CN210871549U - Noninvasive blood vessel endothelium function diagnostic instrument - Google Patents
Noninvasive blood vessel endothelium function diagnostic instrument Download PDFInfo
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- CN210871549U CN210871549U CN201920639907.0U CN201920639907U CN210871549U CN 210871549 U CN210871549 U CN 210871549U CN 201920639907 U CN201920639907 U CN 201920639907U CN 210871549 U CN210871549 U CN 210871549U
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Abstract
The utility model discloses a noninvasive blood vessel endothelium function diagnostic apparatus, including the diagnostic apparatus host computer, be equipped with induced temperature measurement module on the diagnostic apparatus host computer, physiological signal detection module and display module, be equipped with microprocessor in the diagnostic apparatus host computer, physiological signal detection module includes blood pressure test unit and blood oxygen detecting element, and microprocessor's input and display module's input are connected respectively to microprocessor's output, and microprocessor's input is all connected to induced temperature measurement module's output, blood pressure detecting element's output and blood oxygen detecting element's output. The utility model discloses utilize induced reactivity congestion principle, do not use the beam arm mode, and carry out cold/hot stimulation induction through induced temperature measurement module, through the temperature variation signal that detects small tip blood vessel, cooperation microprocessor and physiological signal detection module show testing result through the display module, have improved the accuracy and have reduced the cost, but wide application in medical equipment technical field.
Description
Technical Field
The utility model belongs to the technical field of the medical instrument technique and specifically relates to a do not have vascular endothelial function diagnostic equipment that creates.
Background
The endothelial layer is a single cell layer covering the inner surface of blood vessels, not only is the permeability barrier of the blood vessels, but also is a multifunctional paracrine and endocrine organ, endothelial dysfunction is closely related to various diseases, including diabetes, hypertension, stroke and the like, and is frequently generated in the early and treatable stages of cardiovascular events, and normal vascular endothelial function is the basic condition for maintaining the homeostasis of the cardiovascular system. Timely detection of vascular endothelial dysfunction for early intervention and treatment to reverse vascular disease is critical to maintaining cardiovascular health, reducing the incidence of cardiovascular disease and medical costs. Compared with an invasive detection method, the noninvasive endothelial function detection equipment has the advantages of convenient detection, capability of preventing or reducing the wound of a patient and better clinical application prospect.
At present, the vascular endothelial function detection method based on the concept of arm ischemia induced reactive hyperemia is gradually accepted by the industry, and is gradually applied to a plurality of fields of cardiovascular diseases, diabetes, nephropathy, andropathy and the like. The current clinical application of noninvasive vascular endothelial function detection equipment is mainly to observe the change of the inner diameter of a blood vessel before and after reactive hyperemia by pressurizing and blocking brachial artery, and an endothelial function diagnostic instrument based on the concept occupies a market leading position.
The non-invasive blood vessel endothelium function detection equipment which is developed based on ultrasound and peripheral tension technology and is introduced abroad and clinically applied at present at home and abroad is used for detecting the change of the inner diameter of a blood vessel before and after congestion or the change of the amplitude of a fingertip pulse wave based on arm ischemia-induced reactive congestion; the non-invasive vascular endothelial function diagnostic instrument developed by utilizing fingertip thermal monitoring (DTM) technology is based on the measurement principle that brachial artery is blocked by a bundle arm, and the recovery condition of fingertip temperature after reactive hyperemia is observed. In fact, the arm restraints adopted by the above-mentioned technologies can cause ischemia and hypoxia of forearms and hands of human bodies, easily cause discomfort of human bodies after too long time, and are expensive and high in detection cost, and the evaluation result is influenced by various factors and is not high in accuracy.
SUMMERY OF THE UTILITY MODEL
In view of this, the embodiment of the present invention provides a noninvasive diagnosis instrument for vascular endothelial function with low cost and high accuracy.
The embodiment of the utility model provides a there is not vascular endothelial function diagnostic apparatus of wound, including the diagnostic apparatus host computer, be equipped with induced temperature measurement module, physiological signal detection module and display module on the diagnostic apparatus host computer, be equipped with microprocessor in the diagnostic apparatus host computer, physiological signal detection module includes blood pressure test unit and blood oxygen detecting element, microprocessor's input and display module's input are connected respectively to microprocessor's output, microprocessor's input is all connected to induced temperature measurement module's output, blood pressure detecting element's output and blood oxygen detecting element's output.
