CN210775430U - Absorption cell structure of medicine absorption sampling system - Google Patents
Absorption cell structure of medicine absorption sampling system Download PDFInfo
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- CN210775430U CN210775430U CN201920538194.9U CN201920538194U CN210775430U CN 210775430 U CN210775430 U CN 210775430U CN 201920538194 U CN201920538194 U CN 201920538194U CN 210775430 U CN210775430 U CN 210775430U
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Abstract
An absorption tank structure of a drug absorption sampling system is characterized in that a permeation film is arranged in the middle of the absorption tank, one side of the permeation film is a mother liquor cavity, and the other side of the permeation film is an absorption cavity; a mother liquid outlet is formed in the top of the mother liquid cavity, a mother liquid inlet is formed in the bottom of the mother liquid cavity, and the mother liquid outlet is formed in the bottom of the mother liquid cavity; the top of the absorption cavity is provided with a liquid guide port, and one side of the bottom of the absorption cavity is provided with a solvent inlet and a solvent outlet. The stirring rod is driven to rotate under the action of magnetic force, so that the stirring rod rotates in the absorption cavity, the flow of blood in the human body is simulated, the experiment is facilitated, and the using effect is good.
Description
Technical Field
The utility model belongs to the technical field of medical experimental facilities uses, especially a medicine absorbs absorption cell structure of sampling system.
Background
The oral preparation is a common preparation form, the precondition of the oral medicine for exerting the drug effect is that the medicine is released and absorbed by the gastrointestinal tract to enter the body for exerting the pharmacological action (except the medicine which directly exerts the action on the gastrointestinal tract), and the evaluation of the release and the absorption of the medicine is very important content of the oral preparation. In order to simulate the release and absorption of drugs in the gastrointestinal tract (e.g. the intestinal tract), some biomimetic systems have been developed in the prior art. For example, chinese utility model patent No. 201110280230.4 provides a drug absorption apparatus. The absorption tank of the absorption instrument is simple in structure, and the characteristic of intestinal tracts inside a human body cannot be well simulated, so that the experimental effect is influenced.
SUMMERY OF THE UTILITY MODEL
In order to solve the existing problem, the utility model discloses an absorption cell structure of medicine absorption sampling system, its concrete technical scheme as follows:
an absorption tank structure of a drug absorption sampling system is characterized in that a permeation film is arranged in the middle of the absorption tank, one side of the permeation film is a mother liquor cavity, and the other side of the permeation film is an absorption cavity; a mother liquid outlet is formed in the top of the mother liquid cavity, a mother liquid inlet is formed in the bottom of the mother liquid cavity, and the mother liquid outlet is formed in the bottom of the mother liquid cavity; the top of the absorption cavity is provided with a liquid guide port, and one side of the bottom of the absorption cavity is provided with a solvent inlet and a solvent outlet.
Further, still include the heat preservation system, the heat preservation system includes heating piece and absorption cell fixation clamp, the absorption cell passes through the absorption cell fixation clamp to be fixed between the heating piece, and the heating piece heats the heat preservation to the absorption cell.
Furthermore, two silica gel blank holders are arranged between the mother liquor cavity and the absorption cavity of the absorption tank, and the permeable film is pressed between the two silica gel blank holders, so that the permeable film is vertically fixed inside the absorption tank; the mother liquid outlet, the mother liquid inlet and the solvent inlet and outlet are luer joints; the liquid guide port is a screwed joint, and a stirrer is arranged in the absorption cavity;
the absorption tank bottom still is provided with stirring son rotary device, stirring son rotary device includes driving motor, driving pulley, driving belt, belt pivot and magnet rotor, driving motor connects driving pulley, and the driving belt that registrates between driving pulley and the belt runner realizes the transmission through the belt, and the magnet rotor is connected at belt pivot top, and the magnet rotor is located stirring son below position.
