CN210743373U - Plateau nature human disease model preparation environmental simulation system - Google Patents
Plateau nature human disease model preparation environmental simulation system Download PDFInfo
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- CN210743373U CN210743373U CN201921902600.1U CN201921902600U CN210743373U CN 210743373 U CN210743373 U CN 210743373U CN 201921902600 U CN201921902600 U CN 201921902600U CN 210743373 U CN210743373 U CN 210743373U
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Abstract
The utility model discloses a highland nature human disease model preparation environmental simulation system, including the integrated base of functional equipment and the storehouse of raising of setting on the integrated base of functional equipment, raising the storehouse and having electrodeless regulation and control little negative pressure device, plateau low oxygen environment analogue means, plateau illumination environment analogue means, plateau temperature environment analogue means, plateau humidity environment analogue means, animal behavior remote observation unit, be provided with a plurality of metabolism cages in raising the storehouse, be provided with observation window and a plurality of operation window around raising the storehouse on the box, be provided with little article transmission window and big article transmission window on the left and right box of raising the storehouse respectively, the metabolism cage is still including setting up feeding hopper, drinking water bottle on the metabolism cage and setting up at the collection excrement fill, urine discharge port, the excrement and urine discharge port of metabolism cage below. Can well simulate plateau environment, can cultivate multiple animals simultaneously, make the mould animal many.
Description
Technical Field
The utility model belongs to the technical field of animal experimental facilities, concretely relates to plateau nature human disease model preparation environmental simulation system.
Background
The plateau environment simulation system can be manufactured in non-plateau areas to generate different altitude and climate conditions, various plateau anoxic environments are simulated, experimental animals can reach expected plateau reaction symptoms according to experimental requirements within a certain time, the experimental animals can show plateau diseases, plateau disease model animals are provided for plateau disease researchers, and medicines for treating or preventing the plateau diseases are convenient to research. The existing environment simulation system can simulate and realize plateau illumination and low oxygen environment, but the success rate of models is low, the death rate of animals is high, and the types of modeling animals are single.
Disclosure of Invention
The utility model aims to provide a: provides a plateau human disease model preparation environment simulation system, and solves the problems of low model success rate, high animal mortality rate and single type of modeling animals in the conventional plateau environment simulation system.
The utility model adopts the technical scheme as follows:
the utility model provides a plateau nature human disease model preparation environmental simulation system, includes functional equipment integrated base and sets up the feed bin on functional equipment integrated base, feed bin has electrodeless regulation and control micro negative pressure device, plateau low oxygen environment analogue means, plateau illumination environment analogue means, plateau temperature environment analogue means, plateau humidity environment analogue means, animal behaviourology remote observation unit, be provided with a plurality of metabolism cages in the feed bin, be provided with observation window and a plurality of operation window around the feed bin on the box, be provided with little article pass-through box and big article pass-through box on the box about the feed bin respectively, the metabolism cage is still including setting up feeding hopper, drinking water bottle on the metabolism cage and setting up gather excrement fill, urine discharge port, excrement discharge port below the metabolism cage.
Furthermore, the electrodeless regulation and control micro-negative pressure device comprises an air inlet system, an air exhaust system and a Honeyville or Siemens regulation and control module, wherein the air inlet system is arranged in the functional equipment integration base, and the air exhaust system is arranged at the top of the feeding bin.
Further, plateau low oxygen environment analogue means includes the inert gas source, the inert gas source is connected with the air inlet system, be provided with the proportion formula pneumatic valve between inert gas source and the air inlet system, still including setting up the embedded oxygen apparatus in raising the storehouse.
Further, the plateau illumination environment simulation device comprises a visible warm light system and an illumination brightness stepless control system, wherein the visible warm light system is arranged at the top of the feeding bin.
Further, the plateau temperature environment simulation device comprises a cooling system, a heating system, a temperature control system and a temperature acquisition and display system.
Further, plateau humidity environment simulation device includes humidification system, dehumidification system, humidity control system and humidity acquisition display system.
Furthermore, the animal behavior remote observation unit comprises a Comms high-definition image acquisition system, a digital video transmission system, a frequency hardware decompression card and a video display system.