Further, a key module, a power module and an alarm module are further arranged on the main machine of the diagnostic instrument, the output end of the key module is connected with the input end of the microprocessor, the output end of the power module is respectively connected with the input end of the induced temperature measurement module and the input end of the microprocessor, and the input end of the alarm module is connected with the output end of the microprocessor.
Furthermore, a storage module is further arranged in the diagnostic instrument host, the input end of the storage module is connected with the output end of the microprocessor, and the output end of the storage module is connected with the input end of the microprocessor.
Furthermore, a blood pressure measuring interface and a blood oxygen measuring interface are arranged on the side surface of the main machine of the diagnostic apparatus.
Further, the side surface of the diagnostic instrument host is provided with an SD card slot.
Further, the induced temperature measurement module comprises a temperature sensor and a PTC refrigeration piece, the temperature sensor is arranged above the PTC refrigeration piece, the input end of the PTC refrigeration piece is connected with the output end of the microprocessor, and the output end of the temperature sensor is connected with the input end of the microprocessor.
Furthermore, heat insulation cotton is arranged between the temperature sensor and the PTC refrigerating sheet.
Furthermore, a heat dissipation window is arranged on the rear cover of the induced temperature measurement module.
Furthermore, a concave finger pad and an elastic rubber finger cover are arranged on the induced temperature measurement module.
Furthermore, the shape of the concave finger belly is fitted with the shape of a finger, and the elastic rubber finger cover is detachably arranged on the induced temperature measurement module; the concave finger belly is filled with heat insulation cotton except for the temperature sensor and the PTC refrigerating sheet which are arranged in the center, and the other parts of the concave finger belly and the PTC refrigerating sheet are filled with heat conduction materials.
Above-mentioned the utility model discloses technical scheme in the embodiment has following advantage: the embodiment of the utility model comprises a diagnostic apparatus host, wherein the diagnostic apparatus host is provided with an induced temperature measurement module, a physiological signal detection module and a display module, the diagnostic apparatus host is internally provided with a microprocessor, and the physiological signal detection module comprises a blood pressure detection unit and a blood oxygen detection unit; compare in current beam arm formula detection method, the utility model discloses utilize induced reactivity congestion principle, do not use beam arm mode, and carry out cold/hot stimulation induction through induced temperature measurement module, through the temperature change signal that detects small tip blood vessel, cooperation microprocessor and physiological signal detection module show the testing result through the display module, have improved the accuracy and the cost is reduced.
Drawings
Fig. 1 is a block diagram of the overall structure of a non-invasive diagnosis instrument for endothelial function of blood vessels;
fig. 2 is a schematic structural diagram of a main unit of the diagnostic apparatus according to an embodiment of the present invention;
fig. 3 is a schematic structural diagram of an induced temperature measurement module according to an embodiment of the present invention;
fig. 4 is a schematic structural diagram of a rear cover of the induced temperature measurement module according to the embodiment of the present invention;
fig. 5 is a first circuit schematic diagram of an embodiment of the present invention;
fig. 6 is a second circuit schematic diagram according to an embodiment of the present invention.
Detailed Description
Referring to fig. 1, the embodiment of the utility model provides a there is not vascular endothelial function diagnostic apparatus of wound, including the diagnostic apparatus host computer, be equipped with induced temperature measurement module, physiological signal detection module and display module on the diagnostic apparatus host computer, be equipped with microprocessor in the diagnostic apparatus host computer, physiological signal detection module includes blood pressure test unit and blood oxygen detecting element, microprocessor's output is connected the input of induced temperature measurement module and display module's input respectively, microprocessor's input is all connected to the output of induced temperature measurement module, blood pressure detecting element's output and blood oxygen detecting element's output.
The temperature measurement module adopts a thermistor, a signal conditioning circuit and AD conversion to realize high-precision and high-stability temperature detection, and is connected with the microprocessor through a USB wire.