The device further comprises a main supporting plate, wherein the main supporting plate is horizontally arranged, and a rear back plate is vertically arranged on one side of the main supporting plate; the main supporting plate is provided with a main cover plate, the main cover plate is a special-shaped plate body, the bottom of one side of the main cover plate is fixedly connected with the main supporting plate, the other side of the main cover plate is fixedly connected with the back plate, the top of the main cover plate is obliquely arranged, a plurality of heating blocks are arranged at the top of the main cover plate and are uniformly distributed above the main cover plate, the number of the absorption tanks is consistent with that of the heating blocks, and the absorption tanks are also positioned above the main cover plate;
the bottom of the main cover plate is fixedly connected with an installation frame, the installation frame is arranged in parallel with the absorption tank, and the stirrer rotating device is installed on the installation frame; the mounting frame comprises a top plate, a bottom plate, a first connecting column and a second connecting column, wherein the first connecting column is arranged at the bottom of one side of the top plate of the mounting frame, and the second connecting column is arranged at the bottom of the other side of the top plate of the mounting frame; the bottom of the first connecting column is fixedly connected with a driving motor, the driving belt pulley is fixedly arranged at the top of the driving motor, the bottom of the second connecting column is connected with a bottom plate, the belt rotating shaft penetrates through the top plate and the bottom plate, two bearings are arranged on the belt rotating shaft, the two bearings are respectively arranged on the top plate and the bottom plate, and the belt rotating shaft is rotatably connected on the top plate and the bottom plate through the bearings;
a groove is formed in one side of the top of the main cover plate and located below the mother liquid inlet, and the bottom of the groove is fixedly connected with one side, connected with the second connecting column, of the top plate.
The utility model has the advantages that:
when absorbing the inside liquid that is full of cavity and absorbing the experiment, the motor drives the drive pulley and rotates, the drive pulley passes through driving belt and drives the belt runner and rotate, the belt runner drives the magnet rotor and rotates, the stirring is the magnet structure, the magnet rotor is by N utmost point and S level with the stirring, under the effect of magnetic force, the magnet rotor keeps unanimous with stirring N level and S level all the time, consequently the magnet rotor is when rotating, it rotates to drive the stirring through magnetic force effect, it is inside rotatory at the absorption cavity to realize the stirring, the inside blood flow of simulation human body, be favorable to the experiment to go on, excellent in use effect.
The threaded connector of the liquid guide port is internally provided with an extremely fine through hole, and the absorption tank which is obliquely arranged in a matched mode can be favorable for discharging internal gas when the absorption tank is used, so that the internal gas is guaranteed, and the experimental effect is favorably guaranteed.
Drawings
Fig. 1 is a schematic view of the installation of the absorption cell of the present invention on a heating block.
Fig. 2 is a schematic sectional view of the absorption cell of the present invention mounted on a heating block.
Fig. 3 is a schematic view of the absorption tank of the present invention.
Fig. 4 is an exploded view of the absorption tank of the present invention.
List of reference numerals:
an absorption tank 1, a permeable membrane 11, a mother liquor cavity 12, a mother liquor outlet 13, a mother liquor inlet 14, an absorption cavity 15, a liquid guide port 16, a solvent inlet and outlet 17, a silica gel blank holder 18 and a stirrer 19;
a heat preservation system 4, a heating block 41, an absorption pool fixing clamp 42,
The stirrer rotating device 5, a driving motor 51, a driving belt pulley 52, a transmission belt 53, a belt rotating shaft 54, a bearing 541 and a magnet rotor 55;
Detailed Description
For making the technical scheme of the utility model clear more clearly and definitely, it is right to combine the drawing below the utility model discloses further describe, any is right the utility model discloses technical scheme's technical characteristic carries out the scheme that equivalent replacement and conventional reasoning reachs and all falls into the utility model discloses protection scope. The fixed connection, the fixed setting that mention in this embodiment are one or more in the publicly known connected mode that technical personnel in the field know such as hot melt integral type shaping, screw connection, welding, its connection principle is in the embodiment of the utility model provides a do not describe in detail.