To sum up, owing to adopted above-mentioned technical scheme, the beneficial effects of the utility model are that:
1. the utility model discloses full automatic control system of non needs artificial observation and manual regulation isolator internal environment, but artificial regulation more can be direct simulate out the experiment environment as required, can effectively reduce the emergence of the unexpected condition for automatic control's environmental simulation.
2. A plurality of metabolism cages that this system set up can cultivate multiple animal simultaneously, and the molding animal is many.
3. The utility model discloses a plateau pressure, temperature, humidity and low oxygen environment can be simulated well to the system, still has animal behavior remote observation function, has ensured operation process's traceability after real time monitoring and the experiment end in the experimentation.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a front view of the environmental simulation system for preparing a model of a high altitude human disease according to the present invention;
FIG. 2 is a schematic view of a three-dimensional structure of a plateau human disease model preparation environment simulation system of the present invention;
FIG. 3 is a schematic perspective view of a metabolic cage;
the labels in the figure are: 1-a functional equipment integration base, 2-a feeding bin, 3-a metabolism cage, 4-an observation window, 5-an operation window, 6-a small object transfer window, 7-a large object transfer window, 8-a feeding hopper, 9-a drinking water bottle, 10-a feces gathering hopper, 11-a urine discharge port, 12-a feces discharge port, 13-an air inlet system, 14-an air exhaust system, 15-a plateau illumination environment simulation device, 16-a plateau temperature environment simulation device, 17-a plateau humidity environment simulation device, 18-an animal behavior remote observation unit and 19-a functional control panel.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the invention, i.e., the described embodiments are only some, but not all embodiments of the invention. The components of embodiments of the present invention, as generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiment of the present invention, all other embodiments obtained by the person skilled in the art without creative work belong to the protection scope of the present invention.
It is noted that relational terms such as "first" and "second," and the like, may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
The utility model provides a highland nature human disease model preparation environmental simulation system, including function equipment integration base 1 and the storehouse 2 of raising of setting on function equipment integration base 1, raise storehouse 2 and have electrodeless regulation and control micro negative pressure device, plateau low oxygen environment analogue means, plateau illumination environment analogue means 15, plateau temperature environment analogue means 16, plateau humidity environment analogue means 17, animal behavior remote observation unit 18, be provided with a plurality of metabolism cages 3 in the storehouse 2, be provided with observation window 4 and a plurality of operation window 5 around the storehouse 2 on the box, be provided with little article pass-through box 6 and big article pass-through box 7 respectively about the storehouse 2 on the box, metabolism cage 3 is still including setting up feeding hopper 8, drinking water bottle 9 on metabolism cage 3 and setting up gathering excrement fill 10, urine discharge port 11, the excrement collection fill 10 of metabolism cage 3 below, A fecal discharge port 12.
The working principle of the embodiment is as follows: all functions of the device are controlled by a function control panel 19 arranged on the feeding bin 2, and the device adopts 304 stainless steel in appearance and has good air tightness. After the experimental animal is fed into the feeding bin 2, the small object transfer window 6 and the large object transfer window 7 are closed, and the internal environment simulation of the feeding bin 2 is realized through the function control panel 19. Adjust the pressure of raising the interior of storehouse 2 through electrodeless regulation and control little negative pressure device, adjust through plateau low oxygen environment analogue means and raise the interior oxygen content of storehouse 2, when the light is required, open ultraviolet lamp and light through plateau illumination environment analogue means 15, adjust the temperature through plateau temperature environment analogue means 16, adjust through plateau humidity environment analogue means 17 and raise the interior humidity of storehouse 2, the action that can monitor the animal through animal behaviours remote observation unit 18, a plurality of metabolism cages 3 in raising the storehouse 2 are equipped with feeding hopper 8, drinking water bottle 9 can carry out the food intake, the drinking water content is fixed, gather excrement fill 10, urine discharge port 11, excrement discharge port 12 is convenient for the urine and the excrement and urine conventional detection of model animal, and a plurality of metabolism cages 3 that this system set up can cultivate multiple animal simultaneously, the molding animal is many.