The physiological signal detection module is used for reserving an interface for host equipment, can be externally connected with independent detection devices such as blood pressure and blood oxygen, realizes the change monitoring of important vital sign parameters in the vascular endothelial function detection process, can prevent accidents by emergently stopping the test in special cases, and is safe and reliable.
The microprocessor of the embodiment is an embedded system main control unit and is used for triggering signals, the pulse width modulation mode is used for controlling the on-off of the high-power MOS field effect transistor so as to control the frequency and amplitude of stimulation of the induction module, the accurate control of the temperature of the induction module is realized, the temperature of the induction module is ensured to be constant at a target value, the constant temperature is well realized within the detection set time, and an overheating protection circuit and a light alarm circuit are arranged. The microprocessor receives the temperature detection signal sent by the induced temperature measurement module and the detection signal sent by the physiological signal detection module, triggers a corresponding control signal, and then sends the control signal to the display module and the like for control. The utility model discloses a microprocessor does not relate to the improvement of data processing process, and its signal trigger process can adopt current MCU to realize.
And the display module is used for displaying the temperature change and the detection result of the peripheral blood vessel in real time according to the control signal of the microprocessor. The display module can be realized by adopting the existing liquid crystal display, and can be connected with the microprocessor through a USB interface.
And the blood pressure detection unit is used for acquiring the blood pressure signal of the user in the blood vessel endothelium function detection process in real time. The blood pressure detection unit can be realized by adopting an existing sphygmomanometer.
And the blood oxygen detection unit is used for acquiring the blood oxygen signal of the user in the blood vessel endothelium function detection process in real time. The blood oxygen detecting unit can be realized by adopting the existing blood oxygen detector.
Referring to fig. 1, as a further preferred embodiment, the main unit of the diagnostic apparatus is further provided with a key module, a power module and an alarm module, an output end of the key module is connected to an input end of the microprocessor, an output end of the power module is respectively connected to an input end of the induced temperature measurement module and an input end of the microprocessor, and an input end of the alarm module is connected to an output end of the microprocessor.
The key module is used for acquiring a control input signal of a user. The key module can be realized by adopting a three-gear toggle switch.
The power supply module is used for converting 220V commercial power into 12V direct current power through the power adapter to supply power for the induced temperature measurement module and realize that the refrigeration of the refrigeration piece is carried out to a set temperature (the refrigeration is carried out to 5 ℃); 12V direct current voltage is converted into 9V through the voltage stabilizing chip L7809 to supply power for the induction temperature measuring module to heat, the refrigerating piece is heated to a set temperature (heated to 40 ℃), and 5V direct current voltage is converted into 5V direct current voltage through the voltage stabilizing chip L7805 to supply power for the microprocessor.
And the alarm module is used for carrying out alarm prompt according to the control signal of the microprocessor. When the body of a user is untimely in the vascular endothelial function detection process, the system can give an alarm in time and stop the vascular endothelial function detection process, and the safety is high.
As shown in fig. 2, in the structure of the main unit of the diagnostic apparatus of the present embodiment, the specific reference numerals are as follows: 1 represents an induction and temperature measurement interface; 2 represents an induction mode; 3 represents external blood pressure measurement; 4 represents a temperature profile; 5 represents external oximetry; 6 represents a built-in SD card; 7 represents a stimulus selection toggle switch; 8 represents an emergency stop key; 9 represents a status indicator light; 10 represents a switch; 11 represents a power supply interface; 12 represents the measurement result display; and 13 represents a power indicator lamp.
The key, display and alarm module of this embodiment includes 1 switch button 10, 1 three keep off toggle switch 7, 1 emergency stop test button 8, 1 monochromatic lamp, 1 double-colored LED lamp 9, a model is the LCD screen of LCD 12864. In fig. 2, the power button 10 is used to implement power on/off (short-press power on, long-press 3s power off); the stimulation selection key 7 is a three-gear toggle switch, so that the hot stimulation is added in the left 1 gear, the cold stimulation is added in the left 2 gear, and no toggle indicates no stimulation is added; the monochromatic lamp is used for displaying the starting state (red), the bicolor lamp 9 is used for displaying the thermal stimulation state (green), the cold stimulation state (red and green alternate flashing) and the abnormal alarm state (red flashing); the liquid crystal screen is used for displaying the temperature curve 4 and the detection diagnosis result 12 in real time.
