. In this embodiment, the sample analyzer can mix and analyze both peripheral blood samples and venous blood samples. The sample analyzer may perform venous blood blending or peripheral blood blending based on user selection; alternatively, the sample analyzer may automatically identify whether venous or peripheral blood blending is required. Preferably, in case sample analyzer 1000 comprises a transport portion 300 with a clamping jaw 8, this clamping jaw may simultaneously serve as a mixing device for mixing the venous blood sample.
The foregoing is illustrative of a sample analyzer provided in accordance with yet another aspect of the present invention. According to the utility model discloses a sample analyzer has the anti-channeling mechanism that prevents sample container at sample mixing in-process along vertical direction drunkenness, not only can prevent that the sample from splashing and play the liquid particle adhesion and cause the influence to measuring result on the container inner wall, can also prevent the bar code on the sample container outer wall of wearing and tearing.
Although the example embodiments have been described herein with reference to the accompanying drawings, it is to be understood that the above-described example embodiments are merely illustrative and are not intended to limit the scope of the present invention thereto. Various changes and modifications may be effected therein by one of ordinary skill in the pertinent art without departing from the scope or spirit of the present invention. All such changes and modifications are intended to be included within the scope of the present invention as claimed in the appended claims.
It will be understood by those skilled in the art that all of the features disclosed in this specification (including any accompanying claims, abstract and drawings), and all of the processes or elements of any method or apparatus so disclosed, may be combined in any combination, except combinations where such features are mutually exclusive. Each feature disclosed in this specification (including any accompanying claims, abstract and drawings) may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise.
Furthermore, those skilled in the art will appreciate that while some embodiments described herein include some features included in other embodiments, rather than other features, combinations of features of different embodiments are meant to be within the scope of the invention and form different embodiments. For example, in the claims, any of the claimed embodiments may be used in any combination.

Claims (19)

1. A sample blending system for blending a sample in a sample container, comprising:
a kneading unit having a sample container accommodating unit for accommodating a sample container and a sample container supporting unit for supporting the bottom of the sample container;
the driving part is used for driving the sample container supporting part to move so as to drive the bottom of the sample container to move, so that the sample in the sample container is uniformly mixed;
and the anti-shifting mechanism is used for preventing the sample container from shifting in the vertical direction in the sample container accommodating part in the sample blending process.
2. The sample blending system according to claim 1, wherein the anti-play mechanism is configured as a pressing part which can press against the top of the sample container accommodated in the sample container accommodating part to prevent the sample container from moving in a vertical direction.
3. The sample mixing system of claim 2, wherein the biasing member is configured to be resilient.
4. The sample blending system of claim 2, wherein the pressure member is movable or immovable relative to the blending portion.
5. The sample blending system of claim 4, wherein a height of the pressing member is adjustable relative to the blending portion.
6. The sample mixing system according to claim 2, further comprising a transport portion for transporting a sample container into the sample container accommodating portion and causing a bottom portion of the sample container to abut on the sample container supporting portion, wherein the abutting member is provided on the transport portion.
7. The sample blending system according to claim 6, wherein the transport portion comprises a jaw for holding a sample container, and the pressing member is configured as a platen disposed above the jaw.
8. The sample blending system according to claim 1, wherein the anti-play mechanism is configured as a latch mechanism provided on the sample container support for latching a bottom of a sample container supportable on the sample container support to prevent the sample container from moving in a vertical direction.
9. The sample mixing system according to claim 1, wherein the anti-play mechanism is configured as a cylindrical groove formed in the sample container support portion, and the bottom of the sample container is supported in the cylindrical groove.
10. The sample blending system according to any one of claims 1 to 9, wherein the driving part comprises a first driving unit and an eccentric mass which are connected with each other, and the first driving unit drives the eccentric mass to rotate, so as to drive the sample container support part and the bottom of the sample container supported on the sample container support part to swing, so as to blend the sample in the sample container.
11. The sample mixing system according to claim 10, wherein the mixing section comprises a first support plate, a flexible connecting member, and a second support plate, wherein a sample container fixing hole is formed in the first support plate as the sample container accommodating section, the second support plate is connected to the first support plate through the flexible connecting member, and the first driving unit and the sample container supporting section are fixed to the second support plate.
12. The sample blending system according to claim 11, wherein the flexible connecting member comprises a flexible post or spring.
13. The sample mixing system of claim 10, wherein the first drive unit is configured as a stepper motor, a dc motor, or a servo motor.
14. The sample mixing system according to claim 11, wherein the driving unit further comprises a second driving unit and a sliding block, the first support plate is fixed on the sliding block, and the second driving unit is configured to drive the sliding block to drive the first support plate to move.
15. The sample mixing system according to claim 14, wherein the driving unit further comprises a third support plate, a slide rail is disposed on the third support plate, and the slide block can move along the slide rail under the driving of the second driving unit.
16. The sample mixing system of any one of claims 1-9, further comprising a sensor for detecting a state of motion of the sample container support.
17. A sample blending system for blending a sample in a sample container, comprising:
the blending part is provided with a sample container accommodating part for accommodating a sample container and a sample container supporting part for supporting the bottom of the sample container, wherein a cylindrical groove is formed in the sample container supporting part, and the bottom of the sample container is supported in the cylindrical groove;
and the driving part is used for driving the sample container supporting part to move so as to drive the bottom of the sample container to move, so that the samples in the sample container are uniformly mixed.
18. A sample analyzer comprising an analysis section for analyzing a homogenized sample in a sample container, and a sample homogenizing system according to any one of claims 1 to 17.
19. The sample analyzer of claim 18, further comprising a blending device for blending a venous blood sample, and the sample blending system is configured to blend a peripheral blood sample.
CN201920776719.2U 2019-05-27 2019-05-27 Sample blending system and sample analyzer Active CN210923234U (en)

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Application Number Priority Date Filing Date Title
CN201920776719.2U CN210923234U (en) 2019-05-27 2019-05-27 Sample blending system and sample analyzer

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