Example 2
On the basis of embodiment 1, the plateau human disease model preparation environment simulation system provided comprises an air inlet system 13, an air outlet system 14 and a Honeyville or Siemens regulation and control module, wherein the air inlet system 13 is arranged in a functional equipment integration base 1, and the air outlet system 14 is arranged at the top of a feeding bin 2.
The working principle of the embodiment is as follows: an air inlet fan unit is integrated in an air inlet system 13 of the system, and an air outlet fan unit is integrated in an air outlet system 14 of the system. Because the feeding bin 2 can be sealed, the pressure difference is adjusted by changing the air quantity of the fan, the air inlet fan unit and the air exhaust fan unit are both communicated with the feeding bin 2, the micro negative pressure (0.5-1.0 Pa) can be formed in the environment in the system by adjusting the pressure difference value of air inlet and air exhaust, and the system is provided with a Honeyville or Siemens regulation and control module, so that stepless regulation and control can be performed in the set pressure difference standard to ensure that the system simulates the micro negative pressure of the altitude (3000-7000 m). And the air inlet and exhaust pipes are provided with high-efficiency air filters, so that the air entering the feeding bin 2 is clean.
Example 3
The plateau hypoxia environment simulation device comprises an inert gas source, the inert gas source is connected with an air inlet system 13, a proportional type gas valve is arranged between the inert gas source and the air inlet system 13, and the plateau hypoxia environment simulation device further comprises an embedded oxygen tester arranged in a feeding bin 2.
The working principle of the embodiment is as follows: the inert gas source can be an inert gas storage tank or a liquid inert gas storage tank. When simulating the low oxygen environment, the external inert gas storage tank is connected with the air inlet system 13. The proportional gas valve and the embedded oxygen measuring instrument are both connected with the function control panel 19, the concentration is displayed through an oxygen concentration meter on the function control panel 19 to adjust the proportional gas valve, and the oxygen concentration is reduced by adding inert gas. When the oxygen concentration in the bin is high, the air valve between the inert gas storage tank and the air inlet system is manually opened, the inert gas inlet amount is adjusted, the oxygen concentration in the bin is reduced, the oxygen concentration display on the control panel is observed, the opening size of the air valve is adjusted, the required oxygen concentration is achieved, and the simulation of the plateau anoxic environment is realized through the adjustment. The inert gas adopted by the technical scheme is the inert gas which is harmless to life bodies.
Example 4
On the basis of embodiment 1, the plateau lighting environment simulation device 15 includes a visible warm light system and an illumination brightness stepless control system, and the visible warm light system is disposed on the top of the feeding bin 2.
The working principle of the embodiment is that the system integrates a visible warm light system (capable of simulating plateau infrared rays and ultraviolet rays) and an illumination brightness electrodeless control system, when illumination is needed, an ultraviolet lamp and an illuminating lamp can be started through a lighting system, brightness adjustment can be achieved according to requirements, and a plateau high ultraviolet ray illumination environment is achieved through a fluorescent lamp and an ultraviolet lamp.
Example 5
The plateau temperature environment simulation device 16 comprises a cooling system, a heating system, a temperature control system and a temperature acquisition and display system.
The working principle of the embodiment is as follows: the system is provided with a cooling system, a heating system, a temperature control system and a temperature acquisition and display system, so that the temperature in the system can be steplessly regulated and controlled to ensure that the plateau temperature environment with the altitude (3000 m-7000 m) is simulated, and the temperature regulation is realized by a cold-warm air blower, namely the principle same as that of an air conditioner.
Example 6
On the basis of embodiment 1, the plateau humidity environment simulation device 17 includes a humidification system, a dehumidification system, a humidity control system, and a humidity acquisition and display system.
The working principle of the embodiment is as follows: the system is provided with a humidifying system, a dehumidifying system, a humidity control system and a humidity acquisition and display system, so that the humidity in the system can be steplessly regulated and controlled, and the plateau humidity environment with the altitude of 3000-7000 m can be simulated.