As shown in fig. 2, the diagnostic device host of the present embodiment is further provided with 1 16G custodon SD card 6 for storing data; the blood pressure meter interface 3 and the oximeter interface 5, the external port collects blood pressure and blood oxygen for monitoring, so as to prevent the body abnormality of the tested person (when the detected blood pressure diastolic pressure is lower than 50mmHg or systolic pressure is higher than 140mmHg or blood oxygen is lower than 90%) from stopping the test in an emergency, so as to ensure life safety.
Referring to fig. 1, as a further preferred embodiment, a storage module is further provided in the diagnostic apparatus host, an input end of the storage module is connected to an output end of the microprocessor, and an output end of the storage module is connected to an input end of the microprocessor.
In the memory module of the embodiment, 1 16G gold morton SD card stores data. The temperature detected by the microprocessor is displayed in real time and written into the SD card for storage, and the collected data can be used for subsequent scientific research.
Referring to fig. 2, further as a preferred embodiment, the diagnostic apparatus main body is provided with a blood pressure measuring interface 3 and an blood oxygen measuring interface 5 on the side surface.
Referring to fig. 2, in a further preferred embodiment, an SD card slot 6 is provided on the side surface of the diagnostic apparatus main body.
Further as a preferred embodiment, the induced temperature measurement module comprises a temperature sensor and a PTC refrigeration piece, the temperature sensor is arranged above the PTC refrigeration piece, the input end of the PTC refrigeration piece is connected with the output end of the microprocessor, and the output end of the temperature sensor is connected with the input end of the microprocessor.
In the structural schematic diagram of the induced temperature measurement module in fig. 3 of this embodiment, the meanings of the respective reference numerals are as follows: 1 represents a temperature sensor; 2 represents a finger cover; 3 represents an induction and temperature measurement interface; 4 represents the thumb belly; 5 represents heat preservation cotton; and 6 represents a semiconductor refrigerating sheet.
As shown in fig. 3, in the induced temperature measurement module of this embodiment, 1 NTC patch thermistor (080510K) is used as a temperature sensor 1 for detecting temperature and feeding back to a microprocessor, and a PTC refrigeration sheet 6 is used as a heating and refrigeration element. The temperature sensor 1 is arranged above a central refrigerating sheet 6 of the induction temperature measuring module, and heat insulation cotton 5 is stuck between the temperature sensor and the refrigerating sheet so as to insulate heat and provide comfort; the inducing stimulation is controlled by the microprocessor sending out control signals. The embodiment is fixedly connected with the diagnostic instrument host through the induction and temperature measurement interface 3.
In addition, as shown in fig. 3, in order to provide a good heat preservation effect for the fingertip to be detected and ensure uniform temperature distribution and a good detection effect, the embodiment is provided with a concave finger pad 4 which is fitted to the finger shape and a detachable elastic rubber finger cover 2, wherein a space between the concave finger pad 4 and the refrigeration sheet 6 (including the periphery of the heat preservation cotton) is filled with a good heat conduction material.
In addition, as shown in fig. 5 and fig. 6, the specific working principle of the induced temperature measurement module of the present embodiment is as follows:
in the embodiment, after a power-on key of the power supply of the equipment is switched on, the power lamp is turned on to be red, and the microprocessor is initialized to prompt a tester to input basic information; then controlling a temperature sensor to acquire temperature data, blood pressure and blood oxygen information, amplifying and filtering in real time, and storing in a storage SD card and displaying on a display screen; the microprocessor controls the on-off of the double-color lamp D1 and the triode Q4 according to the blood pressure signal and the blood oxygen signal, namely the on-off of the alarm circuit, if the blood pressure and the blood oxygen of the user are abnormal, the alarm circuit is continuously and alternately switched on and off, so that the red lamp flickers to prompt the emergency stop test (the emergency stop test is controlled by an emergency stop test key in the embodiment); after testing for 6 minutes in a normal state, the microprocessor sends a selective induction mode to the display screen, and after the tester selects the selective induction mode, the microprocessor induces the selective induction mode to be added for testing; specifically, if the stimulation is thermal, the MOS tube Q1 is turned on, Q2 is turned off, and Q3 is turned on; if the stimulation is cold, the MOS tube Q1 is disconnected, the Q2 is connected, the Q3 and the Q4 are alternately connected at the same time, the automatic removal is induced after about 8 minutes, the condition of the peripheral temperature recovery of the tiny blood vessel is observed after waiting for 10 minutes at most, and meanwhile the microprocessor controls the display screen to display the result.