An absorption tank structure of a drug absorption sampling system is characterized in that a permeation film is arranged in the middle of the absorption tank, one side of the permeation film is a mother liquor cavity, and the other side of the permeation film is an absorption cavity; a mother liquid outlet is formed in the top of the mother liquid cavity, a mother liquid inlet is formed in the bottom of the mother liquid cavity, and the mother liquid outlet is formed in the bottom of the mother liquid cavity; the top of the absorption cavity is provided with a liquid guide port, and one side of the bottom of the absorption cavity is provided with a solvent inlet and a solvent outlet.
Further, still include the heat preservation system, the heat preservation system includes heating piece and absorption cell fixation clamp, the absorption cell passes through the absorption cell fixation clamp to be fixed between the heating piece, and the heating piece heats the heat preservation to the absorption cell.
Furthermore, two silica gel blank holders are arranged between the mother liquor cavity and the absorption cavity of the absorption tank, and the permeable film is pressed between the two silica gel blank holders, so that the permeable film is vertically fixed inside the absorption tank; the mother liquid outlet, the mother liquid inlet and the solvent inlet and outlet are luer joints; the liquid guide port is a screwed joint, and a stirrer is arranged in the absorption cavity;
the absorption tank bottom still is provided with stirring son rotary device, stirring son rotary device includes driving motor, driving pulley, driving belt, belt pivot and magnet rotor, driving motor connects driving pulley, and the driving belt that registrates between driving pulley and the belt runner realizes the transmission through the belt, and the magnet rotor is connected at belt pivot top, and the magnet rotor is located stirring son below position.
The device further comprises a main supporting plate, wherein the main supporting plate is horizontally arranged, and a rear back plate is vertically arranged on one side of the main supporting plate; the main supporting plate is provided with a main cover plate, the main cover plate is a special-shaped plate body, the bottom of one side of the main cover plate is fixedly connected with the main supporting plate, the other side of the main cover plate is fixedly connected with the back plate, the top of the main cover plate is obliquely arranged, a plurality of heating blocks are arranged at the top of the main cover plate and are uniformly distributed above the main cover plate, the number of the absorption tanks is consistent with that of the heating blocks, and the absorption tanks are also positioned above the main cover plate;
the bottom of the main cover plate is fixedly connected with an installation frame, the installation frame is arranged in parallel with the absorption tank, and the stirrer rotating device is installed on the installation frame; the mounting frame comprises a top plate, a bottom plate, a first connecting column and a second connecting column, wherein the first connecting column is arranged at the bottom of one side of the top plate of the mounting frame, and the second connecting column is arranged at the bottom of the other side of the top plate of the mounting frame; the bottom of the first connecting column is fixedly connected with a driving motor, the driving belt pulley is fixedly arranged at the top of the driving motor, the bottom of the second connecting column is connected with a bottom plate, the belt rotating shaft penetrates through the top plate and the bottom plate, two bearings are arranged on the belt rotating shaft, the two bearings are respectively arranged on the top plate and the bottom plate, and the belt rotating shaft is rotatably connected on the top plate and the bottom plate through the bearings;
a groove is formed in one side of the top of the main cover plate and located below the mother liquid inlet, and the bottom of the groove is fixedly connected with one side, connected with the second connecting column, of the top plate.
The utility model has the advantages that:
when absorbing the inside liquid that is full of cavity and absorbing the experiment, the motor drives the drive pulley and rotates, the drive pulley passes through driving belt and drives the belt runner and rotate, the belt runner drives the magnet rotor and rotates, the stirring is the magnet structure, the magnet rotor is by N utmost point and S level with the stirring, under the effect of magnetic force, the magnet rotor keeps unanimous with stirring N level and S level all the time, consequently the magnet rotor is when rotating, it rotates to drive the stirring through magnetic force effect, it is inside rotatory at the absorption cavity to realize the stirring, the inside blood flow of simulation human body, be favorable to the experiment to go on, excellent in use effect.
The threaded connector of the liquid guide port is internally provided with an extremely fine through hole, and the absorption tank which is obliquely arranged in a matched mode can be favorable for discharging internal gas when the absorption tank is used, so that the internal gas is guaranteed, and the experimental effect is favorably guaranteed.