Example 7
On the basis of embodiment 6, the plateau human disease model preparation environment simulation system is provided, and the animal behavior remote observation unit 18 includes a Coms high definition image acquisition system, a digital video transmission system, a frequency hardware decompression card, and a video display system.
The working principle of the embodiment is as follows: a Comms high-definition image acquisition system (supporting an ICP/IP network communication protocol), a digital video transmission system, a frequency hardware decompression card (a USB or PCI interface user selects) and a video display system (a user has the self-provided) are configured in the system, so that the real-time monitoring in the experimental process and the traceability of the operation process after the experiment is finished are ensured. For example, install high-accuracy camera above raising storehouse 2, carry on cell-phone APP, can 360 the action of control animal to can real-time video recording, image acquisition etc. realize the zoology action through the control video recording and observe.
The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.
Claims (7)
1. The utility model provides a plateau nature human disease model preparation environmental simulation system, includes functional equipment integrated base (1) and sets up raising storehouse (2) on functional equipment integrated base (1), raising storehouse (2) and have electrodeless regulation and control little negative pressure device, plateau low oxygen environment analogue means, plateau illumination environment analogue means (15), plateau temperature environment analogue means (16), plateau humidity environment analogue means (17), animal behavior remote observation unit (18), its characterized in that: the feeding bin is characterized in that a plurality of metabolism cages (3) are arranged in the feeding bin (2), an observation window (4) and a plurality of operation windows (5) are arranged on the front box body and the rear box body of the feeding bin (2), small object transfer windows (6) and large object transfer windows (7) are respectively arranged on the left box body and the right box body of the feeding bin (2), and each metabolism cage (3) further comprises a feeding hopper (8) arranged on the metabolism cage (3), a drinking water bottle (9), a feces collecting hopper (10) arranged below the metabolism cage (3), a urine discharge port (11) and a feces discharge port (12).
2. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the electrodeless regulation and control micro negative pressure device comprises an air inlet system (13), an air exhaust system (14) and a Honeyville or Siemens regulation and control module, wherein the air inlet system (13) is arranged in the functional equipment integration base (1), and the air exhaust system (14) is arranged at the top of the feeding bin (2).
3. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the plateau hypoxia environment simulation device comprises an inert gas source, wherein the inert gas source is connected with an air inlet system (13), a proportional gas valve is arranged between the inert gas source and the air inlet system (13), and the plateau hypoxia environment simulation device further comprises an embedded oxygen tester arranged in a feeding bin (2).
4. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the plateau illumination environment simulation device (15) comprises a visible warm light system and an illumination brightness stepless control system, wherein the visible warm light system is arranged at the top of the feeding bin (2).
5. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the plateau temperature environment simulation device (16) comprises a cooling system, a heating system, a temperature control system and a temperature acquisition and display system.
6. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the plateau humidity environment simulation device (17) comprises a humidifying system, a dehumidifying system, a humidity control system and a humidity acquisition and display system.
7. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the animal behavior remote observation unit (18) comprises a Comms high-definition image acquisition system, a digital video transmission system, a frequency hardware decompression card and a video display system.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921902600.1U CN210743373U (en) | 2019-11-06 | 2019-11-06 | Plateau nature human disease model preparation environmental simulation system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921902600.1U CN210743373U (en) | 2019-11-06 | 2019-11-06 | Plateau nature human disease model preparation environmental simulation system |
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| Publication Number | Publication Date |
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| CN210743373U true CN210743373U (en) | 2020-06-12 |
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| CN201921902600.1U Active CN210743373U (en) | 2019-11-06 | 2019-11-06 | Plateau nature human disease model preparation environmental simulation system |
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Effective date of registration: 20210721 Address after: Floor 1-2, building 14, 1919 Shuangyan Road, Chengdu cross strait science and Technology Industrial Development Park, Wenjiang District, Chengdu, Sichuan 610000 Patentee after: Chengdu Senwei experimental animal Co.,Ltd. Address before: No. 904, office building, Life Science Park, start industrial park, South Park, high tech Zone, Chengdu, Sichuan 610041 Patentee before: Chengdu Dashuo experimental animal Co.,Ltd. |