As shown in fig. 4, in order to realize a good cooling function, the rear cover in the present embodiment is provided with a heat radiation window 7.
As shown in fig. 3, in a further preferred embodiment, a piece of thermal insulation cotton 5 is arranged between the temperature sensor and the PTC refrigeration sheet.
As shown in fig. 4, in a further preferred embodiment, a heat dissipation window 7 is disposed on the rear cover of the induced temperature measurement module.
As shown in fig. 3, further as a preferred embodiment, the temperature-sensing module is provided with a concave finger pad 4 and an elastic rubber finger cover 2.
As shown in fig. 3, as a further preferred embodiment, the shape of the concave finger pad 4 is fitted to the shape of a finger, and the elastic rubber finger cover 2 is detachably disposed on the induced temperature measurement module; the concave finger pad 4 is filled with heat insulation cotton except for the temperature sensor and the PTC refrigerating sheet 6 which are arranged in the center, and the other parts of the concave finger pad and the PTC refrigerating sheet 6 are filled with heat conduction materials.
The utility model discloses a do not have vascular endothelial function diagnostic equipment's working process as follows:
firstly, the device starts to collect data after being started, the data comprises basic information of a tester, such as name, age, sex, input of medical history basic conditions, blood pressure, blood oxygen, detection temperature of tiny blood vessel ends and the like, whether blood pressure and blood oxygen of a human body are abnormal or not is monitored through preset safe blood pressure and blood oxygen, meanwhile, the temperature data is collected, and then collected related signals are stored in a storage module so as to be convenient for diagnosing the function of vascular endothelium according to the signals.
In the using process, a user firstly sleeves a finger cover into a main machine for fixing, connects a main machine power supply of the noninvasive blood vessel function instrument, connects a blood pressure, blood oxygen and induction temperature measuring module, puts a left index finger into a space between a concave finger belly and an elastic rubber finger cover, switches on the main machine power supply, displays red by a monochromatic lamp, selectively inserts whether to be inserted into the measurement according to prompting input basic information, if the measurement result is inserted into the measurement module, the main machine prompts to select an induction mode by detecting at normal temperature for 6mins, selects heat or cold stimulation by a three-gear toggle switch, changes the states of the two-color lamp (heat is green, cold is red and green and flickers alternately), indicates that induction is added, and displays the temperature change of the finger tip in real time; when the set temperature is reached for a period of time, the stimulation is automatically switched off after about 8mins, the two-color lamp returns to an off state, the finger temperature is measured at the normal temperature and changes to be constant, the measurement is finished after about 10mins, a trend curve of the whole measurement process can be displayed on a display screen, meanwhile, the whole diagnosis result is displayed, the measurement is finished, if abnormal two-color lamps appear in the measurement process, the two-color lamp can flash red to give an alarm, and the emergency stop test key can be pressed to stop the test.
To sum up, the utility model discloses utilize the hyperemia principle of induced reactivity, adopt to induce cold/thermal stimulation to small tip blood vessel, can detect small tip vascular temperature variation, reduced the interference of other regulation activities and noise, more directly perceived accurate reflection vascular endothelial function. The developed equipment has the advantages of accurate measurement, small volume, low cost, good stability, portability in detection and the like. Compare with current vascular endothelial function diagnostic technique and clinical application product, the utility model discloses avoided current use to restraint arm mode and realized that reactive congestion can cause human forearm and hand ischemia, oxygen deficiency, the time overlength makes the human health produce discomfort easily, product price is expensive moreover, detects problem such as with high costs.
While the preferred embodiments of the present invention have been described, the present invention is not limited to the above embodiments, and those skilled in the art can make various equivalent modifications or substitutions without departing from the spirit of the present invention, and such equivalent modifications or substitutions are intended to be included within the scope of the present invention as defined by the appended claims.