Claims (5)
1. An absorption tank structure of a drug absorption sampling system is characterized in that a permeation film is arranged in the middle of the absorption tank, one side of the permeation film is a mother liquor cavity, and the other side of the permeation film is an absorption cavity; a mother liquid outlet is formed in the top of the mother liquid cavity, a mother liquid inlet is formed in the bottom of the mother liquid cavity, and the mother liquid outlet is formed in the bottom of the mother liquid cavity; the top of the absorption cavity is provided with a liquid guide port, and one side of the bottom of the absorption cavity is provided with a solvent inlet and a solvent outlet.
2. The absorption cell structure of claim 1, further comprising a thermal insulation system, wherein the thermal insulation system comprises heating blocks and absorption cell fixing clips, the absorption cell is fixed between the heating blocks through the absorption cell fixing clips, and the heating blocks heat and insulate the absorption cell.
3. The absorption tank structure of claim 1, wherein two silica gel holders are disposed between the mother liquid cavity and the absorption cavity of the absorption tank, and the permeable membrane is pressed between the two silica gel holders, so that the permeable membrane is vertically fixed inside the absorption tank; the mother liquid outlet, the mother liquid inlet and the solvent inlet and outlet are luer joints; the liquid guide port is a screwed joint, and a stirrer is arranged in the absorption cavity;
the absorption tank bottom still is provided with stirring son rotary device, stirring son rotary device includes driving motor, driving pulley, driving belt, belt pivot and magnet rotor, driving motor connects driving pulley, and the driving belt that registrates between driving pulley and the belt runner realizes the transmission through the belt, and the magnet rotor is connected at belt pivot top, and the magnet rotor is located stirring son below position.
4. The absorption cell structure of claim 3, further comprising a main support plate, wherein the main support plate is horizontally disposed, and a back plate is vertically disposed on one side of the main support plate; the main supporting plate is provided with a main cover plate, the main cover plate is a special-shaped plate body, the bottom of one side of the main cover plate is fixedly connected with the main supporting plate, the other side of the main cover plate is fixedly connected with the back plate, the top of the main cover plate is obliquely arranged, a plurality of heating blocks are arranged at the top of the main cover plate and are uniformly distributed above the main cover plate, the number of the absorption tanks is consistent with that of the heating blocks, and the absorption tanks are also positioned above the main cover plate;
the bottom of the main cover plate is fixedly connected with an installation frame, the installation frame is arranged in parallel with the absorption tank, and the stirrer rotating device is installed on the installation frame; the mounting frame comprises a top plate, a bottom plate, a first connecting column and a second connecting column, wherein the first connecting column is arranged at the bottom of one side of the top plate of the mounting frame, and the second connecting column is arranged at the bottom of the other side of the top plate of the mounting frame; the belt conveyor is characterized in that the bottom of the first connecting column is fixedly connected with a driving motor, a driving belt pulley is fixedly arranged at the top of the driving motor, the bottom of the second connecting column is connected with a bottom plate, a belt rotating shaft penetrates through the top plate and the bottom plate, two bearings are arranged on the belt rotating shaft and are respectively installed on the top plate and the bottom plate, and the belt rotating shaft is rotatably connected with the top plate and the bottom plate through the bearings.
5. The absorption cell structure of claim 4, wherein a groove is formed on one side of the top of the main cover plate, the groove is located below the mother liquid inlet, and the bottom of the groove is fixedly connected with one side of the top plate connected with the second connecting column.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110045071A (en) * | 2019-04-19 | 2019-07-23 | 禄根仪器(镇江)有限公司 | A kind of absorption pool structure of drug absorption sampling system |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110045071A (en) * | 2019-04-19 | 2019-07-23 | 禄根仪器(镇江)有限公司 | A kind of absorption pool structure of drug absorption sampling system |
CN110045071B (en) * | 2019-04-19 | 2024-09-17 | 禄根仪器(镇江)有限公司 | Absorption cell structure of medicine absorption sampling system |
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