Claims (10)
1. A noninvasive diagnosis instrument for vascular endothelial function is characterized in that: the blood pressure detection device comprises a diagnostic apparatus host, wherein an induced temperature measurement module, a physiological signal detection module and a display module are arranged on the diagnostic apparatus host, a microprocessor is arranged in the diagnostic apparatus host, the physiological signal detection module comprises a blood pressure detection unit and a blood oxygen detection unit, the output end of the microprocessor is respectively connected with the input end of the induced temperature measurement module and the input end of the display module, and the output end of the induced temperature measurement module, the output end of the blood pressure detection unit and the output end of the blood oxygen detection unit are all connected with the input end of the microprocessor.
2. The non-invasive diagnosis instrument for endothelial function of blood vessel according to claim 1, wherein: the diagnostic instrument host is also provided with a key module, a power module and an alarm module, wherein the output end of the key module is connected with the input end of the microprocessor, the output end of the power module is respectively connected with the input end of the induced temperature measurement module and the input end of the microprocessor, and the input end of the alarm module is connected with the output end of the microprocessor.
3. The non-invasive diagnosis instrument for endothelial function of blood vessel according to claim 1, wherein: the diagnostic instrument host is also internally provided with a storage module, the input end of the storage module is connected with the output end of the microprocessor, and the output end of the storage module is connected with the input end of the microprocessor.
4. The non-invasive diagnosis instrument for endothelial function of blood vessel according to claim 1, wherein: the side surface of the main machine of the diagnostic apparatus is provided with a blood pressure measuring interface and a blood oxygen measuring interface.
5. The non-invasive diagnosis instrument for endothelial function of blood vessel according to claim 1, wherein: the side surface of the diagnostic instrument host is provided with an SD card slot.
6. The non-invasive diagnosis instrument for endothelial function of blood vessel according to claim 1, wherein: the temperature induction and measurement module comprises a temperature sensor and a PTC refrigeration piece, the temperature sensor is arranged above the PTC refrigeration piece, the input end of the PTC refrigeration piece is connected with the output end of the microprocessor, and the output end of the temperature sensor is connected with the input end of the microprocessor.
7. The non-invasive diagnostic apparatus for vascular endothelial function according to claim 6, wherein: and heat insulation cotton is arranged between the temperature sensor and the PTC refrigerating sheet.
8. The non-invasive diagnostic apparatus for vascular endothelial function according to claim 6, wherein: and a heat dissipation window is arranged on the rear cover of the induced temperature measurement module.
9. The non-invasive diagnostic apparatus for vascular endothelial function according to claim 6, wherein: the induction temperature measuring module is provided with a concave finger pad and an elastic rubber finger cover.
10. The non-invasive diagnostic apparatus for vascular endothelial function according to claim 9, wherein: the shape of the concave finger belly is fitted with the shape of a finger, and the elastic rubber finger cover is detachably arranged on the induction temperature measuring module; the concave finger belly is filled with heat insulation cotton except for the temperature sensor and the PTC refrigerating sheet which are arranged in the center, and the other parts of the concave finger belly and the PTC refrigerating sheet are filled with heat conduction materials.
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| CN201920639907.0U CN210871549U (en) | 2019-05-05 | 2019-05-05 | Noninvasive blood vessel endothelium function diagnostic instrument |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112494006A (en) * | 2020-10-12 | 2021-03-16 | 上海光电医用电子仪器有限公司 | Vital sign monitoring device, system and method |
| CN112674749A (en) * | 2020-12-03 | 2021-04-20 | 广东省医疗器械研究所 | Non-invasive testing system for peripheral blood vessel regulation function and implementation method thereof |
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2019
- 2019-05-05 CN CN201920639907.0U patent/CN210871549U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112494006A (en) * | 2020-10-12 | 2021-03-16 | 上海光电医用电子仪器有限公司 | Vital sign monitoring device, system and method |
| CN112674749A (en) * | 2020-12-03 | 2021-04-20 | 广东省医疗器械研究所 | Non-invasive testing system for peripheral blood vessel regulation function and implementation method thereof |
| CN112674749B (en) * | 2020-12-03 | 2024-04-19 | 广东省医疗器械研究所 | Noninvasive test system for peripheral vascular regulating function and implementation method thereof |
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